Below a list of publications is given related to LEGend.
Title | Authors | Date | Keywords | Issue name |
---|---|---|---|---|
‘I am happy to be listened to’: co-creation of a simple tool to measure women’s experiences of respectful maternity care in urban Tanzania. | Sequeira D'mello B, Housseine N, Kidanto HL, Maaløe N, van Roosmalen J, Meyrowitsch DW, van den Akker T, Muniro Z, Polin E, Ambokile N, Festo C, Sørensen JB, Sando D | 2024-12-31 | Dar es Salaam, Person-centered maternity care, disrespect and abuse, experience of care, measurement tool, mistreatment, respectful maternity care, urban health | Global health action |
Effect of thyroid status modulation on pituitary and peripheral hormone concentrations in healthy older subjects. | van der Spoel E, Cornet S, Zutinic A, Ballieux B, Slagboom PE, Pijl H, van Heemst D | 2024-12-03 | Neuroendocrinology | |
Tissue-specific methylomic responses to a lifestyle intervention in older adults associate with metabolic and physiological health improvements. | Sinke L, Beekman M, Raz Y, Gehrmann T, Moustakas I, Boulinguiez A, Lakenberg N, Suchiman E, Bogaards FA, Bizzarri D, van den Akker EB, Waldenberger M, Butler-Browne G, Trollet C, de Groot CPGM, Heijmans BT, Slagboom PE | 2024-12-01 | DNA methylation, epigenomics, functional genomics, healthy aging, lifestyle, metabolism, muscle | Aging cell |
On the limits of communication: The liminal positioning of older adults and processes of self-ageism and ageism. | Schuurman B, Achterberg WP, Abma TA, Lindenberg J | 2024-12-01 | Age identification, Communication, Liminality, Self-ageism, Social identity | Journal of aging studies |
Predicting the risks and recognizing the signs: a two-year prospective population-based study on pregnant women with uterine rupture in The Netherlands. | Overtoom EM, Huynh TN, Rosman AN, Zwart JJ, Schaap TP, Vogelvang TE, van den Akker T, Bloemenkamp KWM | 2024-12-01 | CTG tracings, Uterine rupture, adverse outcome, maternal morbidity, perinatal morbidity | The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians |
Blood based immune biomarkers associated with clinical frailty scale in older patients with melanoma receiving checkpoint inhibitor immunotherapy. | Tran Van Hoi E, Santegoets SJ, Mooijaart SP, Van Heemst D, Özkan A, Verdegaal EME, Slingerland M, Kapiteijn E, van der Burg SH, Portielje JEA, Welters MJP, de Glas NA | 2024-11-27 | Frailty, Immune biomarkers, Immunotherapy by checkpoint inhibition, Melanoma cancer | Immunity & ageing : I & A |
Mitochondrial DNA abundance and circulating metabolomic profiling: Multivariable-adjusted and Mendelian randomization analyses in UK Biobank. | Luo J, le Cessie S, van Dijk KW, Hägg S, Grassmann F, van Heemst D, Noordam R | 2024-11-24 | Mitochondrion | |
Activities of persons with dementia at home and after nursing home admission: A survey study. | Groenendaal M, Smaling HJA, Achterberg WP, Caljouw MAA | 2024-11-22 | Activities, Assessment, Dementia, Informal caregivers, Nursing home, Transition | Geriatric nursing (New York, N.Y.) |
Self-Reflection as a Starting Point: Observations in Global Health Research. | Bakker W, van den Akker T, Stekelenburg J | 2024-11-20 | Global health, science and practice | |
The use of wearable technology in studies in older adults with cancer: a systematic review. | Duin JJ, Baltussen JC, Albalak G, van Dam van Isselt EF, Portielje JEA, Mooijaart SP, Soto-Perez-de-Celis E, van den Bos F | 2024-11-20 | cancer, digital health, geriatric oncology, geriatrics, older adult, oncology, systematic review, wearable electronic devices, wearable technology | The oncologist |
Which Characteristics are Associated With Going Outside for People Living With Dementia in Nursing Homes? A Cross-Sectional Study. | Velde-van Buuringen MV, Verbeek-Oudijk D, Verbeek H, Achterberg WP, Caljouw MAA | 2024-11-12 | dementia, going outside, nursing homes, quality of life | Journal of applied gerontology : the official journal of the Southern Gerontological Society |
A Micro-Flow Liquid Chromatography-Mass Spectrometry Method for the Quantification of Oxylipins in Volume-Limited Human Plasma. | He B, Ramautar R, Beekman M, Slagboom PE, Harms A, Hankemeier T | 2024-11-11 | micro–liquid chromatography (LC)–mass spectrometry (MS), oxylipins, sensitivity enhancement, volume‐limited plasma | Electrophoresis |
Association between metabolomics-based biomarker scores and 10-year cognitive decline in men and women. The Doetinchem Cohort Study. | Smit AP, Herber GM, Kuiper LM, Rietman ML, Wesenhagen KEJ, Picavet HSJ, Slagboom PE, Verschuren WMM | 2024-11-04 | biomarker, cognitive function, longitudinal, metabolomics, older people, sex differences | Age and ageing |
Timing of cesarean section for prolonged labor in urban Tanzania: A criterion-based audit. | Kujabi ML, Housseine N, Kabanda I, Msumi R, Maembe L, Sangalala M, Hudson M, Hansen S, Macha A, Sequeira D'mello B, Meyrowitsch DW, Konradsen F, Jensen AK, Hussein K, Maaløe N, van den Akker T | 2024-11-01 | PartoMa, Tanzania, childbirth, dystocia, guidelines, low-resource setting, pregnancy, urban | AJOG global reports |
The association of overweight, obesity, and long-term obesity with SARS-CoV-2 infection: a meta-analysis of 9 population-based cohorts from the Netherlands Cohorts Consortium. | Loef B, Boer JMA, Beekman M, Campman SL, Hoogendijk EO, Huider F, Pagen DME, Splinter MJ, van der Velde JHPM, Boomsma DI, Dagnelie PC, van Dongen J, de Geus EJC, Huisman M, Ikram MA, Koster A, Licher S, Mierau JO, de Mutsert R, Picavet HSJ, Rosendaal FR, Schram MT, Slagboom PE, van der Spoel E, Stronks K, Verschuren WMM, van den Berg SW | 2024-10-31 | International journal of obesity (2005) | |
Design of the VOILA-intervention study: A 12-week nutrition and resistance exercise intervention in metabolic or mobility compromised Dutch older adults and the response on immune-metabolic, gut and muscle health parameters. | Kramer CS, Monsegue A, Morwani-Mangnani J, Grootswagers P, Beekman M, Slagboom PE, Verdijk LB, de Groot LC | 2024-10-26 | Biological age, gerontology, gut health, intervention, metabolic health, nutrition, resistance exercise | Mechanisms of ageing and development |
The effect of histological and subclinical chorioamnionitis and funisitis on breathing effort in premature infants at birth: a retrospective cohort study. | Panneflek TJR, Dekker J, Kuypers KLAM, van der Meeren LE, Polglase GR, Hooper SB, van den Akker T, Pas ABT | 2024-10-25 | Breathing, Chorioamnionitis, Funisitis, Neonatology, Resuscitation | European journal of pediatrics |
Association between TTV viremia, chronic inflammation, and ischemic heart disease risk: Insights from MARK-AGE and Report-Age projects. | Giacconi R, Piacenza F, Maggi F, Bürkle A, Moreno Villanueva M, Mancinelli L, Spezia PG, Novazzi F, Drago Ferrante F, Minosse C, Grossi PA, Mancini N, Cecati M, Dollé MET, Jansen E, Grune T, Gonos ES, Franceschi C, Capri M, Weinberger B, Sikora E, Debacq-Chainiaux F, Stuetz W, Hurme M, Slagboom PE, Bernhardt J, Gentilini D, Calzari L, Di Rosa M, Bonfigli AR, Galeazzi R, Cherubini A, Lattanzio F, Provinciali M, Malavolta M | 2024-10-24 | Ischemic Heart Disease, Torquetenovirus, aging, inflammation | The journals of gerontology. Series A, Biological sciences and medical sciences |
Risk assessment and management strategies in older patients with acute pulmonary embolism. | Luijten D, Abbel D, Cannegieter SC, Eikenboom J, den Exter PL, Gussekloo J, Huisman MV, van Mens TE, Tahir L, Trompet S, Mooijaart SP, Klok FA | 2024-10-23 | Adult, Clinical decision-making, Early discharge, Emergency care, Geriatrics, Outpatient care, Pulmonary embolism, frail older | Journal of thrombosis and haemostasis : JTH |
Increased 1H-NMR metabolomics-based health score associates with declined cognitive performance and functional independence in older adults at risk of cardiovascular disease. | Zonneveld MH, Al Kuhaili N, Mooijaart SP, Slagboom PE, Jukema JW, Noordam R, Trompet S | 2024-10-22 | Cognition, Functional independence, Metabolomics | GeroScience |
Biomarkers of endothelial dysfunction and cognition: A two-step IPD meta-analysis. | Beran M, Jansen WJ, Oomens JE, Moonen JEF, Slagboom PE, Huisman M, Kok AAL, Nooyens ACJ, Verschuren WMM, Stehouwer CDA, Schalkwijk C, Köhler S, Beekman M, Slagboom PE, Wolters FJ, Ikram MA, Vallerga CL, van Meurs JBJ, Ghanbari M, Vonk JMJ, Geerlings MI, van Sloten TT, Schram MT | 2024-10-20 | biomarkers, cognition, cohort, endothelial dysfunction, meta‐analysis | Alzheimer's & dementia : the journal of the Alzheimer's Association |
Association of Glasgow Prognostic Score with frailty, mortality and adverse health outcomes in older patients with cancer: A prospective cohort study. | van Holstein Y, Trompet S, van Munster BC, van den Berkmortel PJE, van Heemst D, de Glas NA, Slingerland M, Slagboom PE, Holterhues C, Labots G, Mooijaart SP, Portielje JEA, van den Bos F | 2024-10-14 | Albumin, C-reactive protein, Functional dependence, Geriatric oncology, Health-related quality of life | Journal of geriatric oncology |
Use of antithrombotic therapy and the risk of cardiovascular outcomes and bleeding in cancer patients at the end of life: A Danish nationwide cohort study. | Søgaard M, Ørskov M, Jensen M, Goedegebuur J, Kempers EK, Visser C, Geijteman ECT, Abbel D, Mooijaart SP, Geersing GJ, Portielje J, Edwards A, Aldridge SJ, Akbari A, Højen AA, Klok FA, Noble S, Cannegieter S, Ording AG | 2024-10-09 | Cancer, anticoagulation, deprescribing, palliative care, platelet inhibitor | Journal of thrombosis and haemostasis : JTH |
Association of a composite trait for anthropometrics, adiposity and energy expenditure with cardiometabolic diseases: An age-stratified cohort and genetic risk score analysis. | Meulmeester FL, van Dijk KW, van Heemst D, Noordam R | 2024-10-02 | Mendelian randomization, UK Biobank, body composition, cardiometabolic disease, genome‐wide association study, geroscience | Diabetes, obesity & metabolism |
Sex differences in cognitive functioning in patients with heart failure. | Kuipers S, Kappelle LJ, Greving JP, Amier RP, de Bresser J, Bron EE, Leeuwis AE, Marcks N, den Ruijter HM, Biessels GJ, Exalto LG | 2024-09-27 | Cerebrovascular disorders, Cognition, Heart failure, Men, Sex, Women | International journal of cardiology |
A Novel Metabolomic Aging Clock Predicting Health Outcomes and Its Genetic and Modifiable Factors. | Jia X, Fan J, Wu X, Cao X, Ma L, Abdelrahman Z, Zhao F, Zhu H, Bizzarri D, Akker EBVD, Slagboom PE, Deelen J, Zhou D, Liu Z | 2024-09-27 | aging, biological age, genetic determinant, metabolomic, modifiable factor, mortality | Advanced science (Weinheim, Baden-Wurttemberg, Germany) |
Association between cognitive functioning and health-related quality of life and its mediation by depressive symptoms in older patients with kidney failure. | Demirhan I, van Oevelen M, Skalli Z, Voorend CGN, Mooijaart SP, Meuleman Y, Verhaar MC, Bos WJW, van Buren M, Abrahams AC | 2024-09-26 | Cognitive functioning, Kidney failure, Older patients, Quality of life | Journal of nephrology |
Large-scale genome-wide interaction analyses on multiple cardiometabolic risk factors to identify age-specific genetic risk factors. | Ao L, van Heemst D, Luo J, Teder-Laving M, Mägi R, Frikke-Schmidt R, Willems van Dijk K, Noordam R | 2024-09-25 | Age-specific effects, Cardiometabolic risk factors, Gene-age interaction, Genome-wide interaction analyses | GeroScience |
Professional identity formation of medical students in relation to older persons’ healthcare: exploring the views of older persons living in the Netherlands – a qualitative study. | Moll-Jongerius A, Langeveld K, Gussekloo J, Kramer A, Achterberg WP | 2024-09-25 | education, medical, geriatric medicine, medical education & training, nursing homes, primary health care, qualitative research | BMJ open |
How well does the academic performance of Ethiopian anaesthetists predict their National Licensing Examination scores: a cross-sectional study. | Asemu YM, Yigzaw T, Ayalew F, Scheele F, van den Akker T | 2024-09-24 | Health Services Accessibility, Health Workforce, Health policy, Human resource management, MEDICAL EDUCATION & TRAINING | BMJ open |
Incidence, Causes and Outcomes of Postpartum Hemorrhage in Eastern Ethiopia: A Multicenter Surveillance Study. | Girma S, Tura AK, Ahmed R, Knight M, van den Akker T | 2024-09-19 | Ethiopia, Maternal death, Obstetric surveillance, Postpartum hemorrhage | Maternal and child health journal |
Impact of COVID-19 mitigation measures on perinatal outcomes in the Netherlands. | Burgos-Ochoa L, Bertens LC, Boderie NW, Gravesteijn BY, Obermann-Borst S, Rosman A, Struijs J, Labrecque J, de Groot CJ, Been JV | 2024-09-18 | Public health | |
Challenges and recommendations for the translation of biomarkers of aging. | Herzog CMS, Goeminne LJE, Poganik JR, Barzilai N, Belsky DW, Betts-LaCroix J, Chen BH, Chen M, Cohen AA, Cummings SR, Fedichev PO, Ferrucci L, Fleming A, Fortney K, Furman D, Gorbunova V, Higgins-Chen A, Hood L, Horvath S, Justice JN, Kiel DP, Kuchel GA, Lasky-Su J, LeBrasseur NK, Maier AB, Schilling B, Sebastiano V, Slagboom PE, Snyder MP, Verdin E, Widschwendter M, Zhavoronkov A, Moqri M, Gladyshev VN | 2024-09-16 | Nature aging | |
Development and validation of cardiometabolic risk predictive models based on LDL oxidation and candidate geromarkers from the MARK-AGE data. | Valeanu A, Margina D, Weber D, Stuetz W, Moreno-Villanueva M, Dollé MET, Jansen EH, Gonos ES, Bernhardt J, Grubeck-Loebenstein B, Weinberger B, Fiegl S, Sikora E, Mosieniak G, Toussaint O, Debacq-Chainiaux F, Capri M, Garagnani P, Pirazzini C, Bacalini MG, Hervonen A, Slagboom PE, Talbot D, Breusing N, Frank J, Bürkle A, Franceschi C, Grune T, Gradinaru D | 2024-09-14 | LDL oxidation, MARK-AGE, cardiometabolic risk, machine learning, vascular ageing | Mechanisms of ageing and development |
Health workers’ perspectives on the quality of maternal and newborn health care around the time of childbirth: Results of the Improving MAternal Newborn carE in the EURO Region (IMAgiNE EURO) project in 12 countries of the World Health Organization European Region. | Valente EP, Mariani I, Bomben A, Morano S, Gemperle M, Otelea MR, Miani C, Elden H, Sarantaki A, Costa R, Baranowska B, König-Bachmann M, Kongslien S, Drandić D, Rozée V, Nespoli A, Abderhalden-Zellweger A, Nanu I, Batram-Zantvoort S, Linden K, Metallinou D, Dias H, Tataj-Puzyna U, D'Costa E, Nedberg IH, Kurbanović M, de La Rochebrochard E, Fumagalli S, Grylka-Baeschlin S, Handra CM, Zaigham M, Orovou E, Barata C, Szlendak B, Zenzmaier C, Vik ES, Liepinaitienė A, Drglin Z, Arendt M, Sacks E, Lazzerini M | 2024-09-06 | Journal of global health | |
Validity and reliability of the Pain Assessment in Impaired Cognition 15 (PAIC15) observation scale in persons with aphasia. | de Vries NJ, Smaling HJA, van der Steen JT, Achterberg WP | 2024-09-05 | Aphasia, Pain observation instrument, Pain scales, Self-report pain | BMC neurology |
A Large-Scale Genome-Wide Gene-Sleep Interaction Study in 732,564 Participants Identifies Lipid Loci Explaining Sleep-Associated Lipid Disturbances. | Noordam R, Wang W, Nagarajan P, Wang H, Brown MR, Bentley AR, Hui Q, Kraja AT, Morrison JL, O'Connel JR, Lee S, Schwander K, Bartz TM, de Las Fuentes L, Feitosa MF, Guo X, Hanfei X, Harris SE, Huang Z, Kals M, Lefevre C, Mangino M, Milaneschi Y, van der Most P, Pacheco NL, Palmer ND, Rao V, Rauramaa R, Sun Q, Tabara Y, Vojinovic D, Wang Y, Weiss S, Yang Q, Zhao W, Zhu W, Abu Yusuf Ansari M, Aschard H, Anugu P, Assimes TL, Attia J, Baker LD, Ballantyne C, Bazzano L, Boerwinkle E, Cade B, Chen HH, Chen W, Ida Chen YD, Chen Z, Cho K, De Anda-Duran I, Dimitrov L, Do A, Edwards T, Faquih T, Hingorani A, Fisher-Hoch SP, Gaziano JM, Gharib SA, Giri A, Ghanbari M, Grabe HJ, Graff M, Gu CC, He J, Heikkinen S, Hixson J, Ho YL, Hood MM, Houghton SC, Karvonen-Gutierrez CA, Kawaguchi T, Kilpeläinen TO, Komulainen P, Lin HJ, Linchangco GV, Luik AI, Ma J, Meigs JB, McCormick JB, Menni C, Nolte IM, Norris JM, Petty LE, Polikowsky HG, Raffield LM, Rich SS, Riha RL, Russ TC, Ruiz-Narvaez EA, Sitlani CM, Smith JA, Snieder H, Sofer T, Shen B, Tang J, Taylor KD, Teder-Laving M, Triatin R, Tsai MY, Völzke H, Westerman KE, Xia R, Yao J, Young KL, Zhang R, Zonderman AB, Zhu X, Below JE, Cox SR, Evans M, Fornage M, Fox ER, Franceschini N, Harlow SD, Holliday E, Ikram MA, Kelly T, Lakka TA, Lawlor DA, Li C, Liu CT, Mägi R, Manning AK, Matsuda F, Morrison AC, Nauck M, North KE, Penninx BW, Province MA, Psaty BM, Rotter JI, Spector TD, Wagenknecht LE, Willems van Dijk K, Study LC, Jaquish CE, Wilson PW, Peyser PA, Munroe PB, de Vries PS, Gauderman WJ, Sun YV, Chen H, Miller CL, Winkler TW, Rao DC, Redline S, van Heemst D | 2024-09-04 | medRxiv : the preprint server for health sciences | |
Late reproduction is associated with extended female survival but not with familial longevity. | de Kat AC, Roelofs F, Slagboom PE, Broekmans FJM, Beekman M, Berg NVD | 2024-09-01 | Ageing, Fertility, Longevity | Reproductive biomedicine online |
The contribution of suicide to maternal mortality: A nationwide population-based cohort study. | Lommerse KM, Mérelle S, Rietveld AL, Berkelmans G, van den Akker T | 2024-09-01 | maternal mortality, pregnancy‐related mortality, suicide, underreporting | BJOG : an international journal of obstetrics and gynaecology |
Prophylactic Radiologic Interventions for Postpartum Hemorrhage Control in Women With Placenta Accreta Spectrum Disorder: A Systematic Review and Meta-analysis. | Bonsen LR, Sleijpen K, Hendriks J, Urlings TAJ, Dekkers OM, le Cessie S, van de Velde M, Gurung P, van den Akker T, van der Bom JG, Henriquez DDCA | 2024-09-01 | Obstetrics and gynecology | |
Influence of arterial transit time delays on the differentiation between tumor progression and pseudoprogression in glioblastoma by arterial spin labeling magnetic resonance imaging. | van Dorth D, Jiang FY, Schmitz-Abecassis B, Croese RJI, Taphoorn MJB, Smits M, Koekkoek JAF, Dirven L, de Bresser J, van Osch MJP | 2024-09-01 | arterial spin labeling, arterial transit time, glioblastoma, perfusion MRI, pseudoprogression, tumor progression | NMR in biomedicine |
Prevalence and 3-month follow-up of cerebrovascular MRI markers in hospitalized COVID-19 patients: the CORONIS study. | van Lith TJ, Sluis WM, Wijers NT, Meijer FJA, Ulzen KK, de Bresser J, Dankbaar JW, de Mast Q, Klok FA, Cannegieter SC, Wermer MJH, Huisman MV, Tuladhar AM, van der Worp HB, de Leeuw FE | 2024-09-01 | Brain ischemia, COVID-19, Cerebrovascular disorders, MRI, SARS-CoV-2, WMH | Neuroradiology |
Genome-Wide Interaction Analyses of Serum Calcium on Ventricular Repolarization Time in 125 393 Participants. | Young WJ, van der Most PJ, Bartz TM, Bos MM, Biino G, Duong T, Foco L, Lominchar JT, Müller-Nurasyid M, Nardone GG, Pecori A, Ramirez J, Repetto L, Schramm K, Shen X, van Duijvenboden S, van Heemst D, Weiss S, Yao J, Benjamins JW, Alonso A, Spedicati B, Biggs ML, Brody JA, Dörr M, Fuchsberger C, Gögele M, Guo X, Ikram MA, Jukema JW, Kääb S, Kanters JK, Lin HJ, Linneberg A, Nauck M, Nolte IM, Pianigiani G, Santin A, Soliman EZ, Tesolin P, Vaccargiu S, Waldenberger M, van der Harst P, Verweij N, Arking DE, Concas MP, De Grandi A, Girotto G, Grarup N, Kavousi M, Mook-Kanamori DO, Navarro P, Orini M, Padmanabhan S, Pattaro C, Peters A, Pirastu M, Pramstaller PP, Heckbert SR, Sinner M, Snieder H, Völker U, Wilson JF, Gauderman WJ, Lambiase PD, Sotoodehnia N, Tinker A, Warren HR, Noordam R, Munroe PB | 2024-08-29 | ECG intervals, calcium, gene‐lifestyle interaction, genome‐wide association study, ventricular repolarization | Journal of the American Heart Association |
Temporalities of oxytocin for labour augmentation: a mixed-methods study of time factors shaping labour practices in a busy maternity unit in Tanzania. | Kujabi ML, Maembe L, Nkungu D, Maaløe N, D'mello BS, van Roosmalen J, van den Akker T, Konradsen F, Hussein K, Pallangyo E, Skovdal M, Sørensen JB | 2024-08-29 | Augmentation, Guidelines, Intrapartum, Low-resource, Oxytocin, PartoMa, Partograph, Prolonged labour, Time-pressure, Urbanisation | BMC pregnancy and childbirth |
NMR metabolomics-guided DNA methylation mortality predictors. | Bizzarri D, Reinders MJT, Kuiper L, Beekman M, Deelen J, van Meurs JBJ, van Dongen J, Pool R, Boomsma DI, Ghanbari M, Franke L, Slagboom PE, van den Akker EB | 2024-08-17 | Ageing biomarkers, DNA methylation predictors, Epidemiology, Epigenetic clock, Metabolic risk score, NMR metabolomics | EBioMedicine |
Secondary integrated analysis of multi-tissue transcriptomic responses to a combined lifestyle intervention in older adults from the GOTO nonrandomized trial | Bogaards FA, Gehrmann T, Beekman M, Lakenberg N, Suchiman HED, de Groot CPGM, Reinders MJT, Slagboom PE | 2024-08-15 | Nature Communications | |
DOSAGE study: protocol for a phase III non-inferiority randomised trial investigating dose-reduced chemotherapy for advanced colorectal cancer in older patients. | Baltussen JC, van den Bos F, Slingerland M, Binda TRR, Liefers GJ, van den Hout WB, Fiocco M, Verschoor AJ, Cloos-van Balen M, Holterhues C, Houtsma D, Jochems A, Spierings LEAMM, van Bodegom-Vos L, Mooijaart SP, Gelderblom H, Speetjens FM, de Glas NA, Portielje JEA | 2024-08-13 | CHEMOTHERAPY, GERIATRIC MEDICINE, Gastrointestinal tumours, ONCOLOGY, Quality of Life, Randomized Controlled Trial | BMJ open |
Post-COVID-19 recovery and geriatric rehabilitation care: a European inter-country comparative study. | van Tol LS, Lin T, Caljouw MAA, Cesari M, Dockery F, Everink IHJ, Francis BN, Gordon AL, Grund S, Matchekhina L, Bazan LMP, Topinková E, Vassallo MA, Achterberg WP, Haaksma ML | 2024-08-13 | COVID-19, Europe, Geriatric rehabilitation, Recovery | European geriatric medicine |
Allocation and value of curative oncological treatment in frail and fit older patients with esophageal cancer: An observational cohort study. | van der Poort EKJ, van Holstein Y, Slingerland M, Trompet S, van den Bos F, Portielje JEA, Steyerberg EW, van den Akker-van Marle ME, Bos WJW, Mooijaart SP, van den Hout WB | 2024-08-12 | Esophageal cancer, Frailty, Hospital costs, Patient-relevant outcomes, Value-based health care | Journal of geriatric oncology |
White matter hyperintensity shape is related to long-term progression of cerebrovascular disease in community-dwelling older adults. | Kuhn-Keller JA, Sigurdsson S, Launer LJ, van Buchem MA, van Osch MJ, Gudnason V, de Bresser J | 2024-08-07 | Cerebral small vessel disease, cerebrovascular disease, magnetic resonance imaging, vascular cognitive impairment, white matter hyperintensities | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism |
The association of inflammatory markers with frailty and in-hospital mortality in older COVID-19 patients. | Tran Van Hoi E, Appelman B, Mooijaart S, Dalm VASH, Polinder Bos HA, van Heemst D, van Raaij BFM, Noordam R, Kuranova A, Hoogerwerf JJ, Peeters G, Smorenberg A | 2024-08-06 | Ageing, COVID-19, Frailty, Immunosenescence, Inflammation | Experimental gerontology |
Older adults exercising ON TIME: protocol for a randomized controlled cross-over study to assess the effect of physical activity timing on insomnia severity. | Albalak G, Noordam R, van der Elst M, Kervezee L, Exadaktylos V, van Bodegom D, van Heemst D | 2024-08-05 | Biological clock, Crossover randomized controlled trial, Exercise, Physical activity, Sleep, Timing, Zeitgeber | Trials |
Phenotype prediction using biologically interpretable neural networks on multi-cohort multi-omics data. | van Hilten A, van Rooij J, Ikram MA, Niessen WJ, van Meurs JBJ, Roshchupkin GV | 2024-08-02 | NPJ systems biology and applications | |
Intrapartum antibiotic prophylaxis to prevent Group B streptococcal infections in newborn infants: a systematic review and meta-analysis comparing various strategies. | Panneflek TJR, Hasperhoven GF, Chimwaza Y, Allen C, Lavin T, Te Pas AB, Bekker V, van den Akker T | 2024-08-01 | Antibiotic prophylaxis, Early-onset neonatal sepsis, Group B streptococcus, Newborn infant, Risk-based, Screening | EClinicalMedicine |
Physical activity and fiber intake beneficial for muscle mass and strength preservation during aging: A comprehensive cross-sectional study in the UK biobank cohort. | Morwani-Mangnani J, Rodriguez-Girondo M, Singh-Povel C, Verlaan S, Beekman M, Slagboom PE | 2024-08-01 | Biology of aging, Healthy aging, Lifestyle, Muscle health, Nutrition, UK biobank, fiber intake | Experimental gerontology |
Inconsistent definitions of prolonged labor in international literature: a scoping review. | Bakker W, Sandberg EM, Keetels S, Schoones JW, Kujabi ML, Maaløe N, Maswime S, van den Akker T | 2024-08-01 | active support of labor, definition, labor dystocia, labor management, labor progress, partograph, prolonged first stage of labor, prolonged second stage of labor | AJOG global reports |
The Impact of Delirium on Recovery in Geriatric Rehabilitation after Acute Infection. | Minnema J, Polinder-Bos HA, Cesari M, Dockery F, Everink IHJ, Francis BN, Gordon AL, Grund S, Perez Bazan LM, Eruslanova K, Topinková E, Vassallo MA, Faes MC, van Tol LS, Caljouw MAA, Achterberg WP, Haaksma ML | 2024-08-01 | ADL, COVID-19, Delirium, Geriatric rehabilitation, Older adults, QoL, Recovery | Journal of the American Medical Directors Association |
Service provision for Frailty in European Emergency Departments (FEED): a survey of operational characteristics. | Fehlmann CA, Mc Loughlin K, Cosgriff EJ, Ferrick JF, van Oppen JD | 2024-07-29 | Delirium, Emergency care, Frailty, Health services | Scandinavian journal of trauma, resuscitation and emergency medicine |
Person-centred decisions in emergency care for older people living with frailty: principles and practice. | van Oppen JD, Coats T, Conroy S, Hayden S, Heeren P, Hullick C, Liu S, Lucke J, Lukin B, McNamara R, Melady D, Mooijaart SP, Rosen T, Banerjee J | 2024-07-26 | emergency departments, ethics, frailty, geriatrics | Emergency medicine journal : EMJ |
Effect of COVID-19 lockdown on maternity care and maternal outcome in the Netherlands: a national quasi-experimental study. | Gravesteijn BY, Boderie NW, van den Akker T, Bertens LCM, Bloemenkamp K, Burgos Ochoa L, de Jonge A, Kazemier BM, Klein PPF, Kwint-Reijnders I, Labrecque JA, Mol BW, Obermann-Borst SA, Peters L, Ravelli ACJ, Rosman A, Been JV, de Groot CJ | 2024-07-20 | COVID-19, Homebirth, Maternal health, Natural experiment, SARS-CoV−2 | Public health |
Association between bilirubin and biomarkers of metabolic health and oxidative stress in the MARK-AGE cohort. | Schoissengeier V, Maqboul L, Weber D, Grune T, Bürkle A, Moreno-Villaneuva M, Franceschi C, Capri M, Bernhard J, Toussaint O, Debacq-Chainiaux F, Weinberger B, Gonos ES, Sikora E, Dollé M, Jansen E, Slagboom PE, Hervonnen A, Hurme M, Breusing N, Frank J, Bulmer AC, Wagner KH | 2024-07-19 | human metabolism, pathology, public health | iScience |
Time to redefine prolonged third stage of labor? A systematic review and meta-analysis of the length of the third stage of labor and adverse maternal outcome after vaginal birth. | de Vries PLM, Veenstra E, Baud D, Legardeur H, Kallianidis AF, van den Akker T | 2024-07-19 | adverse maternal outcome, manual removal of the placenta, postpartum hemorrhage, third stage of labor, timing | American journal of obstetrics and gynecology |
A Large-Scale Genome-Wide Study of Gene-Sleep Duration Interactions for Blood Pressure in 811,405 Individuals from Diverse Populations. | Wang H, Nagarajan P, Winkler T, Bentley A, Miller C, Kraja A, Schwander K, Lee S, Wang W, Brown M, Morrison J, Giri A, O'Connell J, Bartz T, de Las Fuentes L, Gudmundsdottir V, Guo X, Harris S, Huang Z, Kals M, Kho M, Lefevre C, Luan J, Lyytikäinen LP, Mangino M, Milaneschi Y, Palmer N, Rao V, Rauramaa R, Shen B, Stadler S, Sun Q, Tang J, Thériault S, van der Graaf A, van der Most P, Wang Y, Weiss S, Westerman K, Yang Q, Yasuharu T, Zhao W, Zhu W, Altschul D, Ansari MAY, Anugu P, Argoty-Pantoja A, Arzt M, Aschard H, Attia J, Bazzano L, Breyer M, Brody J, Cade B, Chen HH, Chen YI, Chen Z, de Vries P, Dimitrov L, Do A, Du J, Dupont C, Edwards T, Evans M, Faquih T, Felix S, Fisher-Hoch S, Floyd J, Graff M, Charles Gu C, Gu D, Hairston K, Hanley A, Heid I, Heikkinen S, Highland H, Hood M, Kähönen M, Karvonen-Gutierrez C, Kawaguchi T, Kazuya S, Tanika K, Komulainen P, Levy D, Lin H, Liu P, Marques-Vidal P, McCormick J, Mei H, Meigs J, Menni C, Nam K, Nolte I, Pacheco N, Petty L, Polikowsky H, Province M, Psaty B, Raffield L, Raitakari O, Rich S, Riha R, Risch L, Risch M, Ruiz-Narvaez E, Scott R, Sitlani C, Smith J, Sofer T, Teder-Laving M, Völker U, Vollenweider P, Wang G, van Dijk KW, Wilson O, Xia R, Yao J, Young K, Zhang R, Zhu X, Below J, Böger C, Conen D, Cox S, Dörr M, Feitosa M, Fox E, Franceschini N, Gharib S, Gudnason V, Harlow S, He J, Holliday E, Kutalik Z, Lakka T, Lawlor D, Lee S, Lehtimäki T, Li C, Liu CT, Mägi R, Matsuda F, Morrison A, Penninx BWJH, Peyser P, Rotter J, Snieder H, Spector T, Wagenknecht L, Wareham N, Zonderman A, North K, Fornage M, Hung A, Manning A, Gauderman W, Chen H, Munroe P, Rao D, van Heemst D, Redline S, Noordam R | 2024-07-17 | Research square | |
Mind-body practices for people living with dementia and their family carers: a systematic review. | van der Ploeg ES, Bitane RM, Schoones JW, Achterberg WP, Smaling HJA | 2024-07-16 | dementia, dyads, family carers, mind-body practices, systematic review | Journal of complementary & integrative medicine |
The performance of metabolomics-based prediction scores for mortality in older patients with solid tumors. | van Holstein Y, Mooijaart SP, van Oevelen M, van Deudekom FJ, Vojinovic D, Bizzarri D, van den Akker EB, Noordam R, Deelen J, van Heemst D, de Glas NA, Holterhues C, Labots G, van den Bos F, Beekman M, Slagboom PE, van Munster BC, Portielje JEA, Trompet S | 2024-07-04 | Biomarkers, Geriatric assessment, Geriatric oncology, Metabolomics, Mortality | GeroScience |
Temporal dynamics of depressive symptoms and cognitive decline in the oldest old: dynamic time warp analysis of the Leiden 85-plus study. | van der Slot AJC, Bertens AS, Trompet S, Mooijaart SP, Gussekloo J, van den Bos F, Giltay EJ | 2024-07-02 | cognitive impairment, depression, network analysis, older people, oldest old, time series | Age and ageing |
Effects of the discontinuation of antihypertensive treatment on neuropsychiatric symptoms and quality of life in nursing home residents with dementia (DANTON): a multicentre, open-label, blinded-outcome, randomised controlled trial. | Bogaerts JMK, Gussekloo J, de Jong-Schmit BEM, Le Cessie S, Mooijaart SP, van der Mast RC, Achterberg WP, Poortvliet RKE | 2024-07-02 | antihypertensive treatment, dementia, deprescribing, hypertension, older people, randomised controlled trial | Age and ageing |
Tolerability and effectiveness of palbociclib in older women with metastatic breast cancer. | Baltussen JC, Mooijaart SP, Vulink AJE, Houtsma D, Van der Deure WM, Westerman EM, Oosterkamp HM, Spierings LEAMM, van den Bos F, de Glas NA, Portielje JEA | 2024-07-01 | Metastatic breast cancer, Older patients, Palbociclib, Real-world data, Tolerability, Toxicity | Breast cancer research and treatment |
Professional identity formation of medical students in relation to the care of older persons: a review of the literature. | Moll-Jongerius A, Langeveld K, Tong W, Masud T, Kramer AWM, Achterberg WP | 2024-07-01 | Professional identity formation, geriatrics, medical students, older persons, undergraduate medical education | Gerontology & geriatrics education |
SMIM1 absence is associated with reduced energy expenditure and excess weight. | Stefanucci L, Moslemi C, Tomé AR, Virtue S, Bidault G, Gleadall NS, Watson LPE, Kwa JE, Burden F, Farrow S, Chen J, Võsa U, Burling K, Walker L, Ord J, Barker P, Warner J, Frary A, Renhstrom K, Ashford SE, Piper J, Biggs G, Erber WN, Hoffman GJ, Schoenmakers N, Erikstrup C, Rieneck K, Dziegiel MH, Ullum H, Azzu V, Vacca M, Aparicio HJ, Hui Q, Cho K, Sun YV, Wilson PW, Bayraktar OA, Vidal-Puig A, Ostrowski SR, Astle WJ, Olsson ML, Storry JR, Pedersen OB, Ouwehand WH, Chatterjee K, Vuckovic D, Frontini M | 2024-06-17 | BMI, SMIM1, Translation to patients, Vel, blood groups, dyslipidemia, metabolism, obesity, population genetics, weight | Med (New York, N.Y.) |
Prevalence and burden of pain across the entire spectrum of Huntington’s disease. | Sprenger GP, van Zwet EW, Bakels HS, Achterberg WP, Roos RA, de Bot ST | 2024-06-17 | MOVEMENT DISORDERS, PAIN | Journal of neurology, neurosurgery, and psychiatry |
Orthostatic hypotension, cognition and structural brain imaging in hemodynamically impaired patients. | Starmans NLP, Wolters FJ, Leeuwis AE, Bron EE, de Bresser J, Brunner-La Rocca HP, Staals J, Muller M, Biessels GJ, Kappelle LJ | 2024-06-15 | Atrophy, Blood pressure, Cerebral small vessel disease, Cognition, Orthostatic hypotension, White matter hyperintensities | Journal of the neurological sciences |
Differences in characteristics and outcomes of older patients hospitalized for COVID-19 after introduction of vaccination. | Smits RAL, van Raaij BFM, Trompet S, van der Linden CMJ, van der Bol JM, Jansen SWM, Polinder-Bos HA, Willems HC, van de Glind EMM, Minnema J, Tap L, Mooijaart SP | 2024-06-11 | COVID-19, Frailty, In-hospital mortality, Older patient, Vaccination | European geriatric medicine |
Preparing for future pandemics: frailty associates with mortality in hospitalised older people during the entire COVID-19 pandemic, a Dutch multicentre cohort study. | van Raaij BFM, Noordam R, Smits RAL, van der Klei VMGTH, Jansen SWM, van der Linden CMJ, Polinder-Bos HA, Minnema J, Tap L, van der Bol JM, van de Glind EMM, Willems HC, van Deudekom FJA, Ruiter R, van Munster BC, Robben SHM, Schouten HJ, Barten DG, Lucke JA, Peeters G, Trompet S, Drewes YM, van den Bos F, Gussekloo J, Mooijaart SP | 2024-06-07 | COVID-19, Frailty, In-hospital mortality | European geriatric medicine |
A plant-based diet index to study the relation between diet and disease risk among adults: a narrative review. | Schorr KA, Agayn V, de Groot LCPGM, Slagboom PE, Beekman M | 2024-06-01 | Age-related diseases, Cardiovascular disease, Nutritional epidemiology, Plant-based diet, Type 2 diabetes | The journal of nutrition, health & aging |
Unraveling interindividual variation of trimethylamine N-oxide and its precursors at the population level. | Andreu-Sánchez S, Ahmad S, Kurilshikov A, Beekman M, Ghanbari M, van Faassen M, van den Munckhof ICL, Steur M, Harms A, Hankemeier T, Ikram MA, Kavousi M, Voortman T, Kraaij R, Netea MG, Rutten JHW, Riksen NP, Zhernakova A, Kuipers F, Slagboom PE, van Duijn CM, Fu J, Vojinovic D | 2024-06-01 | TMAO, diet, genetics, gut microbiome, meta‐analysis, population cohort | iMeta |
No evidence linking sleep traits with white blood cell counts: Multivariable-adjusted and Mendelian randomization analyses. | Noordam R, Ao L, Stroo JF, Willems van Dijk K, van Heemst D | 2024-06-01 | Mendelian randomization, sleep, white blood cells | European journal of clinical investigation |
Variations over time in mode of birth and perinatal outcomes in women with one previous cesarean in the Netherlands: A 20-year population-based study. | Koorn I, Vis LC, Verschueren KJC, Rosman AN, van den Akker T | 2024-06-01 | cesarean birth, obstetrics, vaginal birth after cesarean | Birth (Berkeley, Calif.) |
The influence of chorioamnionitis on respiratory drive and spontaneous breathing of premature infants at birth: a narrative review. | Panneflek TJR, Kuypers KLAM, Polglase GR, Derleth DP, Dekker J, Hooper SB, van den Akker T, Pas ABT | 2024-06-01 | Breathing, Chorioamnionitis, Inflammation, Neonatology, Resuscitation | European journal of pediatrics |
Nephrology-tailored geriatric assessment as decision-making tool in kidney failure. | Berkhout-Byrne NC, Voorend CGN, Meuleman Y, Mooijaart SP, Brunsveld-Reinders AH, Bos WJW, Van Buren M | 2024-06-01 | geriatric assessment, kidney failure, kidney replacement therapy, older patients, shared decision‐making | Journal of renal care |
Patient-Reported Satisfaction with Thyroid Hormone Replacement Therapy for Subclinical Hypothyroidism in Older Adults: A Pooled Analysis of Individual Participant Data from Two Randomized Controlled Trials. | Ravensberg J, Poortvliet RKE, Du Puy R, Rodondi N, Blum M, Kearney P, McCarthy VJC, Quinn T, Dekkers O, Jukema W, Mooijaart S, Gussekloo J | 2024-06-01 | aged, humans, patient satisfaction, randomized controlled trial, subclinical hypothyroidism, thyroxine | Thyroid : official journal of the American Thyroid Association |
[Not Available]. | Van Asbroeck S, Köhler S, van Boxtel MPJ, Lipnicki DM, Crawford JD, Castro-Costa E, Lima-Costa MF, Blay SL, Shifu X, Wang T, Yue L, Lipton RB, Katz MJ, Derby CA, Guerchet M, Preux PM, Mbelesso P, Norton J, Ritchie K, Skoog I, Najar J, Sterner TR, Scarmeas N, Yannakoulia M, Dardiotis T, Rolandi E, Davin A, Rossi M, Gureje O, Ojagbemi A, Bello T, Kim KW, Han JW, Oh DJ, Trompet S, Gussekloo J, Riedel-Heller SG, Röhr S, Pabst A, Shahar S, Rivan NFM, Singh DKA, Jacobsen E, Ganguli M, Hughes T, Haan M, Aiello AE, Ding D, Zhao Q, Xiao Z, Narazaki K, Chen T, Chen S, Ng TP, Gwee X, Gao Q, Brodaty H, Trollor J, Kochan N, Lobo A, Santabárbara J, Gracia-Garcia P, Sachdev PS, Deckers K | 2024-06-01 | age, dementia, dementia risk reduction, education, effect modification, ethnicity, individual participant data meta‐analysis, interaction, lifestyle, primary prevention, region, risk factor, risk personalization, sex, socioeconomic | Alzheimer's & dementia : the journal of the Alzheimer's Association |
A systematic review of subclinical hyperthyroidism guidelines: a remarkable range of recommendations. | Ursem SR, Boelen A, Bruinstroop E, Elders PJM, Gussekloo J, Poortvliet RKE, Heijboer AC, den Elzen WPJ | 2024-06-01 | clinical practice guideline, general practice, guideline, primary care, subclinical hyperthyroidism, systematic review, thyroid | European thyroid journal |
Movement Patterns in Older Adults Recovering From Hip Fracture. | Kraaijkamp JJM, Stijntjes M, De Groot JH, Chavannes NH, Achterberg WP, van Dam van Isselt EF | 2024-06-01 | accelerometer, geriatric rehabilitation, sedentary behavior | Journal of aging and physical activity |
Implementation of an Advance Care Planning Intervention in Nursing Homes: An International Multiple Case Study. | Brazil K, Walshe C, Doherty J, Harding AJE, Preston N, Bavelaar L, Cornally N, Di Giulio P, Gonella S, Hartigan I, Henderson C, Kaasalainen S, Loucka M, Sussman T, Vlckova K, van der Steen JT | 2024-06-01 | Comfort care, Decision-making, Dementia, Family caregiver | The Gerontologist |
Is CAA a perivascular brain clearance disease? A discussion of the evidence to date and outlook for future studies. | van Veluw SJ, Benveniste H, Bakker ENTP, Carare RO, Greenberg SM, Iliff JJ, Lorthois S, Van Nostrand WE, Petzold GC, Shih AY, van Osch MJP | 2024-05-27 | Brain clearance, Cerebral amyloid angiopathy, Cerebrospinal fluid, Glymphatics, IPAD, Perivascular spaces | Cellular and molecular life sciences : CMLS |
Does higher performance in a national licensing examination predict better quality of care? A longitudinal observational study of Ethiopian anesthetists. | Asemu YM, Yigzaw T, Desta FA, Scheele F, van den Akker T | 2024-05-27 | Anesthetists, Associate clinicians, Licensing examination, Patient outcome, Quality of care | BMC anesthesiology |
Maternal thyroid function in early pregnancy and offspring school performance and neurodevelopmental disorders. | Møllehave LT, Grand MK, Kriegbaum M, Andersen CL, Lind BS, van Vliet NA, van Heemst D, Strandberg-Larsen K | 2024-05-24 | attention deficit hyperactivity disorder, autism spectrum disorder, neurodevelopment, pregnancy, thyroid function | The Journal of clinical endocrinology and metabolism |
Author Correction: Prospective individual patient data meta-analysis of two randomized trials on convalescent plasma for COVID-19 outpatients. | Millat-Martinez P, Gharbharan A, Alemany A, Rokx C, Geurtsvankessel C, Papageorgiou G, van Geloven N, Jordans C, Groeneveld G, Swaneveld F, van der Schoot E, Corbacho-Monné M, Ouchi D, Piccolo Ferreira F, Malchair P, Videla S, García García V, Ruiz-Comellas A, Ramírez-Morros A, Rodriguez Codina J, Amado Simon R, Grifols JR, Blanco J, Blanco I, Ara J, Bassat Q, Clotet B, Baro B, Troxel A, Zwaginga JJ, Mitjà O, Rijnders BJA | 2024-05-22 | Nature communications | |
Plasma trimethylamine N-oxide (TMAO): associations with cognition, neuroimaging, and dementia. | Yaqub A, Vojinovic D, Vernooij MW, Slagboom PE, Ghanbari M, Beekman M, van der Grond J, Hankemeier T, van Duijn CM, Ikram MA, Ahmad S | 2024-05-20 | Cognition, Dementia, Gut-microbiome, Metabolites, Neuroimaging, Population-based | Alzheimer's research & therapy |
Knee-to-chest flexion manoeuvre to reduce respiratory distress after planned caesarean birth: a feasibility study. | Shirima FL, Keus A, Mmbaga BT, Hooper SB, Mchome B, Pyuza JJ, Van Den Akker T, Te Pas AB | 2024-05-06 | Neonatology, Respiratory Medicine | Archives of disease in childhood. Fetal and neonatal edition |
Determinants of behaviors influencing implementation of maternal and perinatal death surveillance and response in low- and middle-income countries: A systematic review of qualitative studies. | Willcox ML, Okello IA, Maidwell-Smith A, Tura AK, van den Akker T, Knight M, Dumont A, Muller I | 2024-05-01 | behavioral factors, implementation, intervention planning, low‐ and middle‐income countries, maternal and perinatal death surveillance and review (MPDSR), qualitative, systematic review | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics |
Efficacy and Safety Analyses of Recombinant Factor VIIa in Severe Post-Partum Hemorrhage. | Caram-Deelder C, McKinnon Edwards H, Zdanowicz JA, van den Akker T, Birkegård C, Blatný J, van der Bom JG, Colucci G, van Duuren D, van Geloven N, Henriquez DDCA, Knight M, Korsholm L, Landorph A, Lavigne Lissalde G, McQuilten ZK, Surbek D, Wellard C, Wood EM, Mercier FJ | 2024-05-01 | coagulants, delivery, hematologic, maternal mortality, obstetric, post-partum hemorrhage, pregnancy complications, recombinant activated factor VII, therapeutic use, thromboembolic events | Journal of clinical medicine |
Geriatric Assessment in CKD Care: An Implementation Study. | Voorend CGN, Berkhout-Byrne NC, van Bodegom-Vos L, Diepenbroek A, Franssen CFM, Joosten H, Mooijaart SP, Bos WJW, van Buren M | 2024-05-01 | Chronic kidney disease, feasibility studies, geriatric assessment, implementation science, older people, shared decision making | Kidney medicine |
Toxicity in Older Patients with Cancer Receiving Immunotherapy: An Observational Study. | Tran Van Hoi E, Trompet S, Van Holstein Y, Van Den Bos F, Van Heemst D, Codrington H, Labots G, Lohman S, Ozkan A, Portielje J, Mooijaart SP, De Glas NA, Derks M | 2024-05-01 | Drugs & aging | |
Older people’s goals of care in relation to frailty status-the COOP-study. | van der Klei VMGTH, Drewes YM, van Raaij BFM, van Dalsen MDW, Julien AG, Festen J, Polinder-Bos H, Mooijaart SP, Gussekloo J, van den Bos F | 2024-05-01 | decision-making, health outcome prioritisation, older people, patient and public involvement, patient preference | Age and ageing |
Sporadic cerebral small vessel disease and cognitive decline in healthy older adults: A systematic review and meta-analysis. | Jansma A, de Bresser J, Schoones JW, van Heemst D, Akintola AA | 2024-05-01 | Cognitive decline, MRI, cerebral small vessel disease, meta-analysis, older adults | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism |
Impact of Pain and Neuropsychiatric Symptoms on Activities in Nursing Home Residents (COSMOS Trial). | van de Beek SH, Erdal A, Husebø BS, Vislapuu M, Achterberg WP, Caljouw MAA | 2024-05-01 | COSMOS study, Dementia, activity, behavior, nursing homes, pain | Journal of the American Medical Directors Association |
Post-COVID-19 patients in geriatric rehabilitation substantially recover in daily functioning and quality of life. | van Tol LS, Haaksma ML, Cesari M, Dockery F, Everink IHJ, Francis BN, Gordon AL, Grund S, Matchekhina L, Bazan LMP, Schols JMGA, Topinková E, Vassallo MA, Caljouw MAA, Achterberg WP | 2024-05-01 | COVID-19, geriatric rehabilitation, older people, recovery | Age and ageing |
Relocating within and between nursing homes during infectious disease outbreaks: A focus group study. | Broekharst DSE, Stoop A, Caljouw MAA, Achterberg WP | 2024-05-01 | COVID‐19, epidemics, infectious disease outbreaks, pandemics, relocations | Health science reports |
Frailty Screening is Associated with Hospitalization and Decline in Quality of Life and Functional Status in Older Patients with Inflammatory Bowel Disease. | Asscher VER, Rodriguez Gírondo M, Fens J, Waars SN, Stuyt RJL, Baven-Pronk AMC, Srivastava N, Jacobs RJ, Haans JJL, Meijer LJ, Klijnsma-Slagboom JD, Duin MH, Peters MER, Lee-Kong FVYL, Provoost NE, Tijdeman F, van Dijk KT, Wieland MWM, Verstegen MGM, van der Meijs ME, Maan ADI, van Deudekom FJ, van der Meulen-de Jong AE, Mooijaart SP, Maljaars PWJ | 2024-04-23 | Crohn’s disease, elderly, functional decline, geriatric screening, ulcerative colitis | Journal of Crohn's & colitis |
Active involvement in scientific research of persons living with dementia and long-term care users: a systematic review of existing methods with a specific focus on good practices, facilitators and barriers of involvement. | Groothuijse JM, van Tol LS, Leeuwen CCMTH, van Delden JJM, Caljouw MAA, Achterberg WP | 2024-04-09 | Dementia, Involvement in research, Long-term care, Methods, Older residents, Review | BMC geriatrics |
Identification of Distinct Brain MRI Phenotypes and Their Association With Long-Term Dementia Risk in Community-Dwelling Older Adults | Keller JA, Sigurdsson S, Schmitz Abecassis B, Kant IM, Van Buchem MA, Launer LJ, van Osch MJ, Gudnason V, de Bresser J | 2024-04-09 | Neurology | |
Associations of circulating GDF15 with combined cognitive frailty and depression in older adults of the MARK-AGE study. | Kochlik B, Herpich C, Moreno-Villanueva M, Klaus S, Müller-Werdan U, Weinberger B, Fiegl S, Toussaint O, Debacq-Chainiaux F, Schön C, Bernhard J, Breusing N, Gonos ES, Franceschi C, Capri M, Sikora E, Hervonen A, Hurme M, Slagboom PE, Dollé MET, Jansen E, Grune T, Bürkle A, Norman K | 2024-04-01 | Aging, Biomarker, Cognitive frailty, Depression, GDF15 | GeroScience |
Genome-wide characterization of circulating metabolic biomarkers. | Karjalainen MK, Karthikeyan S, Oliver-Williams C, Sliz E, Allara E, Fung WT, Surendran P, Zhang W, Jousilahti P, Kristiansson K, Salomaa V, Goodwin M, Hughes DA, Boehnke M, Fernandes Silva L, Yin X, Mahajan A, Neville MJ, van Zuydam NR, de Mutsert R, Li-Gao R, Mook-Kanamori DO, Demirkan A, Liu J, Noordam R, Trompet S, Chen Z, Kartsonaki C, Li L, Lin K, Hagenbeek FA, Hottenga JJ, Pool R, Ikram MA, van Meurs J, Haller T, Milaneschi Y, Kähönen M, Mishra PP, Joshi PK, Macdonald-Dunlop E, Mangino M, Zierer J, Acar IE, Hoyng CB, Lechanteur YTE, Franke L, Kurilshikov A, Zhernakova A, Beekman M, van den Akker EB, Kolcic I, Polasek O, Rudan I, Gieger C, Waldenberger M, Asselbergs FW, Hayward C, Fu J, den Hollander AI, Menni C, Spector TD, Wilson JF, Lehtimäki T, Raitakari OT, Penninx BWJH, Esko T, Walters RG, Jukema JW, Sattar N, Ghanbari M, Willems van Dijk K, Karpe F, McCarthy MI, Laakso M, Järvelin MR, Timpson NJ, Perola M, Kooner JS, Chambers JC, van Duijn C, Slagboom PE, Boomsma DI, Danesh J, Ala-Korpela M, Butterworth AS, Kettunen J | 2024-04-01 | Nature | |
Approaches to improve and adapt maternal mortality estimations in low- and middle-income countries: A scoping review. | Tholandi M, Zethof S, Kim YM, Tura AK, Ket J, Willcox M, van den Akker T, Ilozumba O | 2024-04-01 | community participation, data collection, developing countries, maternal death, maternal mortality, quality indicators | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics |
Severe postpartum hemorrhage and the risk of adverse maternal outcome: A comparative analysis of two population-based studies in France and the Netherlands. | de Vries PLM, Deneux-Tharaux C, Caram-Deelder C, Goffinet F, Henriquez DDCA, Seco A, van der Bom JG, van den Akker T | 2024-04-01 | Clinical care, Cross-country studies, Management, Maternal morbidity, Maternal mortality, Obstetric hemorrhage, Severe maternal outcome | Preventive medicine reports |
Prevalence of Frailty in European Emergency Departments (FEED): an international flash mob study. | 2024-04-01 | Emergency care, Frailty, Geriatrics | European geriatric medicine | |
Older patients’ experiences with and attitudes towards an oncogeriatric pathway: A qualitative study. | Uit den Boogaard A, de Jongh D, van den Elst MJT, Trompet S, de Man-van Ginkel JM, Portielje JEA, Meuleman Y, Mooijaart SP, de Glas NA, van den Bos F | 2024-04-01 | Geriatric assessment, Geriatric oncology, Oncogeriatric care pathway, Patient experiences, Qualitative study | Journal of geriatric oncology |
External validation of six COVID-19 prognostic models for predicting mortality risk in older populations in a hospital, primary care, and nursing home setting. | Zahra A, van Smeden M, Abbink EJ, van den Berg JM, Blom MT, van den Dries CJ, Gussekloo J, Wouters F, Joling KJ, Melis R, Mooijaart SP, Peters JB, Polinder-Bos HA, van Raaij BFM, Appelman B, la Roi-Teeuw HM, Moons KGM, Luijken K | 2024-04-01 | COVID-19, COVID-19-Related mortality, External validation, Older population, Prognostic models, clinical prediction models | Journal of clinical epidemiology |
Structural disconnectivity in postoperative delirium: A perioperative two-center cohort study in older patients. | Fislage M, Winzeck S, Woodrow R, Lammers-Lietz F, Stamatakis EA, Correia MM, Preller J, Feinkohl I, Hendrikse J, Pischon T, Spies CD, Slooter AJC, Winterer G, Menon DK, Zacharias N | 2024-04-01 | brain health, dementia delirium interface, diffusion kurtosis imaging, postoperative delirium, structural disconnectivity, white matter abnormalities | Alzheimer's & dementia : the journal of the Alzheimer's Association |
Future policy and research for advance care planning in dementia: consensus recommendations from an international Delphi panel of the European Association for Palliative Care | Nakanishi M, Martins Pereira S, Van den Block L, Parker D, Harrison-Dening K, Di Giulio P, In der Schmitten J, Larkin PJ, Mimica N, Sudore RL, Holmerová I, Korfage IJ, van der Steen JT | 2024-04-01 | The Lancet Healthy Longevity | |
The role of genetically-influenced phospholipid transfer protein activity in lipoprotein metabolism and coronary artery disease. | Ao L, Noordam R, Rensen PCN, van Heemst D, Willems van Dijk K | 2024-03-29 | Coronary artery disease, Genetic risk score, Lipoprotein metabolism, Phospholipid transfer protein (PLTP) activity | Journal of clinical lipidology |
The effect of paracetamol on care dependency and daily functioning in persons with advanced dementia living in long-term care facilities. | van Dam PH, Achterberg WP, Husebo BS, Caljouw MA | 2024-03-22 | Acetaminophen, Care dependency, Daily functioning, Dementia, Nursing home, Paracetamol, Quality of life | BMC geriatrics |
Healthcare worker burnout: exploring the experiences of doctors working in a maternity unit in Namibia. | Brückner TY, Heemelaar S, Endjala T, van den Akker T | 2024-03-21 | Blame culture, Burnout, Healthcare worker, Maternal health, Support, Trauma | BMC health services research |
Noninvasive monitoring technologies to identify discomfort and distressing symptoms in persons with limited communication at the end of life: a scoping review. | Xu J, Smaling HJA, Schoones JW, Achterberg WP, van der Steen JT | 2024-03-21 | Dementia, Information technology, Medical informatics, Palliative care | BMC palliative care |
Factors influencing interprofessional collaboration in general and during multidisciplinary team meetings in long-term care and geriatric rehabilitation: a qualitative study. | Doornebosch AJ, Achterberg WP, Smaling HJA | 2024-03-15 | Barriers, Facilitators, Geriatric rehabilitation, Interprofessional collaboration, Long-term care, Multidisciplinary team meetings, Patient outcome measures | BMC medical education |
Clarifying the biological and statistical assumptions of cross-sectional biological age predictors: an elaborate illustration using synthetic and real data. | Sluiskes MH, Goeman JJ, Beekman M, Slagboom PE, Putter H, Rodríguez-Girondo M | 2024-03-08 | Aging, Aging clocks, Aging divergence, Aging rate, Biological age, Cross-sectional biological age predictors, Klemera-Doubal | BMC medical research methodology |
A Large-Scale Genome-Wide Study of Gene-Sleep Duration Interactions for Blood Pressure in 811,405 Individuals from Diverse Populations. | Nagarajan P, Winkler TW, Bentley AR, Miller CL, Kraja AT, Schwander K, Lee S, Wang W, Brown MR, Morrison JL, Giri A, O'Connell JR, Bartz TM, de Las Fuentes L, Gudmundsdottir V, Guo X, Harris SE, Huang Z, Kals M, Kho M, Lefevre C, Luan J, Lyytikäinen LP, Mangino M, Milaneschi Y, Palmer ND, Rao V, Rauramaa R, Shen B, Stadler S, Sun Q, Tang J, Thériault S, van der Graaf A, van der Most PJ, Wang Y, Weiss S, Westerman KE, Yang Q, Yasuharu T, Zhao W, Zhu W, Altschul D, Ansari MAY, Anugu P, Argoty-Pantoja AD, Arzt M, Aschard H, Attia JR, Bazzanno L, Breyer MA, Brody JA, Cade BE, Chen HH, Ida Chen YD, Chen Z, de Vries PS, Dimitrov LM, Do A, Du J, Dupont CT, Edwards TL, Evans MK, Faquih T, Felix SB, Fisher-Hoch SP, Floyd JS, Graff M, Gu C, Gu D, Hairston KG, Hanley AJ, Heid IM, Heikkinen S, Highland HM, Hood MM, Kähönen M, Karvonen-Gutierrez CA, Kawaguchi T, Kazuya S, Kelly TN, Komulainen P, Levy D, Lin HJ, Liu PY, Marques-Vidal P, McCormick JB, Mei H, Meigs JB, Menni C, Nam K, Nolte IM, Pacheco NL, Petty LE, Polikowsky HG, Province MA, Psaty BM, Raffield LM, Raitakari OT, Rich SS, Riha RL, Risch L, Risch M, Ruiz-Narvaez EA, Scott RJ, Sitlani CM, Smith JA, Sofer T, Teder-Laving M, Völker U, Vollenweider P, Wang G, van Dijk KW, Wilson OD, Xia R, Yao J, Young KL, Zhang R, Zhu X, Below JE, Böger CA, Conen D, Cox SR, Dörr M, Feitosa MF, Fox ER, Franceschini N, Gharib SA, Gudnason V, Harlow SD, He J, Holliday EG, Kutalik Z, Lakka TA, Lawlor DA, Lee S, Lehtimäki T, Li C, Liu CT, Mägi R, Matsuda F, Morrison AC, Penninx BW, Peyser PA, Rotter JI, Snieder H, Spector TD, Wagenknecht LE, Wareham NJ, Zonderman AB, North KE, Fornage M, Hung AM, Manning AK, Gauderman J, Chen H, Munroe PB, Rao DC, van Heemst D, Redline S, Noordam R, Wang H | 2024-03-08 | medRxiv : the preprint server for health sciences | |
Physiological-based cord clamping in very preterm infants: the Aeration, Breathing, Clamping 3 (ABC3) trial-statistical analysis plan for a multicenter randomized controlled trial. | Willemsen SP, Knol R, Brouwer E, van den Akker T, DeKoninck PLJ, Lopriore E, Onland W, de Boode WP, van Kaam AH, Nuytemans DH, Reiss IKM, Hutten GJ, Prins SA, Mulder EEM, Hulzebos CV, van Sambeeck SJ, van der Putten ME, Zonnenberg IA, Te Pas AB, Vermeulen MJ | 2024-03-04 | Cord clamping, Physiological-based cord clamping, Preterm infants, Randomized clinical trial, Statistical Analysis Plan | Trials |
Monoclonal RhD prophylaxis: high time to evaluate efficacy. | Verweij E, Tura AK, Gure T, Pyuza J, Mchome B, Kawaza K, Moons P, de Winter D, Van't Oever R, Spitalnik S, van der Schoot CE, van den Akker T | 2024-03-02 | Lancet (London, England) | |
The impact of the COVID-19 pandemic on Positive Health among older adults in relation to the complexity of health problems. | van der Klei VMGTH, Moens IS, Simons T, den Elzen WPJ, Mooijaart SP, Gussekloo J, Trompet S, Drewes YM | 2024-03-01 | COVID-19, community-dwelling, health impact assessment, older adults, self-rated health | Journal of the American Geriatrics Society |
Aetiology and use of antibiotics in pregnancy-related infections: results of the WHO Global Maternal Sepsis Study (GLOSS), 1-week inception cohort. | Ribeiro-do-Valle CC, Bonet M, Brizuela V, Abalos E, Baguiya A, Bellissimo-Rodrigues F, Budianu M, Puscasiu L, Knight M, Lissauer D, Dunlop C, Jacob ST, Shakoor S, Gadama L, Assarag B, Souza JP, Cecatti JG | 2024-02-24 | Antibiotic, Infections, Maternal morbidity, Maternal sepsis | Annals of clinical microbiology and antimicrobials |
Limited incremental predictive value of the frailty index and other vulnerability measures from routine care data for mortality risk prediction in older patients with COVID-19 in primary care. | la Roi-Teeuw HM, Luijken K, Blom MT, Gussekloo J, Mooijaart SP, Polinder-Bos HA, van Smeden M, Geersing GJ, van den Dries CJ | 2024-02-23 | COVID-19, Frailty, Multiple imputation, Older people, Primary care, Prognosis research, Prognostic factor study, Regression modelling, Vulnerability | BMC primary care |
Incidence and Determinants of Spontaneous Normalization of Subclinical Hypothyroidism in Older Adults. | van der Spoel E, van Vliet NA, Poortvliet RKE, Du Puy RS, den Elzen WPJ, Quinn TJ, Stott DJ, Sattar N, Kearney PM, Blum MR, Alwan H, Rodondi N, Collet TH, Westendorp RGJ, Ballieux BE, Jukema JW, Dekkers OM, Gussekloo J, Mooijaart SP, van Heemst D | 2024-02-20 | follow-up studies, older adults, subclinical hypothyroidism, thyrotropin | The Journal of clinical endocrinology and metabolism |
Deficits in geriatric assessment are important in relation to fatigue in older patients with Inflammatory Bowel Disease. | Fons AB, Asscher VER, Stuyt RJL, Baven-Pronk AMC, van der Marel S, Jacobs RJ, Mooijaart SP, Eikelenboom P, van der Meulen-de Jong AE, Kalisvaart KJ, Jeroen Maljaars PW | 2024-02-17 | Crohn's disease, Elderly, Ulcerative colitis | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver |
Prioritising actions to address stagnating maternal mortality rates globally. | van den Akker T, D'Souza R, Tura AK, Nair M, Engjom H, Knight M, Donati S | 2024-02-03 | Lancet (London, England) | |
Validation of biomarkers of aging. | Moqri M, Herzog C, Poganik JR, Ying K, Justice JN, Belsky DW, Higgins-Chen AT, Chen BH, Cohen AA, Fuellen G, Hägg S, Marioni RE, Widschwendter M, Fortney K, Fedichev PO, Zhavoronkov A, Barzilai N, Lasky-Su J, Kiel DP, Kennedy BK, Cummings S, Slagboom PE, Verdin E, Maier AB, Sebastiano V, Snyder MP, Gladyshev VN, Horvath S, Ferrucci L | 2024-02-01 | Nature medicine | |
Comprehensive evaluation of smoking exposures and their interactions on DNA methylation. | Hoang TT, Lee Y, McCartney DL, Kersten ETG, Page CM, Hulls PM, Lee M, Walker RM, Breeze CE, Bennett BD, Burkholder AB, Ward J, Brantsæter AL, Caspersen IH, Motsinger-Reif AA, Richards M, White JD, Zhao S, Richmond RC, Magnus MC, Koppelman GH, Evans KL, Marioni RE, Håberg SE, London SJ | 2024-02-01 | Dietary intake, Epigenomics, Illumina EPIC array, Secondhand smoke exposure, Sex difference, Smoking cessation | EBioMedicine |
Characteristics and outcomes of pregnant women hospitalized with severe maternal outcomes in eastern Ethiopia: Results from the Ethiopian Obstetric Surveillance System study. | Tura AK, Knight M, Girma S, Ahmed R, Yuya M, Bekele D, Hassen TA, Stekelenburg J, van den Akker T | 2024-02-01 | Ethiopia, audit, maternal mortality, severe maternal morbidity, surveillance | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics |
Compliance with maternal sepsis guidelines in a tertiary hospital in the Netherlands. | de Vries BS, Verschueren KJC, Jansen S, Bekker V, Veenhof MB, van den Akker T | 2024-02-01 | Maternal sepsis, early warning score, rapid response team, sepsis management, sepsis prevention, surviving sepsis campaign | Hospital practice (1995) |
Geriatric predictors of response and adverse events in older patients with cancer treated with immune checkpoint inhibitors: A systematic review. | Özkan A, van den Bos F, Mooijaart SP, Slingerland M, Kapiteijn E, de Miranda NFCC, Portielje JEA, de Glas NA | 2024-02-01 | Frailty, Geriatric oncology, Geriatric screening, Geriatric syndromes, Immune checkpoint inhibitors, Immunosenescence, Older patients, Overall survival, Systematic review, Toxicity | Critical reviews in oncology/hematology |
Apathy Symptoms, Physical and Cognitive Function, Health-Related Quality of Life, and Mortality in Older Patients With CKD: A Longitudinal Observational Study. | Voorend CGN, van Buren M, Berkhout-Byrne NC, Kerckhoffs APM, van Oevelen M, Gussekloo J, Richard E, Bos WJW, Mooijaart SP | 2024-02-01 | Apathy, cognitive dysfunction, end-stage kidney disease, frailty, geriatric assessment | American journal of kidney diseases : the official journal of the National Kidney Foundation |
The trajectory of pain and pain intensity in the upper extremity after stroke over time: a prospective study in a rehabilitation population. | van Meijeren-Pont W, Arwert H, Volker G, Fiocco M, Achterberg WP, Vliet Vlieland TPM, Oosterveer DM | 2024-02-01 | Stroke, pain, pain intensity, rehabilitation, upper extremity pain | Disability and rehabilitation |
Diagnostic accuracy of urine biomarkers for urinary tract infection in older women: a case-control study. | Bilsen MP, Treep MM, Aantjes MJ, van Andel E, Stalenhoef JE, van Nieuwkoop C, Leyten EMS, Delfos NM, van Uhm JIM, Sijbom M, Akintola AA, Numans ME, Achterberg WP, Mooijaart SP, van der Beek MT, Cobbaert CM, Conroy SP, Visser LG, Lambregts MMC | 2024-02-01 | Antimicrobial stewardship, Asymptomatic bacteriuria, Biomarkers, Diagnostic accuracy, Older patients, Urinary tract infection | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases |
Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications. | Sterenborg RBTM, Steinbrenner I, Li Y, Bujnis MN, Naito T, Marouli E, Galesloot TE, Babajide O, Andreasen L, Astrup A, Åsvold BO, Bandinelli S, Beekman M, Beilby JP, Bork-Jensen J, Boutin T, Brody JA, Brown SJ, Brumpton B, Campbell PJ, Cappola AR, Ceresini G, Chaker L, Chasman DI, Concas MP, Coutinho de Almeida R, Cross SM, Cucca F, Deary IJ, Kjaergaard AD, Echouffo Tcheugui JB, Ellervik C, Eriksson JG, Ferrucci L, Freudenberg J, Fuchsberger C, Gieger C, Giulianini F, Gögele M, Graham SE, Grarup N, Gunjača I, Hansen T, Harding BN, Harris SE, Haunsø S, Hayward C, Hui J, Ittermann T, Jukema JW, Kajantie E, Kanters JK, Kårhus LL, Kiemeney LALM, Kloppenburg M, Kühnel B, Lahti J, Langenberg C, Lapauw B, Leese G, Li S, Liewald DCM, Linneberg A, Lominchar JVT, Luan J, Martin NG, Matana A, Meima ME, Meitinger T, Meulenbelt I, Mitchell BD, Møllehave LT, Mora S, Naitza S, Nauck M, Netea-Maier RT, Noordam R, Nursyifa C, Okada Y, Onano S, Papadopoulou A, Palmer CNA, Pattaro C, Pedersen O, Peters A, Pietzner M, Polašek O, Pramstaller PP, Psaty BM, Punda A, Ray D, Redmond P, Richards JB, Ridker PM, Russ TC, Ryan KA, Olesen MS, Schultheiss UT, Selvin E, Siddiqui MK, Sidore C, Slagboom PE, Sørensen TIA, Soto-Pedre E, Spector TD, Spedicati B, Srinivasan S, Starr JM, Stott DJ, Tanaka T, Torlak V, Trompet S, Tuhkanen J, Uitterlinden AG, van den Akker EB, van den Eynde T, van der Klauw MM, van Heemst D, Verroken C, Visser WE, Vojinovic D, Völzke H, Waldenberger M, Walsh JP, Wareham NJ, Weiss S, Willer CJ, Wilson SG, Wolffenbuttel BHR, Wouters HJCM, Wright MJ, Yang Q, Zemunik T, Zhou W, Zhu G, Zöllner S, Smit JWA, Peeters RP, Köttgen A, Teumer A, Medici M | 2024-01-30 | Nature communications | |
Differences in rates of severe perineal trauma between midwife-led and obstetrician-led care in the Netherlands: A nationwide cohort study. | Seijmonsbergen-Schermers AE, Peerdeman KM, van den Akker T, Titulaer LM, Roovers JP, Peters LL, Verhoeven CJ, de Jonge A | 2024-01-30 | Care providers, Interventions, Maternity care setting, OASI, Obstetric anal sphincter injury, Place of birth, Risk factors, SPT, Severe perineal trauma | Heliyon |
Inequalities in use of hospitals for childbirth among rural women in sub-Saharan Africa: a comparative analysis of 18 countries using Demographic and Health Survey data. | Straneo M, Hanson C, van den Akker T, Afolabi BB, Asefa A, Delamou A, Dennis M, Gadama L, Mahachi N, Mlilo W, Pembe AB, Tsuala Fouogue J, Beňová L | 2024-01-22 | Epidemiology, Health systems, Maternal health, Obstetrics | BMJ global health |
Incidence and determinants of perinatal mortality in five urban hospitals in Dar es Salaam, Tanzania: a cohort study with an embedded case-control analysis. | Sequeira Dmello B, John TW, Housseine N, Meyrowitsch DW, van Roosmalen J, van den Akker T, Kujabi ML, Festo C, Nkungu D, Muniro Z, Kabanda I, Msumi R, Maembe L, Sangalala M, Hyera E, Lema J, Bayongo S, Mshiu J, Kidanto HL, Maaløe N | 2024-01-13 | CCBRT, Dar es Salaam, Hypertensive disorders in pregnancy, Neonatal deaths, PartoMa, Perinatal deaths, Quality of care, Stillbirths, Tanzania, Urban health | BMC pregnancy and childbirth |
An exploration of relocation initiatives deployed within and between nursing homes: a qualitative study. | Broekharst DSE, Stoop A, Achterberg WP, Caljouw MAA | 2024-01-04 | Bridging initiatives, Nursing homes, Older adults, Post-relocation initiatives, Pre-relocation initiatives, Relocation initiatives | BMC health services research |
Distinct functional subnetworks of cognitive domains in older adults with minor cognitive deficits. | Drenth N, van Dijk SE, Foster-Dingley JC, Bertens AS, Rius Ottenheim N, van der Mast RC, Rombouts SARB, van Rooden S, van der Grond J | 2024-01-01 | cognitive domains, functional MRI, functional connectivity, older adults, resting-state networks | Brain communications |
Modifying a multidisciplinary method to address challenging behavior in nursing home residents with dementia to involve family caregivers. | Tasseron-Dries PEM, Smaling HJA, van der Steen JT, Achterberg WP | 2024-01-01 | challenging behavior, dementia, family involvement, intervention, nursing home, pain | Frontiers in dementia |
Length-of-stay and factors associated with early discharge after birth in health facilities in Guinea by mode of birth: Secondary analysis of Demographic and Health Survey 2018. | Semaan A, Grovogui FM, Delvaux T, Housseine N, van den Akker T, Delamou A, Beňová L | 2024-01-01 | PLOS global public health | |
The ageing thyroid: implications for longevity and patient care. | van Heemst D | 2024-01-01 | Nature reviews. Endocrinology | |
Association of Biological Age with Tumor Microenvironment in Patients with Esophageal Adenocarcinoma. | Ravensbergen C, van Holstein Y, Hagenaars S, Crobach S, Trompet S, Portielje J, de Glas N, van Heemst D, van den Bos F, Tollenaar R, Mesker W, Mooijaart S, Slingerland M | 2024-01-01 | Biological age, Esophageal cancer, Frailty, Geriatric assessment, Tumor microenvironment | Gerontology |
Experiences of community health workers on adopting mHealth in rural Malawi: A qualitative study. | Kachimanga C, Mulwafu M, Ndambo MK, Harare J, Murkherjee J, Kulinkina AV, Mbae S, Ndarama E, van den Akker T, Abejirinde IO | 2024-01-01 | Malawi, community health workers, mHealth, maternal health | Digital health |
HIV seroconversion among female sex workers: retrospective cohort study from a large-scale HIV prevention and sexual and reproductive health program in Tanzania. | Mbita G, Mwanamsangu A, Komba AN, Casalini C, Luponya M, Curran K, Christensen A, Kim YM, Reed J, Makyao N, Kategile U, Conserve DF, van Roosmalen J, van den Akker T | 2024-01-01 | HIV seroconversion, HIV/AIDS (acquired immunodeficiency syndrome), Tanzania, female sex workers (FSWs), key populations | Frontiers in reproductive health |
What are best practices for involving family caregivers in interventions aimed at responsive behaviour stemming from unmet needs of people with dementia in nursing homes: a scoping review. | Tasseron-Dries PEM, Smaling HJA, Nakanishi M, Achterberg WP, van der Steen JT | 2023-12-07 | Dementia, PALLIATIVE CARE, QUALITATIVE RESEARCH, Quality of Life | BMJ open |
Inconsistent definitions of labour progress and over-medicalisation cause unnecessary harm during birth. | Maaløe N, Kujabi ML, Nathan NO, Skovdal M, Dmello BS, Wray S, van den Akker T, Housseine N | 2023-12-06 | BMJ (Clinical research ed.) | |
Postpartum haemorrhage in high-resource settings: Variations in clinical management and future research directions based on a comparative study of national guidelines. | de Vries PLM, Deneux-Tharaux C, Baud D, Chen KK, Donati S, Goffinet F, Knight M, D'Souzah R, Sueters M, van den Akker T | 2023-12-01 | clinical guidelines, obstetric haemorrhage, postpartum haemorrhage | BJOG : an international journal of obstetrics and gynaecology |
Spontaneous haemoperitoneum in pregnancy: Nationwide surveillance and Delphi audit system. | Schreurs AMF, Overtoom EM, de Boer MA, van der Houwen LEE, Lier MCI, van den Akker T, Cornette J, Vogelvang TE, Beenakkers ICM, Rosman AN, Maas JWM, Heineman DJ, Finken MJJ, de Vries JJJ, Burger NB, Schaap TP, Bloemenkamp KWM, Mijatovic V | 2023-12-01 | ART, NethOSS, SHiP, endometriosis, fetal morbidity, maternal morbidity, obstetric surveillance system | BJOG : an international journal of obstetrics and gynaecology |
Prophylactic radiologic interventions to reduce postpartum hemorrhage in women with risk factors for placenta accreta spectrum disorder: a nationwide cohort study. | Bonsen LR, Harskamp V, Feddouli S, Bloemenkamp KWM, Duvekot JJ, Pors A, van Roosmalen J, Zwart JJ, van Lith JMM, Hendriks J, Urlings TAJ, van den Akker T, van der Bom JG, Henriquez DDCA | 2023-12-01 | Placenta accreta spectrum, maternal morbidity, postpartum hemorrhage, radiologic interventions | The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians |
Confidential Enquiry into Maternal Deaths in Namibia, 2018-2019: A Local Approach to Strengthen the Review Process and a Description of Review Findings and Recommendations. | Heemelaar S, Callard B, Shikwambi H, Ellmies J, Kafitha W, Stekelenburg J, van den Akker T, Mackenzie S | 2023-12-01 | HIV, Maternal mortality, Namibia | Maternal and child health journal |
White matter hyperintensity shape is associated with long-term dementia risk. | Keller JA, Sigurdsson S, Klaassen K, Hirschler L, van Buchem MA, Launer LJ, van Osch MJP, Gudnason V, de Bresser J | 2023-12-01 | cerebral small vessel disease, cognitive decline, dementia, magnetic resonance imaging, white matter hyperintensities | Alzheimer's & dementia : the journal of the Alzheimer's Association |
Functioning and recovery during stroke rehabilitation: a comparison between pre-stroke frail and non-frail patients. | Mennema Å, Vliet Vlieland TPM, Achterberg WP, Oosterveer DM | 2023-12-01 | Frailty, Outcomes, Rehabilitation, Stroke | European geriatric medicine |
Priority measures to prevent infections and maintain residents’ well-being during COVID-19 outbreaks in nursing homes: Consensus among staff and resident representatives determined in an online nominal group technique study. | van Tol LS, Smaling HJA, Janus SIM, Caljouw MAA, Achterberg WP | 2023-12-01 | COVID-19, Decision making, Infection prevention, Measures, Nursing homes, Policy making, Well-being | International journal of nursing studies advances |
Technical Report: A Comprehensive Comparison between Different Quantification Versions of Nightingale Health’s 1H-NMR Metabolomics Platform. | Bizzarri D, Reinders MJT, Beekman M, Slagboom PE, van den Akker EB, On Behalf Of The BbmriNl | 2023-11-30 | NMR metabolomics, epidemiology, multivariate risk models, nightingale health, re-quantification | Metabolites |
Facilitators and barriers of implementation of routine postnatal care guidelines for women: A systematic scoping review using critical interpretive synthesis. | Beňová L, Semaan A, Portela A, Bonet M, van den Akker T, Pembe AB, Moran A, Duclos D | 2023-11-24 | Journal of global health | |
Consensus definition of advance care planning in dementia: A 33‐country Delphi study | van der Steen JT, Nakanishi M, Van den Block L, Di Giulio P, Gonella S, in der Schmitten J, Sudore RL, Harrison Dening K, Parker D, Mimica N, Holmerova I, Larkin P, Martins Pereira S, Rietjens JAC, Korfage IJ | 2023-11-20 | Alzheimer's & Dementia | |
Identified senescence endotypes in aged cartilage are reflected in the blood metabolome | Boone I, Tuerlings M, Coutinho de Almeida R, Lehmann J, Ramos Y, Nelissen R, Slagboom E, de Keizer P, Meulenbelt I | 2023-11-14 | GeroScience | |
Becoming a physician for older patients: exploring the professional identity formation of medical students during a nursing home clerkship. A qualitative study. | Moll-Jongerius A, Langeveld K, Helmich E, Masud T, Kramer AWM, Achterberg WP | 2023-11-07 | Clerkship, Community of practice, Medical students, Nursing home, Older persons, Professional identity formation | BMC medical education |
Delirium in older patients with COVID-19: Prevalence, risk factors and clinical outcomes across the first three waves of the pandemic. | Minnema J, Tap L, van der Bol JM, van Deudekom FJA, Faes MC, Jansen SWM, van der Linden CMJ, Lucke JA, Mooijaart SP, van Munster B, Noordam R, van Raaij BFM, Ruiter R, Smits RAL, Willems HC, Mattace-Raso FUS, Polinder-Bos HA | 2023-11-01 | COVID-19, SARS-CoV-2, delirium, frailty, metabolic encephalopathy, older adults | International journal of geriatric psychiatry |
Prevalence, Severity and Impact of Visuospatial Neglect in Geriatric Stroke Rehabilitation, a Cross-Sectional Study. | Bosma MS, Caljouw MAA, Achterberg WP, Nijboer TCW | 2023-11-01 | Geriatric rehabilitation, assessment, functional outcome, measurement, neglect, prevalence, severity, stroke | Journal of the American Medical Directors Association |
Metabolomic biomarkers of habitual B vitamin intakes unveil novel differentially methylated positions in the human epigenome. | Costeira R, Evangelista L, Wilson R, Yan X, Hellbach F, Sinke L, Christiansen C, Villicaña S, Masachs OM, Tsai PC, Mangino M, Menni C, Berry SE, Beekman M, van Heemst D, Slagboom PE, Heijmans BT, Suhre K, Kastenmüller G, Gieger C, Peters A, Small KS, Linseisen J, Waldenberger M, Bell JT | 2023-10-19 | B vitamins, Biomarkers, DNA methylation, Diet, Folate, Metabolomics | Clinical epigenetics |
Consequences of contact restrictions for long-term care residents during the first months of COVID-19 pandemic: a scoping review. | Benzinger P, Wahl HW, Bauer JM, Keilhauer A, Dutzi I, Maier S, Hölzer N, Achterberg WP, Denninger NE | 2023-10-17 | Care facility, Coronavirus, Health consequences, Loneliness, Nursing home, Quality of life | European journal of ageing |
Epigenetic and Metabolomic Biomarkers for Biological Age: A Comparative Analysis of Mortality and Frailty Risk. | Kuiper LM, Polinder-Bos HA, Bizzarri D, Vojinovic D, Vallerga CL, Beekman M, Dollé ET, Ghanbari M, Voortman T, Reinders MJT, Verschuren WMM, Slagboom PE, van den Akker EB, van Meurs JBJ | 2023-10-09 | DNA methylation, Frailty, Mortality | The journals of gerontology. Series A, Biological sciences and medical sciences |
[Ethnicity as a prognostic factor in extreme preterm birth]. | De Proost L, Van den Akker T, Haalboom F, Verweij EJ | 2023-10-04 | Nederlands tijdschrift voor geneeskunde | |
Chemotherapy-Related Toxic Effects and Quality of Life and Physical Functioning in Older Patients. | Baltussen JC, de Glas NA, van Holstein Y, van der Elst M, Trompet S, Uit den Boogaard A, van der Plas-Krijgsman W, Labots G, Holterhues C, van der Bol JM, Mammatas LH, Liefers GJ, Slingerland M, van den Bos F, Mooijaart SP, Portielje JEA | 2023-10-02 | JAMA network open | |
Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification. | Kavousi M, Bos MM, Barnes HJ, Lino Cardenas CL, Wong D, Lu H, Hodonsky CJ, Landsmeer LPL, Turner AW, Kho M, Hasbani NR, de Vries PS, Bowden DW, Chopade S, Deelen J, Benavente ED, Guo X, Hofer E, Hwang SJ, Lutz SM, Lyytikäinen LP, Slenders L, Smith AV, Stanislawski MA, van Setten J, Wong Q, Yanek LR, Becker DM, Beekman M, Budoff MJ, Feitosa MF, Finan C, Hilliard AT, Kardia SLR, Kovacic JC, Kral BG, Langefeld CD, Launer LJ, Malik S, Hoesein FAAM, Mokry M, Schmidt R, Smith JA, Taylor KD, Terry JG, van der Grond J, van Meurs J, Vliegenthart R, Xu J, Young KA, Zilhão NR, Zweiker R, Assimes TL, Becker LC, Bos D, Carr JJ, Cupples LA, de Kleijn DPV, de Winther M, den Ruijter HM, Fornage M, Freedman BI, Gudnason V, Hingorani AD, Hokanson JE, Ikram MA, Išgum I, Jacobs DR, Kähönen M, Lange LA, Lehtimäki T, Pasterkamp G, Raitakari OT, Schmidt H, Slagboom PE, Uitterlinden AG, Vernooij MW, Bis JC, Franceschini N, Psaty BM, Post WS, Rotter JI, Björkegren JLM, O'Donnell CJ, Bielak LF, Peyser PA, Malhotra R, van der Laan SW, Miller CL | 2023-10-01 | Nature genetics | |
The impact of sociodemographic status on the association of classical cardiovascular risk factors with coronary artery disease: a stratified Mendelian randomization study. | Martens LG, van Hamersveld D, le Cessie S, Willems van Dijk K, van Heemst D, Noordam R | 2023-10-01 | Body mass index, Cardiovascular diseases, Coronary artery disease, Effect modification, Mendelian randomization, Socioeconomic status | Journal of clinical epidemiology |
Habitual sleep quantity and quality and the risk of obesity: What’s the chicken, and what’s the egg? | Noordam R, van Heemst D | 2023-10-01 | Sleep medicine | |
The optimal healthy ranges of thyroid function defined by the risk of cardiovascular disease and mortality: systematic review and individual participant data meta-analysis. | Xu Y, Derakhshan A, Hysaj O, Wildisen L, Ittermann T, Pingitore A, Abolhassani N, Medici M, Kiemeney LALM, Riksen NP, Dullaart RPF, Trompet S, Dörr M, Brown SJ, Schmidt B, Führer-Sakel D, Vanderpump MPJ, Muendlein A, Drexel H, Fink HA, Ikram MK, Kavousi M, Rhee CM, Bensenor IM, Azizi F, Hankey GJ, Iacoviello M, Imaizumi M, Ceresini G, Ferrucci L, Sgarbi JA, Bauer DC, Wareham N, Boelaert K, Bakker SJL, Jukema JW, Vaes B, Iervasi G, Yeap BB, Westendorp RGJ, Korevaar TIM, Völzke H, Razvi S, Gussekloo J, Walsh JP, Cappola AR, Rodondi N, Peeters RP, Chaker L | 2023-10-01 | The lancet. Diabetes & endocrinology | |
Interventions that may increase control at the end of life in persons with dementia: the cross-cultural CONT-END acceptability study protocol and pilot-testing. | Smaling HJA, Jingyuan X, Nakanishi M, Shinan-Altman S, Mehr DR, Radbruch L, Gaertner J, Werner P, Achterberg WP, van der Steen JT | 2023-09-27 | Advance care planning, Assisted death, Dementia, End of life, Euthanasia, Palliative care, Technology | BMC palliative care |
Maternal mortality is preventable in Lebanon: A case series of maternal deaths to identify lessons learned using the “Three Delays” model. | Rebeiz MC, El-Kak F, van den Akker T, Hamadeh R, McCall SJ | 2023-09-01 | COVID-19, amniotic fluid embolism, avoidable, hypertensive disorders, maternal mortality, postpartum hemorrhage, preventable, sepsis | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics |
Binational confidential enquiry of maternal deaths due to postpartum hemorrhage in France and the Netherlands: Lessons learned through the perspective of a different context of care. | de Vries PLM, van den Akker T, Bloemenkamp KWM, Grossetti E, Rigouzzo A, Saucedo M, Verspyck E, Zwart J, Deneux-Tharaux C | 2023-09-01 | France, confidential enquiry into maternal deaths, maternal mortality, maternity care, obstetrics, postpartum hemorrhage, the Netherlands | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics |
The association of blood biomarkers with treatment response and adverse health outcomes in older patients with solid tumors: A systematic review. | van Holstein Y, van den Berkmortel PJE, Trompet S, van Heemst D, van den Bos F, Roemeling-van Rhijn M, de Glas NA, Beekman M, Slagboom PE, Portielje JEA, Mooijaart SP, van Munster BC | 2023-09-01 | Blood biomarker, Geriatric oncology, Outcome, cancer | Journal of geriatric oncology |
The Role of a Composite Fitness Score in the Association Between Low-Density Cholesterol and All-Cause Mortality in Older Adults: An Individual Patient Data Meta-Analysis. | van der Ploeg MA, Poortvliet RKE, Bogaerts JMK, van der Klei VMGTH, Kerse N, Rolleston A, Teh R, Robinson L, Jagger C, Arai Y, Shikimoto R, Abe Y, Blom JW, Drewes YM, Gussekloo J | 2023-08-27 | Activities of daily living, Cognition, Frailty, Grip strength, Oldest old | The journals of gerontology. Series A, Biological sciences and medical sciences |
Effects of smoking on genome-wide DNA methylation profiles: A study of discordant and concordant monozygotic twin pairs. | van Dongen J, Willemsen G, de Geus EJC, Boomsma DI, Neale MC | 2023-08-10 | DNA methylation, discordant twins, epidemiology, epigenetics, genetics, genomics, global health, human, identical twins, twin study | eLife |
Pulmonary oedema in the course of severe maternal outcome in South Africa: A cohort study combined with clinical audit. | Heitkamp A, Sandberg E, Moodley A, Burke J, van Roosmalen J, Gebhardt S, Vollmer L, de Vries JI, van den Akker T, Theron G | 2023-08-01 | South Africa, audit, high-risk pregnancy, obstetrics, pulmonary oedema, severe maternal outcome | Tropical medicine & international health : TM & IH |
Sex differences in dementia risk and risk factors: Individual-participant data analysis using 21 cohorts across six continents from the COSMIC consortium. | Gong J, Harris K, Lipnicki DM, Castro-Costa E, Lima-Costa MF, Diniz BS, Xiao S, Lipton RB, Katz MJ, Wang C, Preux PM, Guerchet M, Gbessemehlan A, Ritchie K, Ancelin ML, Skoog I, Najar J, Sterner TR, Scarmeas N, Yannakoulia M, Kosmidis MH, Guaita A, Rolandi E, Davin A, Gureje O, Trompet S, Gussekloo J, Riedel-Heller S, Pabst A, Röhr S, Shahar S, Singh DKA, Rivan NFM, Boxtel MV, Köhler S, Ganguli M, Chang CC, Jacobsen E, Haan M, Ding D, Zhao Q, Xiao Z, Narazaki K, Chen T, Chen S, Ng TP, Gwee X, Numbers K, Mather KA, Scazufca M, Lobo A, De-la-Cámara C, Lobo E, Sachdev PS, Brodaty H, Hackett ML, Peters SAE, Woodward M | 2023-08-01 | data harmonization, dementia, diversity, risk factor, sex difference | Alzheimer's & dementia : the journal of the Alzheimer's Association |
Measuring Pain in Aphasia: Validity and Reliability of the PACSLAC-D. | de Vries NJ, van der Steen JT, Achterberg WP, Smaling HJA | 2023-08-01 | Pain management nursing : official journal of the American Society of Pain Management Nurses | |
Towards optimal use of antithrombotic therapy of people with cancer at the end of life: A research protocol for the development and implementation of the SERENITY shared decision support tool. | Goedegebuur J, Abbel D, Accassat S, Achterberg WP, Akbari A, Arfuch VM, Baddeley E, Bax JJ, Becker D, Bergmeijer B, Bertoletti L, Blom JW, Calvetti A, Cannegieter SC, Castro L, Chavannes NH, Coma-Auli N, Couffignal C, Edwards A, Edwards M, Enggaard H, Font C, Gava A, Geersing GJ, Geijteman ECT, Greenley S, Gregory C, Gussekloo J, Hoffmann I, Højen AA, van den Hout WB, Huisman MV, Jacobsen S, Jagosh J, Johnson MJ, Jørgensen L, Juffermans CCM, Kempers EK, Konstantinides S, Kroder AF, Kruip MJHA, Lafaie L, Langendoen JW, Larsen TB, Lifford K, van der Linden YM, Mahé I, Maiorana L, Maraveyas A, Martens ESL, Mayeur D, van Mens TE, Mohr K, Mooijaart SP, Murtagh FEM, Nelson A, Nielsen PB, Ording AG, Ørskov M, Pearson M, Poenou G, Portielje JEA, Raczkiewicz D, Rasmussen K, Trinks-Roerdink E, Schippers I, Seddon K, Sexton K, Sivell S, Skjøth F, Søgaard M, Szmit S, Trompet S, Vassal P, Visser C, van Vliet LM, Wilson E, Klok FA, Noble SIR | 2023-08-01 | Anticoagulants, Deprescriptions, Hemorrhage, Neoplasms, Palliative care, Thrombosis | Thrombosis research |
Increasing number of long-lived ancestors marks a decade of healthspan extension and healthier metabolomics profiles. | van den Berg N, Rodríguez-Girondo M, van Dijk IK, Slagboom PE, Beekman M | 2023-07-27 | Nature communications | |
Preoperative thalamus volume is not associated with preoperative cognitive impairment (preCI) or postoperative cognitive dysfunction (POCD). | Fislage M, Feinkohl I, Borchers F, Pischon T, Spies CD, Winterer G, Zacharias N | 2023-07-20 | Scientific reports | |
eHealth in Geriatric Rehabilitation: An International Survey of the Experiences and Needs of Healthcare Professionals. | Kraaijkamp JJM, Persoon A, Aurelian S, Bachmann S, Cameron ID, Choukou MA, Dockery F, Eruslanova K, Gordon AL, Grund S, Kim H, Maier AB, Pérez Bazan LM, Pompeu JE, Topinkova E, Vassallo MA, Chavannes NH, Achterberg WP, Van Dam van Isselt EF | 2023-07-05 | barriers and facilitators, eHealth, geriatric rehabilitation, implementation, information needs | Journal of clinical medicine |
Hepatic triglyceride content is intricately associated with numerous metabolites and biochemical pathways. | Faquih TO, van Klinken JB, Li-Gao R, Noordam R, van Heemst D, Boone S, Sheridan PA, Michelotti G, Lamb H, de Mutsert R, Rosendaal FR, van Hylckama Vlieg A, van Dijk KW, Mook-Kanamori DO | 2023-07-01 | dysregulation, genetic targets, liver triglyceride content, metabolomics, pathway analysis | Liver international : official journal of the International Association for the Study of the Liver |
Differential and sex- and age-specific risks of cardiometabolic diseases with unrelated metabolic syndrome dimensions. | Ao L, Willems van Dijk K, van Heemst D, Noordam R | 2023-07-01 | Obesity (Silver Spring, Md.) | |
A novel approach for pharmacological substantiation of safety signals using plasma concentrations of medication and administrative/healthcare databases: A case study using Danish registries for an FDA warning on lamotrigine. | Wang W, Battini V, Carnovale C, Noordam R, van Dijk KW, Kragholm KH, van Heemst D, Soeorg H, Sessa M | 2023-07-01 | Lamotrigine, Mortality, Pharmacoepidemiology, Pharmacometrics | Pharmacological research |
Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH. | Li JH, Brenner LN, Kaur V, Figueroa K, Schroeder P, Huerta-Chagoya A, Udler MS, Leong A, Mercader JM, Florez JC | 2023-07-01 | Genetics, Genome-wide association study, Glipizide, Incretin, Metformin, Multi-ancestry, Pathophysiology, Pharmacogenetics, Sulfonylurea, Type 2 diabetes | Diabetologia |
Cardiovascular risk factors and major recurrent coronary events: A genetic liability study in patients with coronary artery disease in the UK Biobank. | Noordam R, Brochard TA, Drewes YM, Gussekloo J, Mooijaart SP, Willems van Dijk K, Trompet S, Jukema JW, van Heemst D | 2023-07-01 | LDL cholesterol, Mendelian randomization, coronary artery disease, recurrent disease | Atherosclerosis |
“So let me give you money, you give me what I want”: decision-making priorities around contraceptive method and source choice among young women in Kenya. | Calhoun LM, Mandal M, Onyango B, Waga E, McGuire C, van den Akker T, Beňová L, Delvaux T, Zulu EM, Speizer IS | 2023-06-26 | Family planning, Method choice, Method source, Service delivery point, Youth | Reproductive health |
Impact of anesthetist licensing examination on quality of education in Ethiopia: a qualitative study of faculty and student perceptions. | Asemu YM, Yigzaw T, Desta FA, Melese TA, Gemeda LA, Scheele F, van den Akker T | 2023-06-22 | Anesthesia, Assessment, Associate clinician anesthetists, Education Quality, National Licensing Examination, Non-physician anesthetists | BMC medical education |
Current Pyuria Cutoffs Promote Inappropriate Urinary Tract Infection Diagnosis in Older Women. | Bilsen MP, Aantjes MJ, van Andel E, Stalenhoef JE, van Nieuwkoop C, Leyten EMS, Delfos NM, Sijbom M, Numans ME, Achterberg WP, Mooijaart SP, van der Beek MT, Cobbaert CM, Conroy SP, Visser LG, Lambregts MMC | 2023-06-16 | asymptomatic bacteriuria, microscopy, pyuria, urinary tract infection, urine flowcytometry | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America |
Out of sight, out of mind? Evidence from cross-sectional surveys on hidden caesarean sections among women with stillbirths in Ghana, 2007 and 2017. | Zethof S, Christou A, Benova L, Beyuo TK, van Roosmalen J, van den Akker T | 2023-06-01 | cross-sectional survey, indices of health and disease and standardisation of rates, maternal health, obstetrics, surgery | BMJ global health |
Biomarkers of the ageing immune system and their association with frailty – A systematic review. | Tran Van Hoi E, De Glas NA, Portielje JEA, Van Heemst D, Van Den Bos F, Jochems SP, Mooijaart SP | 2023-06-01 | Ageing, Biomarkers, Elderly, Frailty, Immunosenescence, Inflammaging | Experimental gerontology |
Correction to: palliative care in advanced Huntington’s disease: a scoping review. | Boersema-Wijma DJ, van Duijn E, Heemskerk AW, van der Steen JT, Achterberg WP | 2023-05-31 | BMC palliative care | |
Temporal changes in characteristics and external validity of randomized controlled trials in older people from 2012 to 2019. | van Eijk E, van der Spek YM, van Deudekom FJA, van den Bos F, Mooijaart SP, Trompet S | 2023-05-24 | Geriatric assessments, Older individuals, Randomized controlled trials, Systematic review, Temporal changes | BMC geriatrics |
Frequencies and reasons for unplanned emergency department return visits by older adults: a cohort study. | van Loon-van Gaalen M, Voshol IE, van der Linden MC, Gussekloo J, van der Mast RC | 2023-05-18 | Emergency department, Geriatric, Older patients, Return presentations, Unplanned return | BMC geriatrics |
Time trends in treatment patterns and survival of older patients with synchronous metastatic colorectal cancer in the Netherlands: A population-based study. | Baltussen JC, de Glas NA, Liefers GJ, Slingerland M, Speetjens FM, van den Bos F, Cloos-van Balen M, Verschoor AJ, Jochems A, Spierings LEAMM, Holterhues C, van Gerven LA, Mooijaart SP, Portielje JEA, Derks MGM | 2023-05-15 | metastatic colorectal cancer, older adults, population-based study, survival, treatment patterns | International journal of cancer |
Uncovering the Relationship between Selenium Status, Age, Health, and Dietary Habits: Insights from a Large Population Study including Nonagenarian Offspring from the MARK-AGE Project. | Giacconi R, Piacenza F, Aversano V, Zampieri M, Bürkle A, Villanueva MM, Dollé MET, Jansen E, Grune T, Gonos ES, Franceschi C, Capri M, Weinberger B, Sikora E, Toussaint O, Debacq-Chainiaux F, Stuetz W, Slagboom PE, Bernhardt J, Fernández-Sánchez ML, Provinciali M, Malavolta M | 2023-05-04 | aging, inflammation, longevity, plasma selenium, selenium fractionation | Nutrients |
Prevalence and risk factors of burden among caregivers of older emergency department patients. | Zaalberg T, Barten DG, van Heugten CM, Klijnsma P, Knarren L, Hiemstra Y, Kurvers RAJ, Lekx AW, Mooijaart SP, Janssen-Heijnen M | 2023-05-04 | Scientific reports | |
Palliative care in advanced Huntington’s disease: a scoping review. | Boersema-Wijma DJ, van Duijn E, Heemskerk AW, van der Steen JT, Achterberg WP | 2023-05-03 | Advance Care Planning, Hospice Care, Huntington’s Disease, Neurodegenerative diseases, Palliative Care, Terminal Care | BMC palliative care |
Low leukocyte mitochondrial DNA abundance drives atherosclerotic cardiovascular diseases: a cohort and Mendelian randomization study. | Luo J, Noordam R, Jukema JW, van Dijk KW, Hägg S, Grassmann F, le Cessie S, van Heemst D | 2023-05-02 | Coronary artery disease, Heart failure, Mendelian randomization, Mitochondrial DNA | Cardiovascular research |
Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus. | Mathieson I, Day FR, Barban N, Tropf FC, Brazel DM, Vaez A, van Zuydam N, Bitarello BD, Gardner EJ, Akimova ET, Azad A, Bergmann S, Bielak LF, Boomsma DI, Bosak K, Brumat M, Buring JE, Cesarini D, Chasman DI, Chavarro JE, Cocca M, Concas MP, Davey Smith G, Davies G, Deary IJ, Esko T, Faul JD, Franco O, Ganna A, Gaskins AJ, Gelemanovic A, de Geus EJC, Gieger C, Girotto G, Gopinath B, Grabe HJ, Gunderson EP, Hayward C, He C, van Heemst D, Hill WD, Hoffmann ER, Homuth G, Hottenga JJ, Huang H, Hyppӧnen E, Ikram MA, Jansen R, Johannesson M, Kamali Z, Kardia SLR, Kavousi M, Kifley A, Kiiskinen T, Kraft P, Kühnel B, Langenberg C, Liew G, Lind PA, Luan J, Mägi R, Magnusson PKE, Mahajan A, Martin NG, Mbarek H, McCarthy MI, McMahon G, Medland SE, Meitinger T, Metspalu A, Mihailov E, Milani L, Missmer SA, Mitchell P, Møllegaard S, Mook-Kanamori DO, Morgan A, van der Most PJ, de Mutsert R, Nauck M, Nolte IM, Noordam R, Penninx BWJH, Peters A, Peyser PA, Polašek O, Power C, Pribisalic A, Redmond P, Rich-Edwards JW, Ridker PM, Rietveld CA, Ring SM, Rose LM, Rueedi R, Shukla V, Smith JA, Stankovic S, Stefánsson K, Stöckl D, Strauch K, Swertz MA, Teumer A, Thorleifsson G, Thorsteinsdottir U, Thurik AR, Timpson NJ, Turman C, Uitterlinden AG, Waldenberger M, Wareham NJ, Weir DR, Willemsen G, Zhao JH, Zhao W, Zhao Y, Snieder H, den Hoed M, Ong KK, Mills MC, Perry JRB | 2023-05-01 | Nature human behaviour | |
Effect of clinical chorioamnionitis on breathing effort in premature infants at birth: a retrospective case-control study. | Panneflek TJR, Kuypers KLAM, Polglase GR, Hooper SB, van den Akker T, Te Pas AB | 2023-05-01 | Allergy and Immunology, intensive care units, neonatal, neonatology, resuscitation | Archives of disease in childhood. Fetal and neonatal edition |
Vacuum extraction or caesarean section in the second stage of labour: A systematic review. | Thierens S, van Binsbergen A, Nolens B, van den Akker T, Bloemenkamp K, Rijken MJ | 2023-05-01 | caesarean section, maternal, morbidity, mortality, neonatal, operative vaginal delivery, perinatal, vacuum extraction | BJOG : an international journal of obstetrics and gynaecology |
Association between endocrine therapy and cognitive decline in older women with early breast cancer: Findings from the prospective CLIMB study. | Baltussen JC, Derks MGM, Lemij AA, de Glas NA, Fiocco M, Linthorst-Niers EMH, Vulink AJE, van Gerven L, Guicherit OR, van Dalen T, Merkus JWS, Lans TE, van der Pol CC, Mooijaart SP, Portielje JEA, Liefers GJ | 2023-05-01 | Breast cancer, Cognition, Endocrine therapy, Longitudinal, MMSE, Older women | European journal of cancer (Oxford, England : 1990) |
Establishing the Ethiopian Obstetric Surveillance System for Monitoring Maternal Outcomes in Eastern Ethiopia: A Pilot Study. | Tura AK, Girma S, Dessie Y, Bekele D, Stekelenburg J, van den Akker T, Knight M | 2023-04-28 | Global health, science and practice | |
Effects of discontinuation of levothyroxine treatment in older adults: protocol for a self-controlled trial. | Ravensberg AJ, Poortvliet RKE, Du Puy RS, Dekkers OM, Mooijaart SP, Gussekloo J | 2023-04-25 | Aged, GENERAL MEDICINE (see Internal Medicine), GERIATRIC MEDICINE, PRIMARY CARE, Quality of Life, Thyroid disease | BMJ open |
Informal Caregiver Stroke Program in Geriatric Rehabilitation of Stroke Patients: A Qualitative Study. | Vielvoye M, Nanninga CS, Achterberg WP, Caljouw MAA | 2023-04-24 | caregiver burden, geriatric rehabilitation, informal caregiver, qualitative, stroke | Journal of clinical medicine |
A study protocol of external validation of eight COVID-19 prognostic models for predicting mortality risk in older populations in a hospital, primary care, and nursing home setting. | Zahra A, Luijken K, Abbink EJ, van den Berg JM, Blom MT, Elders P, Festen J, Gussekloo J, Joling KJ, Melis R, Mooijaart S, Peters JB, Polinder-Bos HA, van Raaij BFM, Smorenberg A, la Roi-Teeuw HM, Moons KGM, van Smeden M | 2023-04-04 | COVID-19, COVID-19-related mortality, External validation, Older, Prognostic models | Diagnostic and prognostic research |
Pooled analysis of epigenome-wide association studies of food consumption in KORA, TwinsUK and LLS. | Hellbach F, Sinke L, Costeira R, Baumeister SE, Beekman M, Louca P, Leeming ER, Mompeo O, Berry S, Wilson R, Wawro N, Freuer D, Hauner H, Peters A, Winkelmann J, Koenig W, Meisinger C, Waldenberger M, Heijmans BT, Slagboom PE, Bell JT, Linseisen J | 2023-04-01 | Diet, EWAS, Food group, High-fat foods, Humans | European journal of nutrition |
Atypical presentation of COVID-19 in older patients is associated with frailty but not with adverse outcomes. | van Son JE, Kahn ECP, van der Bol JM, Barten DG, Blomaard LC, van Dam C, Ellerbroek J, Jansen SWM, Lekx A, van der Linden CMJ, Looman R, Maas HAAM, Mattace-Raso FUS, Mooijaart SP, van Munster BC, Peters A, Polinder-Bos HA, Smits RAL, Spies PE, Wassenburg A, Wassenburg N, Willems HC, Schouten HJ, Robben SHM | 2023-04-01 | Atypical presentation, COVID-19, Frailty, Older adults, SARS-CoV-2 | European geriatric medicine |
The Perceived Impact of the Namaste Care Family Program on Nursing Home Residents with Dementia, Staff, and Family Caregivers: A Qualitative Study. | Smaling HJA, Francke AL, Achterberg WP, Joling KJ, van der Steen JT | 2023-04-01 | Namaste Care, challenging behavior, dementia, nursing home, person-centered care | Journal of palliative care |
Geriatric rehabilitation care after hip fracture. | Mattiazzo GF, Drewes YM, van Eijk M, Achterberg WP | 2023-04-01 | Care pathways, Geriatric rehabilitation, Hip fractures, Standard care | European geriatric medicine |
Proxy Decision-Making for Clinical Research in Nursing Home Residents with Dementia: A Qualitative Analysis. | Bogaerts JMK, Warmerdam LA, Achterberg WP, Gussekloo J, Poortvliet RKE | 2023-04-01 | Dementia, nursing home, proxy decision-making, qualitative study, randomized controlled trial, research | Journal of the American Medical Directors Association |
Cortical iron accumulation in MAPT‐ and C9orf 72‐associated frontotemporal lobar degeneration | Giannini LAA, Bulk M, Kenkhuis B, Rajicic A, Melhem S, Hegeman‐Kleinn I, Bossoni L, Suidgeest E, Dopper EGP, van Swieten JC, van der Weerd L, Seelaar H | 2023-03-27 | Brain Pathology | |
[Vitamin D supplementation for all older people with COVID-19?]. | Mooijaart SP, Dekkers OM, Van den Bos F | 2023-03-16 | Nederlands tijdschrift voor geneeskunde | |
[Which blood pressure target for the frail older patient?]. | Claassen JAHR, Richard E, Mooijaart SP, Moll van Charante EP | 2023-03-15 | Nederlands tijdschrift voor geneeskunde | |
Course of fear of falling after hip fracture: findings from a 12-month inception cohort. | Scheffers-Barnhoorn MN, Haaksma ML, Achterberg WP, Niggebrugge AH, van der Sijp MP, van Haastregt JC, van Eijk M | 2023-03-14 | GERIATRIC MEDICINE, Hip, REHABILITATION MEDICINE | BMJ open |
Late Effects in Pediatric Allogeneic Hematopoietic Stem Cell Transplantation for Nonmalignant Diseases: Proxy- and Patient-Reported Outcomes. | Bense JE, Haverman L, von Asmuth EGJ, Louwerens M, Luijten MAJ, Stiggelbout AM, Lankester AC, de Pagter APJ | 2023-03-01 | Allogeneic hematopoietic stem cell transplantation, Health-related quality of life, Late effects, Long-term follow-up, Patient-reported outcomes, Pediatric | Transplantation and cellular therapy |
Intrinsic capacity and resilience: Taking frailty to the next level. | Hamaker M, Gijzel S, Rostoft S, van den Bos F | 2023-03-01 | Frailty, Geriatric oncology, Intrinsic capacity, Resilience | Journal of geriatric oncology |
Epigenome-Wide Association Study Reveals CpG Sites Associated with Thyroid Function and Regulatory Effects on KLF9. | Weihs A, Chaker L, Martin TC, Braun KVE, Campbell PJ, Cox SR, Fornage M, Gieger C, Grabe HJ, Grallert H, Harris SE, Kühnel B, Marioni RE, Martin NG, McCartney DL, McRae AF, Meisinger C, van Meurs JBJ, Nano J, Nauck M, Peters A, Prokisch H, Roden M, Selvin E, Beekman M, van Heemst D, Slagboom EP, Swenson BR, Tin A, Tsai PC, Uitterlinden A, Visser WE, Völzke H, Waldenberger M, Walsh JP, Köttgen A, Wilson SG, Peeters RP, Bell JT, Medici M, Teumer A | 2023-03-01 | DNA methylation, KLF9, Mendelian randomization, gene expression, thyroid function | Thyroid : official journal of the American Thyroid Association |
(Un)warranted variation in local hospital protocols for neonatal referral to the pediatrician: An explorative study in the Netherlands. | Goodarzi B, Seijmonsbergen-Schermers A, Cronie D, van Laerhoven H, van den Akker T, van Kaam AH, de Jonge A | 2023-03-01 | neonatal care, neonatel referral, pediatric consultation, protocols, variation | Birth (Berkeley, Calif.) |
“My baby is fine, no need for more clinic visits.” Facilitators and barriers for utilisation of follow-up services for children born preterm in low-resource setting: Parents’ perceptions. | Namiiro FB, Nolens B, Rujumba J, Kiguli S, Batte A, van den Akker T | 2023-03-01 | Uganda, barriers, facilitators, follow-up, preterm, qualitative study | Tropical medicine & international health : TM & IH |
Frailty and treatment decisions in older patients with vulvar cancer: A single-center cohort study. | Gans EA, Portielje JEA, Dekkers OM, de Kroon CD, van Munster BC, Derks MGM, Trompet S, van Holstein Y, Mooijaart SP, van Poelgeest MIE, van den Bos F | 2023-03-01 | Frailty, Geriatric assessment, Geriatric oncology, Treatment de-escalation, Vulvar cancer | Journal of geriatric oncology |
The impact of the mySupport advance care planning intervention on family caregivers’ perceptions of decision-making and care for nursing home residents with dementia: pretest-posttest study in six countries. | Bavelaar L, Visser M, Walshe C, Preston N, Kaasalainen S, Sussman T, Cornally N, Hartigan I, Loucka M, di Giulio P, Brazil K, Achterberg WP, van der Steen JT | 2023-03-01 | decision-making, dementia, family caregivers, nursing homes, older people | Age and ageing |
Setting your clock: associations between timing of objective physical activity and cardiovascular disease risk in the general population. | Albalak G, Stijntjes M, van Bodegom D, Jukema JW, Atsma DE, van Heemst D, Noordam R | 2023-02-14 | Chronoactivity, Coronary artery disease, Patterns, Physical activity, Stroke | European journal of preventive cardiology |
Collective Prevention of Non-Communicable Diseases in an Ageing Population with Community Care. | Kuppen R, de Leede M, Lindenberg J, van Bodegom D | 2023-02-10 | collective prevention, community care, lifestyle, public health promotion, social environment | International journal of environmental research and public health |
A Qualitative Study Exploring Professional Perspectives of a Challenging Rehabilitation Environment for Geriatric Rehabilitation. | Tijsen LMJ, Derksen EWC, Achterberg WP, Buijck BI | 2023-02-03 | care process, challenging rehabilitation environment, geriatric rehabilitation, post-acute care | Journal of clinical medicine |
Lipid-induced transcriptomic changes in blood link to lipid metabolism and allergic response. | Dekkers KF, Slieker RC, Ioan-Facsinay A, van Iterson M, Ikram MA, van Greevenbroek MMJ, Veldink JH, Franke L, Boomsma DI, Slagboom PE, Jukema JW, Heijmans BT | 2023-02-01 | Nature communications | |
The association of measures of body shape and adiposity with incidence of cardiometabolic disease from an ageing perspective. | Meulmeester FL, Willems van Dijk K, Mooijaart SP, van Heemst D, Noordam R | 2023-02-01 | Adiposity, Body composition, Cardiometabolic diseases, Geroscience, UK Biobank | GeroScience |
Post-mortem 7T MR imaging and neuropathology in middle stage juvenile-onset Huntington disease: A case report. | Bakels HS, van Duinen SG, de Bresser J, van Roon-Mom WMC, van der Weerd L, de Bot ST | 2023-02-01 | Huntington disease, Vonsattel grading system, juvenile-onset Huntington disease, magnetic resonance imaging, neuropathologic staging, neuropathology, post-mortem | Neuropathology and applied neurobiology |
Clinical outcome in patients with suspected inflammatory neuropsychiatric lupus treated with immunosuppression: an observational cohort study. | Monahan RC, Beaart-van de Voorde LJJ, Fronczek R, de Bresser J, Eikenboom J, Kloppenburg M, Middelkoop HAM, Terwindt GM, van der Wee NJA, Huizinga TWJ, Steup-Beekman GM | 2023-02-01 | lupus erythematosus, systemic, outcome assessment, healthcare, treatment | Lupus science & medicine |
Bacterial DNAemia in Older Participants and Nonagenarian Offspring and Association With Redox Biomarkers: Results From MARK-AGE Study. | Giacconi R, D'Aquila P, Malavolta M, Piacenza F, Bürkle A, Villanueva MM, Dollé MET, Jansen E, Grune T, Gonos ES, Franceschi C, Capri M, Gradinaru D, Grubeck-Loebenstein B, Sikora E, Stuetz W, Weber D, Toussaint O, Debacq-Chainiaux F, Hervonen A, Hurme M, Slagboom PE, Schön C, Bernhardt J, Breusing N, Duncan T, Passarino G, Bellizzi D, Provinciali M | 2023-01-26 | Aging, Blood bacterial DNA, Dysbiosis, Inflammation, Longevity | The journals of gerontology. Series A, Biological sciences and medical sciences |
How to Conduct International Geriatric Rehabilitation Research? | Haaksma ML, Gordon AL, van Dam van Isselt EF, Schols JMGA, Everink IHJ, Cameron ID, Becker C, Grund S, Achterberg WP | 2023-01-26 | geriatric rehabilitation, methodology, study design | Journal of clinical medicine |
Weight loss, visit-to-visit body weight variability and cognitive function in older individuals. | Zonneveld MH, Noordam R, Sabayan B, Stott DJ, Mooijaart SP, Blauw GJ, Jukema JW, Sattar N, Trompet S | 2023-01-08 | cognition, cognitive decline, cognitive function, dementia, older adults, older people, weight change, weight loss | Age and ageing |
The effect of thyroid hormone therapy on muscle function, strength and mass in older adults with subclinical hypothyroidism-an ancillary study within two randomized placebo controlled trials. | Netzer S, Chocano-Bedoya P, Feller M, Janett-Pellegri C, Wildisen L, Büchi AE, Moutzouri E, Rodriguez EG, Collet TH, Poortvliet RKE, Mc Carthy VJC, Aeberli D, Aujesky D, Westendorp R, Quinn TJ, Gussekloo J, Kearney PM, Mooijaart S, Bauer DC, Rodondi N | 2023-01-08 | levothyroxine, muscle, older people, sarcopenia, subclinical hypothyroidism | Age and ageing |
Functional connectivity in older adults-the effect of cerebral small vessel disease. | Drenth N, Foster-Dingley JC, Bertens AS, Rius Ottenheim N, van der Mast RC, Rombouts SARB, van Rooden S, van der Grond J | 2023-01-01 | ageing, cerebral small vessel disease, functional connectivity, graph theory, resting state networks | Brain communications |
Association of Torquetenovirus Viremia with Physical Frailty and Cognitive Impairment in Three Independent European Cohorts. | Giacconi R, Laffon B, Costa S, Teixeira-Gomes A, Maggi F, Macera L, Spezia PG, Piacenza F, Bürkle A, Moreno-Villanueva M, Bonassi S, Valdiglesias V, Teixeira JP, Dollé MET, Rietman ML, Jansen E, Grune T, Gonos ES, Franceschi C, Capri M, Weinberger B, Sikora E, Stuetz W, Toussaint O, Debacq-Chainiaux F, Hervonen A, Hurme M, Slagboom PE, Schön C, Bernhardt J, Breusing N, Pásaro E, Maseda A, Lorenzo-López L, Millán-Calenti JC, Provinciali M, Malavolta M | 2023-01-01 | Aging, Cognitive impairment, Inflammation, Physical frailty, Torquetenovirus | Gerontology |
Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci. | de Las Fuentes L, Schwander KL, Brown MR, Bentley AR, Winkler TW, Sung YJ, Munroe PB, Miller CL, Aschard H, Aslibekyan S, Bartz TM, Bielak LF, Chai JF, Cheng CY, Dorajoo R, Feitosa MF, Guo X, Hartwig FP, Horimoto A, Kolčić I, Lim E, Liu Y, Manning AK, Marten J, Musani SK, Noordam R, Padmanabhan S, Rankinen T, Richard MA, Ridker PM, Smith AV, Vojinovic D, Zonderman AB, Alver M, Boissel M, Christensen K, Freedman BI, Gao C, Giulianini F, Harris SE, He M, Hsu FC, Kühnel B, Laguzzi F, Li X, Lyytikäinen LP, Nolte IM, Poveda A, Rauramaa R, Riaz M, Robino A, Sofer T, Takeuchi F, Tayo BO, van der Most PJ, Verweij N, Ware EB, Weiss S, Wen W, Yanek LR, Zhan Y, Amin N, Arking DE, Ballantyne C, Boerwinkle E, Brody JA, Broeckel U, Campbell A, Canouil M, Chai X, Chen YI, Chen X, Chitrala KN, Concas MP, de Faire U, de Mutsert R, de Silva HJ, de Vries PS, Do A, Faul JD, Fisher V, Floyd JS, Forrester T, Friedlander Y, Girotto G, Gu CC, Hallmans G, Heikkinen S, Heng CK, Homuth G, Hunt S, Ikram MA, Jacobs DR, Kavousi M, Khor CC, Kilpeläinen TO, Koh WP, Komulainen P, Langefeld CD, Liang J, Liu K, Liu J, Lohman K, Mägi R, Manichaikul AW, McKenzie CA, Meitinger T, Milaneschi Y, Nauck M, Nelson CP, O'Connell JR, Palmer ND, Pereira AC, Perls T, Peters A, Polašek O, Raitakari OT, Rice K, Rice TK, Rich SS, Sabanayagam C, Schreiner PJ, Shu XO, Sidney S, Sims M, Smith JA, Starr JM, Strauch K, Tai ES, Taylor KD, Tsai MY, Uitterlinden AG, van Heemst D, Waldenberger M, Wang YX, Wei WB, Wilson G, Xuan D, Yao J, Yu C, Yuan JM, Zhao W, Becker DM, Bonnefond A, Bowden DW, Cooper RS, Deary IJ, Divers J, Esko T, Franks PW, Froguel P, Gieger C, Jonas JB, Kato N, Lakka TA, Leander K, Lehtimäki T, Magnusson PKE, North KE, Ntalla I, Penninx B, Samani NJ, Snieder H, Spedicati B, van der Harst P, Völzke H, Wagenknecht LE, Weir DR, Wojczynski MK, Wu T, Zheng W, Zhu X, Bouchard C, Chasman DI, Evans MK, Fox ER, Gudnason V, Hayward C, Horta BL, Kardia SLR, Krieger JE, Mook-Kanamori DO, Peyser PA, Province MM, Psaty BM, Rudan I, Sim X, Smith BH, van Dam RM, van Duijn CM, Wong TY, Arnett DK, Rao DC, Gauderman J, Liu CT, Morrison AC, Rotter JI, Fornage M | 2023-01-01 | cholesterol, educational attainment, genome-wide association study, lipids, meta-analysis, triglycerides | Frontiers in genetics |
Maternal and perinatal death surveillance and response: a systematic review of qualitative studies. | Willcox ML, Okello IA, Maidwell-Smith A, Tura AK, van den Akker T, Knight M | 2023-01-01 | Bulletin of the World Health Organization | |
Incidence, Indications, Risk Factors, and Outcomes of Emergency Peripartum Hysterectomy Worldwide: A Systematic Review and Meta-analysis. | Kallianidis AF, Rijntjes D, Brobbel C, Dekkers OM, Bloemenkamp KWM, van den Akker T | 2023-01-01 | Obstetrics and gynecology | |
Primary Effusion Lymphoma in an HIV-Negative Patient with Chronic Myeloid Leukemia Treated with Dasatinib. | SahBandar IN, Sy CB, van den Akker T, Kim D, Geyer JT, Chadburn A, Cesarman E, Inghirami G, Allan JN, Siddiqui MT, Ouseph MM | 2023-01-01 | Chronic myeloid leukemia, Dasatinib, Lymphoma, Primary effusion lymphoma | Pathobiology : journal of immunopathology, molecular and cellular biology |
Receiving antenatal care components and associated factors in Northwestern Tanzania. | Massenga J, Jeremiah K, Kitinya W, Kim YM, van Roosmalen J, van den Akker T | 2023-01-01 | PloS one | |
Correction: No increase in use of hospitals for childbirth in Tanzania over 25 years: Accumulation of inequity among poor, rural, high parity women. | Straneo M, Beňová L, van den Akker T, Pembe AB, Smekens T, Hanson C | 2023-01-01 | PLOS global public health | |
The more, the better: influence of family planning discussions during the maternal, newborn and child health continuum of care on postpartum contraceptive uptake and method type among young women in Ethiopia. | Calhoun LM, Winston J, Beňová L, Speizer IS, Delvaux T, Shiferaw S, Seme A, Karp C, Zimmerman L, van den Akker T | 2023-01-01 | adolescent, continuum of care, contraception, counseling, family planning, integration, postpartum, prenatal care, youth | Gates open research |
The Ethiopian Anesthetist Licensing Examination and Associated Improvement in in-School Student Performance: A Retrospective Study. | Asemu YM, Yigzaw T, Ayalew F, Akalu L, Scheele F, van den Akker T | 2023-01-01 | anesthesia, anesthetist, associate clinician, licensing examination, non-physician | Advances in medical education and practice |
Ethiopian Anesthetist Licensing Examination: A Qualitative Study of Concerns and Unintended Consequences. | Asemu YM, Yigzaw T, Ayalew F, Akalu L, Scheele F, van den Akker T | 2023-01-01 | anesthesia, anesthetist, associate clinician, licensing examination, non-physician | Advances in medical education and practice |
Association of low blood pressure and falls: An analysis of data from the Leiden 85-plus Study. | Röthlisberger D, Jungo KT, Bütikofer L, Poortvliet RKE, Gussekloo J, Streit S | 2023-01-01 | PloS one | |
Carotid Artery Stenosis and Progression of Hemispheric Brain Atrophy: The SMART-MR Study. | Ghaznawi R, Rissanen I, de Bresser J, Kuijf HJ, Zuithoff NPA, Hendrikse J, Geerlings MI | 2023-01-01 | Brain atrophy, Carotid artery stenosis, Cohort studies, MRI | Cerebrovascular diseases (Basel, Switzerland) |
Postoperative delirium is associated with grey matter brain volume loss. | Kant IMJ, de Bresser J, van Montfort SJT, Witkamp TD, Walraad B, Spies CD, Hendrikse J, van Dellen E, Slooter AJC | 2023-01-01 | brain infarcts, brain volume, delirium, encephalopathy, grey matter | Brain communications |
The prevalence and severity of fatigue in meningioma patients and its association with patient-, tumor- and treatment-related factors. | Quach KT, Dirven L, Vingerhoed AM, de Bresser J, Dammers R, Bos EM, Moojen WA, Peul WC, Taphoorn MJB, Zamanipoor Najafabadi AH, van Furth WR | 2023-01-01 | central nervous system tumor, fatigue, long-term, meningioma, patient-reported outcome | Neuro-oncology advances |
Study protocol of IMAGINE-HD: Imaging iron accumulation and neuroinflammation with 7T-MRI + CSF in Huntington’s disease. | van de Zande NA, Bulk M, Najac C, van der Weerd L, de Bresser J, Lewerenz J, Ronen I, de Bot ST | 2023-01-01 | Biomarkers, CSF, Huntington’s disease, Iron accumulation, MRI, Neuroinflammation | NeuroImage. Clinical |
White matter changes measured by multi-component MR Fingerprinting in multiple sclerosis. | Nagtegaal MA, Hermann I, Weingärtner S, Martinez-Heras E, Solana E, Llufriu S, Gass A, Poot DHJ, van Osch MJP, Vos FM, de Bresser J | 2023-01-01 | MR Fingerprinting, Multi-component analysis, Multiple Sclerosis, Quantitative MRI, White matter damage | NeuroImage. Clinical |
MRI phenotypes of glioblastomas early after treatment are suggestive of overall patient survival. | Schmitz-Abecassis B, Dirven L, Jiang J, Keller JA, Croese RJI, van Dorth D, Ghaznawi R, Kant IMJ, Taphoorn MJB, van Osch MJP, Koekkoek JAF, de Bresser J | 2023-01-01 | MRI, glioblastoma, perfusion, tumor progression | Neuro-oncology advances |
A Qualitative Study Exploring Rehabilitant and Informal Caregiver Perspectives of a Challenging Rehabilitation Environment for Geriatric Rehabilitation. | Tijsen LMJ, Derksen EWC, Achterberg WP, Buijck BI | 2023-01-01 | challenging rehabilitation environment, geriatric rehabilitation, informal caregiver, rehabilitant | Journal of patient experience |
Supporting Resilience of Older Adults with Cognitive Decline Requires a Multi-Level System Approach. | Peeters G, Kok A, de Bruin SR, van Campen C, Graff M, Nieuwboer M, Huisman M, van Munster B, van der Zee EA, Kas MJ, Perry M, Gerritsen DL, Vreede-Chabot E, The AM, van Hout H, Bakker FC, Achterberg WP, van der Steen JT, Smits C, Melis R, Olde Rikkert M | 2023-01-01 | Cognition, Dementia, Old age, Resilience, Socio-ecological system | Gerontology |
The effect of garden use on quality of life and behavioral and psychological symptoms of dementia in people living with dementia in nursing homes: a systematic review. | van der Velde-van Buuringen M, Hendriks-van der Sar R, Verbeek H, Achterberg WP, Caljouw MAA | 2023-01-01 | behavioral and psychological symptoms of dementia, dementia, garden use, nursing homes, quality of life, systematic review | Frontiers in psychiatry |
Scaling up Locally Adapted Clinical Practice Guidelines for Improving Childbirth Care in Tanzania: A Protocol for Programme Theory and Qualitative Methods of the PartoMa Scale-up Study. | Sørensen JB, Housseine N, Maaløe N, Bygbjerg IC, Pinkowski Tersbøl B, Konradsen F, Sequeira Dmello B, van Den Akker T, van Roosmalen J, Mookherji S, Siaity E, Osaki H, Khamis RS, Kujabi ML, John TW, Wolf Meyrowitsch D, Mbekenga C, Skovdal M, L Kidanto H | 2022-12-31 | Practice theory, co-creation, intervention, obstetrics, respectful maternity care | Global health action |
Scaling up context-tailored clinical guidelines and training to improve childbirth care in urban, low-resource maternity units in Tanzania: A protocol for a stepped-wedged cluster randomized trial with embedded qualitative and economic analyses (The PartoMa Scale-Up Study). | Maaløe N, Housseine N, Sørensen JB, Obel J, Sequeira DMello B, Kujabi ML, Osaki H, John TW, Khamis RS, Muniro ZSS, Nkungu DJ, Pinkowski Tersbøl B, Konradsen F, Mookherji S, Mbekenga C, Meguid T, van Roosmalen J, Bygbjerg IC, van den Akker T, Jensen AK, Skovdal M, L Kidanto H, Wolf Meyrowitsch D | 2022-12-31 | Africa, Obstetrics, co-creation, cost-effectiveness, de-colonizing, intervention, low dose high frequency training, perinatal death, programme theory, respectful maternity care, stillbirth, urbanization | Global health action |
Strategies to Increase Willingness to Receive a COVID-19 Vaccine among Nursing Home Staff. | van Tol LS, Meester W, Caljouw MAA, Achterberg WP | 2022-12-31 | COVID-19, nursing homes, staff, vaccination | Infectious disease reports |
Clustered Mendelian randomization analyses identify distinct and opposing pathways in the association between genetically influenced insulin-like growth factor-1 and type 2 diabetes mellitus. | Wang W, Tesfay EB, van Klinken JB, Willems van Dijk K, Bartke A, van Heemst D, Noordam R | 2022-12-13 | Clustered Mendelian randomization analysis, Mendelian randomization analysis, cohort studies, insulin-like growth factor-1, type 2 diabetes | International journal of epidemiology |
Tract-based white matter hyperintensity patterns in patients with systemic lupus erythematosus using an unsupervised machine learning approach. | Rumetshofer T, Inglese F, de Bresser J, Mannfolk P, Strandberg O, Jönsen A, Bengtsson A, Nilsson M, Knutsson L, Lätt J, Steup-Beekman GM, Huizinga TWJ, van Buchem MA, Ronen I, Sundgren PC | 2022-12-09 | Scientific reports | |
Should we take Mum to market? Quality and funding in the care home sector. | Allan S, Irvine L, Achterberg WP | 2022-12-05 | care home, older people, ownership, quality of care | Age and ageing |
Agreement between nicotine metabolites in blood and self-reported smoking status: The Netherlands Epidemiology of Obesity study. | Folpmers S, Mook-Kanamori DO, de Mutsert R, Rosendaal FR, Willems van Dijk K, van Heemst D, Noordam R, le Cessie S | 2022-12-01 | Agreement, Nicotine metabolites, Self reported smoking status, Smoking | Addictive behaviors reports |
Thyroid antibodies and levothyroxine effects in subclinical hypothyroidism: A pooled analysis of two randomized controlled trials. | Lyko C, Blum MR, Abolhassani N, Stuber MJ, Del Giovane C, Feller M, Moutzouri E, Oberle J, Jungo KT, Collet TH, den Elzen WPJ, Poortvliet RKE, Du Puy RS, Dekkers OM, Trompet S, Jukema JW, Aujesky D, Quinn T, Westendorp R, Kearney PM, Gussekloo J, Van Heemst D, Mooijaart SP, Bauer DC, Rodondi N | 2022-12-01 | autoimmune thyroid disease, levothyroxine treatment, subclinical hypothyroidism | Journal of internal medicine |
Vascular disease and apathy symptoms in the very old: A cross-sectional and longitudinal meta-analysis of individual participant data. | van der Klei VMGTH, Poortvliet RKE, Bogaerts JMK, Blom JW, Mooijaart SP, Teh R, Muru-Lanning M, Palapar L, Kingston A, Robinson L, Kerse N, Gussekloo J | 2022-12-01 | atherosclerosis, meta-analysis, older people, prospective, vascular apathy | International journal of geriatric psychiatry |
White matter hyperintensity shape is associated with cognitive functioning – the SMART-MR study. | Zwartbol MHT, Ghaznawi R, Jaarsma-Coes M, Kuijf H, Hendrikse J, de Bresser J, Geerlings MI | 2022-12-01 | Aging, Cognitive functioning, MRI, SMART-MR study, Shape analysis, White matter hyperintensities | Neurobiology of aging |
Systematic review of measurement properties of the Canadian Occupational Performance Measure in geriatric rehabilitation. | de Waal MWM, Haaksma ML, Doornebosch AJ, Meijs R, Achterberg WP | 2022-12-01 | Aged, COPM, Geriatric rehabilitation, Reliability, Responsiveness, Validity | European geriatric medicine |
Post-acute COVID-19 geriatric rehabilitation : A European perspective. | van Dam van Isselt EF, Schols JMGA, Gordon AL, Achterberg WP, van Haastregt J, Becker C, Grund S, Bauer JM | 2022-12-01 | Coronavirus disease 2019, Older patients, Preparedness, Rehabilitation paradox, Review | Zeitschrift fur Gerontologie und Geriatrie |
Antioxidant Supplementation in Oxidative Stress-Related Diseases: What Have We Learned from Studies on Alpha-Tocopherol? | Meulmeester FL, Luo J, Martens LG, Mills K, van Heemst D, Noordam R | 2022-11-24 | antioxidant supplementation, oxidative stress, reactive oxygen species, α-tocopherol | Antioxidants (Basel, Switzerland) |
[Pain and neurocognitive disorders: current state of the art and remaining challenges]. | Achterberg WP, de Waal MWM, Cheuk-A-Lam-Balrak JMJJ, Crutzen-Braaksma P, van Dalen-Kok A, van Dam P, de Knegt NC, van Kooten J, Lobbezoo F, Smaling HJA, Sprenger GP, van der Steen JT, de Vries CNJ, Zwakhalen SMG, Smalbrugge M, Oosterman JM | 2022-11-24 | Assessment, Cognitive impairment, Dementia, Pain, Treatment | Tijdschrift voor gerontologie en geriatrie |
Evaluating the feasibility, experiences, facilitators of and barriers to carers and volunteers delivering Namaste Care to people with dementia in their own home: a qualitative interview study in the UK and the Netherlands. | Haaksma ML, O'Driscoll C, Joling KJ, Achterberg WP, Francke AL, van der Steen JT, Smaling HJA | 2022-11-14 | Namaste Care, carers, community-dwelling, dementia, multisensory | BMJ open |
Factors associated with formal and informal resource utilization in nursing home patients with and without dementia: cross-sectional analyses from the COSMOS trial. | Vislapuu M, Berge LI, Angeles RC, Kjerstad E, Mannseth J, Achterberg WP, Husebo BS | 2022-11-02 | Dementia, Formal care, Informal care, Nursing home | BMC health services research |
Self-perceived functioning and (instrumental) activities of daily living questionnaires after a hip fracture: Do they tell the same story? | Ravensbergen WM, Timmer IL, Gussekloo J, Blom JW, van Eijk M, Achterberg WP, Evers AWM, van Dijk S, Drewes YM | 2022-11-02 | (instrumental) activities of daily living, hip fracture, older people, qualitative research, self-perceived functioning | Age and ageing |
A longitudinal analysis of nosocomial bloodstream infections among preterm neonates. | Jansen SJ, van der Hoeven A, van den Akker T, Veenhof M, von Asmuth EGJ, Veldkamp KE, Rijken M, van der Beek M, Bekker V, Lopriore E | 2022-11-01 | Central-lines, Epidemiology, Hospital-acquired infections, Neonates | European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology |
Labor augmentation with oxytocin in low- and lower-middle-income countries: a systematic review and meta-analysis. | Kujabi ML, Mikkelsen E, Housseine N, Obel J, D'Mello BS, Meyrowitsch DW, Hussein K, Schroll JB, Konradsen F, van Roosmalen J, van den Akker T, Maaløe N | 2022-11-01 | Apgar score, birth asphyxia, childbirth, clinical guidelines, low- and lower-middle-income countries, low-resource setting, neonatal encephalopathy, neonatal mortality, neonatal resuscitation, oxytocin augmentation, partograph, perinatal mortality, prolonged labor, stillbirths | AJOG global reports |
Metabolomic profiles predict individual multidisease outcomes. | Buergel T, Steinfeldt J, Ruyoga G, Pietzner M, Bizzarri D, Vojinovic D, Upmeier Zu Belzen J, Loock L, Kittner P, Christmann L, Hollmann N, Strangalies H, Braunger JM, Wild B, Chiesa ST, Spranger J, Klostermann F, van den Akker EB, Trompet S, Mooijaart SP, Sattar N, Jukema JW, Lavrijssen B, Kavousi M, Ghanbari M, Ikram MA, Slagboom E, Kivimaki M, Langenberg C, Deanfield J, Eils R, Landmesser U | 2022-11-01 | Nature medicine | |
PLIS: A metabolomic response monitor to a lifestyle intervention study in older adults. | Bogaards FA, Gehrmann T, Beekman M, van den Akker EB, van de Rest O, Hangelbroek RWJ, Noordam R, Mooijaart SP, de Groot LCPGM, Reinders MJT, Slagboom PE | 2022-11-01 | bioinformatics, healthy ageing, lifestyle intervention, machine learning, metabolomics, response monitor | FASEB journal : official publication of the Federation of American Societies for Experimental Biology |
Subclinical thyroid dysfunction and incident diabetes: a systematic review and an individual participant data analysis of prospective cohort studies. | Alwan H, Villoz F, Feller M, Dullaart RPF, Bakker SJL, Peeters RP, Kavousi M, Bauer DC, Cappola AR, Yeap BB, Walsh JP, Brown SJ, Ceresini G, Ferrucci L, Gussekloo J, Trompet S, Iacoviello M, Moon JH, Razvi S, Bensenor IM, Azizi F, Amouzegar A, Valdés S, Colomo N, Wareham NJ, Jukema JW, Westendorp RGJ, Kim KW, Rodondi N, Del Giovane C | 2022-11-01 | European journal of endocrinology | |
Accuracy and repeatability of joint sparsity multi-component estimation in MR Fingerprinting. | Nunez-Gonzalez L, Nagtegaal MA, Poot DHJ, de Bresser J, van Osch MJP, Hernandez-Tamames JA, Vos FM | 2022-11-01 | Accuracy, Brain, Multi-component MR Fingerprinting, Quantitative MRI, Repeatability, Segmentation | NeuroImage |
Intraoperative electrocorticography using high-frequency oscillations or spikes to tailor epilepsy surgery in the Netherlands (the HFO trial): a randomised, single-blind, adaptive non-inferiority trial. | Zweiphenning W, Klooster MAV', van Klink NEC, Leijten FSS, Ferrier CH, Gebbink T, Huiskamp G, van Zandvoort MJE, van Schooneveld MMJ, Bourez M, Goemans S, Straumann S, van Rijen PC, Gosselaar PH, van Eijsden P, Otte WM, van Diessen E, Braun KPJ, Zijlmans M | 2022-11-01 | The Lancet. Neurology | |
Time Trends in Treatment Strategies and Survival of Older versus Younger Patients with Synchronous Metastasised Melanoma-A Population-Based Study in the Netherlands Cancer Registry. | van der Ziel D, Derks MGM, Kapiteijn E, Bastiaannet E, Louwman M, van den Bos F, Mooijaart SP, Portielje JEA, de Glas NA | 2022-10-07 | geriatric oncology, immunotherapy, melanoma, older adults, survival | Cancers |
Common Genetic Variation and Age of Onset of Anorexia Nervosa. | Watson HJ, Thornton LM, Yilmaz Z, Baker JH, Coleman JRI, Adan RAH, Alfredsson L, Andreassen OA, Ask H, Berrettini WH, Boehnke M, Boehm I, Boni C, Buehren K, Bulant J, Burghardt R, Chang X, Cichon S, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, de Zwaan M, Dedoussis G, DeSocio JE, Dick DM, Dikeos D, Dina C, Djurovic S, Dmitrzak-Weglarz M, Docampo-Martinez E, Duriez P, Egberts K, Ehrlich S, Eriksson JG, Escaramís G, Esko T, Estivill X, Farmer A, Fernández-Aranda F, Fichter MM, Föcker M, Foretova L, Forstner AJ, Frei O, Gallinger S, Giegling I, Giuranna J, Gonidakis F, Gorwood P, Gratacòs M, Guillaume S, Guo Y, Hakonarson H, Hauser J, Havdahl A, Hebebrand J, Helder SG, Herms S, Herpertz-Dahlmann B, Herzog W, Hinney A, Hübel C, Hudson JI, Imgart H, Jamain S, Janout V, Jiménez-Murcia S, Jones IR, Julià A, Kalsi G, Kaminská D, Kaprio J, Karhunen L, Kas MJH, Keel PK, Kennedy JL, Keski-Rahkonen A, Kiezebrink K, Klareskog L, Klump KL, Knudsen GPS, La Via MC, Le Hellard S, Leboyer M, Li D, Lilenfeld L, Lin B, Lissowska J, Luykx J, Magistretti P, Maj M, Marsal S, Marshall CR, Mattingsdal M, Meulenbelt I, Micali N, Mitchell KS, Monteleone AM, Monteleone P, Myers R, Navratilova M, Ntalla I, O'Toole JK, Ophoff RA, Padyukov L, Pantel J, Papežová H, Pinto D, Raevuori A, Ramoz N, Reichborn-Kjennerud T, Ricca V, Ripatti S, Ripke S, Ritschel F, Roberts M, Rotondo A, Rujescu D, Rybakowski F, Scherag A, Scherer SW, Schmidt U, Scott LJ, Seitz J, Silén Y, Šlachtová L, Slagboom PE, Slof-Op 't Landt MCT, Slopien A, Sorbi S, Świątkowska B, Tortorella A, Tozzi F, Treasure J, Tsitsika A, Tyszkiewicz-Nwafor M, Tziouvas K, van Elburg AA, van Furth EF, Walton E, Widen E, Zerwas S, Zipfel S, Bergen AW, Boden JM, Brandt H, Crawford S, Halmi KA, Horwood LJ, Johnson C, Kaplan AS, Kaye WH, Mitchell JE, Olsen CM, Pearson JF, Pedersen NL, Strober M, Werge T, Whiteman DC, Woodside DB, Gordon S, Maguire S, Larsen JT, Parker R, Petersen LV, Jordan J, Kennedy M, Wade TD, Birgegård A, Lichtenstein P, Landén M, Martin NG, Mortensen PB, Breen G, Bulik CM | 2022-10-01 | Age of onset, Anorexia nervosa, Early-onset, GWAS, Genetic risk score, Genetics, Menarche, Mendelian randomization, Puberty | Biological psychiatry global open science |
Assessment of the bi-directional relationship between blood mitochondrial DNA copy number and type 2 diabetes mellitus: a multivariable-adjusted regression and Mendelian randomisation study. | Wang W, Luo J, Willems van Dijk K, Hägg S, Grassmann F, T Hart LM, van Heemst D, Noordam R | 2022-10-01 | Mendelian randomisation, Mitochondrial DNA copy number, Prospective analyses, Type 2 diabetes mellitus | Diabetologia |
Predictors of HIV Among 1 Million Clients in High-Risk Male Populations in Tanzania. | Mbita G, Komba AN, Casalini C, Bazant E, Curran K, Christensen A, Nyato D, Kim YM, Reed J, Makyao N, Kategile U, Conserve DF, Faini D, van Roosmalen J, van den Akker T | 2022-10-01 | Male client of female sex workers, Men living in areas with high risk of HIV, Men who have sex with men, Sexually transmitted infections, Tanzania | AIDS and behavior |
Physiological-based cord clamping in very preterm infants: the Aeration, Breathing, Clamping 3 (ABC3) trial-study protocol for a multicentre randomised controlled trial. | Knol R, Brouwer E, van den Akker T, DeKoninck PLJ, Lopriore E, Onland W, Vermeulen MJ, van den Akker-van Marle ME, van Bodegom-Vos L, de Boode WP, van Kaam AH, Reiss IKM, Polglase GR, Hutten GJ, Prins SA, Mulder EEM, Hulzebos CV, van Sambeeck SJ, van der Putten ME, Zonnenberg IA, Hooper SB, Te Pas AB | 2022-10-01 | Cord clamping, Physiological-based cord clamping, Preterm infants, Randomised clinical trial, Study protocol | Trials |
Delirium in older COVID-19 patients: Evaluating risk factors and outcomes. | Kroon B, Beishuizen SJE, van Rensen IHT, Barten DG, Mehagnoul-Schipper JJ, van der Bol JM, Ellerbroek JLJ, Festen J, van de Glind EMM, Hempenius L, van der Jagt M, Jansen SWM, van der Linden CJM, Mooijaart SP, van Munster BC, Oosterwijk LLE, Smit L, Urlings-Strop LC, Willems HC, Mattace-Raso FUS, Polinder-Bos HA | 2022-10-01 | CFS, COVID‐19, delirium, mortality | International journal of geriatric psychiatry |
Change in Advance Care Plans of Nursing Home Residents With Dementia and Pneumonia: Secondary Analysis of Randomized Controlled Trial Data. | Bavelaar L, Visser M, Schlicksupp P, Tilburgs B, van der Maaden T, Achterberg WP, van der Steen JT | 2022-10-01 | Advance care planning, dementia, nursing homes, pneumonia, shared decision making | Journal of the American Medical Directors Association |
Long-term effects of selective fetal growth restriction (LEMON): a cohort study of neurodevelopmental outcome in growth discordant identical twins in the Netherlands. | Groene SG, Stegmeijer KJJ, Tan RNGB, Steggerda SJ, Haak MC, Slaghekke F, Roest AAW, Heijmans BT, Lopriore E, van Klink JMM | 2022-09-01 | The Lancet. Child & adolescent health | |
Network structure of time-varying depressive symptoms through dynamic time warp analysis in late-life depression. | van Zelst DCR, Veltman EM, Rhebergen D, Naarding P, Kok AAL, Ottenheim NR, Giltay EJ | 2022-09-01 | Inventory of Depressive Symptomatology, cluster analysis, dynamic time warp analysis, late-life depression, major depressive disorder, network analysis, time series | International journal of geriatric psychiatry |
Lessons learned from the perinatal audit of uterine rupture in the Netherlands: A mixed-method study. | Rosman AN, van Dillen J, Zwart J, Overtoom E, Schaap T, Bloemenkamp K, van den Akker T | 2022-09-01 | audit, maternal near miss, perinatal mortality, severe maternal morbidity, trial of labor after cesarean section, uterine rupture | Health science reports |
Experiences of a dedicated Heart and Maternal Health Service providing multidisciplinary care to pregnant women with cardiac disease in a tertiary centre in Namibia. | Heemelaar S, Agapitus N, van den Akker T, Stekelenburg J, Mackenzie S, Hugo-Hamman C, Auala T | 2022-09-01 | Namibia, cardiac disease in pregnancy, cardiomyopathy, maternal mortality, pregnancy complications, rheumatic heart disease, sub-Saharan Africa | Tropical medicine & international health : TM & IH |
Multimodal tract-based MRI metrics outperform whole brain markers in determining cognitive impact of small vessel disease-related brain injury. | De Luca A, Kuijf H, Exalto L, Thiebaut de Schotten M, Biessels GJ | 2022-09-01 | Cerebral small vessel disease, Cognition, Diffusion MRI, Fiber tractography, Neural network | Brain structure & function |
Disentangling the varying associations between systolic blood pressure and health outcomes in the very old: an individual patient data meta-analysis. | Bogaerts JMK, Poortvliet RKE, van der Klei VMGTH, Achterberg WP, Blom JW, Teh R, Muru-Lanning M, Kerse N, Rolleston A, Jagger C, Kingston A, Robinson L, Arai Y, Shikimoto R, Gussekloo J | 2022-09-01 | Journal of hypertension | |
Every maternal near-miss counts: Need for a national audit in South Africa? A mixed-methods study. | Heitkamp A, Suh J, Gebhardt S, Van Roosmalen J, Murray LR, De Vries JI, Van den Akker T, Theron G | 2022-08-30 | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde | |
The global use of the International Classification of Diseases to Perinatal Mortality (ICD-PM): A systematic review. | Prüst ZD, Kodan LR, van den Akker T, Bloemenkamp KW, Rijken MJ, Verschueren KJ | 2022-08-17 | Journal of global health | |
The association between continuous ambulatory heart rate, heart rate variability, and 24-h rhythms of heart rate with familial longevity and aging. | Wiersema JM, Kamphuis AEP, Rohling JHT, Kervezee L, Akintola AA, Jansen SW, Slagboom PE, van Heemst D, van der Spoel E | 2022-08-16 | aging, continuous ambulatory measurements, heart rate, heart rate variability, longevity | Aging |
Association between fat-soluble vitamins and self-reported health status: a cross-sectional analysis of the MARK-AGE cohort. | Stokes CS, Weber D, Wagenpfeil S, Stuetz W, Moreno-Villanueva M, Dollé MET, Jansen E, Gonos ES, Bernhardt J, Grubeck-Loebenstein B, Fiegl S, Sikora E, Toussaint O, Debacq-Chainiaux F, Capri M, Hervonen A, Slagboom PE, Breusing N, Frank J, Bürkle A, Franceschi C, Grune T | 2022-08-14 | Micronutrients, Plasma, Retinol, Vitamin D, α-tocopherol | The British journal of nutrition |
MiMIR: R-shiny application to infer risk factors and endpoints from Nightingale Health’s 1H-NMR metabolomics data. | Bizzarri D, Reinders MJT, Beekman M, Slagboom PE, van den Akker EB | 2022-08-02 | Bioinformatics (Oxford, England) | |
Systemic inflammatory markers in relation to cognitive function and measures of brain atrophy: a Mendelian randomization study. | Luo J, le Cessie S, Blauw GJ, Franceschi C, Noordam R, van Heemst D | 2022-08-01 | Cerebral cortex, Cognitive function, Cytokines, Hippocampal volume, Inflammation | GeroScience |
The association between mitochondrial DNA abundance and stroke: A combination of multivariable-adjusted survival and Mendelian randomization analyses. | Martens LG, Luo J, Wermer MJH, Willems van Dijk K, Hägg S, Grassmann F, Noordam R, van Heemst D | 2022-08-01 | Cardiovascular diseases, Hemorrhagic stroke, Ischemic stroke, Mendelian randomization, Mitochondrial DNA copy numbers, Mitochondrial function, Reactive oxygen species | Atherosclerosis |
Bone geometry in older adults with subclinical hypothyroidism upon levothyroxine therapy: A nested study within a randomized placebo controlled trial. | Büchi AE, Feller M, Netzer S, Blum MR, Gonzalez Rodriguez E, Collet TH, Del Giovane C, van Heemst D, Quinn T, Kearney PM, Westendorp RGJ, Gussekloo J, Mooijaart SP, Hans D, Bauer DC, Rodondi N, Aeberli D | 2022-08-01 | Bone geometry, Levothyroxine, Peripheral quantitative computational tomography, Subclinical hypothyoroidism, Volumetric bone density | Bone |
Metabolomic predictors of phenotypic traits can replace and complement measured clinical variables in population-scale expression profiling studies. | Niehues A, Bizzarri D, Reinders MJT, Slagboom PE, van Gool AJ, van den Akker EB, 't Hoen PAC | 2022-07-31 | Clinical surrogates, Expression profiling, Meta-analysis, Metabolomics, Multi-omics, Population cohort study, Predictors, Surrogate outcomes, Surrogates, Transcriptomics | BMC genomics |
Survival of patients who opt for dialysis versus conservative care: a systematic review and meta-analysis. | Voorend CGN, van Oevelen M, Verberne WR, van den Wittenboer ID, Dekkers OM, Dekker F, Abrahams AC, van Buren M, Mooijaart SP, Bos WJW | 2022-07-26 | conservative care, dialysis, end-stage kidney disease, mortality, systematic review | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association |
A cluster of blood-based protein biomarkers reflecting coagulation relates to the burden of cerebral small vessel disease. | Kuipers S, Overmars LM, van Es B, de Bresser J, Bron EE, Hoefer IE, Kappelle LJ, Teunissen CE, Biessels GJ, Haitjema S | 2022-07-01 | Biomarkers, cerebral small vessel diseases, coagulation, proteins, unsupervised cluster analysis | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism |
Preferences for in-kind and in-cash home care insurance. | de Bresser J, Knoef M, van Ooijen R | 2022-07-01 | Discrete choice experiment, Health expectations, Home care, Long-term care insurance, Saving motives, Willingness to pay | Journal of health economics |
Coping strategies of older adults with a recent hip fracture within inpatient geriatric rehabilitation. | Scheffers-Barnhoorn MN, Sharma-Virk M, van Balen R, van Eijk M, Achterberg WP | 2022-07-01 | 2016), Coping (strategies), Netherlands Trial Register: NTR5695 (March 7, geriatric rehabilitation, hip fracture | Aging & mental health |
From Warkworth House to the 21st century care homes: progress marked by persistent challenges. | Gordon AL, Spilsbury K, Achterberg WP, Adams R, Jones L, Goodman C | 2022-07-01 | care homes, minimum datasets, older people, primary care | Age and ageing |
Implementing a Personalized Integrated Stepped-Care Method (STIP-Method) to Prevent and Treat Neuropsychiatric Symptoms in Persons With Dementia in Nursing Homes: Protocol for a Mixed Methods Study. | Verstraeten HMF, Ziylan C, Gerritsen DL, Huijsman R, Nakanishi M, Smalbrugge M, van der Steen JT, Zuidema SU, Achterberg WP, Bakker TJEM | 2022-06-22 | caregiver, dementia, implementation, neuropsychiatric symptoms, nursing homes, psychosocial intervention | JMIR research protocols |
Classical risk factors for primary coronary artery disease from an aging perspective through Mendelian Randomization. | Jansen SA, Huiskens B, Trompet S, Jukema J, Mooijaart SP, Willems van Dijk K, van Heemst D, Noordam R | 2022-06-01 | Aging, Coronary artery disease, LDL cholesterol, Mendelian Randomization, Risk factors | GeroScience |
Microinfarcts in the Deep Gray Matter on 7T MRI: Risk Factors, MRI Correlates, and Relation to Cognitive Functioning-The SMART-MR Study. | Ghaznawi R, Zwartbol MHT, de Bresser J, Kuijf HJ, Vincken KL, Rissanen I, Geerlings MI, Hendrikse J | 2022-06-01 | AJNR. American journal of neuroradiology | |
Prevalence, risk factors, and long-term outcomes of cerebral ischemia in hospitalized COVID-19 patients – study rationale and protocol of the CORONIS study: A multicentre prospective cohort study. | van Lith TJ, Sluis WM, Wijers NT, Meijer FJ, Kamphuis-van Ulzen K, de Bresser J, Dankbaar JW, van den Heuvel FM, Antoni ML, Mulders-Manders CM, de Mast Q, van de Veerdonk FL, Klok FA, Tuladhar AM, Cannegieter SC, Wermer MJ, van der Worp HB, Huisman MV, de Leeuw FE | 2022-06-01 | COVID-19, SARS-CoV-2, ischemic stroke, silent cerebral ischemia | European stroke journal |
Neuropsychiatric systemic lupus erythematosus is associated with a distinct type and shape of cerebral white matter hyperintensities. | Inglese F, Jaarsma-Coes MG, Steup-Beekman GM, Monahan R, Huizinga T, van Buchem MA, Ronen I, de Bresser J | 2022-05-30 | MRI, SLE, brain, white matter hyperintensity | Rheumatology (Oxford, England) |
Distancing Measures and Challenges Discussed by COVID-19 Outbreak Teams of Dutch Nursing Homes: The COVID-19 MINUTES Study. | van Tol LS, Smaling HJA, Meester W, Janus SIM, Zuidema SU, de Waal MWM, Caljouw MAA, Achterberg WP | 2022-05-27 | COVID-19, distancing, infection prevention and control, isolation, nursing homes, qualitative | International journal of environmental research and public health |
Linking a peer coach physical activity intervention for older adults to a primary care referral scheme. | van de Vijver PL, Schalkwijk FH, Numans ME, Slaets JPJ, van Bodegom D | 2022-05-17 | Exercise referral, Lifestyle, Peer coaching, Physical activity, Primary care | BMC primary care |
No Effect of Levothyroxine on Hemoglobin in Older Adults With Subclinical Hypothyroidism: Pooled Results From 2 Randomized Controlled Trials. | Du Puy RS, Poortvliet RKE, Mooijaart SP, Stott DJ, Quinn T, Sattar N, Westendorp RGJ, Kearney PM, McCarthy VJC, Byrne S, Rodondi N, Baretella O, Collet TH, van Heemst D, Dekkers OM, Jukema JW, Smit JWA, Gussekloo J, den Elzen WPJ | 2022-05-17 | RCT, anemia, older adults, subclinical hypothyroidism, thyroid | The Journal of clinical endocrinology and metabolism |
Prospective individual patient data meta-analysis of two randomized trials on convalescent plasma for COVID-19 outpatients. | Millat-Martinez P, Gharbharan A, Alemany A, Rokx C, Geurtsvankessel C, Papageorgiou G, van Geloven N, Jordans C, Groeneveld G, Swaneveld F, van der Schoot E, Corbacho-Monné M, Ouchi D, Piccolo Ferreira F, Malchair P, Videla S, García García V, Ruiz-Comellas A, Ramírez-Morros A, Rodriguez Codina J, Amado Simon R, Grifols JR, Blanco J, Blanco I, Ara J, Bassat Q, Clotet B, Baro B, Troxel A, Zwaginga JJ, Mitjà O, Rijnders BJA | 2022-05-11 | Nature communications | |
Depression and Inflammatory Bowel Disease: A Bidirectional Two-sample Mendelian Randomization Study. | Luo J, Xu Z, Noordam R, van Heemst D, Li-Gao R | 2022-05-10 | Depression, Mendelian randomization, inflammatory bowel disease | Journal of Crohn's & colitis |
Visual impairment as a predictor for deterioration in functioning: the Leiden 85-plus Study. | Verbeek E, Drewes YM, Gussekloo J | 2022-05-06 | Cohort study, Functioning, Mortality, Older adults, Prediction, Quality of life, Visual impairment | BMC geriatrics |
Assessment of the appropriateness of cardiovascular preventive medication in older people: using the RAND/UCLA Appropriateness Method. | van der Ploeg MA, Poortvliet RKE, Achterberg WP, Mooijaart SP, Gussekloo J, Drewes YM | 2022-05-05 | Cardiovascular diseases, Clinical decision-making, Drug therapy, Geriatrics, Preventive medicine | BMC geriatrics |
Deficits in Geriatric Assessment Associate With Disease Activity and Burden in Older Patients With Inflammatory Bowel Disease. | Asscher VER, Waars SN, van der Meulen-de Jong AE, Stuyt RJL, Baven-Pronk AMC, van der Marel S, Jacobs RJ, Haans JJL, Meijer LJ, Klijnsma-Slagboom JD, Duin MH, Peters MER, Lee-Kong FVYL, Provoost NE, Tijdeman F, van Dijk KT, Wieland MWM, Verstegen MGM, van der Meijs ME, Maan ADI, van Deudekom FJ, Mooijaart SP, Maljaars PWJ | 2022-05-01 | Crohn’s Disease, Elderly, Frailty, Geriatric Assessment, Ulcerative Colitis | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association |
Dependency of R2 and R2 * relaxation on Gd-DTPA concentration in arterial blood: Influence of hematocrit and magnetic field strength. | van Dorth D, Venugopal K, Poot DHJ, Hirschler L, de Bresser J, Smits M, Hernandez-Tamames JA, Debacker CS, van Osch MJP | 2022-05-01 | arterial input function, dynamic susceptibility contrast MRI, hematocrit dependency, magnetic field strength, oxygen saturation, simulations | NMR in biomedicine |
Nurse-Physician Communication Around Identifying Palliative Care Needs in Nursing Home Residents. | van der Steen JT, Jongen EA, Lemos Dekker N, Bagchus L, Pasman HRW, Onwuteaka-Philipsen BD, Achterberg WP | 2022-05-01 | Journal of the American Medical Directors Association | |
Interprofessional Collaboration in Long-Term Care and Rehabilitation: A Systematic Review. | Doornebosch AJ, Smaling HJA, Achterberg WP | 2022-05-01 | Interprofessional collaboration, barriers, elderly, facilitators, geriatric, interdisciplinary, long-term care, rehabilitation | Journal of the American Medical Directors Association |
Activities for Residents of Dutch Nursing Homes during the COVID-19 Pandemic: A Qualitative Study. | Smeitink MMP, Smaling HJA, van Tol LS, Haaksma ML, Caljouw MAA, Achterberg WP | 2022-04-30 | COVID-19, SARS-Cov-2, dementia, geriatric care, long-term care, meaningful activities, nursing home, pandemic | International journal of environmental research and public health |
Types, Aspects, and Impact of Relocation Initiatives Deployed within and between Long-Term Care Facilities: A Scoping Review. | Broekharst DSE, Brouwers MPJ, Stoop A, Achterberg WP, Caljouw MAA | 2022-04-14 | long-term care, relocation, relocation initiative, scoping review, transfer, transition | International journal of environmental research and public health |
Job Demands, Work Functioning and Mental Health in Dutch Nursing Home Staff during the COVID-19 Outbreak: A Cross-Sectional Multilevel Study. | van Dijk Y, Janus SIM, de Boer MR, Achterberg WP, Roelen CAM, Zuidema SU | 2022-04-06 | COVID-19, burnout, depressive symptoms, job demands, nursing homes, work functioning | International journal of environmental research and public health |
DNA methylation in peripheral tissues and left-handedness. | Odintsova VV, Suderman M, Hagenbeek FA, Caramaschi D, Hottenga JJ, Pool R, Dolan CV, Ligthart L, van Beijsterveldt CEM, Willemsen G, de Geus EJC, Beck JJ, Ehli EA, Cuellar-Partida G, Evans DM, Medland SE, Relton CL, Boomsma DI, van Dongen J | 2022-04-04 | Scientific reports | |
Great saves or near misses? Severe maternal outcome in Metro East, South Africa: A region-wide population-based case-control study. | Heitkamp A, Vollmer Murray L, van den Akker T, Gebhardt GS, Sandberg EM, van Roosmalen J, Ter Wee MM, de Vries JI, Theron G | 2022-04-01 | South Africa, case control, maternal morbidity, maternal mortality, maternal near miss, population-based, severe maternal outcome | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics |
WHO next-generation partograph: revolutionary steps towards individualised labour care? | Maaløe N, van Roosmalen J, Dmello B, Kwast B, van den Akker T, Housseine N, Kujabi M, Meguid T, Kidanto H | 2022-04-01 | BJOG : an international journal of obstetrics and gynaecology | |
Nationwide confidential enquiries into maternal deaths because of obstetric hemorrhage in the Netherlands between 2006 and 2019. | Ramler PI, Beenakkers ICM, Bloemenkamp KWM, Van der Bom JG, Braams-Lisman BAM, Cornette JMJ, Kallianidis AF, Kuppens SMI, Rietveld AL, Schaap TP, Schutte JM, Stekelenburg J, Zwart JJ, Van den Akker T | 2022-04-01 | confidential enquiry, improvable care, lessons learned, maternal mortality, obstetric hemorrhage, postpartum hemorrhage | Acta obstetricia et gynecologica Scandinavica |
Confidential enquiry into maternal deaths in the Netherlands, 2006-2018. | Kallianidis AF, Schutte JM, Schuringa LEM, Beenakkers ICM, Bloemenkamp KWM, Braams-Lisman BAM, Cornette J, Kuppens SM, Rietveld AL, Schaap T, Stekelenburg J, Zwart JJ, van den Akker T | 2022-04-01 | confidential enquiry, maternal health, maternal mortality, the Netherlands | Acta obstetricia et gynecologica Scandinavica |
“Too much, too late”: data on stillbirths to improve interpretation of caesarean section rates. | Zethof S, Christou A, Benova L, van Roosmalen J, van den Akker T | 2022-04-01 | Bulletin of the World Health Organization | |
Mortality risk for different presenting complaints amongst older patients assessed with the Manchester triage system. | Lucke JA, Mooijaart SP, Conroy S, Blomaard LC, De Groot B, Nickel CH | 2022-04-01 | Emergency department, Manchester triage system, Mortality, Non-specific complaints, Older patients, Triage | European geriatric medicine |
Providing care for older adults in the Emergency Department: expert clinical recommendations from the European Task Force on Geriatric Emergency Medicine. | Lucke JA, Mooijaart SP, Heeren P, Singler K, McNamara R, Gilbert T, Nickel CH, Castejon S, Mitchell A, Mezera V, Van der Linden L, Lim SE, Thaur A, Karamercan MA, Blomaard LC, Dundar ZD, Chueng KY, Islam F, de Groot B, Conroy S | 2022-04-01 | Acute care, Emergency Medicine, Frailty, Geriatric Emergency Medicine, Geriatrics, Guidelines | European geriatric medicine |
Geriatric characteristics and the risk of drug-related hospital admissions in older Emergency Department patients. | Luttikhuis HM, Blomaard LC, van der Kaaij MAE, Gombert-Handoko KB, de Groot B, Mooijaart SP | 2022-04-01 | Adverse drug events, Emergency Department, Frailty, Hospitalization, Older adults | European geriatric medicine |
Geriatric assessment and treatment outcomes in a Dutch cohort of older patients with potentially curable esophageal cancer. | van Holstein Y, Trompet S, van Deudekom FJ, van Munster B, de Glas NA, van den Bos F, Uit den Boogaard A, van der Elst MJT, van der Kaaij MAE, Neelis KJ, Langers AMJ, Slingerland M, Portielje JEA, Mooijaart SP | 2022-04-01 | Esophageal cancer, chemoradiotherapy, geriatric assessment, geriatric oncology, mortality, treatment discontinuation | Acta oncologica (Stockholm, Sweden) |
Effect of Intramuscular vs Intra-articular Glucocorticoid Injection on Pain Among Adults With Knee Osteoarthritis: The KIS Randomized Clinical Trial. | Wang Q, Mol MF, Bos PK, Dorleijn DMJ, Vis M, Gussekloo J, Bindels PJE, Runhaar J, Bierma-Zeinstra SMA | 2022-04-01 | JAMA network open | |
Developing country-specific questions about end-of-life care for nursing home residents with advanced dementia using the nominal group technique with family caregivers. | Bavelaar L, Nicula M, Morris S, Kaasalainen S, Achterberg WP, Loucka M, Vlckova K, Thompson G, Cornally N, Hartigan I, Harding A, Preston N, Walshe C, Cousins E, Dening KH, De Vries K, Brazil K, van der Steen JT | 2022-04-01 | Dementia, End-of-life care, Family caregiver, Nursing home, Patient engagement, Shared decision making | Patient education and counseling |
Mandatory vaccination against COVID-19 for health and social care workers caring for older people. | Gordon AL, Achterberg WP, van Delden JJM | 2022-04-01 | COVID-19, ethics, frailty, older people, vaccination | Age and ageing |
Fat metabolism is associated with telomere length in six population-based studies. | van der Spek A, Karamujić-Čomić H, Pool R, Bot M, Beekman M, Garmaeva S, Arp PP, Henkelman S, Liu J, Alves AC, Willemsen G, van Grootheest G, Aubert G, Ikram MA, Jarvelin MR, Lansdorp P, Uitterlinden AG, Zhernakova A, Slagboom PE, Penninx BWJH, Boomsma DI, Amin N, van Duijn CM | 2022-03-31 | Human molecular genetics | |
Evaluation of the Value of Waist Circumference and Metabolomics in the Estimation of Visceral Adipose Tissue. | Boone SC, van Smeden M, Rosendaal FR, le Cessie S, Groenwold RHH, Jukema JW, van Dijk KW, Lamb HJ, Greenland P, Neeland IJ, Allison MA, Criqui MH, Budoff MJ, Lind LL, Kullberg J, Ahlström H, Mook-Kanamori DO, de Mutsert R | 2022-03-24 | added value, development, external validation, metabolomics, prediction, visceral adipose tissue | American journal of epidemiology |
Feasibility of establishing a Canadian Obstetric Survey System (CanOSS) for severe maternal morbidity: a study protocol. | D'Souza R, Seymour RJ, Knight M, Dzakpasu S, Joseph KS, Thorne S, Ospina MB, Barrett J, Cook J, Fell DB, Scott H, Metcalfe A, van den Akker T, Lapinsky S, Skeith L, Murray-Davis B, Shah P, Forte M, Ashraf R, Chundamala J, Hutchinson SA, Chen KK, Malhamé I | 2022-03-23 | adult intensive & critical care, audit, maternal medicine, obstetrics | BMJ open |
Timing of objectively-collected physical activity in relation to body weight and metabolic health in sedentary older people: a cross-sectional and prospective analysis. | Albalak G, Stijntjes M, Wijsman CA, Slagboom PE, van der Ouderaa FJ, Mooijaart SP, van Heemst D, Noordam R | 2022-03-01 | International journal of obesity (2005) | |
Characteristics and outcomes of older patients hospitalised for COVID-19 in the first and second wave of the pandemic in The Netherlands: the COVID-OLD study. | Smits RAL, Trompet S, van der Linden CMJ, van der Bol JM, Jansen SWM, Polinder-Bos HA, Willems HC, Barten DG, Blomaard LC, de Boer MGJ, van Deudekom FJA, Ellerbroek JLJ, Festen J, van de Glind EMM, Kampschreur LM, Karimi O, Kroon B, van Lanen MGJA, Lucke JA, Maas HAAM, Mattace-Raso FUS, van Munster BC, Reijerse L, Robben SHM, Ruiter R, Schouten HJ, Spies PE, Wassenburg A, Wijngaarden MA, Mooijaart SP | 2022-03-01 | COVID-19, frailty, in-hospital mortality, second pandemic wave | Age and ageing |
Geriatric emergency medicine-a model for frailty friendly healthcare. | Mooijaart SP, Carpenter CR, Conroy SP | 2022-03-01 | emergency medicine, evidence-based medicine, frailty, older people | Age and ageing |
Maintaining meaningful activities for persons with dementia during transitions of care: A systematic review. | Groenendaal M, Smaling HJA, Achterberg WP, Caljouw MAA | 2022-03-01 | Dementia, Meaningful activities, Person-centered care, Systematic review, Transitions of care | Geriatric nursing (New York, N.Y.) |
‘Don’t let the trial kill the intervention’: how can researchers and care home teams implement complex intervention trials in care homes? | Shenkin SD, Gordon AL, Johnston L, Henderson C, Achterberg WP | 2022-03-01 | Care homes, older people, systematic review, trials | Age and ageing |
Characteristics and outcomes of older patients hospitalised for COVID-19 in the first and second wave of the pandemic in The Netherlands: the COVID-OLD study | Smits RAL, Trompet S, van der Linden CMJ, van der Bol JM, Jansen SWM, Polinder-Bos HA, Willems HC, Barten DG, Blomaard LC, de Boer MGJ, van Deudekom FJA, Ellerbroek JLJ, Festen J, van de Glind EMM, Kampschreur LM, Karimi O, Kroon B, van Lanen MGJA, Lucke JA, Maas HAAM, Mattace-Raso FUS, van Munster BC, Reijerse L, Robben SHM, Ruiter R, Schouten HJ, Spies PE, Wassenburg A, Wijngaarden MA, Mooijaart SP | 2022-03-01 | Age and Ageing | |
Circulating angiopoietin-2 and angiogenic microRNAs associate with cerebral small vessel disease and cognitive decline in older patients reaching end-stage renal disease. | Bijkerk R, Kallenberg MH, Zijlstra LE, van den Berg BM, de Bresser J, Hammer S, Bron EE, Achterberg H, van Buchem MA, Berkhout-Byrne NC, Bos WJW, van Heemst D, Rabelink TJ, van Zonneveld AJ, van Buren M, Mooijaart S | 2022-02-25 | ageing, angiopoietin-2, cerebral small vessel disease, cognitive dysfunction, microRNAs | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association |
Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS. | Hop PJ, Zwamborn RAJ, Hannon E, Shireby GL, Nabais MF, Walker EM, van Rheenen W, van Vugt JJFA, Dekker AM, Westeneng HJ, Tazelaar GHP, van Eijk KR, Moisse M, Baird D, Al Khleifat A, Iacoangeli A, Ticozzi N, Ratti A, Cooper-Knock J, Morrison KE, Shaw PJ, Basak AN, Chiò A, Calvo A, Moglia C, Canosa A, Brunetti M, Grassano M, Gotkine M, Lerner Y, Zabari M, Vourc'h P, Corcia P, Couratier P, Mora Pardina JS, Salas T, Dion P, Ross JP, Henderson RD, Mathers S, McCombe PA, Needham M, Nicholson G, Rowe DB, Pamphlett R, Mather KA, Sachdev PS, Furlong S, Garton FC, Henders AK, Lin T, Ngo ST, Steyn FJ, Wallace L, Williams KL, Neto MM, Cauchi RJ, Blair IP, Kiernan MC, Drory V, Povedano M, de Carvalho M, Pinto S, Weber M, Rouleau GA, Silani V, Landers JE, Shaw CE, Andersen PM, McRae AF, van Es MA, Pasterkamp RJ, Wray NR, McLaughlin RL, Hardiman O, Kenna KP, Tsai E, Runz H, Al-Chalabi A, van den Berg LH, Van Damme P, Mill J, Veldink JH | 2022-02-23 | Science translational medicine | |
Severe COVID-19 in pregnancy is almost exclusively limited to unvaccinated women – time for policies to change. | Engjom H, van den Akker T, Aabakke A, Ayras O, Bloemenkamp K, Donati S, Cereda D, Overtoom E, Knight M | 2022-02-01 | The Lancet regional health. Europe | |
Commentary on the EMA reflection paper on the pharmaceutical development of medicines for use in the older population. | van Riet-Nales DA, van den Bemt B, van Bodegom D, Cerreta F, Dooley B, Eggenschwyler D, Hirschlérova B, Jansen PAF, Karapinar-Çarkit F, Moran A, Span J, Stegemann S, Sundberg K | 2022-02-01 | drug delivery, drug regulation, drug safety, health policy, public health | British journal of clinical pharmacology |
Management of post-acute COVID-19 patients in geriatric rehabilitation: EuGMS guidance. | van Haastregt JCM, Everink IHJ, Schols JMGA, Grund S, Gordon AL, Poot EP, Martin FC, O'Neill D, Petrovic M, Bachmann S, van Balen R, van Dam van Isselt L, Dockery F, Holstege MS, Landi F, Pérez LM, Roquer E, Smalbrugge M, Achterberg WP | 2022-02-01 | COVID-19, Geriatric rehabilitation, Guidance, Post-acute care, Quality assurance | European geriatric medicine |
Perceptions of peer contraceptive use and its influence on contraceptive method use and choice among young women and men in Kenya: a quantitative cross-sectional study. | Calhoun LM, Mirzoyants A, Thuku S, Benova L, Delvaux T, van den Akker T, McGuire C, Onyango B, Speizer IS | 2022-01-21 | Condom, Contraceptives, Family planning, Kenya, Peer, Social norms, Youth | Reproductive health |
Thyroid Function and Risk of Anemia: A Multivariable-Adjusted and Mendelian Randomization Analysis in the UK Biobank. | van Vliet NA, Kamphuis AEP, den Elzen WPJ, Blauw GJ, Gussekloo J, Noordam R, van Heemst D | 2022-01-18 | Mendelian randomization, UK Biobank, anemia, thyroid status | The Journal of clinical endocrinology and metabolism |
Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression. | Jonkman TH, Dekkers KF, Slieker RC, Grant CD, Ikram MA, van Greevenbroek MMJ, Franke L, Veldink JH, Boomsma DI, Slagboom PE, Consortium BIOS, Heijmans BT | 2022-01-14 | Genome biology | |
Positive health during the COVID-19 pandemic: a survey among community-dwelling older individuals in the Netherlands. | Moens IS, van Gerven LJ, Debeij SM, Bakker CH, Moester MJC, Mooijaart SP, van der Pas S, Vangeel M, Gussekloo J, Drewes YM, Elzen WPJD | 2022-01-13 | Bodily functions, COVID-19, Daily functioning, Meaningfulness, Mental well-being, Online questionnaire, Quality of life, Social participation | BMC geriatrics |
Circulating miRNAs and Vascular Injury Markers Associate with Cardiovascular Function in Older Patients Reaching End-Stage Kidney Disease. | Zhao Q, Nooren SJL, Zijlstra LE, Westenberg JJM, Kroft LJM, Jukema JW, Berkhout-Byrne NC, Rabelink TJ, van Zonneveld AJ, van Buren M, Mooijaart SP, Bijkerk R | 2022-01-10 | angiopoietin-2, cardiovascular disease (CVD), end-stage kidney disease (ESKD), miRNAs, pulse wave velocity (PWV) | Non-coding RNA |
Declining daily functioning as a prelude to a hip fracture in older persons-an individual patient data meta-analysis. | Ravensbergen WM, Blom JW, Kingston A, Robinson L, Kerse N, Teh RO, Groenwold RHH, Gussekloo J | 2022-01-06 | disability, function, hip fracture, older people | Age and ageing |
Making progress: but a way to go-the age and ageing care-home collection. | Gordon AL, Bennett C, Goodman C, Achterberg WP | 2022-01-06 | care homes, methodology, older people, research | Age and ageing |
Do we AGREE on the targets of antihypertensive drug treatment in older adults: a systematic review of guidelines on primary prevention of cardiovascular diseases. | Bogaerts JMK, von Ballmoos LM, Achterberg WP, Gussekloo J, Streit S, van der Ploeg MA, Drewes YM, Poortvliet RKE | 2022-01-06 | antihypertensive drug therapy, guidelines, older people, primary cardiovascular prevention, systematic review | Age and ageing |
The Impact of Social Distancing Due to the COVID-19 Pandemic on People with Dementia, Family Carers and Healthcare Professionals: A Qualitative Study. | Smaling HJA, Tilburgs B, Achterberg WP, Visser M | 2022-01-04 | COVID-19, dementia, family carers, home care, long-term care, social isolation | International journal of environmental research and public health |
1H-NMR metabolomics-based surrogates to impute common clinical risk factors and endpoints. | Bizzarri D, Reinders MJT, Beekman M, Slagboom PE, Bbmri-Nl, van den Akker EB | 2022-01-01 | (1)H-NMR metabolomics, Association studies, Epidemiology, Missing values, Regression models, Surrogate clinical variables | EBioMedicine |
Associations of metabolomic profiles with circulating vitamin E and urinary vitamin E metabolites in middle-aged individuals. | Luo J, Hashimoto Y, Martens LG, Meulmeester FL, Ashrafi N, Mook-Kanamori DO, Rosendaal FR, Jukema JW, van Dijk KW, Mills K, le Cessie S, Noordam R, van Heemst D | 2022-01-01 | Carboxymethyl-hydroxychroman, Lipid profile, Tocopheronolactone hydroquinone, Vitamin E | Nutrition (Burbank, Los Angeles County, Calif.) |
Effect of breathing on venous return during delayed cord clamping: an observational study. | Brouwer E, Knol R, Kroushev A, Van Den Akker T, Hooper SB, Roest AA, Te Pas AB | 2022-01-01 | cardiology, neonatology, physiology | Archives of disease in childhood. Fetal and neonatal edition |
SARS-CoV-2 infection in pregnancy during the first wave of COVID-19 in the Netherlands: a prospective nationwide population-based cohort study (NethOSS). | Overtoom EM, Rosman AN, Zwart JJ, Vogelvang TE, Schaap TP, van den Akker T, Bloemenkamp K | 2022-01-01 | coronavirus disease 2019, obstetric surveillance system, pregnancy, pregnancy complications, severe acute respiratory syndrome coronavirus 2 | BJOG : an international journal of obstetrics and gynaecology |
Clinical value of early assessment of hyperfibrinolysis by rotational thromboelastometry during postpartum hemorrhage for the prediction of severity of bleeding: A multicenter prospective cohort study in the Netherlands. | Tahitu M, Ramler PI, Gillissen A, Caram-Deelder C, Henriquez DDCA, de Maat MPM, Duvekot JJ, Eikenboom J, Bloemenkamp KWM, van den Akker T, van der Bom JG | 2022-01-01 | ROTEM®, hyperfibrinolysis, postpartum hemorrhage, rotational thromboelastometry, severity of bleeding | Acta obstetricia et gynecologica Scandinavica |
Evaluating Clinical Outcomes and Physiological Perspectives in Studies Investigating Respiratory Support for Babies Born at Term With or at Risk of Transient Tachypnea: A Narrative Review. | McGillick EV, Te Pas AB, van den Akker T, Keus JMH, Thio M, Hooper SB | 2022-01-01 | airway liquid, end-expiratory pressure, respiratory distress, respiratory support, transient tachypnea of the newborn | Frontiers in pediatrics |
“I Got What I Came for”: A Qualitative Exploration into Family Planning Client Satisfaction in Dosso Region, Niger. | Calhoun LM, Maytan-Joneydi A, Nouhou AM, Benova L, Delvaux T, van den Akker T, Agali BI, Speizer IS | 2022-01-01 | Niger, client satisfaction, contraception, family planning | Open access journal of contraception |
Contraceptive method use trajectories among young women in Kenya: A qualitative study. | Calhoun LM, Mandal M, Onyango B, Waga E, McGuire C, Zulu EM, van den Akker T, Benova L, Delvaux T, Speizer IS | 2022-01-01 | contraception, family planning, life course, method choice, youth | Frontiers in global women's health |
“Separated during the first hours”-Postnatal care for women and newborns during the COVID-19 pandemic: A mixed-methods cross-sectional study from a global online survey of maternal and newborn healthcare providers. | Semaan A, Dey T, Kikula A, Asefa A, Delvaux T, Langlois EV, van den Akker T, Benova L | 2022-01-01 | PLOS global public health | |
No increase in use of hospitals for childbirth in Tanzania over 25 years: Accumulation of inequity among poor, rural, high parity women. | Straneo M, Beňová L, van den Akker T, Pembe AB, Smekens T, Hanson C | 2022-01-01 | PLOS global public health | |
HPV type-specific distribution among family members and linen in households of cutaneous wart patients. | Ghorzang E, de Koning MNC, Bouwes Bavinck JN, Gussekloo J, Quint KD, Goeman JJ, Feltkamp MCW, Bruggink SC, Eekhof JAH | 2022-01-01 | Journal of the European Academy of Dermatology and Venereology : JEADV | |
Association of cognitive function with increased risk of cancer death and all-cause mortality: Longitudinal analysis, systematic review, and meta-analysis of prospective observational studies. | Rostamian S, le Cessie S, Marijt KA, Jukema JW, Mooijaart SP, van Buchem MA, van Hall T, Gussekloo J, Trompet S | 2022-01-01 | PloS one | |
Incorporating Baseline Outcome Data in Individual Participant Data Meta-Analysis of Non-randomized Studies. | Syrogiannouli L, Wildisen L, Meuwese C, Bauer DC, Cappola AR, Gussekloo J, den Elzen WPJ, Trompet S, Westendorp RGJ, Jukema JW, Ferrucci L, Ceresini G, Åsvold BO, Chaker L, Peeters RP, Imaizumi M, Ohishi W, Vaes B, Völzke H, Sgarbi JA, Walsh JP, Dullaart RPF, Bakker SJL, Iacoviello M, Rodondi N, Del Giovane C | 2022-01-01 | baseline imbalance, cohorts, continuous outcome, individual participant data, non-randomized studies | Frontiers in psychiatry |
MRI-Based Classification of Neuropsychiatric Systemic Lupus Erythematosus Patients With Self-Supervised Contrastive Learning. | Inglese F, Kim M, Steup-Beekman GM, Huizinga TWJ, van Buchem MA, de Bresser J, Kim DS, Ronen I | 2022-01-01 | Systemic Lupus Erythematosus, cohort studies, magnetic resonance imaging, neuroimaging, unsupervised machine learning | Frontiers in neuroscience |
Different cardiovascular risk factors are related to distinct white matter hyperintensity MRI phenotypes in older adults. | Keller JA, Kant IMJ, Slooter AJC, van Montfort SJT, van Buchem MA, van Osch MJP, Hendrikse J, de Bresser J | 2022-01-01 | Cardiovascular risk factors, Cerebral small vessel disease, Cognitive decline, Magnetic resonance imaging, White matter hyperintensities | NeuroImage. Clinical |
COVID-19 Pandemic and Consecutive Changes in Geriatric Rehabilitation Structures and Processes – A Deeper Attempt to Explain the COVID Rehabilitation Paradox (Lessons to Learn to Ensure High Quality of Care in GR Services). | Grund S, Gordon AL, Bauer JM, Achterberg WP, Schols JMGA | 2022-01-01 | The journal of nutrition, health & aging | |
Occurrence and Timing of Advance Care Planning in Persons With Dementia in General Practice: Analysis of Linked Electronic Health Records and Administrative Data. | Azizi B, Tilburgs B, van Hout HPJ, van der Heide I, Verheij RA, Achterberg WP, van der Steen JT, Joling KJ | 2022-01-01 | advance care planning, data linkage, dementia, general practice, primary care | Frontiers in public health |
Cost-effectiveness of dementia training for caregivers in caregiver-patient dyads: A randomized controlled study. | Birkenhäger-Gillesse EG, Achterberg WP, Janus SIM, Zuidema SU, van den Hout WB | 2022-01-01 | caregivers, cost‐effectiveness, dementia, health resource, psychosocial intervention, training | Alzheimer's & dementia (New York, N. Y.) |
Classical risk factors for primary coronary artery disease from an aging perspective through Mendelian Randomization | Jansen SA, Huiskens B, Trompet S, Jukema J, Mooijaart SP, Willems van Dijk K, van Heemst D, Noordam R | 2021-12-21 | GeroScience | |
Diet-Derived Antioxidants Do Not Decrease Risk of Ischemic Stroke: A Mendelian Randomization Study in 1 Million People. | Martens LG, Luo J, Willems van Dijk K, Jukema JW, Noordam R, van Heemst D | 2021-12-07 | antioxidants, cardiovascular disease, diet, ischemic stroke, oxidative stress | Journal of the American Heart Association |
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour. | Mills MC, Tropf FC, Brazel DM, van Zuydam N, Vaez A, Pers TH, Snieder H, Perry JRB, Ong KK, den Hoed M, Barban N, Day FR | 2021-12-01 | Nature human behaviour | |
Functional Performance After Complex Endovascular Aortic Repair: A Single-Center Retrospective Cohort Study. | Warmerdam BWCM, van Holstein Y, Eefting D, van Rijswijk CSP, van der Meer RW, Mooijaart SP, Hamming JF, van der Vorst JR, van Schaik J | 2021-12-01 | activities of daily living, complex aortic aneurysm repair, endovascular treatment/therapy, frailty, functional performance | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists |
Trends in quality of care and dying perceived by family caregivers of nursing home residents with dementia 2005-2019. | Klapwijk MS, Bolt SR, Boogaard JA, Ten Koppel M, Gijsberts MH, van Leussen C, The BA, Meijers JM, Schols JM, Pasman HRW, Onwuteaka-Philipsen BD, Deliens L, Van den Block L, Mertens B, de Vet HC, Caljouw MA, Achterberg WP, van der Steen JT | 2021-12-01 | Dementia, end-of-life care, geriatrics, nursing homes, palliative care, quality of health care | Palliative medicine |
COVID-19 management in nursing homes by outbreak teams (MINUTES) – study description and data characteristics: a qualitative study. | van Tol LS, Smaling HJA, Groothuijse JM, Doornebosch AJ, Janus SIM, Zuidema SU, Caljouw MAA, Achterberg WP, de Waal MWM | 2021-11-30 | COVID-19, health policy, infection control, public health, qualitative research | BMJ open |
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. | Boer CG, Hatzikotoulas K, Southam L, Stefánsdóttir L, Zhang Y, Coutinho de Almeida R, Wu TT, Zheng J, Hartley A, Teder-Laving M, Skogholt AH, Terao C, Zengini E, Alexiadis G, Barysenka A, Bjornsdottir G, Gabrielsen ME, Gilly A, Ingvarsson T, Johnsen MB, Jonsson H, Kloppenburg M, Luetge A, Lund SH, Mägi R, Mangino M, Nelissen RRGHH, Shivakumar M, Steinberg J, Takuwa H, Thomas LF, Tuerlings M, Babis GC, Cheung JPY, Kang JH, Kraft P, Lietman SA, Samartzis D, Slagboom PE, Stefansson K, Thorsteinsdottir U, Tobias JH, Uitterlinden AG, Winsvold B, Zwart JA, Smith GD, Sham PC, Thorleifsson G, Gaunt TR, Morris AP, Valdes AM, Tsezou A, Cheah KSE, Ikegawa S, Hveem K, Esko T, Wilkinson JM, Meulenbelt I, Michael Lee MT, van Meurs JBJ, Styrkársdóttir U, Zeggini E | 2021-11-24 | Cell | |
Impact of the COVID-19 pandemic on symptoms of anxiety and depression and health-related quality of life in older patients with chronic kidney disease. | Voorend CGN, van Oevelen M, Nieberg M, Meuleman Y, Franssen CFM, Joosten H, Berkhout-Byrne NC, Abrahams AC, Mooijaart SP, Bos WJW, van Buren M | 2021-11-19 | Aged, Chronic kidney diseases, Coronavirus disease-2019 (COVID-19) pandemic, Mental health, Quality of life | BMC geriatrics |
Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling. | van Vliet NA, Bos MM, Thesing CS, Chaker L, Pietzner M, Houtman E, Neville MJ, Li-Gao R, Trompet S, Mustafa R, Ahmadizar F, Beekman M, Bot M, Budde K, Christodoulides C, Dehghan A, Delles C, Elliott P, Evangelou M, Gao H, Ghanbari M, van Herwaarden AE, Ikram MA, Jaeger M, Jukema JW, Karaman I, Karpe F, Kloppenburg M, Meessen JMTA, Meulenbelt I, Milaneschi Y, Mooijaart SP, Mook-Kanamori DO, Netea MG, Netea-Maier RT, Peeters RP, Penninx BWJH, Sattar N, Slagboom PE, Suchiman HED, Völzke H, Willems van Dijk K, Noordam R, van Heemst D | 2021-11-03 | Coronary artery disease, Mendelian randomization, Metabolomics, Thyroid hormones | BMC medicine |
Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure. | Wang H, Noordam R, Cade BE, Schwander K, Winkler TW, Lee J, Sung YJ, Bentley AR, Manning AK, Aschard H, Kilpeläinen TO, Ilkov M, Brown MR, Horimoto AR, Richard M, Bartz TM, Vojinovic D, Lim E, Nierenberg JL, Liu Y, Chitrala K, Rankinen T, Musani SK, Franceschini N, Rauramaa R, Alver M, Zee PC, Harris SE, van der Most PJ, Nolte IM, Munroe PB, Palmer ND, Kühnel B, Weiss S, Wen W, Hall KA, Lyytikäinen LP, O'Connell J, Eiriksdottir G, Launer LJ, de Vries PS, Arking DE, Chen H, Boerwinkle E, Krieger JE, Schreiner PJ, Sidney S, Shikany JM, Rice K, Chen YI, Gharib SA, Bis JC, Luik AI, Ikram MA, Uitterlinden AG, Amin N, Xu H, Levy D, He J, Lohman KK, Zonderman AB, Rice TK, Sims M, Wilson G, Sofer T, Rich SS, Palmas W, Yao J, Guo X, Rotter JI, Biermasz NR, Mook-Kanamori DO, Martin LW, Barac A, Wallace RB, Gottlieb DJ, Komulainen P, Heikkinen S, Mägi R, Milani L, Metspalu A, Starr JM, Milaneschi Y, Waken RJ, Gao C, Waldenberger M, Peters A, Strauch K, Meitinger T, Roenneberg T, Völker U, Dörr M, Shu XO, Mukherjee S, Hillman DR, Kähönen M, Wagenknecht LE, Gieger C, Grabe HJ, Zheng W, Palmer LJ, Lehtimäki T, Gudnason V, Morrison AC, Pereira AC, Fornage M, Psaty BM, van Duijn CM, Liu CT, Kelly TN, Evans MK, Bouchard C, Fox ER, Kooperberg C, Zhu X, Lakka TA, Esko T, North KE, Deary IJ, Snieder H, Penninx BWJH, Gauderman WJ, Rao DC, Redline S, van Heemst D | 2021-11-01 | Molecular psychiatry | |
The burden of severe hypertensive disorders of pregnancy on perinatal outcomes: a nationwide case-control study in Suriname. | Prüst ZD, Kodan LR, van den Akker T, Bloemenkamp KWM, Rijken MJ, Verschueren KJC | 2021-11-01 | Caribbean, Latin America, South America, Suriname, adverse perinatal outcome, eclampsia, hypertensive disorders of pregnancy, perinatal mortality, preeclampsia | AJOG global reports |
Association Between Blood Pressure Variability With Dementia and Cognitive Impairment: A Systematic Review and Meta-Analysis. | de Heus RAA, Tzourio C, Lee EJL, Opozda M, Vincent AD, Anstey KJ, Hofman A, Kario K, Lattanzi S, Launer LJ, Ma Y, Mahajan R, Mooijaart SP, Nagai M, Peters R, Turnbull D, Yano Y, Claassen JAHR, Tully PJ | 2021-11-01 | Alzheimer disease, blood pressure, cerebrovascular disorders, dementia, hemodynamics, meta-analysis, stroke | Hypertension (Dallas, Tex. : 1979) |
Development and validation of the PORTRET tool to predict recurrence, overall survival, and other-cause mortality in older patients with breast cancer in the Netherlands: a population-based study. | van der Plas-Krijgsman WG, Giardiello D, Putter H, Steyerberg EW, Bastiaannet E, Stiggelbout AM, Mooijaart SP, Kroep JR, Portielje JEA, Liefers GJ, de Glas NA | 2021-11-01 | The lancet. Healthy longevity | |
Goal attainment scaling with older people in general practice: A feasibility study. | van Blijswijk SC, Gussekloo J, Heijmans FM, Wind AW, den Elzen WP, Blom JW | 2021-11-01 | Care-action-plan, Community-dwelling older people, Evaluation method, General practice, Goal attainment scaling, Goal setting, Individualised care, Personalised care, Practice nurses, Primary care | International journal of nursing studies advances |
Telephone follow-up to reduce unplanned hospital returns for older emergency department patients: A randomized trial. | van Loon-van Gaalen M, van der Linden MC, Gussekloo J, van der Mast RC | 2021-11-01 | emergency department, geriatric, older patients, post-discharge follow-up, telephone | Journal of the American Geriatrics Society |
Association of Thyroid Dysfunction With Cognitive Function: An Individual Participant Data Analysis. | van Vliet NA, van Heemst D, Almeida OP, Åsvold BO, Aubert CE, Bae JB, Barnes LE, Bauer DC, Blauw GJ, Brayne C, Cappola AR, Ceresini G, Comijs HC, Dartigues JF, Degryse JM, Dullaart RPF, van Eersel MEA, den Elzen WPJ, Ferrucci L, Fink HA, Flicker L, Grabe HJ, Han JW, Helmer C, Huisman M, Ikram MA, Imaizumi M, de Jongh RT, Jukema JW, Kim KW, Kuller LH, Lopez OL, Mooijaart SP, Moon JH, Moutzouri E, Nauck M, Parle J, Peeters RP, Samuels MH, Schmidt CO, Schminke U, Slagboom PE, Stordal E, Vaes B, Völzke H, Westendorp RGJ, Yamada M, Yeap BB, Rodondi N, Gussekloo J, Trompet S | 2021-11-01 | JAMA internal medicine | |
Different phenotypes of neuropsychiatric systemic lupus erythematosus are related to a distinct pattern of structural changes on brain MRI. | Inglese F, Kant IMJ, Monahan RC, Steup-Beekman GM, Huizinga TWJ, van Buchem MA, Magro-Checa C, Ronen I, de Bresser J | 2021-11-01 | Brain, Lupus erythematosus, Systemic, Magnetic resonance imaging, Phenotype | European radiology |
Cortical cerebral microinfarcts on 7T MRI: Risk factors, neuroimaging correlates and cognitive functioning – The Medea-7T study. | Zwartbol MH, Rissanen I, Ghaznawi R, de Bresser J, Kuijf HJ, Blom K, Witkamp TD, Koek HL, Biessels GJ, Hendrikse J, Geerlings MI | 2021-11-01 | Microinfarcts, cerebrovascular disease, cognitive functioning, dementia, cardiovascular risk factors | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism |
Validating biomarkers and models for epigenetic inference of alcohol consumption from blood. | Maas SCE, Vidaki A, Teumer A, Costeira R, Wilson R, van Dongen J, Beekman M, Völker U, Grabe HJ, Kunze S, Ladwig KH, van Meurs JBJ, Uitterlinden AG, Voortman T, Boomsma DI, Slagboom PE, van Heemst D, van der Kallen CJH, van den Berg LH, Waldenberger M, Völzke H, Peters A, Bell JT, Ikram MA, Ghanbari M, Kayser M | 2021-10-26 | Alcohol inference, Blood, DNA methylation, Epigenetics, Inference, Prediction | Clinical epigenetics |
The Relation Between Adult Weight Gain, Adipocyte Volume, and the Metabolic Profile at Middle Age. | Verkouter I, Noordam R, Loh NY, van Dijk KW, Zock PL, Mook-Kanamori DO, le Cessie S, Rosendaal FR, Karpe F, Christodoulides C, de Mutsert R | 2021-10-21 | adipocyte volume, body mass index, cohort study, metabolic profile, metabolomics, weight gain | The Journal of clinical endocrinology and metabolism |
Inequity in uptake of hospital-based childbirth care in rural Tanzania: analysis of the 2015-16 Tanzania Demographic and Health Survey. | Straneo M, Benova L, Hanson C, Fogliati P, Pembe AB, Smekens T, van den Akker T | 2021-10-12 | Obstetrics, equity, health care utilization, health facilities, health inequalities, hospital, maternal and child health, maternal services, poverty, primary health care, rural | Health policy and planning |
Maternal mortality: near-miss events in middle-income countries, a systematic review. | Heitkamp A, Meulenbroek A, van Roosmalen J, Gebhardt S, Vollmer L, de Vries JI, Theron G, van den Akker T | 2021-10-01 | Bulletin of the World Health Organization | |
Design of a consensus-based geriatric assessment tailored for older chronic kidney disease patients: results of a pragmatic approach. | Voorend CGN, Joosten H, Berkhout-Byrne NC, Diepenbroek A, Franssen CFM, Bos WJW, Van Buren M, Mooijaart SP | 2021-10-01 | Aged, Chronic kidney diseases, Clinical decision-making, Consensus development, Frailty, Geriatric assessment | European geriatric medicine |
Identical twins carry a persistent epigenetic signature of early genome programming. | van Dongen J, Gordon SD, McRae AF, Odintsova VV, Mbarek H, Breeze CE, Sugden K, Lundgren S, Castillo-Fernandez JE, Hannon E, Moffitt TE, Hagenbeek FA, van Beijsterveldt CEM, Jan Hottenga J, Tsai PC, Min JL, Hemani G, Ehli EA, Paul F, Stern CD, Heijmans BT, Slagboom PE, Daxinger L, van der Maarel SM, de Geus EJC, Willemsen G, Montgomery GW, Reversade B, Ollikainen M, Kaprio J, Spector TD, Bell JT, Mill J, Caspi A, Martin NG, Boomsma DI | 2021-09-28 | Nature communications | |
Men’s comfort in distributing or receiving HIV self-test kits from close male social network members in Dar Es Salaam, Tanzania: baseline results from the STEP project. | Matovu JKB, Mbita G, Hamilton A, Mhando F, Sims WM, Thompson N, Komba AN, Lija J, Zhang J, van den Akker T, Duncan DT, Choko AT, Conserve DF | 2021-09-24 | HIV, HIV self-testing, Men, Social networks, Tanzania | BMC public health |
Functional Changes of T-Cell Subsets with Age and CMV Infection. | Hassouneh F, Goldeck D, Pera A, van Heemst D, Slagboom PE, Pawelec G, Solana R | 2021-09-15 | CD57, T-cell response, aging, cytomegalovirus | International journal of molecular sciences |
Familial longevity is associated with lower baseline bone turnover but not differences in bone turnover in response to rhTSH. | Zutinic A, Roelfsema F, Pijl H, Ballieux BE, Westendorp RGJ, Blauw GJ, van Heemst D | 2021-09-07 | bone metabolism, longevity, rhTSH, thyroid | Aging |
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. | Boer CG, Hatzikotoulas K, Southam L, Stefánsdóttir L, Zhang Y, Coutinho de Almeida R, Wu TT, Zheng J, Hartley A, Teder-Laving M, Skogholt AH, Terao C, Zengini E, Alexiadis G, Barysenka A, Bjornsdottir G, Gabrielsen ME, Gilly A, Ingvarsson T, Johnsen MB, Jonsson H, Kloppenburg M, Luetge A, Lund SH, Mägi R, Mangino M, Nelissen RRGHH, Shivakumar M, Steinberg J, Takuwa H, Thomas LF, Tuerlings M, Babis GC, Cheung JPY, Kang JH, Kraft P, Lietman SA, Samartzis D, Slagboom PE, Stefansson K, Thorsteinsdottir U, Tobias JH, Uitterlinden AG, Winsvold B, Zwart JA, Davey Smith G, Sham PC, Thorleifsson G, Gaunt TR, Morris AP, Valdes AM, Tsezou A, Cheah KSE, Ikegawa S, Hveem K, Esko T, Wilkinson JM, Meulenbelt I, Lee MTM, van Meurs JBJ, Styrkársdóttir U, Zeggini E | 2021-09-02 | drug targets, effector genes, functional genomics, genetic architecture, genome-wide association meta-analysis, osteoarthritis | Cell |
Relationships Between 24-hour LH and Testosterone Concentrations and With Other Pituitary Hormones in Healthy Older Men. | van der Spoel E, Roelfsema F, van Heemst D | 2021-09-01 | ageing, cross-correlation, luteinizing hormone, men, pituitary hormones, testosterone | Journal of the Endocrine Society |
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation. | Min JL, Hemani G, Hannon E, Dekkers KF, Castillo-Fernandez J, Luijk R, Carnero-Montoro E, Lawson DJ, Burrows K, Suderman M, Bretherick AD, Richardson TG, Klughammer J, Iotchkova V, Sharp G, Al Khleifat A, Shatunov A, Iacoangeli A, McArdle WL, Ho KM, Kumar A, Söderhäll C, Soriano-Tárraga C, Giralt-Steinhauer E, Kazmi N, Mason D, McRae AF, Corcoran DL, Sugden K, Kasela S, Cardona A, Day FR, Cugliari G, Viberti C, Guarrera S, Lerro M, Gupta R, Bollepalli S, Mandaviya P, Zeng Y, Clarke TK, Walker RM, Schmoll V, Czamara D, Ruiz-Arenas C, Rezwan FI, Marioni RE, Lin T, Awaloff Y, Germain M, Aïssi D, Zwamborn R, van Eijk K, Dekker A, van Dongen J, Hottenga JJ, Willemsen G, Xu CJ, Barturen G, Català-Moll F, Kerick M, Wang C, Melton P, Elliott HR, Shin J, Bernard M, Yet I, Smart M, Gorrie-Stone T, Shaw C, Al Chalabi A, Ring SM, Pershagen G, Melén E, Jiménez-Conde J, Roquer J, Lawlor DA, Wright J, Martin NG, Montgomery GW, Moffitt TE, Poulton R, Esko T, Milani L, Metspalu A, Perry JRB, Ong KK, Wareham NJ, Matullo G, Sacerdote C, Panico S, Caspi A, Arseneault L, Gagnon F, Ollikainen M, Kaprio J, Felix JF, Rivadeneira F, Tiemeier H, van IJzendoorn MH, Uitterlinden AG, Jaddoe VWV, Haley C, McIntosh AM, Evans KL, Murray A, Räikkönen K, Lahti J, Nohr EA, Sørensen TIA, Hansen T, Morgen CS, Binder EB, Lucae S, Gonzalez JR, Bustamante M, Sunyer J, Holloway JW, Karmaus W, Zhang H, Deary IJ, Wray NR, Starr JM, Beekman M, van Heemst D, Slagboom PE, Morange PE, Trégouët DA, Veldink JH, Davies GE, de Geus EJC, Boomsma DI, Vonk JM, Brunekreef B, Koppelman GH, Alarcón-Riquelme ME, Huang RC, Pennell CE, van Meurs J, Ikram MA, Hughes AD, Tillin T, Chaturvedi N, Pausova Z, Paus T, Spector TD, Kumari M, Schalkwyk LC, Visscher PM, Davey Smith G, Bock C, Gaunt TR, Bell JT, Heijmans BT, Mill J, Relton CL | 2021-09-01 | Nature genetics | |
Clinical value of early viscoelastometric point-of-care testing during postpartum hemorrhage for the prediction of severity of bleeding: A multicenter prospective cohort study in the Netherlands. | Ramler PI, Gillissen A, Henriquez DDCA, Caram-Deelder C, Markovski AA, de Maat MPM, Duvekot JJ, Eikenboom JCJ, Bloemenkamp KWM, van Lith JMM, van den Akker T, van der Bom JG | 2021-09-01 | FIBTEM A5, blood transfusion, fibrinogen, maternal mortality, point-of-care testing, postpartum hemorrhage, rotational thromboelastometry, severe acute maternal morbidity | Acta obstetricia et gynecologica Scandinavica |
Availability of facility resources and services and infection-related maternal outcomes in the WHO Global Maternal Sepsis Study: a cross-sectional study. | Brizuela V, Cuesta C, Bartolelli G, Abdosh AA, Abou Malham S, Assarag B, Castro Banegas R, Díaz V, El-Kak F, El Sheikh M, Pérez AM, Souza JP, Bonet M, Abalos E | 2021-09-01 | The Lancet. Global health | |
Emergency department management of older people living with frailty: a guide for emergency practitioners. | Hogervorst VM, Buurman BM, De Jonghe A, van Oppen JD, Nickel CH, Lucke J, Blomaard LC, Thaur A, Mooijaart SP, Banerjee J, Wallace J, de Groot B, Conroy SP | 2021-09-01 | acute care, assessment, emergency department, geriatrics | Emergency medicine journal : EMJ |
Determining preoperative brain MRI features and occurrence of postoperative delirium. | Kant IMJ, de Bresser J, Slooter AJC | 2021-09-01 | Journal of psychosomatic research | |
Family involvement in the Namaste care family program for dementia: A qualitative study on experiences of family, nursing home staff, and volunteers. | Tasseron-Dries PEM, Smaling HJA, Doncker SMMM, Achterberg WP, van der Steen JT | 2021-09-01 | Dementia, Experiences, Family caregivers, Family involvement, Nursing home, Qualitative research, Quality of life | International journal of nursing studies |
Can the Robson 10 Group Classification System help identify which groups of women are driving the high caesarean section rate in major private hospitals in eastern Ethiopia? A cross-sectional study. | Geze S, Tura AK, Fage SG, van den Akker T | 2021-08-26 | audit, epidemiology, obstetrics, public health | BMJ open |
eHealth in Geriatric Rehabilitation: Systematic Review of Effectiveness, Feasibility, and Usability. | Kraaijkamp JJM, van Dam van Isselt EF, Persoon A, Versluis A, Chavannes NH, Achterberg WP | 2021-08-19 | digital health, eHealth, effectiveness, feasibility, geriatric rehabilitation, mHealth, systematic review, usability | Journal of medical Internet research |
Trends in population health and demography. | Maaløe N, Housseine N, Meguid T, Tellier S, van Roosmalen J, Meyrowitsch DW, van den Akker T | 2021-08-14 | Lancet (London, England) | |
The effects of single and a combination of determinants of anaemia in the very old: results from the TULIPS consortium. | Wang PC, Gussekloo J, Arai Y, Abe Y, Blom JW, Duncan R, Jagger C, Kerse N, Martin-Ruiz C, Palapar L, den Elzen WPJ | 2021-08-09 | Inflammation, Iron deficiency, Low haemoglobin levels, Renal impairment, Vitamin B12/folate deficiency | BMC geriatrics |
Evaluating the effect of interventions for strengthening non-physician anesthetists’ education in Ethiopia: a pre- and post-evaluation study. | Asemu YM, Yigzaw T, Desta FA, Scheele F, van den Akker T | 2021-08-08 | Anesthesia, Competence, Education quality, Ethiopia, Non-physician anesthetists, Objective structured clinical examination | BMC medical education |
Stratification of Type 2 Diabetes by Age of Diagnosis in the UK Biobank Reveals Subgroup-Specific Genetic Associations and Causal Risk Profiles. | Noordam R, Läll K, Smit RAJ, Laisk T, Metspalu A, Esko T, Milani L, Loos RJF, Mägi R, Willems van Dijk K, van Heemst D | 2021-08-01 | Diabetes | |
Publisher Correction: Identification of 371 genetic variants for age at first sex and birth linked to externalising behavior. | Mills MC, Tropf FC, Brazel DM, van Zuydam N, Vaez A, Pers TH, Snieder H, Perry JRB, Ong KK, den Hoed M, Barban N, Day FR | 2021-08-01 | Nature human behaviour | |
A narrative review of frailty assessment in older patients at the emergency department. | van Dam CS, Hoogendijk EO, Mooijaart SP, Smulders YM, de Vet RCW, Lucke JA, Blomaard LC, Otten RHJ, Muller M, Nanayakkara PWB, Trappenburg MC, Peters MJL | 2021-08-01 | European journal of emergency medicine : official journal of the European Society for Emergency Medicine | |
Managing Pain and Psychosis Symptoms in Nursing Home Patients: Results from a Cluster-Randomized Controlled Trial (COSMOS). | Habiger TF, Achterberg WP, Flo-Groeneboom E, Mannseth J, Husebo BS | 2021-08-01 | Pain, dementia, nursing home, opioid analgesics, psychosis symptoms | Journal of the American Medical Directors Association |
Measuring positive caregiving experiences in family caregivers of nursing home residents: A comparison of the Positive Experiences Scale, Gain in Alzheimer Care INstrument, and Positive Aspects of Caregiving questionnaire. | Smaling HJ, Joling KJ, Achterberg WP, Francke AL, van der Steen JT | 2021-08-01 | caregivers, dementia, internal consistency, nursing homes, positive caregiving experiences | Geriatrics & gerontology international |
The prevalence of pain in Huntington’s disease in a large worldwide cohort. | Sprenger GP, Roos RAC, van Zwet E, Reijntjes RH, Achterberg WP, de Bot ST | 2021-08-01 | Analgesics, Huntington's disease, Pain, Pain interference, Painful conditions | Parkinsonism & related disorders |
Health facility capacity to provide postabortion care in Afghanistan: a cross-sectional study. | Maruf F, Tappis H, Lu E, Yaqubi GS, Stekelenburg J, van den Akker T | 2021-07-28 | Afghanistan, Capacity of health services, Medical treatment, Postabortion care, Reproductive health | Reproductive health |
Health-related quality of life and symptoms of conservative care versus dialysis in patients with end-stage kidney disease: a systematic review. | Verberne WR, van den Wittenboer ID, Voorend CGN, Abrahams AC, van Buren M, Dekker FW, van Jaarsveld BC, van Loon IN, Mooijaart SP, Ocak G, van Delden JJM, Bos WJW | 2021-07-23 | conservative care, health-related quality of life, renal dialysis, symptoms, systematic review | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association |
Association of measures of body fat with serum alpha-tocopherol and its metabolites in middle-aged individuals. | Meulmeester FL, Luo J, Martens LG, Ashrafi N, de Mutsert R, Mook-Kanamori DO, Lamb HJ, Rosendaal FR, Willems van Dijk K, Mills K, van Heemst D, Noordam R | 2021-07-22 | Alpha tocopherol, Epidemiology, Mass spectrometry, Obesity, Subcutaneous adipose tissue, Visceral adipose tissue, Vitamin E metabolites | Nutrition, metabolism, and cardiovascular diseases : NMCD |
Implementation of the Multidisciplinary Guideline on Chronic Pain in Vulnerable Nursing Home Residents to Improve Recognition and Treatment: A Qualitative Process Evaluation. | Akker LEVD, Waal MWM, Geels PJEM, Poot E, Achterberg WP | 2021-07-16 | guideline, implementation, nursing home, pain, pain management, pharmacotherapy audit meetings, qualitative research | Healthcare (Basel, Switzerland) |
Dynamic clonal hematopoiesis and functional T-cell immunity in a supercentenarian. | van den Akker EB, Makrodimitris S, Hulsman M, Brugman MH, Nikolic T, Bradley T, Waisfisz Q, Baas F, Jakobs ME, de Jong D, Slagboom PE, Staal FJT, Reinders MJT, Holstege H | 2021-07-01 | Leukemia | |
Apolipoprotein E genotype, lifestyle and coronary artery disease: Gene-environment interaction analyses in the UK Biobank population. | Bos MM, de Vries L, Rensen PC, Willems van Dijk K, Blauw GJ, van Heemst D, Noordam R | 2021-07-01 | APOE, Coronary artery disease, Fish, Gene-environment interactions, General population, PUFA, Physical activity | Atherosclerosis |
Management of major obstetric hemorrhage prior to peripartum hysterectomy and outcomes across nine European countries. | Kallianidis AF, Maraschini A, Danis J, Colmorn LB, Deneux-Tharaux C, Donati S, Gissler M, Jakobsson M, Knight M, Kristufkova A, Lindqvist PG, Vandenberghe G, van den Akker T | 2021-07-01 | hysterectomy, peripartum period, placenta accreta, postpartum hemorrhage, pregnancy complications | Acta obstetricia et gynecologica Scandinavica |
The Bidirectional Relationship between Vision and Cognition: A Systematic Review and Meta-analysis. | Vu TA, Fenwick EK, Gan ATL, Man REK, Tan BKJ, Gupta P, Ho KC, Reyes-Ortiz CA, Trompet S, Gussekloo J, O'Brien JM, Mueller-Schotte S, Wong TY, Tham YC, Cheng CY, Lee ATC, Rait G, Swenor BK, Varadaraj V, Brenowitz WD, Medeiros FA, Naël V, Narasimhalu K, Chen CLH, Lamoureux EL | 2021-07-01 | Bidirectional, Cognitive impairment, Dementia, Visual acuity, Visual impairment | Ophthalmology |
White matter hyperintensities associate with cognitive slowing in patients with systemic lupus erythematosus and neuropsychiatric symptoms. | Monahan RC, Inglese F, Middelkoop H, van Buchem M, Huizinga TW, Kloppenburg M, Ronen I, Steup-Beekman GM, de Bresser J | 2021-07-01 | lupus erythematosus, magnetic resonance imaging, psychology, systemic | RMD open |
Probable Pain on the Pain Assessment in Impaired Cognition (PAIC15) Instrument: Assessing Sensitivity and Specificity of Cut-Offs against Three Standards. | van der Steen JT, Westzaan A, Hanemaayer K, Muhamad M, de Waal MWM, Achterberg WP | 2021-06-29 | behavior observation techniques, dementia, diagnostic techniques and procedures, pain measurement | Brain sciences |
Longitudinal changes in cerebral white matter microstructure in newly diagnosed systemic lupus erythematosus patients. | Silvagni E, Inglese F, Bortoluzzi A, Borrelli M, Goeman JJ, Revenaz A, Groppo E, Steup-Beekman GM, Huizinga TWJ, Ronen I, de Bresser J, Fainardi E, Govoni M, Ercan E | 2021-06-18 | diffusion tensor imaging, longitudinal MRI, systemic lupus erythematosus | Rheumatology (Oxford, England) |
Genetically Determined Higher TSH Is Associated With a Lower Risk of Diabetes Mellitus in Individuals With Low BMI. | Bos MM, van Vliet NA, Mooijaart SP, Noordam R, van Heemst D | 2021-06-16 | diabetes mellitus, glucose homeostasis, hyperthyroidism, hypothyroidism, mendelian randomization, obesity, thyroid function | The Journal of clinical endocrinology and metabolism |
Differential insulin sensitivity of NMR-based metabolomic measures in a two-step hyperinsulinemic euglycemic clamp study. | Wang W, van Dijk KW, Wijsman CA, Rozing MP, Mooijaart SP, Beekman M, Slagboom PE, Jukema JW, Noordam R, van Heemst D | 2021-06-09 | Hyperinsulinemic euglycemic clamp study, Insulin resistance, Metabolomic measures | Metabolomics : Official journal of the Metabolomic Society |
Toxicity, Response and Survival in Older Patients with Metastatic Melanoma Treated with Checkpoint Inhibitors. | de Glas NA, Bastiaannet E, van den Bos F, Mooijaart SP, van der Veldt AAM, Suijkerbuijk KPM, Aarts MJB, van den Berkmortel FWPJ, Blank CU, Boers-Sonderen MJ, van den Eertwegh AJM, de Groot JB, Haanen JBAG, Hospers GAP, Jalving H, Piersma D, van Rijn RS, Ten Tije AJ, Vreugdenhil G, Wouters MWJM, Portielje JEA, Kapiteijn EW | 2021-06-05 | geriatric oncology, immunotherapy, melanoma, older adults, response, toxicity | Cancers |
Ageing affects subtelomeric DNA methylation in blood cells from a large European population enrolled in the MARK-AGE study. | Bacalini MG, Reale A, Malavolta M, Ciccarone F, Moreno-Villanueva M, Dollé MET, Jansen E, Grune T, Gonos ES, Schön C, Bernhardt J, Grubeck-Loebenstein B, Sikora E, Toussaint O, Debacq-Chainiaux F, Capri M, Hervonen A, Hurme M, Slagboom PE, Breusing N, Aversano V, Tagliatesta S, Franceschi C, Blasco MA, Bürkle A, Caiafa P, Zampieri M | 2021-06-01 | Ageing, Centenarian offspring, DNA methylation, Down syndrome, Epigenetics, Subtelomere | GeroScience |
DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan. | van Dongen J, Hagenbeek FA, Suderman M, Roetman PJ, Sugden K, Chiocchetti AG, Ismail K, Mulder RH, Hafferty JD, Adams MJ, Walker RM, Morris SW, Lahti J, Küpers LK, Escaramis G, Alemany S, Jan Bonder M, Meijer M, Ip HF, Jansen R, Baselmans BML, Parmar P, Lowry E, Streit F, Sirignano L, Send TS, Frank J, Jylhävä J, Wang Y, Mishra PP, Colins OF, Corcoran DL, Poulton R, Mill J, Hannon E, Arseneault L, Korhonen T, Vuoksimaa E, Felix JF, Bakermans-Kranenburg MJ, Campbell A, Czamara D, Binder E, Corpeleijn E, Gonzalez JR, Grazuleviciene R, Gutzkow KB, Evandt J, Vafeiadi M, Klein M, van der Meer D, Ligthart L, Kluft C, Davies GE, Hakulinen C, Keltikangas-Järvinen L, Franke B, Freitag CM, Konrad K, Hervas A, Fernández-Rivas A, Vetro A, Raitakari O, Lehtimäki T, Vermeiren R, Strandberg T, Räikkönen K, Snieder H, Witt SH, Deuschle M, Pedersen NL, Hägg S, Sunyer J, Franke L, Kaprio J, Ollikainen M, Moffitt TE, Tiemeier H, van IJzendoorn MH, Relton C, Vrijheid M, Sebert S, Jarvelin MR, Caspi A, Evans KL, McIntosh AM, Bartels M, Boomsma DI | 2021-06-01 | Molecular psychiatry | |
Urinary oxidized, but not enzymatic vitamin E metabolites are inversely associated with measures of glucose homeostasis in middle-aged healthy individuals. | Luo J, Meulmeester FL, Martens LG, Ashrafi N, de Mutsert R, Mook-Kanamori DO, Rosendaal FR, Willems van Dijk K, le Cessie S, Mills K, Noordam R, van Heemst D | 2021-06-01 | Alpha-tocopherol, Glucose homeostasis, Insulin resistance, Vitamin E | Clinical nutrition (Edinburgh, Scotland) |
Genetically Determined Serum Calcium Levels and Markers of Ventricular Repolarization: A Mendelian Randomization Study in the UK Biobank. | Young WJ, Warren HR, Mook-Kanamori DO, Ramírez J, van Duijvenboden S, Orini M, Tinker A, van Heemst D, Lambiase PD, Jukema JW, Munroe PB, Noordam R | 2021-06-01 | action potential, calcium, cardiovascular diseases, electrocardiography, electrolyte | Circulation. Genomic and precision medicine |
The trans-ancestral genomic architecture of glycemic traits. | Chen J, Spracklen CN, Marenne G, Varshney A, Corbin LJ, Luan J, Willems SM, Wu Y, Zhang X, Horikoshi M, Boutin TS, Mägi R, Waage J, Li-Gao R, Chan KHK, Yao J, Anasanti MD, Chu AY, Claringbould A, Heikkinen J, Hong J, Hottenga JJ, Huo S, Kaakinen MA, Louie T, März W, Moreno-Macias H, Ndungu A, Nelson SC, Nolte IM, North KE, Raulerson CK, Ray D, Rohde R, Rybin D, Schurmann C, Sim X, Southam L, Stewart ID, Wang CA, Wang Y, Wu P, Zhang W, Ahluwalia TS, Appel EVR, Bielak LF, Brody JA, Burtt NP, Cabrera CP, Cade BE, Chai JF, Chai X, Chang LC, Chen CH, Chen BH, Chitrala KN, Chiu YF, de Haan HG, Delgado GE, Demirkan A, Duan Q, Engmann J, Fatumo SA, Gayán J, Giulianini F, Gong JH, Gustafsson S, Hai Y, Hartwig FP, He J, Heianza Y, Huang T, Huerta-Chagoya A, Hwang MY, Jensen RA, Kawaguchi T, Kentistou KA, Kim YJ, Kleber ME, Kooner IK, Lai S, Lange LA, Langefeld CD, Lauzon M, Li M, Ligthart S, Liu J, Loh M, Long J, Lyssenko V, Mangino M, Marzi C, Montasser ME, Nag A, Nakatochi M, Noce D, Noordam R, Pistis G, Preuss M, Raffield L, Rasmussen-Torvik LJ, Rich SS, Robertson NR, Rueedi R, Ryan K, Sanna S, Saxena R, Schraut KE, Sennblad B, Setoh K, Smith AV, Sparsø T, Strawbridge RJ, Takeuchi F, Tan J, Trompet S, van den Akker E, van der Most PJ, Verweij N, Vogel M, Wang H, Wang C, Wang N, Warren HR, Wen W, Wilsgaard T, Wong A, Wood AR, Xie T, Zafarmand MH, Zhao JH, Zhao W, Amin N, Arzumanyan Z, Astrup A, Bakker SJL, Baldassarre D, Beekman M, Bergman RN, Bertoni A, Blüher M, Bonnycastle LL, Bornstein SR, Bowden DW, Cai Q, Campbell A, Campbell H, Chang YC, de Geus EJC, Dehghan A, Du S, Eiriksdottir G, Farmaki AE, Frånberg M, Fuchsberger C, Gao Y, Gjesing AP, Goel A, Han S, Hartman CA, Herder C, Hicks AA, Hsieh CH, Hsueh WA, Ichihara S, Igase M, Ikram MA, Johnson WC, Jørgensen ME, Joshi PK, Kalyani RR, Kandeel FR, Katsuya T, Khor CC, Kiess W, Kolcic I, Kuulasmaa T, Kuusisto J, Läll K, Lam K, Lawlor DA, Lee NR, Lemaitre RN, Li H, Lin SY, Lindström J, Linneberg A, Liu J, Lorenzo C, Matsubara T, Matsuda F, Mingrone G, Mooijaart S, Moon S, Nabika T, Nadkarni GN, Nadler JL, Nelis M, Neville MJ, Norris JM, Ohyagi Y, Peters A, Peyser PA, Polasek O, Qi Q, Raven D, Reilly DF, Reiner A, Rivideneira F, Roll K, Rudan I, Sabanayagam C, Sandow K, Sattar N, Schürmann A, Shi J, Stringham HM, Taylor KD, Teslovich TM, Thuesen B, Timmers PRHJ, Tremoli E, Tsai MY, Uitterlinden A, van Dam RM, van Heemst D, van Hylckama Vlieg A, van Vliet-Ostaptchouk JV, Vangipurapu J, Vestergaard H, Wang T, Willems van Dijk K, Zemunik T, Abecasis GR, Adair LS, Aguilar-Salinas CA, Alarcón-Riquelme ME, An P, Aviles-Santa L, Becker DM, Beilin LJ, Bergmann S, Bisgaard H, Black C, Boehnke M, Boerwinkle E, Böhm BO, Bønnelykke K, Boomsma DI, Bottinger EP, Buchanan TA, Canouil M, Caulfield MJ, Chambers JC, Chasman DI, Chen YI, Cheng CY, Collins FS, Correa A, Cucca F, de Silva HJ, Dedoussis G, Elmståhl S, Evans MK, Ferrannini E, Ferrucci L, Florez JC, Franks PW, Frayling TM, Froguel P, Gigante B, Goodarzi MO, Gordon-Larsen P, Grallert H, Grarup N, Grimsgaard S, Groop L, Gudnason V, Guo X, Hamsten A, Hansen T, Hayward C, Heckbert SR, Horta BL, Huang W, Ingelsson E, James PS, Jarvelin MR, Jonas JB, Jukema JW, Kaleebu P, Kaplan R, Kardia SLR, Kato N, Keinanen-Kiukaanniemi SM, Kim BJ, Kivimaki M, Koistinen HA, Kooner JS, Körner A, Kovacs P, Kuh D, Kumari M, Kutalik Z, Laakso M, Lakka TA, Launer LJ, Leander K, Li H, Lin X, Lind L, Lindgren C, Liu S, Loos RJF, Magnusson PKE, Mahajan A, Metspalu A, Mook-Kanamori DO, Mori TA, Munroe PB, Njølstad I, O'Connell JR, Oldehinkel AJ, Ong KK, Padmanabhan S, Palmer CNA, Palmer ND, Pedersen O, Pennell CE, Porteous DJ, Pramstaller PP, Province MA, Psaty BM, Qi L, Raffel LJ, Rauramaa R, Redline S, Ridker PM, Rosendaal FR, Saaristo TE, Sandhu M, Saramies J, Schneiderman N, Schwarz P, Scott LJ, Selvin E, Sever P, Shu XO, Slagboom PE, Small KS, Smith BH, Snieder H, Sofer T, Sørensen TIA, Spector TD, Stanton A, Steves CJ, Stumvoll M, Sun L, Tabara Y, Tai ES, Timpson NJ, Tönjes A, Tuomilehto J, Tusie T, Uusitupa M, van der Harst P, van Duijn C, Vitart V, Vollenweider P, Vrijkotte TGM, Wagenknecht LE, Walker M, Wang YX, Wareham NJ, Watanabe RM, Watkins H, Wei WB, Wickremasinghe AR, Willemsen G, Wilson JF, Wong TY, Wu JY, Xiang AH, Yanek LR, Yengo L, Yokota M, Zeggini E, Zheng W, Zonderman AB, Rotter JI, Gloyn AL, McCarthy MI, Dupuis J, Meigs JB, Scott RA, Prokopenko I, Leong A, Liu CT, Parker SCJ, Mohlke KL, Langenberg C, Wheeler E, Morris AP, Barroso I | 2021-06-01 | Nature genetics | |
The injustice of unfit clinical practice guidelines in low-resource realities. | Maaløe N, Ørtved AMR, Sørensen JB, Sequeira Dmello B, van den Akker T, Kujabi ML, Kidanto H, Meguid T, Bygbjerg IC, van Roosmalen J, Meyrowitsch DW, Housseine N | 2021-06-01 | The Lancet. Global health | |
Predicting disease-related and patient-reported outcomes in older patients with breast cancer – a systematic review. | van der Plas-Krijgsman WG, de Boer AZ, de Jong P, Bastiaannet E, van den Bos F, Mooijaart SP, Liefers GJ, Portielje JEA, de Glas NA | 2021-06-01 | Breast cancer, Geriatric assessment, Geriatric oncology, Prediction | Journal of geriatric oncology |
Prognostic Factors for Short-term Recovery of Independence in a Multistate Model for Patients With a Hip Fracture. | van der Sijp MPL, van Eijk M, Niggebrugge AHP, Putter H, Blauw GJ, Achterberg WP | 2021-06-01 | Hip fracture, independence, multistate, older patients, recovery, survival | Journal of the American Medical Directors Association |
Management of prolonged first stage of labour in a low-resource setting: lessons learnt from rural Malawi. | Bakker W, van Dorp E, Kazembe M, Nkotola A, van Roosmalen J, van den Akker T | 2021-05-22 | Amniotomy, Augmentation of labour, Caesarean section, Cephalopelvic disproportion, Prolonged labour | BMC pregnancy and childbirth |
Frailty is associated with in-hospital mortality in older hospitalised COVID-19 patients in the Netherlands: the COVID-OLD study. | Blomaard LC, van der Linden CMJ, van der Bol JM, Jansen SWM, Polinder-Bos HA, Willems HC, Festen J, Barten DG, Borgers AJ, Bos JC, van den Bos F, de Brouwer EJM, van Deudekom FJA, van Dijk SC, Emmelot-Vonk MH, Geels RES, van de Glind EMM, de Groot B, Hempenius L, Kamper AM, Kampschreur LM, de Koning MMM, Labots G, Looman R, Lucke JA, Maas HAAM, Mattace-Raso FUS, El Moussaoui R, van Munster BC, van Nieuwkoop C, Oosterwijk LBLE, Regtuijt MEM, Robben SHM, Ruiter R, Salarbaks AM, Schouten HJ, Smit OM, Smits RAL, Spies PE, Vreeswijk R, de Vries OJ, Wijngaarden MA, Wyers CE, Mooijaart SP | 2021-05-05 | COVID-19, SARS-CoV-2, clinical frailty scale, frailty, older adults | Age and ageing |
The impact of pain on the course of ADL functioning in patients with dementia. | van Dalen-Kok AH, Pieper MJC, de Waal MWM, van der Steen JT, Scherder EJA, Achterberg WP | 2021-05-05 | activities of daily living, dementia, longitudinal study, nursing home, older people, pain | Age and ageing |
The COVID rehabilitation paradox: why we need to protect and develop geriatric rehabilitation services in the face of the pandemic. | Grund S, Gordon AL, Bauer JM, Achterberg WP, Schols JMGA | 2021-05-05 | COVID-19, Geriatric Rehabilitation, Pandemic, Paradoxon, older people | Age and ageing |
Metabolic biomarker profiling for identification of susceptibility to severe pneumonia and COVID-19 in the general population. | Julkunen H, Cichońska A, Slagboom PE, Würtz P | 2021-05-04 | biomarkers, covid-19, epidemiology, global health, human, medicine, pneumonia | eLife |
Lifestyle Risk Score: handling missingness of individual lifestyle components in meta-analysis of gene-by-lifestyle interactions. | Xu H, Schwander K, Brown MR, Wang W, Waken RJ, Boerwinkle E, Cupples LA, de Las Fuentes L, van Heemst D, Osazuwa-Peters O, de Vries PS, van Dijk KW, Sung YJ, Zhang X, Morrison AC, Rao DC, Noordam R, Liu CT | 2021-05-01 | European journal of human genetics : EJHG | |
Status of institutional-level respectful maternity care: Results from the national Ethiopia EmONC assessment. | Sheferaw ED, Bakker R, Taddele T, Geta A, Kim YM, van den Akker T, Stekelenburg J | 2021-05-01 | Ethiopia, Mistreatment, Respectful maternity care | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics |
Clinical determinants of low handgrip strength and its decline in the oldest old: the Leiden 85-plus Study. | Ling CHY, Gussekloo J, Trompet S, Meskers CGM, Maier AB | 2021-05-01 | Cognitive function, Muscle strength, Physical fitness, Sex differences | Aging clinical and experimental research |
Preoperative MRI brain phenotypes are related to postoperative delirium in older individuals. | Kant IMJ, Slooter AJC, Jaarsma-Coes M, van Montfort SJT, Witkamp TD, Pasma W, Hendrikse J, de Bresser J | 2021-05-01 | Brain phenotypes, Delirium, Encephalopathy, MRI | Neurobiology of aging |
Daily garden use and quality of life in persons with advanced dementia living in a nursing home: A feasibility study. | van der Velde-van Buuringen M, Achterberg WP, Caljouw MAA | 2021-05-01 | behaviour, dementia, gardens, nursing homes, quality of life | Nursing open |
Genome-wide association study of circulating interleukin 6 levels identifies novel loci. | Ahluwalia TS, Prins BP, Abdollahi M, Armstrong NJ, Aslibekyan S, Bain L, Jefferis B, Baumert J, Beekman M, Ben-Shlomo Y, Bis JC, Mitchell BD, de Geus E, Delgado GE, Marek D, Eriksson J, Kajantie E, Kanoni S, Kemp JP, Lu C, Marioni RE, McLachlan S, Milaneschi Y, Nolte IM, Petrelis AM, Porcu E, Sabater-Lleal M, Naderi E, Seppälä I, Shah T, Singhal G, Standl M, Teumer A, Thalamuthu A, Thiering E, Trompet S, Ballantyne CM, Benjamin EJ, Casas JP, Toben C, Dedoussis G, Deelen J, Durda P, Engmann J, Feitosa MF, Grallert H, Hammarstedt A, Harris SE, Homuth G, Hottenga JJ, Jalkanen S, Jamshidi Y, Jawahar MC, Jess T, Kivimaki M, Kleber ME, Lahti J, Liu Y, Marques-Vidal P, Mellström D, Mooijaart SP, Müller-Nurasyid M, Penninx B, Revez JA, Rossing P, Räikkönen K, Sattar N, Scharnagl H, Sennblad B, Silveira A, Pourcain BS, Timpson NJ, Trollor J, van Dongen J, Van Heemst D, Visvikis-Siest S, Vollenweider P, Völker U, Waldenberger M, Willemsen G, Zabaneh D, Morris RW, Arnett DK, Baune BT, Boomsma DI, Chang YC, Deary IJ, Deloukas P, Eriksson JG, Evans DM, Ferreira MA, Gaunt T, Gudnason V, Hamsten A, Heinrich J, Hingorani A, Humphries SE, Jukema JW, Koenig W, Kumari M, Kutalik Z, Lawlor DA, Lehtimäki T, März W, Mather KA, Naitza S, Nauck M, Ohlsson C, Price JF, Raitakari O, Rice K, Sachdev PS, Slagboom E, Sørensen TIA, Spector T, Stacey D, Stathopoulou MG, Tanaka T, Wannamethee SG, Whincup P, Rotter JI, Dehghan A, Boerwinkle E, Psaty BM, Snieder H, Alizadeh BZ | 2021-04-27 | Human molecular genetics | |
Association of White Matter Hyperintensity Markers on MRI and Long-term Risk of Mortality and Ischemic Stroke: The SMART-MR Study. | Ghaznawi R, Geerlings MI, Jaarsma-Coes M, Hendrikse J, de Bresser J | 2021-04-27 | Neurology | |
Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes. | Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X, Wojczynski MK, Biggs ML, van der Spek A, Atzmon G, Ware EB, Sarnowski C, Smith AV, Seppälä I, Cordell HJ, Dose J, Amin N, Arnold AM, Ayers KL, Barzilai N, Becker EJ, Beekman M, Blanché H, Christensen K, Christiansen L, Collerton JC, Cubaynes S, Cummings SR, Davies K, Debrabant B, Deleuze JF, Duncan R, Faul JD, Franceschi C, Galan P, Gudnason V, Harris TB, Huisman M, Hurme MA, Jagger C, Jansen I, Jylhä M, Kähönen M, Karasik D, Kardia SLR, Kingston A, Kirkwood TBL, Launer LJ, Lehtimäki T, Lieb W, Lyytikäinen LP, Martin-Ruiz C, Min J, Nebel A, Newman AB, Nie C, Nohr EA, Orwoll ES, Perls TT, Province MA, Psaty BM, Raitakari OT, Reinders MJT, Robine JM, Rotter JI, Sebastiani P, Smith J, Sørensen TIA, Taylor KD, Uitterlinden AG, van der Flier W, van der Lee SJ, van Duijn CM, van Heemst D, Vaupel JW, Weir D, Ye K, Zeng Y, Zheng W, Holstege H, Kiel DP, Lunetta KL, Slagboom PE, Murabito JM | 2021-04-23 | Nature communications | |
Practitioners’ perceptions of acceptability of a question prompt list about palliative care for advance care planning with people living with dementia and their family caregivers: a mixed-methods evaluation study. | van der Steen JT, Heck S, Juffermans CC, Garvelink MM, Achterberg WP, Clayton J, Thompson G, Koopmans RT, van der Linden YM | 2021-04-12 | adult palliative care, dementia, geriatric medicine | BMJ open |
A European Research Agenda for Geriatric Emergency Medicine: a modified Delphi study. | Mooijaart SP, Nickel CH, Conroy SP, Lucke JA, van Tol LS, Olthof M, Blomaard LC, Buurman BM, Dundar ZD, de Groot B, Gasperini B, Heeren P, Karamercan MA, McNamara R, Mitchell A, van Oppen JD, Martin Sanchez FJ, Schoon Y, Singler K, Spode R, Skúldóttir S, Thorrsteindottir T, van der Velde M, Wallace J | 2021-04-01 | Geriatric Emergency Medicine, Research prioritisation | European geriatric medicine |
Outcomes of Thyroid Dysfunction in People Aged Eighty Years and Older: An Individual Patient Data Meta-Analysis of Four Prospective Studies (Towards Understanding Longitudinal International Older People Studies Consortium). | Du Puy RS, Poortvliet RKE, Mooijaart SP, den Elzen WPJ, Jagger C, Pearce SHS, Arai Y, Hirose N, Teh R, Menzies O, Rolleston A, Kerse N, Gussekloo J | 2021-04-01 | IPD-MA, function, mortality, oldest old, thyroid dysfunction | Thyroid : official journal of the American Thyroid Association |
Mapping the multicausality of Alzheimer’s disease through group model building. | Uleman JF, Melis RJF, Quax R, van der Zee EA, Thijssen D, Dresler M, van de Rest O, van der Velpen IF, Adams HHH, Schmand B, de Kok IMCM, de Bresser J, Richard E, Verbeek M, Hoekstra AG, Rouwette EAJA, Olde Rikkert MGM | 2021-04-01 | Alzheimer’s disease, Causal loop diagram, Centrality, Complexity, Group model building, Multicausal, Systems thinking | GeroScience |
Feasibility of a multicomponent cognitive behavioral intervention for fear of falling after hip fracture: process evaluation of the FIT-HIP intervention. | Scheffers-Barnhoorn MN, van Eijk M, Schols JMGA, van Balen R, Kempen GIJM, Achterberg WP, van Haastregt JCM | 2021-04-01 | Cognitive behavioral intervention, Fear of falling, Feasibility, Geriatric rehabilitation, Hip fracture, Process evaluation | BMC geriatrics |
Health workers’ perspectives on informed consent for caesarean section in Southern Malawi. | Bakker W, Zethof S, Nansongole F, Kilowe K, van Roosmalen J, van den Akker T | 2021-03-29 | BMC medical ethics | |
Correction to: DIALysis or not: Outcomes in older kidney patients with GerIatriC Assessment (DIALOGICA): rationale and design. | van Oevelen M, Abrahams AC, Bos WJW, Emmelot-Vonk MH, Mooijaart SP, van Diepen M, van Jaarsveld BC, van Eck van der Sluijs A, Voorend CGN, van Buren M | 2021-03-29 | BMC nephrology | |
Experiences with and attitudes towards geriatric screening among older emergency department patients: a qualitative study. | Blomaard LC, Olthof M, Meuleman Y, de Groot B, Gussekloo J, Mooijaart SP | 2021-03-20 | Emergency medicine, Frailty, Frailty screening, Older adults, Qualitative research | BMC geriatrics |
Investigating the relationships between unfavourable habitual sleep and metabolomic traits: evidence from multi-cohort multivariable regression and Mendelian randomization analyses. | Bos MM, Goulding NJ, Lee MA, Hofman A, Bot M, Pool R, Vijfhuizen LS, Zhang X, Li C, Mustafa R, Neville MJ, Li-Gao R, Trompet S, Beekman M, Biermasz NR, Boomsma DI, de Boer I, Christodoulides C, Dehghan A, van Dijk KW, Ford I, Ghanbari M, Heijmans BT, Ikram MA, Jukema JW, Mook-Kanamori DO, Karpe F, Luik AI, Lumey LH, van den Maagdenberg AMJM, Mooijaart SP, de Mutsert R, Penninx BWJH, Rensen PCN, Richmond RC, Rosendaal FR, Sattar N, Schoevers RA, Slagboom PE, Terwindt GM, Thesing CS, Wade KH, Wijsman CA, Willemsen G, Zwinderman AH, van Heemst D, Noordam R, Lawlor DA | 2021-03-18 | Epidemiology, Mendelian randomization, Metabolomics, Sleep | BMC medicine |
Self-rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains. | Kananen L, Enroth L, Raitanen J, Jylhävä J, Bürkle A, Moreno-Villanueva M, Bernhardt J, Toussaint O, Grubeck-Loebenstein B, Malavolta M, Basso A, Piacenza F, Collino S, Gonos ES, Sikora E, Gradinaru D, Jansen EHJM, Dollé MET, Salmon M, Stuetz W, Weber D, Grune T, Breusing N, Simm A, Capri M, Franceschi C, Slagboom PE, Talbot DCS, Libert C, Koskinen S, Bruunsgaard H, Hansen ÅM, Lund R, Hurme M, Jylhä M | 2021-03-17 | Scientific reports | |
Correction for both common and rare cell types in blood is important to identify genes that correlate with age. | Pellegrino-Coppola D, Claringbould A, Stutvoet M, Boomsma DI, Ikram MA, Slagboom PE, Westra HJ, Franke L | 2021-03-15 | Aging, Cell counts correction, Gene expression, Platelet activity, Whole blood | BMC genomics |
Geriatric screening, fall characteristics and 3- and 12 months adverse outcomes in older patients visiting the emergency department with a fall. | Blomaard LC, Mooijaart SP, van Meer LJ, Leander J, Lucke JA, de Gelder J, Anten S, Gussekloo J, de Groot B | 2021-03-04 | Aged, Falls, Frailty, Geriatric emergency medicine, Older adults | Scandinavian journal of trauma, resuscitation and emergency medicine |
Families in comparison: An individual-level comparison of life-course and family reconstructions between population and vital event registers. | van den Berg N, van Dijk IK, Mourits RJ, Slagboom PE, Janssens AAPO, Mandemakers K | 2021-03-01 | civil registers, databases, demographic methods, family history, family reconstitutions, family reconstruction, historical demography, life course, microdata, population registers | Population studies |
Common Genetic Variation in MC4R Does Not Affect Atherosclerotic Plaque Phenotypes and Cardiovascular Disease Outcomes. | Blauw LL, Noordam R, van der Laan SW, Trompet S, Kooijman S, van Heemst D, Jukema JW, van Setten J, de Borst GJ, Tybjærg-Hansen A, Pasterkamp G, Berbée JFP, Rensen PCN | 2021-03-01 | BMI, MC4R, atherosclerosis, cardiovascular disease, genetics | Journal of clinical medicine |
Association between Clinical Frailty Scale score and hospital mortality in adult patients with COVID-19 (COMET): an international, multicentre, retrospective, observational cohort study. | Sablerolles RSG, Lafeber M, van Kempen JAL, van de Loo BPA, Boersma E, Rietdijk WJR, Polinder-Bos HA, Mooijaart SP, van der Kuy H, Versmissen J, Faes MC | 2021-03-01 | The lancet. Healthy longevity | |
Improving the care for older emergency department patients: the Acutely Presenting Older Patient study. | Mooijaart SP | 2021-03-01 | Zeitschrift fur Gerontologie und Geriatrie | |
Implementation of the acutely presenting older patient (APOP) screening program in routine emergency department care : A before-after study. | Blomaard LC, de Groot B, Lucke JA, de Gelder J, Booijen AM, Gussekloo J, Mooijaart SP | 2021-03-01 | Frail elderly, Geriatric assessment, Geriatric emergency medicine, Implementation science, Quality improvement | Zeitschrift fur Gerontologie und Geriatrie |
The Association Between Pain Perception and Care Dependency in Older Nursing Home Residents: A Prospective Cohort Study. | Steenbeek ED, Ramspek CL, van Diepen M, Dekker FW, Achterberg WP | 2021-03-01 | Pain, care dependency, cognitive performance, nursing homes, older | Journal of the American Medical Directors Association |
Perceptions of Factors Leading to Teenage Pregnancy in Lindi Region, Tanzania: A Grounded Theory Study. | Te Lindert L, van der Deijl M, Elirehema A, van Elteren-Jansen M, Chitanda R, van den Akker T | 2021-02-22 | The American journal of tropical medicine and hygiene | |
The effect of a telephone follow-up call for older patients, discharged home from the emergency department on health-related outcomes: a systematic review of controlled studies. | van Loon-van Gaalen M, van Winsen B, van der Linden MC, Gussekloo J, van der Mast RC | 2021-02-18 | Emergency department, Geriatric, Older patients, Postdischarge follow-up, Telephone | International journal of emergency medicine |
Iron loading is a prominent feature of activated microglia in Alzheimer’s disease patients. | Kenkhuis B, Somarakis A, de Haan L, Dzyubachyk O, IJsselsteijn ME, de Miranda NFCC, Lelieveldt BPF, Dijkstra J, van Roon-Mom WMC, Höllt T, van der Weerd L | 2021-02-17 | Alzheimer, Ferritin, Human, Iron, Microglia | Acta neuropathologica communications |
Family Planning Uptake in Kagera and Mara Regions in Tanzania: A Cross-Sectional Community Survey. | Massenga J, Noronha R, Awadhi B, Bishanga D, Safari O, Njonge L, Kim YM, Roosmalen JV, van den Akker T | 2021-02-09 | antenatal care, childbirth, community health worker, facility health care worker, family planning, male partner | International journal of environmental research and public health |
[From healthy individuals to healthy populations]. | van de Vijver PL, van Bodegom D | 2021-02-04 | Nederlands tijdschrift voor geneeskunde | |
Associations of Cytomegalovirus Infection With All-Cause and Cardiovascular Mortality in Multiple Observational Cohort Studies of Older Adults. | Chen S, Pawelec G, Trompet S, Goldeck D, Mortensen LH, Slagboom PE, Christensen K, Gussekloo J, Kearney P, Buckley BM, Ford I, Jukema JW, Westendorp RGJ, Maier AB | 2021-02-03 | Herpesviridae, aged, cardiovascular, cytomegalovirus, immunoglobulin G, mortality, seroepidemiologic studies | The Journal of infectious diseases |
Detailed immune monitoring of a pregnant woman with critical Covid-19. | du Fossé NA, Bronsgeest K, Arbous MS, Zlei M, Myeni SK, Kikkert M, van Dongen J, Staal F, van der Hoorn M, van den Akker T | 2021-02-01 | Covid-19, Flow cytometry, Immune monitoring, Pregnancy | Journal of reproductive immunology |
Cost-utility and cost-effectiveness analysis of a clinical medication review focused on personal goals in older persons with polypharmacy compared to usual care: Economic evaluation of the DREAMeR study. | Verdoorn S, van de Pol J, Hövels AM, Kwint HF, Blom JW, Gussekloo J, Bouvy ML | 2021-02-01 | clinical medication review, cost-effectiveness, older persons, polypharmacy, primary care, randomised controlled trial | British journal of clinical pharmacology |
Effect of Levothyroxine Therapy on the Development of Depressive Symptoms in Older Adults With Subclinical Hypothyroidism: An Ancillary Study of a Randomized Clinical Trial. | Wildisen L, Feller M, Del Giovane C, Moutzouri E, Du Puy RS, Mooijaart SP, Collet TH, Poortvliet RKE, Kearney P, Quinn TJ, Klöppel S, Bauer DC, Peeters RP, Westendorp R, Aujesky D, Gussekloo J, Rodondi N | 2021-02-01 | JAMA network open | |
Letter to Kawijara et al.: Letter in response to “Effects of Caregiver Dementia Training in Caregiver-Patient Dyads”. | Birkenhäger-Gillesse EG, Achterberg WP, Zuidema SU | 2021-02-01 | caregiver, dementia, psychological intervention, training | International journal of geriatric psychiatry |
Frailty is associated with in-hospital mortality in older hospitalised COVID-19 patients in the Netherlands: the COVID-OLD study | Blomaard LC, van der Linden CMJ, van der Bol JM, Jansen SWM, Polinder-Bos HA, Willems HC, Festen J, Barten DG, Borgers AJ, Bos JC, van den Bos F, de Brouwer EJM, van Deudekom FJA, van Dijk SC, Emmelot-Vonk MH, Geels RES, van de Glind EMM, de Groot B, Hempenius L, Kamper AM, Kampschreur LM, de Koning MMM, Labots G, Looman R, Lucke JA, Maas HAAM, Mattace-Raso FUS, el Moussaoui R, van Munster BC, van Nieuwkoop C, Oosterwijk L(LE, Regtuijt M(M, Robben SHM, Ruiter R, Salarbaks AM, Schouten HJ, Smit OM, Smits RAL, Spies PE, Vreeswijk R, de Vries OJ, Wijngaarden MA, Wyers CE, Mooijaart SP | 2021-01-30 | Age and Ageing | |
DIALysis or not: Outcomes in older kidney patients with GerIatriC Assessment (DIALOGICA): rationale and design. | van Oevelen M, Abrahams AC, Bos WJW, Emmelot-Vonk MH, Mooijaart SP, van Diepen M, van Jaarsveld BC, van Eck van der Sluijs A, Voorend CGN, van Buren M | 2021-01-23 | Costs and cost analysis, Dialysis, Frailty, geriatric assessment, Kidney failure, chronic, Mortality, Quality of life | BMC nephrology |
Understanding the perspectives and values of midwives, obstetricians and obstetric registrars regarding episiotomy: qualitative interview study. | Seijmonsbergen-Schermers A, Thompson S, Feijen-de Jong E, Smit M, Prins M, van den Akker T, de Jonge A | 2021-01-13 | obstetrics, perinatology, qualitative research | BMJ open |
Anaemia and physical and mental health in the very old: An individual participant data meta-analysis of four longitudinal studies of ageing. | Palapar L, Kerse N, Rolleston A, den Elzen WPJ, Gussekloo J, Blom JW, Robinson L, Martin-Ruiz C, Duncan R, Arai Y, Takayama M, Teh R | 2021-01-08 | 80 and over, Activities of daily living, Aged, Anaemia, Cognitive function, Depression | Age and ageing |
Design and rationale of a routine clinical care pathway and prospective cohort study in older patients needing intensive treatment. | van Holstein Y, van Deudekom FJ, Trompet S, Postmus I, Uit den Boogaard A, van der Elst MJT, de Glas NA, van Heemst D, Labots G, Altena M, Slingerland M, Liefers GJ, van den Bos F, van der Bol JM, Blauw GJ, Portielje JEA, Mooijaart SP | 2021-01-07 | Aortic valve replacement, Colon cancer, Comprehensive geriatric assessment, Frailty, Geriatric oncology, Head and neck cancer, Oesophageal cancer, Older patients, Study protocol | BMC geriatrics |
General practitioners’ deprescribing decisions in older adults with polypharmacy: a case vignette study in 31 countries. | Jungo KT, Mantelli S, Rozsnyai Z, Missiou A, Kitanovska BG, Weltermann B, Mallen C, Collins C, Bonfim D, Kurpas D, Petrazzuoli F, Dumitra G, Thulesius H, Lingner H, Johansen KL, Wallis K, Hoffmann K, Peremans L, Pilv L, Šter MP, Bleckwenn M, Sattler M, van der Ploeg M, Torzsa P, Kánská PB, Vinker S, Assenova R, Bravo RG, Viegas RPA, Tsopra R, Pestic SK, Gintere S, Koskela TH, Lazic V, Tkachenko V, Reeve E, Luymes C, Poortvliet RKE, Rodondi N, Gussekloo J, Streit S | 2021-01-07 | Deprescribing, Multimorbidity, Old age, Polypharmacy, Primary health care | BMC geriatrics |
Perspectives and experiences of patients and healthcare professionals with geriatric assessment in chronic kidney disease: a qualitative study. | Voorend CGN, Berkhout-Byrne NC, Meuleman Y, Mooijaart SP, Bos WJW, van Buren M | 2021-01-06 | Chronic kidney failure, Decision making, shared, ESRD, Focus groups, Frail older adults, Geriatric assessment, Qualitative research, Quality of life | BMC nephrology |
Diet-Derived Circulating Antioxidants and Risk of Coronary Heart Disease: A Mendelian Randomization Study. | Luo J, le Cessie S, van Heemst D, Noordam R | 2021-01-05 | Mendelian randomization, antioxidant, coronary heart disease | Journal of the American College of Cardiology |
Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. | Munn-Chernoff MA, Johnson EC, Chou YL, Coleman JRI, Thornton LM, Walters RK, Yilmaz Z, Baker JH, Hübel C, Gordon S, Medland SE, Watson HJ, Gaspar HA, Bryois J, Hinney A, Leppä VM, Mattheisen M, Ripke S, Yao S, Giusti-Rodríguez P, Hanscombe KB, Adan RAH, Alfredsson L, Ando T, Andreassen OA, Berrettini WH, Boehm I, Boni C, Boraska Perica V, Buehren K, Burghardt R, Cassina M, Cichon S, Clementi M, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, Davis OSP, de Zwaan M, Dedoussis G, Degortes D, DeSocio JE, Dick DM, Dikeos D, Dina C, Dmitrzak-Weglarz M, Docampo E, Duncan LE, Egberts K, Ehrlich S, Escaramís G, Esko T, Estivill X, Farmer A, Favaro A, Fernández-Aranda F, Fichter MM, Fischer K, Föcker M, Foretova L, Forstner AJ, Forzan M, Franklin CS, Gallinger S, Giegling I, Giuranna J, Gonidakis F, Gorwood P, Gratacos Mayora M, Guillaume S, Guo Y, Hakonarson H, Hatzikotoulas K, Hauser J, Hebebrand J, Helder SG, Herms S, Herpertz-Dahlmann B, Herzog W, Huckins LM, Hudson JI, Imgart H, Inoko H, Janout V, Jiménez-Murcia S, Julià A, Kalsi G, Kaminská D, Karhunen L, Karwautz A, Kas MJH, Kennedy JL, Keski-Rahkonen A, Kiezebrink K, Kim YR, Klump KL, Knudsen GPS, La Via MC, Le Hellard S, Levitan RD, Li D, Lilenfeld L, Lin BD, Lissowska J, Luykx J, Magistretti PJ, Maj M, Mannik K, Marsal S, Marshall CR, Mattingsdal M, McDevitt S, McGuffin P, Metspalu A, Meulenbelt I, Micali N, Mitchell K, Monteleone AM, Monteleone P, Nacmias B, Navratilova M, Ntalla I, O'Toole JK, Ophoff RA, Padyukov L, Palotie A, Pantel J, Papezova H, Pinto D, Rabionet R, Raevuori A, Ramoz N, Reichborn-Kjennerud T, Ricca V, Ripatti S, Ritschel F, Roberts M, Rotondo A, Rujescu D, Rybakowski F, Santonastaso P, Scherag A, Scherer SW, Schmidt U, Schork NJ, Schosser A, Seitz J, Slachtova L, Slagboom PE, Slof-Op't Landt MCT, Slopien A, Sorbi S, Świątkowska B, Szatkiewicz JP, Tachmazidou I, Tenconi E, Tortorella A, Tozzi F, Treasure J, Tsitsika A, Tyszkiewicz-Nwafor M, Tziouvas K, van Elburg AA, van Furth EF, Wagner G, Walton E, Widen E, Zeggini E, Zerwas S, Zipfel S, Bergen AW, Boden JM, Brandt H, Crawford S, Halmi KA, Horwood LJ, Johnson C, Kaplan AS, Kaye WH, Mitchell J, Olsen CM, Pearson JF, Pedersen NL, Strober M, Werge T, Whiteman DC, Woodside DB, Grove J, Henders AK, Larsen JT, Parker R, Petersen LV, Jordan J, Kennedy MA, Birgegård A, Lichtenstein P, Norring C, Landén M, Mortensen PB, Polimanti R, McClintick JN, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Degenhardt F, Docherty AR, Edwards AC, Foo JC, Fox L, Frank J, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Hodgkinson C, Hoffmann P, Hottenga JJ, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Peterson RE, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG, Zhou H, Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Frye MA, Gäebel W, Hayward C, Ising M, Keyes M, Kiefer F, Koller G, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Männistö S, Müller-Myhsok B, Murray AD, Nurnberger JI, Preuss U, Räikkönen K, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt SH, Wodarz N, Zill P, Adkins DE, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Costello EJ, de Wit H, Diazgranados N, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Hesselbrock V, Hewitt JK, Hopfer CJ, Iacono WG, Johnson EO, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lind PA, McGue M, MacKillop J, Madden PAF, Maes HH, Magnusson PKE, Nelson EC, Nöthen MM, Palmer AA, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose RJ, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Wade TD, Heath AC, Montgomery GW, Martin NG, Sullivan PF, Kaprio J, Breen G, Gelernter J, Edenberg HJ, Bulik CM, Agrawal A | 2021-01-01 | eating disorders, genetic correlation, substance use | Addiction biology |
Microbiome in Blood Samples From the General Population Recruited in the MARK-AGE Project: A Pilot Study. | D'Aquila P, Giacconi R, Malavolta M, Piacenza F, Bürkle A, Villanueva MM, Dollé MET, Jansen E, Grune T, Gonos ES, Franceschi C, Capri M, Grubeck-Loebenstein B, Sikora E, Toussaint O, Debacq-Chainiaux F, Hervonen A, Hurme M, Slagboom PE, Schön C, Bernhardt J, Breusing N, Passarino G, Provinciali M, Bellizzi D | 2021-01-01 | 16S rRNA gene, aging, blood microbiome, free fatty acids, geographic origin, glucose, insulin, leukocytes | Frontiers in microbiology |
Variants of FOXO3 and RPA3 genes affecting IGF-1 levels alter the risk of development of primary osteoarthritis. | Pelsma ICM, Claessen KMJA, Slagboom PE, van Heemst D, Pereira AM, Kroon HM, Ramos YFM, Kloppenburg M, Biermasz NR, Meulenbelt IM | 2021-01-01 | European journal of endocrinology | |
Within-Person Variation in Serum Thyrotropin Concentrations: Main Sources, Potential Underlying Biological Mechanisms, and Clinical Implications. | van der Spoel E, Roelfsema F, van Heemst D | 2021-01-01 | ageing, biological variation, circadian rhythm, seasonality, thyroid-stimulating hormone, thyrotropin, within-person variation | Frontiers in endocrinology |
Determining the frequency of thyroid parameter measurements following rhTSH administration in a healthy, older population. | Zutinic A, Blauw GJ, van Heemst D | 2021-01-01 | Blood sampling, Geriatrics, Longevity, Thyroid, rhTSH | MethodsX |
Images in cytology: Fine needle aspiration cytology of BRAFV600E positive anaplastic thyroid carcinoma. | Xing MH, van den Akker T, Gonzalez-Velazquez C, Urken ML, Chen H | 2021-01-01 | Diagnostic cytopathology | |
Transfusion reactions associated with COVID-19 convalescent plasma therapy for SARS-CoV-2. | Nguyen FT, van den Akker T, Lally K, Lam H, Lenskaya V, Liu STH, Bouvier NM, Aberg JA, Rodriguez D, Krammer F, Strauss D, Shaz BH, Rudon L, Galdon P, Jhang JS, Arinsburg SA, Baine I | 2021-01-01 | FFP transfusion, immunology (other than RBC serology), transfusion practices (adult) | Transfusion |
Learning from changes concurrent with implementing a complex and dynamic intervention to improve urban maternal and perinatal health in Dar es Salaam, Tanzania, 2011-2019. | Sequeira Dmello B, Sellah Z, Magembe G, Housseine N, Maaløe N, van den Akker T, Meyrowitsch DW, Mushi T, Masweko M, Jidayi D, van Roosmalen J, Kidanto HL | 2021-01-01 | health services research, intervention study, maternal health, public health | BMJ global health |
A total blood volume or more transfused during pregnancy or after childbirth: Individual patient data from six international population-based observational studies. | McCall SJ, Henriquez D, Edwards HM, van den Akker T, Bloemenkamp KWM, van der Bom J, Bonnet MP, Deneux-Tharaux C, Donati S, Gillissen A, Kurinczuk JJ, Li Z, Maraschini A, Seco A, Sullivan E, Stanworth S, Knight M | 2021-01-01 | PloS one | |
Quality of Maternal Death Documentation in Afghanistan: A Retrospective Health Facility Record Review. | Maruf F, Tappis H, Stekelenburg J, van den Akker T | 2021-01-01 | Afghanistan, maternal health, maternal mortality, medical records, pregnancy related death, quality of documentation | Frontiers in global women's health |
Interplay of circulating leptin and obesity in cognition and cerebral volumes in older adults. | Zonneveld MH, Noordam R, van der Grond J, van Heemst D, Mooijaart SP, Sabayan B, Jukema JW, Trompet S | 2021-01-01 | BMI, Cardiovascular disease, Cerebral volumes, Circulating leptin, Cognitive dysfunction, Older adults | Peptides |
Correction: Statin Use and Self-Reported Hindering Muscle Complaints in Older Persons: A Population Based Study. | van der Ploeg MA, Poortvliet RKE, van Blijswijk SCE, den Elzen WPJ, van Peet PG, Ruijter W, Blom JW, Gussekloo J | 2021-01-01 | PloS one | |
Levothyroxine Treatment and Cardiovascular Outcomes in Older People With Subclinical Hypothyroidism: Pooled Individual Results of Two Randomised Controlled Trials. | Zijlstra LE, Jukema JW, Westendorp RGJ, Du Puy RS, Poortvliet RKE, Kearney PM, O'Keeffe L, Dekkers OM, Blum MR, Rodondi N, Collet TH, Quinn TJ, Sattar N, Stott DJ, Trompet S, den Elzen WPJ, Gussekloo J, Mooijaart SP | 2021-01-01 | cardiovascular disease, levothyroxine, older adults, randomised controlled trial, subclinical hypothyroidism | Frontiers in endocrinology |
Evaluation of High Cholesterol and Risk of Dementia and Cognitive Decline in Older Adults Using Individual Patient Meta-Analysis. | Peters R, Xu Y, Antikainen R, Beckett N, Gussekloo J, Jagger C, Jukema JW, Keinanen-Kiukaanniemi S, Rydén L, Skoog I, Staessen JA, Thijs L, Trompet S, Tully PJ, Tzourio C, Anstey KJ | 2021-01-01 | Ageing, Cholesterol, Cognitive decline, Dementia | Dementia and geriatric cognitive disorders |
Hypertensive Exposure Markers by MRI in Relation to Cerebral Small Vessel Disease and Cognitive Impairment. | Amier RP, Marcks N, Hooghiemstra AM, Nijveldt R, van Buchem MA, de Roos A, Biessels GJ, Kappelle LJ, van Oostenbrugge RJ, van der Geest RJ, Bots ML, Greving JP, Niessen WJ, van Osch MJP, de Bresser J, van de Ven PM, van der Flier WM, Brunner-La Rocca HP, van Rossum AC | 2021-01-01 | cognition, left ventricular mass, left ventricular mass-to-volume ratio, pulse wave velocity, vascular brain injury | JACC. Cardiovascular imaging |
Preoperative brain MRI features and occurrence of postoperative delirium. | Kant IMJ, de Bresser J, van Montfort SJT, Mutsaerts HJMM, Witkamp TD, Buijsrogge M, Spies C, Hendrikse J, Slooter AJC | 2021-01-01 | Cortical infarcts, Delirium, MRI markers, White matter hyperintensities | Journal of psychosomatic research |
The association between intraoperative hyperglycemia and cerebrovascular markers. | Knaak C, Kant IM, Lammers-Lietz F, Spies C, Witkamp TD, Winterer G, Lachmann G, de Bresser J | 2021-01-01 | Intraoperative hyperglycemia, Neuroimaging MRI, cerebral small vessel disease, perfusion, vascular lesions. | International journal of medical sciences |
Intracranial Atherosclerotic Burden and Cerebral Parenchymal Changes at 7T MRI in Patients With Transient Ischemic Attack or Ischemic Stroke. | Lindenholz A, de Bresser J, van der Kolk AG, van der Worp HB, Witkamp TD, Hendrikse J, van der Schaaf IC | 2021-01-01 | intracranial arteries, intracranial atherosclerosis, intracranial vessel wall MR imaging, large vessel disease, small vessel disease, white matter hyperintensity | Frontiers in neurology |
Sex and Cardiovascular Function in Relation to Vascular Brain Injury in Patients with Cognitive Complaints. | Kuipers S, Biessels GJ, Greving JP, Amier RP, de Bresser J, Bron EE, van der Flier WM, van der Geest RJ, Hooghiemstra AM, van Oostenbrugge RJ, van Osch MJP, Kappelle LJ, Exalto LG | 2021-01-01 | Cardiovascular function, cerebrovascular disorders, cognitive dysfunction, female, male, sex, vascular brain injury | Journal of Alzheimer's disease : JAD |
Blood pressure, antihypertensive medication and neuropsychiatric symptoms in older people with dementia: The COSMOS study. | de Jong-Schmit BEM, Poortvliet RKE, Böhringer S, Bogaerts JMK, Achterberg WP, Husebo BS | 2021-01-01 | antihypertensive medication, blood pressure, dementia, neuropsychiatric symptoms | International journal of geriatric psychiatry |
Caffeine Consumption and Behavioral Symptoms in Nursing Home Residents: A Cross-Sectional Analysis. | Kromhout MA, Rius Ottenheim N, Putter H, Numans ME, Achterberg WP | 2021-01-01 | Behavioral symptoms, caffeine, dementia, nursing home | The journal of nutrition, health & aging |
Physicians’ perceived barriers and proposed solutions for high-quality palliative care in dementia in the Netherlands: Qualitative analysis of survey data. | Bavelaar L, van der Steen HTA, de Jong H, Carter G, Brazil K, Achterberg WP, van der Steen JT | 2021-01-01 | Dementia, geriatrics, nursing homes, palliative care | The journal of nursing home research sciences |
Caregiver dementia training in caregiver-patient dyads: Process evaluation of a randomized controlled study. | Birkenhäger-Gillesse EG, Achterberg WP, Janus SIM, Zuidema SU | 2021-01-01 | caregiver, dementia, psychosocial intervention, training | International journal of geriatric psychiatry |
Are Chronic Pain Patients with Dementia Being Undermedicated? | Achterberg WP, Erdal A, Husebo BS, Kunz M, Lautenbacher S | 2021-01-01 | analgesic treatment, assessment, dementia, pain | Journal of pain research |
Pan-European Study on Functional and Medical Recovery and Geriatric Rehabilitation Services of Post-COVID-19 Patients: Protocol of the EU-COGER Study. | Grund S, Caljouw MAA, Haaksma ML, Gordon AL, van Balen R, Bauer JM, Schols JMGA, Achterberg WP | 2021-01-01 | ADL functioning, COVID-19, geriatric rehabilitation, older persons, post-acute | The journal of nutrition, health & aging |
Effects of Caregiver Dementia Training in Caregiver-Patient Dyads on Psychotropic Drug Prescription: A Randomized Controlled Study. | Birkenhäger-Gillesse EG, Janus SIM, Achterberg WP, Zuidema SU | 2021-01-01 | caregiver, dementia, psychosocial intervention, psychotropic drugs, training | Clinical interventions in aging |
Does paracetamol improve quality of life, discomfort, pain and neuropsychiatric symptoms in persons with advanced dementia living in long-term care facilities? A randomised double-blind placebo-controlled crossover (Q-PID) trial. | van Dam PH, Achterberg WP, Husebo BS, Caljouw MAA | 2020-12-21 | Dementia, Long-term care facility, Paracetamol, QUALIDEM, Quality of life | BMC medicine |
Association of common genetic variants with brain microbleeds: A genome-wide association study. | Knol MJ, Lu D, Traylor M, Adams HHH, Romero JRJ, Smith AV, Fornage M, Hofer E, Liu J, Hostettler IC, Luciano M, Trompet S, Giese AK, Hilal S, van den Akker EB, Vojinovic D, Li S, Sigurdsson S, van der Lee SJ, Jack CR, Wilson D, Yilmaz P, Satizabal CL, Liewald DCM, van der Grond J, Chen C, Saba Y, van der Lugt A, Bastin ME, Windham BG, Cheng CY, Pirpamer L, Kantarci K, Himali JJ, Yang Q, Morris Z, Beiser AS, Tozer DJ, Vernooij MW, Amin N, Beekman M, Koh JY, Stott DJ, Houlden H, Schmidt R, Gottesman RF, MacKinnon AD, DeCarli C, Gudnason V, Deary IJ, van Duijn CM, Slagboom PE, Wong TY, Rost NS, Jukema JW, Mosley TH, Werring DJ, Schmidt H, Wardlaw JM, Ikram MA, Seshadri S, Launer LJ, Markus HS | 2020-12-15 | Neurology | |
Associations between Lifestyle Factors and Vitamin E Metabolites in the General Population. | Martens LG, Luo J, Meulmeester FL, Ashrafi N, van Eekelen EW, de Mutsert R, Mook-Kanamori DO, Rosendaal FR, van Dijk KW, Mills K, Noordam R, van Heemst D | 2020-12-15 | alcohol, antioxidants, diet, lifestyle, physical activity, sleep, smoking, vitamin E | Antioxidants (Basel, Switzerland) |
Introduction of Criterion-Based Audit of Postpartum Hemorrhage in a University Hospital in Eastern Ethiopia: Implementation and Considerations. | Tura AK, Aboul-Ela Y, Fage SG, Ahmed SS, Scherjon S, van Roosmalen J, Stekelenburg J, Zwart J, van den Akker T | 2020-12-11 | Ethiopia, criterion-based audit, postpartum hemorrhage | International journal of environmental research and public health |
Perspectives of health workers on the referral of women with obstetric complications: a qualitative study in rural Sierra Leone. | Proos R, Mathéron H, Vas Nunes J, Falama A, Sery Kamal P, Grobusch MP, van den Akker T | 2020-12-10 | maternal medicine, organisation of health services, public health, qualitative research | BMJ open |
Kawasaki disease seasonality in Venezuela supports an arbovirus infection trigger. | Paniz-Mondolfi AE, van den Akker T, Márquez-Colmenarez MC, Delgado-Noguera LA, Valderrama O, Sordillo EM | 2020-12-01 | DENV, Kawasaki disease, Venezuela, arboviruses, seasonality | Journal of medical virology |
Self-organizing peer coach groups to increase daily physical activity in community dwelling older adults. | van de Vijver P, Schalkwijk F, Numans ME, Slaets JPJ, van Bodegom D | 2020-12-01 | Feasibility, Implementation, Older adults, Peer coaching, Physical activity, Replicability | Preventive medicine reports |
Prediction admission in the older population in the Emergency Department: the CLEARED tool. | Brink A, Alsma J, Brink HS, de Gelder J, Lucke JA, Mooijaart SP, Zietse R, Schuit SCE, Lingsma HF | 2020-12-01 | The Netherlands journal of medicine | |
Measuring daily functioning in older persons using a frailty index: a cohort study based on routine primary care data. | Ravensbergen WM, Blom JW, Evers AW, Numans ME, de Waal MW, Gussekloo J | 2020-12-01 | activities of daily living, aged, electronic health records, frail older persons, general practice | The British journal of general practice : the journal of the Royal College of General Practitioners |
Experiences with the Liverpool care pathway for the dying patient in nursing home residents: a mixed-method study to assess physicians’ and nurse practitioners’ perceptions. | Klapwijk MS, Dekker NL, Caljouw MAA, Achterberg WP, van der Steen JT | 2020-11-30 | Dementia, End-of-life care, Liverpool care pathway, Nursing home, Palliative care, Quality of care | BMC palliative care |
Associations between outdoor temperature and bright sunlight with metabolites in two population-based European cohorts. | Eveleens Maarse BC, Loh NY, Karpe F, Rosendaal FR, van Heemst D, Mook-Kanamori DO, Willems van Dijk K, Rensen PCN, Kooijman S, Christodoulides C, Noordam R | 2020-11-27 | Cohort studies, Epidemiology, Lipoproteins, Metabolomics, Outdoor bright sunlight, Outdoor temperature | Nutrition, metabolism, and cardiovascular diseases : NMCD |
A Workflow for Missing Values Imputation of Untargeted Metabolomics Data. | Faquih T, van Smeden M, Luo J, le Cessie S, Kastenmüller G, Krumsiek J, Noordam R, van Heemst D, Rosendaal FR, van Hylckama Vlieg A, Willems van Dijk K, Mook-Kanamori DO | 2020-11-26 | imputation, k-nearest neighbors, metabolon, multiple imputation using chained equations, simulation, untargeted metabolomics, workflow | Metabolites |
Which moral barriers and facilitators do physicians encounter in advance care planning conversations about the end of life of persons with dementia? A meta-review of systematic reviews and primary studies. | Keijzer-van Laarhoven AJ, Touwen DP, Tilburgs B, van Tilborg-den Boeft M, Pees C, Achterberg WP, van der Steen JT | 2020-11-12 | geriatric medicine, medical ethics, palliative care, primary care | BMJ open |
Impact of Medical Doctors Global Health and Tropical Medicine on decision-making in caesarean section: a pre- and post-implementation study in a rural hospital in Malawi. | Bakker W, Bakker E, Huigens C, Kaunda E, Phiri T, Beltman J, van Roosmalen J, van den Akker T | 2020-11-09 | Associate clinicians, Audit, Caesarean section, MDGHTM, Unnecessary caesareans | Human resources for health |
An individual participant data analysis of prospective cohort studies on the association between subclinical thyroid dysfunction and depressive symptoms. | Wildisen L, Del Giovane C, Moutzouri E, Beglinger S, Syrogiannouli L, Collet TH, Cappola AR, Åsvold BO, Bakker SJL, Yeap BB, Almeida OP, Ceresini G, Dullaart RPF, Ferrucci L, Grabe H, Jukema JW, Nauck M, Trompet S, Völzke H, Westendorp R, Gussekloo J, Klöppel S, Aujesky D, Bauer D, Peeters R, Feller M, Rodondi N | 2020-11-05 | Scientific reports | |
Effects of caregiver dementia training in caregiver-patient dyads: A randomized controlled study. | Birkenhäger-Gillesse EG, Achterberg WP, Janus SIM, Kollen BJ, Zuidema SU | 2020-11-01 | caregiver, dementia, psychosocial intervention, training | International journal of geriatric psychiatry |
What do older adults with multimorbidity and polypharmacy think about deprescribing? The LESS study – a primary care-based survey. | Rozsnyai Z, Jungo KT, Reeve E, Poortvliet RKE, Rodondi N, Gussekloo J, Streit S | 2020-10-31 | Deprescribing, General practice, Multimorbidity, Older adults, Patient attitudes, Polypharmacy | BMC geriatrics |
Feasibility and acceptability of the ‘Acutely Presenting Older Patient’ screener in routine emergency department care. | Blomaard LC, Mooijaart SP, Bolt S, Lucke JA, de Gelder J, Booijen AM, Gussekloo J, de Groot B | 2020-10-23 | emergency department, feasibility studies, geriatric assessment, geriatric emergency medicine, implementation science, older people | Age and ageing |
Older individuals’ views on their personal screening results for complex health problems: a qualitative study. | van Blijswijk SCE, van Tol LS, Blom JW, den Elzen WPJ, Gussekloo J | 2020-10-19 | Community-dwelling older persons, Older individuals’ views, Personal goals, Screening questionnaire, Self-management | BMC family practice |
Circulating Thyroid Hormone Profile in Response to a Triiodothyronine Challenge in Familial Longevity. | Zutinic A, Blauw GJ, Pijl H, Ballieux BE, Westendorp RGJ, Roelfsema F, van Heemst D | 2020-10-01 | 3, 5, 3′-triiodothyronine, TSH, longevity, negative feedback, thyroid | Journal of the Endocrine Society |
Epidemiological analysis of peripartum hysterectomy across nine European countries. | Kallianidis AF, Maraschini A, Danis J, Colmorn LB, Deneux-Tharaux C, Donati S, Gissler M, Jakobsson M, Knight M, Kristufkova A, Lindqvist PG, Vandenberghe G, Van Den Akker T | 2020-10-01 | cesarean section, maternal morbidity, mode of birth, obstetric hemorrhage, peripartum hysterectomy | Acta obstetricia et gynecologica Scandinavica |
Impact of COVID-19 on maternal and child health. | Dmello BS, Housseine N, van den Akker T, van Roosmalen J, Maaløe N | 2020-10-01 | The Lancet. Global health | |
Metabolic Age Based on the BBMRI-NL 1H-NMR Metabolomics Repository as Biomarker of Age-related Disease. | van den Akker EB, Trompet S, Barkey Wolf JJH, Beekman M, Suchiman HED, Deelen J, Asselbergs FW, Boersma E, Cats D, Elders PM, Geleijnse JM, Ikram MA, Kloppenburg M, Mei H, Meulenbelt I, Mooijaart SP, Nelissen RGHH, Netea MG, Penninx BWJH, Slofstra M, Stehouwer CDA, Swertz MA, Teunissen CE, Terwindt GM, 't Hart LM, van den Maagdenberg AMJM, van der Harst P, van der Horst ICC, van der Kallen CJH, van Greevenbroek MMJ, van Spil WE, Wijmenga C, Zhernakova A, Zwinderman AH, Sattar N, Jukema JW, van Duijn CM, Boomsma DI, Reinders MJT, Slagboom PE | 2020-10-01 | aging, cardiovascular disease, data science, metabolomics | Circulation. Genomic and precision medicine |
ExploreASL: An image processing pipeline for multi-center ASL perfusion MRI studies. | Mutsaerts HJMM, Petr J, Groot P, Vandemaele P, Ingala S, Robertson AD, Václavů L, Groote I, Kuijf H, Zelaya F, O'Daly O, Hilal S, Wink AM, Kant I, Caan MWA, Morgan C, de Bresser J, Lysvik E, Schrantee A, Bjørnebekk A, Clement P, Shirzadi Z, Kuijer JPA, Wottschel V, Anazodo UC, Pajkrt D, Richard E, Bokkers RPH, Reneman L, Masellis M, Günther M, MacIntosh BJ, Achten E, Chappell MA, van Osch MJP, Golay X, Thomas DL, De Vita E, Bjørnerud A, Nederveen A, Hendrikse J, Asllani I, Barkhof F | 2020-10-01 | Arterial spin labeling, Cerebral perfusion, Image processing, Multi-center, Quality control | NeuroImage |
Myelin water imaging from multi-echo T2 MR relaxometry data using a joint sparsity constraint. | Nagtegaal M, Koken P, Amthor T, de Bresser J, Mädler B, Vos F, Doneva M | 2020-10-01 | Demyelination, Joint sparsity constraint, Myelin water fraction, T(2) relaxometry | NeuroImage |
Crying out in pain-A systematic review into the validity of vocalization as an indicator for pain. | Helmer LML, Weijenberg RAF, de Vries R, Achterberg WP, Lautenbacher S, Sampson EL, Lobbezoo F | 2020-10-01 | European journal of pain (London, England) | |
Independent factors associated with long-term functional outcomes in patients with a proximal femoral fracture: A systematic review. | van der Sijp MPL, van Eijk M, Tong WH, Niggebrugge AHP, Schoones JW, Blauw GJ, Achterberg WP | 2020-10-01 | Function, Functional outcome, Hip fracture, Long-term, Prognostic factors, Proximal femoral fracture | Experimental gerontology |
Metabolic Age Based on the BBMRI-NL 1H-NMR Metabolomics Repository as Biomarker of Age-related Disease | van den Akker EB, Trompet S, Barkey Wolf JJ, Beekman M, Suchiman HED, Deelen J, Asselbergs FW, Boersma E, Cats D, Elders PM, Geleijnse JM, Ikram MA, Kloppenburg M, Mei H, Meulenbelt I, Mooijaart SP, Nelissen RG, Netea MG, Penninx BW, Slofstra M, Stehouwer CD, Swertz MA, Teunissen CE, Terwindt GM, ‘t Hart LM, van den Maagdenberg AM, van der Harst P, van der Horst IC, van der Kallen CJ, van Greevenbroek MM, van Spil WE, Wijmenga C, Zhernakova A, Zwinderman AH, Sattar N, Jukema JW, van Duijn CM, Boomsma DI, Reinders MJ, Slagboom PE | 2020-10-01 | Genomic and Precision Medicine | |
Serum fatty acid chain length associates with prevalent symptomatic end-stage osteoarthritis, independent of BMI. | Meessen JMTA, Saberi-Hosnijeh F, Bomer N, den Hollander W, van der Bom JG, van Hilten JA, van Spil WE, So-Osman C, Uitterlinden AG, Kloppenburg M, Nelissen RGHH, van Duijn CM, Slagboom PE, van Meurs JBJ, Meulenbelt I | 2020-09-22 | Scientific reports | |
Effect of Thyroid Hormone Therapy on Fatigability in Older Adults With Subclinical Hypothyroidism: A Nested Study Within a Randomized Placebo-Controlled Trial. | Stuber MJ, Moutzouri E, Feller M, Del Giovane C, Bauer DC, Blum MR, Collet TH, Gussekloo J, Mooijaart SP, McCarthy VJC, Aujesky D, Westendorp R, Stott DJ, Glynn NW, Kearney PM, Rodondi N | 2020-09-16 | Fatigue, Levothyroxine, Thyroid disease | The journals of gerontology. Series A, Biological sciences and medical sciences |
Refining Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder Genetic Loci by Integrating Summary Data From Genome-wide Association, Gene Expression, and DNA Methylation Studies. | Hammerschlag AR, Byrne EM, Bartels M, Wray NR, Middeldorp CM | 2020-09-15 | Fetal brain, Pleiotropy, Psychiatric disorders, SMR, eQTL, mQTL | Biological psychiatry |
Cost-effectiveness of the Namaste care family program for nursing home residents with advanced dementia in comparison with usual care: a cluster-randomized controlled trial. | El Alili M, Smaling HJA, Joling KJ, Achterberg WP, Francke AL, Bosmans JE, van der Steen JT | 2020-09-04 | Cluster randomized controlled trial, Cost-benefit analysis, Dementia, Family caregiving, Namaste care, Nursing home, Palliative care, Person-centered care, Quality of life | BMC health services research |
Activation of cytotoxic T cell population and inversion of CD4:CD8 ratio as manifestations of cellular immune response in SARS-COV-2 infection. | Khan F, van den Akker T, Hussein S, Marcellino BK, Khattar P, Glicksberg BS, Nadkarni GN, Firpo-Betancourt A, El Jamal SM | 2020-09-01 | Journal of hematopathology | |
Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference. | Hop PJ, Luijk R, Daxinger L, van Iterson M, Dekkers KF, Jansen R, van Meurs JBJ, 't Hoen PAC, Ikram MA, van Greevenbroek MMJ, Boomsma DI, Slagboom PE, Veldink JH, van Zwet EW, Heijmans BT | 2020-08-28 | Causal inference, Chromatin, DNA methylation, Epigenetic regulation, Functional genomics, Genetic instrumental variable, Pleiotropy, Transcription factor | Genome biology |
Proteome-wide assessment of diabetes mellitus in Qatari identifies IGFBP-2 as a risk factor already with early glycaemic disturbances. | Noordam R, van Heemst D, Suhre K, Krumsiek J, Mook-Kanamori DO | 2020-08-15 | Case-control study, Diabetes mellitus, Mendelian randomization, Metabolomics, Proteomics | Archives of biochemistry and biophysics |
The contribution of tissue-grouped BMI-associated gene sets to cardiometabolic-disease risk: a Mendelian randomization study. | Verkouter I, de Mutsert R, Smit RAJ, Trompet S, Rosendaal FR, van Heemst D, Willems van Dijk K, Noordam R | 2020-08-01 | Mendelian randomization analysis, anthropometry, body mass index, coronary artery disease, type 2 diabetes mellitus, waist circumference | International journal of epidemiology |
Genome-Wide Association Study of the Postprandial Triglyceride Response Yields Common Genetic Variation in LIPC (Hepatic Lipase). | Ibi D, Noordam R, van Klinken JB, Li-Gao R, de Mutsert R, Trompet S, Christen T, Blauw LL, van Heemst D, Mook-Kanamori DO, Rosendaal FR, Jukema JW, Dollé MET, Rensen PCN, van Dijk KW | 2020-08-01 | Genome-wide association studies, cardiovascular diseases, hepatic lipase, lipoprotein metabolism, metabolites, postprandial triglyceride response | Circulation. Genomic and precision medicine |
Maternal near-miss surveillance, Namibia. | Heemelaar S, Josef M, Diener Z, Chipeio M, Stekelenburg J, van den Akker T, Mackenzie S | 2020-08-01 | Bulletin of the World Health Organization | |
Geriatric Screening, Triage Urgency, and 30-Day Mortality in Older Emergency Department Patients. | Blomaard LC, Speksnijder C, Lucke JA, de Gelder J, Anten S, Schuit SCE, Steyerberg EW, Gussekloo J, de Groot B, Mooijaart SP | 2020-08-01 | emergency department, geriatric assessment, geriatric emergency medicine, risk stratification, triage | Journal of the American Geriatrics Society |
The role of C-reactive protein, adiponectin and leptin in the association between abdominal adiposity and insulin resistance in middle-aged individuals. | Noordam R, Boersma V, Verkouter I, le Cessie S, Christen T, Lamb HJ, Rosendaal FR, Willems van Dijk K, van Heemst D, de Mutsert R | 2020-07-24 | Abdominal obesity, Adipokines, Epidemiology, Inflammation, Insulin resistance | Nutrition, metabolism, and cardiovascular diseases : NMCD |
Socioeconomic differences in caesarean section – are they explained by medical need? An analysis of patient record data of a large Kenyan hospital. | van der Spek L, Sanglier S, Mabeya HM, van den Akker T, Mertens PLJM, Houweling TAJ | 2020-07-08 | Africa, Caesarean section, Clinical category, Delivery, Developing countries, Epidemiology, General obstetric, General obstetrics, Health equity, Maternity services, Obstetrics and gynaecology, Pregnancy, Socioeconomic factors | International journal for equity in health |
Familial Longevity is Associated with an Attenuated Thyroidal Response to Recombinant Human Thyroid Stimulating Hormone. | Zutinic A, Pijl H, Ballieux BE, Roelfsema F, Westendorp RGJ, Blauw GJ, van Heemst D | 2020-07-01 | Thyroid, longevity, recombinant human TSH, responsivity | The Journal of clinical endocrinology and metabolism |
Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood. | Zheng Y, Huang T, Wang T, Mei Z, Sun Z, Zhang T, Ellervik C, Chai JF, Sim X, van Dam RM, Tai ES, Koh WP, Dorajoo R, Saw SM, Sabanayagam C, Wong TY, Gupta P, Rossing P, Ahluwalia TS, Vinding RK, Bisgaard H, Bønnelykke K, Wang Y, Graff M, Voortman T, van Rooij FJA, Hofman A, van Heemst D, Noordam R, Estampador AC, Varga TV, Enzenbach C, Scholz M, Thiery J, Burkhardt R, Orho-Melander M, Schulz CA, Ericson U, Sonestedt E, Kubo M, Akiyama M, Zhou A, Kilpeläinen TO, Hansen T, Kleber ME, Delgado G, McCarthy M, Lemaitre RN, Felix JF, Jaddoe VWV, Wu Y, Mohlke KL, Lehtimäki T, Wang CA, Pennell CE, Schunkert H, Kessler T, Zeng L, Willenborg C, Peters A, Lieb W, Grote V, Rzehak P, Koletzko B, Erdmann J, Munz M, Wu T, He M, Yu C, Lecoeur C, Froguel P, Corella D, Moreno LA, Lai CQ, Pitkänen N, Boreham CA, Ridker PM, Rosendaal FR, de Mutsert R, Power C, Paternoster L, Sørensen TIA, Tjønneland A, Overvad K, Djousse L, Rivadeneira F, Lee NR, Raitakari OT, Kähönen M, Viikari J, Langhendries JP, Escribano J, Verduci E, Dedoussis G, König I, Balkau B, Coltell O, Dallongeville J, Meirhaeghe A, Amouyel P, Gottrand F, Pahkala K, Niinikoski H, Hyppönen E, März W, Mackey DA, Gruszfeld D, Tucker KL, Fumeron F, Estruch R, Ordovas JM, Arnett DK, Mook-Kanamori DO, Mozaffarian D, Psaty BM, North KE, Chasman DI, Qi L | 2020-07-01 | Birthweight, Blood pressure, Causal association, Hypertension, Mendelian randomization | European journal of epidemiology |
Geriatric Screeners 2.0: Time for a Paradigm Shift in Emergency Department Vulnerability Research. | Carpenter CR, Mooijaart SP | 2020-07-01 | Journal of the American Geriatrics Society | |
The Impact of Levothyroxine on Cardiac Function in Older Adults With Mild Subclinical Hypothyroidism: A Randomized Clinical Trial. | Gencer B, Moutzouri E, Blum MR, Feller M, Collet TH, Delgiovane C, da Costa BR, Buffle E, Monney P, Gabus V, Müller H, Sykiotis GP, Kearney P, Gussekloo J, Westendorp R, Stott DJ, Bauer DC, Rodondi N | 2020-07-01 | Clinical trials, Heart failure, Levothyroxine, Subclinical hypothyroidism, Thyroid | The American journal of medicine |
Cerebral cortical microinfarcts: A novel MRI marker of vascular brain injury in patients with heart failure. | Ferro D, van den Brink H, Amier R, van Buchem M, de Bresser J, Bron E, Brunner-La Rocca HP, Hooghiemstra A, Marcks N, van Rossum A, Biessels GJ | 2020-07-01 | Atherosclerosis, Cerebrovascular disease/stroke, Cognitive impairment, Embolism, Heart failure | International journal of cardiology |
Impact of visuospatial neglect post-stroke on daily activities, participation and informal caregiver burden: A systematic review. | Bosma MS, Nijboer TCW, Caljouw MAA, Achterberg WP | 2020-07-01 | Activities of daily living, Caregiver burden, Participation, Stroke, Unilateral neglect, Visuospatial neglect | Annals of physical and rehabilitation medicine |
Beyond No Blame: Practical Challenges of Conducting Maternal and Perinatal Death Reviews in Eastern Ethiopia. | Tura AK, Fage SG, Ibrahim AM, Mohamed A, Ahmed R, Gure T, Zwart J, van den Akker T | 2020-06-30 | Global health, science and practice | |
Biomarkers versus traditional risk factors to predict cardiovascular events in very old adults: cross-validated prospective cohort study. | Vaes B, Indestege P, Serneels T, Hegendörfer E, van Peet PG, Poortvliet RKE, Wallemacq P, Gussekloo J, Degryse J | 2020-06-28 | cardiac epidemiology, epidemiology, geriatric medicine | BMJ open |
L-Thyroxine Therapy for Older Adults With Subclinical Hypothyroidism and Hypothyroid Symptoms: Secondary Analysis of a Randomized Trial. | de Montmollin M, Feller M, Beglinger S, McConnachie A, Aujesky D, Collet TH, Ford I, Gussekloo J, Kearney PM, McCarthy VJC, Mooijaart S, Poortvliet RKE, Quinn T, Stott DJ, Watt T, Westendorp R, Rodondi N, Bauer DC | 2020-06-02 | Annals of internal medicine | |
Information needs of older patients living with chronic obstructive pulmonary disease (COPD) indicated for a specific geriatric rehabilitation programme: a prospective cohort study. | Wouters TJ, van Dam van Isselt EF, Achterberg WP | 2020-06-02 | Advanced COPD, Geriatric rehabilitation, Health status, Pulmonary rehabilitation, Self-management | International journal of palliative nursing |
Longevity Relatives Count score identifies heritable longevity carriers and suggests case improvement in genetic studies. | van den Berg N, Rodríguez-Girondo M, Mandemakers K, Janssens AAPO, Beekman M, Slagboom PE | 2020-06-01 | aging, family tree, genetics, inheritance, longevity | Aging cell |
Genetics and Not Shared Environment Explains Familial Resemblance in Adult Metabolomics Data. | Pool R, Hagenbeek FA, Hendriks AM, van Dongen J, Willemsen G, de Geus E, Willems van Dijk K, Verhoeven A, Suchiman HE, Beekman M, Slagboom PE, Harms AC, Hankemeier T, Boomsma DI | 2020-06-01 | Classical twin design, enrichment analysis, heritability, metabolite classes, shared environment | Twin research and human genetics : the official journal of the International Society for Twin Studies |
Maternal mortality due to cardiac disease in low- and middle-income countries. | Heemelaar S, Petrus A, Knight M, van den Akker T | 2020-06-01 | cardiac disease, low- and middle-income countries, maladie cardiaque, maternal mortality, mortalité maternelle, pays à revenu faible ou intermédiaire | Tropical medicine & international health : TM & IH |
Surviving mothers and lost babies – burden of stillbirths and neonatal deaths among women with maternal near miss in eastern Ethiopia: a prospective cohort study. | Tura AK, Scherjon S, van Roosmalen J, Zwart J, Stekelenburg J, van den Akker T | 2020-06-01 | Journal of global health | |
Voices from the frontline: findings from a thematic analysis of a rapid online global survey of maternal and newborn health professionals facing the COVID-19 pandemic. | Semaan A, Audet C, Huysmans E, Afolabi B, Assarag B, Banke-Thomas A, Blencowe H, Caluwaerts S, Campbell OMR, Cavallaro FL, Chavane L, Day LT, Delamou A, Delvaux T, Graham WJ, Gon G, Kascak P, Matsui M, Moxon S, Nakimuli A, Pembe A, Radovich E, van den Akker T, Benova L | 2020-06-01 | child health, cross-sectional survey, health services research, health systems, maternal health | BMJ global health |
The Challenges of Managing Inflammatory Bowel Diseases in Older Patients. | Asscher VER, E van der Meulen-de Jong A, Mooijaart SP | 2020-06-01 | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association | |
Lifestyle-Intervention-Induced Reduction of Abdominal Fat Is Reflected by a Decreased Circulating Glycerol Level and an Increased HDL Diameter. | Beekman M, Schutte BAM, Akker EBVD, Noordam R, Dibbets-Schneider P, de Geus-Oei LF, Deelen J, Rest OV, Heemst DV, Feskens EJM, Slagboom PE | 2020-05-01 | abdominal fat, biomarkers, lifestyle interventions, metabolomics | Molecular nutrition & food research |
Evaluation of mode of birth in pregnant women with heart disease. | Petrus AHJ, Jongert BL, Kiès P, Sueters M, Jongbloed MRM, Vliegen HW, Schalij MJ, van Lith J, van den Akker T | 2020-05-01 | Heart disease, Mode of birth, Pregnancy, Pregnancy outcomes | European journal of obstetrics, gynecology, and reproductive biology |
Frequency and management of maternal infection in health facilities in 52 countries (GLOSS): a 1-week inception cohort study. | 2020-05-01 | The Lancet. Global health | ||
Variations in use of childbirth interventions in 13 high-income countries: A multinational cross-sectional study. | Seijmonsbergen-Schermers AE, van den Akker T, Rydahl E, Beeckman K, Bogaerts A, Binfa L, Frith L, Gross MM, Misselwitz B, Hálfdánsdóttir B, Daly D, Corcoran P, Calleja-Agius J, Calleja N, Gatt M, Vika Nilsen AB, Declercq E, Gissler M, Heino A, Lindgren H, de Jonge A | 2020-05-01 | PLoS medicine | |
Effectiveness of intramuscular gluteal glucocorticoid injection versus intra-articular glucocorticoid injection in knee osteoarthritis: design of a multicenter randomized, 24 weeks comparative parallel-group trial. | Mol MF, Runhaar J, Bos PK, Dorleijn DMJ, Vis M, Gussekloo J, Bindels PJE, Bierma-Zeinstra SMA | 2020-04-11 | General practice, Glucocorticoid injection, Intra-articular, Intramuscular, Knee osteoarthritis, Non-inferiority, Primary care, Randomized controlled trial | BMC musculoskeletal disorders |
Patterns and characteristics of cognitive functioning in older patients approaching end stage kidney disease, the COPE-study. | van Deudekom FJ, Kallenberg MH, Berkhout-Byrne NC, Blauw GJ, Boom H, de Bresser J, van Buchem MA, Gaasbeek A, Hammer S, Lagro J, van Osch MJP, Witjes-Ané MN, Rabelink TJ, van Buren M, Mooijaart SP | 2020-04-09 | Cognitive function, End stage renal disease, Geriatric assessment, Geriatrics, Older patients | BMC nephrology |
Association of handgrip strength with patient-reported outcome measures after total hip and knee arthroplasty. | Meessen JMTA, Fiocco M, Tordoir RL, Sjer A, Verdegaal SHM, Slagboom PE, Vliet Vlieland TPM, Nelissen RGHH | 2020-04-01 | Handgrip strength (HGS), Osteoarthritis (OA), Rehabilitation, Total hip arthroplasty (THA), Total knee arthroplasty (TKA) | Rheumatology international |
A data-driven methodology reveals novel myofiber clusters in older human muscles. | Raz Y, van den Akker EB, Roest T, Riaz M, van de Rest O, Suchiman HED, Lakenberg N, Stassen SA, van Putten M, Feskens EJM, Reinders MJT, Goeman J, Beekman M, Raz V, Slagboom PE | 2020-04-01 | RNA-sequencing, bioinformatics, clustering, fibertyping, human, muscle, muscle health, myofiber, myosin heavy chain, sarcomere | FASEB journal : official publication of the Federation of American Societies for Experimental Biology |
Repeat UVA exposure of human skin fibroblasts induces both a transitionary and recovery DNA methylation response. | Tilburg J, Slieker RC, Suchiman HED, Heath A, Heemst DV, Slagboom PE, de Gruijl FR, Gunn DA, Heijmans BT | 2020-04-01 | UVA irradiation, dermis, fibroblasts, genome-wide DNA methylation, photoaging, skin aging | Epigenomics |
Interrelationships Between Pituitary Hormones as Assessed From 24-hour Serum Concentrations in Healthy Older Subjects. | van der Spoel E, Roelfsema F, Akintola AA, Jansen SW, Slagboom PE, Westendorp RGJ, Blauw GJ, Pijl H, van Heemst D | 2020-04-01 | cross-approximate entropy, cross-correlation, familial longevity, human, pituitary hormones, time series data | The Journal of clinical endocrinology and metabolism |
Effect of Fixed-Density Thresholding on Structural Brain Networks: A Demonstration in Cerebral Small Vessel Disease. | de Brito Robalo BM, Vlegels N, Meier J, Leemans A, Biessels GJ, Reijmer YD | 2020-04-01 | brain connectivity, cerebral small vessel disease, diffusion tensor imaging, network density, network thresholding | Brain connectivity |
European consensus on core principles and future priorities for geriatric rehabilitation: consensus statement. | Grund S, Gordon AL, van Balen R, Bachmann S, Cherubini A, Landi F, Stuck AE, Becker C, Achterberg WP, Bauer JM, Schols JMGA | 2020-04-01 | EuGMS, European consensus, Frailty, Functional decline, Geriatric rehabilitation | European geriatric medicine |
Author Correction: Heritability estimates for 361 blood metabolites across 40 genome-wide association studies. | Hagenbeek FA, Pool R, van Dongen J, Draisma HM, Jan Hottenga J, Willemsen G, Abdellaoui A, Fedko IO, den Braber A, Visser PJ, de Geus EJCN, Willems van Dijk K, Verhoeven A, Suchiman HE, Beekman M, Slagboom PE, van Duijn CM, Harms AC, Hankemeier T, Bartels M, Nivard MG, Boomsma DI | 2020-03-31 | Nature communications | |
The modified functional comorbidity index performed better than the Charlson index and original functional comorbidity index in predicting functional outcome in geriatric rehabilitation: a prospective observational study. | Kabboord AD, Godfrey D, Gordon AL, Gladman JRF, Van Eijk M, van Balen R, Achterberg WP | 2020-03-29 | BMC geriatrics | |
Ventricular Repolarization is Associated with Cognitive Function, but Not with Cognitive Decline and Brain Magnetic Resonance Imaging (MRI) Measurements in Older Adults. | Zonneveld MH, Noordam R, Grond JV, Sabayan B, Mooijaart SP, Mcfarlane PW, Jukema JW, Trompet S | 2020-03-26 | MRI, cardiovascular disease, cognitive dysfunction, older adults, prolonged QT interval | Journal of clinical medicine |
Treatment of Older Adults With Subclinical Hypothyroidism-Reply. | Mooijaart SP, Du Puy RS | 2020-03-17 | JAMA | |
Arterial CO2 pressure changes during hypercapnia are associated with changes in brain parenchymal volume. | van der Kleij LA, De Vis JB, de Bresser J, Hendrikse J, Siero JCW | 2020-03-09 | Brain, Cerebral blood volume, Healthy volunteers, Hypercapnia, Intracranial pressure, Magnetic resonance imaging | European radiology experimental |
Genome-wide analysis of constitutional DNA methylation in familial melanoma. | Salgado C, Gruis N, Heijmans BT, Oosting J, van Doorn R | 2020-03-06 | DNA methylation, Epimutation, Familial melanoma, Loss of imprinting | Clinical epigenetics |
Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. | Li C, Stoma S, Lotta LA, Warner S, Albrecht E, Allione A, Arp PP, Broer L, Buxton JL, Da Silva Couto Alves A, Deelen J, Fedko IO, Gordon SD, Jiang T, Karlsson R, Kerrison N, Loe TK, Mangino M, Milaneschi Y, Miraglio B, Pervjakova N, Russo A, Surakka I, van der Spek A, Verhoeven JE, Amin N, Beekman M, Blakemore AI, Canzian F, Hamby SE, Hottenga JJ, Jones PD, Jousilahti P, Mägi R, Medland SE, Montgomery GW, Nyholt DR, Perola M, Pietiläinen KH, Salomaa V, Sillanpää E, Suchiman HE, van Heemst D, Willemsen G, Agudo A, Boeing H, Boomsma DI, Chirlaque MD, Fagherazzi G, Ferrari P, Franks P, Gieger C, Eriksson JG, Gunter M, Hägg S, Hovatta I, Imaz L, Kaprio J, Kaaks R, Key T, Krogh V, Martin NG, Melander O, Metspalu A, Moreno C, Onland-Moret NC, Nilsson P, Ong KK, Overvad K, Palli D, Panico S, Pedersen NL, Penninx BWJH, Quirós JR, Jarvelin MR, Rodríguez-Barranco M, Scott RA, Severi G, Slagboom PE, Spector TD, Tjonneland A, Trichopoulou A, Tumino R, Uitterlinden AG, van der Schouw YT, van Duijn CM, Weiderpass E, Denchi EL, Matullo G, Butterworth AS, Danesh J, Samani NJ, Wareham NJ, Nelson CP, Langenberg C, Codd V | 2020-03-05 | Mendelian randomisation, age-related disease, biological aging, telomere length | American journal of human genetics |
The association of kidney function and cognitive decline in older patients at risk of cardiovascular disease: a longitudinal data analysis. | Zijlstra LE, Trompet S, Mooijaart SP, van Buren M, Sattar N, Stott DJ, Jukema JW | 2020-03-05 | Chronic kidney disease, Cognitive function, Vascular disease | BMC nephrology |
Metabolomics analyses in non-diabetic middle-aged individuals reveal metabolites impacting early glucose disturbances and insulin sensitivity. | Bos MM, Noordam R, Bennett K, Beekman M, Mook-Kanamori DO, Willems van Dijk K, Slagboom PE, Lundstedt T, Surowiec I, van Heemst D | 2020-03-02 | Glucose metabolism, Insulin sensitivity, Metabolomics, Type 2 diabetes mellitus | Metabolomics : Official journal of the Metabolomic Society |
Metabolomics Profile in Depression: A Pooled Analysis of 230 Metabolic Markers in 5283 Cases With Depression and 10,145 Controls. | Bot M, Milaneschi Y, Al-Shehri T, Amin N, Garmaeva S, Onderwater GLJ, Pool R, Thesing CS, Vijfhuizen LS, Vogelzangs N, Arts ICW, Demirkan A, van Duijn C, van Greevenbroek M, van der Kallen CJH, Köhler S, Ligthart L, van den Maagdenberg AMJM, Mook-Kanamori DO, de Mutsert R, Tiemeier H, Schram MT, Stehouwer CDA, Terwindt GM, Willems van Dijk K, Fu J, Zhernakova A, Beekman M, Slagboom PE, Boomsma DI, Penninx BWJH | 2020-03-01 | Biomarkers, Cardiovascular, Depression, Metabolites, Metabolomics, Pooled analysis | Biological psychiatry |
Predictive value of traditional risk factors for cardiovascular disease in older people: A systematic review. | van Bussel EF, Hoevenaar-Blom MP, Poortvliet RKE, Gussekloo J, van Dalen JW, van Gool WA, Richard E, Moll van Charante EP | 2020-03-01 | Cardiovascular disease, Older people, Prediction, Reversed epidemiology, Systematic review, Traditional risk factors | Preventive medicine |
A characterization of cis- and trans-heritability of RNA-Seq-based gene expression. | Ouwens KG, Jansen R, Nivard MG, van Dongen J, Frieser MJ, Hottenga JJ, Arindrarto W, Claringbould A, van Iterson M, Mei H, Franke L, Heijmans BT, A C 't Hoen P, van Meurs J, Brooks AI, Penninx BWJH, Boomsma DI | 2020-02-01 | European journal of human genetics : EJHG | |
Bone marrow morphologic features, MyPRS, and gene mutation correlations in plasma cell myeloma. | Hao Y, Khaykin D, Machado L, van den Akker T, Houldsworth J, Barlogie B, Hussein S, El Jamal SM, Petersen B, Teruya-Feldstein J | 2020-02-01 | Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc | |
Physiological-based cord clamping in very preterm infants – Randomised controlled trial on effectiveness of stabilisation. | Knol R, Brouwer E, van den Akker T, DeKoninck P, van Geloven N, Polglase GR, Lopriore E, Herkert E, Reiss IKM, Hooper SB, Te Pas AB | 2020-02-01 | Resuscitation | |
The APOP screener and clinical outcomes in older hospitalised internal medicine patients. | Blomaard LC, Lucke JA, de Gelder J, Anten S, Alsma J, Schuit SCE, Gussekloo J, de Groot B, Mooijaart SP | 2020-02-01 | The Netherlands journal of medicine | |
MRI phenotypes of the brain are related to future stroke and mortality in patients with manifest arterial disease: The SMART-MR study. | Jaarsma-Coes MG, Ghaznawi R, Hendrikse J, Slump C, Witkamp TD, van der Graaf Y, Geerlings MI, de Bresser J | 2020-02-01 | Brain imaging, atherosclerosis, cluster analysis, magnetic resonance imaging, patient outcome | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism |
Observational pain assessment in older persons with dementia in four countries: Observer agreement of items and factor structure of the Pain Assessment in Impaired Cognition. | de Waal MWM, van Dalen-Kok AH, de Vet HCW, Gimenez-Llort L, Konstantinovic L, de Tommaso M, Fischer T, Lukas A, Kunz M, Lautenbacher S, Lobbezoo F, McGuire BE, van der Steen JT, Achterberg WP | 2020-02-01 | European journal of pain (London, England) | |
Recommendations for (Discontinuation of) Statin Treatment in Older Adults: Review of Guidelines. | van der Ploeg MA, Floriani C, Achterberg WP, Bogaerts JMK, Gussekloo J, Mooijaart SP, Streit S, Poortvliet RKE, Drewes YM | 2020-02-01 | cardiovascular diseases, clinical decision making, drug therapy, hydroxymethylglutaryl-CoA reductase inhibitors, prevention | Journal of the American Geriatrics Society |
Heritability estimates for 361 blood metabolites across 40 genome-wide association studies. | Hagenbeek FA, Pool R, van Dongen J, Draisma HHM, Jan Hottenga J, Willemsen G, Abdellaoui A, Fedko IO, den Braber A, Visser PJ, de Geus EJCN, Willems van Dijk K, Verhoeven A, Suchiman HE, Beekman M, Slagboom PE, van Duijn CM, Harms AC, Hankemeier T, Bartels M, Nivard MG, Boomsma DI | 2020-01-07 | Nature communications | |
Association Between Blood Pressure Variability and Cerebral Small-Vessel Disease: A Systematic Review and Meta-Analysis. | Tully PJ, Yano Y, Launer LJ, Kario K, Nagai M, Mooijaart SP, Claassen JAHR, Lattanzi S, Vincent AD, Tzourio C | 2020-01-07 | blood pressure measurement/monitoring, blood pressure variability, high blood pressure, meta‐analysis, systematic review, white matter disease | Journal of the American Heart Association |
Association of cardiovascular structure and function with cerebrovascular changes and cognitive function in older patients with end-stage renal disease. | Zijlstra LE, Trompet S, Jukema JW, Kroft LJM, de Bresser J, van Osch MJP, Hammer S, Witjes MN, van Buren M, Mooijaart SP | 2020-01-07 | arterial stiffness, cerebrovascular changes, dementia, end stage renal disease, systolic heart function | Aging |
Major obstetric haemorrhage in Metro East, Cape Town, South Africa: a population-based cohort study using the maternal near-miss approach. | Heitkamp A, Aronson SL, van den Akker T, Vollmer L, Gebhardt S, van Roosmalen J, de Vries JI, Theron G | 2020-01-06 | Caesarean section, Major obstetric haemorrhage, Maternal near-miss, Placental abruption | BMC pregnancy and childbirth |
Increasing utilisation of perinatal services: estimating the impact of community health worker program in Neno, Malawi. | Kachimanga C, Dunbar EL, Watson S, Cundale K, Makungwa H, Wroe EB, Malindi C, Nazimera L, Palazuelos D, Drake J, Gates T, van den Akker T, Shea J | 2020-01-06 | Antenatal care, Community health workers, Deliveries, obstetric, Intrapartum care, Malawi, Maternal mortality, Perinatal care, Postnatal care, Synthetic control, quasi-experimental study | BMC pregnancy and childbirth |
Pre-post implementation survey of a multicomponent intervention to improve informed consent for caesarean section in Southern Malawi. | Zethof S, Bakker W, Nansongole F, Kilowe K, van Roosmalen J, van den Akker T | 2020-01-06 | caesarean section, informed consent, maternal medicine, medical ethics, quality in health care, tropical medicine | BMJ open |
Men Have a Stronger Monocyte-Derived Cytokine Production Response upon Stimulation with the Gram-Negative Stimulus Lipopolysaccharide than Women: A Pooled Analysis Including 15 Study Populations. | Beenakker KGM, Westendorp RGJ, de Craen AJM, Chen S, Raz Y, Ballieux BEPB, Nelissen RGHH, Later AFL, Huizinga TW, Slagboom PE, Boomsma DI, Maier AB | 2020-01-01 | Blood, Cytokines, Gender, Innate immunity, Lipopolysaccharide, Sex | Journal of innate immunity |
Basal cell carcinoma genetic susceptibility increases the rate of skin ageing: a Mendelian randomization study. | van der Poort EKJ, Gunn DA, Beekman M, Griffiths CEM, Slagboom PE, van Heemst D, Noordam R | 2020-01-01 | Journal of the European Academy of Dermatology and Venereology : JEADV | |
Ageing, age-related diseases and oxidative stress: What to do next? | Luo J, Mills K, le Cessie S, Noordam R, van Heemst D | 2020-01-01 | Age-related diseases, Ageing, Oxidative stress, Vitamin E metabolites | Ageing research reviews |
Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas. | Liu J, Lahousse L, Nivard MG, Bot M, Chen L, van Klinken JB, Thesing CS, Beekman M, van den Akker EB, Slieker RC, Waterham E, van der Kallen CJH, de Boer I, Li-Gao R, Vojinovic D, Amin N, Radjabzadeh D, Kraaij R, Alferink LJM, Murad SD, Uitterlinden AG, Willemsen G, Pool R, Milaneschi Y, van Heemst D, Suchiman HED, Rutters F, Elders PJM, Beulens JWJ, van der Heijden AAWA, van Greevenbroek MMJ, Arts ICW, Onderwater GLJ, van den Maagdenberg AMJM, Mook-Kanamori DO, Hankemeier T, Terwindt GM, Stehouwer CDA, Geleijnse JM, 't Hart LM, Slagboom PE, van Dijk KW, Zhernakova A, Fu J, Penninx BWJH, Boomsma DI, Demirkan A, Stricker BHC, van Duijn CM | 2020-01-01 | Nature medicine | |
Regional variations in childbirth interventions and their correlations with adverse outcomes, birthplace and care provider: A nationwide explorative study. | Seijmonsbergen-Schermers AE, Zondag DC, Nieuwenhuijze M, van den Akker T, Verhoeven CJ, Geerts CC, Schellevis FG, de Jonge A | 2020-01-01 | PloS one | |
Severe Hypertensive Disorders of Pregnancy in Eastern Ethiopia: Comparing the Original WHO and Adapted sub-Saharan African Maternal Near-Miss Criteria. | Tura AK, Scherjon S, Stekelenburg J, van Roosmalen J, van den Akker T, Zwart J | 2020-01-01 | hypertensive disorders of pregnancy, maternal mortality, maternal near-miss, severe maternal outcomes, sub-Saharan Africa | International journal of women's health |
The kidney, subclinical thyroid disease and cardiovascular outcomes in older patients. | Zijlstra LE, van Velzen DM, Simsek S, Mooijaart SP, van Buren M, Stott DJ, Ford I, Jukema JW, Trompet S | 2020-01-01 | cardiovascular disease, kidney function, older patients, thyroid function | Endocrine connections |
Renal Impairment, Cardiovascular Disease, and the Short-Term Efficacy and Safety of PCSK9 Targeted by Inclisiran. | Zijlstra LE, Trompet S, Mooijaart SP, van Buren M, Jukema JW | 2020-01-01 | Mayo Clinic proceedings | |
Skeletal Effects of Levothyroxine for Subclinical Hypothyroidism in Older Adults: A TRUST Randomized Trial Nested Study. | Gonzalez Rodriguez E, Stuber M, Del Giovane C, Feller M, Collet TH, Löwe AL, Blum MR, van Vliet NA, van Heemst D, Kearney PM, Gussekloo J, Mooijaart S, Westendorp RGJ, Stott DJ, Aeberli D, Bauer DC, Hans D, Rodondi N | 2020-01-01 | The Journal of clinical endocrinology and metabolism | |
Managing hypertension in frail oldest-old-The role of guideline use by general practitioners from 29 countries. | Roulet C, Rozsnyai Z, Jungo KT, A van der Ploeg M, Floriani C, Kurpas D, Vinker S, Kreitmayer Pestic S, Petrazzuoli F, Hoffmann K, Viegas RPA, Mallen C, Tatsioni A, Maisonneuve H, Collins C, Lingner H, Tsopra R, Mueller Y, Poortvliet RKE, Gussekloo J, Streit S | 2020-01-01 | PloS one | |
Potentially inappropriate medication and attitudes of older adults towards deprescribing. | Achterhof AB, Rozsnyai Z, Reeve E, Jungo KT, Floriani C, Poortvliet RKE, Rodondi N, Gussekloo J, Streit S | 2020-01-01 | PloS one | |
Small vessel disease lesion type and brain atrophy: The role of co-occurring amyloid. | Heinen R, Groeneveld ON, Barkhof F, de Bresser J, Exalto LG, Kuijf HJ, Prins ND, Scheltens P, van der Flier WM, Biessels GJ | 2020-01-01 | Alzheimer's disease, brain atrophy, cerebral microbleeds, cerebral small vessel disease, lacunes, magnetic resonance imaging, vascular cognitive impairment, white matter hyperintensities | Alzheimer's & dementia (Amsterdam, Netherlands) |
fMRI network correlates of predisposing risk factors for delirium: A cross-sectional study. | van Montfort SJT, Slooter AJC, Kant IMJ, van der Leur RR, Spies C, de Bresser J, Witkamp TD, Hendrikse J, van Dellen E | 2020-01-01 | Aging, Brain networks, Delirium, Functional connectivity, Graph theory, Risk factors | NeuroImage. Clinical |
CSF enhancement on post-contrast fluid-attenuated inversion recovery images; a systematic review. | Freeze WM, van der Thiel M, de Bresser J, Klijn CJM, van Etten ES, Jansen JFA, van der Weerd L, Jacobs HIL, Backes WH, van Veluw SJ | 2020-01-01 | Blood–brain barrier, Cerebrospinal fluid, Fluid-attenuated inversion recovery, Gadolinium, Neurological disease | NeuroImage. Clinical |
Cerebral Perfusion and the Burden of Small Vessel Disease in Patients Referred to a Memory Clinic. | Onkenhout L, Appelmans N, Kappelle LJ, Koek D, Exalto L, de Bresser J, Biessels GJ | 2020-01-01 | Cerebral perfusion, Enlarged perivascular spaces, Lacunes, Microbleeds, Small vessel disease, White matter hyperintesities | Cerebrovascular diseases (Basel, Switzerland) |
Suspected Transverse Myelitis with Normal MRI and CSF Findings in a Patient with Lupus: What to Do? A Case Series and Systematic Review. | Monahan RC, Beaart HJL, Fronczek R, Terwindt GM, Beaart-van de Voorde LJJ, de Bresser J, Kloppenburg M, van der Wee NJA, Huizinga TWJ, Steup-Beekman GM | 2020-01-01 | CSF, MRI, lupus, neuropsychiatric, transverse myelitis | Neuropsychiatric disease and treatment |
The Pain Assessment in Impaired Cognition scale (PAIC15): A multidisciplinary and international approach to develop and test a meta-tool for pain assessment in impaired cognition, especially dementia. | Kunz M, de Waal MWM, Achterberg WP, Gimenez-Llort L, Lobbezoo F, Sampson EL, van Dalen-Kok AH, Defrin R, Invitto S, Konstantinovic L, Oosterman J, Petrini L, van der Steen JT, Strand LI, de Tommaso M, Zwakhalen S, Husebo BS, Lautenbacher S | 2020-01-01 | European journal of pain (London, England) | |
The Prognostic Value of Metabolic Profiling in Older Patients With a Proximal Femoral Fracture. | van der Sijp MPL, Suchiman HED, Eijk M, Vojinovic D, Niggebrugge AHP, Blauw GJ, Achterberg WP, Slagboom PE | 2020-01-01 | biomarkers, metabolic profiling, metabolomics, prognostics, proximal femoral fracture | Geriatric orthopaedic surgery & rehabilitation |
Non-pharmacological interventions for improving quality of life of long-term care residents with dementia: a scoping review protocol. | Akintola AA, Achterberg WP, Caljouw MAA | 2019-12-23 | dementia, long-term care, non- pharmacological interventions, scoping review protocol | BMJ open |
Confidential enquiries into maternal deaths in Ondo State, Nigeria – a comparative analysis. | Oyeneyin L, van den Akker T, Durojaiye O, Obaado O, Akanbiemu F, Olagbuji Y, Aladeniyi I, Oyeneyin M, Aladenola O | 2019-12-21 | Confidential enquiries, Maternal deaths, Maternal mortality ratio | BMC pregnancy and childbirth |
PCSK9 inhibition in high-risk patients. | Zijlstra LE, Mooijaart SP, Jukema JW | 2019-12-11 | PCSK9 inhibiting, cardiovascular disease, lipid-lowering, older patients, plaque burden | Aging |
Nutritional Factors Modulating Alu Methylation in an Italian Sample from The Mark-Age Study Including Offspring of Healthy Nonagenarians. | Giacconi R, Malavolta M, Bürkle A, Moreno-Villanueva M, Franceschi C, Capri M, Slagboom PE, Jansen EHJM, Dollé MET, Grune T, Weber D, Hervonen A, Stuetz W, Breusing N, Ciccarone F, Zampieri M, Aversano V, Caiafa P, Formentini L, Piacenza F, Pierpaoli E, Basso A, Provinciali M, Cardelli M | 2019-12-06 | Alu methylation, aging, antioxidant, longevity, nutrients | Nutrients |
Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction. | Victorelli S, Lagnado A, Halim J, Moore W, Talbot D, Barrett K, Chapman J, Birch J, Ogrodnik M, Meves A, Pawlikowski JS, Jurk D, Adams PD, van Heemst D, Beekman M, Slagboom PE, Gunn DA, Passos JF | 2019-12-02 | SASP, melanocytes, senescence, skin ageing, telomeres | The EMBO journal |
Repeat variations in polyglutamine disease-associated genes and cognitive function in old age. | Gardiner SL, Trompet S, Sabayan B, Boogaard MW, Jukema JW, Slagboom PE, Roos RAC, van der Grond J, Aziz NA | 2019-12-01 | Cognitive function, Huntington disease, Missing heritability, Polyglutamine diseases, Polyglutamine disease–associated genes, Tandem repeats | Neurobiology of aging |
Viewpoint on the role of tissue maintenance in ageing: focus on biomarkers of bone, cartilage, muscle, and brain tissue maintenance. | van der Spoel E, van Vliet NA, van Heemst D | 2019-12-01 | Biomarkers, Bone, Brain, Cartilage, Muscle, Tissue maintenance | Ageing research reviews |
CAM-ICU may not be the optimal screening tool for early delirium screening in older emergency department patients: a prospective cohort study. | Lucke JA, De Gelder J, Blomaard LC, Fogteloo AJ, Alsma J, Schuit SCE, Brink A, De Groot B, Blauw GJ, Mooijaart SP | 2019-12-01 | European journal of emergency medicine : official journal of the European Society for Emergency Medicine | |
The association between lacunes and white matter hyperintensity features on MRI: The SMART-MR study. | Ghaznawi R, Geerlings MI, Jaarsma-Coes MG, Zwartbol MH, Kuijf HJ, van der Graaf Y, Witkamp TD, Hendrikse J, de Bresser J | 2019-12-01 | Small vessel disease, cerebrovascular disease, lacunes, magnetic resonance imaging, white matter hyperintensities | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism |
Nonfocal Transient Neurological Attacks Are Associated With Cerebral Small Vessel Disease. | Oudeman EA, Greving JP, Van den Berg-Vos RM, Biessels GJ, Bron EE, van Oostenbrugge R, de Bresser J, Kappelle LJ | 2019-12-01 | cerebral small vessel diseases, humans, magnetic resonance imaging, neurologic manifestations, odds ratio | Stroke |
What is geriatric rehabilitation and how should it be organized? A Delphi study aimed at reaching European consensus. | van Balen R, Gordon AL, Schols JMGA, Drewes YM, Achterberg WP | 2019-12-01 | Delphi procedure, European consensus, Geriatric rehabilitation | European geriatric medicine |
We’re all different and we’re the same: the story of the European nursing home resident. | Achterberg WP, Everink IH, van der Steen JT, Gordon AL | 2019-12-01 | Age and ageing | |
Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism. | Mooijaart SP, Du Puy RS, Stott DJ, Kearney PM, Rodondi N, Westendorp RGJ, den Elzen WPJ, Postmus I, Poortvliet RKE, van Heemst D, van Munster BC, Peeters RP, Ford I, Kean S, Messow CM, Blum MR, Collet TH, Watt T, Dekkers OM, Jukema JW, Smit JWA, Langhorne P, Gussekloo J | 2019-11-26 | JAMA | |
DNA methylation aging clocks: challenges and recommendations. | Bell CG, Lowe R, Adams PD, Baccarelli AA, Beck S, Bell JT, Christensen BC, Gladyshev VN, Heijmans BT, Horvath S, Ideker T, Issa JJ, Kelsey KT, Marioni RE, Reik W, Relton CL, Schalkwyk LC, Teschendorff AE, Wagner W, Zhang K, Rakyan VK | 2019-11-25 | Genome biology | |
[Screening for vulnerability in older adults attending the emergency department]. | van Dam CS, Trappenburg MC, Peters MJL, Blomaard LC, Lucke JA, Mooijaart SP | 2019-11-14 | Nederlands tijdschrift voor geneeskunde | |
Performance of five automated white matter hyperintensity segmentation methods in a multicenter dataset. | Heinen R, Steenwijk MD, Barkhof F, Biesbroek JM, van der Flier WM, Kuijf HJ, Prins ND, Vrenken H, Biessels GJ, de Bresser J | 2019-11-14 | Scientific reports | |
Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. | Noordam R, Bos MM, Wang H, Winkler TW, Bentley AR, Kilpeläinen TO, de Vries PS, Sung YJ, Schwander K, Cade BE, Manning A, Aschard H, Brown MR, Chen H, Franceschini N, Musani SK, Richard M, Vojinovic D, Aslibekyan S, Bartz TM, de Las Fuentes L, Feitosa M, Horimoto AR, Ilkov M, Kho M, Kraja A, Li C, Lim E, Liu Y, Mook-Kanamori DO, Rankinen T, Tajuddin SM, van der Spek A, Wang Z, Marten J, Laville V, Alver M, Evangelou E, Graff ME, He M, Kühnel B, Lyytikäinen LP, Marques-Vidal P, Nolte IM, Palmer ND, Rauramaa R, Shu XO, Snieder H, Weiss S, Wen W, Yanek LR, Adolfo C, Ballantyne C, Bielak L, Biermasz NR, Boerwinkle E, Dimou N, Eiriksdottir G, Gao C, Gharib SA, Gottlieb DJ, Haba-Rubio J, Harris TB, Heikkinen S, Heinzer R, Hixson JE, Homuth G, Ikram MA, Komulainen P, Krieger JE, Lee J, Liu J, Lohman KK, Luik AI, Mägi R, Martin LW, Meitinger T, Metspalu A, Milaneschi Y, Nalls MA, O'Connell J, Peters A, Peyser P, Raitakari OT, Reiner AP, Rensen PCN, Rice TK, Rich SS, Roenneberg T, Rotter JI, Schreiner PJ, Shikany J, Sidney SS, Sims M, Sitlani CM, Sofer T, Strauch K, Swertz MA, Taylor KD, Uitterlinden AG, van Duijn CM, Völzke H, Waldenberger M, Wallance RB, van Dijk KW, Yu C, Zonderman AB, Becker DM, Elliott P, Esko T, Gieger C, Grabe HJ, Lakka TA, Lehtimäki T, North KE, Penninx BWJH, Vollenweider P, Wagenknecht LE, Wu T, Xiang YB, Zheng W, Arnett DK, Bouchard C, Evans MK, Gudnason V, Kardia S, Kelly TN, Kritchevsky SB, Loos RJF, Pereira AC, Province M, Psaty BM, Rotimi C, Zhu X, Amin N, Cupples LA, Fornage M, Fox EF, Guo X, Gauderman WJ, Rice K, Kooperberg C, Munroe PB, Liu CT, Morrison AC, Rao DC, van Heemst D, Redline S | 2019-11-12 | Nature communications | |
[Assessment instruments in frail older patients; a call for more standardisation]. | Oud FMM, de Rooij SEJA, Arends AJ, Emmelot-Vonk MH, Melis RJF, Mooijaart SP, Willems HC, van Munster BC | 2019-11-12 | Nederlands tijdschrift voor geneeskunde | |
Validated inference of smoking habits from blood with a finite DNA methylation marker set. | Maas SCE, Vidaki A, Wilson R, Teumer A, Liu F, van Meurs JBJ, Uitterlinden AG, Boomsma DI, de Geus EJC, Willemsen G, van Dongen J, van der Kallen CJH, Slagboom PE, Beekman M, van Heemst D, van den Berg LH, Duijts L, Jaddoe VWV, Ladwig KH, Kunze S, Peters A, Ikram MA, Grabe HJ, Felix JF, Waldenberger M, Franco OH, Ghanbari M, Kayser M | 2019-11-01 | DNA methylation, Epidemiology, Epigenetics, Forensics, Smoking inference | European journal of epidemiology |
Comparison of outcome between intrauterine balloon tamponade and uterine artery embolization in the management of persistent postpartum hemorrhage: A propensity score-matched cohort study. | Ramler PI, Henriquez DDCA, van den Akker T, Caram-Deelder C, Groenwold RHH, Bloemenkamp KWM, van Roosmalen J, van Lith JMM, van der Bom JG | 2019-11-01 | intrauterine balloon tamponade, maternal mortality, peripartum hysterectomy, postpartum hemorrhage, propensity score, severe maternal outcome, uterine artery embolization | Acta obstetricia et gynecologica Scandinavica |
Risk factors, management, and outcomes of amniotic fluid embolism: A multicountry, population-based cohort and nested case-control study. | Fitzpatrick KE, van den Akker T, Bloemenkamp KWM, Deneux-Tharaux C, Kristufkova A, Li Z, Schaap TP, Sullivan EA, Tuffnell D, Knight M | 2019-11-01 | PLoS medicine | |
Standardized Assessment of Automatic Segmentation of White Matter Hyperintensities and Results of the WMH Segmentation Challenge. | Kuijf HJ, Biesbroek JM, De Bresser J, Heinen R, Andermatt S, Bento M, Berseth M, Belyaev M, Cardoso MJ, Casamitjana A, Collins DL, Dadar M, Georgiou A, Ghafoorian M, Jin D, Khademi A, Knight J, Li H, Llado X, Luna M, Mahmood Q, McKinley R, Mehrtash A, Ourselin S, Park BY, Park H, Park SH, Pezold S, Puybareau E, Rittner L, Sudre CH, Valverde S, Vilaplana V, Wiest R, Xu Y, Xu Z, Zeng G, Zhang J, Zheng G, Chen C, van der Flier W, Barkhof F, Viergever MA, Biessels GJ | 2019-11-01 | IEEE transactions on medical imaging | |
Quality of Life and Pain Medication Use in Persons With Advanced Dementia Living in Long-Term Care Facilities. | van Dam PH, Caljouw MAA, Slettebø DD, Achterberg WP, Husebo BS | 2019-11-01 | Quality of life, dementia, nursing home, pain medication, paracetamol | Journal of the American Medical Directors Association |
Systematic Review: Components of a Comprehensive Geriatric Assessment in Inflammatory Bowel Disease-A Potentially Promising but Often Neglected Risk Stratification. | Asscher VER, Lee-Kong FVY, Kort ED, van Deudekom FJ, Mooijaart SP, Maljaars PWJ | 2019-10-28 | Crohn’s disease, comprehensive geriatric assessment, ulcerative colitis | Journal of Crohn's & colitis |
Clinical characteristics of women captured by extending the definition of severe postpartum haemorrhage with ‘refractoriness to treatment’: a cohort study. | Henriquez DDCA, Gillissen A, Smith SM, Cramer RA, van den Akker T, Zwart JJ, van Roosmalen JJM, Bloemenkamp KWM, van der Bom JG | 2019-10-17 | Definition, Maternal morbidity, Maternal mortality, Postpartum haemorrhage | BMC pregnancy and childbirth |
Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults. | van Dongen J, Zilhão NR, Sugden K, Hannon EJ, Mill J, Caspi A, Agnew-Blais J, Arseneault L, Corcoran DL, Moffitt TE, Poulton R, Franke B, Boomsma DI | 2019-10-15 | ADHD, CAARS, DNA methylation, EWAS, Epigenetic, Meta-analysis | Biological psychiatry |
The use of goal attainment scaling during clinical medication review in older persons with polypharmacy. | Verdoorn S, Blom J, Vogelzang T, Kwint HF, Gussekloo J, Bouvy ML | 2019-10-01 | Clinical medication review, Drug-related problems, Goal attainment scaling, Older persons, Patient-centred care, Polypharmacy | Research in social & administrative pharmacy : RSAP |
Combined impact of future trends on healthcare utilisation of older people: A Delphi study. | Ravensbergen WM, Drewes YM, Hilderink HBM, Verschuuren M, Gussekloo J, Vonk RAA | 2019-10-01 | Ageing society, Delphi method, Healthcare planning, Population health foresight, Public health trends | Health policy (Amsterdam, Netherlands) |
The Association between Adult Weight Gain and Insulin Resistance at Middle Age: Mediation by Visceral Fat and Liver Fat. | Verkouter I, Noordam R, le Cessie S, van Dam RM, Lamb HJ, Rosendaal FR, van Heemst D, de Mutsert R | 2019-09-28 | body weight changes, fatty liver, insulin resistance, visceral fat | Journal of clinical medicine |
Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study. | Huang T, Wang T, Zheng Y, Ellervik C, Li X, Gao M, Fang Z, Chai JF, Ahluwalia TVS, Wang Y, Voortman T, Noordam R, Frazier-Wood A, Scholz M, Sonestedt E, Akiyama M, Dorajoo R, Zhou A, Kilpeläinen TO, Kleber ME, Crozier SR, Godfrey KM, Lemaitre R, Felix JF, Shi Y, Gupta P, Khor CC, Lehtimäki T, Wang CA, Tiesler CMT, Thiering E, Standl M, Rzehak P, Marouli E, He M, Lecoeur C, Corella D, Lai CQ, Moreno LA, Pitkänen N, Boreham CA, Zhang T, Saw SM, Ridker PM, Graff M, van Rooij FJA, Uitterlinden AG, Hofman A, van Heemst D, Rosendaal FR, de Mutsert R, Burkhardt R, Schulz CA, Ericson U, Kamatani Y, Yuan JM, Power C, Hansen T, Sørensen TIA, Tjønneland A, Overvad K, Delgado G, Cooper C, Djousse L, Rivadeneira F, Jameson K, Zhao W, Liu J, Lee NR, Raitakari O, Kähönen M, Viikari J, Grote V, Langhendries JP, Koletzko B, Escribano J, Verduci E, Dedoussis G, Yu C, Tham YC, Lim B, Lim SH, Froguel P, Balkau B, Fink NR, Vinding RK, Sevelsted A, Bisgaard H, Coltell O, Dallongeville J, Gottrand F, Pahkala K, Niinikoski H, Hyppönen E, Pedersen O, März W, Inskip H, Jaddoe VWV, Dennison E, Wong TY, Sabanayagam C, Tai ES, Mohlke KL, Mackey DA, Gruszfeld D, Deloukas P, Tucker KL, Fumeron F, Bønnelykke K, Rossing P, Estruch R, Ordovas JM, Arnett DK, Meirhaeghe A, Amouyel P, Cheng CY, Sim X, Teo YY, van Dam RM, Koh WP, Orho-Melander M, Loeffler M, Kubo M, Thiery J, Mook-Kanamori DO, Mozaffarian D, Psaty BM, Franco OH, Wu T, North KE, Davey Smith G, Chavarro JE, Chasman DI, Qi L | 2019-09-04 | JAMA network open | |
Statement on Minimum Standards for the Care of Older People in Emergency Departments by the Geriatric Emergency Medicine Special Interest Group of the International Federation for Emergency Medicine – ERRATUM. | Ellis B, Carpenter CR, Lowthian JA, Mooijaart SP, Nickel CH, Melady D | 2019-09-01 | CJEM | |
Associations of Elevated Antithyroperoxidase Antibodies with Thyroid Function, Survival, Functioning, and Depressive Symptoms in the Oldest Old: The Leiden 85-plus Study. | Du Puy RS, Poortvliet RKE, Snel M, den Elzen WPJ, Ballieux BEPB, Dekkers OM, Mooijaart SP, Gussekloo J | 2019-09-01 | Leiden 85-plus Study, TPOAb, antithyroperoxidase antibodies, oldest old, thyroid dysfunction | Thyroid : official journal of the American Thyroid Association |
Physical Performance in Memory Clinic Patients: The Potential Role of the White Matter Network. | Verwer JH, Reijmer YD, Koek HL, Biessels GJ | 2019-09-01 | brain connectivity, cognitive impairment, diffusion-weighted imaging, gait | Journal of the American Geriatrics Society |
Patient Characteristics and General Practitioners’ Advice to Stop Statins in Oldest-Old Patients: a Survey Study Across 30 Countries. | van der Ploeg MA, Streit S, Achterberg WP, Beers E, Bohnen AM, Burman RA, Collins C, Franco FG, Gerasimovska-Kitanovska B, Gintere S, Gomez Bravo R, Hoffmann K, Iftode C, Peštić SK, Koskela TH, Kurpas D, Maisonneuve H, Mallen CD, Merlo C, Mueller Y, Muth C, Petrazzuoli F, Rodondi N, Rosemann T, Sattler M, Schermer T, Šter MP, Švadlenková Z, Tatsioni A, Thulesius H, Tkachenko V, Torzsa P, Tsopra R, Tuz C, Vaes B, Viegas RPA, Vinker S, Wallis KA, Zeller A, Gussekloo J, Poortvliet RKE | 2019-09-01 | cardiovascular diseases, clinical decision-making, drug therapy, general practitioners, hydroxymethylglutaryl-CoA reductase inhibitors, palliative care | Journal of general internal medicine |
Pain assessment in impaired cognition: observer agreement in a long-term care setting in patients with dementia. | van Dalen-Kok AH, Achterberg WP, Rijkmans WE, de Vet HC, de Waal MW | 2019-09-01 | dementia, interobserver agreement, intraobserver agreement, nursing home, observational measurement instrument, pain, pain assessment, reliability | Pain management |
How can the quality of life of older patients living with chronic pain be improved? | Achterberg WP | 2019-09-01 | multimorbidity dementia, pain assessment, pain management, quality of life | Pain management |
Quality of essential newborn care and neonatal resuscitation at health facilities in Afghanistan: a cross-sectional assessment. | Atiqzai F, Manalai P, Amin SS, Edmond KM, Naziri M, Soroush MS, Sultana S, Yousufi K, van den Akker T, Stekelenburg J, Tappis H | 2019-08-30 | Afghanistan, essential newborn care, healthcare quality assessment, neonatal resuscitation, quality of healthcare | BMJ open |
Mistreatment of women in public health facilities of Ethiopia. | Sheferaw ED, Kim YM, van den Akker T, Stekelenburg J | 2019-08-27 | Disrespect and abuse, Ethiopia, Mistreatment, Respectful maternity care | Reproductive health |
Fast LC-ESI-MS/MS analysis and influence of sampling conditions for gut metabolites in plasma and serum. | van der Laan T, Kloots T, Beekman M, Kindt A, Dubbelman AC, Harms A, van Duijn CM, Slagboom PE, Hankemeier T | 2019-08-26 | Scientific reports | |
A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals. | Deelen J, Kettunen J, Fischer K, van der Spek A, Trompet S, Kastenmüller G, Boyd A, Zierer J, van den Akker EB, Ala-Korpela M, Amin N, Demirkan A, Ghanbari M, van Heemst D, Ikram MA, van Klinken JB, Mooijaart SP, Peters A, Salomaa V, Sattar N, Spector TD, Tiemeier H, Verhoeven A, Waldenberger M, Würtz P, Davey Smith G, Metspalu A, Perola M, Menni C, Geleijnse JM, Drenos F, Beekman M, Jukema JW, van Duijn CM, Slagboom PE | 2019-08-20 | Nature communications | |
Perspectives of Healthcare Professionals on Meaningful Activities for Persons with Dementia in Transition from Home to a Nursing Home: An Explorative Study. | Groenendaal M, Loor A, Trouw M, Achterberg WP, Caljouw MAA | 2019-08-19 | dementia, meaningful activities, nursing home, transition | Healthcare (Basel, Switzerland) |
A meta-analysis of genome-wide association studies identifies multiple longevity genes. | Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X, Wojczynski MK, Biggs ML, van der Spek A, Atzmon G, Ware EB, Sarnowski C, Smith AV, Seppälä I, Cordell HJ, Dose J, Amin N, Arnold AM, Ayers KL, Barzilai N, Becker EJ, Beekman M, Blanché H, Christensen K, Christiansen L, Collerton JC, Cubaynes S, Cummings SR, Davies K, Debrabant B, Deleuze JF, Duncan R, Faul JD, Franceschi C, Galan P, Gudnason V, Harris TB, Huisman M, Hurme MA, Jagger C, Jansen I, Jylhä M, Kähönen M, Karasik D, Kardia SLR, Kingston A, Kirkwood TBL, Launer LJ, Lehtimäki T, Lieb W, Lyytikäinen LP, Martin-Ruiz C, Min J, Nebel A, Newman AB, Nie C, Nohr EA, Orwoll ES, Perls TT, Province MA, Psaty BM, Raitakari OT, Reinders MJT, Robine JM, Rotter JI, Sebastiani P, Smith J, Sørensen TIA, Taylor KD, Uitterlinden AG, van der Flier W, van der Lee SJ, van Duijn CM, van Heemst D, Vaupel JW, Weir D, Ye K, Zeng Y, Zheng W, Holstege H, Kiel DP, Lunetta KL, Slagboom PE, Murabito JM | 2019-08-14 | Nature communications | |
Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium. | van der Spek A, Broer L, Draisma HHM, Pool R, Albrecht E, Beekman M, Mangino M, Raag M, Nyholt DR, Dharuri HK, Codd V, Amin N, de Geus EJC, Deelen J, Demirkan A, Yet I, Fischer K, Haller T, Henders AK, Isaacs A, Medland SE, Montgomery GW, Mooijaart SP, Strauch K, Suchiman HED, Vaarhorst AAM, van Heemst D, Wang-Sattler R, Whitfield JB, Willemsen G, Wright MJ, Martin NG, Samani NJ, Metspalu A, Eline Slagboom P, Spector TD, Boomsma DI, van Duijn CM, Gieger C | 2019-08-12 | Scientific reports | |
The association between frailty and MRI features of cerebral small vessel disease. | Kant IMJ, Mutsaerts HJMM, van Montfort SJT, Jaarsma-Coes MG, Witkamp TD, Winterer G, Spies CD, Hendrikse J, Slooter AJC, de Bresser J | 2019-08-05 | Scientific reports | |
Author Correction: L1 drives IFN in senescent cells and promotes age-associated inflammation. | De Cecco M, Ito T, Petrashen AP, Elias AE, Skvir NJ, Criscione SW, Caligiana A, Brocculi G, Adney EM, Boeke JD, Le O, Beauséjour C, Ambati J, Ambati K, Simon M, Seluanov A, Gorbunova V, Slagboom PE, Helfand SL, Neretti N, Sedivy JM | 2019-08-01 | Nature | |
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. | Watson HJ, Yilmaz Z, Thornton LM, Hübel C, Coleman JRI, Gaspar HA, Bryois J, Hinney A, Leppä VM, Mattheisen M, Medland SE, Ripke S, Yao S, Giusti-Rodríguez P, Hanscombe KB, Purves KL, Adan RAH, Alfredsson L, Ando T, Andreassen OA, Baker JH, Berrettini WH, Boehm I, Boni C, Perica VB, Buehren K, Burghardt R, Cassina M, Cichon S, Clementi M, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, Davis OSP, de Zwaan M, Dedoussis G, Degortes D, DeSocio JE, Dick DM, Dikeos D, Dina C, Dmitrzak-Weglarz M, Docampo E, Duncan LE, Egberts K, Ehrlich S, Escaramís G, Esko T, Estivill X, Farmer A, Favaro A, Fernández-Aranda F, Fichter MM, Fischer K, Föcker M, Foretova L, Forstner AJ, Forzan M, Franklin CS, Gallinger S, Giegling I, Giuranna J, Gonidakis F, Gorwood P, Mayora MG, Guillaume S, Guo Y, Hakonarson H, Hatzikotoulas K, Hauser J, Hebebrand J, Helder SG, Herms S, Herpertz-Dahlmann B, Herzog W, Huckins LM, Hudson JI, Imgart H, Inoko H, Janout V, Jiménez-Murcia S, Julià A, Kalsi G, Kaminská D, Kaprio J, Karhunen L, Karwautz A, Kas MJH, Kennedy JL, Keski-Rahkonen A, Kiezebrink K, Kim YR, Klareskog L, Klump KL, Knudsen GPS, La Via MC, Le Hellard S, Levitan RD, Li D, Lilenfeld L, Lin BD, Lissowska J, Luykx J, Magistretti PJ, Maj M, Mannik K, Marsal S, Marshall CR, Mattingsdal M, McDevitt S, McGuffin P, Metspalu A, Meulenbelt I, Micali N, Mitchell K, Monteleone AM, Monteleone P, Munn-Chernoff MA, Nacmias B, Navratilova M, Ntalla I, O'Toole JK, Ophoff RA, Padyukov L, Palotie A, Pantel J, Papezova H, Pinto D, Rabionet R, Raevuori A, Ramoz N, Reichborn-Kjennerud T, Ricca V, Ripatti S, Ritschel F, Roberts M, Rotondo A, Rujescu D, Rybakowski F, Santonastaso P, Scherag A, Scherer SW, Schmidt U, Schork NJ, Schosser A, Seitz J, Slachtova L, Slagboom PE, Slof-Op 't Landt MCT, Slopien A, Sorbi S, Świątkowska B, Szatkiewicz JP, Tachmazidou I, Tenconi E, Tortorella A, Tozzi F, Treasure J, Tsitsika A, Tyszkiewicz-Nwafor M, Tziouvas K, van Elburg AA, van Furth EF, Wagner G, Walton E, Widen E, Zeggini E, Zerwas S, Zipfel S, Bergen AW, Boden JM, Brandt H, Crawford S, Halmi KA, Horwood LJ, Johnson C, Kaplan AS, Kaye WH, Mitchell JE, Olsen CM, Pearson JF, Pedersen NL, Strober M, Werge T, Whiteman DC, Woodside DB, Stuber GD, Gordon S, Grove J, Henders AK, Juréus A, Kirk KM, Larsen JT, Parker R, Petersen L, Jordan J, Kennedy M, Montgomery GW, Wade TD, Birgegård A, Lichtenstein P, Norring C, Landén M, Martin NG, Mortensen PB, Sullivan PF, Breen G, Bulik CM | 2019-08-01 | Nature genetics | |
Associations of sleep duration and quality with serum and hepatic lipids: The Netherlands Epidemiology of Obesity Study. | Bos MM, Noordam R, van den Berg R, de Mutsert R, Rosendaal FR, Blauw GJ, Rensen PCN, Biermasz NR, van Heemst D | 2019-08-01 | cardiovascular diseases, lifestyle, lipids, obesity, sleep | Journal of sleep research |
Are skin senescence and immunosenescence linked within individuals? | Waaijer MEC, Goldeck D, Gunn DA, van Heemst D, Westendorp RGJ, Pawelec G, Maier AB | 2019-08-01 | cellular senescence, human, immunosenescence, skin aging | Aging cell |
Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression. | van der Plaat DA, Vonk JM, Terzikhan N, de Jong K, de Vries M, La Bastide-van Gemert S, van Diemen CC, Lahousse L, Brusselle GG, Nedeljkovic I, Amin N, Kromhout H, Vermeulen RCH, Postma DS, van Duijn CM, Boezen HM | 2019-08-01 | Human molecular genetics | |
Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals. | Mandaviya PR, Joehanes R, Brody J, Castillo-Fernandez JE, Dekkers KF, Do AN, Graff M, Hänninen IK, Tanaka T, de Jonge EAL, Kiefte-de Jong JC, Absher DM, Aslibekyan S, de Rijke YB, Fornage M, Hernandez DG, Hurme MA, Ikram MA, Jacques PF, Justice AE, Kiel DP, Lemaitre RN, Mendelson MM, Mikkilä V, Moore AZ, Pallister T, Raitakari OT, Schalkwijk CG, Sha J, Slagboom EPE, Smith CE, Stehouwer CDA, Tsai PC, Uitterlinden AG, van der Kallen CJH, van Heemst D, Arnett DK, Bandinelli S, Bell JT, Heijmans BT, Lehtimäki T, Levy D, North KE, Sotoodehnia N, van Greevenbroek MMJ, van Meurs JBJ, Heil SG | 2019-08-01 | DNA methylation, Epigenome-wide Association Study, FFQ, diet, epigenetics, folate, genome-wide, vitamin B-12 | The American journal of clinical nutrition |
Comparing Methods for Measurement Error Detection in Serial 24-h Hormonal Data. | van der Spoel E, Choi J, Roelfsema F, Cessie SL, van Heemst D, Dekkers OM | 2019-08-01 | automatic outlier detection, hormones, measurement error, outlier, time series | Journal of biological rhythms |
BMI-associated gene variants in FTO and cardiometabolic and brain disease: obesity or pleiotropy? | Ganeff IMM, Bos MM, van Heemst D, Noordam R | 2019-08-01 | brain disease, cardiometabolic disease, obesity, pleiotropy | Physiological genomics |
The impact of reclassifying suicides in pregnancy and in the postnatal period on maternal mortality ratios. | Lommerse K, Knight M, Nair M, Deneux-Tharaux C, van den Akker T | 2019-08-01 | BJOG : an international journal of obstetrics and gynaecology | |
Lessons learnt from anonymized review of cases of peripartum hysterectomy by international experts: A qualitative pilot study. | Jónasdóttir E, Aabakke AJM, Colmorn LB, Jakobsson M, Äyräs O, Baghestan E, Svanvik T, van den Akker T, Bloemenkamp K, van Roosmalen J, Krebs L, Knight M, Langhoff-Roos J | 2019-08-01 | case narrative, maternity care, obstetric complications, peripartum hysterectomy, qualitative audit | Acta obstetricia et gynecologica Scandinavica |
Maternal and perinatal outcomes of asylum seekers and undocumented migrants in Europe: a systematic review. | Gieles NC, Tankink JB, van Midde M, Düker J, van der Lans P, Wessels CM, Bloemenkamp KWM, Bonsel G, van den Akker T, Goosen S, Rijken MJ, Browne JL | 2019-08-01 | European journal of public health | |
Determinants of self-rated health in older adults before and 3 months after an emergency department visit: a prospective study. | Van Deudekom FJ, De Gelder J, Lucke JA, Oostendorp-Lange A, Anten S, Blauw GJ, De Groot B, Mooijaart SP | 2019-08-01 | European journal of emergency medicine : official journal of the European Society for Emergency Medicine | |
Geriatric assessment and 1-year mortality in older patients with cancer in the head and neck region: A cohort study. | van Deudekom FJ, van der Velden LA, Zijl WH, Schimberg AS, Langeveld AP, Slingerland M, Blauw GJ, Mooijaart SP | 2019-08-01 | cognitive disorders, geriatric oncology, head and neck cancer, physical functioning, social functioning | Head & neck |
Subclinical thyroid dysfunction and depressive symptoms: protocol for a systematic review and individual participant data meta-analysis of prospective cohort studies. | Wildisen L, Moutzouri E, Beglinger S, Syrogiannouli L, Cappola AR, Åsvold BO, Bakker SJL, Ceresini G, Dullaart R, Ferrucci L, Grabe H, Jukema JW, Nauck M, Trompet S, Völzke H, Westendorp RGJ, Gussekloo J, Peeters RP, Klöppel S, Aujesky D, Bauer DC, Rodondi N, Del Giovane C, Feller M | 2019-07-26 | depressive symptoms, individual participant data (IPD) meta-analysis, subclinical hyperthyroidism, subclinical hypothyroidism, subclinical thyroid dysfunction, systematic review | BMJ open |
Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits. | Porcu E, Rüeger S, Lepik K, Santoni FA, Reymond A, Kutalik Z | 2019-07-24 | Nature communications | |
Caffeine and neuropsychiatric symptoms in patients with dementia: A systematic review. | Kromhout MA, Rius Ottenheim N, Giltay E, Numans ME, Achterberg WP | 2019-07-15 | Behavior, Caffeine, Dementia, Neuropsychiatric symptoms, Sleep | Experimental gerontology |
Associations of Outdoor Temperature, Bright Sunlight, and Cardiometabolic Traits in Two European Population-Based Cohorts. | Noordam R, Ramkisoensing A, Loh NY, Neville MJ, Rosendaal FR, Willems van Dijk K, van Heemst D, Karpe F, Christodoulides C, Kooijman S | 2019-07-01 | The Journal of clinical endocrinology and metabolism | |
Physiological-based cord clamping in preterm infants using a new purpose-built resuscitation table: a feasibility study. | Brouwer E, Knol R, Vernooij ASN, van den Akker T, Vlasman PE, Klumper FJCM, DeKoninck P, Polglase GR, Hooper SB, Te Pas AB | 2019-07-01 | circulatory, neonatology, physiology, respiratory, resuscitation | Archives of disease in childhood. Fetal and neonatal edition |
A district-wide population-based descriptive study of emergency peripartum hysterectomy in a middle-income country. | Heitkamp A, Seinstra J, van den Akker T, Vollmer L, Gebhardt S, van Roosmalen J, de Vries JI, Theron G | 2019-07-01 | Emergency peripartum hysterectomy, High-risk pregnancy, Maternal mortality, Maternal near miss, Maternal sepsis, Obstetric surgery, Postpartum hemorrhage, Quality of obstetric care | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics |
A Prospective Cohort Study on the Effects of Geriatric Rehabilitation Following Acute Exacerbations of COPD. | van Dam van Isselt EF, van Eijk M, van Geloven N, Groenewegen-Sipkema KH, van den Berg JK, Nieuwenhuys CMA, Chavannes NH, Achterberg WP | 2019-07-01 | COPD, Geriatric rehabilitation, health status, post-acute PR, propensity score | Journal of the American Medical Directors Association |
Effects of the FIT-HIP Intervention for Fear of Falling After Hip Fracture: A Cluster-Randomized Controlled Trial in Geriatric Rehabilitation. | Scheffers-Barnhoorn MN, van Eijk M, van Haastregt JCM, Schols JMGA, van Balen R, van Geloven N, Kempen GIJM, Achterberg WP | 2019-07-01 | Fear of falling, cognitive behavioral therapy, geriatric rehabilitation, hip fracture, randomized controlled trial | Journal of the American Medical Directors Association |
Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals. | Noordam R, Young WJ, Salman R, Kanters JK, van den Berg ME, van Heemst D, Lin HJ, Barreto SM, Biggs ML, Biino G, Catamo E, Concas MP, Ding J, Evans DS, Foco L, Grarup N, Lyytikäinen LP, Mangino M, Mei H, van der Most PJ, Müller-Nurasyid M, Nelson CP, Qian Y, Repetto L, Said MA, Shah N, Schramm K, Vidigal PG, Weiss S, Yao J, Zilhao NR, Brody JA, Braund PS, Brumat M, Campana E, Christofidou P, Caulfield MJ, De Grandi A, Dominiczak AF, Doney ASF, Eiriksdottir G, Ellervik C, Giatti L, Gögele M, Graff C, Guo X, van der Harst P, Joshi PK, Kähönen M, Kestenbaum B, Lima-Costa MF, Linneberg A, Maan AC, Meitinger T, Padmanabhan S, Pattaro C, Peters A, Petersmann A, Sever P, Sinner MF, Shen X, Stanton A, Strauch K, Soliman EZ, Tarasov KV, Taylor KD, Thio CHL, Uitterlinden AG, Vaccargiu S, Waldenberger M, Robino A, Correa A, Cucca F, Cummings SR, Dörr M, Girotto G, Gudnason V, Hansen T, Heckbert SR, Juhl CR, Kääb S, Lehtimäki T, Liu Y, Lotufo PA, Palmer CNA, Pirastu M, Pramstaller PP, Ribeiro ALP, Rotter JI, Samani NJ, Snieder H, Spector TD, Stricker BH, Verweij N, Wilson JF, Wilson JG, Jukema JW, Tinker A, Newton-Cheh CH, Sotoodehnia N, Mook-Kanamori DO, Munroe PB, Warren HR | 2019-06-25 | cohort studies, electrocardiographic intervals, electrolytes, epidemiology, meta-analysis | Journal of the American College of Cardiology |
Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk. | Kurilshikov A, van den Munckhof ICL, Chen L, Bonder MJ, Schraa K, Rutten JHW, Riksen NP, de Graaf J, Oosting M, Sanna S, Joosten LAB, van der Graaf M, Brand T, Koonen DPY, van Faassen M, Slagboom PE, Xavier RJ, Kuipers F, Hofker MH, Wijmenga C, Netea MG, Zhernakova A, Fu J | 2019-06-07 | atherosclerosis, inflammation, metabolomics, metagenomics, microbiota | Circulation research |
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. | de Vries PS, Brown MR, Bentley AR, Sung YJ, Winkler TW, Ntalla I, Schwander K, Kraja AT, Guo X, Franceschini N, Cheng CY, Sim X, Vojinovic D, Huffman JE, Musani SK, Li C, Feitosa MF, Richard MA, Noordam R, Aschard H, Bartz TM, Bielak LF, Deng X, Dorajoo R, Lohman KK, Manning AK, Rankinen T, Smith AV, Tajuddin SM, Evangelou E, Graff M, Alver M, Boissel M, Chai JF, Chen X, Divers J, Gandin I, Gao C, Goel A, Hagemeijer Y, Harris SE, Hartwig FP, He M, Horimoto ARVR, Hsu FC, Jackson AU, Kasturiratne A, Komulainen P, Kühnel B, Laguzzi F, Lee JH, Luan J, Lyytikäinen LP, Matoba N, Nolte IM, Pietzner M, Riaz M, Said MA, Scott RA, Sofer T, Stančáková A, Takeuchi F, Tayo BO, van der Most PJ, Varga TV, Wang Y, Ware EB, Wen W, Yanek LR, Zhang W, Zhao JH, Afaq S, Amin N, Amini M, Arking DE, Aung T, Ballantyne C, Boerwinkle E, Broeckel U, Campbell A, Canouil M, Charumathi S, Chen YI, Connell JM, de Faire U, de Las Fuentes L, de Mutsert R, de Silva HJ, Ding J, Dominiczak AF, Duan Q, Eaton CB, Eppinga RN, Faul JD, Fisher V, Forrester T, Franco OH, Friedlander Y, Ghanbari M, Giulianini F, Grabe HJ, Grove ML, Gu CC, Harris TB, Heikkinen S, Heng CK, Hirata M, Hixson JE, Howard BV, Ikram MA, Jacobs DR, Johnson C, Jonas JB, Kammerer CM, Katsuya T, Khor CC, Kilpeläinen TO, Koh WP, Koistinen HA, Kolcic I, Kooperberg C, Krieger JE, Kritchevsky SB, Kubo M, Kuusisto J, Lakka TA, Langefeld CD, Langenberg C, Launer LJ, Lehne B, Lemaitre RN, Li Y, Liang J, Liu J, Liu K, Loh M, Louie T, Mägi R, Manichaikul AW, McKenzie CA, Meitinger T, Metspalu A, Milaneschi Y, Milani L, Mohlke KL, Mosley TH, Mukamal KJ, Nalls MA, Nauck M, Nelson CP, Sotoodehnia N, O'Connell JR, Palmer ND, Pazoki R, Pedersen NL, Peters A, Peyser PA, Polasek O, Poulter N, Raffel LJ, Raitakari OT, Reiner AP, Rice TK, Rich SS, Robino A, Robinson JG, Rose LM, Rudan I, Schmidt CO, Schreiner PJ, Scott WR, Sever P, Shi Y, Sidney S, Sims M, Smith BH, Smith JA, Snieder H, Starr JM, Strauch K, Tan N, Taylor KD, Teo YY, Tham YC, Uitterlinden AG, van Heemst D, Vuckovic D, Waldenberger M, Wang L, Wang Y, Wang Z, Wei WB, Williams C, Wilson G, Wojczynski MK, Yao J, Yu B, Yu C, Yuan JM, Zhao W, Zonderman AB, Becker DM, Boehnke M, Bowden DW, Chambers JC, Deary IJ, Esko T, Farrall M, Franks PW, Freedman BI, Froguel P, Gasparini P, Gieger C, Horta BL, Kamatani Y, Kato N, Kooner JS, Laakso M, Leander K, Lehtimäki T, Magnusson PKE, Penninx B, Pereira AC, Rauramaa R, Samani NJ, Scott J, Shu XO, van der Harst P, Wagenknecht LE, Wang YX, Wareham NJ, Watkins H, Weir DR, Wickremasinghe AR, Zheng W, Elliott P, North KE, Bouchard C, Evans MK, Gudnason V, Liu CT, Liu Y, Psaty BM, Ridker PM, van Dam RM, Kardia SLR, Zhu X, Rotimi CN, Mook-Kanamori DO, Fornage M, Kelly TN, Fox ER, Hayward C, van Duijn CM, Tai ES, Wong TY, Liu J, Rotter JI, Gauderman WJ, Province MA, Munroe PB, Rice K, Chasman DI, Cupples LA, Rao DC, Morrison AC | 2019-06-01 | alcohol consumption, cholesterol, gene-environment interactions, gene-lifestyle interactions, genome-wide association studies, lipids, triglycerides | American journal of epidemiology |
Women receiving massive transfusion due to postpartum hemorrhage: A comparison over time between two nationwide cohort studies. | Ramler PI, van den Akker T, Henriquez DDCA, Zwart JJ, van Roosmalen J, van Lith JMM, van der Bom JG | 2019-06-01 | blood transfusion, hysterectomy, morbidity, mortality, postpartum hemorrhage | Acta obstetricia et gynecologica Scandinavica |
Maternal cardiac arrest in the Netherlands: A nationwide surveillance study. | Schaap TP, Overtoom E, van den Akker T, Zwart JJ, van Roosmalen J, Bloemenkamp KWM | 2019-06-01 | Cardiac arrest, Maternal morbidity, Perimortem CS | European journal of obstetrics, gynecology, and reproductive biology |
Is Prolonged Labor Managed Adequately in Rural Rwandan Hospitals? | Kalisa R, Rulisa S, van den Akker T, van Roosmalen J | 2019-06-01 | Cesarean section, oxytocin, partograph, prolonged labor, vacuum extraction | African journal of reproductive health |
Prevalence of Carriers of Intermediate and Pathological Polyglutamine Disease-Associated Alleles Among Large Population-Based Cohorts. | Gardiner SL, Boogaard MW, Trompet S, de Mutsert R, Rosendaal FR, Gussekloo J, Jukema JW, Roos RAC, Aziz NA | 2019-06-01 | JAMA neurology | |
The Association between Habitual Sleep Duration and Sleep Quality with Glycemic Traits: Assessment by Cross-Sectional and Mendelian Randomization Analyses. | Bos MM, van Heemst D, Donga E, de Mutsert R, Rosendaal FR, Blauw GJ, Rensen PCN, Biermasz NR, Noordam R | 2019-05-15 | diabetes, epidemiology, insulin resistance, mendelian randomization, sleep | Journal of clinical medicine |
Metabolomics Profiling of Visceral Adipose Tissue: Results From MESA and the NEO Study. | Neeland IJ, Boone SC, Mook-Kanamori DO, Ayers C, Smit RAJ, Tzoulaki I, Karaman I, Boulange C, Vaidya D, Punjabi N, Allison M, Herrington DM, Jukema JW, Rosendaal FR, Lamb HJ, van Dijk KW, Greenland P, de Mutsert R | 2019-05-07 | adipose tissue, cohort, metabolite, metabolomics, obesity, visceral adipose tissue | Journal of the American Heart Association |
Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. | Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C, Hofer E, Ikram MA, Karlsson R, Knowles E, Lahti J, Leber M, Li S, Mather KA, Melle I, Morris D, Oldmeadow C, Palviainen T, Payton A, Pazoki R, Petrovic K, Reynolds CA, Sargurupremraj M, Scholz M, Smith JA, Smith AV, Terzikhan N, Thalamuthu A, Trompet S, van der Lee SJ, Ware EB, Windham BG, Wright MJ, Yang J, Yu J, Ames D, Amin N, Amouyel P, Andreassen OA, Armstrong NJ, Assareh AA, Attia JR, Attix D, Avramopoulos D, Bennett DA, Böhmer AC, Boyle PA, Brodaty H, Campbell H, Cannon TD, Cirulli ET, Congdon E, Conley ED, Corley J, Cox SR, Dale AM, Dehghan A, Dick D, Dickinson D, Eriksson JG, Evangelou E, Faul JD, Ford I, Freimer NA, Gao H, Giegling I, Gillespie NA, Gordon SD, Gottesman RF, Griswold ME, Gudnason V, Harris TB, Hartmann AM, Hatzimanolis A, Heiss G, Holliday EG, Joshi PK, Kähönen M, Kardia SLR, Karlsson I, Kleineidam L, Knopman DS, Kochan NA, Konte B, Kwok JB, Le Hellard S, Lee T, Lehtimäki T, Li SC, Lill CM, Liu T, Koini M, London E, Longstreth WT, Lopez OL, Loukola A, Luck T, Lundervold AJ, Lundquist A, Lyytikäinen LP, Martin NG, Montgomery GW, Murray AD, Need AC, Noordam R, Nyberg L, Ollier W, Papenberg G, Pattie A, Polasek O, Poldrack RA, Psaty BM, Reppermund S, Riedel-Heller SG, Rose RJ, Rotter JI, Roussos P, Rovio SP, Saba Y, Sabb FW, Sachdev PS, Satizabal CL, Schmid M, Scott RJ, Scult MA, Simino J, Slagboom PE, Smyrnis N, Soumaré A, Stefanis NC, Stott DJ, Straub RE, Sundet K, Taylor AM, Taylor KD, Tzoulaki I, Tzourio C, Uitterlinden A, Vitart V, Voineskos AN, Kaprio J, Wagner M, Wagner H, Weinhold L, Wen KH, Widen E, Yang Q, Zhao W, Adams HHH, Arking DE, Bilder RM, Bitsios P, Boerwinkle E, Chiba-Falek O, Corvin A, De Jager PL, Debette S, Donohoe G, Elliott P, Fitzpatrick AL, Gill M, Glahn DC, Hägg S, Hansell NK, Hariri AR, Ikram MK, Jukema JW, Vuoksimaa E, Keller MC, Kremen WS, Launer L, Lindenberger U, Palotie A, Pedersen NL, Pendleton N, Porteous DJ, Räikkönen K, Raitakari OT, Ramirez A, Reinvang I, Rudan I, Dan Rujescu, Schmidt R, Schmidt H, Schofield PW, Schofield PR, Starr JM, Steen VM, Trollor JN, Turner ST, Van Duijn CM, Villringer A, Weinberger DR, Weir DR, Wilson JF, Malhotra A, McIntosh AM, Gale CR, Seshadri S, Mosley TH, Bressler J, Lencz T, Deary IJ | 2019-05-01 | Nature communications | |
Women’s recommendations: vacuum extraction or caesarean section for prolonged second stage of labour, a prospective cohort study in Uganda. | Nolens B, van den Akker T, Lule J, Twinomuhangi S, van Roosmalen J, Byamugisha J | 2019-05-01 | accouchement, caesarean section, césarienne obstétricale, delivery, extraction sous vide, low- and middle-income countries, obstétrique, pays à revenu faible ou intermédiaire, préférences des femmes, vacuum extraction, women's preferences | Tropical medicine & international health : TM & IH |
Absence of the Association of Blood Pressure With Age in a Remote Venezuelan Population Renews the Call for Population-Wide Interventions. | Schalkwijk FH, van Bodegom D | 2019-05-01 | JAMA cardiology | |
Effects of a clinical medication review focused on personal goals, quality of life, and health problems in older persons with polypharmacy: A randomised controlled trial (DREAMeR-study). | Verdoorn S, Kwint HF, Blom JW, Gussekloo J, Bouvy ML | 2019-05-01 | PLoS medicine | |
Longitudinal assessment of the Unified Huntington’s Disease Rating Scale (UHDRS) and UHDRS-For Advanced Patients (UHDRS-FAP) in patients with late stage Huntington’s disease. | Winder JY, Achterberg WP, Gardiner SL, Roos RAC | 2019-05-01 | Huntington's disease, advanced stage, long-term care facility, longitudinal analysis, rating scales | European journal of neurology |
Psychosis symptoms in nursing home residents with and without dementia-Cross-sectional analyses from the COSMOS study. | Habiger TF, Achterberg WP, Flo E, Husebo BS | 2019-05-01 | dementia, neuropsychiatric symptoms, nursing home, pain, psychosis, psychotropic drugs, quality of life | International journal of geriatric psychiatry |
Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine. | Onderwater GLJ, Ligthart L, Bot M, Demirkan A, Fu J, van der Kallen CJH, Vijfhuizen LS, Pool R, Liu J, Vanmolkot FHM, Beekman M, Wen KX, Amin N, Thesing CS, Pijpers JA, Kies DA, Zielman R, de Boer I, van Greevenbroek MMJ, Arts ICW, Milaneschi Y, Schram MT, Dagnelie PC, Franke L, Ikram MA, Ferrari MD, Goeman JJ, Slagboom PE, Wijmenga C, Stehouwer CDA, Boomsma DI, van Duijn CM, Penninx BW, 't Hoen PAC, Terwindt GM, van den Maagdenberg AMJM | 2019-04-16 | Neurology | |
Clinical relevance of acute cerebral microinfarcts in vascular cognitive impairment. | Ferro DA, van den Brink H, Exalto LG, Boomsma JMF, Barkhof F, Prins ND, van der Flier WM, Biessels GJ | 2019-04-02 | Neurology | |
Adult weight change in relation to visceral fat and liver fat at middle age: The Netherlands epidemiology of obesity study. | Verkouter I, Noordam R, de Roos A, Lamb HJ, Rosendaal FR, van Heemst D, de Mutsert R | 2019-04-01 | International journal of obesity (2005) | |
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. | Bentley AR, Sung YJ, Brown MR, Winkler TW, Kraja AT, Ntalla I, Schwander K, Chasman DI, Lim E, Deng X, Guo X, Liu J, Lu Y, Cheng CY, Sim X, Vojinovic D, Huffman JE, Musani SK, Li C, Feitosa MF, Richard MA, Noordam R, Baker J, Chen G, Aschard H, Bartz TM, Ding J, Dorajoo R, Manning AK, Rankinen T, Smith AV, Tajuddin SM, Zhao W, Graff M, Alver M, Boissel M, Chai JF, Chen X, Divers J, Evangelou E, Gao C, Goel A, Hagemeijer Y, Harris SE, Hartwig FP, He M, Horimoto ARVR, Hsu FC, Hung YJ, Jackson AU, Kasturiratne A, Komulainen P, Kühnel B, Leander K, Lin KH, Luan J, Lyytikäinen LP, Matoba N, Nolte IM, Pietzner M, Prins B, Riaz M, Robino A, Said MA, Schupf N, Scott RA, Sofer T, Stancáková A, Takeuchi F, Tayo BO, van der Most PJ, Varga TV, Wang TD, Wang Y, Ware EB, Wen W, Xiang YB, Yanek LR, Zhang W, Zhao JH, Adeyemo A, Afaq S, Amin N, Amini M, Arking DE, Arzumanyan Z, Aung T, Ballantyne C, Barr RG, Bielak LF, Boerwinkle E, Bottinger EP, Broeckel U, Brown M, Cade BE, Campbell A, Canouil M, Charumathi S, Chen YI, Christensen K, Concas MP, Connell JM, de Las Fuentes L, de Silva HJ, de Vries PS, Doumatey A, Duan Q, Eaton CB, Eppinga RN, Faul JD, Floyd JS, Forouhi NG, Forrester T, Friedlander Y, Gandin I, Gao H, Ghanbari M, Gharib SA, Gigante B, Giulianini F, Grabe HJ, Gu CC, Harris TB, Heikkinen S, Heng CK, Hirata M, Hixson JE, Ikram MA, Jia Y, Joehanes R, Johnson C, Jonas JB, Justice AE, Katsuya T, Khor CC, Kilpeläinen TO, Koh WP, Kolcic I, Kooperberg C, Krieger JE, Kritchevsky SB, Kubo M, Kuusisto J, Lakka TA, Langefeld CD, Langenberg C, Launer LJ, Lehne B, Lewis CE, Li Y, Liang J, Lin S, Liu CT, Liu J, Liu K, Loh M, Lohman KK, Louie T, Luzzi A, Mägi R, Mahajan A, Manichaikul AW, McKenzie CA, Meitinger T, Metspalu A, Milaneschi Y, Milani L, Mohlke KL, Momozawa Y, Morris AP, Murray AD, Nalls MA, Nauck M, Nelson CP, North KE, O'Connell JR, Palmer ND, Papanicolau GJ, Pedersen NL, Peters A, Peyser PA, Polasek O, Poulter N, Raitakari OT, Reiner AP, Renström F, Rice TK, Rich SS, Robinson JG, Rose LM, Rosendaal FR, Rudan I, Schmidt CO, Schreiner PJ, Scott WR, Sever P, Shi Y, Sidney S, Sims M, Smith JA, Snieder H, Starr JM, Strauch K, Stringham HM, Tan NYQ, Tang H, Taylor KD, Teo YY, Tham YC, Tiemeier H, Turner ST, Uitterlinden AG, van Heemst D, Waldenberger M, Wang H, Wang L, Wang L, Wei WB, Williams CA, Wilson G, Wojczynski MK, Yao J, Young K, Yu C, Yuan JM, Zhou J, Zonderman AB, Becker DM, Boehnke M, Bowden DW, Chambers JC, Cooper RS, de Faire U, Deary IJ, Elliott P, Esko T, Farrall M, Franks PW, Freedman BI, Froguel P, Gasparini P, Gieger C, Horta BL, Juang JJ, Kamatani Y, Kammerer CM, Kato N, Kooner JS, Laakso M, Laurie CC, Lee IT, Lehtimäki T, Magnusson PKE, Oldehinkel AJ, Penninx BWJH, Pereira AC, Rauramaa R, Redline S, Samani NJ, Scott J, Shu XO, van der Harst P, Wagenknecht LE, Wang JS, Wang YX, Wareham NJ, Watkins H, Weir DR, Wickremasinghe AR, Wu T, Zeggini E, Zheng W, Bouchard C, Evans MK, Gudnason V, Kardia SLR, Liu Y, Psaty BM, Ridker PM, van Dam RM, Mook-Kanamori DO, Fornage M, Province MA, Kelly TN, Fox ER, Hayward C, van Duijn CM, Tai ES, Wong TY, Loos RJF, Franceschini N, Rotter JI, Zhu X, Bierut LJ, Gauderman WJ, Rice K, Munroe PB, Morrison AC, Rao DC, Rotimi CN, Cupples LA | 2019-04-01 | Nature genetics | |
Vacuum extraction for non-rotational and rotational assisted vaginal birth. | van den Akker T | 2019-04-01 | Labour stage, Obstetrical, Obstetrics, Pregnancy, Second, Vacuum extraction | Best practice & research. Clinical obstetrics & gynaecology |
Use of assisted vaginal birth to reduce unnecessary caesarean sections and improve maternal and perinatal outcomes. | Nolens B, Capelle M, van Roosmalen J, Mola G, Byamugisha J, Lule J, Faye A, van den Akker T | 2019-04-01 | The Lancet. Global health | |
Predictive value of a bleeding score for postpartum hemorrhage. | Gillissen A, van den Akker T, Caram-Deelder C, Henriquez DDCA, Nij Bijvank SWA, Bloemenkamp KWM, Eikenboom J, van der Bom JG | 2019-04-01 | bleeding assessment tool, bleeding score, postpartum hemorrhage, prediction, pregnancy | Research and practice in thrombosis and haemostasis |
Geriatric emergency medicine: time for a new approach on a European level. | Mooijaart SP, Lucke JA, Brabrand M, Conroy S, Nickel CH | 2019-04-01 | European journal of emergency medicine : official journal of the European Society for Emergency Medicine | |
Low thyroid function is not associated with an accelerated deterioration in renal function. | Meuwese CL, van Diepen M, Cappola AR, Sarnak MJ, Shlipak MG, Bauer DC, Fried LP, Iacoviello M, Vaes B, Degryse J, Khaw KT, Luben RN, Åsvold BO, Bjøro T, Vatten LJ, de Craen AJM, Trompet S, Iervasi G, Molinaro S, Ceresini G, Ferrucci L, Dullaart RPF, Bakker SJL, Jukema JW, Kearney PM, Stott DJ, Peeters RP, Franco OH, Völzke H, Walsh JP, Bremner A, Sgarbi JA, Maciel RMB, Imaizumi M, Ohishi W, Dekker FW, Rodondi N, Gussekloo J, den Elzen WPJ | 2019-04-01 | CKD, chronic renal failure, creatinine clearance, epidemiology, thyroid function | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association |
The prevalence and the burden of pain in patients with Huntington disease: a systematic review and meta-analysis. | Sprenger GP, van der Zwaan KF, Roos RAC, Achterberg WP | 2019-04-01 | Pain | |
Geriatric Rehabilitation-State of the Art and Future Priorities. | Achterberg WP, Cameron ID, Bauer JM, Schols JM | 2019-04-01 | Journal of the American Medical Directors Association | |
Repeat length variations in polyglutamine disease-associated genes affect body mass index. | Gardiner SL, de Mutsert R, Trompet S, Boogaard MW, van Dijk KW, Jukema PJW, Slagboom PE, Roos RAC, Pijl H, Rosendaal FR, Aziz NA | 2019-03-01 | International journal of obesity (2005) | |
The 24-hour serum profiles of bone markers in healthy older men and women. | van der Spoel E, Oei N, Cachucho R, Roelfsema F, Berbée JFP, Blauw GJ, Pijl H, Appelman-Dijkstra NM, van Heemst D | 2019-03-01 | 24-hour profile, Bone markers, Circadian rhythm, Cosinor analysis, Sex differences | Bone |
Mendelian randomization reveals unexpected effects of CETP on the lipoprotein profile. | Blauw LL, Noordam R, Soidinsalo S, Blauw CA, Li-Gao R, de Mutsert R, Berbée JFP, Wang Y, van Heemst D, Rosendaal FR, Jukema JW, Mook-Kanamori DO, Würtz P, Willems van Dijk K, Rensen PCN | 2019-03-01 | European journal of human genetics : EJHG | |
Skewed X-inactivation is common in the general female population. | Shvetsova E, Sofronova A, Monajemi R, Gagalova K, Draisma HHM, White SJ, Santen GWE, Chuva de Sousa Lopes SM, Heijmans BT, van Meurs J, Jansen R, Franke L, Kiełbasa SM, den Dunnen JT, 't Hoen PAC | 2019-03-01 | European journal of human genetics : EJHG | |
A national surveillance approach to monitor incidence of eclampsia: The Netherlands Obstetric Surveillance System. | Schaap TP, van den Akker T, Zwart JJ, van Roosmalen J, Bloemenkamp KWM | 2019-03-01 | INOSS, NethOSS, eclampsia, maternal morbidity, obstetric surveillance system | Acta obstetricia et gynecologica Scandinavica |
Erythrocyte sedimentation rate as an independent prognostic marker for mortality: a prospective population-based cohort study. | Fest J, Ruiter R, Mooijaart SP, Ikram MA, van Eijck CHJ, Stricker BH | 2019-03-01 | ageing, erythrocyte sedimentation rate, general population, low-grade inflammation, mortality | Journal of internal medicine |
Systolic Blood Pressure and Cognitive Decline in Older Adults With Hypertension. | Streit S, Poortvliet RKE, Elzen WPJD, Blom JW, Gussekloo J | 2019-03-01 | cognitive function, daily functioning, hypertension, old age, quality of life | Annals of family medicine |
Applicability of the WHO maternal near miss tool in sub-Saharan Africa: a systematic review. | Tura AK, Trang TL, van den Akker T, van Roosmalen J, Scherjon S, Zwart J, Stekelenburg J | 2019-02-26 | Maternal near miss, Severe acute maternal morbidity, Severe maternal outcomes, Sub-Saharan Africa, Systematic review | BMC pregnancy and childbirth |
Metabolomic and lipidomic assessment of the metabolic syndrome in Dutch middle-aged individuals reveals novel biological signatures separating health and disease. | Surowiec I, Noordam R, Bennett K, Beekman M, Slagboom PE, Lundstedt T, van Heemst D | 2019-02-12 | Epidemiology, Lipidomics, Metabolic syndrome, Metabolomics | Metabolomics : Official journal of the Metabolomic Society |
RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage. | Coutinho de Almeida R, Ramos YFM, Mahfouz A, den Hollander W, Lakenberg N, Houtman E, van Hoolwerff M, Suchiman HED, Rodríguez Ruiz A, Slagboom PE, Mei H, Kiełbasa SM, Nelissen RGHH, Reinders M, Meulenbelt I | 2019-02-01 | data integration, mRNA, microRNAs, osteoarthritis, regulatory networks | Annals of the rheumatic diseases |
L1 drives IFN in senescent cells and promotes age-associated inflammation. | De Cecco M, Ito T, Petrashen AP, Elias AE, Skvir NJ, Criscione SW, Caligiana A, Brocculi G, Adney EM, Boeke JD, Le O, Beauséjour C, Ambati J, Ambati K, Simon M, Seluanov A, Gorbunova V, Slagboom PE, Helfand SL, Neretti N, Sedivy JM | 2019-02-01 | Nature | |
Defining definitions: a Delphi study to develop a core outcome set for conditions of severe maternal morbidity. | Schaap T, Bloemenkamp K, Deneux-Tharaux C, Knight M, Langhoff-Roos J, Sullivan E, van den Akker T | 2019-02-01 | Abnormally invasive placentation, Delphi, amniotic fluid embolism, cardiac arrest in pregnancy, eclampsia, pregnancy-related hysterectomy, severe acute maternal morbidity, severe primary postpartum haemorrhage, spontaneous hemoperitoneum in pregnancy, uterine rupture | BJOG : an international journal of obstetrics and gynaecology |
Comparison of thromboelastometry by ROTEM® Delta and ROTEM® Sigma in women with postpartum haemorrhage. | Gillissen A, van den Akker T, Caram-Deelder C, Henriquez DDCA, Bloemenkamp KWM, Eikenboom J, van der Bom JG, de Maat MPM | 2019-02-01 | ROTEM Delta, ROTEM Sigma, Thromboelastometry, comparison, postpartum haemorrhage | Scandinavian journal of clinical and laboratory investigation |
Acute care assessment of older adults living with frailty. | Quinn TJ, Mooijaart SP, Gallacher K, Burton JK | 2019-01-31 | BMJ (Clinical research ed.) | |
Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. | Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Guðnason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hernández MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Muñoz Maniega S, Slagboom PE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, Hosten N, von Sarnowski B, Völker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow CLM, Rosand J, Woo D, Cole JW, Meschia JF, Slowik A, Thijs V, Lindgren A, Melander O, Grewal RP, Rundek T, Rexrode K, Rothwell PM, Arnett DK, Jern C, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Wong Q, Mitchell BD, Rich SS, McArdle PF, Geerlings MI, van der Graaf Y, de Bakker PIW, Asselbergs FW, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs LCA, Bevan S, Tzourio C, Mather KA, Sachdev PS, van Duijn CM, Worrall BB, Dichgans M, Kittner SJ, Markus HS, Ikram MA, Fornage M, Launer LJ, Seshadri S, Longstreth WT, Debette S | 2019-01-28 | Neurology | |
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. | Kilpeläinen TO, Bentley AR, Noordam R, Sung YJ, Schwander K, Winkler TW, Jakupović H, Chasman DI, Manning A, Ntalla I, Aschard H, Brown MR, de Las Fuentes L, Franceschini N, Guo X, Vojinovic D, Aslibekyan S, Feitosa MF, Kho M, Musani SK, Richard M, Wang H, Wang Z, Bartz TM, Bielak LF, Campbell A, Dorajoo R, Fisher V, Hartwig FP, Horimoto ARVR, Li C, Lohman KK, Marten J, Sim X, Smith AV, Tajuddin SM, Alver M, Amini M, Boissel M, Chai JF, Chen X, Divers J, Evangelou E, Gao C, Graff M, Harris SE, He M, Hsu FC, Jackson AU, Zhao JH, Kraja AT, Kühnel B, Laguzzi F, Lyytikäinen LP, Nolte IM, Rauramaa R, Riaz M, Robino A, Rueedi R, Stringham HM, Takeuchi F, van der Most PJ, Varga TV, Verweij N, Ware EB, Wen W, Li X, Yanek LR, Amin N, Arnett DK, Boerwinkle E, Brumat M, Cade B, Canouil M, Chen YI, Concas MP, Connell J, de Mutsert R, de Silva HJ, de Vries PS, Demirkan A, Ding J, Eaton CB, Faul JD, Friedlander Y, Gabriel KP, Ghanbari M, Giulianini F, Gu CC, Gu D, Harris TB, He J, Heikkinen S, Heng CK, Hunt SC, Ikram MA, Jonas JB, Koh WP, Komulainen P, Krieger JE, Kritchevsky SB, Kutalik Z, Kuusisto J, Langefeld CD, Langenberg C, Launer LJ, Leander K, Lemaitre RN, Lewis CE, Liang J, Liu J, Mägi R, Manichaikul A, Meitinger T, Metspalu A, Milaneschi Y, Mohlke KL, Mosley TH, Murray AD, Nalls MA, Nang EK, Nelson CP, Nona S, Norris JM, Nwuba CV, O'Connell J, Palmer ND, Papanicolau GJ, Pazoki R, Pedersen NL, Peters A, Peyser PA, Polasek O, Porteous DJ, Poveda A, Raitakari OT, Rich SS, Risch N, Robinson JG, Rose LM, Rudan I, Schreiner PJ, Scott RA, Sidney SS, Sims M, Smith JA, Snieder H, Sofer T, Starr JM, Sternfeld B, Strauch K, Tang H, Taylor KD, Tsai MY, Tuomilehto J, Uitterlinden AG, van der Ende MY, van Heemst D, Voortman T, Waldenberger M, Wennberg P, Wilson G, Xiang YB, Yao J, Yu C, Yuan JM, Zhao W, Zonderman AB, Becker DM, Boehnke M, Bowden DW, de Faire U, Deary IJ, Elliott P, Esko T, Freedman BI, Froguel P, Gasparini P, Gieger C, Kato N, Laakso M, Lakka TA, Lehtimäki T, Magnusson PKE, Oldehinkel AJ, Penninx BWJH, Samani NJ, Shu XO, van der Harst P, Van Vliet-Ostaptchouk JV, Vollenweider P, Wagenknecht LE, Wang YX, Wareham NJ, Weir DR, Wu T, Zheng W, Zhu X, Evans MK, Franks PW, Gudnason V, Hayward C, Horta BL, Kelly TN, Liu Y, North KE, Pereira AC, Ridker PM, Tai ES, van Dam RM, Fox ER, Kardia SLR, Liu CT, Mook-Kanamori DO, Province MA, Redline S, van Duijn CM, Rotter JI, Kooperberg CB, Gauderman WJ, Psaty BM, Rice K, Munroe PB, Fornage M, Cupples LA, Rotimi CN, Morrison AC, Rao DC, Loos RJF | 2019-01-22 | Nature communications | |
Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait. | van den Berg N, Rodríguez-Girondo M, van Dijk IK, Mourits RJ, Mandemakers K, Janssens AAPO, Beekman M, Smith KR, Slagboom PE | 2019-01-07 | Nature communications | |
The association between intravenous fluid resuscitation and mortality in older emergency department patients with suspected infection. | Ko SY, Esteve Cuevas LM, Willeboer M, Ansems A, Blomaard LC, Lucke JA, Mooijaart SP, de Groot B | 2019-01-05 | Emergency medicine, Fluid resuscitation, Geriatrics, Infectious diseases, Sepsis, Systolic blood pressure | International journal of emergency medicine |
Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits. | Kraja AT, Liu C, Fetterman JL, Graff M, Have CT, Gu C, Yanek LR, Feitosa MF, Arking DE, Chasman DI, Young K, Ligthart S, Hill WD, Weiss S, Luan J, Giulianini F, Li-Gao R, Hartwig FP, Lin SJ, Wang L, Richardson TG, Yao J, Fernandez EP, Ghanbari M, Wojczynski MK, Lee WJ, Argos M, Armasu SM, Barve RA, Ryan KA, An P, Baranski TJ, Bielinski SJ, Bowden DW, Broeckel U, Christensen K, Chu AY, Corley J, Cox SR, Uitterlinden AG, Rivadeneira F, Cropp CD, Daw EW, van Heemst D, de Las Fuentes L, Gao H, Tzoulaki I, Ahluwalia TS, de Mutsert R, Emery LS, Erzurumluoglu AM, Perry JA, Fu M, Forouhi NG, Gu Z, Hai Y, Harris SE, Hemani G, Hunt SC, Irvin MR, Jonsson AE, Justice AE, Kerrison ND, Larson NB, Lin KH, Love-Gregory LD, Mathias RA, Lee JH, Nauck M, Noordam R, Ong KK, Pankow J, Patki A, Pattie A, Petersmann A, Qi Q, Ribel-Madsen R, Rohde R, Sandow K, Schnurr TM, Sofer T, Starr JM, Taylor AM, Teumer A, Timpson NJ, de Haan HG, Wang Y, Weeke PE, Williams C, Wu H, Yang W, Zeng D, Witte DR, Weir BS, Wareham NJ, Vestergaard H, Turner ST, Torp-Pedersen C, Stergiakouli E, Sheu WH, Rosendaal FR, Ikram MA, Franco OH, Ridker PM, Perls TT, Pedersen O, Nohr EA, Newman AB, Linneberg A, Langenberg C, Kilpeläinen TO, Kardia SLR, Jørgensen ME, Jørgensen T, Sørensen TIA, Homuth G, Hansen T, Goodarzi MO, Deary IJ, Christensen C, Chen YI, Chakravarti A, Brandslund I, Bonnelykke K, Taylor KD, Wilson JG, Rodriguez S, Davies G, Horta BL, Thyagarajan B, Rao DC, Grarup N, Davila-Roman VG, Hudson G, Guo X, Arnett DK, Hayward C, Vaidya D, Mook-Kanamori DO, Tiwari HK, Levy D, Loos RJF, Dehghan A, Elliott P, Malik AN, Scott RA, Becker DM, de Andrade M, Province MA, Meigs JB, Rotter JI, North KE | 2019-01-03 | BMI, HOMA-B, HOMA-IR, HbA1c, MT-nDNA candidate genes, glucose, insulin, mitochondria, mtDNA, waist-to-hip ratio | American journal of human genetics |
Antioxidants linked with physical, cognitive and psychological frailty: Analysis of candidate biomarkers and markers derived from the MARK-AGE study. | Rietman ML, Spijkerman AMW, Wong A, van Steeg H, Bürkle A, Moreno-Villanueva M, Sindlinger T, Franceschi C, Grubeck-Loebenstein B, Bernhardt J, Slagboom PE, Toussaint O, Debacq-Chainiaux F, Sikora E, Gonos ES, Breusing N, Stuetz W, Weber D, Grune T, Basso A, Piacenza F, Malavolta M, Collino S, Jansen EHJM, Verschuren WMM, Dollé MET | 2019-01-01 | Ageing, Elastic net, Frailty, Machine learning, Multidimensional, Multivariate, Univariate | Mechanisms of ageing and development |
Frailty Questionnaire Is Not a Strong Prognostic Factor for Functional Outcomes in Hip or Knee Arthroplasty Patients. | Meessen JMTA, Fiocco M, Leichtenberg CS, Vliet Vlieland TPM, Slagboom PE, Nelissen RGHH | 2019-01-01 | arthroplasty, frailty, osteoarthritis, rehabilitation | Geriatric orthopaedic surgery & rehabilitation |
The ApoE ε4 Isoform: Can the Risk of Diseases be Reduced by Environmental Factors? | Bos MM, Noordam R, Blauw GJ, Slagboom PE, Rensen PCN, van Heemst D | 2019-01-01 | The journals of gerontology. Series A, Biological sciences and medical sciences | |
A linear mixed-model approach to study multivariate gene-environment interactions. | Moore R, Casale FP, Jan Bonder M, Horta D, Franke L, Barroso I, Stegle O | 2019-01-01 | Nature genetics | |
A genome-wide association study identifies genetic loci associated with specific lobar brain volumes. | van der Lee SJ, Knol MJ, Chauhan G, Satizabal CL, Smith AV, Hofer E, Bis JC, Hibar DP, Hilal S, van den Akker EB, Arfanakis K, Bernard M, Yanek LR, Amin N, Crivello F, Cheung JW, Harris TB, Saba Y, Lopez OL, Li S, van der Grond J, Yu L, Paus T, Roshchupkin GV, Amouyel P, Jahanshad N, Taylor KD, Yang Q, Mathias RA, Boehringer S, Mazoyer B, Rice K, Cheng CY, Maillard P, van Heemst D, Wong TY, Niessen WJ, Beiser AS, Beekman M, Zhao W, Nyquist PA, Chen C, Launer LJ, Psaty BM, Ikram MK, Vernooij MW, Schmidt H, Pausova Z, Becker DM, De Jager PL, Thompson PM, van Duijn CM, Bennett DA, Slagboom PE, Schmidt R, Longstreth WT, Ikram MA, Seshadri S, Debette S, Gudnason V, Adams HHH, DeCarli C | 2019-01-01 | Biomarkers, Genome-wide association studies, Neurology | Communications biology |
Effectiveness of Stabilization of Preterm Infants With Intact Umbilical Cord Using a Purpose-Built Resuscitation Table-Study Protocol for a Randomized Controlled Trial. | Knol R, Brouwer E, Klumper FJCM, van den Akker T, DeKoninck P, Hutten GJ, Lopriore E, van Kaam AH, Polglase GR, Reiss IKM, Hooper SB, Te Pas AB | 2019-01-01 | newborn transition, physiological-based cord clamping, preterm infants, randomized controlled trial, resuscitation, study protocol, umbilical cord clamping | Frontiers in pediatrics |
Measuring maternal near-miss in a middle-income country: assessing the use of WHO and sub-Saharan Africa maternal near-miss criteria in Namibia. | Heemelaar S, Kabongo L, Ithindi T, Luboya C, Munetsi F, Bauer AK, Dammann A, Drewes A, Stekelenburg J, van den Akker T, Mackenzie S | 2019-01-01 | Maternal morbidity, WHO maternal near-miss criteria, middle-income setting, morbidity registration, near-miss approach, severe maternal outcome, sub-Saharan Africa maternal near-miss criteria | Global health action |
Spatial QRS-T Angle and Cognitive Decline in Older Subjects. | Mahinrad S, Ferguson I, Macfarlane PW, Clark EN, Stott DJ, Ford I, Mooijaart SP, Trompet S, van Heemst D, Jukema JW, Sabayan B | 2019-01-01 | Cardiac dysfunction, cognitive function, old age, spatial QRS-T angle | Journal of Alzheimer's disease : JAD |
Vital signs and impaired cognition in older emergency department patients: The APOP study. | Lucke JA, de Gelder J, Blomaard LC, Heringhaus C, Alsma J, Klein Nagelvoort Schuit SCE, Brink A, Anten S, Blauw GJ, de Groot B, Mooijaart SP | 2019-01-01 | PloS one | |
Repeat length variations in ATXN1 and AR modify disease expression in Alzheimer’s disease. | Gardiner SL, Harder AVE, Campman YJM, Trompet S, Gussekloo J, van Belzen MJ, Boogaard MW, Roos RAC, Jansen IE, Pijnenburg YAL, Scheltens P, van der Flier WM, Aziz NA | 2019-01-01 | Alzheimer's disease, CAG repeat polymorphisms, Huntington disease, Missing heritability, Polyglutamine diseases | Neurobiology of aging |
Changes in patient satisfaction related to their perceived health state during implementation of improved integrated care for older persons. | Poot AJ, Wopereis DM, den Elzen WPJ, Gussekloo J, Blom JW | 2019-01-01 | PloS one | |
Are serum autoantibodies associated with brain changes in systemic lupus erythematosus? MRI data from the Leiden NP-SLE cohort. | Magro-Checa C, Kumar S, Ramiro S, Beaart-van de Voorde LJ, Eikenboom J, Ronen I, de Bresser J, van Buchem MA, Huizinga TW, Steup-Beekman GM | 2019-01-01 | NP-SLE, Systemic lupus erythematosus, antibodies, cardiovascular risk, magnetic resonance imaging, neuropsychiatric systemic lupus erythematosus, pathogenesis | Lupus |
The Clinical Phenotype of Vascular Cognitive Impairment in Patients with Type 2 Diabetes Mellitus. | Groeneveld ON, Moneti C, Heinen R, de Bresser J, Kuijf HJ, Exalto LG, Boomsma JMF, Kappelle LJ, Barkhof F, Prins ND, Scheltens P, van der Flier WM, Biessels GJ | 2019-01-01 | Cerebrospinal fluid, magnetic resonance imaging, prognosis, type 2 diabetes mellitus, vascular brain injury | Journal of Alzheimer's disease : JAD |
How Do Different Forms of Vascular Brain Injury Relate to Cognition in a Memory Clinic Population: The TRACE-VCI Study. | Boomsma JMF, Exalto LG, Barkhof F, van den Berg E, de Bresser J, Heinen R, Leeuwis AE, Prins ND, Scheltens P, Weinstein HC, van der Flier WM, Biessels GJ | 2019-01-01 | Cerebral small vessel diseases, cerebrovascular disorders, cognitive disorders, neuropsychological test | Journal of Alzheimer's disease : JAD |
Cerebral microbleeds are not associated with postoperative delirium and postoperative cognitive dysfunction in older individuals. | Lachmann G, Kant I, Lammers F, Windmann V, Spies C, Speidel S, Borchers F, Hadzidiakos D, Hendrikse J, Winterer G, de Bresser J | 2019-01-01 | PloS one | |
Opioid Prescription Use in Nursing Home Residents with Advanced Dementia. | Griffioen C, Husebo BS, Flo E, Caljouw MAA, Achterberg WP | 2019-01-01 | Pain medicine (Malden, Mass.) | |
Pain in patients with chronic obstructive pulmonary disease indicated for post-acute pulmonary rehabilitation. | van Dam van Isselt EF, Groenewegen-Sipkema KH, van Eijk M, Chavannes NH, Achterberg WP | 2019-01-01 | Pain, brief pain inventory, health status, symptom burden, unstable COPD | Chronic respiratory disease |
Reliability and usability of a weighted version of the Functional Comorbidity Index. | Kabboord AD, van Eijk M, van Dingenen L, Wouters M, Koet M, van Balen R, Achterberg WP | 2019-01-01 | disease impact, function, multimorbidity, older patients, personalized medicine | Clinical interventions in aging |
Challenging rehabilitation environment for older patients. | Tijsen LM, Derksen EW, Achterberg WP, Buijck BI | 2019-01-01 | aging, care process, geriatric rehabilitation, postacute care | Clinical interventions in aging |
Blood Metabolomic Measures Associate With Present and Future Glycemic Control in Type 2 Diabetes. | 't Hart LM, Vogelzangs N, Mook-Kanamori DO, Brahimaj A, Nano J, van der Heijden AAWA, Willems van Dijk K, Slieker RC, Steyerberg EW, Ikram MA, Beekman M, Boomsma DI, van Duijn CM, Slagboom PE, Stehouwer CDA, Schalkwijk CG, Arts ICW, Dekker JM, Dehghan A, Muka T, van der Kallen CJH, Nijpels G, van Greevenbroek MMJ | 2018-12-01 | The Journal of clinical endocrinology and metabolism | |
Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults. | Parmar P, Lowry E, Cugliari G, Suderman M, Wilson R, Karhunen V, Andrew T, Wiklund P, Wielscher M, Guarrera S, Teumer A, Lehne B, Milani L, de Klein N, Mishra PP, Melton PE, Mandaviya PR, Kasela S, Nano J, Zhang W, Zhang Y, Uitterlinden AG, Peters A, Schöttker B, Gieger C, Anderson D, Boomsma DI, Grabe HJ, Panico S, Veldink JH, van Meurs JBJ, van den Berg L, Beilin LJ, Franke L, Loh M, van Greevenbroek MMJ, Nauck M, Kähönen M, Hurme MA, Raitakari OT, Franco OH, Slagboom PE, van der Harst P, Kunze S, Felix SB, Zhang T, Chen W, Mori TA, Bonnefond A, Heijmans BT, Muka T, Kooner JS, Fischer K, Waldenberger M, Froguel P, Huang RC, Lehtimäki T, Rathmann W, Relton CL, Matullo G, Brenner H, Verweij N, Li S, Chambers JC, Järvelin MR, Sebert S | 2018-12-01 | EBioMedicine | |
Facilitators for maternity waiting home utilisation at Attat Hospital: a mixed-methods study based on 45 years of experience. | Vermeiden T, Schiffer R, Langhorst J, Klappe N, Asera W, Getnet G, Stekelenburg J, van den Akker T | 2018-12-01 | Ethiopia, Ethiopie, communauté, community, community health services, foyers d'attente pour la maternité, health education, hospitals, hôpital, maternal health, maternity waiting homes, santé maternelle, services de santé communautaires, éducation à la santé | Tropical medicine & international health : TM & IH |
Cognitive functioning and structural brain abnormalities in people with Type 2 diabetes mellitus. | Mankovsky B, Zherdova N, van den Berg E, Biessels GJ, de Bresser J | 2018-12-01 | Diabetic medicine : a journal of the British Diabetic Association | |
Screening for malnutrition in patients admitted to the hospital with a proximal femoral fracture. | van der Sijp MPL, van Eijk M, Krijnen P, Schipper IB, Achterberg WP, Niggebrugge AHP | 2018-12-01 | ESPEN, Elderly, Hip fracture, MNA-SF, Malnourishment, Malnutrition, Older patients, Proximal femoral fracture, SNAQ, Screening | Injury |
Quality of life and paracetamol in advanced dementia (Q-PID): protocol of a randomised double-blind placebo-controlled crossover trial. | van Dam PH, Achterberg WP, Gussekloo J, Husebo BS, Caljouw MAA | 2018-11-14 | Dementia, Nursing home, Paracetamol, QUALIDEM, Quality of life | BMC geriatrics |
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. | Ligthart S, Vaez A, Võsa U, Stathopoulou MG, de Vries PS, Prins BP, Van der Most PJ, Tanaka T, Naderi E, Rose LM, Wu Y, Karlsson R, Barbalic M, Lin H, Pool R, Zhu G, Macé A, Sidore C, Trompet S, Mangino M, Sabater-Lleal M, Kemp JP, Abbasi A, Kacprowski T, Verweij N, Smith AV, Huang T, Marzi C, Feitosa MF, Lohman KK, Kleber ME, Milaneschi Y, Mueller C, Huq M, Vlachopoulou E, Lyytikäinen LP, Oldmeadow C, Deelen J, Perola M, Zhao JH, Feenstra B, Amini M, Lahti J, Schraut KE, Fornage M, Suktitipat B, Chen WM, Li X, Nutile T, Malerba G, Luan J, Bak T, Schork N, Del Greco M F, Thiering E, Mahajan A, Marioni RE, Mihailov E, Eriksson J, Ozel AB, Zhang W, Nethander M, Cheng YC, Aslibekyan S, Ang W, Gandin I, Yengo L, Portas L, Kooperberg C, Hofer E, Rajan KB, Schurmann C, den Hollander W, Ahluwalia TS, Zhao J, Draisma HHM, Ford I, Timpson N, Teumer A, Huang H, Wahl S, Liu Y, Huang J, Uh HW, Geller F, Joshi PK, Yanek LR, Trabetti E, Lehne B, Vozzi D, Verbanck M, Biino G, Saba Y, Meulenbelt I, O'Connell JR, Laakso M, Giulianini F, Magnusson PKE, Ballantyne CM, Hottenga JJ, Montgomery GW, Rivadineira F, Rueedi R, Steri M, Herzig KH, Stott DJ, Menni C, Frånberg M, St Pourcain B, Felix SB, Pers TH, Bakker SJL, Kraft P, Peters A, Vaidya D, Delgado G, Smit JH, Großmann V, Sinisalo J, Seppälä I, Williams SR, Holliday EG, Moed M, Langenberg C, Räikkönen K, Ding J, Campbell H, Sale MM, Chen YI, James AL, Ruggiero D, Soranzo N, Hartman CA, Smith EN, Berenson GS, Fuchsberger C, Hernandez D, Tiesler CMT, Giedraitis V, Liewald D, Fischer K, Mellström D, Larsson A, Wang Y, Scott WR, Lorentzon M, Beilby J, Ryan KA, Pennell CE, Vuckovic D, Balkau B, Concas MP, Schmidt R, Mendes de Leon CF, Bottinger EP, Kloppenburg M, Paternoster L, Boehnke M, Musk AW, Willemsen G, Evans DM, Madden PAF, Kähönen M, Kutalik Z, Zoledziewska M, Karhunen V, Kritchevsky SB, Sattar N, Lachance G, Clarke R, Harris TB, Raitakari OT, Attia JR, van Heemst D, Kajantie E, Sorice R, Gambaro G, Scott RA, Hicks AA, Ferrucci L, Standl M, Lindgren CM, Starr JM, Karlsson M, Lind L, Li JZ, Chambers JC, Mori TA, de Geus EJCN, Heath AC, Martin NG, Auvinen J, Buckley BM, de Craen AJM, Waldenberger M, Strauch K, Meitinger T, Scott RJ, McEvoy M, Beekman M, Bombieri C, Ridker PM, Mohlke KL, Pedersen NL, Morrison AC, Boomsma DI, Whitfield JB, Strachan DP, Hofman A, Vollenweider P, Cucca F, Jarvelin MR, Jukema JW, Spector TD, Hamsten A, Zeller T, Uitterlinden AG, Nauck M, Gudnason V, Qi L, Grallert H, Borecki IB, Rotter JI, März W, Wild PS, Lokki ML, Boyle M, Salomaa V, Melbye M, Eriksson JG, Wilson JF, Penninx BWJH, Becker DM, Worrall BB, Gibson G, Krauss RM, Ciullo M, Zaza G, Wareham NJ, Oldehinkel AJ, Palmer LJ, Murray SS, Pramstaller PP, Bandinelli S, Heinrich J, Ingelsson E, Deary IJ, Mägi R, Vandenput L, van der Harst P, Desch KC, Kooner JS, Ohlsson C, Hayward C, Lehtimäki T, Shuldiner AR, Arnett DK, Beilin LJ, Robino A, Froguel P, Pirastu M, Jess T, Koenig W, Loos RJF, Evans DA, Schmidt H, Smith GD, Slagboom PE, Eiriksdottir G, Morris AP, Psaty BM, Tracy RP, Nolte IM, Boerwinkle E, Visvikis-Siest S, Reiner AP, Gross M, Bis JC, Franke L, Franco OH, Benjamin EJ, Chasman DI, Dupuis J, Snieder H, Dehghan A, Alizadeh BZ | 2018-11-01 | C-reactive protein, DEPICT, Mendelian randomization, coronary artery disease, genome-wide association study, inflammation, inflammatory disorders, schizophrenia, system biology | American journal of human genetics |
Functional and cognitive impairment, social functioning, frailty and adverse health outcomes in older patients with esophageal cancer, a systematic review. | van Deudekom FJ, Klop HG, Hartgrink HH, Boonstra JJ, Lips IM, Slingerland M, Mooijaart SP | 2018-11-01 | Cognitive impairment, Esophageal cancer, Frailty, Functional impairment, Geriatric assessment, Older patients, Social status | Journal of geriatric oncology |
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation. | Teumer A, Chaker L, Groeneweg S, Li Y, Di Munno C, Barbieri C, Schultheiss UT, Traglia M, Ahluwalia TS, Akiyama M, Appel EVR, Arking DE, Arnold A, Astrup A, Beekman M, Beilby JP, Bekaert S, Boerwinkle E, Brown SJ, De Buyzere M, Campbell PJ, Ceresini G, Cerqueira C, Cucca F, Deary IJ, Deelen J, Eckardt KU, Ekici AB, Eriksson JG, Ferrrucci L, Fiers T, Fiorillo E, Ford I, Fox CS, Fuchsberger C, Galesloot TE, Gieger C, Gögele M, De Grandi A, Grarup N, Greiser KH, Haljas K, Hansen T, Harris SE, van Heemst D, den Heijer M, Hicks AA, den Hollander W, Homuth G, Hui J, Ikram MA, Ittermann T, Jensen RA, Jing J, Jukema JW, Kajantie E, Kamatani Y, Kasbohm E, Kaufman JM, Kiemeney LA, Kloppenburg M, Kronenberg F, Kubo M, Lahti J, Lapauw B, Li S, Liewald DCM, Lim EM, Linneberg A, Marina M, Mascalzoni D, Matsuda K, Medenwald D, Meisinger C, Meulenbelt I, De Meyer T, Meyer Zu Schwabedissen HE, Mikolajczyk R, Moed M, Netea-Maier RT, Nolte IM, Okada Y, Pala M, Pattaro C, Pedersen O, Petersmann A, Porcu E, Postmus I, Pramstaller PP, Psaty BM, Ramos YFM, Rawal R, Redmond P, Richards JB, Rietzschel ER, Rivadeneira F, Roef G, Rotter JI, Sala CF, Schlessinger D, Selvin E, Slagboom PE, Soranzo N, Sørensen TIA, Spector TD, Starr JM, Stott DJ, Taes Y, Taliun D, Tanaka T, Thuesen B, Tiller D, Toniolo D, Uitterlinden AG, Visser WE, Walsh JP, Wilson SG, Wolffenbuttel BHR, Yang Q, Zheng HF, Cappola A, Peeters RP, Naitza S, Völzke H, Sanna S, Köttgen A, Visser TJ, Medici M | 2018-10-26 | Nature communications | |
The “more at home with dementia” program: a randomized controlled study protocol to determine how caregiver training affects the well-being of patients and caregivers. | Birkenhäger-Gillesse EG, Kollen BJ, Zuidema SU, Achterberg WP | 2018-10-22 | Caregiver, Dementia, Psychosocial intervention, Training | BMC geriatrics |
Effects of the Namaste Care Family programme on quality of life of nursing home residents with advanced dementia and on family caregiving experiences: study protocol of a cluster-randomised controlled trial. | Smaling HJA, Joling KJ, van de Ven PM, Bosmans JE, Simard J, Volicer L, Achterberg WP, Francke AL, van der Steen JT | 2018-10-15 | cluster randomized control trial, dementia, family caregivers, namaste care, palliative care, quality of life | BMJ open |
How general practitioners would deprescribe in frail oldest-old with polypharmacy – the LESS study. | Mantelli S, Jungo KT, Rozsnyai Z, Reeve E, Luymes CH, Poortvliet RKE, Chiolero A, Rodondi N, Gussekloo J, Streit S | 2018-10-12 | Complexity, Deprescribing, Frailty, Multimorbidity, Old age, Polypharmacy | BMC family practice |
Association between fluid management and dilutional coagulopathy in severe postpartum haemorrhage: a nationwide retrospective cohort study. | Gillissen A, van den Akker T, Caram-Deelder C, Henriquez DDCA, Bloemenkamp KWM, van Roosmalen JJM, Eikenboom J, van der Bom JG | 2018-10-11 | Coagulation parameters, Dilutional coagulopathy, Fluid management, Postpartum haemorrhage | BMC pregnancy and childbirth |
Coagulation parameters during the course of severe postpartum hemorrhage: a nationwide retrospective cohort study. | Gillissen A, van den Akker T, Caram-Deelder C, Henriquez DDCA, Bloemenkamp KWM, de Maat MPM, van Roosmalen JJM, Zwart JJ, Eikenboom J, van der Bom JG | 2018-10-09 | Blood advances | |
Association of Thyroid Hormone Therapy With Quality of Life and Thyroid-Related Symptoms in Patients With Subclinical Hypothyroidism: A Systematic Review and Meta-analysis. | Feller M, Snel M, Moutzouri E, Bauer DC, de Montmollin M, Aujesky D, Ford I, Gussekloo J, Kearney PM, Mooijaart S, Quinn T, Stott D, Westendorp R, Rodondi N, Dekkers OM | 2018-10-02 | JAMA | |
A characterization of postzygotic mutations identified in monozygotic twins. | Ouwens KG, Jansen R, Tolhuis B, Slagboom PE, Penninx BWJH, Boomsma DI | 2018-10-01 | genetics, mutations, next-generation sequencing, postzygotic mutations, somatic mosaicism | Human mutation |
Habitual Sleep Measures are Associated with Overall Body Fat, and not Specifically with Visceral Fat, in Men and Women. | Dekker SA, Noordam R, Biermasz NR, de Roos A, Lamb HJ, Rosendaal FR, Rensen PCN, van Heemst D, de Mutsert R | 2018-10-01 | Obesity (Silver Spring, Md.) | |
Maternal mortality after cesarean section in the Netherlands. | Kallianidis AF, Schutte JM, van Roosmalen J, van den Akker T | 2018-10-01 | Cesarean section, High-risk pregnancy, Maternal mortality, Obstetrics, The Netherlands | European journal of obstetrics, gynecology, and reproductive biology |
End-of-life care in the Dutch medical curricula. | de Bruin J, Verhoef MJ, Slaets JPJ, van Bodegom D | 2018-10-01 | End-of-life care, Medical education, National blueprint | Perspectives on medical education |
The Relation Between Thyroid Function and Anemia: A Pooled Analysis of Individual Participant Data. | Wopereis DM, Du Puy RS, van Heemst D, Walsh JP, Bremner A, Bakker SJL, Bauer DC, Cappola AR, Ceresini G, Degryse J, Dullaart RPF, Feller M, Ferrucci L, Floriani C, Franco OH, Iacoviello M, Iervasi G, Imaizumi M, Jukema JW, Khaw KT, Luben RN, Molinaro S, Nauck M, Patel KV, Peeters RP, Psaty BM, Razvi S, Schindhelm RK, van Schoor NM, Stott DJ, Vaes B, Vanderpump MPJ, Völzke H, Westendorp RGJ, Rodondi N, Cobbaert CM, Gussekloo J, den Elzen WPJ | 2018-10-01 | The Journal of clinical endocrinology and metabolism | |
The association between brain volume, cortical brain infarcts, and physical frailty. | Kant IMJ, de Bresser J, van Montfort SJT, Aarts E, Verlaan JJ, Zacharias N, Winterer G, Spies C, Slooter AJC, Hendrikse J | 2018-10-01 | Aging, Magnetic resonance imaging, Neurodegenerative brain changes, Neurovascular brain changes, Physical frailty | Neurobiology of aging |
Study protocol: a randomised controlled trial on the clinical effects of levothyroxine treatment for subclinical hypothyroidism in people aged 80 years and over. | Du Puy RS, Postmus I, Stott DJ, Blum MR, Poortvliet RKE, Den Elzen WPJ, Peeters RP, van Munster BC, Wolffenbuttel BHR, Westendorp RGJ, Kearney PM, Ford I, Kean S, Messow CM, Watt T, Jukema JW, Dekkers OM, Smit JWA, Rodondi N, Gussekloo J, Mooijaart SP | 2018-09-19 | 80-plus, Levothyroxine, Quality of life, Randomised controlled trial, Subclinical hypothyroidism | BMC endocrine disorders |
An Internet-based Acceptance and Commitment Therapy intervention for older adults with anxiety complaints: study protocol for a cluster randomized controlled trial. | Witlox M, Kraaij V, Garnefski N, de Waal MWM, Smit F, Hoencamp E, Gussekloo J, Bohlmeijer ET, Spinhoven P | 2018-09-17 | Acceptance and commitment therapy, Anxiety, Anxiety complaints, Blended care, Internet, Older adults, Randomized controlled trial, Subclinical anxiety | Trials |
Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation. | Luijk R, Wu H, Ward-Caviness CK, Hannon E, Carnero-Montoro E, Min JL, Mandaviya P, Müller-Nurasyid M, Mei H, van der Maarel SM, Relton C, Mill J, Waldenberger M, Bell JT, Jansen R, Zhernakova A, Franke L, 't Hoen PAC, Boomsma DI, van Duijn CM, van Greevenbroek MMJ, Veldink JH, Wijmenga C, van Meurs J, Daxinger L, Slagboom PE, van Zwet EW, Heijmans BT | 2018-09-14 | Nature communications | |
Longevity Around the Turn of the 20th Century: Life-Long Sustained Survival Advantage for Parents of Today’s Nonagenarians. | Berg NVD, Rodríguez-Girondo M, de Craen AJM, Houwing-Duistermaat JJ, Beekman M, Slagboom PE | 2018-09-11 | The journals of gerontology. Series A, Biological sciences and medical sciences | |
Implementation of a Stepwise, Multidisciplinary Intervention for Pain and Challenging Behaviour in Dementia (STA OP!): A Process Evaluation. | Pieper MJC, Achterberg WP, van der Steen JT, Francke AL | 2018-09-07 | Health Plan Implementation, behaviour, dementia, intervention, nursing homes, pain, process evaluation, program evaluation | International journal of integrated care |
Facing up to the global challenges of ageing. | Partridge L, Deelen J, Slagboom PE | 2018-09-01 | Nature | |
Impaired cognition is associated with adverse outcome in older patients in the Emergency Department; the Acutely Presenting Older Patients (APOP) study. | Lucke JA, de Gelder J, Heringhaus C, van der Mast RC, Fogteloo AJ, Anten S, Blauw GJ, de Groot B, Mooijaart SP | 2018-09-01 | Age and ageing | |
Optimization of the APOP screener to predict functional decline or mortality in older emergency department patients: Cross-validation in four prospective cohorts. | de Gelder J, Lucke JA, Blomaard LC, Booijen AM, Fogteloo AJ, Anten S, Steyerberg EW, Alsma J, Klein Nagelvoort Schuit SCE, Brink A, de Groot B, Blauw GJ, Mooijaart SP | 2018-09-01 | Adverse outcomes, Emergency medical services, Older patients, Optimization, Screening | Experimental gerontology |
Clinical aspects of thyroid function during ageing. | Chaker L, Cappola AR, Mooijaart SP, Peeters RP | 2018-09-01 | The lancet. Diabetes & endocrinology | |
Detection and characterization of small infarcts in the caudate nucleus on 7 Tesla MRI: The SMART-MR study. | Ghaznawi R, de Bresser J, van der Graaf Y, Zwartbol MH, Witkamp TD, Geerlings MI, Hendrikse J | 2018-09-01 | 7 tesla MRI, Brain, cerebral infarcts, cerebrovascular disease, magnetic resonance imaging, small vessel disease | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism |
Assessment Scales for Patients with Advanced Huntington’s Disease: Comparison of the UHDRS and UHDRS-FAP. | Winder JY, Achterberg WP, Marinus J, Gardiner SL, Roos RAC | 2018-09-01 | Huntington's disease, Unified Huntington's Disease Rating Scale, Unified Huntington's Disease Rating Scale‐For Advanced Patients, advanced stage, nursing home | Movement disorders clinical practice |
DREAMeR: Drug use Reconsidered in the Elderly using goal Attainment scales during Medication Review; study protocol of a randomised controlled trial. | Verdoorn S, Kwint HF, Blom J, Gussekloo J, Bouvy ML | 2018-08-24 | Clinical medication review, Elderly, Goal attainment scaling, Pharmacists, Polypharmacy, Primary care, Randomised controlled trial | BMC geriatrics |
Genome-wide identification of directed gene networks using large-scale population genomics data. | Luijk R, Dekkers KF, van Iterson M, Arindrarto W, Claringbould A, Hop P, Boomsma DI, van Duijn CM, van Greevenbroek MMJ, Veldink JH, Wijmenga C, Franke L, 't Hoen PAC, Jansen R, van Meurs J, Mei H, Slagboom PE, Heijmans BT, van Zwet EW | 2018-08-06 | Nature communications | |
Facial Wrinkles in Europeans: A Genome-Wide Association Study. | Hamer MA, Pardo LM, Jacobs LC, Deelen J, Uitterlinden AG, Slagboom E, van Heemst D, Uh HW, Beekman M, Kayser M, Liu F, Gunn DA, Nijsten T | 2018-08-01 | The Journal of investigative dermatology | |
High-sensitivity C-reactive protein, low-grade systemic inflammation and type 2 diabetes mellitus: A two-sample Mendelian randomization study. | Noordam R, Oudt CH, Bos MM, Smit RAJ, van Heemst D | 2018-08-01 | C-reactive protein, Inflammation, Mendelian randomization, Type 2 diabetes mellitus | Nutrition, metabolism, and cardiovascular diseases : NMCD |
Birthing experience and quality of life after vacuum delivery and second-stage caesarean section: a prospective cohort study in Uganda. | Nolens B, van den Akker T, Lule J, Twinomuhangi S, van Roosmalen J, Byamugisha J | 2018-08-01 | birthing experience, caesarean section, césarienne, douleur, dyspareunia, dyspareunie, expérience de l'accouchement, extraction sous vide, pain, quality of life, qualité de vie, vacuum extraction | Tropical medicine & international health : TM & IH |
Impact of Thyroid Hormone Therapy on Atherosclerosis in the Elderly With Subclinical Hypothyroidism: A Randomized Trial. | Blum MR, Gencer B, Adam L, Feller M, Collet TH, da Costa BR, Moutzouri E, Dopheide J, Depairon M, Sykiotis GP, Kearney P, Gussekloo J, Westendorp R, Stott DJ, Bauer DC, Rodondi N | 2018-08-01 | The Journal of clinical endocrinology and metabolism | |
The effectiveness of functional task exercise and physical therapy as prevention of functional decline in community dwelling older people with complex health problems. | Siemonsma PC, Blom JW, Hofstetter H, van Hespen ATH, Gussekloo J, Drewes YM, van Meeteren NLU | 2018-07-17 | Exercise, Functional training, Older people | BMC geriatrics |
Thyroid Stimulating Hormone and Bone Mineral Density: Evidence From a Two-Sample Mendelian Randomization Study and a Candidate Gene Association Study. | van Vliet NA, Noordam R, van Klinken JB, Westendorp RG, Bassett JD, Williams GR, van Heemst D | 2018-07-01 | DXA, GENERAL POPULATION STUDIES, HUMAN ASSOCIATION STUDIES, NEUROENDOCRINE | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research |
Prospective cohort study comparing outcomes between vacuum extraction and second-stage cesarean delivery at a Ugandan tertiary referral hospital. | Nolens B, Namiiro F, Lule J, van den Akker T, van Roosmalen J, Byamugisha J | 2018-07-01 | Cesarean delivery, Instrumental delivery, Maternal morbidity, Maternal mortality, Neonatal morbidity, Perinatal mortality, Vacuum extraction, Ventouse delivery | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics |
Lower blood pressure during antihypertensive treatment is associated with higher all-cause mortality and accelerated cognitive decline in the oldest-old. Data from the Leiden 85-plus Study. | Streit S, Poortvliet RKE, Gussekloo J | 2018-07-01 | antihypertensive treatment, cognitive function, frailty, hypertension, older people, oldest-old | Age and ageing |
Prediction of functional decline in community-dwelling older persons in general practice: a cohort study. | van Blijswijk SCE, Blom JW, de Craen AJM, den Elzen WPJ, Gussekloo J | 2018-06-11 | Community-dwelling older person, Functional decline, General practice, Prediction, Readily available variables | BMC geriatrics |
Change in quality of life after a multidisciplinary intervention for people with dementia: A cluster randomized controlled trial. | Klapwijk MS, Caljouw MAA, Pieper MJC, Putter H, van der Steen JT, Achterberg WP | 2018-06-11 | QUALIDEM, dementia, dementia care, long-term care, nursing home medicine, pain, quality of life | International journal of geriatric psychiatry |
Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies. | van der Lee SJ, Teunissen CE, Pool R, Shipley MJ, Teumer A, Chouraki V, Melo van Lent D, Tynkkynen J, Fischer K, Hernesniemi J, Haller T, Singh-Manoux A, Verhoeven A, Willemsen G, de Leeuw FA, Wagner H, van Dongen J, Hertel J, Budde K, Willems van Dijk K, Weinhold L, Ikram MA, Pietzner M, Perola M, Wagner M, Friedrich N, Slagboom PE, Scheltens P, Yang Q, Gertzen RE, Egert S, Li S, Hankemeier T, van Beijsterveldt CEM, Vasan RS, Maier W, Peeters CFW, Jörgen Grabe H, Ramirez A, Seshadri S, Metspalu A, Kivimäki M, Salomaa V, Demirkan A, Boomsma DI, van der Flier WM, Amin N, van Duijn CM | 2018-06-01 | Alzheimer's disease, Cognitive function, Dementia, General cognitive ability, Lifestyle factors, Metabolites, Metabolomics, NMR | Alzheimer's & dementia : the journal of the Alzheimer's Association |
The Leiden Family Lab study on Social Anxiety Disorder: A multiplex, multigenerational family study on neurocognitive endophenotypes. | Bas-Hoogendam JM, Harrewijn A, Tissier RLM, van der Molen MJW, van Steenbergen H, van Vliet IM, Reichart CG, Houwing-Duistermaat JJ, Slagboom PE, van der Wee NJA, Westenberg PM | 2018-06-01 | EEG, MRI, endophenotypes, family study, social anxiety disorder | International journal of methods in psychiatric research |
Establishing a Twin Register: An Invaluable Resource for (Behavior) Genetic, Epidemiological, Biomarker, and ‘Omics’ Studies. | Odintsova VV, Willemsen G, Dolan CV, Hottenga JJ, Martin NG, Slagboom PE, Ordoñana JR, Boomsma DI | 2018-06-01 | recruitment, twin register, twin research, zygosity determination | Twin research and human genetics : the official journal of the International Society for Twin Studies |
Regional variations in childbirth interventions in the Netherlands: a nationwide explorative study. | Seijmonsbergen-Schermers AE, Zondag DC, Nieuwenhuijze M, Van den Akker T, Verhoeven CJ, Geerts C, Schellevis F, De Jonge A | 2018-06-01 | Caesarean section, Childbirth, Induction, Interventions, Obstetric, Outcomes, Pain relief, Regional, Variations | BMC pregnancy and childbirth |
Regression discontinuity was a valid design for dichotomous outcomes in three randomized trials. | van Leeuwen N, Lingsma HF, Mooijaart SP, Nieboer D, Trompet S, Steyerberg EW | 2018-06-01 | Causal inference, Local logistic regression, Logistic regression, Polynomials, Quasi-experimental trials, Regression discontinuity design, Restricted cubic splines, Trial design | Journal of clinical epidemiology |
The effect of vitamin B12 and folic acid supplementation on routine haematological parameters in older people: an individual participant data meta-analysis. | Smelt AF, Gussekloo J, Bermingham LW, Allen E, Dangour AD, Eussen SJ, Favrat B, De Groot LC, Kok FJ, Kwok T, Mangoni AA, Ntaios G, Van De Rest O, Seal E, Vaucher P, Verhoef P, Stijnen T, Den Elzen WP | 2018-06-01 | European journal of clinical nutrition | |
Perceived doctor-patient relationship and satisfaction with general practitioner care in older persons in residential homes. | de Waard CS, Poot AJ, den Elzen WPJ, Wind AW, Caljouw MAA, Gussekloo J | 2018-06-01 | Doctor-patient relationship, general practitioner, older persons, primary care, residential home, satisfaction | Scandinavian journal of primary health care |
Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception. | Slieker RC, Relton CL, Gaunt TR, Slagboom PE, Heijmans BT | 2018-05-30 | 450 k, Ageing, DNA methylation, Tissue-specific | Epigenetics & chromatin |
Birth preparedness and complication readiness among pregnant women admitted in a rural hospital in Rwanda. | Smeele P, Kalisa R, van Elteren M, van Roosmalen J, van den Akker T | 2018-05-30 | Birth preparedness, Complication readiness, Health promotion, High-risk pregnancy, Obstetrics, Rwanda | BMC pregnancy and childbirth |
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. | Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C, Hofer E, Ikram MA, Karlsson R, Knowles E, Lahti J, Leber M, Li S, Mather KA, Melle I, Morris D, Oldmeadow C, Palviainen T, Payton A, Pazoki R, Petrovic K, Reynolds CA, Sargurupremraj M, Scholz M, Smith JA, Smith AV, Terzikhan N, Thalamuthu A, Trompet S, van der Lee SJ, Ware EB, Windham BG, Wright MJ, Yang J, Yu J, Ames D, Amin N, Amouyel P, Andreassen OA, Armstrong NJ, Assareh AA, Attia JR, Attix D, Avramopoulos D, Bennett DA, Böhmer AC, Boyle PA, Brodaty H, Campbell H, Cannon TD, Cirulli ET, Congdon E, Conley ED, Corley J, Cox SR, Dale AM, Dehghan A, Dick D, Dickinson D, Eriksson JG, Evangelou E, Faul JD, Ford I, Freimer NA, Gao H, Giegling I, Gillespie NA, Gordon SD, Gottesman RF, Griswold ME, Gudnason V, Harris TB, Hartmann AM, Hatzimanolis A, Heiss G, Holliday EG, Joshi PK, Kähönen M, Kardia SLR, Karlsson I, Kleineidam L, Knopman DS, Kochan NA, Konte B, Kwok JB, Le Hellard S, Lee T, Lehtimäki T, Li SC, Lill CM, Liu T, Koini M, London E, Longstreth WT, Lopez OL, Loukola A, Luck T, Lundervold AJ, Lundquist A, Lyytikäinen LP, Martin NG, Montgomery GW, Murray AD, Need AC, Noordam R, Nyberg L, Ollier W, Papenberg G, Pattie A, Polasek O, Poldrack RA, Psaty BM, Reppermund S, Riedel-Heller SG, Rose RJ, Rotter JI, Roussos P, Rovio SP, Saba Y, Sabb FW, Sachdev PS, Satizabal CL, Schmid M, Scott RJ, Scult MA, Simino J, Slagboom PE, Smyrnis N, Soumaré A, Stefanis NC, Stott DJ, Straub RE, Sundet K, Taylor AM, Taylor KD, Tzoulaki I, Tzourio C, Uitterlinden A, Vitart V, Voineskos AN, Kaprio J, Wagner M, Wagner H, Weinhold L, Wen KH, Widen E, Yang Q, Zhao W, Adams HHH, Arking DE, Bilder RM, Bitsios P, Boerwinkle E, Chiba-Falek O, Corvin A, De Jager PL, Debette S, Donohoe G, Elliott P, Fitzpatrick AL, Gill M, Glahn DC, Hägg S, Hansell NK, Hariri AR, Ikram MK, Jukema JW, Vuoksimaa E, Keller MC, Kremen WS, Launer L, Lindenberger U, Palotie A, Pedersen NL, Pendleton N, Porteous DJ, Räikkönen K, Raitakari OT, Ramirez A, Reinvang I, Rudan I, Dan Rujescu, Schmidt R, Schmidt H, Schofield PW, Schofield PR, Starr JM, Steen VM, Trollor JN, Turner ST, Van Duijn CM, Villringer A, Weinberger DR, Weir DR, Wilson JF, Malhotra A, McIntosh AM, Gale CR, Seshadri S, Mosley TH, Bressler J, Lencz T, Deary IJ | 2018-05-29 | Nature communications | |
A Role for New Brain Magnetic Resonance Imaging Modalities in Daily Clinical Practice: Protocol of the Prediction of Cognitive Recovery After Stroke (PROCRAS) Study. | Aben HP, Reijmer YD, Visser-Meily JM, Spikman JM, de Bresser J, Biessels GJ, de Kort PL | 2018-05-28 | anisotropy, brain infarction, cognitive dysfunction, diffusion magnetic resonance imaging, diffusion tensor imaging, stroke | JMIR research protocols |
Frailty in end-stage hip or knee osteoarthritis: validation of the Groningen Frailty Indicator (GFI) questionnaire. | Meessen JMTA, Leichtenberg CS, Tilbury C, Kaptein BL, Koster LA, Slagboom PE, Verdegaal SHM, Onstenk R, van der Linden-van der Zwaag HMJ, Kaptijn H, Vehmeijer SBW, Marijnissen WC, Damen PJ, Nelissen RGHH, Vliet Vlieland TPM | 2018-05-01 | Arthroplasty, Frailty, Groningen Frailty Indicator, Osteoarthritis, Validation | Rheumatology international |
Stress evokes stronger medial posterior cingulate deactivations during emotional distraction in slower paced aging. | Oei NYL, Jansen SW, Veer IM, Slagboom PE, van de Grond J, van Heemst D | 2018-05-01 | Aging, Cortisol, Emotional distraction, Familial longevity, HPA-axis, Medial posterior cingulate cortex, Social stress | Biological psychology |
CETP (Cholesteryl Ester Transfer Protein) Concentration: A Genome-Wide Association Study Followed by Mendelian Randomization on Coronary Artery Disease. | Blauw LL, Li-Gao R, Noordam R, de Mutsert R, Trompet S, Berbée JFP, Wang Y, van Klinken JB, Christen T, van Heemst D, Mook-Kanamori DO, Rosendaal FR, Jukema JW, Rensen PCN, Willems van Dijk K | 2018-05-01 | cardiovascular diseases, coronary artery disease, lipids | Circulation. Genomic and precision medicine |
Statement on Minimum Standards for the Care of Older People in Emergency Departments by the Geriatric Emergency Medicine Special Interest Group of the International Federation for Emergency Medicine. | Ellis B, Carpenter CR, Lowthian JA, Mooijaart SP, Nickel CH, Melady D | 2018-05-01 | geriatric emergency medicine, international, older people, standards | CJEM |
The Six-Item Cognitive Impairment Test Is Associated with Adverse Outcomes in Acutely Hospitalized Older Patients: A Prospective Cohort Study. | Lucke JA, van der Mast RC, de Gelder J, Heim N, de Groot B, Mooijaart SP, Blauw GJ | 2018-05-01 | Acute care, Cognitive impairment, Functional impairment, Geriatrics, Hospital admission, Hospital length of stay, Mortality, Older patients, Six-Item Cognitive Impairment Test | Dementia and geriatric cognitive disorders extra |
Association of diastolic blood pressure with cardiovascular events in older people varies upon cardiovascular history. | Wijsman LW, Muller M, de Craen AJM, Jukema JW, Westendorp RGJ, Mooijaart SP | 2018-04-01 | Journal of hypertension | |
Nuclear magnetic resonance-based metabolomics identifies phenylalanine as a novel predictor of incident heart failure hospitalisation: results from PROSPER and FINRISK 1997. | Delles C, Rankin NJ, Boachie C, McConnachie A, Ford I, Kangas A, Soininen P, Trompet S, Mooijaart SP, Jukema JW, Zannad F, Ala-Korpela M, Salomaa V, Havulinna AS, Welsh P, Würtz P, Sattar N | 2018-04-01 | Advanced lipoprotein profiling, FINRISK, Heart failure, Metabolomics, PROSPER, Phenylalanine | European journal of heart failure |
Predictors and Outcomes of Revisits in Older Adults Discharged from the Emergency Department. | de Gelder J, Lucke JA, de Groot B, Fogteloo AJ, Anten S, Heringhaus C, Dekkers OM, Blauw GJ, Mooijaart SP | 2018-04-01 | Emergency Department, adverse outcomes, emergency medical services, older patients, revisits | Journal of the American Geriatrics Society |
Drug-related problems identified during medication review before and after the introduction of a clinical decision support system. | Verdoorn S, Kwint HF, Hoogland P, Gussekloo J, Bouvy ML | 2018-04-01 | computerised decision support, elderly, medication, pharmacist consultation, pharmacy practice | Journal of clinical pharmacy and therapeutics |
Unravelling complex primary-care programs to maintain independent living in older people: a systematic overview. | Smit LC, Schuurmans MJ, Blom JW, Fabbricotti IN, Jansen APD, Kempen GIJM, Koopmans R, Looman WM, Melis RJF, Metzelthin SF, Moll van Charante EP, Muntinga ME, Ruikes FGH, Spoorenberg SLW, Suijker JJ, Wynia K, Gussekloo J, De Wit NJ, Bleijenberg N | 2018-04-01 | Complex interventions, Development, Evaluation, Improvement, Primary-care programs, Systematic overview | Journal of clinical epidemiology |
BeCaf study: caffeine and behaviour in nursing homes, a study protocol and EBM training program. | Kromhout MA, van Eijk M, Pieper MJC, Chel VGM, Achterberg WP, Numans ME | 2018-04-01 | The Netherlands journal of medicine | |
A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening. | van den Berg R, Kooijman S, Noordam R, Ramkisoensing A, Abreu-Vieira G, Tambyrajah LL, Dijk W, Ruppert P, Mol IM, Kramar B, Caputo R, Puig LS, de Ruiter EM, Kroon J, Hoekstra M, van der Sluis RJ, Meijer OC, Willems van Dijk K, van Kerkhof LWM, Christodoulides C, Karpe F, Gerhart-Hines Z, Kersten S, Meijer JH, Coomans CP, van Heemst D, Biermasz NR, Rensen PCN | 2018-03-27 | APOE(∗)3-Leiden.CETP mice, angiopoietin-like 4, brown adipose tissue, circadian rhythm, diurnal rhythm, fatty acids, lipoprotein lipase, postprandial lipid response, triglycerides | Cell reports |
Prevalence of potentially inappropriate prescribing in a subpopulation of older European clinical trial participants: a cross-sectional study. | O Riordan D, Aubert CE, Walsh KA, Van Dorland A, Rodondi N, Du Puy RS, Poortvliet RKE, Gussekloo J, Sinnott C, Byrne S, Galvin R, Jukema JW, Mooijaart SP, Baumgartner C, McCarthy V, Walsh EK, Collet TH, Dekkers OM, Blum MR, Kearney PM | 2018-03-22 | primary care | BMJ open |
Visit-to-visit lipid variability: Clinical significance, effects of lipid-lowering treatment, and (pharmaco) genetics. | Smit RAJ, Jukema JW, Postmus I, Ford I, Slagboom PE, Heijmans BT, Le Cessie S, Trompet S | 2018-03-01 | GWAS, Lipoprotein, Pharmacogenetics, Risk factor, Vascular disease, Visit-to-visit variability | Journal of clinical lipidology |
IgG glycosylation and DNA methylation are interconnected with smoking. | Wahl A, Kasela S, Carnero-Montoro E, van Iterson M, Štambuk J, Sharma S, van den Akker E, Klaric L, Benedetti E, Razdorov G, Trbojević-Akmačić I, Vučković F, Ugrina I, Beekman M, Deelen J, van Heemst D, Heijmans BT, B I O S Consortium, Wuhrer M, Plomp R, Keser T, Šimurina M, Pavić T, Gudelj I, Krištić J, Grallert H, Kunze S, Peters A, Bell JT, Spector TD, Milani L, Slagboom PE, Lauc G, Gieger C | 2018-03-01 | DNA methylation, EWAS, IgG glycosylation, Mediation, Smoking | Biochimica et biophysica acta. General subjects |
Vitality club: a proof-of-principle of peer coaching for daily physical activity by older adults. | van de Vijver PL, Wielens H, Slaets JPJ, van Bodegom D | 2018-03-01 | Translational behavioral medicine | |
Burden of cardiovascular disease across 29 countries and GPs’ decision to treat hypertension in oldest-old. | Streit S, Gussekloo J, Burman RA, Collins C, Kitanovska BG, Gintere S, Gómez Bravo R, Hoffmann K, Iftode C, Johansen KL, Kerse N, Koskela TH, Peštić SK, Kurpas D, Mallen CD, Maisonneuve H, Merlo C, Mueller Y, Muth C, Ornelas RH, Šter MP, Petrazzuoli F, Rosemann T, Sattler M, Švadlenková Z, Tatsioni A, Thulesius H, Tkachenko V, Torzsa P, Tsopra R, Tuz C, Verschoor M, Viegas RPA, Vinker S, de Waal MWM, Zeller A, Rodondi N, Poortvliet RKE | 2018-03-01 | Oldest-old, cardiovascular disease burden, clinical decision-making, hypertension, life expectancy | Scandinavian journal of primary health care |
Long-term restrictions in participation in stroke survivors under and over 70 years of age. | de Graaf JA, van Mierlo ML, Post MWM, Achterberg WP, Kappelle LJ, Visser-Meily JMA | 2018-03-01 | CVA, USER-P, elderly, emotional functioning, predictors, restore4stroke | Disability and rehabilitation |
Effects on pain of a stepwise multidisciplinary intervention (STA OP!) that targets pain and behavior in advanced dementia: A cluster randomized controlled trial. | Pieper MJC, van der Steen JT, Francke AL, Scherder EJA, Twisk JWR, Achterberg WP | 2018-03-01 | Pain, dementia, nursing homes, pain management, randomized controlled trial | Palliative medicine |
Effects of two feedback interventions on end-of-life outcomes in nursing home residents with dementia: A cluster-randomized controlled three-armed trial. | Boogaard JA, de Vet HCW, van Soest-Poortvliet MC, Anema JR, Achterberg WP, van der Steen JT | 2018-03-01 | Palliative care, dementia, nursing homes, quality improvement, quality of health care | Palliative medicine |
Effects of Psychosocial Interventions for Behavioral and Psychological Symptoms in Dementia on the Prescription of Psychotropic Drugs: A Systematic Review and Meta-Analyses. | Birkenhäger-Gillesse EG, Kollen BJ, Achterberg WP, Boersma F, Jongman L, Zuidema SU | 2018-03-01 | Nursing homes, antipsychotics, dementia, psychosocial intervention, psychotropic drugs, systematic review | Journal of the American Medical Directors Association |
Do senescence markers correlate in vitro and in situ within individual human donors? | Waaijer MEC, Gunn DA, van Heemst D, Slagboom PE, Sedivy JM, Dirks RW, Tanke HJ, Westendorp RGJ, Maier AB | 2018-02-28 | cellular senescence, correlation, in situ, in vitro, markers | Aging |
Laparotomy in women with severe acute maternal morbidity: secondary analysis of a nationwide cohort study. | Witteveen T, Kallianidis A, Zwart JJ, Bloemenkamp KW, van Roosmalen J, van den Akker T | 2018-02-27 | Cesarean section, Childbirth, Cohort studies, High-risk pregnancy, Laparotomy, Maternal mortality, Obstetric surgical procedures, Obstetrics, Severe acute maternal morbidity | BMC pregnancy and childbirth |
Interrelationship of the rs7903146 TCF7L2 gene variant with measures of glucose metabolism and adiposity: The NEO study. | Noordam R, Zwetsloot CPA, de Mutsert R, Mook-Kanamori DO, Lamb HJ, de Roos A, de Koning EJP, Rosendaal FR, Willems van Dijk K, van Heemst D | 2018-02-01 | Adiposity, Diabetes, Glucose, Insulin, TCF7L2 | Nutrition, metabolism, and cardiovascular diseases : NMCD |
Association of complement receptor 1 gene polymorphisms with cognitive function. | Zijlstra LE, Jukema JW, Mooijaart SP, de Vries MA, Stott DJ, Castro Cabezas M, Trompet S | 2018-02-01 | Alzheimer’s disease, chromosome 1, cognitive function, complement receptor 1, older patients | Physiological genomics |
White matter hyperintensity shape and location feature analysis on brain MRI; proof of principle study in patients with diabetes. | de Bresser J, Kuijf HJ, Zaanen K, Viergever MA, Hendrikse J, Biessels GJ | 2018-01-30 | Scientific reports | |
A SNP panel for identification of DNA and RNA specimens. | Yousefi S, Abbassi-Daloii T, Kraaijenbrink T, Vermaat M, Mei H, van 't Hof P, van Iterson M, Zhernakova DV, Claringbould A, Franke L, 't Hart LM, Slieker RC, van der Heijden A, de Knijff P, 't Hoen PAC | 2018-01-25 | Biobanking, Forensics, Genetic variation, Mix up samples, Sample tracking | BMC genomics |
Medical and moral considerations regarding complex medical decisions in older patients with multimorbidity: a compact deliberation framework. | Janssens JFAM, de Kort SJ, Achterberg WP, Kurrle S, Kerse N, Cameron ID, Touwen DP | 2018-01-25 | Elderly, Intercurrent disease, Medical decision, Multimorbidity, Shared decision making | BMC geriatrics |
Factors associated with intended use of a maternity waiting home in Southern Ethiopia: a community-based cross-sectional study. | Vermeiden T, Braat F, Medhin G, Gaym A, van den Akker T, Stekelenburg J | 2018-01-19 | Ethiopia, Health-seeking behaviour, Maternal health, Maternal mortality, Maternity waiting homes, Obstetrics | BMC pregnancy and childbirth |
Variations in childbirth interventions in high-income countries: protocol for a multinational cross-sectional study. | Seijmonsbergen-Schermers A, van den Akker T, Beeckman K, Bogaerts A, Barros M, Janssen P, Binfa L, Rydahl E, Frith L, Gross MM, Hálfdánsdóttir B, Daly D, Calleja-Agius J, Gillen P, Vika Nilsen AB, Declercq E, de Jonge A | 2018-01-10 | caesarean section, childbirth interventions, episiotomy, instrumental delivery, international variations, maternal and perinatal outcmes | BMJ open |
Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group. | Floyd JS, Sitlani CM, Avery CL, Noordam R, Li X, Smith AV, Gogarten SM, Li J, Broer L, Evans DS, Trompet S, Brody JA, Stewart JD, Eicher JD, Seyerle AA, Roach J, Lange LA, Lin HJ, Kors JA, Harris TB, Li-Gao R, Sattar N, Cummings SR, Wiggins KL, Napier MD, Stürmer T, Bis JC, Kerr KF, Uitterlinden AG, Taylor KD, Stott DJ, de Mutsert R, Launer LJ, Busch EL, Méndez-Giráldez R, Sotoodehnia N, Soliman EZ, Li Y, Duan Q, Rosendaal FR, Slagboom PE, Wilhelmsen KC, Reiner AP, Chen YD, Heckbert SR, Kaplan RC, Rice KM, Jukema JW, Johnson AD, Liu Y, Mook-Kanamori DO, Gudnason V, Wilson JG, Rotter JI, Laurie CC, Psaty BM, Whitsel EA, Cupples LA, Stricker BH | 2018-01-01 | The pharmacogenomics journal | |
DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood. | Tobi EW, Slieker RC, Luijk R, Dekkers KF, Stein AD, Xu KM, Slagboom PE, van Zwet EW, Lumey LH, Heijmans BT | 2018-01-01 | Science advances | |
Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study. | Molnos S, Wahl S, Haid M, Eekhoff EMW, Pool R, Floegel A, Deelen J, Much D, Prehn C, Breier M, Draisma HH, van Leeuwen N, Simonis-Bik AMC, Jonsson A, Willemsen G, Bernigau W, Wang-Sattler R, Suhre K, Peters A, Thorand B, Herder C, Rathmann W, Roden M, Gieger C, Kramer MHH, van Heemst D, Pedersen HK, Gudmundsdottir V, Schulze MB, Pischon T, de Geus EJC, Boeing H, Boomsma DI, Ziegler AG, Slagboom PE, Hummel S, Beekman M, Grallert H, Brunak S, McCarthy MI, Gupta R, Pearson ER, Adamski J, 't Hart LM | 2018-01-01 | Epidemiology, Insulin secretion, Metabolomics, Prediction of diabetes, Type 2 diabetes | Diabetologia |
Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns. | Wahl A, van den Akker E, Klaric L, Štambuk J, Benedetti E, Plomp R, Razdorov G, Trbojević-Akmačić I, Deelen J, van Heemst D, Slagboom PE, Vučković F, Grallert H, Krumsiek J, Strauch K, Peters A, Meitinger T, Hayward C, Wuhrer M, Beekman M, Lauc G, Gieger C | 2018-01-01 | LC–ESI-MS, RUNX3, genome-wide association study, glycosylation, immunoglobulin G | Frontiers in immunology |
Natriuretic Peptides in Post-mortem Brain Tissue and Cerebrospinal Fluid of Non-demented Humans and Alzheimer’s Disease Patients. | Mahinrad S, Bulk M, van der Velpen I, Mahfouz A, van Roon-Mom W, Fedarko N, Yasar S, Sabayan B, van Heemst D, van der Weerd L | 2018-01-01 | Alzheimer disease, brain, cerebrospinal fluid, gene expression, humans, natriuretic peptides | Frontiers in neuroscience |
DNA methylation signatures of educational attainment. | van Dongen J, Bonder MJ, Dekkers KF, Nivard MG, van Iterson M, Willemsen G, Beekman M, van der Spek A, van Meurs JBJ, Franke L, Heijmans BT, van Duijn CM, Slagboom PE, Boomsma DI | 2018-01-01 | NPJ science of learning | |
Comparison of pregnancy outcomes between maternity waiting home users and non-users at hospitals with and without a maternity waiting home: retrospective cohort study. | Braat F, Vermeiden T, Getnet G, Schiffer R, van den Akker T, Stekelenburg J | 2018-01-01 | International health | |
Facilitators and barriers to birth preparedness and complication readiness in rural Rwanda among community health workers and community members: a qualitative study. | Kalisa R, Smeele P, van Elteren M, van den Akker T, van Roosmalen J | 2018-01-01 | Perceptions, Pregnancy, facility delivery, birth preparedness, Respectful maternity care | Maternal health, neonatology and perinatology |
Severe maternal outcomes in eastern Ethiopia: Application of the adapted maternal near miss tool. | Tura AK, Zwart J, van Roosmalen J, Stekelenburg J, van den Akker T, Scherjon S | 2018-01-01 | PloS one | |
Early prediction of hospital admission for emergency department patients: a comparison between patients younger or older than 70 years. | Lucke JA, de Gelder J, Clarijs F, Heringhaus C, de Craen AJM, Fogteloo AJ, Blauw GJ, Groot B, Mooijaart SP | 2018-01-01 | aged, emergency department, epidemiology., geriatrics, hospitalizations, research | Emergency medicine journal : EMJ |
High Adiposity Is Associated With Higher Nocturnal and Diurnal Glycaemia, but Not With Glycemic Variability in Older Individuals Without Diabetes. | Noordam R, Huurman NC, Wijsman CA, Akintola AA, Jansen SWM, Stassen S, Beekman M, van de Rest O, Slagboom PE, Mooijaart SP, van Heemst D | 2018-01-01 | adiposity, body composition, continuous glucose monitoring, glycemia, glycemic variability | Frontiers in endocrinology |
Association between subclinical thyroid dysfunction and change in bone mineral density in prospective cohorts. | Segna D, Bauer DC, Feller M, Schneider C, Fink HA, Aubert CE, Collet TH, da Costa BR, Fischer K, Peeters RP, Cappola AR, Blum MR, van Dorland HA, Robbins J, Naylor K, Eastell R, Uitterlinden AG, Rivadeneira Ramirez F, Gogakos A, Gussekloo J, Williams GR, Schwartz A, Cauley JA, Aujesky DA, Bischoff-Ferrari HA, Rodondi N | 2018-01-01 | bone density, bone loss, hyperthyroidism, hypothyroidism, prospective studies, thyroid disease | Journal of internal medicine |
Wishes and needs of community-dwelling older persons concerning general practice: A qualitative study. | van Blijswijk SCE, de Waard CS, van Peet PG, Keizer D, von Faber M, de Waal MWM, den Elzen WPJ, Gussekloo J, Blom JW | 2018-01-01 | PloS one | |
Evaluation of a deep learning approach for the segmentation of brain tissues and white matter hyperintensities of presumed vascular origin in MRI. | Moeskops P, de Bresser J, Kuijf HJ, Mendrik AM, Biessels GJ, Pluim JPW, Išgum I | 2018-01-01 | Brain MRI, Brain atrophy, Convolutional neural networks, Deep learning, Motion artefacts, Segmentation, White matter hyperintensities | NeuroImage. Clinical |
Fast CSF MRI for brain segmentation; Cross-validation by comparison with 3D T1-based brain segmentation methods. | van der Kleij LA, de Bresser J, Hendrikse J, Siero JCW, Petersen ET, De Vis JB | 2018-01-01 | PloS one | |
The cumulative effect of small vessel disease lesions is reflected in structural brain networks of memory clinic patients. | Heinen R, Vlegels N, de Bresser J, Leemans A, Biessels GJ, Reijmer YD | 2018-01-01 | Cerebral small vessel disease, Cognition, Diffusion-weighted imaging, Magnetic resonance imaging, Vascular cognitive impairment | NeuroImage. Clinical |
Parietal Involvement in Constructional Apraxia as Measured Using the Pentagon Copying Task. | Van der Stigchel S, de Bresser J, Heinen R, Koek HL, Reijmer YD, Biessels GJ, van den Berg E | 2018-01-01 | Constructional apraxia, Neurodegenerative disease, Visual attention | Dementia and geriatric cognitive disorders |
Pain Assessment in Impaired Cognition (PAIC): content validity of the Dutch version of a new and universal tool to measure pain in dementia. | van Dalen-Kok AH, Achterberg WP, Rijkmans WE, Tukker-van Vuuren SA, Delwel S, de Vet HC, Lobbezoo F, de Waal MW | 2018-01-01 | content validity, dementia, education, nursing home, observational pain measurement tool, pain | Clinical interventions in aging |
[Death after a fall in patients with advanced dementia: cause of death natural or unnatural?]. | van Dingenen ECM, van Eijk M, Chel VGM, Engberts DP, Achterberg WP | 2018-01-01 | Nederlands tijdschrift voor geneeskunde | |
Comorbidity and intercurrent diseases in geriatric stroke rehabilitation: a multicentre observational study in skilled nursing facilities. | Kabboord AD, Van Eijk M, Buijck BI, Koopmans RTCM, van Balen R, Achterberg WP | 2018-01-01 | Comorbidity, Functional impairments, Geriatric rehabilitation, Intercurrent diseases, Stroke | European geriatric medicine |
Marriage as Protector for Nursing Home Admission in Huntington’s Disease. | Winder JY, Achterberg WP, Roos RAC | 2018-01-01 | Huntington’s disease, advanced stage, functional assessment, marriage, nursing home admission | Journal of Huntington's disease |
Geriatric rehabilitation in older patients with cardiovascular disease: a feasibility study. | van Dam van Isselt EF, van Wijngaarden J, Lok DJA, Achterberg WP | 2018-01-01 | Cardiac surgery, Cardiovascular disease, Feasibility, Geriatric rehabilitation, Heart failure | European geriatric medicine |
Adaptation of the WHO maternal near miss tool for use in sub-Saharan Africa: an International Delphi study. | Tura AK, Stekelenburg J, Scherjon SA, Zwart J, van den Akker T, van Roosmalen J, Gordijn SJ | 2017-12-29 | Delphi, Global health, Maternal near miss, Severe maternal morbidity, Sub–Saharan Africa | BMC pregnancy and childbirth |
DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation. | Richard MA, Huan T, Ligthart S, Gondalia R, Jhun MA, Brody JA, Irvin MR, Marioni R, Shen J, Tsai PC, Montasser ME, Jia Y, Syme C, Salfati EL, Boerwinkle E, Guan W, Mosley TH, Bressler J, Morrison AC, Liu C, Mendelson MM, Uitterlinden AG, van Meurs JB, Franco OH, Zhang G, Li Y, Stewart JD, Bis JC, Psaty BM, Chen YI, Kardia SLR, Zhao W, Turner ST, Absher D, Aslibekyan S, Starr JM, McRae AF, Hou L, Just AC, Schwartz JD, Vokonas PS, Menni C, Spector TD, Shuldiner A, Damcott CM, Rotter JI, Palmas W, Liu Y, Paus T, Horvath S, O'Connell JR, Guo X, Pausova Z, Assimes TL, Sotoodehnia N, Smith JA, Arnett DK, Deary IJ, Baccarelli AA, Bell JT, Whitsel E, Dehghan A, Levy D, Fornage M | 2017-12-07 | DNA methylation, Mendelian randomization, blood pressure, epigenome-wide association study, gene expression, sequence variation | American journal of human genetics |
Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand. | den Hollander W, Boer CG, Hart DJ, Yau MS, Ramos YFM, Metrustry S, Broer L, Deelen J, Cupples LA, Rivadeneira F, Kloppenburg M, Peters M, Spector TD, Hofman A, Slagboom PE, Nelissen RGHH, Uitterlinden AG, Felson DT, Valdes AM, Meulenbelt I, van Meurs JJB | 2017-12-01 | Matrix-Gla protein, functional study, genetics, genome-wide association study, hand osteoarthritis | Annals of the rheumatic diseases |
Maternal mortality: direct or indirect has become irrelevant. | van den Akker T, Nair M, Goedhart M, Schutte J, Schaap T, Knight M | 2017-12-01 | The Lancet. Global health | |
Thyroid Function Within the Normal Range, Subclinical Hypothyroidism, and the Risk of Atrial Fibrillation. | Baumgartner C, da Costa BR, Collet TH, Feller M, Floriani C, Bauer DC, Cappola AR, Heckbert SR, Ceresini G, Gussekloo J, den Elzen WPJ, Peeters RP, Luben R, Völzke H, Dörr M, Walsh JP, Bremner A, Iacoviello M, Macfarlane P, Heeringa J, Stott DJ, Westendorp RGJ, Khaw KT, Magnani JW, Aujesky D, Rodondi N | 2017-11-28 | atrial fibrillation, hypothyroidism, thyrotropin, thyroxine | Circulation |
Emergency obstetric care provision in Southern Ethiopia: a facility-based survey. | Windsma M, Vermeiden T, Braat F, Tsegaye AM, Gaym A, van den Akker T, Stekelenburg J | 2017-11-08 | emergency obstetric and neonatal care, health care facilities, manpower and services, maternal health services, maternal mortality, quality of Health care | BMJ open |
Homocysteine levels associate with subtle changes in leukocyte DNA methylation: an epigenome-wide analysis. | Mandaviya PR, Aïssi D, Dekkers KF, Joehanes R, Kasela S, Truong V, Stolk L, Heemst DV, Ikram MA, Lindemans J, Slagboom PE, Trégouët DA, Uitterlinden AG, Wei C, Wells P, Gagnon F, van Greevenbroek MM, Heijmans BT, Milani L, Morange PE, van Meurs JB, Heil SG | 2017-11-01 | 450 k array, DMP, DMR, DNA methylation, association, epigenome-wide analysis, homocysteine, meta-analysis | Epigenomics |
No Causal Association between 25-Hydroxyvitamin D and Features of Skin Aging: Evidence from a Bidirectional Mendelian Randomization Study. | Noordam R, Hamer MA, Pardo LM, van der Nat T, Kiefte-de Jong JC, Kayser M, Slagboom PE, Uitterlinden A, Zillikens MC, Beekman M, Nijsten T, van Heemst D, Gunn DA | 2017-11-01 | The Journal of investigative dermatology | |
The Cognitive decline in Older Patients with End stage renal disease (COPE) study – rationale and design. | Berkhout-Byrne N, Kallenberg MH, Gaasbeek A, Rabelink TJ, Hammer S, van Buchem MA, van Osch MJ, Kroft LJM, Boom H, Mooijaart SP, van Buren M | 2017-11-01 | Cognition, ESRD, dialysis, small vessel disease | Current medical research and opinion |
Optimising the ISAR-HP to screen efficiently for functional decline in older patients. | de Gelder J, Haenen E, Lucke JA, Klop HG, Blomaard LC, Smit RAJ, Mesri K, de Groot B, Fogteloo AJ, Anten S, Blauw GJ, Mooijaart SP | 2017-11-01 | The Netherlands journal of medicine | |
Thyroid status and mortality in nonagenarians from long-lived families and the general population. | van Vliet NA, van der Spoel E, Beekman M, Slagboom PE, Blauw GJ, Gussekloo J, Westendorp RGJ, van Heemst D | 2017-10-25 | familial, longevity, mortality, nonagenarians, thyroid | Aging |
Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. | Joshi PK, Pirastu N, Kentistou KA, Fischer K, Hofer E, Schraut KE, Clark DW, Nutile T, Barnes CLK, Timmers PRHJ, Shen X, Gandin I, McDaid AF, Hansen TF, Gordon SD, Giulianini F, Boutin TS, Abdellaoui A, Zhao W, Medina-Gomez C, Bartz TM, Trompet S, Lange LA, Raffield L, van der Spek A, Galesloot TE, Proitsi P, Yanek LR, Bielak LF, Payton A, Murgia F, Concas MP, Biino G, Tajuddin SM, Seppälä I, Amin N, Boerwinkle E, Børglum AD, Campbell A, Demerath EW, Demuth I, Faul JD, Ford I, Gialluisi A, Gögele M, Graff M, Hingorani A, Hottenga JJ, Hougaard DM, Hurme MA, Ikram MA, Jylhä M, Kuh D, Ligthart L, Lill CM, Lindenberger U, Lumley T, Mägi R, Marques-Vidal P, Medland SE, Milani L, Nagy R, Ollier WER, Peyser PA, Pramstaller PP, Ridker PM, Rivadeneira F, Ruggiero D, Saba Y, Schmidt R, Schmidt H, Slagboom PE, Smith BH, Smith JA, Sotoodehnia N, Steinhagen-Thiessen E, van Rooij FJA, Verbeek AL, Vermeulen SH, Vollenweider P, Wang Y, Werge T, Whitfield JB, Zonderman AB, Lehtimäki T, Evans MK, Pirastu M, Fuchsberger C, Bertram L, Pendleton N, Kardia SLR, Ciullo M, Becker DM, Wong A, Psaty BM, van Duijn CM, Wilson JG, Jukema JW, Kiemeney L, Uitterlinden AG, Franceschini N, North KE, Weir DR, Metspalu A, Boomsma DI, Hayward C, Chasman D, Martin NG, Sattar N, Campbell H, Esko T, Kutalik Z, Wilson JF | 2017-10-13 | Nature communications | |
Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism. | van Vliet NA, Noordam R, van Heemst D | 2017-10-05 | The New England journal of medicine | |
Lessons from Mendelian randomization studies on liver biomarkers: response to Abbasi. | Noordam R, Smit RAJ, Postmus I, Trompet S, van Heemst D | 2017-10-01 | International journal of epidemiology | |
Genetic variation in the obesity gene FTO is not associated with decreased fat oxidation: the NEO study. | Blauw LL, Noordam R, Trompet S, Berbée JFP, Rosendaal FR, van Heemst D, van Dijk KW, Mook-Kanamori DO, de Mutsert R, Rensen PCN | 2017-10-01 | International journal of obesity (2005) | |
Impact of age, sex and body mass index on cortisol secretion in 143 healthy adults. | Roelfsema F, van Heemst D, Iranmanesh A, Takahashi P, Yang R, Veldhuis JD | 2017-10-01 | approximate entropy, circadian rhythms, cortisol, deconvolution, human | Endocrine connections |
MRI Markers of Neurodegenerative and Neurovascular Changes in Relation to Postoperative Delirium and Postoperative Cognitive Decline. | Kant IMJ, de Bresser J, van Montfort SJT, Slooter AJC, Hendrikse J | 2017-10-01 | Postoperative delirium, magnetic resonance imaging, neurodegenerative brain changes, neurovascular brain changes, postoperative cognitive decline | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry |
Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health. | Plomp R, Ruhaak LR, Uh HW, Reiding KR, Selman M, Houwing-Duistermaat JJ, Slagboom PE, Beekman M, Wuhrer M | 2017-09-26 | Scientific reports | |
The most commonly used disease severity scores are inappropriate for risk stratification of older emergency department sepsis patients: an observational multi-centre study. | de Groot B, Stolwijk F, Warmerdam M, Lucke JA, Singh GK, Abbas M, Mooijaart SP, Ansems A, Esteve Cuevas L, Rijpsma D | 2017-09-11 | Disease severity scores, Emergency medical services, Infectious diseases, Mortality, Older patients, Risk stratification, Sepsis, qSOFA | Scandinavian journal of trauma, resuscitation and emergency medicine |
Classification of maternal deaths: where does the chain of events start? | van den Akker T, Bloemenkamp KWM, van Roosmalen J, Knight M | 2017-09-02 | Lancet (London, England) | |
Activation-Induced Autophagy Is Preserved in CD4+ T-Cells in Familial Longevity. | Raz Y, Guerrero-Ros I, Maier A, Slagboom PE, Atzmon G, Barzilai N, Macian F | 2017-09-01 | CD4+ T-cell, Centenarians, Immunosenescence, Macroautophagy, Proteostasis | The journals of gerontology. Series A, Biological sciences and medical sciences |
Historical demography and longevity genetics: Back to the future. | van den Berg N, Beekman M, Smith KR, Janssens A, Slagboom PE | 2017-09-01 | Demography, Genetics, Historical data, Inheritance, Longevity, Review | Ageing research reviews |
Small nucleoli are a cellular hallmark of longevity. | Tiku V, Jain C, Raz Y, Nakamura S, Heestand B, Liu W, Späth M, Suchiman HED, Müller RU, Slagboom PE, Partridge L, Antebi A | 2017-08-30 | Nature communications | |
Maternal and perinatal outcome after previous caesarean section in rural Rwanda. | Kalisa R, Rulisa S, van Roosmalen J, van den Akker T | 2017-08-25 | Elective repeat caesarean delivery, Maternal morbidity, Sub-Saharan Africa, Trial of labor, Vaginal birth after caesarean section | BMC pregnancy and childbirth |
Systemic Age-Associated DNA Hypermethylation of ELOVL2 Gene: In Vivo and In Vitro Evidences of a Cell Replication Process. | Bacalini MG, Deelen J, Pirazzini C, De Cecco M, Giuliani C, Lanzarini C, Ravaioli F, Marasco E, van Heemst D, Suchiman HED, Slieker R, Giampieri E, Recchioni R, Marcheselli F, Salvioli S, Vitale G, Olivieri F, Spijkerman AMW, Dollé MET, Sedivy JM, Castellani G, Franceschi C, Slagboom PE, Garagnani P | 2017-08-01 | Biomarker, Epigenetics, FHL2, Methylation | The journals of gerontology. Series A, Biological sciences and medical sciences |
High-Sensitivity Cardiac Troponin Concentration and Risk of First-Ever Cardiovascular Outcomes in 154,052 Participants. | Willeit P, Welsh P, Evans JDW, Tschiderer L, Boachie C, Jukema JW, Ford I, Trompet S, Stott DJ, Kearney PM, Mooijaart SP, Kiechl S, Di Angelantonio E, Sattar N | 2017-08-01 | biomarker, cardiovascular disease, coronary heart disease, primary prevention, stroke, systematic review | Journal of the American College of Cardiology |
Thyroid Function Tests in the Reference Range and Fracture: Individual Participant Analysis of Prospective Cohorts. | Aubert CE, Floriani C, Bauer DC, da Costa BR, Segna D, Blum MR, Collet TH, Fink HA, Cappola AR, Syrogiannouli L, Peeters RP, Åsvold BO, den Elzen WPJ, Luben RN, Bremner AP, Gogakos A, Eastell R, Kearney PM, Hoff M, Le Blanc E, Ceresini G, Rivadeneira F, Uitterlinden AG, Khaw KT, Langhammer A, Stott DJ, Westendorp RGJ, Ferrucci L, Williams GR, Gussekloo J, Walsh JP, Aujesky D, Rodondi N | 2017-08-01 | The Journal of clinical endocrinology and metabolism | |
Correction: The complex genetics of gait speed: genome-wide meta-analysis approach. | Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JD, Vered R, Deelen J, Arnold AM, Buchman AS, Tanaka T, Faul JD, Nethander M, Fornage M, Adams HH, Matteini AM, Callisaya ML, Smith AV, Yu L, De Jager PL, Evans DA, Gudnason V, Hofman A, Pattie A, Corley J, Launer LJ, Knopman DS, Parimi N, Turner ST, Bandinelli S, Beekman M, Gutman D, Sharvit L, Mooijaart SP, Liewald DC, Houwing-Duistermaat JJ, Ohlsson C, Moed M, Verlinden VJ, Mellström D, van der Geest JN, Karlsson M, Hernandez D, McWhirter R, Liu Y, Thomson R, Tranah GJ, Uitterlinden AG, Weir DR, Zhao W, Starr JM, Johnson AD, Ikram MA, Bennett DA, Cummings SR, Deary IJ, Harris TB, Kardia SLR, Mosley TH, Srikanth VK, Windham BG, Newman AB, Walston JD, Davies G, Evans DS, Slagboom EP, Ferrucci L, Kiel DP, Murabito JM, Atzmon G | 2017-07-01 | Aging | |
Regret about the decision to start dialysis: a cross-sectional Dutch national survey. | Berkhout-Byrne N, Gaasbeek A, Mallat MJK, Rabelink TJ, Mooijaart SP, Dekker FW, van Buren M | 2017-07-01 | The Netherlands journal of medicine | |
Secondary phenotype analysis in ascertained family designs: application to the Leiden longevity study. | Tissier R, Tsonaka R, Mooijaart SP, Slagboom E, Houwing-Duistermaat JJ | 2017-06-30 | ascertainment, family data, genetic association and heritability, mixed models, multivariate probit model | Statistics in medicine |
Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism. | Stott DJ, Rodondi N, Kearney PM, Ford I, Westendorp RGJ, Mooijaart SP, Sattar N, Aubert CE, Aujesky D, Bauer DC, Baumgartner C, Blum MR, Browne JP, Byrne S, Collet TH, Dekkers OM, den Elzen WPJ, Du Puy RS, Ellis G, Feller M, Floriani C, Hendry K, Hurley C, Jukema JW, Kean S, Kelly M, Krebs D, Langhorne P, McCarthy G, McCarthy V, McConnachie A, McDade M, Messow M, O'Flynn A, O'Riordan D, Poortvliet RKE, Quinn TJ, Russell A, Sinnott C, Smit JWA, Van Dorland HA, Walsh KA, Walsh EK, Watt T, Wilson R, Gussekloo J | 2017-06-29 | The New England journal of medicine | |
Validating the WHO maternal near miss tool: comparing high- and low-resource settings. | Witteveen T, Bezstarosti H, de Koning I, Nelissen E, Bloemenkamp KW, van Roosmalen J, van den Akker T | 2017-06-19 | Delivery, Maternal health, Maternal near miss, Maternal near miss-tool, Organ dysfunction, Resource setting comparison, Severe acute maternal morbidity, World health organization | BMC pregnancy and childbirth |
Incidence, management and outcome of women requiring massive transfusion after childbirth in the Netherlands: secondary analysis of a nationwide cohort study between 2004 and 2006. | Ramler PI, van den Akker T, Henriquez DDCA, Zwart JJ, van Roosmalen J | 2017-06-19 | Blood transfusion, Maternal morbidity, Maternal mortality, Obstetrics, Postpartum hemorrhage | BMC pregnancy and childbirth |
Thyroid Signaling, Insulin Resistance, and 2 Diabetes Mellitus: A Mendelian Randomization Study. | Bos MM, Smit RAJ, Trompet S, van Heemst D, Noordam R | 2017-06-01 | The Journal of clinical endocrinology and metabolism | |
Physicians’ Knowledge of and Attitudes Toward Use of Opioids in Long-Term Care Facilities. | Griffioen C, Willems EG, Kouwenhoven SM, Caljouw MAA, Achterberg WP | 2017-06-01 | barriers, long-term care facilities, opioids, pain | Pain practice : the official journal of World Institute of Pain |
Intellectual maturity and longevity: late-blooming composers and writers live longer than child prodigies. | Hafkamp MPJ, Slaets JPJ, van Bodegom D | 2017-05-30 | development, intellectual, life history theory, lifespan, longevity, maturity | Aging |
Cognitive Testing in People at Increased Risk of Dementia Using a Smartphone App: The iVitality Proof-of-Principle Study. | Jongstra S, Wijsman LW, Cachucho R, Hoevenaar-Blom MP, Mooijaart SP, Richard E | 2017-05-25 | cognition, neuropsychological tests, telemedicine | JMIR mHealth and uHealth |
Respectful maternity care in Ethiopian public health facilities. | Sheferaw ED, Bazant E, Gibson H, Fenta HB, Ayalew F, Belay TB, Worku MM, Kebebu AE, Woldie SA, Kim YM, van den Akker T, Stekelenburg J | 2017-05-16 | Birth companion, Birth positioning, Ethiopia, Health facility, Labor and delivery, Mistreatment of women, Respectful maternity care | Reproductive health |
A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. | Noordam R, Sitlani CM, Avery CL, Stewart JD, Gogarten SM, Wiggins KL, Trompet S, Warren HR, Sun F, Evans DS, Li X, Li J, Smith AV, Bis JC, Brody JA, Busch EL, Caulfield MJ, Chen YI, Cummings SR, Cupples LA, Duan Q, Franco OH, Méndez-Giráldez R, Harris TB, Heckbert SR, van Heemst D, Hofman A, Floyd JS, Kors JA, Launer LJ, Li Y, Li-Gao R, Lange LA, Lin HJ, de Mutsert R, Napier MD, Newton-Cheh C, Poulter N, Reiner AP, Rice KM, Roach J, Rodriguez CJ, Rosendaal FR, Sattar N, Sever P, Seyerle AA, Slagboom PE, Soliman EZ, Sotoodehnia N, Stott DJ, Stürmer T, Taylor KD, Thornton TA, Uitterlinden AG, Wilhelmsen KC, Wilson JG, Gudnason V, Jukema JW, Laurie CC, Liu Y, Mook-Kanamori DO, Munroe PB, Rotter JI, Vasan RS, Psaty BM, Stricker BH, Whitsel EA | 2017-05-01 | Genome-wide, QT interval electrocardiography, RR interval, drug-gene interaction, tri/tetracyclic antidepressants | Journal of medical genetics |
Temporal Relationship Between Cognitive and Physical Performance in Middle-Aged to Oldest Old People. | Stijntjes M, Aartsen MJ, Taekema DG, Gussekloo J, Huisman M, Meskers CGM, de Craen AJM, Maier AB | 2017-05-01 | Dynamic relationship, Executive function, Gait speed, Handgrip strength, Memory function | The journals of gerontology. Series A, Biological sciences and medical sciences |
Successful Geriatric Rehabilitation: Effects on Patients’ Outcome of a National Program to Improve Quality of Care, the SINGER Study. | Holstege MS, Caljouw MAA, Zekveld IG, van Balen R, de Groot AJ, van Haastregt JCM, Schols JMGA, Hertogh CMPM, Gussekloo J, Achterberg WP | 2017-05-01 | Geriatric rehabilitation, discharge destination, independence in ADL, length of stay, quality of care, successful rehabilitation | Journal of the American Medical Directors Association |
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. | Justice AE, Winkler TW, Feitosa MF, Graff M, Fisher VA, Young K, Barata L, Deng X, Czajkowski J, Hadley D, Ngwa JS, Ahluwalia TS, Chu AY, Heard-Costa NL, Lim E, Perez J, Eicher JD, Kutalik Z, Xue L, Mahajan A, Renström F, Wu J, Qi Q, Ahmad S, Alfred T, Amin N, Bielak LF, Bonnefond A, Bragg J, Cadby G, Chittani M, Coggeshall S, Corre T, Direk N, Eriksson J, Fischer K, Gorski M, Neergaard Harder M, Horikoshi M, Huang T, Huffman JE, Jackson AU, Justesen JM, Kanoni S, Kinnunen L, Kleber ME, Komulainen P, Kumari M, Lim U, Luan J, Lyytikäinen LP, Mangino M, Manichaikul A, Marten J, Middelberg RPS, Müller-Nurasyid M, Navarro P, Pérusse L, Pervjakova N, Sarti C, Smith AV, Smith JA, Stančáková A, Strawbridge RJ, Stringham HM, Sung YJ, Tanaka T, Teumer A, Trompet S, van der Laan SW, van der Most PJ, Van Vliet-Ostaptchouk JV, Vedantam SL, Verweij N, Vink JM, Vitart V, Wu Y, Yengo L, Zhang W, Hua Zhao J, Zimmermann ME, Zubair N, Abecasis GR, Adair LS, Afaq S, Afzal U, Bakker SJL, Bartz TM, Beilby J, Bergman RN, Bergmann S, Biffar R, Blangero J, Boerwinkle E, Bonnycastle LL, Bottinger E, Braga D, Buckley BM, Buyske S, Campbell H, Chambers JC, Collins FS, Curran JE, de Borst GJ, de Craen AJM, de Geus EJC, Dedoussis G, Delgado GE, den Ruijter HM, Eiriksdottir G, Eriksson AL, Esko T, Faul JD, Ford I, Forrester T, Gertow K, Gigante B, Glorioso N, Gong J, Grallert H, Grammer TB, Grarup N, Haitjema S, Hallmans G, Hamsten A, Hansen T, Harris TB, Hartman CA, Hassinen M, Hastie ND, Heath AC, Hernandez D, Hindorff L, Hocking LJ, Hollensted M, Holmen OL, Homuth G, Jan Hottenga J, Huang J, Hung J, Hutri-Kähönen N, Ingelsson E, James AL, Jansson JO, Jarvelin MR, Jhun MA, Jørgensen ME, Juonala M, Kähönen M, Karlsson M, Koistinen HA, Kolcic I, Kolovou G, Kooperberg C, Krämer BK, Kuusisto J, Kvaløy K, Lakka TA, Langenberg C, Launer LJ, Leander K, Lee NR, Lind L, Lindgren CM, Linneberg A, Lobbens S, Loh M, Lorentzon M, Luben R, Lubke G, Ludolph-Donislawski A, Lupoli S, Madden PAF, Männikkö R, Marques-Vidal P, Martin NG, McKenzie CA, McKnight B, Mellström D, Menni C, Montgomery GW, Musk AB, Narisu N, Nauck M, Nolte IM, Oldehinkel AJ, Olden M, Ong KK, Padmanabhan S, Peyser PA, Pisinger C, Porteous DJ, Raitakari OT, Rankinen T, Rao DC, Rasmussen-Torvik LJ, Rawal R, Rice T, Ridker PM, Rose LM, Bien SA, Rudan I, Sanna S, Sarzynski MA, Sattar N, Savonen K, Schlessinger D, Scholtens S, Schurmann C, Scott RA, Sennblad B, Siemelink MA, Silbernagel G, Slagboom PE, Snieder H, Staessen JA, Stott DJ, Swertz MA, Swift AJ, Taylor KD, Tayo BO, Thorand B, Thuillier D, Tuomilehto J, Uitterlinden AG, Vandenput L, Vohl MC, Völzke H, Vonk JM, Waeber G, Waldenberger M, Westendorp RGJ, Wild S, Willemsen G, Wolffenbuttel BHR, Wong A, Wright AF, Zhao W, Zillikens MC, Baldassarre D, Balkau B, Bandinelli S, Böger CA, Boomsma DI, Bouchard C, Bruinenberg M, Chasman DI, Chen YD, Chines PS, Cooper RS, Cucca F, Cusi D, Faire U, Ferrucci L, Franks PW, Froguel P, Gordon-Larsen P, Grabe HJ, Gudnason V, Haiman CA, Hayward C, Hveem K, Johnson AD, Wouter Jukema J, Kardia SLR, Kivimaki M, Kooner JS, Kuh D, Laakso M, Lehtimäki T, Marchand LL, März W, McCarthy MI, Metspalu A, Morris AP, Ohlsson C, Palmer LJ, Pasterkamp G, Pedersen O, Peters A, Peters U, Polasek O, Psaty BM, Qi L, Rauramaa R, Smith BH, Sørensen TIA, Strauch K, Tiemeier H, Tremoli E, van der Harst P, Vestergaard H, Vollenweider P, Wareham NJ, Weir DR, Whitfield JB, Wilson JF, Tyrrell J, Frayling TM, Barroso I, Boehnke M, Deloukas P, Fox CS, Hirschhorn JN, Hunter DJ, Spector TD, Strachan DP, van Duijn CM, Heid IM, Mohlke KL, Marchini J, Loos RJF, Kilpeläinen TO, Liu CT, Borecki IB, North KE, Cupples LA | 2017-04-26 | Nature communications | |
Variation in GP decisions on antihypertensive treatment in oldest-old and frail individuals across 29 countries. | Streit S, Verschoor M, Rodondi N, Bonfim D, Burman RA, Collins C, Biljana GK, Gintere S, Gómez Bravo R, Hoffmann K, Iftode C, Johansen KL, Kerse N, Koskela TH, Peštić SK, Kurpas D, Mallen CD, Maisoneuve H, Merlo C, Mueller Y, Muth C, Šter MP, Petrazzuoli F, Rosemann T, Sattler M, Švadlenková Z, Tatsioni A, Thulesius H, Tkachenko V, Torzsa P, Tsopra R, Canan T, Viegas RPA, Vinker S, de Waal MWM, Zeller A, Gussekloo J, Poortvliet RKE | 2017-04-20 | Clinical variation, Elderly, Frailty, General practitioners, Hypertension, Oldest-old | BMC geriatrics |
Vascular Cognitive Impairment in a Memory Clinic Population: Rationale and Design of the “Utrecht-Amsterdam Clinical Features and Prognosis in Vascular Cognitive Impairment” (TRACE-VCI) Study. | Boomsma JMF, Exalto LG, Barkhof F, van den Berg E, de Bresser J, Heinen R, Koek HL, Prins ND, Scheltens P, Weinstein HC, van der Flier WM, Biessels GJ | 2017-04-19 | dementia, memory clinic, prognosis, small vessel disease, vascular cognitive impairment, vascular disease | JMIR research protocols |
Short telomere length is associated with impaired cognitive performance in European ancestry cohorts. | Hägg S, Zhan Y, Karlsson R, Gerritsen L, Ploner A, van der Lee SJ, Broer L, Deelen J, Marioni RE, Wong A, Lundquist A, Zhu G, Hansell NK, Sillanpää E, Fedko IO, Amin NA, Beekman M, de Craen AJM, Degerman S, Harris SE, Kan KJ, Martin-Ruiz CM, Montgomery GW, Adolfsson AN, Reynolds CA, Samani NJ, Suchiman HED, Viljanen A, von Zglinicki T, Wright MJ, Hottenga JJ, Boomsma DI, Rantanen T, Kaprio JA, Nyholt DR, Martin NG, Nyberg L, Adolfsson R, Kuh D, Starr JM, Deary IJ, Slagboom PE, van Duijn CM, Codd V, Pedersen NL | 2017-04-18 | Translational psychiatry | |
Phenotypic screening of cannabinoid receptor 2 ligands shows different sensitivity to genotype. | Hillger JM, le Roy B, Wang Z, Mulder-Krieger T, Boomsma DI, Slagboom PE, Danen EHJ, IJzerman AP, Heitman LH | 2017-04-15 | 2-AG (PubMed CID: 5282280), AEA (PubMed CID: 5281969), AM251 (PubMed CID: 2125), AM630 (PubMed CID: 4302963), BAY59-3074 (PubMed CID: 10479060), CP55940 (PubMed CID: 10479060), Cannabinoid receptor 2, GW405833 (PubMed CID: 46916568), JWH133 (PubMed CID: 6918505), Label-free, Lymphoblastoid cell lines, Precision medicine, Single Nucleotide Polymorphism, WIN55212-2 (PubMed CID: 5311501) | Biochemical pharmacology |
Thyroid Status and Mortality Risk in Older Adults With Normal Thyrotropin: Sex Differences in the Milan Geriatrics 75+ Cohort Study. | Ogliari G, Smit RA, van der Spoel E, Mari D, Torresani E, Felicetta I, Lucchi TA, Rossi PD, van Heemst D, de Craen AJ, Westendorp RG | 2017-04-01 | Geriatric cohort, Longevity, Thyrotropin, Thyroxine | The journals of gerontology. Series A, Biological sciences and medical sciences |
Familial longevity is characterized by high circadian rhythmicity of serum cholesterol in healthy elderly individuals. | van den Berg R, Noordam R, Kooijman S, Jansen SWM, Akintola AA, Slagboom PE, Pijl H, Rensen PCN, Biermasz NR, van Heemst D | 2017-04-01 | aging, biological clock, cholesterol, circadian rhythm, longevity | Aging cell |
Validity of the three apathy items of the Geriatric Depression Scale (GDS-3A) in measuring apathy in older persons. | Bertens AS, Moonen JE, de Waal MW, Foster-Dingley JC, de Ruijter W, Gussekloo J, van der Mast RC, de Craen AJ | 2017-04-01 | Apathy Scale, Geriatric Depression Scale-3A (GDS-3A), apathy, older persons, validity | International journal of geriatric psychiatry |
A multi-component cognitive behavioural intervention for the treatment of fear of falling after hip fracture (FIT-HIP): protocol of a randomised controlled trial. | Scheffers-Barnhoorn MN, van Haastregt JC, Schols JM, Kempen GI, van Balen R, Visschedijk JH, van den Hout WB, Dumas EM, Achterberg WP, van Eijk M | 2017-03-20 | Cognitive behavioural therapy, Fear of falling, Geriatric rehabilitation, Hip fracture, Randomised controlled trial | BMC geriatrics |
Effect of intranasally administered insulin on cerebral blood flow and perfusion; a randomized experiment in young and older adults. | Akintola AA, van Opstal AM, Westendorp RG, Postmus I, van der Grond J, van Heemst D | 2017-03-14 | aging, cerebral blood flow, continuous arterial spin labelling (CASL), intranasal insulin, magnetic resonance imaging (MRI), phase contrast MR angiography | Aging |
Prolonged high-fat diet induces gradual and fat depot-specific DNA methylation changes in adult mice. | Zwamborn RA, Slieker RC, Mulder PC, Zoetemelk I, Verschuren L, Suchiman HE, Toet KH, Droog S, Slagboom PE, Kooistra T, Kleemann R, Heijmans BT | 2017-03-03 | Scientific reports | |
Measurement properties of the EQ-5D across four major geriatric conditions: Findings from TOPICS-MDS. | Lutomski JE, Krabbe PF, Bleijenberg N, Blom J, Kempen GI, MacNeil-Vroomen J, Muntinga ME, Steyerburg E, Olde-Rikkert MG, Melis RJ | 2017-03-03 | Dizziness, EQ-5D, Hearing loss, Joint diseases, Quality of life, Urinary incontinence | Health and quality of life outcomes |
Care-Related Quality of Life of Informal Caregivers After Geriatric Rehabilitation. | van Dam PH, Achterberg WP, Caljouw MA | 2017-03-01 | Care-related quality of life, CarerQoL, geriatric rehabilitation, informal care, skilled nursing facility | Journal of the American Medical Directors Association |
Study protocol; Thyroid hormone Replacement for Untreated older adults with Subclinical hypothyroidism – a randomised placebo controlled Trial (TRUST). | Stott DJ, Gussekloo J, Kearney PM, Rodondi N, Westendorp RG, Mooijaart S, Kean S, Quinn TJ, Sattar N, Hendry K, Du Puy R, Den Elzen WP, Poortvliet RK, Smit JW, Jukema JW, Dekkers OM, Blum M, Collet TH, McCarthy V, Hurley C, Byrne S, Browne J, Watt T, Bauer D, Ford I | 2017-02-03 | Elderly, Levothyroxine, Quality of life, Randomised controlled trial, Subclinical hypothyroidism, Thyroid disease | BMC endocrine disorders |
Human Plasma N-glycosylation as Analyzed by Matrix-Assisted Laser Desorption/Ionization-Fourier Transform Ion Cyclotron Resonance-MS Associates with Markers of Inflammation and Metabolic Health. | Reiding KR, Ruhaak LR, Uh HW, El Bouhaddani S, van den Akker EB, Plomp R, McDonnell LA, Houwing-Duistermaat JJ, Slagboom PE, Beekman M, Wuhrer M | 2017-02-01 | Molecular & cellular proteomics : MCP | |
A framework for the detection of de novo mutations in family-based sequencing data. | Francioli LC, Cretu-Stancu M, Garimella KV, Fromer M, Kloosterman WP, Samocha KE, Neale BM, Daly MJ, Banks E, DePristo MA, de Bakker PI | 2017-02-01 | European journal of human genetics : EJHG | |
Complement receptor 1 gene polymorphisms are associated with cardiovascular risk. | de Vries MA, Trompet S, Mooijaart SP, Smit RA, Böhringer S, Castro Cabezas M, Jukema JW | 2017-02-01 | Apolipoprotein B, Atherosclerosis, C-reactive protein, Inflammation, Myocardial infarction | Atherosclerosis |
Predicting Risk of Cognitive Decline in Very Old Adults Using Three Models: The Framingham Stroke Risk Profile; the Cardiovascular Risk Factors, Aging, and Dementia Model; and Oxi-Inflammatory Biomarkers. | Harrison SL, de Craen AJ, Kerse N, Teh R, Granic A, Davies K, Wesnes KA, den Elzen WP, Gussekloo J, Kirkwood TB, Robinson L, Jagger C, Siervo M, Stephan BC | 2017-02-01 | biomarkers, cardiovascular risk, cognitive decline, cognitive function, dementia | Journal of the American Geriatrics Society |
The complex genetics of gait speed: genome-wide meta-analysis approach. | Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JD, Vered R, Deelen J, Arnold AM, Buchman AS, Tanaka T, Faul JD, Nethander M, Fornage M, Adams HH, Matteini AM, Callisaya ML, Smith AV, Yu L, De Jager PL, Evans DA, Gudnason V, Hofman A, Pattie A, Corley J, Launer LJ, Knopman DS, Parimi N, Turner ST, Bandinelli S, Beekman M, Gutman D, Sharvit L, Mooijaart SP, Liewald DC, Houwing-Duistermaat JJ, Ohlsson C, Moed M, Verlinden VJ, Mellström D, van der Geest JN, Karlsson M, Hernandez D, McWhirter R, Liu Y, Thomson R, Tranah GJ, Uitterlinden AG, Weir DR, Zhao W, Starr JM, Johnson AD, Ikram MA, Bennett DA, Cummings SR, Deary IJ, Harris TB, Kardia SL, Mosley TH, Srikanth VK, Windham BG, Newman AB, Walston JD, Davies G, Evans DS, Slagboom EP, Ferrucci L, Kiel DP, Murabito JM, Atzmon G | 2017-01-10 | GWAS, aging, gait speed, meta-analysis | Aging |
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity. | Wahl S, Drong A, Lehne B, Loh M, Scott WR, Kunze S, Tsai PC, Ried JS, Zhang W, Yang Y, Tan S, Fiorito G, Franke L, Guarrera S, Kasela S, Kriebel J, Richmond RC, Adamo M, Afzal U, Ala-Korpela M, Albetti B, Ammerpohl O, Apperley JF, Beekman M, Bertazzi PA, Black SL, Blancher C, Bonder MJ, Brosch M, Carstensen-Kirberg M, de Craen AJ, de Lusignan S, Dehghan A, Elkalaawy M, Fischer K, Franco OH, Gaunt TR, Hampe J, Hashemi M, Isaacs A, Jenkinson A, Jha S, Kato N, Krogh V, Laffan M, Meisinger C, Meitinger T, Mok ZY, Motta V, Ng HK, Nikolakopoulou Z, Nteliopoulos G, Panico S, Pervjakova N, Prokisch H, Rathmann W, Roden M, Rota F, Rozario MA, Sandling JK, Schafmayer C, Schramm K, Siebert R, Slagboom PE, Soininen P, Stolk L, Strauch K, Tai ES, Tarantini L, Thorand B, Tigchelaar EF, Tumino R, Uitterlinden AG, van Duijn C, van Meurs JB, Vineis P, Wickremasinghe AR, Wijmenga C, Yang TP, Yuan W, Zhernakova A, Batterham RL, Smith GD, Deloukas P, Heijmans BT, Herder C, Hofman A, Lindgren CM, Milani L, van der Harst P, Peters A, Illig T, Relton CL, Waldenberger M, Järvelin MR, Bollati V, Soong R, Spector TD, Scott J, McCarthy MI, Elliott P, Bell JT, Matullo G, Gieger C, Kooner JS, Grallert H, Chambers JC | 2017-01-05 | Nature | |
Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. | van Rooij FJA, Qayyum R, Smith AV, Zhou Y, Trompet S, Tanaka T, Keller MF, Chang LC, Schmidt H, Yang ML, Chen MH, Hayes J, Johnson AD, Yanek LR, Mueller C, Lange L, Floyd JS, Ghanbari M, Zonderman AB, Jukema JW, Hofman A, van Duijn CM, Desch KC, Saba Y, Ozel AB, Snively BM, Wu JY, Schmidt R, Fornage M, Klein RJ, Fox CS, Matsuda K, Kamatani N, Wild PS, Stott DJ, Ford I, Slagboom PE, Yang J, Chu AY, Lambert AJ, Uitterlinden AG, Franco OH, Hofer E, Ginsburg D, Hu B, Keating B, Schick UM, Brody JA, Li JZ, Chen Z, Zeller T, Guralnik JM, Chasman DI, Peters LL, Kubo M, Becker DM, Li J, Eiriksdottir G, Rotter JI, Levy D, Grossmann V, Patel KV, Chen CH, Ridker PM, Tang H, Launer LJ, Rice KM, Li-Gao R, Ferrucci L, Evans MK, Choudhuri A, Trompouki E, Abraham BJ, Yang S, Takahashi A, Kamatani Y, Kooperberg C, Harris TB, Jee SH, Coresh J, Tsai FJ, Longo DL, Chen YT, Felix JF, Yang Q, Psaty BM, Boerwinkle E, Becker LC, Mook-Kanamori DO, Wilson JG, Gudnason V, O'Donnell CJ, Dehghan A, Cupples LA, Nalls MA, Morris AP, Okada Y, Reiner AP, Zon LI, Ganesh SK | 2017-01-05 | American journal of human genetics | |
Assessment of health status by molecular measures in adults ranging from middle-aged to old: Ready for clinical use? | Waaijer ME, Westendorp RG, Goldeck D, Gunn DA, Pawelec G, Stijntjes M, Slagboom PE, Maier AB | 2017-01-01 | Aging, CD57, Functional capacity, Immunosenescence, Senescence, p16INK4a | Experimental gerontology |
Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study. | de Vries PS, Sabater-Lleal M, Chasman DI, Trompet S, Ahluwalia TS, Teumer A, Kleber ME, Chen MH, Wang JJ, Attia JR, Marioni RE, Steri M, Weng LC, Pool R, Grossmann V, Brody JA, Venturini C, Tanaka T, Rose LM, Oldmeadow C, Mazur J, Basu S, Frånberg M, Yang Q, Ligthart S, Hottenga JJ, Rumley A, Mulas A, de Craen AJ, Grotevendt A, Taylor KD, Delgado GE, Kifley A, Lopez LM, Berentzen TL, Mangino M, Bandinelli S, Morrison AC, Hamsten A, Tofler G, de Maat MP, Draisma HH, Lowe GD, Zoledziewska M, Sattar N, Lackner KJ, Völker U, McKnight B, Huang J, Holliday EG, McEvoy MA, Starr JM, Hysi PG, Hernandez DG, Guan W, Rivadeneira F, McArdle WL, Slagboom PE, Zeller T, Psaty BM, Uitterlinden AG, de Geus EJ, Stott DJ, Binder H, Hofman A, Franco OH, Rotter JI, Ferrucci L, Spector TD, Deary IJ, März W, Greinacher A, Wild PS, Cucca F, Boomsma DI, Watkins H, Tang W, Ridker PM, Jukema JW, Scott RJ, Mitchell P, Hansen T, O'Donnell CJ, Smith NL, Strachan DP, Dehghan A | 2017-01-01 | PloS one | |
Identification of context-dependent expression quantitative trait loci in whole blood. | Zhernakova DV, Deelen P, Vermaat M, van Iterson M, van Galen M, Arindrarto W, van 't Hof P, Mei H, van Dijk F, Westra HJ, Bonder MJ, van Rooij J, Verkerk M, Jhamai PM, Moed M, Kielbasa SM, Bot J, Nooren I, Pool R, van Dongen J, Hottenga JJ, Stehouwer CD, van der Kallen CJ, Schalkwijk CG, Zhernakova A, Li Y, Tigchelaar EF, de Klein N, Beekman M, Deelen J, van Heemst D, van den Berg LH, Hofman A, Uitterlinden AG, van Greevenbroek MM, Veldink JH, Boomsma DI, van Duijn CM, Wijmenga C, Slagboom PE, Swertz MA, Isaacs A, van Meurs JB, Jansen R, Heijmans BT, 't Hoen PA, Franke L | 2017-01-01 | Nature genetics | |
Disease variants alter transcription factor levels and methylation of their binding sites. | Bonder MJ, Luijk R, Zhernakova DV, Moed M, Deelen P, Vermaat M, van Iterson M, van Dijk F, van Galen M, Bot J, Slieker RC, Jhamai PM, Verbiest M, Suchiman HE, Verkerk M, van der Breggen R, van Rooij J, Lakenberg N, Arindrarto W, Kielbasa SM, Jonkers I, van 't Hof P, Nooren I, Beekman M, Deelen J, van Heemst D, Zhernakova A, Tigchelaar EF, Swertz MA, Hofman A, Uitterlinden AG, Pool R, van Dongen J, Hottenga JJ, Stehouwer CD, van der Kallen CJ, Schalkwijk CG, van den Berg LH, van Zwet EW, Mei H, Li Y, Lemire M, Hudson TJ, Slagboom PE, Wijmenga C, Veldink JH, van Greevenbroek MM, van Duijn CM, Boomsma DI, Isaacs A, Jansen R, van Meurs JB, 't Hoen P |