Below a list of publications is given related to LEGend.
| Title | Authors | Date | Keywords | Issue name |
|---|---|---|---|---|
| Predicting the risks and recognizing the signs: a two-year prospective population-based study on pregnant women with uterine rupture in The Netherlands. | Overtoom EM, Huynh TN, Rosman AN, Zwart JJ, Schaap TP, Vogelvang TE, van den Akker T, Bloemenkamp KWM | 2024-12-01 | CTG tracings, Uterine rupture, adverse outcome, maternal morbidity, perinatal morbidity | The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians |
| Health workers’ perspectives on the quality of maternal and newborn health care around the time of childbirth: Results of the Improving MAternal Newborn carE in the EURO Region (IMAgiNE EURO) project in 12 countries of the World Health Organization European Region. | Valente EP, Mariani I, Bomben A, Morano S, Gemperle M, Otelea MR, Miani C, Elden H, Sarantaki A, Costa R, Baranowska B, König-Bachmann M, Kongslien S, Drandić D, Rozée V, Nespoli A, Abderhalden-Zellweger A, Nanu I, Batram-Zantvoort S, Linden K, Metallinou D, Dias H, Tataj-Puzyna U, D'Costa E, Nedberg IH, Kurbanović M, de La Rochebrochard E, Fumagalli S, Grylka-Baeschlin S, Handra CM, Zaigham M, Orovou E, Barata C, Szlendak B, Zenzmaier C, Vik ES, Liepinaitienė A, Drglin Z, Arendt M, Sacks E, Lazzerini M | 2024-09-06 | Journal of global health | |
| Validity and reliability of the Pain Assessment in Impaired Cognition 15 (PAIC15) observation scale in persons with aphasia. | de Vries NJ, Smaling HJA, van der Steen JT, Achterberg WP | 2024-09-05 | Aphasia, Pain observation instrument, Pain scales, Self-report pain | BMC neurology |
| Late reproduction is associated with extended female survival but not with familial longevity. | de Kat AC, Roelofs F, Slagboom PE, Broekmans FJM, Beekman M, Berg NVD | 2024-09-01 | Ageing, Fertility, Longevity | Reproductive biomedicine online |
| The contribution of suicide to maternal mortality: A nationwide population-based cohort study. | Lommerse KM, Mérelle S, Rietveld AL, Berkelmans G, van den Akker T | 2024-09-01 | maternal mortality, pregnancy‐related mortality, suicide, underreporting | BJOG : an international journal of obstetrics and gynaecology |
| Prophylactic Radiologic Interventions for Postpartum Hemorrhage Control in Women With Placenta Accreta Spectrum Disorder: A Systematic Review and Meta-analysis. | Bonsen LR, Sleijpen K, Hendriks J, Urlings TAJ, Dekkers OM, le Cessie S, van de Velde M, Gurung P, van den Akker T, van der Bom JG, Henriquez DDCA | 2024-09-01 | Obstetrics and gynecology | |
| Influence of arterial transit time delays on the differentiation between tumor progression and pseudoprogression in glioblastoma by arterial spin labeling magnetic resonance imaging. | van Dorth D, Jiang FY, Schmitz-Abecassis B, Croese RJI, Taphoorn MJB, Smits M, Koekkoek JAF, Dirven L, de Bresser J, van Osch MJP | 2024-09-01 | arterial spin labeling, arterial transit time, glioblastoma, perfusion MRI, pseudoprogression, tumor progression | NMR in biomedicine |
| Prevalence and 3-month follow-up of cerebrovascular MRI markers in hospitalized COVID-19 patients: the CORONIS study. | van Lith TJ, Sluis WM, Wijers NT, Meijer FJA, Ulzen KK, de Bresser J, Dankbaar JW, de Mast Q, Klok FA, Cannegieter SC, Wermer MJH, Huisman MV, Tuladhar AM, van der Worp HB, de Leeuw FE | 2024-09-01 | Brain ischemia, COVID-19, Cerebrovascular disorders, MRI, SARS-CoV-2, WMH | Neuroradiology |
| Genome-Wide Interaction Analyses of Serum Calcium on Ventricular Repolarization Time in 125 393 Participants. | Young WJ, van der Most PJ, Bartz TM, Bos MM, Biino G, Duong T, Foco L, Lominchar JT, Müller-Nurasyid M, Nardone GG, Pecori A, Ramirez J, Repetto L, Schramm K, Shen X, van Duijvenboden S, van Heemst D, Weiss S, Yao J, Benjamins JW, Alonso A, Spedicati B, Biggs ML, Brody JA, Dörr M, Fuchsberger C, Gögele M, Guo X, Ikram MA, Jukema JW, Kääb S, Kanters JK, Lin HJ, Linneberg A, Nauck M, Nolte IM, Pianigiani G, Santin A, Soliman EZ, Tesolin P, Vaccargiu S, Waldenberger M, van der Harst P, Verweij N, Arking DE, Concas MP, De Grandi A, Girotto G, Grarup N, Kavousi M, Mook-Kanamori DO, Navarro P, Orini M, Padmanabhan S, Pattaro C, Peters A, Pirastu M, Pramstaller PP, Heckbert SR, Sinner M, Snieder H, Völker U, Wilson JF, Gauderman WJ, Lambiase PD, Sotoodehnia N, Tinker A, Warren HR, Noordam R, Munroe PB | 2024-08-29 | ECG intervals, calcium, gene‐lifestyle interaction, genome‐wide association study, ventricular repolarization | Journal of the American Heart Association |
| Temporalities of oxytocin for labour augmentation: a mixed-methods study of time factors shaping labour practices in a busy maternity unit in Tanzania. | Kujabi ML, Maembe L, Nkungu D, Maaløe N, D'mello BS, van Roosmalen J, van den Akker T, Konradsen F, Hussein K, Pallangyo E, Skovdal M, Sørensen JB | 2024-08-29 | Augmentation, Guidelines, Intrapartum, Low-resource, Oxytocin, PartoMa, Partograph, Prolonged labour, Time-pressure, Urbanisation | BMC pregnancy and childbirth |
| NMR metabolomics-guided DNA methylation mortality predictors. | Bizzarri D, Reinders MJT, Kuiper L, Beekman M, Deelen J, van Meurs JBJ, van Dongen J, Pool R, Boomsma DI, Ghanbari M, Franke L, Slagboom PE, van den Akker EB | 2024-08-17 | Ageing biomarkers, DNA methylation predictors, Epidemiology, Epigenetic clock, Metabolic risk score, NMR metabolomics | EBioMedicine |
| Secondary integrated analysis of multi-tissue transcriptomic responses to a combined lifestyle intervention in older adults from the GOTO nonrandomized trial | Bogaards FA, Gehrmann T, Beekman M, Lakenberg N, Suchiman HED, de Groot CPGM, Reinders MJT, Slagboom PE | 2024-08-15 | Nature Communications | |
| DOSAGE study: protocol for a phase III non-inferiority randomised trial investigating dose-reduced chemotherapy for advanced colorectal cancer in older patients. | Baltussen JC, van den Bos F, Slingerland M, Binda TRR, Liefers GJ, van den Hout WB, Fiocco M, Verschoor AJ, Cloos-van Balen M, Holterhues C, Houtsma D, Jochems A, Spierings LEAMM, van Bodegom-Vos L, Mooijaart SP, Gelderblom H, Speetjens FM, de Glas NA, Portielje JEA | 2024-08-13 | CHEMOTHERAPY, GERIATRIC MEDICINE, Gastrointestinal tumours, ONCOLOGY, Quality of Life, Randomized Controlled Trial | BMJ open |
| Post-COVID-19 recovery and geriatric rehabilitation care: a European inter-country comparative study. | van Tol LS, Lin T, Caljouw MAA, Cesari M, Dockery F, Everink IHJ, Francis BN, Gordon AL, Grund S, Matchekhina L, Bazan LMP, Topinková E, Vassallo MA, Achterberg WP, Haaksma ML | 2024-08-13 | COVID-19, Europe, Geriatric rehabilitation, Recovery | European geriatric medicine |
| Allocation and value of curative oncological treatment in frail and fit older patients with esophageal cancer: An observational cohort study. | van der Poort EKJ, van Holstein Y, Slingerland M, Trompet S, van den Bos F, Portielje JEA, Steyerberg EW, van den Akker-van Marle ME, Bos WJW, Mooijaart SP, van den Hout WB | 2024-08-12 | Esophageal cancer, Frailty, Hospital costs, Patient-relevant outcomes, Value-based health care | Journal of geriatric oncology |
| White matter hyperintensity shape is related to long-term progression of cerebrovascular disease in community-dwelling older adults. | Kuhn-Keller JA, Sigurdsson S, Launer LJ, van Buchem MA, van Osch MJ, Gudnason V, de Bresser J | 2024-08-07 | Cerebral small vessel disease, cerebrovascular disease, magnetic resonance imaging, vascular cognitive impairment, white matter hyperintensities | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism |
| The association of inflammatory markers with frailty and in-hospital mortality in older COVID-19 patients. | Tran Van Hoi E, Appelman B, Mooijaart S, Dalm VASH, Polinder Bos HA, van Heemst D, van Raaij BFM, Noordam R, Kuranova A, Hoogerwerf JJ, Peeters G, Smorenberg A | 2024-08-06 | Ageing, COVID-19, Frailty, Immunosenescence, Inflammation | Experimental gerontology |
| Older adults exercising ON TIME: protocol for a randomized controlled cross-over study to assess the effect of physical activity timing on insomnia severity. | Albalak G, Noordam R, van der Elst M, Kervezee L, Exadaktylos V, van Bodegom D, van Heemst D | 2024-08-05 | Biological clock, Crossover randomized controlled trial, Exercise, Physical activity, Sleep, Timing, Zeitgeber | Trials |
| Phenotype prediction using biologically interpretable neural networks on multi-cohort multi-omics data. | van Hilten A, van Rooij J, Ikram MA, Niessen WJ, van Meurs JBJ, Roshchupkin GV | 2024-08-02 | NPJ systems biology and applications | |
| Physical activity and fiber intake beneficial for muscle mass and strength preservation during aging: A comprehensive cross-sectional study in the UK biobank cohort. | Morwani-Mangnani J, Rodriguez-Girondo M, Singh-Povel C, Verlaan S, Beekman M, Slagboom PE | 2024-08-01 | Biology of aging, Healthy aging, Lifestyle, Muscle health, Nutrition, UK biobank, fiber intake | Experimental gerontology |
| Inconsistent definitions of prolonged labor in international literature: a scoping review. | Bakker W, Sandberg EM, Keetels S, Schoones JW, Kujabi ML, Maaløe N, Maswime S, van den Akker T | 2024-08-01 | active support of labor, definition, labor dystocia, labor management, labor progress, partograph, prolonged first stage of labor, prolonged second stage of labor | AJOG global reports |
| The Impact of Delirium on Recovery in Geriatric Rehabilitation after Acute Infection. | Minnema J, Polinder-Bos HA, Cesari M, Dockery F, Everink IHJ, Francis BN, Gordon AL, Grund S, Perez Bazan LM, Eruslanova K, Topinková E, Vassallo MA, Faes MC, van Tol LS, Caljouw MAA, Achterberg WP, Haaksma ML | 2024-08-01 | ADL, COVID-19, Delirium, Geriatric rehabilitation, Older adults, QoL, Recovery | Journal of the American Medical Directors Association |
| Service provision for Frailty in European Emergency Departments (FEED): a survey of operational characteristics. | Fehlmann CA, Mc Loughlin K, Cosgriff EJ, Ferrick JF, van Oppen JD | 2024-07-29 | Delirium, Emergency care, Frailty, Health services | Scandinavian journal of trauma, resuscitation and emergency medicine |
| Person-centred decisions in emergency care for older people living with frailty: principles and practice. | van Oppen JD, Coats T, Conroy S, Hayden S, Heeren P, Hullick C, Liu S, Lucke J, Lukin B, McNamara R, Melady D, Mooijaart SP, Rosen T, Banerjee J | 2024-07-26 | emergency departments, ethics, frailty, geriatrics | Emergency medicine journal : EMJ |
| Effect of COVID-19 lockdown on maternity care and maternal outcome in the Netherlands: a national quasi-experimental study. | Gravesteijn BY, Boderie NW, van den Akker T, Bertens LCM, Bloemenkamp K, Burgos Ochoa L, de Jonge A, Kazemier BM, Klein PPF, Kwint-Reijnders I, Labrecque JA, Mol BW, Obermann-Borst SA, Peters L, Ravelli ACJ, Rosman A, Been JV, de Groot CJ | 2024-07-20 | COVID-19, Homebirth, Maternal health, Natural experiment, SARS-CoV−2 | Public health |
| Association between bilirubin and biomarkers of metabolic health and oxidative stress in the MARK-AGE cohort. | Schoissengeier V, Maqboul L, Weber D, Grune T, Bürkle A, Moreno-Villaneuva M, Franceschi C, Capri M, Bernhard J, Toussaint O, Debacq-Chainiaux F, Weinberger B, Gonos ES, Sikora E, Dollé M, Jansen E, Slagboom PE, Hervonnen A, Hurme M, Breusing N, Frank J, Bulmer AC, Wagner KH | 2024-07-19 | human metabolism, pathology, public health | iScience |
| Time to redefine prolonged third stage of labor? A systematic review and meta-analysis of the length of the third stage of labor and adverse maternal outcome after vaginal birth. | de Vries PLM, Veenstra E, Baud D, Legardeur H, Kallianidis AF, van den Akker T | 2024-07-19 | adverse maternal outcome, manual removal of the placenta, postpartum hemorrhage, third stage of labor, timing | American journal of obstetrics and gynecology |
| A Large-Scale Genome-Wide Study of Gene-Sleep Duration Interactions for Blood Pressure in 811,405 Individuals from Diverse Populations. | Wang H, Nagarajan P, Winkler T, Bentley A, Miller C, Kraja A, Schwander K, Lee S, Wang W, Brown M, Morrison J, Giri A, O'Connell J, Bartz T, de Las Fuentes L, Gudmundsdottir V, Guo X, Harris S, Huang Z, Kals M, Kho M, Lefevre C, Luan J, Lyytikäinen LP, Mangino M, Milaneschi Y, Palmer N, Rao V, Rauramaa R, Shen B, Stadler S, Sun Q, Tang J, Thériault S, van der Graaf A, van der Most P, Wang Y, Weiss S, Westerman K, Yang Q, Yasuharu T, Zhao W, Zhu W, Altschul D, Ansari MAY, Anugu P, Argoty-Pantoja A, Arzt M, Aschard H, Attia J, Bazzano L, Breyer M, Brody J, Cade B, Chen HH, Chen YI, Chen Z, de Vries P, Dimitrov L, Do A, Du J, Dupont C, Edwards T, Evans M, Faquih T, Felix S, Fisher-Hoch S, Floyd J, Graff M, Charles Gu C, Gu D, Hairston K, Hanley A, Heid I, Heikkinen S, Highland H, Hood M, Kähönen M, Karvonen-Gutierrez C, Kawaguchi T, Kazuya S, Tanika K, Komulainen P, Levy D, Lin H, Liu P, Marques-Vidal P, McCormick J, Mei H, Meigs J, Menni C, Nam K, Nolte I, Pacheco N, Petty L, Polikowsky H, Province M, Psaty B, Raffield L, Raitakari O, Rich S, Riha R, Risch L, Risch M, Ruiz-Narvaez E, Scott R, Sitlani C, Smith J, Sofer T, Teder-Laving M, Völker U, Vollenweider P, Wang G, van Dijk KW, Wilson O, Xia R, Yao J, Young K, Zhang R, Zhu X, Below J, Böger C, Conen D, Cox S, Dörr M, Feitosa M, Fox E, Franceschini N, Gharib S, Gudnason V, Harlow S, He J, Holliday E, Kutalik Z, Lakka T, Lawlor D, Lee S, Lehtimäki T, Li C, Liu CT, Mägi R, Matsuda F, Morrison A, Penninx BWJH, Peyser P, Rotter J, Snieder H, Spector T, Wagenknecht L, Wareham N, Zonderman A, North K, Fornage M, Hung A, Manning A, Gauderman W, Chen H, Munroe P, Rao D, van Heemst D, Redline S, Noordam R | 2024-07-17 | Research square | |
| Mind-body practices for people living with dementia and their family carers: a systematic review. | van der Ploeg ES, Bitane RM, Schoones JW, Achterberg WP, Smaling HJA | 2024-07-16 | dementia, dyads, family carers, mind-body practices, systematic review | Journal of complementary & integrative medicine |
| The performance of metabolomics-based prediction scores for mortality in older patients with solid tumors. | van Holstein Y, Mooijaart SP, van Oevelen M, van Deudekom FJ, Vojinovic D, Bizzarri D, van den Akker EB, Noordam R, Deelen J, van Heemst D, de Glas NA, Holterhues C, Labots G, van den Bos F, Beekman M, Slagboom PE, van Munster BC, Portielje JEA, Trompet S | 2024-07-04 | Biomarkers, Geriatric assessment, Geriatric oncology, Metabolomics, Mortality | GeroScience |
| Temporal dynamics of depressive symptoms and cognitive decline in the oldest old: dynamic time warp analysis of the Leiden 85-plus study. | van der Slot AJC, Bertens AS, Trompet S, Mooijaart SP, Gussekloo J, van den Bos F, Giltay EJ | 2024-07-02 | cognitive impairment, depression, network analysis, older people, oldest old, time series | Age and ageing |
| Effects of the discontinuation of antihypertensive treatment on neuropsychiatric symptoms and quality of life in nursing home residents with dementia (DANTON): a multicentre, open-label, blinded-outcome, randomised controlled trial. | Bogaerts JMK, Gussekloo J, de Jong-Schmit BEM, Le Cessie S, Mooijaart SP, van der Mast RC, Achterberg WP, Poortvliet RKE | 2024-07-02 | antihypertensive treatment, dementia, deprescribing, hypertension, older people, randomised controlled trial | Age and ageing |
| Tolerability and effectiveness of palbociclib in older women with metastatic breast cancer. | Baltussen JC, Mooijaart SP, Vulink AJE, Houtsma D, Van der Deure WM, Westerman EM, Oosterkamp HM, Spierings LEAMM, van den Bos F, de Glas NA, Portielje JEA | 2024-07-01 | Metastatic breast cancer, Older patients, Palbociclib, Real-world data, Tolerability, Toxicity | Breast cancer research and treatment |
| Professional identity formation of medical students in relation to the care of older persons: a review of the literature. | Moll-Jongerius A, Langeveld K, Tong W, Masud T, Kramer AWM, Achterberg WP | 2024-07-01 | Professional identity formation, geriatrics, medical students, older persons, undergraduate medical education | Gerontology & geriatrics education |
| SMIM1 absence is associated with reduced energy expenditure and excess weight. | Stefanucci L, Moslemi C, Tomé AR, Virtue S, Bidault G, Gleadall NS, Watson LPE, Kwa JE, Burden F, Farrow S, Chen J, Võsa U, Burling K, Walker L, Ord J, Barker P, Warner J, Frary A, Renhstrom K, Ashford SE, Piper J, Biggs G, Erber WN, Hoffman GJ, Schoenmakers N, Erikstrup C, Rieneck K, Dziegiel MH, Ullum H, Azzu V, Vacca M, Aparicio HJ, Hui Q, Cho K, Sun YV, Wilson PW, Bayraktar OA, Vidal-Puig A, Ostrowski SR, Astle WJ, Olsson ML, Storry JR, Pedersen OB, Ouwehand WH, Chatterjee K, Vuckovic D, Frontini M | 2024-06-17 | BMI, SMIM1, Translation to patients, Vel, blood groups, dyslipidemia, metabolism, obesity, population genetics, weight | Med (New York, N.Y.) |
| Prevalence and burden of pain across the entire spectrum of Huntington’s disease. | Sprenger GP, van Zwet EW, Bakels HS, Achterberg WP, Roos RA, de Bot ST | 2024-06-17 | MOVEMENT DISORDERS, PAIN | Journal of neurology, neurosurgery, and psychiatry |
| Orthostatic hypotension, cognition and structural brain imaging in hemodynamically impaired patients. | Starmans NLP, Wolters FJ, Leeuwis AE, Bron EE, de Bresser J, Brunner-La Rocca HP, Staals J, Muller M, Biessels GJ, Kappelle LJ | 2024-06-15 | Atrophy, Blood pressure, Cerebral small vessel disease, Cognition, Orthostatic hypotension, White matter hyperintensities | Journal of the neurological sciences |
| Differences in characteristics and outcomes of older patients hospitalized for COVID-19 after introduction of vaccination. | Smits RAL, van Raaij BFM, Trompet S, van der Linden CMJ, van der Bol JM, Jansen SWM, Polinder-Bos HA, Willems HC, van de Glind EMM, Minnema J, Tap L, Mooijaart SP | 2024-06-11 | COVID-19, Frailty, In-hospital mortality, Older patient, Vaccination | European geriatric medicine |
| Preparing for future pandemics: frailty associates with mortality in hospitalised older people during the entire COVID-19 pandemic, a Dutch multicentre cohort study. | van Raaij BFM, Noordam R, Smits RAL, van der Klei VMGTH, Jansen SWM, van der Linden CMJ, Polinder-Bos HA, Minnema J, Tap L, van der Bol JM, van de Glind EMM, Willems HC, van Deudekom FJA, Ruiter R, van Munster BC, Robben SHM, Schouten HJ, Barten DG, Lucke JA, Peeters G, Trompet S, Drewes YM, van den Bos F, Gussekloo J, Mooijaart SP | 2024-06-07 | COVID-19, Frailty, In-hospital mortality | European geriatric medicine |
| A plant-based diet index to study the relation between diet and disease risk among adults: a narrative review. | Schorr KA, Agayn V, de Groot LCPGM, Slagboom PE, Beekman M | 2024-06-01 | Age-related diseases, Cardiovascular disease, Nutritional epidemiology, Plant-based diet, Type 2 diabetes | The journal of nutrition, health & aging |
| Unraveling interindividual variation of trimethylamine N-oxide and its precursors at the population level. | Andreu-Sánchez S, Ahmad S, Kurilshikov A, Beekman M, Ghanbari M, van Faassen M, van den Munckhof ICL, Steur M, Harms A, Hankemeier T, Ikram MA, Kavousi M, Voortman T, Kraaij R, Netea MG, Rutten JHW, Riksen NP, Zhernakova A, Kuipers F, Slagboom PE, van Duijn CM, Fu J, Vojinovic D | 2024-06-01 | TMAO, diet, genetics, gut microbiome, meta‐analysis, population cohort | iMeta |
| No evidence linking sleep traits with white blood cell counts: Multivariable-adjusted and Mendelian randomization analyses. | Noordam R, Ao L, Stroo JF, Willems van Dijk K, van Heemst D | 2024-06-01 | Mendelian randomization, sleep, white blood cells | European journal of clinical investigation |
| Variations over time in mode of birth and perinatal outcomes in women with one previous cesarean in the Netherlands: A 20-year population-based study. | Koorn I, Vis LC, Verschueren KJC, Rosman AN, van den Akker T | 2024-06-01 | cesarean birth, obstetrics, vaginal birth after cesarean | Birth (Berkeley, Calif.) |
| The influence of chorioamnionitis on respiratory drive and spontaneous breathing of premature infants at birth: a narrative review. | Panneflek TJR, Kuypers KLAM, Polglase GR, Derleth DP, Dekker J, Hooper SB, van den Akker T, Pas ABT | 2024-06-01 | Breathing, Chorioamnionitis, Inflammation, Neonatology, Resuscitation | European journal of pediatrics |
| Nephrology-tailored geriatric assessment as decision-making tool in kidney failure. | Berkhout-Byrne NC, Voorend CGN, Meuleman Y, Mooijaart SP, Brunsveld-Reinders AH, Bos WJW, Van Buren M | 2024-06-01 | geriatric assessment, kidney failure, kidney replacement therapy, older patients, shared decision‐making | Journal of renal care |
| Patient-Reported Satisfaction with Thyroid Hormone Replacement Therapy for Subclinical Hypothyroidism in Older Adults: A Pooled Analysis of Individual Participant Data from Two Randomized Controlled Trials. | Ravensberg J, Poortvliet RKE, Du Puy R, Rodondi N, Blum M, Kearney P, McCarthy VJC, Quinn T, Dekkers O, Jukema W, Mooijaart S, Gussekloo J | 2024-06-01 | aged, humans, patient satisfaction, randomized controlled trial, subclinical hypothyroidism, thyroxine | Thyroid : official journal of the American Thyroid Association |
| [Not Available]. | Van Asbroeck S, Köhler S, van Boxtel MPJ, Lipnicki DM, Crawford JD, Castro-Costa E, Lima-Costa MF, Blay SL, Shifu X, Wang T, Yue L, Lipton RB, Katz MJ, Derby CA, Guerchet M, Preux PM, Mbelesso P, Norton J, Ritchie K, Skoog I, Najar J, Sterner TR, Scarmeas N, Yannakoulia M, Dardiotis T, Rolandi E, Davin A, Rossi M, Gureje O, Ojagbemi A, Bello T, Kim KW, Han JW, Oh DJ, Trompet S, Gussekloo J, Riedel-Heller SG, Röhr S, Pabst A, Shahar S, Rivan NFM, Singh DKA, Jacobsen E, Ganguli M, Hughes T, Haan M, Aiello AE, Ding D, Zhao Q, Xiao Z, Narazaki K, Chen T, Chen S, Ng TP, Gwee X, Gao Q, Brodaty H, Trollor J, Kochan N, Lobo A, Santabárbara J, Gracia-Garcia P, Sachdev PS, Deckers K | 2024-06-01 | age, dementia, dementia risk reduction, education, effect modification, ethnicity, individual participant data meta‐analysis, interaction, lifestyle, primary prevention, region, risk factor, risk personalization, sex, socioeconomic | Alzheimer's & dementia : the journal of the Alzheimer's Association |
| A systematic review of subclinical hyperthyroidism guidelines: a remarkable range of recommendations. | Ursem SR, Boelen A, Bruinstroop E, Elders PJM, Gussekloo J, Poortvliet RKE, Heijboer AC, den Elzen WPJ | 2024-06-01 | clinical practice guideline, general practice, guideline, primary care, subclinical hyperthyroidism, systematic review, thyroid | European thyroid journal |
| Movement Patterns in Older Adults Recovering From Hip Fracture. | Kraaijkamp JJM, Stijntjes M, De Groot JH, Chavannes NH, Achterberg WP, van Dam van Isselt EF | 2024-06-01 | accelerometer, geriatric rehabilitation, sedentary behavior | Journal of aging and physical activity |
| Implementation of an Advance Care Planning Intervention in Nursing Homes: An International Multiple Case Study. | Brazil K, Walshe C, Doherty J, Harding AJE, Preston N, Bavelaar L, Cornally N, Di Giulio P, Gonella S, Hartigan I, Henderson C, Kaasalainen S, Loucka M, Sussman T, Vlckova K, van der Steen JT | 2024-06-01 | Comfort care, Decision-making, Dementia, Family caregiver | The Gerontologist |
| Does higher performance in a national licensing examination predict better quality of care? A longitudinal observational study of Ethiopian anesthetists. | Asemu YM, Yigzaw T, Desta FA, Scheele F, van den Akker T | 2024-05-27 | Anesthetists, Associate clinicians, Licensing examination, Patient outcome, Quality of care | BMC anesthesiology |
| Maternal thyroid function in early pregnancy and offspring school performance and neurodevelopmental disorders. | Møllehave LT, Grand MK, Kriegbaum M, Andersen CL, Lind BS, van Vliet NA, van Heemst D, Strandberg-Larsen K | 2024-05-24 | attention deficit hyperactivity disorder, autism spectrum disorder, neurodevelopment, pregnancy, thyroid function | The Journal of clinical endocrinology and metabolism |
| Author Correction: Prospective individual patient data meta-analysis of two randomized trials on convalescent plasma for COVID-19 outpatients. | Millat-Martinez P, Gharbharan A, Alemany A, Rokx C, Geurtsvankessel C, Papageorgiou G, van Geloven N, Jordans C, Groeneveld G, Swaneveld F, van der Schoot E, Corbacho-Monné M, Ouchi D, Piccolo Ferreira F, Malchair P, Videla S, García García V, Ruiz-Comellas A, Ramírez-Morros A, Rodriguez Codina J, Amado Simon R, Grifols JR, Blanco J, Blanco I, Ara J, Bassat Q, Clotet B, Baro B, Troxel A, Zwaginga JJ, Mitjà O, Rijnders BJA | 2024-05-22 | Nature communications | |
| Plasma trimethylamine N-oxide (TMAO): associations with cognition, neuroimaging, and dementia. | Yaqub A, Vojinovic D, Vernooij MW, Slagboom PE, Ghanbari M, Beekman M, van der Grond J, Hankemeier T, van Duijn CM, Ikram MA, Ahmad S | 2024-05-20 | Cognition, Dementia, Gut-microbiome, Metabolites, Neuroimaging, Population-based | Alzheimer's research & therapy |
| Knee-to-chest flexion manoeuvre to reduce respiratory distress after planned caesarean birth: a feasibility study. | Shirima FL, Keus A, Mmbaga BT, Hooper SB, Mchome B, Pyuza JJ, Van Den Akker T, Te Pas AB | 2024-05-06 | Neonatology, Respiratory Medicine | Archives of disease in childhood. Fetal and neonatal edition |
| Determinants of behaviors influencing implementation of maternal and perinatal death surveillance and response in low- and middle-income countries: A systematic review of qualitative studies. | Willcox ML, Okello IA, Maidwell-Smith A, Tura AK, van den Akker T, Knight M, Dumont A, Muller I | 2024-05-01 | behavioral factors, implementation, intervention planning, low‐ and middle‐income countries, maternal and perinatal death surveillance and review (MPDSR), qualitative, systematic review | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics |
| Efficacy and Safety Analyses of Recombinant Factor VIIa in Severe Post-Partum Hemorrhage. | Caram-Deelder C, McKinnon Edwards H, Zdanowicz JA, van den Akker T, Birkegård C, Blatný J, van der Bom JG, Colucci G, van Duuren D, van Geloven N, Henriquez DDCA, Knight M, Korsholm L, Landorph A, Lavigne Lissalde G, McQuilten ZK, Surbek D, Wellard C, Wood EM, Mercier FJ | 2024-05-01 | coagulants, delivery, hematologic, maternal mortality, obstetric, post-partum hemorrhage, pregnancy complications, recombinant activated factor VII, therapeutic use, thromboembolic events | Journal of clinical medicine |
| Geriatric Assessment in CKD Care: An Implementation Study. | Voorend CGN, Berkhout-Byrne NC, van Bodegom-Vos L, Diepenbroek A, Franssen CFM, Joosten H, Mooijaart SP, Bos WJW, van Buren M | 2024-05-01 | Chronic kidney disease, feasibility studies, geriatric assessment, implementation science, older people, shared decision making | Kidney medicine |
| Toxicity in Older Patients with Cancer Receiving Immunotherapy: An Observational Study. | Tran Van Hoi E, Trompet S, Van Holstein Y, Van Den Bos F, Van Heemst D, Codrington H, Labots G, Lohman S, Ozkan A, Portielje J, Mooijaart SP, De Glas NA, Derks M | 2024-05-01 | Drugs & aging | |
| Older people’s goals of care in relation to frailty status-the COOP-study. | van der Klei VMGTH, Drewes YM, van Raaij BFM, van Dalsen MDW, Julien AG, Festen J, Polinder-Bos H, Mooijaart SP, Gussekloo J, van den Bos F | 2024-05-01 | decision-making, health outcome prioritisation, older people, patient and public involvement, patient preference | Age and ageing |
| Sporadic cerebral small vessel disease and cognitive decline in healthy older adults: A systematic review and meta-analysis. | Jansma A, de Bresser J, Schoones JW, van Heemst D, Akintola AA | 2024-05-01 | Cognitive decline, MRI, cerebral small vessel disease, meta-analysis, older adults | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism |
| Impact of Pain and Neuropsychiatric Symptoms on Activities in Nursing Home Residents (COSMOS Trial). | van de Beek SH, Erdal A, Husebø BS, Vislapuu M, Achterberg WP, Caljouw MAA | 2024-05-01 | COSMOS study, Dementia, activity, behavior, nursing homes, pain | Journal of the American Medical Directors Association |
| Post-COVID-19 patients in geriatric rehabilitation substantially recover in daily functioning and quality of life. | van Tol LS, Haaksma ML, Cesari M, Dockery F, Everink IHJ, Francis BN, Gordon AL, Grund S, Matchekhina L, Bazan LMP, Schols JMGA, Topinková E, Vassallo MA, Caljouw MAA, Achterberg WP | 2024-05-01 | COVID-19, geriatric rehabilitation, older people, recovery | Age and ageing |
| Relocating within and between nursing homes during infectious disease outbreaks: A focus group study. | Broekharst DSE, Stoop A, Caljouw MAA, Achterberg WP | 2024-05-01 | COVID‐19, epidemics, infectious disease outbreaks, pandemics, relocations | Health science reports |
| Frailty Screening is Associated with Hospitalization and Decline in Quality of Life and Functional Status in Older Patients with Inflammatory Bowel Disease. | Asscher VER, Rodriguez Gírondo M, Fens J, Waars SN, Stuyt RJL, Baven-Pronk AMC, Srivastava N, Jacobs RJ, Haans JJL, Meijer LJ, Klijnsma-Slagboom JD, Duin MH, Peters MER, Lee-Kong FVYL, Provoost NE, Tijdeman F, van Dijk KT, Wieland MWM, Verstegen MGM, van der Meijs ME, Maan ADI, van Deudekom FJ, van der Meulen-de Jong AE, Mooijaart SP, Maljaars PWJ | 2024-04-23 | Crohn’s disease, elderly, functional decline, geriatric screening, ulcerative colitis | Journal of Crohn's & colitis |
| Active involvement in scientific research of persons living with dementia and long-term care users: a systematic review of existing methods with a specific focus on good practices, facilitators and barriers of involvement. | Groothuijse JM, van Tol LS, Leeuwen CCMTH, van Delden JJM, Caljouw MAA, Achterberg WP | 2024-04-09 | Dementia, Involvement in research, Long-term care, Methods, Older residents, Review | BMC geriatrics |
| Identification of Distinct Brain MRI Phenotypes and Their Association With Long-Term Dementia Risk in Community-Dwelling Older Adults | Keller JA, Sigurdsson S, Schmitz Abecassis B, Kant IM, Van Buchem MA, Launer LJ, van Osch MJ, Gudnason V, de Bresser J | 2024-04-09 | Neurology | |
| Associations of circulating GDF15 with combined cognitive frailty and depression in older adults of the MARK-AGE study. | Kochlik B, Herpich C, Moreno-Villanueva M, Klaus S, Müller-Werdan U, Weinberger B, Fiegl S, Toussaint O, Debacq-Chainiaux F, Schön C, Bernhard J, Breusing N, Gonos ES, Franceschi C, Capri M, Sikora E, Hervonen A, Hurme M, Slagboom PE, Dollé MET, Jansen E, Grune T, Bürkle A, Norman K | 2024-04-01 | Aging, Biomarker, Cognitive frailty, Depression, GDF15 | GeroScience |
| Genome-wide characterization of circulating metabolic biomarkers. | Karjalainen MK, Karthikeyan S, Oliver-Williams C, Sliz E, Allara E, Fung WT, Surendran P, Zhang W, Jousilahti P, Kristiansson K, Salomaa V, Goodwin M, Hughes DA, Boehnke M, Fernandes Silva L, Yin X, Mahajan A, Neville MJ, van Zuydam NR, de Mutsert R, Li-Gao R, Mook-Kanamori DO, Demirkan A, Liu J, Noordam R, Trompet S, Chen Z, Kartsonaki C, Li L, Lin K, Hagenbeek FA, Hottenga JJ, Pool R, Ikram MA, van Meurs J, Haller T, Milaneschi Y, Kähönen M, Mishra PP, Joshi PK, Macdonald-Dunlop E, Mangino M, Zierer J, Acar IE, Hoyng CB, Lechanteur YTE, Franke L, Kurilshikov A, Zhernakova A, Beekman M, van den Akker EB, Kolcic I, Polasek O, Rudan I, Gieger C, Waldenberger M, Asselbergs FW, Hayward C, Fu J, den Hollander AI, Menni C, Spector TD, Wilson JF, Lehtimäki T, Raitakari OT, Penninx BWJH, Esko T, Walters RG, Jukema JW, Sattar N, Ghanbari M, Willems van Dijk K, Karpe F, McCarthy MI, Laakso M, Järvelin MR, Timpson NJ, Perola M, Kooner JS, Chambers JC, van Duijn C, Slagboom PE, Boomsma DI, Danesh J, Ala-Korpela M, Butterworth AS, Kettunen J | 2024-04-01 | Nature | |
| Approaches to improve and adapt maternal mortality estimations in low- and middle-income countries: A scoping review. | Tholandi M, Zethof S, Kim YM, Tura AK, Ket J, Willcox M, van den Akker T, Ilozumba O | 2024-04-01 | community participation, data collection, developing countries, maternal death, maternal mortality, quality indicators | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics |
| Severe postpartum hemorrhage and the risk of adverse maternal outcome: A comparative analysis of two population-based studies in France and the Netherlands. | de Vries PLM, Deneux-Tharaux C, Caram-Deelder C, Goffinet F, Henriquez DDCA, Seco A, van der Bom JG, van den Akker T | 2024-04-01 | Clinical care, Cross-country studies, Management, Maternal morbidity, Maternal mortality, Obstetric hemorrhage, Severe maternal outcome | Preventive medicine reports |
| Prevalence of Frailty in European Emergency Departments (FEED): an international flash mob study. | 2024-04-01 | Emergency care, Frailty, Geriatrics | European geriatric medicine | |
| Older patients’ experiences with and attitudes towards an oncogeriatric pathway: A qualitative study. | Uit den Boogaard A, de Jongh D, van den Elst MJT, Trompet S, de Man-van Ginkel JM, Portielje JEA, Meuleman Y, Mooijaart SP, de Glas NA, van den Bos F | 2024-04-01 | Geriatric assessment, Geriatric oncology, Oncogeriatric care pathway, Patient experiences, Qualitative study | Journal of geriatric oncology |
| External validation of six COVID-19 prognostic models for predicting mortality risk in older populations in a hospital, primary care, and nursing home setting. | Zahra A, van Smeden M, Abbink EJ, van den Berg JM, Blom MT, van den Dries CJ, Gussekloo J, Wouters F, Joling KJ, Melis R, Mooijaart SP, Peters JB, Polinder-Bos HA, van Raaij BFM, Appelman B, la Roi-Teeuw HM, Moons KGM, Luijken K | 2024-04-01 | COVID-19, COVID-19-Related mortality, External validation, Older population, Prognostic models, clinical prediction models | Journal of clinical epidemiology |
| Structural disconnectivity in postoperative delirium: A perioperative two-center cohort study in older patients. | Fislage M, Winzeck S, Woodrow R, Lammers-Lietz F, Stamatakis EA, Correia MM, Preller J, Feinkohl I, Hendrikse J, Pischon T, Spies CD, Slooter AJC, Winterer G, Menon DK, Zacharias N | 2024-04-01 | brain health, dementia delirium interface, diffusion kurtosis imaging, postoperative delirium, structural disconnectivity, white matter abnormalities | Alzheimer's & dementia : the journal of the Alzheimer's Association |
| Future policy and research for advance care planning in dementia: consensus recommendations from an international Delphi panel of the European Association for Palliative Care | Nakanishi M, Martins Pereira S, Van den Block L, Parker D, Harrison-Dening K, Di Giulio P, In der Schmitten J, Larkin PJ, Mimica N, Sudore RL, Holmerová I, Korfage IJ, van der Steen JT | 2024-04-01 | The Lancet Healthy Longevity | |
| The role of genetically-influenced phospholipid transfer protein activity in lipoprotein metabolism and coronary artery disease. | Ao L, Noordam R, Rensen PCN, van Heemst D, Willems van Dijk K | 2024-03-29 | Coronary artery disease, Genetic risk score, Lipoprotein metabolism, Phospholipid transfer protein (PLTP) activity | Journal of clinical lipidology |
| The effect of paracetamol on care dependency and daily functioning in persons with advanced dementia living in long-term care facilities. | van Dam PH, Achterberg WP, Husebo BS, Caljouw MA | 2024-03-22 | Acetaminophen, Care dependency, Daily functioning, Dementia, Nursing home, Paracetamol, Quality of life | BMC geriatrics |
| Healthcare worker burnout: exploring the experiences of doctors working in a maternity unit in Namibia. | Brückner TY, Heemelaar S, Endjala T, van den Akker T | 2024-03-21 | Blame culture, Burnout, Healthcare worker, Maternal health, Support, Trauma | BMC health services research |
| Noninvasive monitoring technologies to identify discomfort and distressing symptoms in persons with limited communication at the end of life: a scoping review. | Xu J, Smaling HJA, Schoones JW, Achterberg WP, van der Steen JT | 2024-03-21 | Dementia, Information technology, Medical informatics, Palliative care | BMC palliative care |
| Factors influencing interprofessional collaboration in general and during multidisciplinary team meetings in long-term care and geriatric rehabilitation: a qualitative study. | Doornebosch AJ, Achterberg WP, Smaling HJA | 2024-03-15 | Barriers, Facilitators, Geriatric rehabilitation, Interprofessional collaboration, Long-term care, Multidisciplinary team meetings, Patient outcome measures | BMC medical education |
| Clarifying the biological and statistical assumptions of cross-sectional biological age predictors: an elaborate illustration using synthetic and real data. | Sluiskes MH, Goeman JJ, Beekman M, Slagboom PE, Putter H, Rodríguez-Girondo M | 2024-03-08 | Aging, Aging clocks, Aging divergence, Aging rate, Biological age, Cross-sectional biological age predictors, Klemera-Doubal | BMC medical research methodology |
| A Large-Scale Genome-Wide Study of Gene-Sleep Duration Interactions for Blood Pressure in 811,405 Individuals from Diverse Populations. | Nagarajan P, Winkler TW, Bentley AR, Miller CL, Kraja AT, Schwander K, Lee S, Wang W, Brown MR, Morrison JL, Giri A, O'Connell JR, Bartz TM, de Las Fuentes L, Gudmundsdottir V, Guo X, Harris SE, Huang Z, Kals M, Kho M, Lefevre C, Luan J, Lyytikäinen LP, Mangino M, Milaneschi Y, Palmer ND, Rao V, Rauramaa R, Shen B, Stadler S, Sun Q, Tang J, Thériault S, van der Graaf A, van der Most PJ, Wang Y, Weiss S, Westerman KE, Yang Q, Yasuharu T, Zhao W, Zhu W, Altschul D, Ansari MAY, Anugu P, Argoty-Pantoja AD, Arzt M, Aschard H, Attia JR, Bazzanno L, Breyer MA, Brody JA, Cade BE, Chen HH, Ida Chen YD, Chen Z, de Vries PS, Dimitrov LM, Do A, Du J, Dupont CT, Edwards TL, Evans MK, Faquih T, Felix SB, Fisher-Hoch SP, Floyd JS, Graff M, Gu C, Gu D, Hairston KG, Hanley AJ, Heid IM, Heikkinen S, Highland HM, Hood MM, Kähönen M, Karvonen-Gutierrez CA, Kawaguchi T, Kazuya S, Kelly TN, Komulainen P, Levy D, Lin HJ, Liu PY, Marques-Vidal P, McCormick JB, Mei H, Meigs JB, Menni C, Nam K, Nolte IM, Pacheco NL, Petty LE, Polikowsky HG, Province MA, Psaty BM, Raffield LM, Raitakari OT, Rich SS, Riha RL, Risch L, Risch M, Ruiz-Narvaez EA, Scott RJ, Sitlani CM, Smith JA, Sofer T, Teder-Laving M, Völker U, Vollenweider P, Wang G, van Dijk KW, Wilson OD, Xia R, Yao J, Young KL, Zhang R, Zhu X, Below JE, Böger CA, Conen D, Cox SR, Dörr M, Feitosa MF, Fox ER, Franceschini N, Gharib SA, Gudnason V, Harlow SD, He J, Holliday EG, Kutalik Z, Lakka TA, Lawlor DA, Lee S, Lehtimäki T, Li C, Liu CT, Mägi R, Matsuda F, Morrison AC, Penninx BW, Peyser PA, Rotter JI, Snieder H, Spector TD, Wagenknecht LE, Wareham NJ, Zonderman AB, North KE, Fornage M, Hung AM, Manning AK, Gauderman J, Chen H, Munroe PB, Rao DC, van Heemst D, Redline S, Noordam R, Wang H | 2024-03-08 | medRxiv : the preprint server for health sciences | |
| Physiological-based cord clamping in very preterm infants: the Aeration, Breathing, Clamping 3 (ABC3) trial-statistical analysis plan for a multicenter randomized controlled trial. | Willemsen SP, Knol R, Brouwer E, van den Akker T, DeKoninck PLJ, Lopriore E, Onland W, de Boode WP, van Kaam AH, Nuytemans DH, Reiss IKM, Hutten GJ, Prins SA, Mulder EEM, Hulzebos CV, van Sambeeck SJ, van der Putten ME, Zonnenberg IA, Te Pas AB, Vermeulen MJ | 2024-03-04 | Cord clamping, Physiological-based cord clamping, Preterm infants, Randomized clinical trial, Statistical Analysis Plan | Trials |
| Monoclonal RhD prophylaxis: high time to evaluate efficacy. | Verweij E, Tura AK, Gure T, Pyuza J, Mchome B, Kawaza K, Moons P, de Winter D, Van't Oever R, Spitalnik S, van der Schoot CE, van den Akker T | 2024-03-02 | Lancet (London, England) | |
| The impact of the COVID-19 pandemic on Positive Health among older adults in relation to the complexity of health problems. | van der Klei VMGTH, Moens IS, Simons T, den Elzen WPJ, Mooijaart SP, Gussekloo J, Trompet S, Drewes YM | 2024-03-01 | COVID-19, community-dwelling, health impact assessment, older adults, self-rated health | Journal of the American Geriatrics Society |
| Aetiology and use of antibiotics in pregnancy-related infections: results of the WHO Global Maternal Sepsis Study (GLOSS), 1-week inception cohort. | Ribeiro-do-Valle CC, Bonet M, Brizuela V, Abalos E, Baguiya A, Bellissimo-Rodrigues F, Budianu M, Puscasiu L, Knight M, Lissauer D, Dunlop C, Jacob ST, Shakoor S, Gadama L, Assarag B, Souza JP, Cecatti JG | 2024-02-24 | Antibiotic, Infections, Maternal morbidity, Maternal sepsis | Annals of clinical microbiology and antimicrobials |
| Limited incremental predictive value of the frailty index and other vulnerability measures from routine care data for mortality risk prediction in older patients with COVID-19 in primary care. | la Roi-Teeuw HM, Luijken K, Blom MT, Gussekloo J, Mooijaart SP, Polinder-Bos HA, van Smeden M, Geersing GJ, van den Dries CJ | 2024-02-23 | COVID-19, Frailty, Multiple imputation, Older people, Primary care, Prognosis research, Prognostic factor study, Regression modelling, Vulnerability | BMC primary care |
| Incidence and Determinants of Spontaneous Normalization of Subclinical Hypothyroidism in Older Adults. | van der Spoel E, van Vliet NA, Poortvliet RKE, Du Puy RS, den Elzen WPJ, Quinn TJ, Stott DJ, Sattar N, Kearney PM, Blum MR, Alwan H, Rodondi N, Collet TH, Westendorp RGJ, Ballieux BE, Jukema JW, Dekkers OM, Gussekloo J, Mooijaart SP, van Heemst D | 2024-02-20 | follow-up studies, older adults, subclinical hypothyroidism, thyrotropin | The Journal of clinical endocrinology and metabolism |
| Deficits in geriatric assessment are important in relation to fatigue in older patients with Inflammatory Bowel Disease. | Fons AB, Asscher VER, Stuyt RJL, Baven-Pronk AMC, van der Marel S, Jacobs RJ, Mooijaart SP, Eikelenboom P, van der Meulen-de Jong AE, Kalisvaart KJ, Jeroen Maljaars PW | 2024-02-17 | Crohn's disease, Elderly, Ulcerative colitis | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver |
| Prioritising actions to address stagnating maternal mortality rates globally. | van den Akker T, D'Souza R, Tura AK, Nair M, Engjom H, Knight M, Donati S | 2024-02-03 | Lancet (London, England) | |
| Validation of biomarkers of aging. | Moqri M, Herzog C, Poganik JR, Ying K, Justice JN, Belsky DW, Higgins-Chen AT, Chen BH, Cohen AA, Fuellen G, Hägg S, Marioni RE, Widschwendter M, Fortney K, Fedichev PO, Zhavoronkov A, Barzilai N, Lasky-Su J, Kiel DP, Kennedy BK, Cummings S, Slagboom PE, Verdin E, Maier AB, Sebastiano V, Snyder MP, Gladyshev VN, Horvath S, Ferrucci L | 2024-02-01 | Nature medicine | |
| Comprehensive evaluation of smoking exposures and their interactions on DNA methylation. | Hoang TT, Lee Y, McCartney DL, Kersten ETG, Page CM, Hulls PM, Lee M, Walker RM, Breeze CE, Bennett BD, Burkholder AB, Ward J, Brantsæter AL, Caspersen IH, Motsinger-Reif AA, Richards M, White JD, Zhao S, Richmond RC, Magnus MC, Koppelman GH, Evans KL, Marioni RE, Håberg SE, London SJ | 2024-02-01 | Dietary intake, Epigenomics, Illumina EPIC array, Secondhand smoke exposure, Sex difference, Smoking cessation | EBioMedicine |
| Characteristics and outcomes of pregnant women hospitalized with severe maternal outcomes in eastern Ethiopia: Results from the Ethiopian Obstetric Surveillance System study. | Tura AK, Knight M, Girma S, Ahmed R, Yuya M, Bekele D, Hassen TA, Stekelenburg J, van den Akker T | 2024-02-01 | Ethiopia, audit, maternal mortality, severe maternal morbidity, surveillance | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics |
| Compliance with maternal sepsis guidelines in a tertiary hospital in the Netherlands. | de Vries BS, Verschueren KJC, Jansen S, Bekker V, Veenhof MB, van den Akker T | 2024-02-01 | Maternal sepsis, early warning score, rapid response team, sepsis management, sepsis prevention, surviving sepsis campaign | Hospital practice (1995) |
| Geriatric predictors of response and adverse events in older patients with cancer treated with immune checkpoint inhibitors: A systematic review. | Özkan A, van den Bos F, Mooijaart SP, Slingerland M, Kapiteijn E, de Miranda NFCC, Portielje JEA, de Glas NA | 2024-02-01 | Frailty, Geriatric oncology, Geriatric screening, Geriatric syndromes, Immune checkpoint inhibitors, Immunosenescence, Older patients, Overall survival, Systematic review, Toxicity | Critical reviews in oncology/hematology |
| Apathy Symptoms, Physical and Cognitive Function, Health-Related Quality of Life, and Mortality in Older Patients With CKD: A Longitudinal Observational Study. | Voorend CGN, van Buren M, Berkhout-Byrne NC, Kerckhoffs APM, van Oevelen M, Gussekloo J, Richard E, Bos WJW, Mooijaart SP | 2024-02-01 | Apathy, cognitive dysfunction, end-stage kidney disease, frailty, geriatric assessment | American journal of kidney diseases : the official journal of the National Kidney Foundation |
| The trajectory of pain and pain intensity in the upper extremity after stroke over time: a prospective study in a rehabilitation population. | van Meijeren-Pont W, Arwert H, Volker G, Fiocco M, Achterberg WP, Vliet Vlieland TPM, Oosterveer DM | 2024-02-01 | Stroke, pain, pain intensity, rehabilitation, upper extremity pain | Disability and rehabilitation |
| Diagnostic accuracy of urine biomarkers for urinary tract infection in older women: a case-control study. | Bilsen MP, Treep MM, Aantjes MJ, van Andel E, Stalenhoef JE, van Nieuwkoop C, Leyten EMS, Delfos NM, van Uhm JIM, Sijbom M, Akintola AA, Numans ME, Achterberg WP, Mooijaart SP, van der Beek MT, Cobbaert CM, Conroy SP, Visser LG, Lambregts MMC | 2024-02-01 | Antimicrobial stewardship, Asymptomatic bacteriuria, Biomarkers, Diagnostic accuracy, Older patients, Urinary tract infection | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases |
| Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications. | Sterenborg RBTM, Steinbrenner I, Li Y, Bujnis MN, Naito T, Marouli E, Galesloot TE, Babajide O, Andreasen L, Astrup A, Åsvold BO, Bandinelli S, Beekman M, Beilby JP, Bork-Jensen J, Boutin T, Brody JA, Brown SJ, Brumpton B, Campbell PJ, Cappola AR, Ceresini G, Chaker L, Chasman DI, Concas MP, Coutinho de Almeida R, Cross SM, Cucca F, Deary IJ, Kjaergaard AD, Echouffo Tcheugui JB, Ellervik C, Eriksson JG, Ferrucci L, Freudenberg J, Fuchsberger C, Gieger C, Giulianini F, Gögele M, Graham SE, Grarup N, Gunjača I, Hansen T, Harding BN, Harris SE, Haunsø S, Hayward C, Hui J, Ittermann T, Jukema JW, Kajantie E, Kanters JK, Kårhus LL, Kiemeney LALM, Kloppenburg M, Kühnel B, Lahti J, Langenberg C, Lapauw B, Leese G, Li S, Liewald DCM, Linneberg A, Lominchar JVT, Luan J, Martin NG, Matana A, Meima ME, Meitinger T, Meulenbelt I, Mitchell BD, Møllehave LT, Mora S, Naitza S, Nauck M, Netea-Maier RT, Noordam R, Nursyifa C, Okada Y, Onano S, Papadopoulou A, Palmer CNA, Pattaro C, Pedersen O, Peters A, Pietzner M, Polašek O, Pramstaller PP, Psaty BM, Punda A, Ray D, Redmond P, Richards JB, Ridker PM, Russ TC, Ryan KA, Olesen MS, Schultheiss UT, Selvin E, Siddiqui MK, Sidore C, Slagboom PE, Sørensen TIA, Soto-Pedre E, Spector TD, Spedicati B, Srinivasan S, Starr JM, Stott DJ, Tanaka T, Torlak V, Trompet S, Tuhkanen J, Uitterlinden AG, van den Akker EB, van den Eynde T, van der Klauw MM, van Heemst D, Verroken C, Visser WE, Vojinovic D, Völzke H, Waldenberger M, Walsh JP, Wareham NJ, Weiss S, Willer CJ, Wilson SG, Wolffenbuttel BHR, Wouters HJCM, Wright MJ, Yang Q, Zemunik T, Zhou W, Zhu G, Zöllner S, Smit JWA, Peeters RP, Köttgen A, Teumer A, Medici M | 2024-01-30 | Nature communications | |
| Differences in rates of severe perineal trauma between midwife-led and obstetrician-led care in the Netherlands: A nationwide cohort study. | Seijmonsbergen-Schermers AE, Peerdeman KM, van den Akker T, Titulaer LM, Roovers JP, Peters LL, Verhoeven CJ, de Jonge A | 2024-01-30 | Care providers, Interventions, Maternity care setting, OASI, Obstetric anal sphincter injury, Place of birth, Risk factors, SPT, Severe perineal trauma | Heliyon |
| Inequalities in use of hospitals for childbirth among rural women in sub-Saharan Africa: a comparative analysis of 18 countries using Demographic and Health Survey data. | Straneo M, Hanson C, van den Akker T, Afolabi BB, Asefa A, Delamou A, Dennis M, Gadama L, Mahachi N, Mlilo W, Pembe AB, Tsuala Fouogue J, Beňová L | 2024-01-22 | Epidemiology, Health systems, Maternal health, Obstetrics | BMJ global health |
| Incidence and determinants of perinatal mortality in five urban hospitals in Dar es Salaam, Tanzania: a cohort study with an embedded case-control analysis. | Sequeira Dmello B, John TW, Housseine N, Meyrowitsch DW, van Roosmalen J, van den Akker T, Kujabi ML, Festo C, Nkungu D, Muniro Z, Kabanda I, Msumi R, Maembe L, Sangalala M, Hyera E, Lema J, Bayongo S, Mshiu J, Kidanto HL, Maaløe N | 2024-01-13 | CCBRT, Dar es Salaam, Hypertensive disorders in pregnancy, Neonatal deaths, PartoMa, Perinatal deaths, Quality of care, Stillbirths, Tanzania, Urban health | BMC pregnancy and childbirth |
| An exploration of relocation initiatives deployed within and between nursing homes: a qualitative study. | Broekharst DSE, Stoop A, Achterberg WP, Caljouw MAA | 2024-01-04 | Bridging initiatives, Nursing homes, Older adults, Post-relocation initiatives, Pre-relocation initiatives, Relocation initiatives | BMC health services research |
| The ageing thyroid: implications for longevity and patient care. | van Heemst D | 2024-01-01 | Nature reviews. Endocrinology | |
| Association of Biological Age with Tumor Microenvironment in Patients with Esophageal Adenocarcinoma. | Ravensbergen C, van Holstein Y, Hagenaars S, Crobach S, Trompet S, Portielje J, de Glas N, van Heemst D, van den Bos F, Tollenaar R, Mesker W, Mooijaart S, Slingerland M | 2024-01-01 | Biological age, Esophageal cancer, Frailty, Geriatric assessment, Tumor microenvironment | Gerontology |
| Experiences of community health workers on adopting mHealth in rural Malawi: A qualitative study. | Kachimanga C, Mulwafu M, Ndambo MK, Harare J, Murkherjee J, Kulinkina AV, Mbae S, Ndarama E, van den Akker T, Abejirinde IO | 2024-01-01 | Malawi, community health workers, mHealth, maternal health | Digital health |
| HIV seroconversion among female sex workers: retrospective cohort study from a large-scale HIV prevention and sexual and reproductive health program in Tanzania. | Mbita G, Mwanamsangu A, Komba AN, Casalini C, Luponya M, Curran K, Christensen A, Kim YM, Reed J, Makyao N, Kategile U, Conserve DF, van Roosmalen J, van den Akker T | 2024-01-01 | HIV seroconversion, HIV/AIDS (acquired immunodeficiency syndrome), Tanzania, female sex workers (FSWs), key populations | Frontiers in reproductive health |
| What are best practices for involving family caregivers in interventions aimed at responsive behaviour stemming from unmet needs of people with dementia in nursing homes: a scoping review. | Tasseron-Dries PEM, Smaling HJA, Nakanishi M, Achterberg WP, van der Steen JT | 2023-12-07 | Dementia, PALLIATIVE CARE, QUALITATIVE RESEARCH, Quality of Life | BMJ open |
| Inconsistent definitions of labour progress and over-medicalisation cause unnecessary harm during birth. | Maaløe N, Kujabi ML, Nathan NO, Skovdal M, Dmello BS, Wray S, van den Akker T, Housseine N | 2023-12-06 | BMJ (Clinical research ed.) | |
| Postpartum haemorrhage in high-resource settings: Variations in clinical management and future research directions based on a comparative study of national guidelines. | de Vries PLM, Deneux-Tharaux C, Baud D, Chen KK, Donati S, Goffinet F, Knight M, D'Souzah R, Sueters M, van den Akker T | 2023-12-01 | clinical guidelines, obstetric haemorrhage, postpartum haemorrhage | BJOG : an international journal of obstetrics and gynaecology |
| Spontaneous haemoperitoneum in pregnancy: Nationwide surveillance and Delphi audit system. | Schreurs AMF, Overtoom EM, de Boer MA, van der Houwen LEE, Lier MCI, van den Akker T, Cornette J, Vogelvang TE, Beenakkers ICM, Rosman AN, Maas JWM, Heineman DJ, Finken MJJ, de Vries JJJ, Burger NB, Schaap TP, Bloemenkamp KWM, Mijatovic V | 2023-12-01 | ART, NethOSS, SHiP, endometriosis, fetal morbidity, maternal morbidity, obstetric surveillance system | BJOG : an international journal of obstetrics and gynaecology |
| Prophylactic radiologic interventions to reduce postpartum hemorrhage in women with risk factors for placenta accreta spectrum disorder: a nationwide cohort study. | Bonsen LR, Harskamp V, Feddouli S, Bloemenkamp KWM, Duvekot JJ, Pors A, van Roosmalen J, Zwart JJ, van Lith JMM, Hendriks J, Urlings TAJ, van den Akker T, van der Bom JG, Henriquez DDCA | 2023-12-01 | Placenta accreta spectrum, maternal morbidity, postpartum hemorrhage, radiologic interventions | The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians |
| Confidential Enquiry into Maternal Deaths in Namibia, 2018-2019: A Local Approach to Strengthen the Review Process and a Description of Review Findings and Recommendations. | Heemelaar S, Callard B, Shikwambi H, Ellmies J, Kafitha W, Stekelenburg J, van den Akker T, Mackenzie S | 2023-12-01 | HIV, Maternal mortality, Namibia | Maternal and child health journal |
| White matter hyperintensity shape is associated with long-term dementia risk. | Keller JA, Sigurdsson S, Klaassen K, Hirschler L, van Buchem MA, Launer LJ, van Osch MJP, Gudnason V, de Bresser J | 2023-12-01 | cerebral small vessel disease, cognitive decline, dementia, magnetic resonance imaging, white matter hyperintensities | Alzheimer's & dementia : the journal of the Alzheimer's Association |
| Functioning and recovery during stroke rehabilitation: a comparison between pre-stroke frail and non-frail patients. | Mennema Å, Vliet Vlieland TPM, Achterberg WP, Oosterveer DM | 2023-12-01 | Frailty, Outcomes, Rehabilitation, Stroke | European geriatric medicine |
| Priority measures to prevent infections and maintain residents’ well-being during COVID-19 outbreaks in nursing homes: Consensus among staff and resident representatives determined in an online nominal group technique study. | van Tol LS, Smaling HJA, Janus SIM, Caljouw MAA, Achterberg WP | 2023-12-01 | COVID-19, Decision making, Infection prevention, Measures, Nursing homes, Policy making, Well-being | International journal of nursing studies advances |
| Technical Report: A Comprehensive Comparison between Different Quantification Versions of Nightingale Health’s 1H-NMR Metabolomics Platform. | Bizzarri D, Reinders MJT, Beekman M, Slagboom PE, van den Akker EB, On Behalf Of The BbmriNl | 2023-11-30 | NMR metabolomics, epidemiology, multivariate risk models, nightingale health, re-quantification | Metabolites |
| Facilitators and barriers of implementation of routine postnatal care guidelines for women: A systematic scoping review using critical interpretive synthesis. | Beňová L, Semaan A, Portela A, Bonet M, van den Akker T, Pembe AB, Moran A, Duclos D | 2023-11-24 | Journal of global health | |
| Consensus definition of advance care planning in dementia: A 33‐country Delphi study | van der Steen JT, Nakanishi M, Van den Block L, Di Giulio P, Gonella S, in der Schmitten J, Sudore RL, Harrison Dening K, Parker D, Mimica N, Holmerova I, Larkin P, Martins Pereira S, Rietjens JAC, Korfage IJ | 2023-11-20 | Alzheimer's & Dementia | |
| Identified senescence endotypes in aged cartilage are reflected in the blood metabolome | Boone I, Tuerlings M, Coutinho de Almeida R, Lehmann J, Ramos Y, Nelissen R, Slagboom E, de Keizer P, Meulenbelt I | 2023-11-14 | GeroScience | |
| Becoming a physician for older patients: exploring the professional identity formation of medical students during a nursing home clerkship. A qualitative study. | Moll-Jongerius A, Langeveld K, Helmich E, Masud T, Kramer AWM, Achterberg WP | 2023-11-07 | Clerkship, Community of practice, Medical students, Nursing home, Older persons, Professional identity formation | BMC medical education |
| Delirium in older patients with COVID-19: Prevalence, risk factors and clinical outcomes across the first three waves of the pandemic. | Minnema J, Tap L, van der Bol JM, van Deudekom FJA, Faes MC, Jansen SWM, van der Linden CMJ, Lucke JA, Mooijaart SP, van Munster B, Noordam R, van Raaij BFM, Ruiter R, Smits RAL, Willems HC, Mattace-Raso FUS, Polinder-Bos HA | 2023-11-01 | COVID-19, SARS-CoV-2, delirium, frailty, metabolic encephalopathy, older adults | International journal of geriatric psychiatry |
| Prevalence, Severity and Impact of Visuospatial Neglect in Geriatric Stroke Rehabilitation, a Cross-Sectional Study. | Bosma MS, Caljouw MAA, Achterberg WP, Nijboer TCW | 2023-11-01 | Geriatric rehabilitation, assessment, functional outcome, measurement, neglect, prevalence, severity, stroke | Journal of the American Medical Directors Association |
| Metabolomic biomarkers of habitual B vitamin intakes unveil novel differentially methylated positions in the human epigenome. | Costeira R, Evangelista L, Wilson R, Yan X, Hellbach F, Sinke L, Christiansen C, Villicaña S, Masachs OM, Tsai PC, Mangino M, Menni C, Berry SE, Beekman M, van Heemst D, Slagboom PE, Heijmans BT, Suhre K, Kastenmüller G, Gieger C, Peters A, Small KS, Linseisen J, Waldenberger M, Bell JT | 2023-10-19 | B vitamins, Biomarkers, DNA methylation, Diet, Folate, Metabolomics | Clinical epigenetics |
| Consequences of contact restrictions for long-term care residents during the first months of COVID-19 pandemic: a scoping review. | Benzinger P, Wahl HW, Bauer JM, Keilhauer A, Dutzi I, Maier S, Hölzer N, Achterberg WP, Denninger NE | 2023-10-17 | Care facility, Coronavirus, Health consequences, Loneliness, Nursing home, Quality of life | European journal of ageing |
| Epigenetic and Metabolomic Biomarkers for Biological Age: A Comparative Analysis of Mortality and Frailty Risk. | Kuiper LM, Polinder-Bos HA, Bizzarri D, Vojinovic D, Vallerga CL, Beekman M, Dollé ET, Ghanbari M, Voortman T, Reinders MJT, Verschuren WMM, Slagboom PE, van den Akker EB, van Meurs JBJ | 2023-10-09 | DNA methylation, Frailty, Mortality | The journals of gerontology. Series A, Biological sciences and medical sciences |
| [Ethnicity as a prognostic factor in extreme preterm birth]. | De Proost L, Van den Akker T, Haalboom F, Verweij EJ | 2023-10-04 | Nederlands tijdschrift voor geneeskunde | |
| Chemotherapy-Related Toxic Effects and Quality of Life and Physical Functioning in Older Patients. | Baltussen JC, de Glas NA, van Holstein Y, van der Elst M, Trompet S, Uit den Boogaard A, van der Plas-Krijgsman W, Labots G, Holterhues C, van der Bol JM, Mammatas LH, Liefers GJ, Slingerland M, van den Bos F, Mooijaart SP, Portielje JEA | 2023-10-02 | JAMA network open | |
| Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification. | Kavousi M, Bos MM, Barnes HJ, Lino Cardenas CL, Wong D, Lu H, Hodonsky CJ, Landsmeer LPL, Turner AW, Kho M, Hasbani NR, de Vries PS, Bowden DW, Chopade S, Deelen J, Benavente ED, Guo X, Hofer E, Hwang SJ, Lutz SM, Lyytikäinen LP, Slenders L, Smith AV, Stanislawski MA, van Setten J, Wong Q, Yanek LR, Becker DM, Beekman M, Budoff MJ, Feitosa MF, Finan C, Hilliard AT, Kardia SLR, Kovacic JC, Kral BG, Langefeld CD, Launer LJ, Malik S, Hoesein FAAM, Mokry M, Schmidt R, Smith JA, Taylor KD, Terry JG, van der Grond J, van Meurs J, Vliegenthart R, Xu J, Young KA, Zilhão NR, Zweiker R, Assimes TL, Becker LC, Bos D, Carr JJ, Cupples LA, de Kleijn DPV, de Winther M, den Ruijter HM, Fornage M, Freedman BI, Gudnason V, Hingorani AD, Hokanson JE, Ikram MA, Išgum I, Jacobs DR, Kähönen M, Lange LA, Lehtimäki T, Pasterkamp G, Raitakari OT, Schmidt H, Slagboom PE, Uitterlinden AG, Vernooij MW, Bis JC, Franceschini N, Psaty BM, Post WS, Rotter JI, Björkegren JLM, O'Donnell CJ, Bielak LF, Peyser PA, Malhotra R, van der Laan SW, Miller CL | 2023-10-01 | Nature genetics | |
| The impact of sociodemographic status on the association of classical cardiovascular risk factors with coronary artery disease: a stratified Mendelian randomization study. | Martens LG, van Hamersveld D, le Cessie S, Willems van Dijk K, van Heemst D, Noordam R | 2023-10-01 | Body mass index, Cardiovascular diseases, Coronary artery disease, Effect modification, Mendelian randomization, Socioeconomic status | Journal of clinical epidemiology |
| Habitual sleep quantity and quality and the risk of obesity: What’s the chicken, and what’s the egg? | Noordam R, van Heemst D | 2023-10-01 | Sleep medicine | |
| The optimal healthy ranges of thyroid function defined by the risk of cardiovascular disease and mortality: systematic review and individual participant data meta-analysis. | Xu Y, Derakhshan A, Hysaj O, Wildisen L, Ittermann T, Pingitore A, Abolhassani N, Medici M, Kiemeney LALM, Riksen NP, Dullaart RPF, Trompet S, Dörr M, Brown SJ, Schmidt B, Führer-Sakel D, Vanderpump MPJ, Muendlein A, Drexel H, Fink HA, Ikram MK, Kavousi M, Rhee CM, Bensenor IM, Azizi F, Hankey GJ, Iacoviello M, Imaizumi M, Ceresini G, Ferrucci L, Sgarbi JA, Bauer DC, Wareham N, Boelaert K, Bakker SJL, Jukema JW, Vaes B, Iervasi G, Yeap BB, Westendorp RGJ, Korevaar TIM, Völzke H, Razvi S, Gussekloo J, Walsh JP, Cappola AR, Rodondi N, Peeters RP, Chaker L | 2023-10-01 | The lancet. Diabetes & endocrinology | |
| Interventions that may increase control at the end of life in persons with dementia: the cross-cultural CONT-END acceptability study protocol and pilot-testing. | Smaling HJA, Jingyuan X, Nakanishi M, Shinan-Altman S, Mehr DR, Radbruch L, Gaertner J, Werner P, Achterberg WP, van der Steen JT | 2023-09-27 | Advance care planning, Assisted death, Dementia, End of life, Euthanasia, Palliative care, Technology | BMC palliative care |
| Maternal mortality is preventable in Lebanon: A case series of maternal deaths to identify lessons learned using the “Three Delays” model. | Rebeiz MC, El-Kak F, van den Akker T, Hamadeh R, McCall SJ | 2023-09-01 | COVID-19, amniotic fluid embolism, avoidable, hypertensive disorders, maternal mortality, postpartum hemorrhage, preventable, sepsis | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics |
| Binational confidential enquiry of maternal deaths due to postpartum hemorrhage in France and the Netherlands: Lessons learned through the perspective of a different context of care. | de Vries PLM, van den Akker T, Bloemenkamp KWM, Grossetti E, Rigouzzo A, Saucedo M, Verspyck E, Zwart J, Deneux-Tharaux C | 2023-09-01 | France, confidential enquiry into maternal deaths, maternal mortality, maternity care, obstetrics, postpartum hemorrhage, the Netherlands | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics |
| The association of blood biomarkers with treatment response and adverse health outcomes in older patients with solid tumors: A systematic review. | van Holstein Y, van den Berkmortel PJE, Trompet S, van Heemst D, van den Bos F, Roemeling-van Rhijn M, de Glas NA, Beekman M, Slagboom PE, Portielje JEA, Mooijaart SP, van Munster BC | 2023-09-01 | Blood biomarker, Geriatric oncology, Outcome, cancer | Journal of geriatric oncology |
| The Role of a Composite Fitness Score in the Association Between Low-Density Cholesterol and All-Cause Mortality in Older Adults: An Individual Patient Data Meta-Analysis. | van der Ploeg MA, Poortvliet RKE, Bogaerts JMK, van der Klei VMGTH, Kerse N, Rolleston A, Teh R, Robinson L, Jagger C, Arai Y, Shikimoto R, Abe Y, Blom JW, Drewes YM, Gussekloo J | 2023-08-27 | Activities of daily living, Cognition, Frailty, Grip strength, Oldest old | The journals of gerontology. Series A, Biological sciences and medical sciences |
| Effects of smoking on genome-wide DNA methylation profiles: A study of discordant and concordant monozygotic twin pairs. | van Dongen J, Willemsen G, de Geus EJC, Boomsma DI, Neale MC | 2023-08-10 | DNA methylation, discordant twins, epidemiology, epigenetics, genetics, genomics, global health, human, identical twins, twin study | eLife |
| Pulmonary oedema in the course of severe maternal outcome in South Africa: A cohort study combined with clinical audit. | Heitkamp A, Sandberg E, Moodley A, Burke J, van Roosmalen J, Gebhardt S, Vollmer L, de Vries JI, van den Akker T, Theron G | 2023-08-01 | South Africa, audit, high-risk pregnancy, obstetrics, pulmonary oedema, severe maternal outcome | Tropical medicine & international health : TM & IH |
| Sex differences in dementia risk and risk factors: Individual-participant data analysis using 21 cohorts across six continents from the COSMIC consortium. | Gong J, Harris K, Lipnicki DM, Castro-Costa E, Lima-Costa MF, Diniz BS, Xiao S, Lipton RB, Katz MJ, Wang C, Preux PM, Guerchet M, Gbessemehlan A, Ritchie K, Ancelin ML, Skoog I, Najar J, Sterner TR, Scarmeas N, Yannakoulia M, Kosmidis MH, Guaita A, Rolandi E, Davin A, Gureje O, Trompet S, Gussekloo J, Riedel-Heller S, Pabst A, Röhr S, Shahar S, Singh DKA, Rivan NFM, Boxtel MV, Köhler S, Ganguli M, Chang CC, Jacobsen E, Haan M, Ding D, Zhao Q, Xiao Z, Narazaki K, Chen T, Chen S, Ng TP, Gwee X, Numbers K, Mather KA, Scazufca M, Lobo A, De-la-Cámara C, Lobo E, Sachdev PS, Brodaty H, Hackett ML, Peters SAE, Woodward M | 2023-08-01 | data harmonization, dementia, diversity, risk factor, sex difference | Alzheimer's & dementia : the journal of the Alzheimer's Association |
| Measuring Pain in Aphasia: Validity and Reliability of the PACSLAC-D. | de Vries NJ, van der Steen JT, Achterberg WP, Smaling HJA | 2023-08-01 | Pain management nursing : official journal of the American Society of Pain Management Nurses | |
| Towards optimal use of antithrombotic therapy of people with cancer at the end of life: A research protocol for the development and implementation of the SERENITY shared decision support tool. | Goedegebuur J, Abbel D, Accassat S, Achterberg WP, Akbari A, Arfuch VM, Baddeley E, Bax JJ, Becker D, Bergmeijer B, Bertoletti L, Blom JW, Calvetti A, Cannegieter SC, Castro L, Chavannes NH, Coma-Auli N, Couffignal C, Edwards A, Edwards M, Enggaard H, Font C, Gava A, Geersing GJ, Geijteman ECT, Greenley S, Gregory C, Gussekloo J, Hoffmann I, Højen AA, van den Hout WB, Huisman MV, Jacobsen S, Jagosh J, Johnson MJ, Jørgensen L, Juffermans CCM, Kempers EK, Konstantinides S, Kroder AF, Kruip MJHA, Lafaie L, Langendoen JW, Larsen TB, Lifford K, van der Linden YM, Mahé I, Maiorana L, Maraveyas A, Martens ESL, Mayeur D, van Mens TE, Mohr K, Mooijaart SP, Murtagh FEM, Nelson A, Nielsen PB, Ording AG, Ørskov M, Pearson M, Poenou G, Portielje JEA, Raczkiewicz D, Rasmussen K, Trinks-Roerdink E, Schippers I, Seddon K, Sexton K, Sivell S, Skjøth F, Søgaard M, Szmit S, Trompet S, Vassal P, Visser C, van Vliet LM, Wilson E, Klok FA, Noble SIR | 2023-08-01 | Anticoagulants, Deprescriptions, Hemorrhage, Neoplasms, Palliative care, Thrombosis | Thrombosis research |
| Increasing number of long-lived ancestors marks a decade of healthspan extension and healthier metabolomics profiles. | van den Berg N, Rodríguez-Girondo M, van Dijk IK, Slagboom PE, Beekman M | 2023-07-27 | Nature communications | |
| Preoperative thalamus volume is not associated with preoperative cognitive impairment (preCI) or postoperative cognitive dysfunction (POCD). | Fislage M, Feinkohl I, Borchers F, Pischon T, Spies CD, Winterer G, Zacharias N | 2023-07-20 | Scientific reports | |
| eHealth in Geriatric Rehabilitation: An International Survey of the Experiences and Needs of Healthcare Professionals. | Kraaijkamp JJM, Persoon A, Aurelian S, Bachmann S, Cameron ID, Choukou MA, Dockery F, Eruslanova K, Gordon AL, Grund S, Kim H, Maier AB, Pérez Bazan LM, Pompeu JE, Topinkova E, Vassallo MA, Chavannes NH, Achterberg WP, Van Dam van Isselt EF | 2023-07-05 | barriers and facilitators, eHealth, geriatric rehabilitation, implementation, information needs | Journal of clinical medicine |
| Hepatic triglyceride content is intricately associated with numerous metabolites and biochemical pathways. | Faquih TO, van Klinken JB, Li-Gao R, Noordam R, van Heemst D, Boone S, Sheridan PA, Michelotti G, Lamb H, de Mutsert R, Rosendaal FR, van Hylckama Vlieg A, van Dijk KW, Mook-Kanamori DO | 2023-07-01 | dysregulation, genetic targets, liver triglyceride content, metabolomics, pathway analysis | Liver international : official journal of the International Association for the Study of the Liver |
| Differential and sex- and age-specific risks of cardiometabolic diseases with unrelated metabolic syndrome dimensions. | Ao L, Willems van Dijk K, van Heemst D, Noordam R | 2023-07-01 | Obesity (Silver Spring, Md.) | |
| A novel approach for pharmacological substantiation of safety signals using plasma concentrations of medication and administrative/healthcare databases: A case study using Danish registries for an FDA warning on lamotrigine. | Wang W, Battini V, Carnovale C, Noordam R, van Dijk KW, Kragholm KH, van Heemst D, Soeorg H, Sessa M | 2023-07-01 | Lamotrigine, Mortality, Pharmacoepidemiology, Pharmacometrics | Pharmacological research |
| Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH. | Li JH, Brenner LN, Kaur V, Figueroa K, Schroeder P, Huerta-Chagoya A, Udler MS, Leong A, Mercader JM, Florez JC | 2023-07-01 | Genetics, Genome-wide association study, Glipizide, Incretin, Metformin, Multi-ancestry, Pathophysiology, Pharmacogenetics, Sulfonylurea, Type 2 diabetes | Diabetologia |
| Cardiovascular risk factors and major recurrent coronary events: A genetic liability study in patients with coronary artery disease in the UK Biobank. | Noordam R, Brochard TA, Drewes YM, Gussekloo J, Mooijaart SP, Willems van Dijk K, Trompet S, Jukema JW, van Heemst D | 2023-07-01 | LDL cholesterol, Mendelian randomization, coronary artery disease, recurrent disease | Atherosclerosis |
| “So let me give you money, you give me what I want”: decision-making priorities around contraceptive method and source choice among young women in Kenya. | Calhoun LM, Mandal M, Onyango B, Waga E, McGuire C, van den Akker T, Beňová L, Delvaux T, Zulu EM, Speizer IS | 2023-06-26 | Family planning, Method choice, Method source, Service delivery point, Youth | Reproductive health |
| Impact of anesthetist licensing examination on quality of education in Ethiopia: a qualitative study of faculty and student perceptions. | Asemu YM, Yigzaw T, Desta FA, Melese TA, Gemeda LA, Scheele F, van den Akker T | 2023-06-22 | Anesthesia, Assessment, Associate clinician anesthetists, Education Quality, National Licensing Examination, Non-physician anesthetists | BMC medical education |
| Current Pyuria Cutoffs Promote Inappropriate Urinary Tract Infection Diagnosis in Older Women. | Bilsen MP, Aantjes MJ, van Andel E, Stalenhoef JE, van Nieuwkoop C, Leyten EMS, Delfos NM, Sijbom M, Numans ME, Achterberg WP, Mooijaart SP, van der Beek MT, Cobbaert CM, Conroy SP, Visser LG, Lambregts MMC | 2023-06-16 | asymptomatic bacteriuria, microscopy, pyuria, urinary tract infection, urine flowcytometry | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America |
| Out of sight, out of mind? Evidence from cross-sectional surveys on hidden caesarean sections among women with stillbirths in Ghana, 2007 and 2017. | Zethof S, Christou A, Benova L, Beyuo TK, van Roosmalen J, van den Akker T | 2023-06-01 | cross-sectional survey, indices of health and disease and standardisation of rates, maternal health, obstetrics, surgery | BMJ global health |
| Biomarkers of the ageing immune system and their association with frailty – A systematic review. | Tran Van Hoi E, De Glas NA, Portielje JEA, Van Heemst D, Van Den Bos F, Jochems SP, Mooijaart SP | 2023-06-01 | Ageing, Biomarkers, Elderly, Frailty, Immunosenescence, Inflammaging | Experimental gerontology |
| Correction to: palliative care in advanced Huntington’s disease: a scoping review. | Boersema-Wijma DJ, van Duijn E, Heemskerk AW, van der Steen JT, Achterberg WP | 2023-05-31 | BMC palliative care | |
| Temporal changes in characteristics and external validity of randomized controlled trials in older people from 2012 to 2019. | van Eijk E, van der Spek YM, van Deudekom FJA, van den Bos F, Mooijaart SP, Trompet S | 2023-05-24 | Geriatric assessments, Older individuals, Randomized controlled trials, Systematic review, Temporal changes | BMC geriatrics |
| Frequencies and reasons for unplanned emergency department return visits by older adults: a cohort study. | van Loon-van Gaalen M, Voshol IE, van der Linden MC, Gussekloo J, van der Mast RC | 2023-05-18 | Emergency department, Geriatric, Older patients, Return presentations, Unplanned return | BMC geriatrics |
| Time trends in treatment patterns and survival of older patients with synchronous metastatic colorectal cancer in the Netherlands: A population-based study. | Baltussen JC, de Glas NA, Liefers GJ, Slingerland M, Speetjens FM, van den Bos F, Cloos-van Balen M, Verschoor AJ, Jochems A, Spierings LEAMM, Holterhues C, van Gerven LA, Mooijaart SP, Portielje JEA, Derks MGM | 2023-05-15 | metastatic colorectal cancer, older adults, population-based study, survival, treatment patterns | International journal of cancer |
| Uncovering the Relationship between Selenium Status, Age, Health, and Dietary Habits: Insights from a Large Population Study including Nonagenarian Offspring from the MARK-AGE Project. | Giacconi R, Piacenza F, Aversano V, Zampieri M, Bürkle A, Villanueva MM, Dollé MET, Jansen E, Grune T, Gonos ES, Franceschi C, Capri M, Weinberger B, Sikora E, Toussaint O, Debacq-Chainiaux F, Stuetz W, Slagboom PE, Bernhardt J, Fernández-Sánchez ML, Provinciali M, Malavolta M | 2023-05-04 | aging, inflammation, longevity, plasma selenium, selenium fractionation | Nutrients |
| Prevalence and risk factors of burden among caregivers of older emergency department patients. | Zaalberg T, Barten DG, van Heugten CM, Klijnsma P, Knarren L, Hiemstra Y, Kurvers RAJ, Lekx AW, Mooijaart SP, Janssen-Heijnen M | 2023-05-04 | Scientific reports | |
| Palliative care in advanced Huntington’s disease: a scoping review. | Boersema-Wijma DJ, van Duijn E, Heemskerk AW, van der Steen JT, Achterberg WP | 2023-05-03 | Advance Care Planning, Hospice Care, Huntington’s Disease, Neurodegenerative diseases, Palliative Care, Terminal Care | BMC palliative care |
| Low leukocyte mitochondrial DNA abundance drives atherosclerotic cardiovascular diseases: a cohort and Mendelian randomization study. | Luo J, Noordam R, Jukema JW, van Dijk KW, Hägg S, Grassmann F, le Cessie S, van Heemst D | 2023-05-02 | Coronary artery disease, Heart failure, Mendelian randomization, Mitochondrial DNA | Cardiovascular research |
| Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus. | Mathieson I, Day FR, Barban N, Tropf FC, Brazel DM, Vaez A, van Zuydam N, Bitarello BD, Gardner EJ, Akimova ET, Azad A, Bergmann S, Bielak LF, Boomsma DI, Bosak K, Brumat M, Buring JE, Cesarini D, Chasman DI, Chavarro JE, Cocca M, Concas MP, Davey Smith G, Davies G, Deary IJ, Esko T, Faul JD, Franco O, Ganna A, Gaskins AJ, Gelemanovic A, de Geus EJC, Gieger C, Girotto G, Gopinath B, Grabe HJ, Gunderson EP, Hayward C, He C, van Heemst D, Hill WD, Hoffmann ER, Homuth G, Hottenga JJ, Huang H, Hyppӧnen E, Ikram MA, Jansen R, Johannesson M, Kamali Z, Kardia SLR, Kavousi M, Kifley A, Kiiskinen T, Kraft P, Kühnel B, Langenberg C, Liew G, Lind PA, Luan J, Mägi R, Magnusson PKE, Mahajan A, Martin NG, Mbarek H, McCarthy MI, McMahon G, Medland SE, Meitinger T, Metspalu A, Mihailov E, Milani L, Missmer SA, Mitchell P, Møllegaard S, Mook-Kanamori DO, Morgan A, van der Most PJ, de Mutsert R, Nauck M, Nolte IM, Noordam R, Penninx BWJH, Peters A, Peyser PA, Polašek O, Power C, Pribisalic A, Redmond P, Rich-Edwards JW, Ridker PM, Rietveld CA, Ring SM, Rose LM, Rueedi R, Shukla V, Smith JA, Stankovic S, Stefánsson K, Stöckl D, Strauch K, Swertz MA, Teumer A, Thorleifsson G, Thorsteinsdottir U, Thurik AR, Timpson NJ, Turman C, Uitterlinden AG, Waldenberger M, Wareham NJ, Weir DR, Willemsen G, Zhao JH, Zhao W, Zhao Y, Snieder H, den Hoed M, Ong KK, Mills MC, Perry JRB | 2023-05-01 | Nature human behaviour | |
| Effect of clinical chorioamnionitis on breathing effort in premature infants at birth: a retrospective case-control study. | Panneflek TJR, Kuypers KLAM, Polglase GR, Hooper SB, van den Akker T, Te Pas AB | 2023-05-01 | Allergy and Immunology, intensive care units, neonatal, neonatology, resuscitation | Archives of disease in childhood. Fetal and neonatal edition |
| Vacuum extraction or caesarean section in the second stage of labour: A systematic review. | Thierens S, van Binsbergen A, Nolens B, van den Akker T, Bloemenkamp K, Rijken MJ | 2023-05-01 | caesarean section, maternal, morbidity, mortality, neonatal, operative vaginal delivery, perinatal, vacuum extraction | BJOG : an international journal of obstetrics and gynaecology |
| Association between endocrine therapy and cognitive decline in older women with early breast cancer: Findings from the prospective CLIMB study. | Baltussen JC, Derks MGM, Lemij AA, de Glas NA, Fiocco M, Linthorst-Niers EMH, Vulink AJE, van Gerven L, Guicherit OR, van Dalen T, Merkus JWS, Lans TE, van der Pol CC, Mooijaart SP, Portielje JEA, Liefers GJ | 2023-05-01 | Breast cancer, Cognition, Endocrine therapy, Longitudinal, MMSE, Older women | European journal of cancer (Oxford, England : 1990) |
| Establishing the Ethiopian Obstetric Surveillance System for Monitoring Maternal Outcomes in Eastern Ethiopia: A Pilot Study. | Tura AK, Girma S, Dessie Y, Bekele D, Stekelenburg J, van den Akker T, Knight M | 2023-04-28 | Global health, science and practice | |
| Effects of discontinuation of levothyroxine treatment in older adults: protocol for a self-controlled trial. | Ravensberg AJ, Poortvliet RKE, Du Puy RS, Dekkers OM, Mooijaart SP, Gussekloo J | 2023-04-25 | Aged, GENERAL MEDICINE (see Internal Medicine), GERIATRIC MEDICINE, PRIMARY CARE, Quality of Life, Thyroid disease | BMJ open |
| Informal Caregiver Stroke Program in Geriatric Rehabilitation of Stroke Patients: A Qualitative Study. | Vielvoye M, Nanninga CS, Achterberg WP, Caljouw MAA | 2023-04-24 | caregiver burden, geriatric rehabilitation, informal caregiver, qualitative, stroke | Journal of clinical medicine |
| A study protocol of external validation of eight COVID-19 prognostic models for predicting mortality risk in older populations in a hospital, primary care, and nursing home setting. | Zahra A, Luijken K, Abbink EJ, van den Berg JM, Blom MT, Elders P, Festen J, Gussekloo J, Joling KJ, Melis R, Mooijaart S, Peters JB, Polinder-Bos HA, van Raaij BFM, Smorenberg A, la Roi-Teeuw HM, Moons KGM, van Smeden M | 2023-04-04 | COVID-19, COVID-19-related mortality, External validation, Older, Prognostic models | Diagnostic and prognostic research |
| Pooled analysis of epigenome-wide association studies of food consumption in KORA, TwinsUK and LLS. | Hellbach F, Sinke L, Costeira R, Baumeister SE, Beekman M, Louca P, Leeming ER, Mompeo O, Berry S, Wilson R, Wawro N, Freuer D, Hauner H, Peters A, Winkelmann J, Koenig W, Meisinger C, Waldenberger M, Heijmans BT, Slagboom PE, Bell JT, Linseisen J | 2023-04-01 | Diet, EWAS, Food group, High-fat foods, Humans | European journal of nutrition |
| Atypical presentation of COVID-19 in older patients is associated with frailty but not with adverse outcomes. | van Son JE, Kahn ECP, van der Bol JM, Barten DG, Blomaard LC, van Dam C, Ellerbroek J, Jansen SWM, Lekx A, van der Linden CMJ, Looman R, Maas HAAM, Mattace-Raso FUS, Mooijaart SP, van Munster BC, Peters A, Polinder-Bos HA, Smits RAL, Spies PE, Wassenburg A, Wassenburg N, Willems HC, Schouten HJ, Robben SHM | 2023-04-01 | Atypical presentation, COVID-19, Frailty, Older adults, SARS-CoV-2 | European geriatric medicine |
| The Perceived Impact of the Namaste Care Family Program on Nursing Home Residents with Dementia, Staff, and Family Caregivers: A Qualitative Study. | Smaling HJA, Francke AL, Achterberg WP, Joling KJ, van der Steen JT | 2023-04-01 | Namaste Care, challenging behavior, dementia, nursing home, person-centered care | Journal of palliative care |
| Geriatric rehabilitation care after hip fracture. | Mattiazzo GF, Drewes YM, van Eijk M, Achterberg WP | 2023-04-01 | Care pathways, Geriatric rehabilitation, Hip fractures, Standard care | European geriatric medicine |
| Proxy Decision-Making for Clinical Research in Nursing Home Residents with Dementia: A Qualitative Analysis. | Bogaerts JMK, Warmerdam LA, Achterberg WP, Gussekloo J, Poortvliet RKE | 2023-04-01 | Dementia, nursing home, proxy decision-making, qualitative study, randomized controlled trial, research | Journal of the American Medical Directors Association |
| Cortical iron accumulation in MAPT‐ and C9orf 72‐associated frontotemporal lobar degeneration | Giannini LAA, Bulk M, Kenkhuis B, Rajicic A, Melhem S, Hegeman‐Kleinn I, Bossoni L, Suidgeest E, Dopper EGP, van Swieten JC, van der Weerd L, Seelaar H | 2023-03-27 | Brain Pathology | |
| [Vitamin D supplementation for all older people with COVID-19?]. | Mooijaart SP, Dekkers OM, Van den Bos F | 2023-03-16 | Nederlands tijdschrift voor geneeskunde | |
| [Which blood pressure target for the frail older patient?]. | Claassen JAHR, Richard E, Mooijaart SP, Moll van Charante EP | 2023-03-15 | Nederlands tijdschrift voor geneeskunde | |
| Course of fear of falling after hip fracture: findings from a 12-month inception cohort. | Scheffers-Barnhoorn MN, Haaksma ML, Achterberg WP, Niggebrugge AH, van der Sijp MP, van Haastregt JC, van Eijk M | 2023-03-14 | GERIATRIC MEDICINE, Hip, REHABILITATION MEDICINE | BMJ open |
| Epigenome-Wide Association Study Reveals CpG Sites Associated with Thyroid Function and Regulatory Effects on KLF9. | Weihs A, Chaker L, Martin TC, Braun KVE, Campbell PJ, Cox SR, Fornage M, Gieger C, Grabe HJ, Grallert H, Harris SE, Kühnel B, Marioni RE, Martin NG, McCartney DL, McRae AF, Meisinger C, van Meurs JBJ, Nano J, Nauck M, Peters A, Prokisch H, Roden M, Selvin E, Beekman M, van Heemst D, Slagboom EP, Swenson BR, Tin A, Tsai PC, Uitterlinden A, Visser WE, Völzke H, Waldenberger M, Walsh JP, Köttgen A, Wilson SG, Peeters RP, Bell JT, Medici M, Teumer A | 2023-03-01 | DNA methylation, KLF9, Mendelian randomization, gene expression, thyroid function | Thyroid : official journal of the American Thyroid Association |
| (Un)warranted variation in local hospital protocols for neonatal referral to the pediatrician: An explorative study in the Netherlands. | Goodarzi B, Seijmonsbergen-Schermers A, Cronie D, van Laerhoven H, van den Akker T, van Kaam AH, de Jonge A | 2023-03-01 | neonatal care, neonatel referral, pediatric consultation, protocols, variation | Birth (Berkeley, Calif.) |
| “My baby is fine, no need for more clinic visits.” Facilitators and barriers for utilisation of follow-up services for children born preterm in low-resource setting: Parents’ perceptions. | Namiiro FB, Nolens B, Rujumba J, Kiguli S, Batte A, van den Akker T | 2023-03-01 | Uganda, barriers, facilitators, follow-up, preterm, qualitative study | Tropical medicine & international health : TM & IH |
| Frailty and treatment decisions in older patients with vulvar cancer: A single-center cohort study. | Gans EA, Portielje JEA, Dekkers OM, de Kroon CD, van Munster BC, Derks MGM, Trompet S, van Holstein Y, Mooijaart SP, van Poelgeest MIE, van den Bos F | 2023-03-01 | Frailty, Geriatric assessment, Geriatric oncology, Treatment de-escalation, Vulvar cancer | Journal of geriatric oncology |
| The impact of the mySupport advance care planning intervention on family caregivers’ perceptions of decision-making and care for nursing home residents with dementia: pretest-posttest study in six countries. | Bavelaar L, Visser M, Walshe C, Preston N, Kaasalainen S, Sussman T, Cornally N, Hartigan I, Loucka M, di Giulio P, Brazil K, Achterberg WP, van der Steen JT | 2023-03-01 | decision-making, dementia, family caregivers, nursing homes, older people | Age and ageing |
| Setting your clock: associations between timing of objective physical activity and cardiovascular disease risk in the general population. | Albalak G, Stijntjes M, van Bodegom D, Jukema JW, Atsma DE, van Heemst D, Noordam R | 2023-02-14 | Chronoactivity, Coronary artery disease, Patterns, Physical activity, Stroke | European journal of preventive cardiology |
| Collective Prevention of Non-Communicable Diseases in an Ageing Population with Community Care. | Kuppen R, de Leede M, Lindenberg J, van Bodegom D | 2023-02-10 | collective prevention, community care, lifestyle, public health promotion, social environment | International journal of environmental research and public health |
| A Qualitative Study Exploring Professional Perspectives of a Challenging Rehabilitation Environment for Geriatric Rehabilitation. | Tijsen LMJ, Derksen EWC, Achterberg WP, Buijck BI | 2023-02-03 | care process, challenging rehabilitation environment, geriatric rehabilitation, post-acute care | Journal of clinical medicine |
| Lipid-induced transcriptomic changes in blood link to lipid metabolism and allergic response. | Dekkers KF, Slieker RC, Ioan-Facsinay A, van Iterson M, Ikram MA, van Greevenbroek MMJ, Veldink JH, Franke L, Boomsma DI, Slagboom PE, Jukema JW, Heijmans BT | 2023-02-01 | Nature communications | |
| The association of measures of body shape and adiposity with incidence of cardiometabolic disease from an ageing perspective. | Meulmeester FL, Willems van Dijk K, Mooijaart SP, van Heemst D, Noordam R | 2023-02-01 | Adiposity, Body composition, Cardiometabolic diseases, Geroscience, UK Biobank | GeroScience |
| Post-mortem 7T MR imaging and neuropathology in middle stage juvenile-onset Huntington disease: A case report. | Bakels HS, van Duinen SG, de Bresser J, van Roon-Mom WMC, van der Weerd L, de Bot ST | 2023-02-01 | Huntington disease, Vonsattel grading system, juvenile-onset Huntington disease, magnetic resonance imaging, neuropathologic staging, neuropathology, post-mortem | Neuropathology and applied neurobiology |
| Clinical outcome in patients with suspected inflammatory neuropsychiatric lupus treated with immunosuppression: an observational cohort study. | Monahan RC, Beaart-van de Voorde LJJ, Fronczek R, de Bresser J, Eikenboom J, Kloppenburg M, Middelkoop HAM, Terwindt GM, van der Wee NJA, Huizinga TWJ, Steup-Beekman GM | 2023-02-01 | lupus erythematosus, systemic, outcome assessment, healthcare, treatment | Lupus science & medicine |
| Bacterial DNAemia in Older Participants and Nonagenarian Offspring and Association With Redox Biomarkers: Results From MARK-AGE Study. | Giacconi R, D'Aquila P, Malavolta M, Piacenza F, Bürkle A, Villanueva MM, Dollé MET, Jansen E, Grune T, Gonos ES, Franceschi C, Capri M, Gradinaru D, Grubeck-Loebenstein B, Sikora E, Stuetz W, Weber D, Toussaint O, Debacq-Chainiaux F, Hervonen A, Hurme M, Slagboom PE, Schön C, Bernhardt J, Breusing N, Duncan T, Passarino G, Bellizzi D, Provinciali M | 2023-01-26 | Aging, Blood bacterial DNA, Dysbiosis, Inflammation, Longevity | The journals of gerontology. Series A, Biological sciences and medical sciences |
| How to Conduct International Geriatric Rehabilitation Research? | Haaksma ML, Gordon AL, van Dam van Isselt EF, Schols JMGA, Everink IHJ, Cameron ID, Becker C, Grund S, Achterberg WP | 2023-01-26 | geriatric rehabilitation, methodology, study design | Journal of clinical medicine |
| Weight loss, visit-to-visit body weight variability and cognitive function in older individuals. | Zonneveld MH, Noordam R, Sabayan B, Stott DJ, Mooijaart SP, Blauw GJ, Jukema JW, Sattar N, Trompet S | 2023-01-08 | cognition, cognitive decline, cognitive function, dementia, older adults, older people, weight change, weight loss | Age and ageing |
| The effect of thyroid hormone therapy on muscle function, strength and mass in older adults with subclinical hypothyroidism-an ancillary study within two randomized placebo controlled trials. | Netzer S, Chocano-Bedoya P, Feller M, Janett-Pellegri C, Wildisen L, Büchi AE, Moutzouri E, Rodriguez EG, Collet TH, Poortvliet RKE, Mc Carthy VJC, Aeberli D, Aujesky D, Westendorp R, Quinn TJ, Gussekloo J, Kearney PM, Mooijaart S, Bauer DC, Rodondi N | 2023-01-08 | levothyroxine, muscle, older people, sarcopenia, subclinical hypothyroidism | Age and ageing |
| Association of Torquetenovirus Viremia with Physical Frailty and Cognitive Impairment in Three Independent European Cohorts. | Giacconi R, Laffon B, Costa S, Teixeira-Gomes A, Maggi F, Macera L, Spezia PG, Piacenza F, Bürkle A, Moreno-Villanueva M, Bonassi S, Valdiglesias V, Teixeira JP, Dollé MET, Rietman ML, Jansen E, Grune T, Gonos ES, Franceschi C, Capri M, Weinberger B, Sikora E, Stuetz W, Toussaint O, Debacq-Chainiaux F, Hervonen A, Hurme M, Slagboom PE, Schön C, Bernhardt J, Breusing N, Pásaro E, Maseda A, Lorenzo-López L, Millán-Calenti JC, Provinciali M, Malavolta M | 2023-01-01 | Aging, Cognitive impairment, Inflammation, Physical frailty, Torquetenovirus | Gerontology |
| Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci. | de Las Fuentes L, Schwander KL, Brown MR, Bentley AR, Winkler TW, Sung YJ, Munroe PB, Miller CL, Aschard H, Aslibekyan S, Bartz TM, Bielak LF, Chai JF, Cheng CY, Dorajoo R, Feitosa MF, Guo X, Hartwig FP, Horimoto A, Kolčić I, Lim E, Liu Y, Manning AK, Marten J, Musani SK, Noordam R, Padmanabhan S, Rankinen T, Richard MA, Ridker PM, Smith AV, Vojinovic D, Zonderman AB, Alver M, Boissel M, Christensen K, Freedman BI, Gao C, Giulianini F, Harris SE, He M, Hsu FC, Kühnel B, Laguzzi F, Li X, Lyytikäinen LP, Nolte IM, Poveda A, Rauramaa R, Riaz M, Robino A, Sofer T, Takeuchi F, Tayo BO, van der Most PJ, Verweij N, Ware EB, Weiss S, Wen W, Yanek LR, Zhan Y, Amin N, Arking DE, Ballantyne C, Boerwinkle E, Brody JA, Broeckel U, Campbell A, Canouil M, Chai X, Chen YI, Chen X, Chitrala KN, Concas MP, de Faire U, de Mutsert R, de Silva HJ, de Vries PS, Do A, Faul JD, Fisher V, Floyd JS, Forrester T, Friedlander Y, Girotto G, Gu CC, Hallmans G, Heikkinen S, Heng CK, Homuth G, Hunt S, Ikram MA, Jacobs DR, Kavousi M, Khor CC, Kilpeläinen TO, Koh WP, Komulainen P, Langefeld CD, Liang J, Liu K, Liu J, Lohman K, Mägi R, Manichaikul AW, McKenzie CA, Meitinger T, Milaneschi Y, Nauck M, Nelson CP, O'Connell JR, Palmer ND, Pereira AC, Perls T, Peters A, Polašek O, Raitakari OT, Rice K, Rice TK, Rich SS, Sabanayagam C, Schreiner PJ, Shu XO, Sidney S, Sims M, Smith JA, Starr JM, Strauch K, Tai ES, Taylor KD, Tsai MY, Uitterlinden AG, van Heemst D, Waldenberger M, Wang YX, Wei WB, Wilson G, Xuan D, Yao J, Yu C, Yuan JM, Zhao W, Becker DM, Bonnefond A, Bowden DW, Cooper RS, Deary IJ, Divers J, Esko T, Franks PW, Froguel P, Gieger C, Jonas JB, Kato N, Lakka TA, Leander K, Lehtimäki T, Magnusson PKE, North KE, Ntalla I, Penninx B, Samani NJ, Snieder H, Spedicati B, van der Harst P, Völzke H, Wagenknecht LE, Weir DR, Wojczynski MK, Wu T, Zheng W, Zhu X, Bouchard C, Chasman DI, Evans MK, Fox ER, Gudnason V, Hayward C, Horta BL, Kardia SLR, Krieger JE, Mook-Kanamori DO, Peyser PA, Province MM, Psaty BM, Rudan I, Sim X, Smith BH, van Dam RM, van Duijn CM, Wong TY, Arnett DK, Rao DC, Gauderman J, Liu CT, Morrison AC, Rotter JI, Fornage M | 2023-01-01 | cholesterol, educational attainment, genome-wide association study, lipids, meta-analysis, triglycerides | Frontiers in genetics |
| Maternal and perinatal death surveillance and response: a systematic review of qualitative studies. | Willcox ML, Okello IA, Maidwell-Smith A, Tura AK, van den Akker T, Knight M | 2023-01-01 | Bulletin of the World Health Organization | |
| Incidence, Indications, Risk Factors, and Outcomes of Emergency Peripartum Hysterectomy Worldwide: A Systematic Review and Meta-analysis. | Kallianidis AF, Rijntjes D, Brobbel C, Dekkers OM, Bloemenkamp KWM, van den Akker T | 2023-01-01 | Obstetrics and gynecology | |
| Primary Effusion Lymphoma in an HIV-Negative Patient with Chronic Myeloid Leukemia Treated with Dasatinib. | SahBandar IN, Sy CB, van den Akker T, Kim D, Geyer JT, Chadburn A, Cesarman E, Inghirami G, Allan JN, Siddiqui MT, Ouseph MM | 2023-01-01 | Chronic myeloid leukemia, Dasatinib, Lymphoma, Primary effusion lymphoma | Pathobiology : journal of immunopathology, molecular and cellular biology |
| Receiving antenatal care components and associated factors in Northwestern Tanzania. | Massenga J, Jeremiah K, Kitinya W, Kim YM, van Roosmalen J, van den Akker T | 2023-01-01 | PloS one | |
| Correction: No increase in use of hospitals for childbirth in Tanzania over 25 years: Accumulation of inequity among poor, rural, high parity women. | Straneo M, Beňová L, van den Akker T, Pembe AB, Smekens T, Hanson C | 2023-01-01 | PLOS global public health | |
| The more, the better: influence of family planning discussions during the maternal, newborn and child health continuum of care on postpartum contraceptive uptake and method type among young women in Ethiopia. | Calhoun LM, Winston J, Beňová L, Speizer IS, Delvaux T, Shiferaw S, Seme A, Karp C, Zimmerman L, van den Akker T | 2023-01-01 | adolescent, continuum of care, contraception, counseling, family planning, integration, postpartum, prenatal care, youth | Gates open research |
| The Ethiopian Anesthetist Licensing Examination and Associated Improvement in in-School Student Performance: A Retrospective Study. | Asemu YM, Yigzaw T, Ayalew F, Akalu L, Scheele F, van den Akker T | 2023-01-01 | anesthesia, anesthetist, associate clinician, licensing examination, non-physician | Advances in medical education and practice |
| Ethiopian Anesthetist Licensing Examination: A Qualitative Study of Concerns and Unintended Consequences. | Asemu YM, Yigzaw T, Ayalew F, Akalu L, Scheele F, van den Akker T | 2023-01-01 | anesthesia, anesthetist, associate clinician, licensing examination, non-physician | Advances in medical education and practice |
| Association of low blood pressure and falls: An analysis of data from the Leiden 85-plus Study. | Röthlisberger D, Jungo KT, Bütikofer L, Poortvliet RKE, Gussekloo J, Streit S | 2023-01-01 | PloS one | |
| Carotid Artery Stenosis and Progression of Hemispheric Brain Atrophy: The SMART-MR Study. | Ghaznawi R, Rissanen I, de Bresser J, Kuijf HJ, Zuithoff NPA, Hendrikse J, Geerlings MI | 2023-01-01 | Brain atrophy, Carotid artery stenosis, Cohort studies, MRI | Cerebrovascular diseases (Basel, Switzerland) |
| Postoperative delirium is associated with grey matter brain volume loss. | Kant IMJ, de Bresser J, van Montfort SJT, Witkamp TD, Walraad B, Spies CD, Hendrikse J, van Dellen E, Slooter AJC | 2023-01-01 | brain infarcts, brain volume, delirium, encephalopathy, grey matter | Brain communications |
| The prevalence and severity of fatigue in meningioma patients and its association with patient-, tumor- and treatment-related factors. | Quach KT, Dirven L, Vingerhoed AM, de Bresser J, Dammers R, Bos EM, Moojen WA, Peul WC, Taphoorn MJB, Zamanipoor Najafabadi AH, van Furth WR | 2023-01-01 | central nervous system tumor, fatigue, long-term, meningioma, patient-reported outcome | Neuro-oncology advances |
| Study protocol of IMAGINE-HD: Imaging iron accumulation and neuroinflammation with 7T-MRI + CSF in Huntington’s disease. | van de Zande NA, Bulk M, Najac C, van der Weerd L, de Bresser J, Lewerenz J, Ronen I, de Bot ST | 2023-01-01 | Biomarkers, CSF, Huntington’s disease, Iron accumulation, MRI, Neuroinflammation | NeuroImage. Clinical |
| White matter changes measured by multi-component MR Fingerprinting in multiple sclerosis. | Nagtegaal MA, Hermann I, Weingärtner S, Martinez-Heras E, Solana E, Llufriu S, Gass A, Poot DHJ, van Osch MJP, Vos FM, de Bresser J | 2023-01-01 | MR Fingerprinting, Multi-component analysis, Multiple Sclerosis, Quantitative MRI, White matter damage | NeuroImage. Clinical |
| MRI phenotypes of glioblastomas early after treatment are suggestive of overall patient survival. | Schmitz-Abecassis B, Dirven L, Jiang J, Keller JA, Croese RJI, van Dorth D, Ghaznawi R, Kant IMJ, Taphoorn MJB, van Osch MJP, Koekkoek JAF, de Bresser J | 2023-01-01 | MRI, glioblastoma, perfusion, tumor progression | Neuro-oncology advances |
| A Qualitative Study Exploring Rehabilitant and Informal Caregiver Perspectives of a Challenging Rehabilitation Environment for Geriatric Rehabilitation. | Tijsen LMJ, Derksen EWC, Achterberg WP, Buijck BI | 2023-01-01 | challenging rehabilitation environment, geriatric rehabilitation, informal caregiver, rehabilitant | Journal of patient experience |
| Supporting Resilience of Older Adults with Cognitive Decline Requires a Multi-Level System Approach. | Peeters G, Kok A, de Bruin SR, van Campen C, Graff M, Nieuwboer M, Huisman M, van Munster B, van der Zee EA, Kas MJ, Perry M, Gerritsen DL, Vreede-Chabot E, The AM, van Hout H, Bakker FC, Achterberg WP, van der Steen JT, Smits C, Melis R, Olde Rikkert M | 2023-01-01 | Cognition, Dementia, Old age, Resilience, Socio-ecological system | Gerontology |
| The effect of garden use on quality of life and behavioral and psychological symptoms of dementia in people living with dementia in nursing homes: a systematic review. | van der Velde-van Buuringen M, Hendriks-van der Sar R, Verbeek H, Achterberg WP, Caljouw MAA | 2023-01-01 | behavioral and psychological symptoms of dementia, dementia, garden use, nursing homes, quality of life, systematic review | Frontiers in psychiatry |
| Scaling up Locally Adapted Clinical Practice Guidelines for Improving Childbirth Care in Tanzania: A Protocol for Programme Theory and Qualitative Methods of the PartoMa Scale-up Study. | Sørensen JB, Housseine N, Maaløe N, Bygbjerg IC, Pinkowski Tersbøl B, Konradsen F, Sequeira Dmello B, van Den Akker T, van Roosmalen J, Mookherji S, Siaity E, Osaki H, Khamis RS, Kujabi ML, John TW, Wolf Meyrowitsch D, Mbekenga C, Skovdal M, L Kidanto H | 2022-12-31 | Practice theory, co-creation, intervention, obstetrics, respectful maternity care | Global health action |
| Scaling up context-tailored clinical guidelines and training to improve childbirth care in urban, low-resource maternity units in Tanzania: A protocol for a stepped-wedged cluster randomized trial with embedded qualitative and economic analyses (The PartoMa Scale-Up Study). | Maaløe N, Housseine N, Sørensen JB, Obel J, Sequeira DMello B, Kujabi ML, Osaki H, John TW, Khamis RS, Muniro ZSS, Nkungu DJ, Pinkowski Tersbøl B, Konradsen F, Mookherji S, Mbekenga C, Meguid T, van Roosmalen J, Bygbjerg IC, van den Akker T, Jensen AK, Skovdal M, L Kidanto H, Wolf Meyrowitsch D | 2022-12-31 | Africa, Obstetrics, co-creation, cost-effectiveness, de-colonizing, intervention, low dose high frequency training, perinatal death, programme theory, respectful maternity care, stillbirth, urbanization | Global health action |
| Strategies to Increase Willingness to Receive a COVID-19 Vaccine among Nursing Home Staff. | van Tol LS, Meester W, Caljouw MAA, Achterberg WP | 2022-12-31 | COVID-19, nursing homes, staff, vaccination | Infectious disease reports |
| Clustered Mendelian randomization analyses identify distinct and opposing pathways in the association between genetically influenced insulin-like growth factor-1 and type 2 diabetes mellitus. | Wang W, Tesfay EB, van Klinken JB, Willems van Dijk K, Bartke A, van Heemst D, Noordam R | 2022-12-13 | Clustered Mendelian randomization analysis, Mendelian randomization analysis, cohort studies, insulin-like growth factor-1, type 2 diabetes | International journal of epidemiology |
| Tract-based white matter hyperintensity patterns in patients with systemic lupus erythematosus using an unsupervised machine learning approach. | Rumetshofer T, Inglese F, de Bresser J, Mannfolk P, Strandberg O, Jönsen A, Bengtsson A, Nilsson M, Knutsson L, Lätt J, Steup-Beekman GM, Huizinga TWJ, van Buchem MA, Ronen I, Sundgren PC | 2022-12-09 | Scientific reports | |
| Should we take Mum to market? Quality and funding in the care home sector. | Allan S, Irvine L, Achterberg WP | 2022-12-05 | care home, older people, ownership, quality of care | Age and ageing |
| Agreement between nicotine metabolites in blood and self-reported smoking status: The Netherlands Epidemiology of Obesity study. | Folpmers S, Mook-Kanamori DO, de Mutsert R, Rosendaal FR, Willems van Dijk K, van Heemst D, Noordam R, le Cessie S | 2022-12-01 | Agreement, Nicotine metabolites, Self reported smoking status, Smoking | Addictive behaviors reports |
| Thyroid antibodies and levothyroxine effects in subclinical hypothyroidism: A pooled analysis of two randomized controlled trials. | Lyko C, Blum MR, Abolhassani N, Stuber MJ, Del Giovane C, Feller M, Moutzouri E, Oberle J, Jungo KT, Collet TH, den Elzen WPJ, Poortvliet RKE, Du Puy RS, Dekkers OM, Trompet S, Jukema JW, Aujesky D, Quinn T, Westendorp R, Kearney PM, Gussekloo J, Van Heemst D, Mooijaart SP, Bauer DC, Rodondi N | 2022-12-01 | autoimmune thyroid disease, levothyroxine treatment, subclinical hypothyroidism | Journal of internal medicine |
| Vascular disease and apathy symptoms in the very old: A cross-sectional and longitudinal meta-analysis of individual participant data. | van der Klei VMGTH, Poortvliet RKE, Bogaerts JMK, Blom JW, Mooijaart SP, Teh R, Muru-Lanning M, Palapar L, Kingston A, Robinson L, Kerse N, Gussekloo J | 2022-12-01 | atherosclerosis, meta-analysis, older people, prospective, vascular apathy | International journal of geriatric psychiatry |
| White matter hyperintensity shape is associated with cognitive functioning – the SMART-MR study. | Zwartbol MHT, Ghaznawi R, Jaarsma-Coes M, Kuijf H, Hendrikse J, de Bresser J, Geerlings MI | 2022-12-01 | Aging, Cognitive functioning, MRI, SMART-MR study, Shape analysis, White matter hyperintensities | Neurobiology of aging |
| Systematic review of measurement properties of the Canadian Occupational Performance Measure in geriatric rehabilitation. | de Waal MWM, Haaksma ML, Doornebosch AJ, Meijs R, Achterberg WP | 2022-12-01 | Aged, COPM, Geriatric rehabilitation, Reliability, Responsiveness, Validity | European geriatric medicine |
| Post-acute COVID-19 geriatric rehabilitation : A European perspective. | van Dam van Isselt EF, Schols JMGA, Gordon AL, Achterberg WP, van Haastregt J, Becker C, Grund S, Bauer JM | 2022-12-01 | Coronavirus disease 2019, Older patients, Preparedness, Rehabilitation paradox, Review | Zeitschrift fur Gerontologie und Geriatrie |
| Antioxidant Supplementation in Oxidative Stress-Related Diseases: What Have We Learned from Studies on Alpha-Tocopherol? | Meulmeester FL, Luo J, Martens LG, Mills K, van Heemst D, Noordam R | 2022-11-24 | antioxidant supplementation, oxidative stress, reactive oxygen species, α-tocopherol | Antioxidants (Basel, Switzerland) |
| [Pain and neurocognitive disorders: current state of the art and remaining challenges]. | Achterberg WP, de Waal MWM, Cheuk-A-Lam-Balrak JMJJ, Crutzen-Braaksma P, van Dalen-Kok A, van Dam P, de Knegt NC, van Kooten J, Lobbezoo F, Smaling HJA, Sprenger GP, van der Steen JT, de Vries CNJ, Zwakhalen SMG, Smalbrugge M, Oosterman JM | 2022-11-24 | Assessment, Cognitive impairment, Dementia, Pain, Treatment | Tijdschrift voor gerontologie en geriatrie |
| Evaluating the feasibility, experiences, facilitators of and barriers to carers and volunteers delivering Namaste Care to people with dementia in their own home: a qualitative interview study in the UK and the Netherlands. | Haaksma ML, O'Driscoll C, Joling KJ, Achterberg WP, Francke AL, van der Steen JT, Smaling HJA | 2022-11-14 | Namaste Care, carers, community-dwelling, dementia, multisensory | BMJ open |
| Factors associated with formal and informal resource utilization in nursing home patients with and without dementia: cross-sectional analyses from the COSMOS trial. | Vislapuu M, Berge LI, Angeles RC, Kjerstad E, Mannseth J, Achterberg WP, Husebo BS | 2022-11-02 | Dementia, Formal care, Informal care, Nursing home | BMC health services research |
| Self-perceived functioning and (instrumental) activities of daily living questionnaires after a hip fracture: Do they tell the same story? | Ravensbergen WM, Timmer IL, Gussekloo J, Blom JW, van Eijk M, Achterberg WP, Evers AWM, van Dijk S, Drewes YM | 2022-11-02 | (instrumental) activities of daily living, hip fracture, older people, qualitative research, self-perceived functioning | Age and ageing |
| A longitudinal analysis of nosocomial bloodstream infections among preterm neonates. | Jansen SJ, van der Hoeven A, van den Akker T, Veenhof M, von Asmuth EGJ, Veldkamp KE, Rijken M, van der Beek M, Bekker V, Lopriore E | 2022-11-01 | Central-lines, Epidemiology, Hospital-acquired infections, Neonates | European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology |
| Labor augmentation with oxytocin in low- and lower-middle-income countries: a systematic review and meta-analysis. | Kujabi ML, Mikkelsen E, Housseine N, Obel J, D'Mello BS, Meyrowitsch DW, Hussein K, Schroll JB, Konradsen F, van Roosmalen J, van den Akker T, Maaløe N | 2022-11-01 | Apgar score, birth asphyxia, childbirth, clinical guidelines, low- and lower-middle-income countries, low-resource setting, neonatal encephalopathy, neonatal mortality, neonatal resuscitation, oxytocin augmentation, partograph, perinatal mortality, prolonged labor, stillbirths | AJOG global reports |
| Metabolomic profiles predict individual multidisease outcomes. | Buergel T, Steinfeldt J, Ruyoga G, Pietzner M, Bizzarri D, Vojinovic D, Upmeier Zu Belzen J, Loock L, Kittner P, Christmann L, Hollmann N, Strangalies H, Braunger JM, Wild B, Chiesa ST, Spranger J, Klostermann F, van den Akker EB, Trompet S, Mooijaart SP, Sattar N, Jukema JW, Lavrijssen B, Kavousi M, Ghanbari M, Ikram MA, Slagboom E, Kivimaki M, Langenberg C, Deanfield J, Eils R, Landmesser U | 2022-11-01 | Nature medicine | |
| PLIS: A metabolomic response monitor to a lifestyle intervention study in older adults. | Bogaards FA, Gehrmann T, Beekman M, van den Akker EB, van de Rest O, Hangelbroek RWJ, Noordam R, Mooijaart SP, de Groot LCPGM, Reinders MJT, Slagboom PE | 2022-11-01 | bioinformatics, healthy ageing, lifestyle intervention, machine learning, metabolomics, response monitor | FASEB journal : official publication of the Federation of American Societies for Experimental Biology |
| Subclinical thyroid dysfunction and incident diabetes: a systematic review and an individual participant data analysis of prospective cohort studies. | Alwan H, Villoz F, Feller M, Dullaart RPF, Bakker SJL, Peeters RP, Kavousi M, Bauer DC, Cappola AR, Yeap BB, Walsh JP, Brown SJ, Ceresini G, Ferrucci L, Gussekloo J, Trompet S, Iacoviello M, Moon JH, Razvi S, Bensenor IM, Azizi F, Amouzegar A, Valdés S, Colomo N, Wareham NJ, Jukema JW, Westendorp RGJ, Kim KW, Rodondi N, Del Giovane C | 2022-11-01 | European journal of endocrinology | |
| Accuracy and repeatability of joint sparsity multi-component estimation in MR Fingerprinting. | Nunez-Gonzalez L, Nagtegaal MA, Poot DHJ, de Bresser J, van Osch MJP, Hernandez-Tamames JA, Vos FM | 2022-11-01 | Accuracy, Brain, Multi-component MR Fingerprinting, Quantitative MRI, Repeatability, Segmentation | NeuroImage |
| Intraoperative electrocorticography using high-frequency oscillations or spikes to tailor epilepsy surgery in the Netherlands (the HFO trial): a randomised, single-blind, adaptive non-inferiority trial. | Zweiphenning W, Klooster MAV', van Klink NEC, Leijten FSS, Ferrier CH, Gebbink T, Huiskamp G, van Zandvoort MJE, van Schooneveld MMJ, Bourez M, Goemans S, Straumann S, van Rijen PC, Gosselaar PH, van Eijsden P, Otte WM, van Diessen E, Braun KPJ, Zijlmans M | 2022-11-01 | The Lancet. Neurology | |
| Time Trends in Treatment Strategies and Survival of Older versus Younger Patients with Synchronous Metastasised Melanoma-A Population-Based Study in the Netherlands Cancer Registry. | van der Ziel D, Derks MGM, Kapiteijn E, Bastiaannet E, Louwman M, van den Bos F, Mooijaart SP, Portielje JEA, de Glas NA | 2022-10-07 | geriatric oncology, immunotherapy, melanoma, older adults, survival | Cancers |
| Common Genetic Variation and Age of Onset of Anorexia Nervosa. | Watson HJ, Thornton LM, Yilmaz Z, Baker JH, Coleman JRI, Adan RAH, Alfredsson L, Andreassen OA, Ask H, Berrettini WH, Boehnke M, Boehm I, Boni C, Buehren K, Bulant J, Burghardt R, Chang X, Cichon S, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, de Zwaan M, Dedoussis G, DeSocio JE, Dick DM, Dikeos D, Dina C, Djurovic S, Dmitrzak-Weglarz M, Docampo-Martinez E, Duriez P, Egberts K, Ehrlich S, Eriksson JG, Escaramís G, Esko T, Estivill X, Farmer A, Fernández-Aranda F, Fichter MM, Föcker M, Foretova L, Forstner AJ, Frei O, Gallinger S, Giegling I, Giuranna J, Gonidakis F, Gorwood P, Gratacòs M, Guillaume S, Guo Y, Hakonarson H, Hauser J, Havdahl A, Hebebrand J, Helder SG, Herms S, Herpertz-Dahlmann B, Herzog W, Hinney A, Hübel C, Hudson JI, Imgart H, Jamain S, Janout V, Jiménez-Murcia S, Jones IR, Julià A, Kalsi G, Kaminská D, Kaprio J, Karhunen L, Kas MJH, Keel PK, Kennedy JL, Keski-Rahkonen A, Kiezebrink K, Klareskog L, Klump KL, Knudsen GPS, La Via MC, Le Hellard S, Leboyer M, Li D, Lilenfeld L, Lin B, Lissowska J, Luykx J, Magistretti P, Maj M, Marsal S, Marshall CR, Mattingsdal M, Meulenbelt I, Micali N, Mitchell KS, Monteleone AM, Monteleone P, Myers R, Navratilova M, Ntalla I, O'Toole JK, Ophoff RA, Padyukov L, Pantel J, Papežová H, Pinto D, Raevuori A, Ramoz N, Reichborn-Kjennerud T, Ricca V, Ripatti S, Ripke S, Ritschel F, Roberts M, Rotondo A, Rujescu D, Rybakowski F, Scherag A, Scherer SW, Schmidt U, Scott LJ, Seitz J, Silén Y, Šlachtová L, Slagboom PE, Slof-Op 't Landt MCT, Slopien A, Sorbi S, Świątkowska B, Tortorella A, Tozzi F, Treasure J, Tsitsika A, Tyszkiewicz-Nwafor M, Tziouvas K, van Elburg AA, van Furth EF, Walton E, Widen E, Zerwas S, Zipfel S, Bergen AW, Boden JM, Brandt H, Crawford S, Halmi KA, Horwood LJ, Johnson C, Kaplan AS, Kaye WH, Mitchell JE, Olsen CM, Pearson JF, Pedersen NL, Strober M, Werge T, Whiteman DC, Woodside DB, Gordon S, Maguire S, Larsen JT, Parker R, Petersen LV, Jordan J, Kennedy M, Wade TD, Birgegård A, Lichtenstein P, Landén M, Martin NG, Mortensen PB, Breen G, Bulik CM | 2022-10-01 | Age of onset, Anorexia nervosa, Early-onset, GWAS, Genetic risk score, Genetics, Menarche, Mendelian randomization, Puberty | Biological psychiatry global open science |
| Assessment of the bi-directional relationship between blood mitochondrial DNA copy number and type 2 diabetes mellitus: a multivariable-adjusted regression and Mendelian randomisation study. | Wang W, Luo J, Willems van Dijk K, Hägg S, Grassmann F, T Hart LM, van Heemst D, Noordam R | 2022-10-01 | Mendelian randomisation, Mitochondrial DNA copy number, Prospective analyses, Type 2 diabetes mellitus | Diabetologia |
| Predictors of HIV Among 1 Million Clients in High-Risk Male Populations in Tanzania. | Mbita G, Komba AN, Casalini C, Bazant E, Curran K, Christensen A, Nyato D, Kim YM, Reed J, Makyao N, Kategile U, Conserve DF, Faini D, van Roosmalen J, van den Akker T | 2022-10-01 | Male client of female sex workers, Men living in areas with high risk of HIV, Men who have sex with men, Sexually transmitted infections, Tanzania | AIDS and behavior |
| Physiological-based cord clamping in very preterm infants: the Aeration, Breathing, Clamping 3 (ABC3) trial-study protocol for a multicentre randomised controlled trial. | Knol R, Brouwer E, van den Akker T, DeKoninck PLJ, Lopriore E, Onland W, Vermeulen MJ, van den Akker-van Marle ME, van Bodegom-Vos L, de Boode WP, van Kaam AH, Reiss IKM, Polglase GR, Hutten GJ, Prins SA, Mulder EEM, Hulzebos CV, van Sambeeck SJ, van der Putten ME, Zonnenberg IA, Hooper SB, Te Pas AB | 2022-10-01 | Cord clamping, Physiological-based cord clamping, Preterm infants, Randomised clinical trial, Study protocol | Trials |
| Delirium in older COVID-19 patients: Evaluating risk factors and outcomes. | Kroon B, Beishuizen SJE, van Rensen IHT, Barten DG, Mehagnoul-Schipper JJ, van der Bol JM, Ellerbroek JLJ, Festen J, van de Glind EMM, Hempenius L, van der Jagt M, Jansen SWM, van der Linden CJM, Mooijaart SP, van Munster BC, Oosterwijk LLE, Smit L, Urlings-Strop LC, Willems HC, Mattace-Raso FUS, Polinder-Bos HA | 2022-10-01 | CFS, COVID‐19, delirium, mortality | International journal of geriatric psychiatry |
| Change in Advance Care Plans of Nursing Home Residents With Dementia and Pneumonia: Secondary Analysis of Randomized Controlled Trial Data. | Bavelaar L, Visser M, Schlicksupp P, Tilburgs B, van der Maaden T, Achterberg WP, van der Steen JT | 2022-10-01 | Advance care planning, dementia, nursing homes, pneumonia, shared decision making | Journal of the American Medical Directors Association |
| Lessons learned from the perinatal audit of uterine rupture in the Netherlands: A mixed-method study. | Rosman AN, van Dillen J, Zwart J, Overtoom E, Schaap T, Bloemenkamp K, van den Akker T | 2022-09-01 | audit, maternal near miss, perinatal mortality, severe maternal morbidity, trial of labor after cesarean section, uterine rupture | Health science reports |
| Experiences of a dedicated Heart and Maternal Health Service providing multidisciplinary care to pregnant women with cardiac disease in a tertiary centre in Namibia. | Heemelaar S, Agapitus N, van den Akker T, Stekelenburg J, Mackenzie S, Hugo-Hamman C, Auala T | 2022-09-01 | Namibia, cardiac disease in pregnancy, cardiomyopathy, maternal mortality, pregnancy complications, rheumatic heart disease, sub-Saharan Africa | Tropical medicine & international health : TM & IH |
| Multimodal tract-based MRI metrics outperform whole brain markers in determining cognitive impact of small vessel disease-related brain injury. | De Luca A, Kuijf H, Exalto L, Thiebaut de Schotten M, Biessels GJ | 2022-09-01 | Cerebral small vessel disease, Cognition, Diffusion MRI, Fiber tractography, Neural network | Brain structure & function |
| Disentangling the varying associations between systolic blood pressure and health outcomes in the very old: an individual patient data meta-analysis. | Bogaerts JMK, Poortvliet RKE, van der Klei VMGTH, Achterberg WP, Blom JW, Teh R, Muru-Lanning M, Kerse N, Rolleston A, Jagger C, Kingston A, Robinson L, Arai Y, Shikimoto R, Gussekloo J | 2022-09-01 | Journal of hypertension | |
| Every maternal near-miss counts: Need for a national audit in South Africa? A mixed-methods study. | Heitkamp A, Suh J, Gebhardt S, Van Roosmalen J, Murray LR, De Vries JI, Van den Akker T, Theron G | 2022-08-30 | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde | |
| The global use of the International Classification of Diseases to Perinatal Mortality (ICD-PM): A systematic review. | Prüst ZD, Kodan LR, van den Akker T, Bloemenkamp KW, Rijken MJ, Verschueren KJ | 2022-08-17 | Journal of global health | |
| The association between continuous ambulatory heart rate, heart rate variability, and 24-h rhythms of heart rate with familial longevity and aging. | Wiersema JM, Kamphuis AEP, Rohling JHT, Kervezee L, Akintola AA, Jansen SW, Slagboom PE, van Heemst D, van der Spoel E | 2022-08-16 | aging, continuous ambulatory measurements, heart rate, heart rate variability, longevity | Aging |
| Association between fat-soluble vitamins and self-reported health status: a cross-sectional analysis of the MARK-AGE cohort. | Stokes CS, Weber D, Wagenpfeil S, Stuetz W, Moreno-Villanueva M, Dollé MET, Jansen E, Gonos ES, Bernhardt J, Grubeck-Loebenstein B, Fiegl S, Sikora E, Toussaint O, Debacq-Chainiaux F, Capri M, Hervonen A, Slagboom PE, Breusing N, Frank J, Bürkle A, Franceschi C, Grune T | 2022-08-14 | Micronutrients, Plasma, Retinol, Vitamin D, α-tocopherol | The British journal of nutrition |
| MiMIR: R-shiny application to infer risk factors and endpoints from Nightingale Health’s 1H-NMR metabolomics data. | Bizzarri D, Reinders MJT, Beekman M, Slagboom PE, van den Akker EB | 2022-08-02 | Bioinformatics (Oxford, England) | |
| Systemic inflammatory markers in relation to cognitive function and measures of brain atrophy: a Mendelian randomization study. | Luo J, le Cessie S, Blauw GJ, Franceschi C, Noordam R, van Heemst D | 2022-08-01 | Cerebral cortex, Cognitive function, Cytokines, Hippocampal volume, Inflammation | GeroScience |
| The association between mitochondrial DNA abundance and stroke: A combination of multivariable-adjusted survival and Mendelian randomization analyses. | Martens LG, Luo J, Wermer MJH, Willems van Dijk K, Hägg S, Grassmann F, Noordam R, van Heemst D | 2022-08-01 | Cardiovascular diseases, Hemorrhagic stroke, Ischemic stroke, Mendelian randomization, Mitochondrial DNA copy numbers, Mitochondrial function, Reactive oxygen species | Atherosclerosis |
| Bone geometry in older adults with subclinical hypothyroidism upon levothyroxine therapy: A nested study within a randomized placebo controlled trial. | Büchi AE, Feller M, Netzer S, Blum MR, Gonzalez Rodriguez E, Collet TH, Del Giovane C, van Heemst D, Quinn T, Kearney PM, Westendorp RGJ, Gussekloo J, Mooijaart SP, Hans D, Bauer DC, Rodondi N, Aeberli D | 2022-08-01 | Bone geometry, Levothyroxine, Peripheral quantitative computational tomography, Subclinical hypothyoroidism, Volumetric bone density | Bone |
| Metabolomic predictors of phenotypic traits can replace and complement measured clinical variables in population-scale expression profiling studies. | Niehues A, Bizzarri D, Reinders MJT, Slagboom PE, van Gool AJ, van den Akker EB, 't Hoen PAC | 2022-07-31 | Clinical surrogates, Expression profiling, Meta-analysis, Metabolomics, Multi-omics, Population cohort study, Predictors, Surrogate outcomes, Surrogates, Transcriptomics | BMC genomics |
| Survival of patients who opt for dialysis versus conservative care: a systematic review and meta-analysis. | Voorend CGN, van Oevelen M, Verberne WR, van den Wittenboer ID, Dekkers OM, Dekker F, Abrahams AC, van Buren M, Mooijaart SP, Bos WJW | 2022-07-26 | conservative care, dialysis, end-stage kidney disease, mortality, systematic review | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association |
| A cluster of blood-based protein biomarkers reflecting coagulation relates to the burden of cerebral small vessel disease. | Kuipers S, Overmars LM, van Es B, de Bresser J, Bron EE, Hoefer IE, Kappelle LJ, Teunissen CE, Biessels GJ, Haitjema S | 2022-07-01 | Biomarkers, cerebral small vessel diseases, coagulation, proteins, unsupervised cluster analysis | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism |
| Preferences for in-kind and in-cash home care insurance. | de Bresser J, Knoef M, van Ooijen R | 2022-07-01 | Discrete choice experiment, Health expectations, Home care, Long-term care insurance, Saving motives, Willingness to pay | Journal of health economics |
| Coping strategies of older adults with a recent hip fracture within inpatient geriatric rehabilitation. | Scheffers-Barnhoorn MN, Sharma-Virk M, van Balen R, van Eijk M, Achterberg WP | 2022-07-01 | 2016), Coping (strategies), Netherlands Trial Register: NTR5695 (March 7, geriatric rehabilitation, hip fracture | Aging & mental health |
| From Warkworth House to the 21st century care homes: progress marked by persistent challenges. | Gordon AL, Spilsbury K, Achterberg WP, Adams R, Jones L, Goodman C | 2022-07-01 | care homes, minimum datasets, older people, primary care | Age and ageing |
| Implementing a Personalized Integrated Stepped-Care Method (STIP-Method) to Prevent and Treat Neuropsychiatric Symptoms in Persons With Dementia in Nursing Homes: Protocol for a Mixed Methods Study. | Verstraeten HMF, Ziylan C, Gerritsen DL, Huijsman R, Nakanishi M, Smalbrugge M, van der Steen JT, Zuidema SU, Achterberg WP, Bakker TJEM | 2022-06-22 | caregiver, dementia, implementation, neuropsychiatric symptoms, nursing homes, psychosocial intervention | JMIR research protocols |
| Classical risk factors for primary coronary artery disease from an aging perspective through Mendelian Randomization. | Jansen SA, Huiskens B, Trompet S, Jukema J, Mooijaart SP, Willems van Dijk K, van Heemst D, Noordam R | 2022-06-01 | Aging, Coronary artery disease, LDL cholesterol, Mendelian Randomization, Risk factors | GeroScience |
| Microinfarcts in the Deep Gray Matter on 7T MRI: Risk Factors, MRI Correlates, and Relation to Cognitive Functioning-The SMART-MR Study. | Ghaznawi R, Zwartbol MHT, de Bresser J, Kuijf HJ, Vincken KL, Rissanen I, Geerlings MI, Hendrikse J | 2022-06-01 | AJNR. American journal of neuroradiology | |
| Prevalence, risk factors, and long-term outcomes of cerebral ischemia in hospitalized COVID-19 patients – study rationale and protocol of the CORONIS study: A multicentre prospective cohort study. | van Lith TJ, Sluis WM, Wijers NT, Meijer FJ, Kamphuis-van Ulzen K, de Bresser J, Dankbaar JW, van den Heuvel FM, Antoni ML, Mulders-Manders CM, de Mast Q, van de Veerdonk FL, Klok FA, Tuladhar AM, Cannegieter SC, Wermer MJ, van der Worp HB, Huisman MV, de Leeuw FE | 2022-06-01 | COVID-19, SARS-CoV-2, ischemic stroke, silent cerebral ischemia | European stroke journal |
| Neuropsychiatric systemic lupus erythematosus is associated with a distinct type and shape of cerebral white matter hyperintensities. | Inglese F, Jaarsma-Coes MG, Steup-Beekman GM, Monahan R, Huizinga T, van Buchem MA, Ronen I, de Bresser J | 2022-05-30 | MRI, SLE, brain, white matter hyperintensity | Rheumatology (Oxford, England) |
| Distancing Measures and Challenges Discussed by COVID-19 Outbreak Teams of Dutch Nursing Homes: The COVID-19 MINUTES Study. | van Tol LS, Smaling HJA, Meester W, Janus SIM, Zuidema SU, de Waal MWM, Caljouw MAA, Achterberg WP | 2022-05-27 | COVID-19, distancing, infection prevention and control, isolation, nursing homes, qualitative | International journal of environmental research and public health |
| Linking a peer coach physical activity intervention for older adults to a primary care referral scheme. | van de Vijver PL, Schalkwijk FH, Numans ME, Slaets JPJ, van Bodegom D | 2022-05-17 | Exercise referral, Lifestyle, Peer coaching, Physical activity, Primary care | BMC primary care |
| No Effect of Levothyroxine on Hemoglobin in Older Adults With Subclinical Hypothyroidism: Pooled Results From 2 Randomized Controlled Trials. | Du Puy RS, Poortvliet RKE, Mooijaart SP, Stott DJ, Quinn T, Sattar N, Westendorp RGJ, Kearney PM, McCarthy VJC, Byrne S, Rodondi N, Baretella O, Collet TH, van Heemst D, Dekkers OM, Jukema JW, Smit JWA, Gussekloo J, den Elzen WPJ | 2022-05-17 | RCT, anemia, older adults, subclinical hypothyroidism, thyroid | The Journal of clinical endocrinology and metabolism |
| Prospective individual patient data meta-analysis of two randomized trials on convalescent plasma for COVID-19 outpatients. | Millat-Martinez P, Gharbharan A, Alemany A, Rokx C, Geurtsvankessel C, Papageorgiou G, van Geloven N, Jordans C, Groeneveld G, Swaneveld F, van der Schoot E, Corbacho-Monné M, Ouchi D, Piccolo Ferreira F, Malchair P, Videla S, García García V, Ruiz-Comellas A, Ramírez-Morros A, Rodriguez Codina J, Amado Simon R, Grifols JR, Blanco J, Blanco I, Ara J, Bassat Q, Clotet B, Baro B, Troxel A, Zwaginga JJ, Mitjà O, Rijnders BJA | 2022-05-11 | Nature communications | |
| Depression and Inflammatory Bowel Disease: A Bidirectional Two-sample Mendelian Randomization Study. | Luo J, Xu Z, Noordam R, van Heemst D, Li-Gao R | 2022-05-10 | Depression, Mendelian randomization, inflammatory bowel disease | Journal of Crohn's & colitis |
| Visual impairment as a predictor for deterioration in functioning: the Leiden 85-plus Study. | Verbeek E, Drewes YM, Gussekloo J | 2022-05-06 | Cohort study, Functioning, Mortality, Older adults, Prediction, Quality of life, Visual impairment | BMC geriatrics |
| Assessment of the appropriateness of cardiovascular preventive medication in older people: using the RAND/UCLA Appropriateness Method. | van der Ploeg MA, Poortvliet RKE, Achterberg WP, Mooijaart SP, Gussekloo J, Drewes YM | 2022-05-05 | Cardiovascular diseases, Clinical decision-making, Drug therapy, Geriatrics, Preventive medicine | BMC geriatrics |
| Deficits in Geriatric Assessment Associate With Disease Activity and Burden in Older Patients With Inflammatory Bowel Disease. | Asscher VER, Waars SN, van der Meulen-de Jong AE, Stuyt RJL, Baven-Pronk AMC, van der Marel S, Jacobs RJ, Haans JJL, Meijer LJ, Klijnsma-Slagboom JD, Duin MH, Peters MER, Lee-Kong FVYL, Provoost NE, Tijdeman F, van Dijk KT, Wieland MWM, Verstegen MGM, van der Meijs ME, Maan ADI, van Deudekom FJ, Mooijaart SP, Maljaars PWJ | 2022-05-01 | Crohn’s Disease, Elderly, Frailty, Geriatric Assessment, Ulcerative Colitis | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association |
| Dependency of R2 and R2 * relaxation on Gd-DTPA concentration in arterial blood: Influence of hematocrit and magnetic field strength. | van Dorth D, Venugopal K, Poot DHJ, Hirschler L, de Bresser J, Smits M, Hernandez-Tamames JA, Debacker CS, van Osch MJP | 2022-05-01 | arterial input function, dynamic susceptibility contrast MRI, hematocrit dependency, magnetic field strength, oxygen saturation, simulations | NMR in biomedicine |
| Nurse-Physician Communication Around Identifying Palliative Care Needs in Nursing Home Residents. | van der Steen JT, Jongen EA, Lemos Dekker N, Bagchus L, Pasman HRW, Onwuteaka-Philipsen BD, Achterberg WP | 2022-05-01 | Journal of the American Medical Directors Association | |
| Interprofessional Collaboration in Long-Term Care and Rehabilitation: A Systematic Review. | Doornebosch AJ, Smaling HJA, Achterberg WP | 2022-05-01 | Interprofessional collaboration, barriers, elderly, facilitators, geriatric, interdisciplinary, long-term care, rehabilitation | Journal of the American Medical Directors Association |
| Activities for Residents of Dutch Nursing Homes during the COVID-19 Pandemic: A Qualitative Study. | Smeitink MMP, Smaling HJA, van Tol LS, Haaksma ML, Caljouw MAA, Achterberg WP | 2022-04-30 | COVID-19, SARS-Cov-2, dementia, geriatric care, long-term care, meaningful activities, nursing home, pandemic | International journal of environmental research and public health |
| Types, Aspects, and Impact of Relocation Initiatives Deployed within and between Long-Term Care Facilities: A Scoping Review. | Broekharst DSE, Brouwers MPJ, Stoop A, Achterberg WP, Caljouw MAA | 2022-04-14 | long-term care, relocation, relocation initiative, scoping review, transfer, transition | International journal of environmental research and public health |
| Job Demands, Work Functioning and Mental Health in Dutch Nursing Home Staff during the COVID-19 Outbreak: A Cross-Sectional Multilevel Study. | van Dijk Y, Janus SIM, de Boer MR, Achterberg WP, Roelen CAM, Zuidema SU | 2022-04-06 | COVID-19, burnout, depressive symptoms, job demands, nursing homes, work functioning | International journal of environmental research and public health |
| DNA methylation in peripheral tissues and left-handedness. | Odintsova VV, Suderman M, Hagenbeek FA, Caramaschi D, Hottenga JJ, Pool R, Dolan CV, Ligthart L, van Beijsterveldt CEM, Willemsen G, de Geus EJC, Beck JJ, Ehli EA, Cuellar-Partida G, Evans DM, Medland SE, Relton CL, Boomsma DI, van Dongen J | 2022-04-04 | Scientific reports | |
| Great saves or near misses? Severe maternal outcome in Metro East, South Africa: A region-wide population-based case-control study. | Heitkamp A, Vollmer Murray L, van den Akker T, Gebhardt GS, Sandberg EM, van Roosmalen J, Ter Wee MM, de Vries JI, Theron G | 2022-04-01 | South Africa, case control, maternal morbidity, maternal mortality, maternal near miss, population-based, severe maternal outcome | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics |
| WHO next-generation partograph: revolutionary steps towards individualised labour care? | Maaløe N, van Roosmalen J, Dmello B, Kwast B, van den Akker T, Housseine N, Kujabi M, Meguid T, Kidanto H | 2022-04-01 | BJOG : an international journal of obstetrics and gynaecology | |
| Nationwide confidential enquiries into maternal deaths because of obstetric hemorrhage in the Netherlands between 2006 and 2019. | Ramler PI, Beenakkers ICM, Bloemenkamp KWM, Van der Bom JG, Braams-Lisman BAM, Cornette JMJ, Kallianidis AF, Kuppens SMI, Rietveld AL, Schaap TP, Schutte JM, Stekelenburg J, Zwart JJ, Van den Akker T | 2022-04-01 | confidential enquiry, improvable care, lessons learned, maternal mortality, obstetric hemorrhage, postpartum hemorrhage | Acta obstetricia et gynecologica Scandinavica |
| Confidential enquiry into maternal deaths in the Netherlands, 2006-2018. | Kallianidis AF, Schutte JM, Schuringa LEM, Beenakkers ICM, Bloemenkamp KWM, Braams-Lisman BAM, Cornette J, Kuppens SM, Rietveld AL, Schaap T, Stekelenburg J, Zwart JJ, van den Akker T | 2022-04-01 | confidential enquiry, maternal health, maternal mortality, the Netherlands | Acta obstetricia et gynecologica Scandinavica |
| “Too much, too late”: data on stillbirths to improve interpretation of caesarean section rates. | Zethof S, Christou A, Benova L, van Roosmalen J, van den Akker T | 2022-04-01 | Bulletin of the World Health Organization | |
| Mortality risk for different presenting complaints amongst older patients assessed with the Manchester triage system. | Lucke JA, Mooijaart SP, Conroy S, Blomaard LC, De Groot B, Nickel CH | 2022-04-01 | Emergency department, Manchester triage system, Mortality, Non-specific complaints, Older patients, Triage | European geriatric medicine |
| Providing care for older adults in the Emergency Department: expert clinical recommendations from the European Task Force on Geriatric Emergency Medicine. | Lucke JA, Mooijaart SP, Heeren P, Singler K, McNamara R, Gilbert T, Nickel CH, Castejon S, Mitchell A, Mezera V, Van der Linden L, Lim SE, Thaur A, Karamercan MA, Blomaard LC, Dundar ZD, Chueng KY, Islam F, de Groot B, Conroy S | 2022-04-01 | Acute care, Emergency Medicine, Frailty, Geriatric Emergency Medicine, Geriatrics, Guidelines | European geriatric medicine |
| Geriatric characteristics and the risk of drug-related hospital admissions in older Emergency Department patients. | Luttikhuis HM, Blomaard LC, van der Kaaij MAE, Gombert-Handoko KB, de Groot B, Mooijaart SP | 2022-04-01 | Adverse drug events, Emergency Department, Frailty, Hospitalization, Older adults | European geriatric medicine |
| Geriatric assessment and treatment outcomes in a Dutch cohort of older patients with potentially curable esophageal cancer. | van Holstein Y, Trompet S, van Deudekom FJ, van Munster B, de Glas NA, van den Bos F, Uit den Boogaard A, van der Elst MJT, van der Kaaij MAE, Neelis KJ, Langers AMJ, Slingerland M, Portielje JEA, Mooijaart SP | 2022-04-01 | Esophageal cancer, chemoradiotherapy, geriatric assessment, geriatric oncology, mortality, treatment discontinuation | Acta oncologica (Stockholm, Sweden) |
| Effect of Intramuscular vs Intra-articular Glucocorticoid Injection on Pain Among Adults With Knee Osteoarthritis: The KIS Randomized Clinical Trial. | Wang Q, Mol MF, Bos PK, Dorleijn DMJ, Vis M, Gussekloo J, Bindels PJE, Runhaar J, Bierma-Zeinstra SMA | 2022-04-01 | JAMA network open | |
| Developing country-specific questions about end-of-life care for nursing home residents with advanced dementia using the nominal group technique with family caregivers. | Bavelaar L, Nicula M, Morris S, Kaasalainen S, Achterberg WP, Loucka M, Vlckova K, Thompson G, Cornally N, Hartigan I, Harding A, Preston N, Walshe C, Cousins E, Dening KH, De Vries K, Brazil K, van der Steen JT | 2022-04-01 | Dementia, End-of-life care, Family caregiver, Nursing home, Patient engagement, Shared decision making | Patient education and counseling |
| Mandatory vaccination against COVID-19 for health and social care workers caring for older people. | Gordon AL, Achterberg WP, van Delden JJM | 2022-04-01 | COVID-19, ethics, frailty, older people, vaccination | Age and ageing |
| Fat metabolism is associated with telomere length in six population-based studies. | van der Spek A, Karamujić-Čomić H, Pool R, Bot M, Beekman M, Garmaeva S, Arp PP, Henkelman S, Liu J, Alves AC, Willemsen G, van Grootheest G, Aubert G, Ikram MA, Jarvelin MR, Lansdorp P, Uitterlinden AG, Zhernakova A, Slagboom PE, Penninx BWJH, Boomsma DI, Amin N, van Duijn CM | 2022-03-31 | Human molecular genetics | |
| Feasibility of establishing a Canadian Obstetric Survey System (CanOSS) for severe maternal morbidity: a study protocol. | D'Souza R, Seymour RJ, Knight M, Dzakpasu S, Joseph KS, Thorne S, Ospina MB, Barrett J, Cook J, Fell DB, Scott H, Metcalfe A, van den Akker T, Lapinsky S, Skeith L, Murray-Davis B, Shah P, Forte M, Ashraf R, Chundamala J, Hutchinson SA, Chen KK, Malhamé I | 2022-03-23 | adult intensive & critical care, audit, maternal medicine, obstetrics | BMJ open |
| Timing of objectively-collected physical activity in relation to body weight and metabolic health in sedentary older people: a cross-sectional and prospective analysis. | Albalak G, Stijntjes M, Wijsman CA, Slagboom PE, van der Ouderaa FJ, Mooijaart SP, van Heemst D, Noordam R | 2022-03-01 | International journal of obesity (2005) | |
| Characteristics and outcomes of older patients hospitalised for COVID-19 in the first and second wave of the pandemic in The Netherlands: the COVID-OLD study. | Smits RAL, Trompet S, van der Linden CMJ, van der Bol JM, Jansen SWM, Polinder-Bos HA, Willems HC, Barten DG, Blomaard LC, de Boer MGJ, van Deudekom FJA, Ellerbroek JLJ, Festen J, van de Glind EMM, Kampschreur LM, Karimi O, Kroon B, van Lanen MGJA, Lucke JA, Maas HAAM, Mattace-Raso FUS, van Munster BC, Reijerse L, Robben SHM, Ruiter R, Schouten HJ, Spies PE, Wassenburg A, Wijngaarden MA, Mooijaart SP | 2022-03-01 | COVID-19, frailty, in-hospital mortality, second pandemic wave | Age and ageing |
| Geriatric emergency medicine-a model for frailty friendly healthcare. | Mooijaart SP, Carpenter CR, Conroy SP | 2022-03-01 | emergency medicine, evidence-based medicine, frailty, older people | Age and ageing |
| Maintaining meaningful activities for persons with dementia during transitions of care: A systematic review. | Groenendaal M, Smaling HJA, Achterberg WP, Caljouw MAA | 2022-03-01 | Dementia, Meaningful activities, Person-centered care, Systematic review, Transitions of care | Geriatric nursing (New York, N.Y.) |
| ‘Don’t let the trial kill the intervention’: how can researchers and care home teams implement complex intervention trials in care homes? | Shenkin SD, Gordon AL, Johnston L, Henderson C, Achterberg WP | 2022-03-01 | Care homes, older people, systematic review, trials | Age and ageing |
| Characteristics and outcomes of older patients hospitalised for COVID-19 in the first and second wave of the pandemic in The Netherlands: the COVID-OLD study | Smits RAL, Trompet S, van der Linden CMJ, van der Bol JM, Jansen SWM, Polinder-Bos HA, Willems HC, Barten DG, Blomaard LC, de Boer MGJ, van Deudekom FJA, Ellerbroek JLJ, Festen J, van de Glind EMM, Kampschreur LM, Karimi O, Kroon B, van Lanen MGJA, Lucke JA, Maas HAAM, Mattace-Raso FUS, van Munster BC, Reijerse L, Robben SHM, Ruiter R, Schouten HJ, Spies PE, Wassenburg A, Wijngaarden MA, Mooijaart SP | 2022-03-01 | Age and Ageing | |
| Circulating angiopoietin-2 and angiogenic microRNAs associate with cerebral small vessel disease and cognitive decline in older patients reaching end-stage renal disease. | Bijkerk R, Kallenberg MH, Zijlstra LE, van den Berg BM, de Bresser J, Hammer S, Bron EE, Achterberg H, van Buchem MA, Berkhout-Byrne NC, Bos WJW, van Heemst D, Rabelink TJ, van Zonneveld AJ, van Buren M, Mooijaart S | 2022-02-25 | ageing, angiopoietin-2, cerebral small vessel disease, cognitive dysfunction, microRNAs | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association |
| Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS. | Hop PJ, Zwamborn RAJ, Hannon E, Shireby GL, Nabais MF, Walker EM, van Rheenen W, van Vugt JJFA, Dekker AM, Westeneng HJ, Tazelaar GHP, van Eijk KR, Moisse M, Baird D, Al Khleifat A, Iacoangeli A, Ticozzi N, Ratti A, Cooper-Knock J, Morrison KE, Shaw PJ, Basak AN, Chiò A, Calvo A, Moglia C, Canosa A, Brunetti M, Grassano M, Gotkine M, Lerner Y, Zabari M, Vourc'h P, Corcia P, Couratier P, Mora Pardina JS, Salas T, Dion P, Ross JP, Henderson RD, Mathers S, McCombe PA, Needham M, Nicholson G, Rowe DB, Pamphlett R, Mather KA, Sachdev PS, Furlong S, Garton FC, Henders AK, Lin T, Ngo ST, Steyn FJ, Wallace L, Williams KL, Neto MM, Cauchi RJ, Blair IP, Kiernan MC, Drory V, Povedano M, de Carvalho M, Pinto S, Weber M, Rouleau GA, Silani V, Landers JE, Shaw CE, Andersen PM, McRae AF, van Es MA, Pasterkamp RJ, Wray NR, McLaughlin RL, Hardiman O, Kenna KP, Tsai E, Runz H, Al-Chalabi A, van den Berg LH, Van Damme P, Mill J, Veldink JH | 2022-02-23 | Science translational medicine | |
| Severe COVID-19 in pregnancy is almost exclusively limited to unvaccinated women – time for policies to change. | Engjom H, van den Akker T, Aabakke A, Ayras O, Bloemenkamp K, Donati S, Cereda D, Overtoom E, Knight M | 2022-02-01 | The Lancet regional health. Europe | |
| Commentary on the EMA reflection paper on the pharmaceutical development of medicines for use in the older population. | van Riet-Nales DA, van den Bemt B, van Bodegom D, Cerreta F, Dooley B, Eggenschwyler D, Hirschlérova B, Jansen PAF, Karapinar-Çarkit F, Moran A, Span J, Stegemann S, Sundberg K | 2022-02-01 | drug delivery, drug regulation, drug safety, health policy, public health | British journal of clinical pharmacology |
| Management of post-acute COVID-19 patients in geriatric rehabilitation: EuGMS guidance. | van Haastregt JCM, Everink IHJ, Schols JMGA, Grund S, Gordon AL, Poot EP, Martin FC, O'Neill D, Petrovic M, Bachmann S, van Balen R, van Dam van Isselt L, Dockery F, Holstege MS, Landi F, Pérez LM, Roquer E, Smalbrugge M, Achterberg WP | 2022-02-01 | COVID-19, Geriatric rehabilitation, Guidance, Post-acute care, Quality assurance | European geriatric medicine |
| Perceptions of peer contraceptive use and its influence on contraceptive method use and choice among young women and men in Kenya: a quantitative cross-sectional study. | Calhoun LM, Mirzoyants A, Thuku S, Benova L, Delvaux T, van den Akker T, McGuire C, Onyango B, Speizer IS | 2022-01-21 | Condom, Contraceptives, Family planning, Kenya, Peer, Social norms, Youth | Reproductive health |
| Thyroid Function and Risk of Anemia: A Multivariable-Adjusted and Mendelian Randomization Analysis in the UK Biobank. | van Vliet NA, Kamphuis AEP, den Elzen WPJ, Blauw GJ, Gussekloo J, Noordam R, van Heemst D | 2022-01-18 | Mendelian randomization, UK Biobank, anemia, thyroid status | The Journal of clinical endocrinology and metabolism |
| Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression. | Jonkman TH, Dekkers KF, Slieker RC, Grant CD, Ikram MA, van Greevenbroek MMJ, Franke L, Veldink JH, Boomsma DI, Slagboom PE, Consortium BIOS, Heijmans BT | 2022-01-14 | Genome biology | |
| Positive health during the COVID-19 pandemic: a survey among community-dwelling older individuals in the Netherlands. | Moens IS, van Gerven LJ, Debeij SM, Bakker CH, Moester MJC, Mooijaart SP, van der Pas S, Vangeel M, Gussekloo J, Drewes YM, Elzen WPJD | 2022-01-13 | Bodily functions, COVID-19, Daily functioning, Meaningfulness, Mental well-being, Online questionnaire, Quality of life, Social participation | BMC geriatrics |
| Circulating miRNAs and Vascular Injury Markers Associate with Cardiovascular Function in Older Patients Reaching End-Stage Kidney Disease. | Zhao Q, Nooren SJL, Zijlstra LE, Westenberg JJM, Kroft LJM, Jukema JW, Berkhout-Byrne NC, Rabelink TJ, van Zonneveld AJ, van Buren M, Mooijaart SP, Bijkerk R | 2022-01-10 | angiopoietin-2, cardiovascular disease (CVD), end-stage kidney disease (ESKD), miRNAs, pulse wave velocity (PWV) | Non-coding RNA |
| Declining daily functioning as a prelude to a hip fracture in older persons-an individual patient data meta-analysis. | Ravensbergen WM, Blom JW, Kingston A, Robinson L, Kerse N, Teh RO, Groenwold RHH, Gussekloo J | 2022-01-06 | disability, function, hip fracture, older people | Age and ageing |
| Making progress: but a way to go-the age and ageing care-home collection. | Gordon AL, Bennett C, Goodman C, Achterberg WP | 2022-01-06 | care homes, methodology, older people, research | Age and ageing |
| Do we AGREE on the targets of antihypertensive drug treatment in older adults: a systematic review of guidelines on primary prevention of cardiovascular diseases. | Bogaerts JMK, von Ballmoos LM, Achterberg WP, Gussekloo J, Streit S, van der Ploeg MA, Drewes YM, Poortvliet RKE | 2022-01-06 | antihypertensive drug therapy, guidelines, older people, primary cardiovascular prevention, systematic review | Age and ageing |
| The Impact of Social Distancing Due to the COVID-19 Pandemic on People with Dementia, Family Carers and Healthcare Professionals: A Qualitative Study. | Smaling HJA, Tilburgs B, Achterberg WP, Visser M | 2022-01-04 | COVID-19, dementia, family carers, home care, long-term care, social isolation | International journal of environmental research and public health |
| 1H-NMR metabolomics-based surrogates to impute common clinical risk factors and endpoints. | Bizzarri D, Reinders MJT, Beekman M, Slagboom PE, Bbmri-Nl, van den Akker EB | 2022-01-01 | (1)H-NMR metabolomics, Association studies, Epidemiology, Missing values, Regression models, Surrogate clinical variables | EBioMedicine |
| Associations of metabolomic profiles with circulating vitamin E and urinary vitamin E metabolites in middle-aged individuals. | Luo J, Hashimoto Y, Martens LG, Meulmeester FL, Ashrafi N, Mook-Kanamori DO, Rosendaal FR, Jukema JW, van Dijk KW, Mills K, le Cessie S, Noordam R, van Heemst D | 2022-01-01 | Carboxymethyl-hydroxychroman, Lipid profile, Tocopheronolactone hydroquinone, Vitamin E | Nutrition (Burbank, Los Angeles County, Calif.) |
| Effect of breathing on venous return during delayed cord clamping: an observational study. | Brouwer E, Knol R, Kroushev A, Van Den Akker T, Hooper SB, Roest AA, Te Pas AB | 2022-01-01 | cardiology, neonatology, physiology | Archives of disease in childhood. Fetal and neonatal edition |
| SARS-CoV-2 infection in pregnancy during the first wave of COVID-19 in the Netherlands: a prospective nationwide population-based cohort study (NethOSS). | Overtoom EM, Rosman AN, Zwart JJ, Vogelvang TE, Schaap TP, van den Akker T, Bloemenkamp K | 2022-01-01 | coronavirus disease 2019, obstetric surveillance system, pregnancy, pregnancy complications, severe acute respiratory syndrome coronavirus 2 | BJOG : an international journal of obstetrics and gynaecology |
| Clinical value of early assessment of hyperfibrinolysis by rotational thromboelastometry during postpartum hemorrhage for the prediction of severity of bleeding: A multicenter prospective cohort study in the Netherlands. | Tahitu M, Ramler PI, Gillissen A, Caram-Deelder C, Henriquez DDCA, de Maat MPM, Duvekot JJ, Eikenboom J, Bloemenkamp KWM, van den Akker T, van der Bom JG | 2022-01-01 | ROTEM®, hyperfibrinolysis, postpartum hemorrhage, rotational thromboelastometry, severity of bleeding | Acta obstetricia et gynecologica Scandinavica |
| Evaluating Clinical Outcomes and Physiological Perspectives in Studies Investigating Respiratory Support for Babies Born at Term With or at Risk of Transient Tachypnea: A Narrative Review. | McGillick EV, Te Pas AB, van den Akker T, Keus JMH, Thio M, Hooper SB | 2022-01-01 | airway liquid, end-expiratory pressure, respiratory distress, respiratory support, transient tachypnea of the newborn | Frontiers in pediatrics |
| “I Got What I Came for”: A Qualitative Exploration into Family Planning Client Satisfaction in Dosso Region, Niger. | Calhoun LM, Maytan-Joneydi A, Nouhou AM, Benova L, Delvaux T, van den Akker T, Agali BI, Speizer IS | 2022-01-01 | Niger, client satisfaction, contraception, family planning | Open access journal of contraception |
| Contraceptive method use trajectories among young women in Kenya: A qualitative study. | Calhoun LM, Mandal M, Onyango B, Waga E, McGuire C, Zulu EM, van den Akker T, Benova L, Delvaux T, Speizer IS | 2022-01-01 | contraception, family planning, life course, method choice, youth | Frontiers in global women's health |
| “Separated during the first hours”-Postnatal care for women and newborns during the COVID-19 pandemic: A mixed-methods cross-sectional study from a global online survey of maternal and newborn healthcare providers. | Semaan A, Dey T, Kikula A, Asefa A, Delvaux T, Langlois EV, van den Akker T, Benova L | 2022-01-01 | PLOS global public health | |
| No increase in use of hospitals for childbirth in Tanzania over 25 years: Accumulation of inequity among poor, rural, high parity women. | Straneo M, Beňová L, van den Akker T, Pembe AB, Smekens T, Hanson C | 2022-01-01 | PLOS global public health | |
| HPV type-specific distribution among family members and linen in households of cutaneous wart patients. | Ghorzang E, de Koning MNC, Bouwes Bavinck JN, Gussekloo J, Quint KD, Goeman JJ, Feltkamp MCW, Bruggink SC, Eekhof JAH | 2022-01-01 | Journal of the European Academy of Dermatology and Venereology : JEADV | |
| Association of cognitive function with increased risk of cancer death and all-cause mortality: Longitudinal analysis, systematic review, and meta-analysis of prospective observational studies. | Rostamian S, le Cessie S, Marijt KA, Jukema JW, Mooijaart SP, van Buchem MA, van Hall T, Gussekloo J, Trompet S | 2022-01-01 | PloS one | |
| Incorporating Baseline Outcome Data in Individual Participant Data Meta-Analysis of Non-randomized Studies. | Syrogiannouli L, Wildisen L, Meuwese C, Bauer DC, Cappola AR, Gussekloo J, den Elzen WPJ, Trompet S, Westendorp RGJ, Jukema JW, Ferrucci L, Ceresini G, Åsvold BO, Chaker L, Peeters RP, Imaizumi M, Ohishi W, Vaes B, Völzke H, Sgarbi JA, Walsh JP, Dullaart RPF, Bakker SJL, Iacoviello M, Rodondi N, Del Giovane C | 2022-01-01 | baseline imbalance, cohorts, continuous outcome, individual participant data, non-randomized studies | Frontiers in psychiatry |
| MRI-Based Classification of Neuropsychiatric Systemic Lupus Erythematosus Patients With Self-Supervised Contrastive Learning. | Inglese F, Kim M, Steup-Beekman GM, Huizinga TWJ, van Buchem MA, de Bresser J, Kim DS, Ronen I | 2022-01-01 | Systemic Lupus Erythematosus, cohort studies, magnetic resonance imaging, neuroimaging, unsupervised machine learning | Frontiers in neuroscience |
| Different cardiovascular risk factors are related to distinct white matter hyperintensity MRI phenotypes in older adults. | Keller JA, Kant IMJ, Slooter AJC, van Montfort SJT, van Buchem MA, van Osch MJP, Hendrikse J, de Bresser J | 2022-01-01 | Cardiovascular risk factors, Cerebral small vessel disease, Cognitive decline, Magnetic resonance imaging, White matter hyperintensities | NeuroImage. Clinical |
| COVID-19 Pandemic and Consecutive Changes in Geriatric Rehabilitation Structures and Processes – A Deeper Attempt to Explain the COVID Rehabilitation Paradox (Lessons to Learn to Ensure High Quality of Care in GR Services). | Grund S, Gordon AL, Bauer JM, Achterberg WP, Schols JMGA | 2022-01-01 | The journal of nutrition, health & aging | |
| Occurrence and Timing of Advance Care Planning in Persons With Dementia in General Practice: Analysis of Linked Electronic Health Records and Administrative Data. | Azizi B, Tilburgs B, van Hout HPJ, van der Heide I, Verheij RA, Achterberg WP, van der Steen JT, Joling KJ | 2022-01-01 | advance care planning, data linkage, dementia, general practice, primary care | Frontiers in public health |
| Cost-effectiveness of dementia training for caregivers in caregiver-patient dyads: A randomized controlled study. | Birkenhäger-Gillesse EG, Achterberg WP, Janus SIM, Zuidema SU, van den Hout WB | 2022-01-01 | caregivers, cost‐effectiveness, dementia, health resource, psychosocial intervention, training | Alzheimer's & dementia (New York, N. Y.) |
| Classical risk factors for primary coronary artery disease from an aging perspective through Mendelian Randomization | Jansen SA, Huiskens B, Trompet S, Jukema J, Mooijaart SP, Willems van Dijk K, van Heemst D, Noordam R | 2021-12-21 | GeroScience | |
| Diet-Derived Antioxidants Do Not Decrease Risk of Ischemic Stroke: A Mendelian Randomization Study in 1 Million People. | Martens LG, Luo J, Willems van Dijk K, Jukema JW, Noordam R, van Heemst D | 2021-12-07 | antioxidants, cardiovascular disease, diet, ischemic stroke, oxidative stress | Journal of the American Heart Association |
| Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour. | Mills MC, Tropf FC, Brazel DM, van Zuydam N, Vaez A, Pers TH, Snieder H, Perry JRB, Ong KK, den Hoed M, Barban N, Day FR | 2021-12-01 | Nature human behaviour | |
| Functional Performance After Complex Endovascular Aortic Repair: A Single-Center Retrospective Cohort Study. | Warmerdam BWCM, van Holstein Y, Eefting D, van Rijswijk CSP, van der Meer RW, Mooijaart SP, Hamming JF, van der Vorst JR, van Schaik J | 2021-12-01 | activities of daily living, complex aortic aneurysm repair, endovascular treatment/therapy, frailty, functional performance | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists |
| Trends in quality of care and dying perceived by family caregivers of nursing home residents with dementia 2005-2019. | Klapwijk MS, Bolt SR, Boogaard JA, Ten Koppel M, Gijsberts MH, van Leussen C, The BA, Meijers JM, Schols JM, Pasman HRW, Onwuteaka-Philipsen BD, Deliens L, Van den Block L, Mertens B, de Vet HC, Caljouw MA, Achterberg WP, van der Steen JT | 2021-12-01 | Dementia, end-of-life care, geriatrics, nursing homes, palliative care, quality of health care | Palliative medicine |
| COVID-19 management in nursing homes by outbreak teams (MINUTES) – study description and data characteristics: a qualitative study. | van Tol LS, Smaling HJA, Groothuijse JM, Doornebosch AJ, Janus SIM, Zuidema SU, Caljouw MAA, Achterberg WP, de Waal MWM | 2021-11-30 | COVID-19, health policy, infection control, public health, qualitative research | BMJ open |
| Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. | Boer CG, Hatzikotoulas K, Southam L, Stefánsdóttir L, Zhang Y, Coutinho de Almeida R, Wu TT, Zheng J, Hartley A, Teder-Laving M, Skogholt AH, Terao C, Zengini E, Alexiadis G, Barysenka A, Bjornsdottir G, Gabrielsen ME, Gilly A, Ingvarsson T, Johnsen MB, Jonsson H, Kloppenburg M, Luetge A, Lund SH, Mägi R, Mangino M, Nelissen RRGHH, Shivakumar M, Steinberg J, Takuwa H, Thomas LF, Tuerlings M, Babis GC, Cheung JPY, Kang JH, Kraft P, Lietman SA, Samartzis D, Slagboom PE, Stefansson K, Thorsteinsdottir U, Tobias JH, Uitterlinden AG, Winsvold B, Zwart JA, Smith GD, Sham PC, Thorleifsson G, Gaunt TR, Morris AP, Valdes AM, Tsezou A, Cheah KSE, Ikegawa S, Hveem K, Esko T, Wilkinson JM, Meulenbelt I, Michael Lee MT, van Meurs JBJ, Styrkársdóttir U, Zeggini E | 2021-11-24 | Cell | |
| Impact of the COVID-19 pandemic on symptoms of anxiety and depression and health-related quality of life in older patients with chronic kidney disease. | Voorend CGN, van Oevelen M, Nieberg M, Meuleman Y, Franssen CFM, Joosten H, Berkhout-Byrne NC, Abrahams AC, Mooijaart SP, Bos WJW, van Buren M | 2021-11-19 | Aged, Chronic kidney diseases, Coronavirus disease-2019 (COVID-19) pandemic, Mental health, Quality of life | BMC geriatrics |
| Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling. | van Vliet NA, Bos MM, Thesing CS, Chaker L, Pietzner M, Houtman E, Neville MJ, Li-Gao R, Trompet S, Mustafa R, Ahmadizar F, Beekman M, Bot M, Budde K, Christodoulides C, Dehghan A, Delles C, Elliott P, Evangelou M, Gao H, Ghanbari M, van Herwaarden AE, Ikram MA, Jaeger M, Jukema JW, Karaman I, Karpe F, Kloppenburg M, Meessen JMTA, Meulenbelt I, Milaneschi Y, Mooijaart SP, Mook-Kanamori DO, Netea MG, Netea-Maier RT, Peeters RP, Penninx BWJH, Sattar N, Slagboom PE, Suchiman HED, Völzke H, Willems van Dijk K, Noordam R, van Heemst D | 2021-11-03 | Coronary artery disease, Mendelian randomization, Metabolomics, Thyroid hormones | BMC medicine |
| Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure. | Wang H, Noordam R, Cade BE, Schwander K, Winkler TW, Lee J, Sung YJ, Bentley AR, Manning AK, Aschard H, Kilpeläinen TO, Ilkov M, Brown MR, Horimoto AR, Richard M, Bartz TM, Vojinovic D, Lim E, Nierenberg JL, Liu Y, Chitrala K, Rankinen T, Musani SK, Franceschini N, Rauramaa R, Alver M, Zee PC, Harris SE, van der Most PJ, Nolte IM, Munroe PB, Palmer ND, Kühnel B, Weiss S, Wen W, Hall KA, Lyytikäinen LP, O'Connell J, Eiriksdottir G, Launer LJ, de Vries PS, Arking DE, Chen H, Boerwinkle E, Krieger JE, Schreiner PJ, Sidney S, Shikany JM, Rice K, Chen YI, Gharib SA, Bis JC, Luik AI, Ikram MA, Uitterlinden AG, Amin N, Xu H, Levy D, He J, Lohman KK, Zonderman AB, Rice TK, Sims M, Wilson G, Sofer T, Rich SS, Palmas W, Yao J, Guo X, Rotter JI, Biermasz NR, Mook-Kanamori DO, Martin LW, Barac A, Wallace RB, Gottlieb DJ, Komulainen P, Heikkinen S, Mägi R, Milani L, Metspalu A, Starr JM, Milaneschi Y, Waken RJ, Gao C, Waldenberger M, Peters A, Strauch K, Meitinger T, Roenneberg T, Völker U, Dörr M, Shu XO, Mukherjee S, Hillman DR, Kähönen M, Wagenknecht LE, Gieger C, Grabe HJ, Zheng W, Palmer LJ, Lehtimäki T, Gudnason V, Morrison AC, Pereira AC, Fornage M, Psaty BM, van Duijn CM, Liu CT, Kelly TN, Evans MK, Bouchard C, Fox ER, Kooperberg C, Zhu X, Lakka TA, Esko T, North KE, Deary IJ, Snieder H, Penninx BWJH, Gauderman WJ, Rao DC, Redline S, van Heemst D | 2021-11-01 | Molecular psychiatry | |
| The burden of severe hypertensive disorders of pregnancy on perinatal outcomes: a nationwide case-control study in Suriname. | Prüst ZD, Kodan LR, van den Akker T, Bloemenkamp KWM, Rijken MJ, Verschueren KJC | 2021-11-01 | Caribbean, Latin America, South America, Suriname, adverse perinatal outcome, eclampsia, hypertensive disorders of pregnancy, perinatal mortality, preeclampsia | AJOG global reports |
| Association Between Blood Pressure Variability With Dementia and Cognitive Impairment: A Systematic Review and Meta-Analysis. | de Heus RAA, Tzourio C, Lee EJL, Opozda M, Vincent AD, Anstey KJ, Hofman A, Kario K, Lattanzi S, Launer LJ, Ma Y, Mahajan R, Mooijaart SP, Nagai M, Peters R, Turnbull D, Yano Y, Claassen JAHR, Tully PJ | 2021-11-01 | Alzheimer disease, blood pressure, cerebrovascular disorders, dementia, hemodynamics, meta-analysis, stroke | Hypertension (Dallas, Tex. : 1979) |
| Development and validation of the PORTRET tool to predict recurrence, overall survival, and other-cause mortality in older patients with breast cancer in the Netherlands: a population-based study. | van der Plas-Krijgsman WG, Giardiello D, Putter H, Steyerberg EW, Bastiaannet E, Stiggelbout AM, Mooijaart SP, Kroep JR, Portielje JEA, Liefers GJ, de Glas NA | 2021-11-01 | The lancet. Healthy longevity | |
| Goal attainment scaling with older people in general practice: A feasibility study. | van Blijswijk SC, Gussekloo J, Heijmans FM, Wind AW, den Elzen WP, Blom JW | 2021-11-01 | Care-action-plan, Community-dwelling older people, Evaluation method, General practice, Goal attainment scaling, Goal setting, Individualised care, Personalised care, Practice nurses, Primary care | International journal of nursing studies advances |
| Telephone follow-up to reduce unplanned hospital returns for older emergency department patients: A randomized trial. | van Loon-van Gaalen M, van der Linden MC, Gussekloo J, van der Mast RC | 2021-11-01 | emergency department, geriatric, older patients, post-discharge follow-up, telephone | Journal of the American Geriatrics Society |
| Association of Thyroid Dysfunction With Cognitive Function: An Individual Participant Data Analysis. | van Vliet NA, van Heemst D, Almeida OP, Åsvold BO, Aubert CE, Bae JB, Barnes LE, Bauer DC, Blauw GJ, Brayne C, Cappola AR, Ceresini G, Comijs HC, Dartigues JF, Degryse JM, Dullaart RPF, van Eersel MEA, den Elzen WPJ, Ferrucci L, Fink HA, Flicker L, Grabe HJ, Han JW, Helmer C, Huisman M, Ikram MA, Imaizumi M, de Jongh RT, Jukema JW, Kim KW, Kuller LH, Lopez OL, Mooijaart SP, Moon JH, Moutzouri E, Nauck M, Parle J, Peeters RP, Samuels MH, Schmidt CO, Schminke U, Slagboom PE, Stordal E, Vaes B, Völzke H, Westendorp RGJ, Yamada M, Yeap BB, Rodondi N, Gussekloo J, Trompet S | 2021-11-01 | JAMA internal medicine | |
| Different phenotypes of neuropsychiatric systemic lupus erythematosus are related to a distinct pattern of structural changes on brain MRI. | Inglese F, Kant IMJ, Monahan RC, Steup-Beekman GM, Huizinga TWJ, van Buchem MA, Magro-Checa C, Ronen I, de Bresser J | 2021-11-01 | Brain, Lupus erythematosus, Systemic, Magnetic resonance imaging, Phenotype | European radiology |
| Cortical cerebral microinfarcts on 7T MRI: Risk factors, neuroimaging correlates and cognitive functioning – The Medea-7T study. | Zwartbol MH, Rissanen I, Ghaznawi R, de Bresser J, Kuijf HJ, Blom K, Witkamp TD, Koek HL, Biessels GJ, Hendrikse J, Geerlings MI | 2021-11-01 | Microinfarcts, cerebrovascular disease, cognitive functioning, dementia, cardiovascular risk factors | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism |
| Validating biomarkers and models for epigenetic inference of alcohol consumption from blood. | Maas SCE, Vidaki A, Teumer A, Costeira R, Wilson R, van Dongen J, Beekman M, Völker U, Grabe HJ, Kunze S, Ladwig KH, van Meurs JBJ, Uitterlinden AG, Voortman T, Boomsma DI, Slagboom PE, van Heemst D, van der Kallen CJH, van den Berg LH, Waldenberger M, Völzke H, Peters A, Bell JT, Ikram MA, Ghanbari M, Kayser M | 2021-10-26 | Alcohol inference, Blood, DNA methylation, Epigenetics, Inference, Prediction | Clinical epigenetics |
| Inequity in uptake of hospital-based childbirth care in rural Tanzania: analysis of the 2015-16 Tanzania Demographic and Health Survey. | Straneo M, Benova L, Hanson C, Fogliati P, Pembe AB, Smekens T, van den Akker T | 2021-10-12 | Obstetrics, equity, health care utilization, health facilities, health inequalities, hospital, maternal and child health, maternal services, poverty, primary health care, rural | Health policy and planning |
| Maternal mortality: near-miss events in middle-income countries, a systematic review. | Heitkamp A, Meulenbroek A, van Roosmalen J, Gebhardt S, Vollmer L, de Vries JI, Theron G, van den Akker T | 2021-10-01 | Bulletin of the World Health Organization | |
| Design of a consensus-based geriatric assessment tailored for older chronic kidney disease patients: results of a pragmatic approach. | Voorend CGN, Joosten H, Berkhout-Byrne NC, Diepenbroek A, Franssen CFM, Bos WJW, Van Buren M, Mooijaart SP | 2021-10-01 | Aged, Chronic kidney diseases, Clinical decision-making, Consensus development, Frailty, Geriatric assessment | European geriatric medicine |
| Identical twins carry a persistent epigenetic signature of early genome programming. | van Dongen J, Gordon SD, McRae AF, Odintsova VV, Mbarek H, Breeze CE, Sugden K, Lundgren S, Castillo-Fernandez JE, Hannon E, Moffitt TE, Hagenbeek FA, van Beijsterveldt CEM, Jan Hottenga J, Tsai PC, Min JL, Hemani G, Ehli EA, Paul F, Stern CD, Heijmans BT, Slagboom PE, Daxinger L, van der Maarel SM, de Geus EJC, Willemsen G, Montgomery GW, Reversade B, Ollikainen M, Kaprio J, Spector TD, Bell JT, Mill J, Caspi A, Martin NG, Boomsma DI | 2021-09-28 | Nature communications | |
| Men’s comfort in distributing or receiving HIV self-test kits from close male social network members in Dar Es Salaam, Tanzania: baseline results from the STEP project. | Matovu JKB, Mbita G, Hamilton A, Mhando F, Sims WM, Thompson N, Komba AN, Lija J, Zhang J, van den Akker T, Duncan DT, Choko AT, Conserve DF | 2021-09-24 | HIV, HIV self-testing, Men, Social networks, Tanzania | BMC public health |
| Functional Changes of T-Cell Subsets with Age and CMV Infection. | Hassouneh F, Goldeck D, Pera A, van Heemst D, Slagboom PE, Pawelec G, Solana R | 2021-09-15 | CD57, T-cell response, aging, cytomegalovirus | International journal of molecular sciences |
| Familial longevity is associated with lower baseline bone turnover but not differences in bone turnover in response to rhTSH. | Zutinic A, Roelfsema F, Pijl H, Ballieux BE, Westendorp RGJ, Blauw GJ, van Heemst D | 2021-09-07 | bone metabolism, longevity, rhTSH, thyroid | Aging |
| Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations. | Boer CG, Hatzikotoulas K, Southam L, Stefánsdóttir L, Zhang Y, Coutinho de Almeida R, Wu TT, Zheng J, Hartley A, Teder-Laving M, Skogholt AH, Terao C, Zengini E, Alexiadis G, Barysenka A, Bjornsdottir G, Gabrielsen ME, Gilly A, Ingvarsson T, Johnsen MB, Jonsson H, Kloppenburg M, Luetge A, Lund SH, Mägi R, Mangino M, Nelissen RRGHH, Shivakumar M, Steinberg J, Takuwa H, Thomas LF, Tuerlings M, Babis GC, Cheung JPY, Kang JH, Kraft P, Lietman SA, Samartzis D, Slagboom PE, Stefansson K, Thorsteinsdottir U, Tobias JH, Uitterlinden AG, Winsvold B, Zwart JA, Davey Smith G, Sham PC, Thorleifsson G, Gaunt TR, Morris AP, Valdes AM, Tsezou A, Cheah KSE, Ikegawa S, Hveem K, Esko T, Wilkinson JM, Meulenbelt I, Lee MTM, van Meurs JBJ, Styrkársdóttir U, Zeggini E | 2021-09-02 | drug targets, effector genes, functional genomics, genetic architecture, genome-wide association meta-analysis, osteoarthritis | Cell |
| Relationships Between 24-hour LH and Testosterone Concentrations and With Other Pituitary Hormones in Healthy Older Men. | van der Spoel E, Roelfsema F, van Heemst D | 2021-09-01 | ageing, cross-correlation, luteinizing hormone, men, pituitary hormones, testosterone | Journal of the Endocrine Society |
| Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation. | Min JL, Hemani G, Hannon E, Dekkers KF, Castillo-Fernandez J, Luijk R, Carnero-Montoro E, Lawson DJ, Burrows K, Suderman M, Bretherick AD, Richardson TG, Klughammer J, Iotchkova V, Sharp G, Al Khleifat A, Shatunov A, Iacoangeli A, McArdle WL, Ho KM, Kumar A, Söderhäll C, Soriano-Tárraga C, Giralt-Steinhauer E, Kazmi N, Mason D, McRae AF, Corcoran DL, Sugden K, Kasela S, Cardona A, Day FR, Cugliari G, Viberti C, Guarrera S, Lerro M, Gupta R, Bollepalli S, Mandaviya P, Zeng Y, Clarke TK, Walker RM, Schmoll V, Czamara D, Ruiz-Arenas C, Rezwan FI, Marioni RE, Lin T, Awaloff Y, Germain M, Aïssi D, Zwamborn R, van Eijk K, Dekker A, van Dongen J, Hottenga JJ, Willemsen G, Xu CJ, Barturen G, Català-Moll F, Kerick M, Wang C, Melton P, Elliott HR, Shin J, Bernard M, Yet I, Smart M, Gorrie-Stone T, Shaw C, Al Chalabi A, Ring SM, Pershagen G, Melén E, Jiménez-Conde J, Roquer J, Lawlor DA, Wright J, Martin NG, Montgomery GW, Moffitt TE, Poulton R, Esko T, Milani L, Metspalu A, Perry JRB, Ong KK, Wareham NJ, Matullo G, Sacerdote C, Panico S, Caspi A, Arseneault L, Gagnon F, Ollikainen M, Kaprio J, Felix JF, Rivadeneira F, Tiemeier H, van IJzendoorn MH, Uitterlinden AG, Jaddoe VWV, Haley C, McIntosh AM, Evans KL, Murray A, Räikkönen K, Lahti J, Nohr EA, Sørensen TIA, Hansen T, Morgen CS, Binder EB, Lucae S, Gonzalez JR, Bustamante M, Sunyer J, Holloway JW, Karmaus W, Zhang H, Deary IJ, Wray NR, Starr JM, Beekman M, van Heemst D, Slagboom PE, Morange PE, Trégouët DA, Veldink JH, Davies GE, de Geus EJC, Boomsma DI, Vonk JM, Brunekreef B, Koppelman GH, Alarcón-Riquelme ME, Huang RC, Pennell CE, van Meurs J, Ikram MA, Hughes AD, Tillin T, Chaturvedi N, Pausova Z, Paus T, Spector TD, Kumari M, Schalkwyk LC, Visscher PM, Davey Smith G, Bock C, Gaunt TR, Bell JT, Heijmans BT, Mill J, Relton CL | 2021-09-01 | Nature genetics | |
| Clinical value of early viscoelastometric point-of-care testing during postpartum hemorrhage for the prediction of severity of bleeding: A multicenter prospective cohort study in the Netherlands. | Ramler PI, Gillissen A, Henriquez DDCA, Caram-Deelder C, Markovski AA, de Maat MPM, Duvekot JJ, Eikenboom JCJ, Bloemenkamp KWM, van Lith JMM, van den Akker T, van der Bom JG | 2021-09-01 | FIBTEM A5, blood transfusion, fibrinogen, maternal mortality, point-of-care testing, postpartum hemorrhage, rotational thromboelastometry, severe acute maternal morbidity | Acta obstetricia et gynecologica Scandinavica |
| Availability of facility resources and services and infection-related maternal outcomes in the WHO Global Maternal Sepsis Study: a cross-sectional study. | Brizuela V, Cuesta C, Bartolelli G, Abdosh AA, Abou Malham S, Assarag B, Castro Banegas R, Díaz V, El-Kak F, El Sheikh M, Pérez AM, Souza JP, Bonet M, Abalos E | 2021-09-01 | The Lancet. Global health | |
| Emergency department management of older people living with frailty: a guide for emergency practitioners. | Hogervorst VM, Buurman BM, De Jonghe A, van Oppen JD, Nickel CH, Lucke J, Blomaard LC, Thaur A, Mooijaart SP, Banerjee J, Wallace J, de Groot B, Conroy SP | 2021-09-01 | acute care, assessment, emergency department, geriatrics | Emergency medicine journal : EMJ |
| Determining preoperative brain MRI features and occurrence of postoperative delirium. | Kant IMJ, de Bresser J, Slooter AJC | 2021-09-01 | Journal of psychosomatic research | |
| Family involvement in the Namaste care family program for dementia: A qualitative study on experiences of family, nursing home staff, and volunteers. | Tasseron-Dries PEM, Smaling HJA, Doncker SMMM, Achterberg WP, van der Steen JT | 2021-09-01 | Dementia, Experiences, Family caregivers, Family involvement, Nursing home, Qualitative research, Quality of life | International journal of nursing studies |
| Can the Robson 10 Group Classification System help identify which groups of women are driving the high caesarean section rate in major private hospitals in eastern Ethiopia? A cross-sectional study. | Geze S, Tura AK, Fage SG, van den Akker T | 2021-08-26 | audit, epidemiology, obstetrics, public health | BMJ open |
| eHealth in Geriatric Rehabilitation: Systematic Review of Effectiveness, Feasibility, and Usability. | Kraaijkamp JJM, van Dam van Isselt EF, Persoon A, Versluis A, Chavannes NH, Achterberg WP | 2021-08-19 | digital health, eHealth, effectiveness, feasibility, geriatric rehabilitation, mHealth, systematic review, usability | Journal of medical Internet research |
| Trends in population health and demography. | Maaløe N, Housseine N, Meguid T, Tellier S, van Roosmalen J, Meyrowitsch DW, van den Akker T | 2021-08-14 | Lancet (London, England) | |
| The effects of single and a combination of determinants of anaemia in the very old: results from the TULIPS consortium. | Wang PC, Gussekloo J, Arai Y, Abe Y, Blom JW, Duncan R, Jagger C, Kerse N, Martin-Ruiz C, Palapar L, den Elzen WPJ | 2021-08-09 | Inflammation, Iron deficiency, Low haemoglobin levels, Renal impairment, Vitamin B12/folate deficiency | BMC geriatrics |
| Evaluating the effect of interventions for strengthening non-physician anesthetists’ education in Ethiopia: a pre- and post-evaluation study. | Asemu YM, Yigzaw T, Desta FA, Scheele F, van den Akker T | 2021-08-08 | Anesthesia, Competence, Education quality, Ethiopia, Non-physician anesthetists, Objective structured clinical examination | BMC medical education |
| Stratification of Type 2 Diabetes by Age of Diagnosis in the UK Biobank Reveals Subgroup-Specific Genetic Associations and Causal Risk Profiles. | Noordam R, Läll K, Smit RAJ, Laisk T, Metspalu A, Esko T, Milani L, Loos RJF, Mägi R, Willems van Dijk K, van Heemst D | 2021-08-01 | Diabetes | |
| Publisher Correction: Identification of 371 genetic variants for age at first sex and birth linked to externalising behavior. | Mills MC, Tropf FC, Brazel DM, van Zuydam N, Vaez A, Pers TH, Snieder H, Perry JRB, Ong KK, den Hoed M, Barban N, Day FR | 2021-08-01 | Nature human behaviour | |
| A narrative review of frailty assessment in older patients at the emergency department. | van Dam CS, Hoogendijk EO, Mooijaart SP, Smulders YM, de Vet RCW, Lucke JA, Blomaard LC, Otten RHJ, Muller M, Nanayakkara PWB, Trappenburg MC, Peters MJL | 2021-08-01 | European journal of emergency medicine : official journal of the European Society for Emergency Medicine | |
| Managing Pain and Psychosis Symptoms in Nursing Home Patients: Results from a Cluster-Randomized Controlled Trial (COSMOS). | Habiger TF, Achterberg WP, Flo-Groeneboom E, Mannseth J, Husebo BS | 2021-08-01 | Pain, dementia, nursing home, opioid analgesics, psychosis symptoms | Journal of the American Medical Directors Association |
| Measuring positive caregiving experiences in family caregivers of nursing home residents: A comparison of the Positive Experiences Scale, Gain in Alzheimer Care INstrument, and Positive Aspects of Caregiving questionnaire. | Smaling HJ, Joling KJ, Achterberg WP, Francke AL, van der Steen JT | 2021-08-01 | caregivers, dementia, internal consistency, nursing homes, positive caregiving experiences | Geriatrics & gerontology international |
| The prevalence of pain in Huntington’s disease in a large worldwide cohort. | Sprenger GP, Roos RAC, van Zwet E, Reijntjes RH, Achterberg WP, de Bot ST | 2021-08-01 | Analgesics, Huntington's disease, Pain, Pain interference, Painful conditions | Parkinsonism & related disorders |
| Health facility capacity to provide postabortion care in Afghanistan: a cross-sectional study. | Maruf F, Tappis H, Lu E, Yaqubi GS, Stekelenburg J, van den Akker T | 2021-07-28 | Afghanistan, Capacity of health services, Medical treatment, Postabortion care, Reproductive health | Reproductive health |
| Health-related quality of life and symptoms of conservative care versus dialysis in patients with end-stage kidney disease: a systematic review. | Verberne WR, van den Wittenboer ID, Voorend CGN, Abrahams AC, van Buren M, Dekker FW, van Jaarsveld BC, van Loon IN, Mooijaart SP, Ocak G, van Delden JJM, Bos WJW | 2021-07-23 | conservative care, health-related quality of life, renal dialysis, symptoms, systematic review | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association |
| Association of measures of body fat with serum alpha-tocopherol and its metabolites in middle-aged individuals. | Meulmeester FL, Luo J, Martens LG, Ashrafi N, de Mutsert R, Mook-Kanamori DO, Lamb HJ, Rosendaal FR, Willems van Dijk K, Mills K, van Heemst D, Noordam R | 2021-07-22 | Alpha tocopherol, Epidemiology, Mass spectrometry, Obesity, Subcutaneous adipose tissue, Visceral adipose tissue, Vitamin E metabolites | Nutrition, metabolism, and cardiovascular diseases : NMCD |
| Implementation of the Multidisciplinary Guideline on Chronic Pain in Vulnerable Nursing Home Residents to Improve Recognition and Treatment: A Qualitative Process Evaluation. | Akker LEVD, Waal MWM, Geels PJEM, Poot E, Achterberg WP | 2021-07-16 | guideline, implementation, nursing home, pain, pain management, pharmacotherapy audit meetings, qualitative research | Healthcare (Basel, Switzerland) |
| Dynamic clonal hematopoiesis and functional T-cell immunity in a supercentenarian. | van den Akker EB, Makrodimitris S, Hulsman M, Brugman MH, Nikolic T, Bradley T, Waisfisz Q, Baas F, Jakobs ME, de Jong D, Slagboom PE, Staal FJT, Reinders MJT, Holstege H | 2021-07-01 | Leukemia | |
| Apolipoprotein E genotype, lifestyle and coronary artery disease: Gene-environment interaction analyses in the UK Biobank population. | Bos MM, de Vries L, Rensen PC, Willems van Dijk K, Blauw GJ, van Heemst D, Noordam R | 2021-07-01 | APOE, Coronary artery disease, Fish, Gene-environment interactions, General population, PUFA, Physical activity | Atherosclerosis |
| Management of major obstetric hemorrhage prior to peripartum hysterectomy and outcomes across nine European countries. | Kallianidis AF, Maraschini A, Danis J, Colmorn LB, Deneux-Tharaux C, Donati S, Gissler M, Jakobsson M, Knight M, Kristufkova A, Lindqvist PG, Vandenberghe G, van den Akker T | 2021-07-01 | hysterectomy, peripartum period, placenta accreta, postpartum hemorrhage, pregnancy complications | Acta obstetricia et gynecologica Scandinavica |
| The Bidirectional Relationship between Vision and Cognition: A Systematic Review and Meta-analysis. | Vu TA, Fenwick EK, Gan ATL, Man REK, Tan BKJ, Gupta P, Ho KC, Reyes-Ortiz CA, Trompet S, Gussekloo J, O'Brien JM, Mueller-Schotte S, Wong TY, Tham YC, Cheng CY, Lee ATC, Rait G, Swenor BK, Varadaraj V, Brenowitz WD, Medeiros FA, Naël V, Narasimhalu K, Chen CLH, Lamoureux EL | 2021-07-01 | Bidirectional, Cognitive impairment, Dementia, Visual acuity, Visual impairment | Ophthalmology |
| White matter hyperintensities associate with cognitive slowing in patients with systemic lupus erythematosus and neuropsychiatric symptoms. | Monahan RC, Inglese F, Middelkoop H, van Buchem M, Huizinga TW, Kloppenburg M, Ronen I, Steup-Beekman GM, de Bresser J | 2021-07-01 | lupus erythematosus, magnetic resonance imaging, psychology, systemic | RMD open |
| Probable Pain on the Pain Assessment in Impaired Cognition (PAIC15) Instrument: Assessing Sensitivity and Specificity of Cut-Offs against Three Standards. | van der Steen JT, Westzaan A, Hanemaayer K, Muhamad M, de Waal MWM, Achterberg WP | 2021-06-29 | behavior observation techniques, dementia, diagnostic techniques and procedures, pain measurement | Brain sciences |
| Longitudinal changes in cerebral white matter microstructure in newly diagnosed systemic lupus erythematosus patients. | Silvagni E, Inglese F, Bortoluzzi A, Borrelli M, Goeman JJ, Revenaz A, Groppo E, Steup-Beekman GM, Huizinga TWJ, Ronen I, de Bresser J, Fainardi E, Govoni M, Ercan E | 2021-06-18 | diffusion tensor imaging, longitudinal MRI, systemic lupus erythematosus | Rheumatology (Oxford, England) |
| Genetically Determined Higher TSH Is Associated With a Lower Risk of Diabetes Mellitus in Individuals With Low BMI. | Bos MM, van Vliet NA, Mooijaart SP, Noordam R, van Heemst D | 2021-06-16 | diabetes mellitus, glucose homeostasis, hyperthyroidism, hypothyroidism, mendelian randomization, obesity, thyroid function | The Journal of clinical endocrinology and metabolism |
| Differential insulin sensitivity of NMR-based metabolomic measures in a two-step hyperinsulinemic euglycemic clamp study. | Wang W, van Dijk KW, Wijsman CA, Rozing MP, Mooijaart SP, Beekman M, Slagboom PE, Jukema JW, Noordam R, van Heemst D | 2021-06-09 | Hyperinsulinemic euglycemic clamp study, Insulin resistance, Metabolomic measures | Metabolomics : Official journal of the Metabolomic Society |
| Toxicity, Response and Survival in Older Patients with Metastatic Melanoma Treated with Checkpoint Inhibitors. | de Glas NA, Bastiaannet E, van den Bos F, Mooijaart SP, van der Veldt AAM, Suijkerbuijk KPM, Aarts MJB, van den Berkmortel FWPJ, Blank CU, Boers-Sonderen MJ, van den Eertwegh AJM, de Groot JB, Haanen JBAG, Hospers GAP, Jalving H, Piersma D, van Rijn RS, Ten Tije AJ, Vreugdenhil G, Wouters MWJM, Portielje JEA, Kapiteijn EW | 2021-06-05 | geriatric oncology, immunotherapy, melanoma, older adults, response, toxicity | Cancers |
| Ageing affects subtelomeric DNA methylation in blood cells from a large European population enrolled in the MARK-AGE study. | Bacalini MG, Reale A, Malavolta M, Ciccarone F, Moreno-Villanueva M, Dollé MET, Jansen E, Grune T, Gonos ES, Schön C, Bernhardt J, Grubeck-Loebenstein B, Sikora E, Toussaint O, Debacq-Chainiaux F, Capri M, Hervonen A, Hurme M, Slagboom PE, Breusing N, Aversano V, Tagliatesta S, Franceschi C, Blasco MA, Bürkle A, Caiafa P, Zampieri M | 2021-06-01 | Ageing, Centenarian offspring, DNA methylation, Down syndrome, Epigenetics, Subtelomere | GeroScience |
| DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan. | van Dongen J, Hagenbeek FA, Suderman M, Roetman PJ, Sugden K, Chiocchetti AG, Ismail K, Mulder RH, Hafferty JD, Adams MJ, Walker RM, Morris SW, Lahti J, Küpers LK, Escaramis G, Alemany S, Jan Bonder M, Meijer M, Ip HF, Jansen R, Baselmans BML, Parmar P, Lowry E, Streit F, Sirignano L, Send TS, Frank J, Jylhävä J, Wang Y, Mishra PP, Colins OF, Corcoran DL, Poulton R, Mill J, Hannon E, Arseneault L, Korhonen T, Vuoksimaa E, Felix JF, Bakermans-Kranenburg MJ, Campbell A, Czamara D, Binder E, Corpeleijn E, Gonzalez JR, Grazuleviciene R, Gutzkow KB, Evandt J, Vafeiadi M, Klein M, van der Meer D, Ligthart L, Kluft C, Davies GE, Hakulinen C, Keltikangas-Järvinen L, Franke B, Freitag CM, Konrad K, Hervas A, Fernández-Rivas A, Vetro A, Raitakari O, Lehtimäki T, Vermeiren R, Strandberg T, Räikkönen K, Snieder H, Witt SH, Deuschle M, Pedersen NL, Hägg S, Sunyer J, Franke L, Kaprio J, Ollikainen M, Moffitt TE, Tiemeier H, van IJzendoorn MH, Relton C, Vrijheid M, Sebert S, Jarvelin MR, Caspi A, Evans KL, McIntosh AM, Bartels M, Boomsma DI | 2021-06-01 | Molecular psychiatry | |
| Urinary oxidized, but not enzymatic vitamin E metabolites are inversely associated with measures of glucose homeostasis in middle-aged healthy individuals. | Luo J, Meulmeester FL, Martens LG, Ashrafi N, de Mutsert R, Mook-Kanamori DO, Rosendaal FR, Willems van Dijk K, le Cessie S, Mills K, Noordam R, van Heemst D | 2021-06-01 | Alpha-tocopherol, Glucose homeostasis, Insulin resistance, Vitamin E | Clinical nutrition (Edinburgh, Scotland) |
| Genetically Determined Serum Calcium Levels and Markers of Ventricular Repolarization: A Mendelian Randomization Study in the UK Biobank. | Young WJ, Warren HR, Mook-Kanamori DO, Ramírez J, van Duijvenboden S, Orini M, Tinker A, van Heemst D, Lambiase PD, Jukema JW, Munroe PB, Noordam R | 2021-06-01 | action potential, calcium, cardiovascular diseases, electrocardiography, electrolyte | Circulation. Genomic and precision medicine |
| The trans-ancestral genomic architecture of glycemic traits. | Chen J, Spracklen CN, Marenne G, Varshney A, Corbin LJ, Luan J, Willems SM, Wu Y, Zhang X, Horikoshi M, Boutin TS, Mägi R, Waage J, Li-Gao R, Chan KHK, Yao J, Anasanti MD, Chu AY, Claringbould A, Heikkinen J, Hong J, Hottenga JJ, Huo S, Kaakinen MA, Louie T, März W, Moreno-Macias H, Ndungu A, Nelson SC, Nolte IM, North KE, Raulerson CK, Ray D, Rohde R, Rybin D, Schurmann C, Sim X, Southam L, Stewart ID, Wang CA, Wang Y, Wu P, Zhang W, Ahluwalia TS, Appel EVR, Bielak LF, Brody JA, Burtt NP, Cabrera CP, Cade BE, Chai JF, Chai X, Chang LC, Chen CH, Chen BH, Chitrala KN, Chiu YF, de Haan HG, Delgado GE, Demirkan A, Duan Q, Engmann J, Fatumo SA, Gayán J, Giulianini F, Gong JH, Gustafsson S, Hai Y, Hartwig FP, He J, Heianza Y, Huang T, Huerta-Chagoya A, Hwang MY, Jensen RA, Kawaguchi T, Kentistou KA, Kim YJ, Kleber ME, Kooner IK, Lai S, Lange LA, Langefeld CD, Lauzon M, Li M, Ligthart S, Liu J, Loh M, Long J, Lyssenko V, Mangino M, Marzi C, Montasser ME, Nag A, Nakatochi M, Noce D, Noordam R, Pistis G, Preuss M, Raffield L, Rasmussen-Torvik LJ, Rich SS, Robertson NR, Rueedi R, Ryan K, Sanna S, Saxena R, Schraut KE, Sennblad B, Setoh K, Smith AV, Sparsø T, Strawbridge RJ, Takeuchi F, Tan J, Trompet S, van den Akker E, van der Most PJ, Verweij N, Vogel M, Wang H, Wang C, Wang N, Warren HR, Wen W, Wilsgaard T, Wong A, Wood AR, Xie T, Zafarmand MH, Zhao JH, Zhao W, Amin N, Arzumanyan Z, Astrup A, Bakker SJL, Baldassarre D, Beekman M, Bergman RN, Bertoni A, Blüher M, Bonnycastle LL, Bornstein SR, Bowden DW, Cai Q, Campbell A, Campbell H, Chang YC, de Geus EJC, Dehghan A, Du S, Eiriksdottir G, Farmaki AE, Frånberg M, Fuchsberger C, Gao Y, Gjesing AP, Goel A, Han S, Hartman CA, Herder C, Hicks AA, Hsieh CH, Hsueh WA, Ichihara S, Igase M, Ikram MA, Johnson WC, Jørgensen ME, Joshi PK, Kalyani RR, Kandeel FR, Katsuya T, Khor CC, Kiess W, Kolcic I, Kuulasmaa T, Kuusisto J, Läll K, Lam K, Lawlor DA, Lee NR, Lemaitre RN, Li H, Lin SY, Lindström J, Linneberg A, Liu J, Lorenzo C, Matsubara T, Matsuda F, Mingrone G, Mooijaart S, Moon S, Nabika T, Nadkarni GN, Nadler JL, Nelis M, Neville MJ, Norris JM, Ohyagi Y, Peters A, Peyser PA, Polasek O, Qi Q, Raven D, Reilly DF, Reiner A, Rivideneira F, Roll K, Rudan I, Sabanayagam C, Sandow K, Sattar N, Schürmann A, Shi J, Stringham HM, Taylor KD, Teslovich TM, Thuesen B, Timmers PRHJ, Tremoli E, Tsai MY, Uitterlinden A, van Dam RM, van Heemst D, van Hylckama Vlieg A, van Vliet-Ostaptchouk JV, Vangipurapu J, Vestergaard H, Wang T, Willems van Dijk K, Zemunik T, Abecasis GR, Adair LS, Aguilar-Salinas CA, Alarcón-Riquelme ME, An P, Aviles-Santa L, Becker DM, Beilin LJ, Bergmann S, Bisgaard H, Black C, Boehnke M, Boerwinkle E, Böhm BO, Bønnelykke K, Boomsma DI, Bottinger EP, Buchanan TA, Canouil M, Caulfield MJ, Chambers JC, Chasman DI, Chen YI, Cheng CY, Collins FS, Correa A, Cucca F, de Silva HJ, Dedoussis G, Elmståhl S, Evans MK, Ferrannini E, Ferrucci L, Florez JC, Franks PW, Frayling TM, Froguel P, Gigante B, Goodarzi MO, Gordon-Larsen P, Grallert H, Grarup N, Grimsgaard S, Groop L, Gudnason V, Guo X, Hamsten A, Hansen T, Hayward C, Heckbert SR, Horta BL, Huang W, Ingelsson E, James PS, Jarvelin MR, Jonas JB, Jukema JW, Kaleebu P, Kaplan R, Kardia SLR, Kato N, Keinanen-Kiukaanniemi SM, Kim BJ, Kivimaki M, Koistinen HA, Kooner JS, Körner A, Kovacs P, Kuh D, Kumari M, Kutalik Z, Laakso M, Lakka TA, Launer LJ, Leander K, Li H, Lin X, Lind L, Lindgren C, Liu S, Loos RJF, Magnusson PKE, Mahajan A, Metspalu A, Mook-Kanamori DO, Mori TA, Munroe PB, Njølstad I, O'Connell JR, Oldehinkel AJ, Ong KK, Padmanabhan S, Palmer CNA, Palmer ND, Pedersen O, Pennell CE, Porteous DJ, Pramstaller PP, Province MA, Psaty BM, Qi L, Raffel LJ, Rauramaa R, Redline S, Ridker PM, Rosendaal FR, Saaristo TE, Sandhu M, Saramies J, Schneiderman N, Schwarz P, Scott LJ, Selvin E, Sever P, Shu XO, Slagboom PE, Small KS, Smith BH, Snieder H, Sofer T, Sørensen TIA, Spector TD, Stanton A, Steves CJ, Stumvoll M, Sun L, Tabara Y, Tai ES, Timpson NJ, Tönjes A, Tuomilehto J, Tusie T, Uusitupa M, van der Harst P, van Duijn C, Vitart V, Vollenweider P, Vrijkotte TGM, Wagenknecht LE, Walker M, Wang YX, Wareham NJ, Watanabe RM, Watkins H, Wei WB, Wickremasinghe AR, Willemsen G, Wilson JF, Wong TY, Wu JY, Xiang AH, Yanek LR, Yengo L, Yokota M, Zeggini E, Zheng W, Zonderman AB, Rotter JI, Gloyn AL, McCarthy MI, Dupuis J, Meigs JB, Scott RA, Prokopenko I, Leong A, Liu CT, Parker SCJ, Mohlke KL, Langenberg C, Wheeler E, Morris AP, Barroso I | 2021-06-01 | Nature genetics | |
| The injustice of unfit clinical practice guidelines in low-resource realities. | Maaløe N, Ørtved AMR, Sørensen JB, Sequeira Dmello B, van den Akker T, Kujabi ML, Kidanto H, Meguid T, Bygbjerg IC, van Roosmalen J, Meyrowitsch DW, Housseine N | 2021-06-01 | The Lancet. Global health | |
| Predicting disease-related and patient-reported outcomes in older patients with breast cancer – a systematic review. | van der Plas-Krijgsman WG, de Boer AZ, de Jong P, Bastiaannet E, van den Bos F, Mooijaart SP, Liefers GJ, Portielje JEA, de Glas NA | 2021-06-01 | Breast cancer, Geriatric assessment, Geriatric oncology, Prediction | Journal of geriatric oncology |
| Prognostic Factors for Short-term Recovery of Independence in a Multistate Model for Patients With a Hip Fracture. | van der Sijp MPL, van Eijk M, Niggebrugge AHP, Putter H, Blauw GJ, Achterberg WP | 2021-06-01 | Hip fracture, independence, multistate, older patients, recovery, survival | Journal of the American Medical Directors Association |
| Management of prolonged first stage of labour in a low-resource setting: lessons learnt from rural Malawi. | Bakker W, van Dorp E, Kazembe M, Nkotola A, van Roosmalen J, van den Akker T | 2021-05-22 | Amniotomy, Augmentation of labour, Caesarean section, Cephalopelvic disproportion, Prolonged labour | BMC pregnancy and childbirth |
| Frailty is associated with in-hospital mortality in older hospitalised COVID-19 patients in the Netherlands: the COVID-OLD study. | Blomaard LC, van der Linden CMJ, van der Bol JM, Jansen SWM, Polinder-Bos HA, Willems HC, Festen J, Barten DG, Borgers AJ, Bos JC, van den Bos F, de Brouwer EJM, van Deudekom FJA, van Dijk SC, Emmelot-Vonk MH, Geels RES, van de Glind EMM, de Groot B, Hempenius L, Kamper AM, Kampschreur LM, de Koning MMM, Labots G, Looman R, Lucke JA, Maas HAAM, Mattace-Raso FUS, El Moussaoui R, van Munster BC, van Nieuwkoop C, Oosterwijk LBLE, Regtuijt MEM, Robben SHM, Ruiter R, Salarbaks AM, Schouten HJ, Smit OM, Smits RAL, Spies PE, Vreeswijk R, de Vries OJ, Wijngaarden MA, Wyers CE, Mooijaart SP | 2021-05-05 | COVID-19, SARS-CoV-2, clinical frailty scale, frailty, older adults | Age and ageing |
| The impact of pain on the course of ADL functioning in patients with dementia. | van Dalen-Kok AH, Pieper MJC, de Waal MWM, van der Steen JT, Scherder EJA, Achterberg WP | 2021-05-05 | activities of daily living, dementia, longitudinal study, nursing home, older people, pain | Age and ageing |
| The COVID rehabilitation paradox: why we need to protect and develop geriatric rehabilitation services in the face of the pandemic. | Grund S, Gordon AL, Bauer JM, Achterberg WP, Schols JMGA | 2021-05-05 | COVID-19, Geriatric Rehabilitation, Pandemic, Paradoxon, older people | Age and ageing |
| Metabolic biomarker profiling for identification of susceptibility to severe pneumonia and COVID-19 in the general population. | Julkunen H, Cichońska A, Slagboom PE, Würtz P | 2021-05-04 | biomarkers, covid-19, epidemiology, global health, human, medicine, pneumonia | eLife |
| Lifestyle Risk Score: handling missingness of individual lifestyle components in meta-analysis of gene-by-lifestyle interactions. | Xu H, Schwander K, Brown MR, Wang W, Waken RJ, Boerwinkle E, Cupples LA, de Las Fuentes L, van Heemst D, Osazuwa-Peters O, de Vries PS, van Dijk KW, Sung YJ, Zhang X, Morrison AC, Rao DC, Noordam R, Liu CT | 2021-05-01 | European journal of human genetics : EJHG | |
| Status of institutional-level respectful maternity care: Results from the national Ethiopia EmONC assessment. | Sheferaw ED, Bakker R, Taddele T, Geta A, Kim YM, van den Akker T, Stekelenburg J | 2021-05-01 | Ethiopia, Mistreatment, Respectful maternity care | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics |
| Clinical determinants of low handgrip strength and its decline in the oldest old: the Leiden 85-plus Study. | Ling CHY, Gussekloo J, Trompet S, Meskers CGM, Maier AB | 2021-05-01 | Cognitive function, Muscle strength, Physical fitness, Sex differences | Aging clinical and experimental research |
| Preoperative MRI brain phenotypes are related to postoperative delirium in older individuals. | Kant IMJ, Slooter AJC, Jaarsma-Coes M, van Montfort SJT, Witkamp TD, Pasma W, Hendrikse J, de Bresser J | 2021-05-01 | Brain phenotypes, Delirium, Encephalopathy, MRI | Neurobiology of aging |
| Daily garden use and quality of life in persons with advanced dementia living in a nursing home: A feasibility study. | van der Velde-van Buuringen M, Achterberg WP, Caljouw MAA | 2021-05-01 | behaviour, dementia, gardens, nursing homes, quality of life | Nursing open |
| Genome-wide association study of circulating interleukin 6 levels identifies novel loci. | Ahluwalia TS, Prins BP, Abdollahi M, Armstrong NJ, Aslibekyan S, Bain L, Jefferis B, Baumert J, Beekman M, Ben-Shlomo Y, Bis JC, Mitchell BD, de Geus E, Delgado GE, Marek D, Eriksson J, Kajantie E, Kanoni S, Kemp JP, Lu C, Marioni RE, McLachlan S, Milaneschi Y, Nolte IM, Petrelis AM, Porcu E, Sabater-Lleal M, Naderi E, Seppälä I, Shah T, Singhal G, Standl M, Teumer A, Thalamuthu A, Thiering E, Trompet S, Ballantyne CM, Benjamin EJ, Casas JP, Toben C, Dedoussis G, Deelen J, Durda P, Engmann J, Feitosa MF, Grallert H, Hammarstedt A, Harris SE, Homuth G, Hottenga JJ, Jalkanen S, Jamshidi Y, Jawahar MC, Jess T, Kivimaki M, Kleber ME, Lahti J, Liu Y, Marques-Vidal P, Mellström D, Mooijaart SP, Müller-Nurasyid M, Penninx B, Revez JA, Rossing P, Räikkönen K, Sattar N, Scharnagl H, Sennblad B, Silveira A, Pourcain BS, Timpson NJ, Trollor J, van Dongen J, Van Heemst D, Visvikis-Siest S, Vollenweider P, Völker U, Waldenberger M, Willemsen G, Zabaneh D, Morris RW, Arnett DK, Baune BT, Boomsma DI, Chang YC, Deary IJ, Deloukas P, Eriksson JG, Evans DM, Ferreira MA, Gaunt T, Gudnason V, Hamsten A, Heinrich J, Hingorani A, Humphries SE, Jukema JW, Koenig W, Kumari M, Kutalik Z, Lawlor DA, Lehtimäki T, März W, Mather KA, Naitza S, Nauck M, Ohlsson C, Price JF, Raitakari O, Rice K, Sachdev PS, Slagboom E, Sørensen TIA, Spector T, Stacey D, Stathopoulou MG, Tanaka T, Wannamethee SG, Whincup P, Rotter JI, Dehghan A, Boerwinkle E, Psaty BM, Snieder H, Alizadeh BZ | 2021-04-27 | Human molecular genetics | |
| Association of White Matter Hyperintensity Markers on MRI and Long-term Risk of Mortality and Ischemic Stroke: The SMART-MR Study. | Ghaznawi R, Geerlings MI, Jaarsma-Coes M, Hendrikse J, de Bresser J | 2021-04-27 | Neurology | |
| Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes. | Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X, Wojczynski MK, Biggs ML, van der Spek A, Atzmon G, Ware EB, Sarnowski C, Smith AV, Seppälä I, Cordell HJ, Dose J, Amin N, Arnold AM, Ayers KL, Barzilai N, Becker EJ, Beekman M, Blanché H, Christensen K, Christiansen L, Collerton JC, Cubaynes S, Cummings SR, Davies K, Debrabant B, Deleuze JF, Duncan R, Faul JD, Franceschi C, Galan P, Gudnason V, Harris TB, Huisman M, Hurme MA, Jagger C, Jansen I, Jylhä M, Kähönen M, Karasik D, Kardia SLR, Kingston A, Kirkwood TBL, Launer LJ, Lehtimäki T, Lieb W, Lyytikäinen LP, Martin-Ruiz C, Min J, Nebel A, Newman AB, Nie C, Nohr EA, Orwoll ES, Perls TT, Province MA, Psaty BM, Raitakari OT, Reinders MJT, Robine JM, Rotter JI, Sebastiani P, Smith J, Sørensen TIA, Taylor KD, Uitterlinden AG, van der Flier W, van der Lee SJ, van Duijn CM, van Heemst D, Vaupel JW, Weir D, Ye K, Zeng Y, Zheng W, Holstege H, Kiel DP, Lunetta KL, Slagboom PE, Murabito JM | 2021-04-23 | Nature communications | |
| Practitioners’ perceptions of acceptability of a question prompt list about palliative care for advance care planning with people living with dementia and their family caregivers: a mixed-methods evaluation study. | van der Steen JT, Heck S, Juffermans CC, Garvelink MM, Achterberg WP, Clayton J, Thompson G, Koopmans RT, van der Linden YM | 2021-04-12 | adult palliative care, dementia, geriatric medicine | BMJ open |
| A European Research Agenda for Geriatric Emergency Medicine: a modified Delphi study. | Mooijaart SP, Nickel CH, Conroy SP, Lucke JA, van Tol LS, Olthof M, Blomaard LC, Buurman BM, Dundar ZD, de Groot B, Gasperini B, Heeren P, Karamercan MA, McNamara R, Mitchell A, van Oppen JD, Martin Sanchez FJ, Schoon Y, Singler K, Spode R, Skúldóttir S, Thorrsteindottir T, van der Velde M, Wallace J | 2021-04-01 | Geriatric Emergency Medicine, Research prioritisation | European geriatric medicine |
| Outcomes of Thyroid Dysfunction in People Aged Eighty Years and Older: An Individual Patient Data Meta-Analysis of Four Prospective Studies (Towards Understanding Longitudinal International Older People Studies Consortium). | Du Puy RS, Poortvliet RKE, Mooijaart SP, den Elzen WPJ, Jagger C, Pearce SHS, Arai Y, Hirose N, Teh R, Menzies O, Rolleston A, Kerse N, Gussekloo J | 2021-04-01 | IPD-MA, function, mortality, oldest old, thyroid dysfunction | Thyroid : official journal of the American Thyroid Association |
| Mapping the multicausality of Alzheimer’s disease through group model building. | Uleman JF, Melis RJF, Quax R, van der Zee EA, Thijssen D, Dresler M, van de Rest O, van der Velpen IF, Adams HHH, Schmand B, de Kok IMCM, de Bresser J, Richard E, Verbeek M, Hoekstra AG, Rouwette EAJA, Olde Rikkert MGM | 2021-04-01 | Alzheimer’s disease, Causal loop diagram, Centrality, Complexity, Group model building, Multicausal, Systems thinking | GeroScience |
| Feasibility of a multicomponent cognitive behavioral intervention for fear of falling after hip fracture: process evaluation of the FIT-HIP intervention. | Scheffers-Barnhoorn MN, van Eijk M, Schols JMGA, van Balen R, Kempen GIJM, Achterberg WP, van Haastregt JCM | 2021-04-01 | Cognitive behavioral intervention, Fear of falling, Feasibility, Geriatric rehabilitation, Hip fracture, Process evaluation | BMC geriatrics |
| Health workers’ perspectives on informed consent for caesarean section in Southern Malawi. | Bakker W, Zethof S, Nansongole F, Kilowe K, van Roosmalen J, van den Akker T | 2021-03-29 | BMC medical ethics | |
| Correction to: DIALysis or not: Outcomes in older kidney patients with GerIatriC Assessment (DIALOGICA): rationale and design. | van Oevelen M, Abrahams AC, Bos WJW, Emmelot-Vonk MH, Mooijaart SP, van Diepen M, van Jaarsveld BC, van Eck van der Sluijs A, Voorend CGN, van Buren M | 2021-03-29 | BMC nephrology | |
| Experiences with and attitudes towards geriatric screening among older emergency department patients: a qualitative study. | Blomaard LC, Olthof M, Meuleman Y, de Groot B, Gussekloo J, Mooijaart SP | 2021-03-20 | Emergency medicine, Frailty, Frailty screening, Older adults, Qualitative research | BMC geriatrics |
| Investigating the relationships between unfavourable habitual sleep and metabolomic traits: evidence from multi-cohort multivariable regression and Mendelian randomization analyses. | Bos MM, Goulding NJ, Lee MA, Hofman A, Bot M, Pool R, Vijfhuizen LS, Zhang X, Li C, Mustafa R, Neville MJ, Li-Gao R, Trompet S, Beekman M, Biermasz NR, Boomsma DI, de Boer I, Christodoulides C, Dehghan A, van Dijk KW, Ford I, Ghanbari M, Heijmans BT, Ikram MA, Jukema JW, Mook-Kanamori DO, Karpe F, Luik AI, Lumey LH, van den Maagdenberg AMJM, Mooijaart SP, de Mutsert R, Penninx BWJH, Rensen PCN, Richmond RC, Rosendaal FR, Sattar N, Schoevers RA, Slagboom PE, Terwindt GM, Thesing CS, Wade KH, Wijsman CA, Willemsen G, Zwinderman AH, van Heemst D, Noordam R, Lawlor DA | 2021-03-18 | Epidemiology, Mendelian randomization, Metabolomics, Sleep | BMC medicine |
| Self-rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains. | Kananen L, Enroth L, Raitanen J, Jylhävä J, Bürkle A, Moreno-Villanueva M, Bernhardt J, Toussaint O, Grubeck-Loebenstein B, Malavolta M, Basso A, Piacenza F, Collino S, Gonos ES, Sikora E, Gradinaru D, Jansen EHJM, Dollé MET, Salmon M, Stuetz W, Weber D, Grune T, Breusing N, Simm A, Capri M, Franceschi C, Slagboom PE, Talbot DCS, Libert C, Koskinen S, Bruunsgaard H, Hansen ÅM, Lund R, Hurme M, Jylhä M | 2021-03-17 | Scientific reports | |
| Correction for both common and rare cell types in blood is important to identify genes that correlate with age. | Pellegrino-Coppola D, Claringbould A, Stutvoet M, Boomsma DI, Ikram MA, Slagboom PE, Westra HJ, Franke L | 2021-03-15 | Aging, Cell counts correction, Gene expression, Platelet activity, Whole blood | BMC genomics |
| Geriatric screening, fall characteristics and 3- and 12 months adverse outcomes in older patients visiting the emergency department with a fall. | Blomaard LC, Mooijaart SP, van Meer LJ, Leander J, Lucke JA, de Gelder J, Anten S, Gussekloo J, de Groot B | 2021-03-04 | Aged, Falls, Frailty, Geriatric emergency medicine, Older adults | Scandinavian journal of trauma, resuscitation and emergency medicine |
| Families in comparison: An individual-level comparison of life-course and family reconstructions between population and vital event registers. | van den Berg N, van Dijk IK, Mourits RJ, Slagboom PE, Janssens AAPO, Mandemakers K | 2021-03-01 | civil registers, databases, demographic methods, family history, family reconstitutions, family reconstruction, historical demography, life course, microdata, population registers | Population studies |
| Common Genetic Variation in MC4R Does Not Affect Atherosclerotic Plaque Phenotypes and Cardiovascular Disease Outcomes. | Blauw LL, Noordam R, van der Laan SW, Trompet S, Kooijman S, van Heemst D, Jukema JW, van Setten J, de Borst GJ, Tybjærg-Hansen A, Pasterkamp G, Berbée JFP, Rensen PCN | 2021-03-01 | BMI, MC4R, atherosclerosis, cardiovascular disease, genetics | Journal of clinical medicine |
| Association between Clinical Frailty Scale score and hospital mortality in adult patients with COVID-19 (COMET): an international, multicentre, retrospective, observational cohort study. | Sablerolles RSG, Lafeber M, van Kempen JAL, van de Loo BPA, Boersma E, Rietdijk WJR, Polinder-Bos HA, Mooijaart SP, van der Kuy H, Versmissen J, Faes MC | 2021-03-01 | The lancet. Healthy longevity | |
| Improving the care for older emergency department patients: the Acutely Presenting Older Patient study. | Mooijaart SP | 2021-03-01 | Zeitschrift fur Gerontologie und Geriatrie | |
| Implementation of the acutely presenting older patient (APOP) screening program in routine emergency department care : A before-after study. | Blomaard LC, de Groot B, Lucke JA, de Gelder J, Booijen AM, Gussekloo J, Mooijaart SP | 2021-03-01 | Frail elderly, Geriatric assessment, Geriatric emergency medicine, Implementation science, Quality improvement | Zeitschrift fur Gerontologie und Geriatrie |
| The Association Between Pain Perception and Care Dependency in Older Nursing Home Residents: A Prospective Cohort Study. | Steenbeek ED, Ramspek CL, van Diepen M, Dekker FW, Achterberg WP | 2021-03-01 | Pain, care dependency, cognitive performance, nursing homes, older | Journal of the American Medical Directors Association |
| Perceptions of Factors Leading to Teenage Pregnancy in Lindi Region, Tanzania: A Grounded Theory Study. | Te Lindert L, van der Deijl M, Elirehema A, van Elteren-Jansen M, Chitanda R, van den Akker T | 2021-02-22 | The American journal of tropical medicine and hygiene | |
| The effect of a telephone follow-up call for older patients, discharged home from the emergency department on health-related outcomes: a systematic review of controlled studies. | van Loon-van Gaalen M, van Winsen B, van der Linden MC, Gussekloo J, van der Mast RC | 2021-02-18 | Emergency department, Geriatric, Older patients, Postdischarge follow-up, Telephone | International journal of emergency medicine |
| Family Planning Uptake in Kagera and Mara Regions in Tanzania: A Cross-Sectional Community Survey. | Massenga J, Noronha R, Awadhi B, Bishanga D, Safari O, Njonge L, Kim YM, Roosmalen JV, van den Akker T | 2021-02-09 | antenatal care, childbirth, community health worker, facility health care worker, family planning, male partner | International journal of environmental research and public health |
| [From healthy individuals to healthy populations]. | van de Vijver PL, van Bodegom D | 2021-02-04 | Nederlands tijdschrift voor geneeskunde | |
| Associations of Cytomegalovirus Infection With All-Cause and Cardiovascular Mortality in Multiple Observational Cohort Studies of Older Adults. | Chen S, Pawelec G, Trompet S, Goldeck D, Mortensen LH, Slagboom PE, Christensen K, Gussekloo J, Kearney P, Buckley BM, Ford I, Jukema JW, Westendorp RGJ, Maier AB | 2021-02-03 | Herpesviridae, aged, cardiovascular, cytomegalovirus, immunoglobulin G, mortality, seroepidemiologic studies | The Journal of infectious diseases |
| Detailed immune monitoring of a pregnant woman with critical Covid-19. | du Fossé NA, Bronsgeest K, Arbous MS, Zlei M, Myeni SK, Kikkert M, van Dongen J, Staal F, van der Hoorn M, van den Akker T | 2021-02-01 | Covid-19, Flow cytometry, Immune monitoring, Pregnancy | Journal of reproductive immunology |
| Cost-utility and cost-effectiveness analysis of a clinical medication review focused on personal goals in older persons with polypharmacy compared to usual care: Economic evaluation of the DREAMeR study. | Verdoorn S, van de Pol J, Hövels AM, Kwint HF, Blom JW, Gussekloo J, Bouvy ML | 2021-02-01 | clinical medication review, cost-effectiveness, older persons, polypharmacy, primary care, randomised controlled trial | British journal of clinical pharmacology |
| Effect of Levothyroxine Therapy on the Development of Depressive Symptoms in Older Adults With Subclinical Hypothyroidism: An Ancillary Study of a Randomized Clinical Trial. | Wildisen L, Feller M, Del Giovane C, Moutzouri E, Du Puy RS, Mooijaart SP, Collet TH, Poortvliet RKE, Kearney P, Quinn TJ, Klöppel S, Bauer DC, Peeters RP, Westendorp R, Aujesky D, Gussekloo J, Rodondi N | 2021-02-01 | JAMA network open | |
| Letter to Kawijara et al.: Letter in response to “Effects of Caregiver Dementia Training in Caregiver-Patient Dyads”. | Birkenhäger-Gillesse EG, Achterberg WP, Zuidema SU | 2021-02-01 | caregiver, dementia, psychological intervention, training | International journal of geriatric psychiatry |
| Frailty is associated with in-hospital mortality in older hospitalised COVID-19 patients in the Netherlands: the COVID-OLD study | Blomaard LC, van der Linden CMJ, van der Bol JM, Jansen SWM, Polinder-Bos HA, Willems HC, Festen J, Barten DG, Borgers AJ, Bos JC, van den Bos F, de Brouwer EJM, van Deudekom FJA, van Dijk SC, Emmelot-Vonk MH, Geels RES, van de Glind EMM, de Groot B, Hempenius L, Kamper AM, Kampschreur LM, de Koning MMM, Labots G, Looman R, Lucke JA, Maas HAAM, Mattace-Raso FUS, el Moussaoui R, van Munster BC, van Nieuwkoop C, Oosterwijk L(LE, Regtuijt M(M, Robben SHM, Ruiter R, Salarbaks AM, Schouten HJ, Smit OM, Smits RAL, Spies PE, Vreeswijk R, de Vries OJ, Wijngaarden MA, Wyers CE, Mooijaart SP | 2021-01-30 | Age and Ageing | |
| DIALysis or not: Outcomes in older kidney patients with GerIatriC Assessment (DIALOGICA): rationale and design. | van Oevelen M, Abrahams AC, Bos WJW, Emmelot-Vonk MH, Mooijaart SP, van Diepen M, van Jaarsveld BC, van Eck van der Sluijs A, Voorend CGN, van Buren M | 2021-01-23 | Costs and cost analysis, Dialysis, Frailty, geriatric assessment, Kidney failure, chronic, Mortality, Quality of life | BMC nephrology |
| Understanding the perspectives and values of midwives, obstetricians and obstetric registrars regarding episiotomy: qualitative interview study. | Seijmonsbergen-Schermers A, Thompson S, Feijen-de Jong E, Smit M, Prins M, van den Akker T, de Jonge A | 2021-01-13 | obstetrics, perinatology, qualitative research | BMJ open |
| Anaemia and physical and mental health in the very old: An individual participant data meta-analysis of four longitudinal studies of ageing. | Palapar L, Kerse N, Rolleston A, den Elzen WPJ, Gussekloo J, Blom JW, Robinson L, Martin-Ruiz C, Duncan R, Arai Y, Takayama M, Teh R | 2021-01-08 | 80 and over, Activities of daily living, Aged, Anaemia, Cognitive function, Depression | Age and ageing |
| Design and rationale of a routine clinical care pathway and prospective cohort study in older patients needing intensive treatment. | van Holstein Y, van Deudekom FJ, Trompet S, Postmus I, Uit den Boogaard A, van der Elst MJT, de Glas NA, van Heemst D, Labots G, Altena M, Slingerland M, Liefers GJ, van den Bos F, van der Bol JM, Blauw GJ, Portielje JEA, Mooijaart SP | 2021-01-07 | Aortic valve replacement, Colon cancer, Comprehensive geriatric assessment, Frailty, Geriatric oncology, Head and neck cancer, Oesophageal cancer, Older patients, Study protocol | BMC geriatrics |
| General practitioners’ deprescribing decisions in older adults with polypharmacy: a case vignette study in 31 countries. | Jungo KT, Mantelli S, Rozsnyai Z, Missiou A, Kitanovska BG, Weltermann B, Mallen C, Collins C, Bonfim D, Kurpas D, Petrazzuoli F, Dumitra G, Thulesius H, Lingner H, Johansen KL, Wallis K, Hoffmann K, Peremans L, Pilv L, Šter MP, Bleckwenn M, Sattler M, van der Ploeg M, Torzsa P, Kánská PB, Vinker S, Assenova R, Bravo RG, Viegas RPA, Tsopra R, Pestic SK, Gintere S, Koskela TH, Lazic V, Tkachenko V, Reeve E, Luymes C, Poortvliet RKE, Rodondi N, Gussekloo J, Streit S | 2021-01-07 | Deprescribing, Multimorbidity, Old age, Polypharmacy, Primary health care | BMC geriatrics |
| Perspectives and experiences of patients and healthcare professionals with geriatric assessment in chronic kidney disease: a qualitative study. | Voorend CGN, Berkhout-Byrne NC, Meuleman Y, Mooijaart SP, Bos WJW, van Buren M | 2021-01-06 | Chronic kidney failure, Decision making, shared, ESRD, Focus groups, Frail older adults, Geriatric assessment, Qualitative research, Quality of life | BMC nephrology |
| Diet-Derived Circulating Antioxidants and Risk of Coronary Heart Disease: A Mendelian Randomization Study. | Luo J, le Cessie S, van Heemst D, Noordam R | 2021-01-05 | Mendelian randomization, antioxidant, coronary heart disease | Journal of the American College of Cardiology |
| Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. | Munn-Chernoff MA, Johnson EC, Chou YL, Coleman JRI, Thornton LM, Walters RK, Yilmaz Z, Baker JH, Hübel C, Gordon S, Medland SE, Watson HJ, Gaspar HA, Bryois J, Hinney A, Leppä VM, Mattheisen M, Ripke S, Yao S, Giusti-Rodríguez P, Hanscombe KB, Adan RAH, Alfredsson L, Ando T, Andreassen OA, Berrettini WH, Boehm I, Boni C, Boraska Perica V, Buehren K, Burghardt R, Cassina M, Cichon S, Clementi M, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, Davis OSP, de Zwaan M, Dedoussis G, Degortes D, DeSocio JE, Dick DM, Dikeos D, Dina C, Dmitrzak-Weglarz M, Docampo E, Duncan LE, Egberts K, Ehrlich S, Escaramís G, Esko T, Estivill X, Farmer A, Favaro A, Fernández-Aranda F, Fichter MM, Fischer K, Föcker M, Foretova L, Forstner AJ, Forzan M, Franklin CS, Gallinger S, Giegling I, Giuranna J, Gonidakis F, Gorwood P, Gratacos Mayora M, Guillaume S, Guo Y, Hakonarson H, Hatzikotoulas K, Hauser J, Hebebrand J, Helder SG, Herms S, Herpertz-Dahlmann B, Herzog W, Huckins LM, Hudson JI, Imgart H, Inoko H, Janout V, Jiménez-Murcia S, Julià A, Kalsi G, Kaminská D, Karhunen L, Karwautz A, Kas MJH, Kennedy JL, Keski-Rahkonen A, Kiezebrink K, Kim YR, Klump KL, Knudsen GPS, La Via MC, Le Hellard S, Levitan RD, Li D, Lilenfeld L, Lin BD, Lissowska J, Luykx J, Magistretti PJ, Maj M, Mannik K, Marsal S, Marshall CR, Mattingsdal M, McDevitt S, McGuffin P, Metspalu A, Meulenbelt I, Micali N, Mitchell K, Monteleone AM, Monteleone P, Nacmias B, Navratilova M, Ntalla I, O'Toole JK, Ophoff RA, Padyukov L, Palotie A, Pantel J, Papezova H, Pinto D, Rabionet R, Raevuori A, Ramoz N, Reichborn-Kjennerud T, Ricca V, Ripatti S, Ritschel F, Roberts M, Rotondo A, Rujescu D, Rybakowski F, Santonastaso P, Scherag A, Scherer SW, Schmidt U, Schork NJ, Schosser A, Seitz J, Slachtova L, Slagboom PE, Slof-Op't Landt MCT, Slopien A, Sorbi S, Świątkowska B, Szatkiewicz JP, Tachmazidou I, Tenconi E, Tortorella A, Tozzi F, Treasure J, Tsitsika A, Tyszkiewicz-Nwafor M, Tziouvas K, van Elburg AA, van Furth EF, Wagner G, Walton E, Widen E, Zeggini E, Zerwas S, Zipfel S, Bergen AW, Boden JM, Brandt H, Crawford S, Halmi KA, Horwood LJ, Johnson C, Kaplan AS, Kaye WH, Mitchell J, Olsen CM, Pearson JF, Pedersen NL, Strober M, Werge T, Whiteman DC, Woodside DB, Grove J, Henders AK, Larsen JT, Parker R, Petersen LV, Jordan J, Kennedy MA, Birgegård A, Lichtenstein P, Norring C, Landén M, Mortensen PB, Polimanti R, McClintick JN, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Degenhardt F, Docherty AR, Edwards AC, Foo JC, Fox L, Frank J, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Hodgkinson C, Hoffmann P, Hottenga JJ, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Peterson RE, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG, Zhou H, Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Frye MA, Gäebel W, Hayward C, Ising M, Keyes M, Kiefer F, Koller G, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Männistö S, Müller-Myhsok B, Murray AD, Nurnberger JI, Preuss U, Räikkönen K, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt SH, Wodarz N, Zill P, Adkins DE, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Costello EJ, de Wit H, Diazgranados N, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Hesselbrock V, Hewitt JK, Hopfer CJ, Iacono WG, Johnson EO, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lind PA, McGue M, MacKillop J, Madden PAF, Maes HH, Magnusson PKE, Nelson EC, Nöthen MM, Palmer AA, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose RJ, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Wade TD, Heath AC, Montgomery GW, Martin NG, Sullivan PF, Kaprio J, Breen G, Gelernter J, Edenberg HJ, Bulik CM, Agrawal A | 2021-01-01 | eating disorders, genetic correlation, substance use | Addiction biology |
| Microbiome in Blood Samples From the General Population Recruited in the MARK-AGE Project: A Pilot Study. | D'Aquila P, Giacconi R, Malavolta M, Piacenza F, Bürkle A, Villanueva MM, Dollé MET, Jansen E, Grune T, Gonos ES, Franceschi C, Capri M, Grubeck-Loebenstein B, Sikora E, Toussaint O, Debacq-Chainiaux F, Hervonen A, Hurme M, Slagboom PE, Schön C, Bernhardt J, Breusing N, Passarino G, Provinciali M, Bellizzi D | 2021-01-01 | 16S rRNA gene, aging, blood microbiome, free fatty acids, geographic origin, glucose, insulin, leukocytes | Frontiers in microbiology |
| Variants of FOXO3 and RPA3 genes affecting IGF-1 levels alter the risk of development of primary osteoarthritis. | Pelsma ICM, Claessen KMJA, Slagboom PE, van Heemst D, Pereira AM, Kroon HM, Ramos YFM, Kloppenburg M, Biermasz NR, Meulenbelt IM | 2021-01-01 | European journal of endocrinology | |
| Within-Person Variation in Serum Thyrotropin Concentrations: Main Sources, Potential Underlying Biological Mechanisms, and Clinical Implications. | van der Spoel E, Roelfsema F, van Heemst D | 2021-01-01 | ageing, biological variation, circadian rhythm, seasonality, thyroid-stimulating hormone, thyrotropin, within-person variation | Frontiers in endocrinology |
| Determining the frequency of thyroid parameter measurements following rhTSH administration in a healthy, older population. | Zutinic A, Blauw GJ, van Heemst D | 2021-01-01 | Blood sampling, Geriatrics, Longevity, Thyroid, rhTSH | MethodsX |
| Images in cytology: Fine needle aspiration cytology of BRAFV600E positive anaplastic thyroid carcinoma. | Xing MH, van den Akker T, Gonzalez-Velazquez C, Urken ML, Chen H | 2021-01-01 | Diagnostic cytopathology | |
| Transfusion reactions associated with COVID-19 convalescent plasma therapy for SARS-CoV-2. | Nguyen FT, van den Akker T, Lally K, Lam H, Lenskaya V, Liu STH, Bouvier NM, Aberg JA, Rodriguez D, Krammer F, Strauss D, Shaz BH, Rudon L, Galdon P, Jhang JS, Arinsburg SA, Baine I | 2021-01-01 | FFP transfusion, immunology (other than RBC serology), transfusion practices (adult) | Transfusion |
| Learning from changes concurrent with implementing a complex and dynamic intervention to improve urban maternal and perinatal health in Dar es Salaam, Tanzania, 2011-2019. | Sequeira Dmello B, Sellah Z, Magembe G, Housseine N, Maaløe N, van den Akker T, Meyrowitsch DW, Mushi T, Masweko M, Jidayi D, van Roosmalen J, Kidanto HL | 2021-01-01 | health services research, intervention study, maternal health, public health | BMJ global health |
| A total blood volume or more transfused during pregnancy or after childbirth: Individual patient data from six international population-based observational studies. | McCall SJ, Henriquez D, Edwards HM, van den Akker T, Bloemenkamp KWM, van der Bom J, Bonnet MP, Deneux-Tharaux C, Donati S, Gillissen A, Kurinczuk JJ, Li Z, Maraschini A, Seco A, Sullivan E, Stanworth S, Knight M | 2021-01-01 | PloS one | |
| Quality of Maternal Death Documentation in Afghanistan: A Retrospective Health Facility Record Review. | Maruf F, Tappis H, Stekelenburg J, van den Akker T | 2021-01-01 | Afghanistan, maternal health, maternal mortality, medical records, pregnancy related death, quality of documentation | Frontiers in global women's health |
| Interplay of circulating leptin and obesity in cognition and cerebral volumes in older adults. | Zonneveld MH, Noordam R, van der Grond J, van Heemst D, Mooijaart SP, Sabayan B, Jukema JW, Trompet S | 2021-01-01 | BMI, Cardiovascular disease, Cerebral volumes, Circulating leptin, Cognitive dysfunction, Older adults | Peptides |
| Correction: Statin Use and Self-Reported Hindering Muscle Complaints in Older Persons: A Population Based Study. | van der Ploeg MA, Poortvliet RKE, van Blijswijk SCE, den Elzen WPJ, van Peet PG, Ruijter W, Blom JW, Gussekloo J | 2021-01-01 | PloS one | |
| Levothyroxine Treatment and Cardiovascular Outcomes in Older People With Subclinical Hypothyroidism: Pooled Individual Results of Two Randomised Controlled Trials. | Zijlstra LE, Jukema JW, Westendorp RGJ, Du Puy RS, Poortvliet RKE, Kearney PM, O'Keeffe L, Dekkers OM, Blum MR, Rodondi N, Collet TH, Quinn TJ, Sattar N, Stott DJ, Trompet S, den Elzen WPJ, Gussekloo J, Mooijaart SP | 2021-01-01 | cardiovascular disease, levothyroxine, older adults, randomised controlled trial, subclinical hypothyroidism | Frontiers in endocrinology |
| Evaluation of High Cholesterol and Risk of Dementia and Cognitive Decline in Older Adults Using Individual Patient Meta-Analysis. | Peters R, Xu Y, Antikainen R, Beckett N, Gussekloo J, Jagger C, Jukema JW, Keinanen-Kiukaanniemi S, Rydén L, Skoog I, Staessen JA, Thijs L, Trompet S, Tully PJ, Tzourio C, Anstey KJ | 2021-01-01 | Ageing, Cholesterol, Cognitive decline, Dementia | Dementia and geriatric cognitive disorders |
| Hypertensive Exposure Markers by MRI in Relation to Cerebral Small Vessel Disease and Cognitive Impairment. | Amier RP, Marcks N, Hooghiemstra AM, Nijveldt R, van Buchem MA, de Roos A, Biessels GJ, Kappelle LJ, van Oostenbrugge RJ, van der Geest RJ, Bots ML, Greving JP, Niessen WJ, van Osch MJP, de Bresser J, van de Ven PM, van der Flier WM, Brunner-La Rocca HP, van Rossum AC | 2021-01-01 | cognition, left ventricular mass, left ventricular mass-to-volume ratio, pulse wave velocity, vascular brain injury | JACC. Cardiovascular imaging |
| Preoperative brain MRI features and occurrence of postoperative delirium. | Kant IMJ, de Bresser J, van Montfort SJT, Mutsaerts HJMM, Witkamp TD, Buijsrogge M, Spies C, Hendrikse J, Slooter AJC | 2021-01-01 | Cortical infarcts, Delirium, MRI markers, White matter hyperintensities | Journal of psychosomatic research |
| The association between intraoperative hyperglycemia and cerebrovascular markers. | Knaak C, Kant IM, Lammers-Lietz F, Spies C, Witkamp TD, Winterer G, Lachmann G, de Bresser J | 2021-01-01 | Intraoperative hyperglycemia, Neuroimaging MRI, cerebral small vessel disease, perfusion, vascular lesions. | International journal of medical sciences |
| Intracranial Atherosclerotic Burden and Cerebral Parenchymal Changes at 7T MRI in Patients With Transient Ischemic Attack or Ischemic Stroke. | Lindenholz A, de Bresser J, van der Kolk AG, van der Worp HB, Witkamp TD, Hendrikse J, van der Schaaf IC | 2021-01-01 | intracranial arteries, intracranial atherosclerosis, intracranial vessel wall MR imaging, large vessel disease, small vessel disease, white matter hyperintensity | Frontiers in neurology |
| Sex and Cardiovascular Function in Relation to Vascular Brain Injury in Patients with Cognitive Complaints. | Kuipers S, Biessels GJ, Greving JP, Amier RP, de Bresser J, Bron EE, van der Flier WM, van der Geest RJ, Hooghiemstra AM, van Oostenbrugge RJ, van Osch MJP, Kappelle LJ, Exalto LG | 2021-01-01 | Cardiovascular function, cerebrovascular disorders, cognitive dysfunction, female, male, sex, vascular brain injury | Journal of Alzheimer's disease : JAD |
| Blood pressure, antihypertensive medication and neuropsychiatric symptoms in older people with dementia: The COSMOS study. | de Jong-Schmit BEM, Poortvliet RKE, Böhringer S, Bogaerts JMK, Achterberg WP, Husebo BS | 2021-01-01 | antihypertensive medication, blood pressure, dementia, neuropsychiatric symptoms | International journal of geriatric psychiatry |
| Caffeine Consumption and Behavioral Symptoms in Nursing Home Residents: A Cross-Sectional Analysis. | Kromhout MA, Rius Ottenheim N, Putter H, Numans ME, Achterberg WP | 2021-01-01 | Behavioral symptoms, caffeine, dementia, nursing home | The journal of nutrition, health & aging |
| Physicians’ perceived barriers and proposed solutions for high-quality palliative care in dementia in the Netherlands: Qualitative analysis of survey data. | Bavelaar L, van der Steen HTA, de Jong H, Carter G, Brazil K, Achterberg WP, van der Steen JT | 2021-01-01 | Dementia, geriatrics, nursing homes, palliative care | The journal of nursing home research sciences |
| Caregiver dementia training in caregiver-patient dyads: Process evaluation of a randomized controlled study. | Birkenhäger-Gillesse EG, Achterberg WP, Janus SIM, Zuidema SU | 2021-01-01 | caregiver, dementia, psychosocial intervention, training | International journal of geriatric psychiatry |
| Are Chronic Pain Patients with Dementia Being Undermedicated? | Achterberg WP, Erdal A, Husebo BS, Kunz M, Lautenbacher S | 2021-01-01 | analgesic treatment, assessment, dementia, pain | Journal of pain research |
| Pan-European Study on Functional and Medical Recovery and Geriatric Rehabilitation Services of Post-COVID-19 Patients: Protocol of the EU-COGER Study. | Grund S, Caljouw MAA, Haaksma ML, Gordon AL, van Balen R, Bauer JM, Schols JMGA, Achterberg WP | 2021-01-01 | ADL functioning, COVID-19, geriatric rehabilitation, older persons, post-acute | The journal of nutrition, health & aging |
| Effects of Caregiver Dementia Training in Caregiver-Patient Dyads on Psychotropic Drug Prescription: A Randomized Controlled Study. | Birkenhäger-Gillesse EG, Janus SIM, Achterberg WP, Zuidema SU | 2021-01-01 | caregiver, dementia, psychosocial intervention, psychotropic drugs, training | Clinical interventions in aging |
| Does paracetamol improve quality of life, discomfort, pain and neuropsychiatric symptoms in persons with advanced dementia living in long-term care facilities? A randomised double-blind placebo-controlled crossover (Q-PID) trial. | van Dam PH, Achterberg WP, Husebo BS, Caljouw MAA | 2020-12-21 | Dementia, Long-term care facility, Paracetamol, QUALIDEM, Quality of life | BMC medicine |
| Association of common genetic variants with brain microbleeds: A genome-wide association study. | Knol MJ, Lu D, Traylor M, Adams HHH, Romero JRJ, Smith AV, Fornage M, Hofer E, Liu J, Hostettler IC, Luciano M, Trompet S, Giese AK, Hilal S, van den Akker EB, Vojinovic D, Li S, Sigurdsson S, van der Lee SJ, Jack CR, Wilson D, Yilmaz P, Satizabal CL, Liewald DCM, van der Grond J, Chen C, Saba Y, van der Lugt A, Bastin ME, Windham BG, Cheng CY, Pirpamer L, Kantarci K, Himali JJ, Yang Q, Morris Z, Beiser AS, Tozer DJ, Vernooij MW, Amin N, Beekman M, Koh JY, Stott DJ, Houlden H, Schmidt R, Gottesman RF, MacKinnon AD, DeCarli C, Gudnason V, Deary IJ, van Duijn CM, Slagboom PE, Wong TY, Rost NS, Jukema JW, Mosley TH, Werring DJ, Schmidt H, Wardlaw JM, Ikram MA, Seshadri S, Launer LJ, Markus HS | 2020-12-15 | Neurology | |
| Associations between Lifestyle Factors and Vitamin E Metabolites in the General Population. | Martens LG, Luo J, Meulmeester FL, Ashrafi N, van Eekelen EW, de Mutsert R, Mook-Kanamori DO, Rosendaal FR, van Dijk KW, Mills K, Noordam R, van Heemst D | 2020-12-15 | alcohol, antioxidants, diet, lifestyle, physical activity, sleep, smoking, vitamin E | Antioxidants (Basel, Switzerland) |
| Introduction of Criterion-Based Audit of Postpartum Hemorrhage in a University Hospital in Eastern Ethiopia: Implementation and Considerations. | Tura AK, Aboul-Ela Y, Fage SG, Ahmed SS, Scherjon S, van Roosmalen J, Stekelenburg J, Zwart J, van den Akker T | 2020-12-11 | Ethiopia, criterion-based audit, postpartum hemorrhage | International journal of environmental research and public health |
| Perspectives of health workers on the referral of women with obstetric complications: a qualitative study in rural Sierra Leone. | Proos R, Mathéron H, Vas Nunes J, Falama A, Sery Kamal P, Grobusch MP, van den Akker T | 2020-12-10 | maternal medicine, organisation of health services, public health, qualitative research | BMJ open |
| Kawasaki disease seasonality in Venezuela supports an arbovirus infection trigger. | Paniz-Mondolfi AE, van den Akker T, Márquez-Colmenarez MC, Delgado-Noguera LA, Valderrama O, Sordillo EM | 2020-12-01 | DENV, Kawasaki disease, Venezuela, arboviruses, seasonality | Journal of medical virology |
| Self-organizing peer coach groups to increase daily physical activity in community dwelling older adults. | van de Vijver P, Schalkwijk F, Numans ME, Slaets JPJ, van Bodegom D | 2020-12-01 | Feasibility, Implementation, Older adults, Peer coaching, Physical activity, Replicability | Preventive medicine reports |
| Prediction admission in the older population in the Emergency Department: the CLEARED tool. | Brink A, Alsma J, Brink HS, de Gelder J, Lucke JA, Mooijaart SP, Zietse R, Schuit SCE, Lingsma HF | 2020-12-01 | The Netherlands journal of medicine | |
| Measuring daily functioning in older persons using a frailty index: a cohort study based on routine primary care data. | Ravensbergen WM, Blom JW, Evers AW, Numans ME, de Waal MW, Gussekloo J | 2020-12-01 | activities of daily living, aged, electronic health records, frail older persons, general practice | The British journal of general practice : the journal of the Royal College of General Practitioners |
| Experiences with the Liverpool care pathway for the dying patient in nursing home residents: a mixed-method study to assess physicians’ and nurse practitioners’ perceptions. | Klapwijk MS, Dekker NL, Caljouw MAA, Achterberg WP, van der Steen JT | 2020-11-30 | Dementia, End-of-life care, Liverpool care pathway, Nursing home, Palliative care, Quality of care | BMC palliative care |
| Associations between outdoor temperature and bright sunlight with metabolites in two population-based European cohorts. | Eveleens Maarse BC, Loh NY, Karpe F, Rosendaal FR, van Heemst D, Mook-Kanamori DO, Willems van Dijk K, Rensen PCN, Kooijman S, Christodoulides C, Noordam R | 2020-11-27 | Cohort studies, Epidemiology, Lipoproteins, Metabolomics, Outdoor bright sunlight, Outdoor temperature | Nutrition, metabolism, and cardiovascular diseases : NMCD |
| A Workflow for Missing Values Imputation of Untargeted Metabolomics Data. | Faquih T, van Smeden M, Luo J, le Cessie S, Kastenmüller G, Krumsiek J, Noordam R, van Heemst D, Rosendaal FR, van Hylckama Vlieg A, Willems van Dijk K, Mook-Kanamori DO | 2020-11-26 | imputation, k-nearest neighbors, metabolon, multiple imputation using chained equations, simulation, untargeted metabolomics, workflow | Metabolites |
| Which moral barriers and facilitators do physicians encounter in advance care planning conversations about the end of life of persons with dementia? A meta-review of systematic reviews and primary studies. | Keijzer-van Laarhoven AJ, Touwen DP, Tilburgs B, van Tilborg-den Boeft M, Pees C, Achterberg WP, van der Steen JT | 2020-11-12 | geriatric medicine, medical ethics, palliative care, primary care | BMJ open |
| Impact of Medical Doctors Global Health and Tropical Medicine on decision-making in caesarean section: a pre- and post-implementation study in a rural hospital in Malawi. | Bakker W, Bakker E, Huigens C, Kaunda E, Phiri T, Beltman J, van Roosmalen J, van den Akker T | 2020-11-09 | Associate clinicians, Audit, Caesarean section, MDGHTM, Unnecessary caesareans | Human resources for health |
| An individual participant data analysis of prospective cohort studies on the association between subclinical thyroid dysfunction and depressive symptoms. | Wildisen L, Del Giovane C, Moutzouri E, Beglinger S, Syrogiannouli L, Collet TH, Cappola AR, Åsvold BO, Bakker SJL, Yeap BB, Almeida OP, Ceresini G, Dullaart RPF, Ferrucci L, Grabe H, Jukema JW, Nauck M, Trompet S, Völzke H, Westendorp R, Gussekloo J, Klöppel S, Aujesky D, Bauer D, Peeters R, Feller M, Rodondi N | 2020-11-05 | Scientific reports | |
| Effects of caregiver dementia training in caregiver-patient dyads: A randomized controlled study. | Birkenhäger-Gillesse EG, Achterberg WP, Janus SIM, Kollen BJ, Zuidema SU | 2020-11-01 | caregiver, dementia, psychosocial intervention, training | International journal of geriatric psychiatry |
| What do older adults with multimorbidity and polypharmacy think about deprescribing? The LESS study – a primary care-based survey. | Rozsnyai Z, Jungo KT, Reeve E, Poortvliet RKE, Rodondi N, Gussekloo J, Streit S | 2020-10-31 | Deprescribing, General practice, Multimorbidity, Older adults, Patient attitudes, Polypharmacy | BMC geriatrics |
| Feasibility and acceptability of the ‘Acutely Presenting Older Patient’ screener in routine emergency department care. | Blomaard LC, Mooijaart SP, Bolt S, Lucke JA, de Gelder J, Booijen AM, Gussekloo J, de Groot B | 2020-10-23 | emergency department, feasibility studies, geriatric assessment, geriatric emergency medicine, implementation science, older people | Age and ageing |
| Older individuals’ views on their personal screening results for complex health problems: a qualitative study. | van Blijswijk SCE, van Tol LS, Blom JW, den Elzen WPJ, Gussekloo J | 2020-10-19 | Community-dwelling older persons, Older individuals’ views, Personal goals, Screening questionnaire, Self-management | BMC family practice |
| Circulating Thyroid Hormone Profile in Response to a Triiodothyronine Challenge in Familial Longevity. | Zutinic A, Blauw GJ, Pijl H, Ballieux BE, Westendorp RGJ, Roelfsema F, van Heemst D | 2020-10-01 | 3, 5, 3′-triiodothyronine, TSH, longevity, negative feedback, thyroid | Journal of the Endocrine Society |
| Epidemiological analysis of peripartum hysterectomy across nine European countries. | Kallianidis AF, Maraschini A, Danis J, Colmorn LB, Deneux-Tharaux C, Donati S, Gissler M, Jakobsson M, Knight M, Kristufkova A, Lindqvist PG, Vandenberghe G, Van Den Akker T | 2020-10-01 | cesarean section, maternal morbidity, mode of birth, obstetric hemorrhage, peripartum hysterectomy | Acta obstetricia et gynecologica Scandinavica |
| Impact of COVID-19 on maternal and child health. | Dmello BS, Housseine N, van den Akker T, van Roosmalen J, Maaløe N | 2020-10-01 | The Lancet. Global health | |
| Metabolic Age Based on the BBMRI-NL 1H-NMR Metabolomics Repository as Biomarker of Age-related Disease. | van den Akker EB, Trompet S, Barkey Wolf JJH, Beekman M, Suchiman HED, Deelen J, Asselbergs FW, Boersma E, Cats D, Elders PM, Geleijnse JM, Ikram MA, Kloppenburg M, Mei H, Meulenbelt I, Mooijaart SP, Nelissen RGHH, Netea MG, Penninx BWJH, Slofstra M, Stehouwer CDA, Swertz MA, Teunissen CE, Terwindt GM, 't Hart LM, van den Maagdenberg AMJM, van der Harst P, van der Horst ICC, van der Kallen CJH, van Greevenbroek MMJ, van Spil WE, Wijmenga C, Zhernakova A, Zwinderman AH, Sattar N, Jukema JW, van Duijn CM, Boomsma DI, Reinders MJT, Slagboom PE | 2020-10-01 | aging, cardiovascular disease, data science, metabolomics | Circulation. Genomic and precision medicine |
| ExploreASL: An image processing pipeline for multi-center ASL perfusion MRI studies. | Mutsaerts HJMM, Petr J, Groot P, Vandemaele P, Ingala S, Robertson AD, Václavů L, Groote I, Kuijf H, Zelaya F, O'Daly O, Hilal S, Wink AM, Kant I, Caan MWA, Morgan C, de Bresser J, Lysvik E, Schrantee A, Bjørnebekk A, Clement P, Shirzadi Z, Kuijer JPA, Wottschel V, Anazodo UC, Pajkrt D, Richard E, Bokkers RPH, Reneman L, Masellis M, Günther M, MacIntosh BJ, Achten E, Chappell MA, van Osch MJP, Golay X, Thomas DL, De Vita E, Bjørnerud A, Nederveen A, Hendrikse J, Asllani I, Barkhof F | 2020-10-01 | Arterial spin labeling, Cerebral perfusion, Image processing, Multi-center, Quality control | NeuroImage |
| Myelin water imaging from multi-echo T2 MR relaxometry data using a joint sparsity constraint. | Nagtegaal M, Koken P, Amthor T, de Bresser J, Mädler B, Vos F, Doneva M | 2020-10-01 | Demyelination, Joint sparsity constraint, Myelin water fraction, T(2) relaxometry | NeuroImage |
| Crying out in pain-A systematic review into the validity of vocalization as an indicator for pain. | Helmer LML, Weijenberg RAF, de Vries R, Achterberg WP, Lautenbacher S, Sampson EL, Lobbezoo F | 2020-10-01 | European journal of pain (London, England) | |
| Independent factors associated with long-term functional outcomes in patients with a proximal femoral fracture: A systematic review. | van der Sijp MPL, van Eijk M, Tong WH, Niggebrugge AHP, Schoones JW, Blauw GJ, Achterberg WP | 2020-10-01 | Function, Functional outcome, Hip fracture, Long-term, Prognostic factors, Proximal femoral fracture | Experimental gerontology |
| Metabolic Age Based on the BBMRI-NL 1H-NMR Metabolomics Repository as Biomarker of Age-related Disease | van den Akker EB, Trompet S, Barkey Wolf JJ, Beekman M, Suchiman HED, Deelen J, Asselbergs FW, Boersma E, Cats D, Elders PM, Geleijnse JM, Ikram MA, Kloppenburg M, Mei H, Meulenbelt I, Mooijaart SP, Nelissen RG, Netea MG, Penninx BW, Slofstra M, Stehouwer CD, Swertz MA, Teunissen CE, Terwindt GM, ‘t Hart LM, van den Maagdenberg AM, van der Harst P, van der Horst IC, van der Kallen CJ, van Greevenbroek MM, van Spil WE, Wijmenga C, Zhernakova A, Zwinderman AH, Sattar N, Jukema JW, van Duijn CM, Boomsma DI, Reinders MJ, Slagboom PE | 2020-10-01 | Genomic and Precision Medicine | |
| Serum fatty acid chain length associates with prevalent symptomatic end-stage osteoarthritis, independent of BMI. | Meessen JMTA, Saberi-Hosnijeh F, Bomer N, den Hollander W, van der Bom JG, van Hilten JA, van Spil WE, So-Osman C, Uitterlinden AG, Kloppenburg M, Nelissen RGHH, van Duijn CM, Slagboom PE, van Meurs JBJ, Meulenbelt I | 2020-09-22 | Scientific reports | |
| Effect of Thyroid Hormone Therapy on Fatigability in Older Adults With Subclinical Hypothyroidism: A Nested Study Within a Randomized Placebo-Controlled Trial. | Stuber MJ, Moutzouri E, Feller M, Del Giovane C, Bauer DC, Blum MR, Collet TH, Gussekloo J, Mooijaart SP, McCarthy VJC, Aujesky D, Westendorp R, Stott DJ, Glynn NW, Kearney PM, Rodondi N | 2020-09-16 | Fatigue, Levothyroxine, Thyroid disease | The journals of gerontology. Series A, Biological sciences and medical sciences |
| Refining Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder Genetic Loci by Integrating Summary Data From Genome-wide Association, Gene Expression, and DNA Methylation Studies. | Hammerschlag AR, Byrne EM, Bartels M, Wray NR, Middeldorp CM | 2020-09-15 | Fetal brain, Pleiotropy, Psychiatric disorders, SMR, eQTL, mQTL | Biological psychiatry |
| Cost-effectiveness of the Namaste care family program for nursing home residents with advanced dementia in comparison with usual care: a cluster-randomized controlled trial. | El Alili M, Smaling HJA, Joling KJ, Achterberg WP, Francke AL, Bosmans JE, van der Steen JT | 2020-09-04 | Cluster randomized controlled trial, Cost-benefit analysis, Dementia, Family caregiving, Namaste care, Nursing home, Palliative care, Person-centered care, Quality of life | BMC health services research |
| Activation of cytotoxic T cell population and inversion of CD4:CD8 ratio as manifestations of cellular immune response in SARS-COV-2 infection. | Khan F, van den Akker T, Hussein S, Marcellino BK, Khattar P, Glicksberg BS, Nadkarni GN, Firpo-Betancourt A, El Jamal SM | 2020-09-01 | Journal of hematopathology | |
| Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference. | Hop PJ, Luijk R, Daxinger L, van Iterson M, Dekkers KF, Jansen R, van Meurs JBJ, 't Hoen PAC, Ikram MA, van Greevenbroek MMJ, Boomsma DI, Slagboom PE, Veldink JH, van Zwet EW, Heijmans BT | 2020-08-28 | Causal inference, Chromatin, DNA methylation, Epigenetic regulation, Functional genomics, Genetic instrumental variable, Pleiotropy, Transcription factor | Genome biology |
| Proteome-wide assessment of diabetes mellitus in Qatari identifies IGFBP-2 as a risk factor already with early glycaemic disturbances. | Noordam R, van Heemst D, Suhre K, Krumsiek J, Mook-Kanamori DO | 2020-08-15 | Case-control study, Diabetes mellitus, Mendelian randomization, Metabolomics, Proteomics | Archives of biochemistry and biophysics |
| The contribution of tissue-grouped BMI-associated gene sets to cardiometabolic-disease risk: a Mendelian randomization study. | Verkouter I, de Mutsert R, Smit RAJ, Trompet S, Rosendaal FR, van Heemst D, Willems van Dijk K, Noordam R | 2020-08-01 | Mendelian randomization analysis, anthropometry, body mass index, coronary artery disease, type 2 diabetes mellitus, waist circumference | International journal of epidemiology |
| Genome-Wide Association Study of the Postprandial Triglyceride Response Yields Common Genetic Variation in LIPC (Hepatic Lipase). | Ibi D, Noordam R, van Klinken JB, Li-Gao R, de Mutsert R, Trompet S, Christen T, Blauw LL, van Heemst D, Mook-Kanamori DO, Rosendaal FR, Jukema JW, Dollé MET, Rensen PCN, van Dijk KW | 2020-08-01 | Genome-wide association studies, cardiovascular diseases, hepatic lipase, lipoprotein metabolism, metabolites, postprandial triglyceride response | Circulation. Genomic and precision medicine |
| Maternal near-miss surveillance, Namibia. | Heemelaar S, Josef M, Diener Z, Chipeio M, Stekelenburg J, van den Akker T, Mackenzie S | 2020-08-01 | Bulletin of the World Health Organization | |
| Geriatric Screening, Triage Urgency, and 30-Day Mortality in Older Emergency Department Patients. | Blomaard LC, Speksnijder C, Lucke JA, de Gelder J, Anten S, Schuit SCE, Steyerberg EW, Gussekloo J, de Groot B, Mooijaart SP | 2020-08-01 | emergency department, geriatric assessment, geriatric emergency medicine, risk stratification, triage | Journal of the American Geriatrics Society |
| The role of C-reactive protein, adiponectin and leptin in the association between abdominal adiposity and insulin resistance in middle-aged individuals. | Noordam R, Boersma V, Verkouter I, le Cessie S, Christen T, Lamb HJ, Rosendaal FR, Willems van Dijk K, van Heemst D, de Mutsert R | 2020-07-24 | Abdominal obesity, Adipokines, Epidemiology, Inflammation, Insulin resistance | Nutrition, metabolism, and cardiovascular diseases : NMCD |
| Socioeconomic differences in caesarean section – are they explained by medical need? An analysis of patient record data of a large Kenyan hospital. | van der Spek L, Sanglier S, Mabeya HM, van den Akker T, Mertens PLJM, Houweling TAJ | 2020-07-08 | Africa, Caesarean section, Clinical category, Delivery, Developing countries, Epidemiology, General obstetric, General obstetrics, Health equity, Maternity services, Obstetrics and gynaecology, Pregnancy, Socioeconomic factors | International journal for equity in health |
| Familial Longevity is Associated with an Attenuated Thyroidal Response to Recombinant Human Thyroid Stimulating Hormone. | Zutinic A, Pijl H, Ballieux BE, Roelfsema F, Westendorp RGJ, Blauw GJ, van Heemst D | 2020-07-01 | Thyroid, longevity, recombinant human TSH, responsivity | The Journal of clinical endocrinology and metabolism |
| Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood. | Zheng Y, Huang T, Wang T, Mei Z, Sun Z, Zhang T, Ellervik C, Chai JF, Sim X, van Dam RM, Tai ES, Koh WP, Dorajoo R, Saw SM, Sabanayagam C, Wong TY, Gupta P, Rossing P, Ahluwalia TS, Vinding RK, Bisgaard H, Bønnelykke K, Wang Y, Graff M, Voortman T, van Rooij FJA, Hofman A, van Heemst D, Noordam R, Estampador AC, Varga TV, Enzenbach C, Scholz M, Thiery J, Burkhardt R, Orho-Melander M, Schulz CA, Ericson U, Sonestedt E, Kubo M, Akiyama M, Zhou A, Kilpeläinen TO, Hansen T, Kleber ME, Delgado G, McCarthy M, Lemaitre RN, Felix JF, Jaddoe VWV, Wu Y, Mohlke KL, Lehtimäki T, Wang CA, Pennell CE, Schunkert H, Kessler T, Zeng L, Willenborg C, Peters A, Lieb W, Grote V, Rzehak P, Koletzko B, Erdmann J, Munz M, Wu T, He M, Yu C, Lecoeur C, Froguel P, Corella D, Moreno LA, Lai CQ, Pitkänen N, Boreham CA, Ridker PM, Rosendaal FR, de Mutsert R, Power C, Paternoster L, Sørensen TIA, Tjønneland A, Overvad K, Djousse L, Rivadeneira F, Lee NR, Raitakari OT, Kähönen M, Viikari J, Langhendries JP, Escribano J, Verduci E, Dedoussis G, König I, Balkau B, Coltell O, Dallongeville J, Meirhaeghe A, Amouyel P, Gottrand F, Pahkala K, Niinikoski H, Hyppönen E, März W, Mackey DA, Gruszfeld D, Tucker KL, Fumeron F, Estruch R, Ordovas JM, Arnett DK, Mook-Kanamori DO, Mozaffarian D, Psaty BM, North KE, Chasman DI, Qi L | 2020-07-01 | Birthweight, Blood pressure, Causal association, Hypertension, Mendelian randomization | European journal of epidemiology |
| Geriatric Screeners 2.0: Time for a Paradigm Shift in Emergency Department Vulnerability Research. | Carpenter CR, Mooijaart SP | 2020-07-01 | Journal of the American Geriatrics Society | |
| The Impact of Levothyroxine on Cardiac Function in Older Adults With Mild Subclinical Hypothyroidism: A Randomized Clinical Trial. | Gencer B, Moutzouri E, Blum MR, Feller M, Collet TH, Delgiovane C, da Costa BR, Buffle E, Monney P, Gabus V, Müller H, Sykiotis GP, Kearney P, Gussekloo J, Westendorp R, Stott DJ, Bauer DC, Rodondi N | 2020-07-01 | Clinical trials, Heart failure, Levothyroxine, Subclinical hypothyroidism, Thyroid | The American journal of medicine |
| Cerebral cortical microinfarcts: A novel MRI marker of vascular brain injury in patients with heart failure. | Ferro D, van den Brink H, Amier R, van Buchem M, de Bresser J, Bron E, Brunner-La Rocca HP, Hooghiemstra A, Marcks N, van Rossum A, Biessels GJ | 2020-07-01 | Atherosclerosis, Cerebrovascular disease/stroke, Cognitive impairment, Embolism, Heart failure | International journal of cardiology |
| Impact of visuospatial neglect post-stroke on daily activities, participation and informal caregiver burden: A systematic review. | Bosma MS, Nijboer TCW, Caljouw MAA, Achterberg WP | 2020-07-01 | Activities of daily living, Caregiver burden, Participation, Stroke, Unilateral neglect, Visuospatial neglect | Annals of physical and rehabilitation medicine |
| Beyond No Blame: Practical Challenges of Conducting Maternal and Perinatal Death Reviews in Eastern Ethiopia. | Tura AK, Fage SG, Ibrahim AM, Mohamed A, Ahmed R, Gure T, Zwart J, van den Akker T | 2020-06-30 | Global health, science and practice | |
| Biomarkers versus traditional risk factors to predict cardiovascular events in very old adults: cross-validated prospective cohort study. | Vaes B, Indestege P, Serneels T, Hegendörfer E, van Peet PG, Poortvliet RKE, Wallemacq P, Gussekloo J, Degryse J | 2020-06-28 | cardiac epidemiology, epidemiology, geriatric medicine | BMJ open |
| L-Thyroxine Therapy for Older Adults With Subclinical Hypothyroidism and Hypothyroid Symptoms: Secondary Analysis of a Randomized Trial. | de Montmollin M, Feller M, Beglinger S, McConnachie A, Aujesky D, Collet TH, Ford I, Gussekloo J, Kearney PM, McCarthy VJC, Mooijaart S, Poortvliet RKE, Quinn T, Stott DJ, Watt T, Westendorp R, Rodondi N, Bauer DC | 2020-06-02 | Annals of internal medicine | |
| Information needs of older patients living with chronic obstructive pulmonary disease (COPD) indicated for a specific geriatric rehabilitation programme: a prospective cohort study. | Wouters TJ, van Dam van Isselt EF, Achterberg WP | 2020-06-02 | Advanced COPD, Geriatric rehabilitation, Health status, Pulmonary rehabilitation, Self-management | International journal of palliative nursing |
| Longevity Relatives Count score identifies heritable longevity carriers and suggests case improvement in genetic studies. | van den Berg N, Rodríguez-Girondo M, Mandemakers K, Janssens AAPO, Beekman M, Slagboom PE | 2020-06-01 | aging, family tree, genetics, inheritance, longevity | Aging cell |
| Genetics and Not Shared Environment Explains Familial Resemblance in Adult Metabolomics Data. | Pool R, Hagenbeek FA, Hendriks AM, van Dongen J, Willemsen G, de Geus E, Willems van Dijk K, Verhoeven A, Suchiman HE, Beekman M, Slagboom PE, Harms AC, Hankemeier T, Boomsma DI | 2020-06-01 | Classical twin design, enrichment analysis, heritability, metabolite classes, shared environment | Twin research and human genetics : the official journal of the International Society for Twin Studies |
| Maternal mortality due to cardiac disease in low- and middle-income countries. | Heemelaar S, Petrus A, Knight M, van den Akker T | 2020-06-01 | cardiac disease, low- and middle-income countries, maladie cardiaque, maternal mortality, mortalité maternelle, pays à revenu faible ou intermédiaire | Tropical medicine & international health : TM & IH |
| Surviving mothers and lost babies – burden of stillbirths and neonatal deaths among women with maternal near miss in eastern Ethiopia: a prospective cohort study. | Tura AK, Scherjon S, van Roosmalen J, Zwart J, Stekelenburg J, van den Akker T | 2020-06-01 | Journal of global health | |
| Voices from the frontline: findings from a thematic analysis of a rapid online global survey of maternal and newborn health professionals facing the COVID-19 pandemic. | Semaan A, Audet C, Huysmans E, Afolabi B, Assarag B, Banke-Thomas A, Blencowe H, Caluwaerts S, Campbell OMR, Cavallaro FL, Chavane L, Day LT, Delamou A, Delvaux T, Graham WJ, Gon G, Kascak P, Matsui M, Moxon S, Nakimuli A, Pembe A, Radovich E, van den Akker T, Benova L | 2020-06-01 | child health, cross-sectional survey, health services research, health systems, maternal health | BMJ global health |
| The Challenges of Managing Inflammatory Bowel Diseases in Older Patients. | Asscher VER, E van der Meulen-de Jong A, Mooijaart SP | 2020-06-01 | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association | |
| Lifestyle-Intervention-Induced Reduction of Abdominal Fat Is Reflected by a Decreased Circulating Glycerol Level and an Increased HDL Diameter. | Beekman M, Schutte BAM, Akker EBVD, Noordam R, Dibbets-Schneider P, de Geus-Oei LF, Deelen J, Rest OV, Heemst DV, Feskens EJM, Slagboom PE | 2020-05-01 | abdominal fat, biomarkers, lifestyle interventions, metabolomics | Molecular nutrition & food research |
| Evaluation of mode of birth in pregnant women with heart disease. | Petrus AHJ, Jongert BL, Kiès P, Sueters M, Jongbloed MRM, Vliegen HW, Schalij MJ, van Lith J, van den Akker T | 2020-05-01 | Heart disease, Mode of birth, Pregnancy, Pregnancy outcomes | European journal of obstetrics, gynecology, and reproductive biology |
| Frequency and management of maternal infection in health facilities in 52 countries (GLOSS): a 1-week inception cohort study. | 2020-05-01 | The Lancet. Global health | ||
| Variations in use of childbirth interventions in 13 high-income countries: A multinational cross-sectional study. | Seijmonsbergen-Schermers AE, van den Akker T, Rydahl E, Beeckman K, Bogaerts A, Binfa L, Frith L, Gross MM, Misselwitz B, Hálfdánsdóttir B, Daly D, Corcoran P, Calleja-Agius J, Calleja N, Gatt M, Vika Nilsen AB, Declercq E, Gissler M, Heino A, Lindgren H, de Jonge A | 2020-05-01 | PLoS medicine | |
| Effectiveness of intramuscular gluteal glucocorticoid injection versus intra-articular glucocorticoid injection in knee osteoarthritis: design of a multicenter randomized, 24 weeks comparative parallel-group trial. | Mol MF, Runhaar J, Bos PK, Dorleijn DMJ, Vis M, Gussekloo J, Bindels PJE, Bierma-Zeinstra SMA | 2020-04-11 | General practice, Glucocorticoid injection, Intra-articular, Intramuscular, Knee osteoarthritis, Non-inferiority, Primary care, Randomized controlled trial | BMC musculoskeletal disorders |
| Patterns and characteristics of cognitive functioning in older patients approaching end stage kidney disease, the COPE-study. | van Deudekom FJ, Kallenberg MH, Berkhout-Byrne NC, Blauw GJ, Boom H, de Bresser J, van Buchem MA, Gaasbeek A, Hammer S, Lagro J, van Osch MJP, Witjes-Ané MN, Rabelink TJ, van Buren M, Mooijaart SP | 2020-04-09 | Cognitive function, End stage renal disease, Geriatric assessment, Geriatrics, Older patients | BMC nephrology |
| Association of handgrip strength with patient-reported outcome measures after total hip and knee arthroplasty. | Meessen JMTA, Fiocco M, Tordoir RL, Sjer A, Verdegaal SHM, Slagboom PE, Vliet Vlieland TPM, Nelissen RGHH | 2020-04-01 | Handgrip strength (HGS), Osteoarthritis (OA), Rehabilitation, Total hip arthroplasty (THA), Total knee arthroplasty (TKA) | Rheumatology international |
| A data-driven methodology reveals novel myofiber clusters in older human muscles. | Raz Y, van den Akker EB, Roest T, Riaz M, van de Rest O, Suchiman HED, Lakenberg N, Stassen SA, van Putten M, Feskens EJM, Reinders MJT, Goeman J, Beekman M, Raz V, Slagboom PE | 2020-04-01 | RNA-sequencing, bioinformatics, clustering, fibertyping, human, muscle, muscle health, myofiber, myosin heavy chain, sarcomere | FASEB journal : official publication of the Federation of American Societies for Experimental Biology |
| Repeat UVA exposure of human skin fibroblasts induces both a transitionary and recovery DNA methylation response. | Tilburg J, Slieker RC, Suchiman HED, Heath A, Heemst DV, Slagboom PE, de Gruijl FR, Gunn DA, Heijmans BT | 2020-04-01 | UVA irradiation, dermis, fibroblasts, genome-wide DNA methylation, photoaging, skin aging | Epigenomics |
| Interrelationships Between Pituitary Hormones as Assessed From 24-hour Serum Concentrations in Healthy Older Subjects. | van der Spoel E, Roelfsema F, Akintola AA, Jansen SW, Slagboom PE, Westendorp RGJ, Blauw GJ, Pijl H, van Heemst D | 2020-04-01 | cross-approximate entropy, cross-correlation, familial longevity, human, pituitary hormones, time series data | The Journal of clinical endocrinology and metabolism |
| Effect of Fixed-Density Thresholding on Structural Brain Networks: A Demonstration in Cerebral Small Vessel Disease. | de Brito Robalo BM, Vlegels N, Meier J, Leemans A, Biessels GJ, Reijmer YD | 2020-04-01 | brain connectivity, cerebral small vessel disease, diffusion tensor imaging, network density, network thresholding | Brain connectivity |
| European consensus on core principles and future priorities for geriatric rehabilitation: consensus statement. | Grund S, Gordon AL, van Balen R, Bachmann S, Cherubini A, Landi F, Stuck AE, Becker C, Achterberg WP, Bauer JM, Schols JMGA | 2020-04-01 | EuGMS, European consensus, Frailty, Functional decline, Geriatric rehabilitation | European geriatric medicine |
| Author Correction: Heritability estimates for 361 blood metabolites across 40 genome-wide association studies. | Hagenbeek FA, Pool R, van Dongen J, Draisma HM, Jan Hottenga J, Willemsen G, Abdellaoui A, Fedko IO, den Braber A, Visser PJ, de Geus EJCN, Willems van Dijk K, Verhoeven A, Suchiman HE, Beekman M, Slagboom PE, van Duijn CM, Harms AC, Hankemeier T, Bartels M, Nivard MG, Boomsma DI | 2020-03-31 | Nature communications | |
| The modified functional comorbidity index performed better than the Charlson index and original functional comorbidity index in predicting functional outcome in geriatric rehabilitation: a prospective observational study. | Kabboord AD, Godfrey D, Gordon AL, Gladman JRF, Van Eijk M, van Balen R, Achterberg WP | 2020-03-29 | BMC geriatrics | |
| Ventricular Repolarization is Associated with Cognitive Function, but Not with Cognitive Decline and Brain Magnetic Resonance Imaging (MRI) Measurements in Older Adults. | Zonneveld MH, Noordam R, Grond JV, Sabayan B, Mooijaart SP, Mcfarlane PW, Jukema JW, Trompet S | 2020-03-26 | MRI, cardiovascular disease, cognitive dysfunction, older adults, prolonged QT interval | Journal of clinical medicine |
| Treatment of Older Adults With Subclinical Hypothyroidism-Reply. | Mooijaart SP, Du Puy RS | 2020-03-17 | JAMA | |
| Arterial CO2 pressure changes during hypercapnia are associated with changes in brain parenchymal volume. | van der Kleij LA, De Vis JB, de Bresser J, Hendrikse J, Siero JCW | 2020-03-09 | Brain, Cerebral blood volume, Healthy volunteers, Hypercapnia, Intracranial pressure, Magnetic resonance imaging | European radiology experimental |
| Genome-wide analysis of constitutional DNA methylation in familial melanoma. | Salgado C, Gruis N, Heijmans BT, Oosting J, van Doorn R | 2020-03-06 | DNA methylation, Epimutation, Familial melanoma, Loss of imprinting | Clinical epigenetics |
| Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length. | Li C, Stoma S, Lotta LA, Warner S, Albrecht E, Allione A, Arp PP, Broer L, Buxton JL, Da Silva Couto Alves A, Deelen J, Fedko IO, Gordon SD, Jiang T, Karlsson R, Kerrison N, Loe TK, Mangino M, Milaneschi Y, Miraglio B, Pervjakova N, Russo A, Surakka I, van der Spek A, Verhoeven JE, Amin N, Beekman M, Blakemore AI, Canzian F, Hamby SE, Hottenga JJ, Jones PD, Jousilahti P, Mägi R, Medland SE, Montgomery GW, Nyholt DR, Perola M, Pietiläinen KH, Salomaa V, Sillanpää E, Suchiman HE, van Heemst D, Willemsen G, Agudo A, Boeing H, Boomsma DI, Chirlaque MD, Fagherazzi G, Ferrari P, Franks P, Gieger C, Eriksson JG, Gunter M, Hägg S, Hovatta I, Imaz L, Kaprio J, Kaaks R, Key T, Krogh V, Martin NG, Melander O, Metspalu A, Moreno C, Onland-Moret NC, Nilsson P, Ong KK, Overvad K, Palli D, Panico S, Pedersen NL, Penninx BWJH, Quirós JR, Jarvelin MR, Rodríguez-Barranco M, Scott RA, Severi G, Slagboom PE, Spector TD, Tjonneland A, Trichopoulou A, Tumino R, Uitterlinden AG, van der Schouw YT, van Duijn CM, Weiderpass E, Denchi EL, Matullo G, Butterworth AS, Danesh J, Samani NJ, Wareham NJ, Nelson CP, Langenberg C, Codd V | 2020-03-05 | Mendelian randomisation, age-related disease, biological aging, telomere length | American journal of human genetics |
| The association of kidney function and cognitive decline in older patients at risk of cardiovascular disease: a longitudinal data analysis. | Zijlstra LE, Trompet S, Mooijaart SP, van Buren M, Sattar N, Stott DJ, Jukema JW | 2020-03-05 | Chronic kidney disease, Cognitive function, Vascular disease | BMC nephrology |
| Metabolomics analyses in non-diabetic middle-aged individuals reveal metabolites impacting early glucose disturbances and insulin sensitivity. | Bos MM, Noordam R, Bennett K, Beekman M, Mook-Kanamori DO, Willems van Dijk K, Slagboom PE, Lundstedt T, Surowiec I, van Heemst D | 2020-03-02 | Glucose metabolism, Insulin sensitivity, Metabolomics, Type 2 diabetes mellitus | Metabolomics : Official journal of the Metabolomic Society |
| Metabolomics Profile in Depression: A Pooled Analysis of 230 Metabolic Markers in 5283 Cases With Depression and 10,145 Controls. | Bot M, Milaneschi Y, Al-Shehri T, Amin N, Garmaeva S, Onderwater GLJ, Pool R, Thesing CS, Vijfhuizen LS, Vogelzangs N, Arts ICW, Demirkan A, van Duijn C, van Greevenbroek M, van der Kallen CJH, Köhler S, Ligthart L, van den Maagdenberg AMJM, Mook-Kanamori DO, de Mutsert R, Tiemeier H, Schram MT, Stehouwer CDA, Terwindt GM, Willems van Dijk K, Fu J, Zhernakova A, Beekman M, Slagboom PE, Boomsma DI, Penninx BWJH | 2020-03-01 | Biomarkers, Cardiovascular, Depression, Metabolites, Metabolomics, Pooled analysis | Biological psychiatry |
| Predictive value of traditional risk factors for cardiovascular disease in older people: A systematic review. | van Bussel EF, Hoevenaar-Blom MP, Poortvliet RKE, Gussekloo J, van Dalen JW, van Gool WA, Richard E, Moll van Charante EP | 2020-03-01 | Cardiovascular disease, Older people, Prediction, Reversed epidemiology, Systematic review, Traditional risk factors | Preventive medicine |
| A characterization of cis- and trans-heritability of RNA-Seq-based gene expression. | Ouwens KG, Jansen R, Nivard MG, van Dongen J, Frieser MJ, Hottenga JJ, Arindrarto W, Claringbould A, van Iterson M, Mei H, Franke L, Heijmans BT, A C 't Hoen P, van Meurs J, Brooks AI, Penninx BWJH, Boomsma DI | 2020-02-01 | European journal of human genetics : EJHG | |
| Bone marrow morphologic features, MyPRS, and gene mutation correlations in plasma cell myeloma. | Hao Y, Khaykin D, Machado L, van den Akker T, Houldsworth J, Barlogie B, Hussein S, El Jamal SM, Petersen B, Teruya-Feldstein J | 2020-02-01 | Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc | |
| Physiological-based cord clamping in very preterm infants – Randomised controlled trial on effectiveness of stabilisation. | Knol R, Brouwer E, van den Akker T, DeKoninck P, van Geloven N, Polglase GR, Lopriore E, Herkert E, Reiss IKM, Hooper SB, Te Pas AB | 2020-02-01 | Resuscitation | |
| The APOP screener and clinical outcomes in older hospitalised internal medicine patients. | Blomaard LC, Lucke JA, de Gelder J, Anten S, Alsma J, Schuit SCE, Gussekloo J, de Groot B, Mooijaart SP | 2020-02-01 | The Netherlands journal of medicine | |
| MRI phenotypes of the brain are related to future stroke and mortality in patients with manifest arterial disease: The SMART-MR study. | Jaarsma-Coes MG, Ghaznawi R, Hendrikse J, Slump C, Witkamp TD, van der Graaf Y, Geerlings MI, de Bresser J | 2020-02-01 | Brain imaging, atherosclerosis, cluster analysis, magnetic resonance imaging, patient outcome | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism |
| Observational pain assessment in older persons with dementia in four countries: Observer agreement of items and factor structure of the Pain Assessment in Impaired Cognition. | de Waal MWM, van Dalen-Kok AH, de Vet HCW, Gimenez-Llort L, Konstantinovic L, de Tommaso M, Fischer T, Lukas A, Kunz M, Lautenbacher S, Lobbezoo F, McGuire BE, van der Steen JT, Achterberg WP | 2020-02-01 | European journal of pain (London, England) | |
| Recommendations for (Discontinuation of) Statin Treatment in Older Adults: Review of Guidelines. | van der Ploeg MA, Floriani C, Achterberg WP, Bogaerts JMK, Gussekloo J, Mooijaart SP, Streit S, Poortvliet RKE, Drewes YM | 2020-02-01 | cardiovascular diseases, clinical decision making, drug therapy, hydroxymethylglutaryl-CoA reductase inhibitors, prevention | Journal of the American Geriatrics Society |
| Heritability estimates for 361 blood metabolites across 40 genome-wide association studies. | Hagenbeek FA, Pool R, van Dongen J, Draisma HHM, Jan Hottenga J, Willemsen G, Abdellaoui A, Fedko IO, den Braber A, Visser PJ, de Geus EJCN, Willems van Dijk K, Verhoeven A, Suchiman HE, Beekman M, Slagboom PE, van Duijn CM, Harms AC, Hankemeier T, Bartels M, Nivard MG, Boomsma DI | 2020-01-07 | Nature communications | |
| Association Between Blood Pressure Variability and Cerebral Small-Vessel Disease: A Systematic Review and Meta-Analysis. | Tully PJ, Yano Y, Launer LJ, Kario K, Nagai M, Mooijaart SP, Claassen JAHR, Lattanzi S, Vincent AD, Tzourio C | 2020-01-07 | blood pressure measurement/monitoring, blood pressure variability, high blood pressure, meta‐analysis, systematic review, white matter disease | Journal of the American Heart Association |
| Association of cardiovascular structure and function with cerebrovascular changes and cognitive function in older patients with end-stage renal disease. | Zijlstra LE, Trompet S, Jukema JW, Kroft LJM, de Bresser J, van Osch MJP, Hammer S, Witjes MN, van Buren M, Mooijaart SP | 2020-01-07 | arterial stiffness, cerebrovascular changes, dementia, end stage renal disease, systolic heart function | Aging |
| Major obstetric haemorrhage in Metro East, Cape Town, South Africa: a population-based cohort study using the maternal near-miss approach. | Heitkamp A, Aronson SL, van den Akker T, Vollmer L, Gebhardt S, van Roosmalen J, de Vries JI, Theron G | 2020-01-06 | Caesarean section, Major obstetric haemorrhage, Maternal near-miss, Placental abruption | BMC pregnancy and childbirth |
| Increasing utilisation of perinatal services: estimating the impact of community health worker program in Neno, Malawi. | Kachimanga C, Dunbar EL, Watson S, Cundale K, Makungwa H, Wroe EB, Malindi C, Nazimera L, Palazuelos D, Drake J, Gates T, van den Akker T, Shea J | 2020-01-06 | Antenatal care, Community health workers, Deliveries, obstetric, Intrapartum care, Malawi, Maternal mortality, Perinatal care, Postnatal care, Synthetic control, quasi-experimental study | BMC pregnancy and childbirth |
| Pre-post implementation survey of a multicomponent intervention to improve informed consent for caesarean section in Southern Malawi. | Zethof S, Bakker W, Nansongole F, Kilowe K, van Roosmalen J, van den Akker T | 2020-01-06 | caesarean section, informed consent, maternal medicine, medical ethics, quality in health care, tropical medicine | BMJ open |
| Men Have a Stronger Monocyte-Derived Cytokine Production Response upon Stimulation with the Gram-Negative Stimulus Lipopolysaccharide than Women: A Pooled Analysis Including 15 Study Populations. | Beenakker KGM, Westendorp RGJ, de Craen AJM, Chen S, Raz Y, Ballieux BEPB, Nelissen RGHH, Later AFL, Huizinga TW, Slagboom PE, Boomsma DI, Maier AB | 2020-01-01 | Blood, Cytokines, Gender, Innate immunity, Lipopolysaccharide, Sex | Journal of innate immunity |
| Basal cell carcinoma genetic susceptibility increases the rate of skin ageing: a Mendelian randomization study. | van der Poort EKJ, Gunn DA, Beekman M, Griffiths CEM, Slagboom PE, van Heemst D, Noordam R | 2020-01-01 | Journal of the European Academy of Dermatology and Venereology : JEADV | |
| Ageing, age-related diseases and oxidative stress: What to do next? | Luo J, Mills K, le Cessie S, Noordam R, van Heemst D | 2020-01-01 | Age-related diseases, Ageing, Oxidative stress, Vitamin E metabolites | Ageing research reviews |
| Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas. | Liu J, Lahousse L, Nivard MG, Bot M, Chen L, van Klinken JB, Thesing CS, Beekman M, van den Akker EB, Slieker RC, Waterham E, van der Kallen CJH, de Boer I, Li-Gao R, Vojinovic D, Amin N, Radjabzadeh D, Kraaij R, Alferink LJM, Murad SD, Uitterlinden AG, Willemsen G, Pool R, Milaneschi Y, van Heemst D, Suchiman HED, Rutters F, Elders PJM, Beulens JWJ, van der Heijden AAWA, van Greevenbroek MMJ, Arts ICW, Onderwater GLJ, van den Maagdenberg AMJM, Mook-Kanamori DO, Hankemeier T, Terwindt GM, Stehouwer CDA, Geleijnse JM, 't Hart LM, Slagboom PE, van Dijk KW, Zhernakova A, Fu J, Penninx BWJH, Boomsma DI, Demirkan A, Stricker BHC, van Duijn CM | 2020-01-01 | Nature medicine | |
| Regional variations in childbirth interventions and their correlations with adverse outcomes, birthplace and care provider: A nationwide explorative study. | Seijmonsbergen-Schermers AE, Zondag DC, Nieuwenhuijze M, van den Akker T, Verhoeven CJ, Geerts CC, Schellevis FG, de Jonge A | 2020-01-01 | PloS one | |
| Severe Hypertensive Disorders of Pregnancy in Eastern Ethiopia: Comparing the Original WHO and Adapted sub-Saharan African Maternal Near-Miss Criteria. | Tura AK, Scherjon S, Stekelenburg J, van Roosmalen J, van den Akker T, Zwart J | 2020-01-01 | hypertensive disorders of pregnancy, maternal mortality, maternal near-miss, severe maternal outcomes, sub-Saharan Africa | International journal of women's health |
| The kidney, subclinical thyroid disease and cardiovascular outcomes in older patients. | Zijlstra LE, van Velzen DM, Simsek S, Mooijaart SP, van Buren M, Stott DJ, Ford I, Jukema JW, Trompet S | 2020-01-01 | cardiovascular disease, kidney function, older patients, thyroid function | Endocrine connections |
| Renal Impairment, Cardiovascular Disease, and the Short-Term Efficacy and Safety of PCSK9 Targeted by Inclisiran. | Zijlstra LE, Trompet S, Mooijaart SP, van Buren M, Jukema JW | 2020-01-01 | Mayo Clinic proceedings | |
| Skeletal Effects of Levothyroxine for Subclinical Hypothyroidism in Older Adults: A TRUST Randomized Trial Nested Study. | Gonzalez Rodriguez E, Stuber M, Del Giovane C, Feller M, Collet TH, Löwe AL, Blum MR, van Vliet NA, van Heemst D, Kearney PM, Gussekloo J, Mooijaart S, Westendorp RGJ, Stott DJ, Aeberli D, Bauer DC, Hans D, Rodondi N | 2020-01-01 | The Journal of clinical endocrinology and metabolism | |
| Managing hypertension in frail oldest-old-The role of guideline use by general practitioners from 29 countries. | Roulet C, Rozsnyai Z, Jungo KT, A van der Ploeg M, Floriani C, Kurpas D, Vinker S, Kreitmayer Pestic S, Petrazzuoli F, Hoffmann K, Viegas RPA, Mallen C, Tatsioni A, Maisonneuve H, Collins C, Lingner H, Tsopra R, Mueller Y, Poortvliet RKE, Gussekloo J, Streit S | 2020-01-01 | PloS one | |
| Potentially inappropriate medication and attitudes of older adults towards deprescribing. | Achterhof AB, Rozsnyai Z, Reeve E, Jungo KT, Floriani C, Poortvliet RKE, Rodondi N, Gussekloo J, Streit S | 2020-01-01 | PloS one | |
| Small vessel disease lesion type and brain atrophy: The role of co-occurring amyloid. | Heinen R, Groeneveld ON, Barkhof F, de Bresser J, Exalto LG, Kuijf HJ, Prins ND, Scheltens P, van der Flier WM, Biessels GJ | 2020-01-01 | Alzheimer's disease, brain atrophy, cerebral microbleeds, cerebral small vessel disease, lacunes, magnetic resonance imaging, vascular cognitive impairment, white matter hyperintensities | Alzheimer's & dementia (Amsterdam, Netherlands) |
| fMRI network correlates of predisposing risk factors for delirium: A cross-sectional study. | van Montfort SJT, Slooter AJC, Kant IMJ, van der Leur RR, Spies C, de Bresser J, Witkamp TD, Hendrikse J, van Dellen E | 2020-01-01 | Aging, Brain networks, Delirium, Functional connectivity, Graph theory, Risk factors | NeuroImage. Clinical |
| CSF enhancement on post-contrast fluid-attenuated inversion recovery images; a systematic review. | Freeze WM, van der Thiel M, de Bresser J, Klijn CJM, van Etten ES, Jansen JFA, van der Weerd L, Jacobs HIL, Backes WH, van Veluw SJ | 2020-01-01 | Blood–brain barrier, Cerebrospinal fluid, Fluid-attenuated inversion recovery, Gadolinium, Neurological disease | NeuroImage. Clinical |
| Cerebral Perfusion and the Burden of Small Vessel Disease in Patients Referred to a Memory Clinic. | Onkenhout L, Appelmans N, Kappelle LJ, Koek D, Exalto L, de Bresser J, Biessels GJ | 2020-01-01 | Cerebral perfusion, Enlarged perivascular spaces, Lacunes, Microbleeds, Small vessel disease, White matter hyperintesities | Cerebrovascular diseases (Basel, Switzerland) |
| Suspected Transverse Myelitis with Normal MRI and CSF Findings in a Patient with Lupus: What to Do? A Case Series and Systematic Review. | Monahan RC, Beaart HJL, Fronczek R, Terwindt GM, Beaart-van de Voorde LJJ, de Bresser J, Kloppenburg M, van der Wee NJA, Huizinga TWJ, Steup-Beekman GM | 2020-01-01 | CSF, MRI, lupus, neuropsychiatric, transverse myelitis | Neuropsychiatric disease and treatment |
| The Pain Assessment in Impaired Cognition scale (PAIC15): A multidisciplinary and international approach to develop and test a meta-tool for pain assessment in impaired cognition, especially dementia. | Kunz M, de Waal MWM, Achterberg WP, Gimenez-Llort L, Lobbezoo F, Sampson EL, van Dalen-Kok AH, Defrin R, Invitto S, Konstantinovic L, Oosterman J, Petrini L, van der Steen JT, Strand LI, de Tommaso M, Zwakhalen S, Husebo BS, Lautenbacher S | 2020-01-01 | European journal of pain (London, England) | |
| The Prognostic Value of Metabolic Profiling in Older Patients With a Proximal Femoral Fracture. | van der Sijp MPL, Suchiman HED, Eijk M, Vojinovic D, Niggebrugge AHP, Blauw GJ, Achterberg WP, Slagboom PE | 2020-01-01 | biomarkers, metabolic profiling, metabolomics, prognostics, proximal femoral fracture | Geriatric orthopaedic surgery & rehabilitation |
| Non-pharmacological interventions for improving quality of life of long-term care residents with dementia: a scoping review protocol. | Akintola AA, Achterberg WP, Caljouw MAA | 2019-12-23 | dementia, long-term care, non- pharmacological interventions, scoping review protocol | BMJ open |
| Confidential enquiries into maternal deaths in Ondo State, Nigeria – a comparative analysis. | Oyeneyin L, van den Akker T, Durojaiye O, Obaado O, Akanbiemu F, Olagbuji Y, Aladeniyi I, Oyeneyin M, Aladenola O | 2019-12-21 | Confidential enquiries, Maternal deaths, Maternal mortality ratio | BMC pregnancy and childbirth |
| PCSK9 inhibition in high-risk patients. | Zijlstra LE, Mooijaart SP, Jukema JW | 2019-12-11 | PCSK9 inhibiting, cardiovascular disease, lipid-lowering, older patients, plaque burden | Aging |
| Nutritional Factors Modulating Alu Methylation in an Italian Sample from The Mark-Age Study Including Offspring of Healthy Nonagenarians. | Giacconi R, Malavolta M, Bürkle A, Moreno-Villanueva M, Franceschi C, Capri M, Slagboom PE, Jansen EHJM, Dollé MET, Grune T, Weber D, Hervonen A, Stuetz W, Breusing N, Ciccarone F, Zampieri M, Aversano V, Caiafa P, Formentini L, Piacenza F, Pierpaoli E, Basso A, Provinciali M, Cardelli M | 2019-12-06 | Alu methylation, aging, antioxidant, longevity, nutrients | Nutrients |
| Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction. | Victorelli S, Lagnado A, Halim J, Moore W, Talbot D, Barrett K, Chapman J, Birch J, Ogrodnik M, Meves A, Pawlikowski JS, Jurk D, Adams PD, van Heemst D, Beekman M, Slagboom PE, Gunn DA, Passos JF | 2019-12-02 | SASP, melanocytes, senescence, skin ageing, telomeres | The EMBO journal |
| Repeat variations in polyglutamine disease-associated genes and cognitive function in old age. | Gardiner SL, Trompet S, Sabayan B, Boogaard MW, Jukema JW, Slagboom PE, Roos RAC, van der Grond J, Aziz NA | 2019-12-01 | Cognitive function, Huntington disease, Missing heritability, Polyglutamine diseases, Polyglutamine disease–associated genes, Tandem repeats | Neurobiology of aging |
| Viewpoint on the role of tissue maintenance in ageing: focus on biomarkers of bone, cartilage, muscle, and brain tissue maintenance. | van der Spoel E, van Vliet NA, van Heemst D | 2019-12-01 | Biomarkers, Bone, Brain, Cartilage, Muscle, Tissue maintenance | Ageing research reviews |
| CAM-ICU may not be the optimal screening tool for early delirium screening in older emergency department patients: a prospective cohort study. | Lucke JA, De Gelder J, Blomaard LC, Fogteloo AJ, Alsma J, Schuit SCE, Brink A, De Groot B, Blauw GJ, Mooijaart SP | 2019-12-01 | European journal of emergency medicine : official journal of the European Society for Emergency Medicine | |
| The association between lacunes and white matter hyperintensity features on MRI: The SMART-MR study. | Ghaznawi R, Geerlings MI, Jaarsma-Coes MG, Zwartbol MH, Kuijf HJ, van der Graaf Y, Witkamp TD, Hendrikse J, de Bresser J | 2019-12-01 | Small vessel disease, cerebrovascular disease, lacunes, magnetic resonance imaging, white matter hyperintensities | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism |
| Nonfocal Transient Neurological Attacks Are Associated With Cerebral Small Vessel Disease. | Oudeman EA, Greving JP, Van den Berg-Vos RM, Biessels GJ, Bron EE, van Oostenbrugge R, de Bresser J, Kappelle LJ | 2019-12-01 | cerebral small vessel diseases, humans, magnetic resonance imaging, neurologic manifestations, odds ratio | Stroke |
| What is geriatric rehabilitation and how should it be organized? A Delphi study aimed at reaching European consensus. | van Balen R, Gordon AL, Schols JMGA, Drewes YM, Achterberg WP | 2019-12-01 | Delphi procedure, European consensus, Geriatric rehabilitation | European geriatric medicine |
| We’re all different and we’re the same: the story of the European nursing home resident. | Achterberg WP, Everink IH, van der Steen JT, Gordon AL | 2019-12-01 | Age and ageing | |
| Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism. | Mooijaart SP, Du Puy RS, Stott DJ, Kearney PM, Rodondi N, Westendorp RGJ, den Elzen WPJ, Postmus I, Poortvliet RKE, van Heemst D, van Munster BC, Peeters RP, Ford I, Kean S, Messow CM, Blum MR, Collet TH, Watt T, Dekkers OM, Jukema JW, Smit JWA, Langhorne P, Gussekloo J | 2019-11-26 | JAMA | |
| [Screening for vulnerability in older adults attending the emergency department]. | van Dam CS, Trappenburg MC, Peters MJL, Blomaard LC, Lucke JA, Mooijaart SP | 2019-11-14 | Nederlands tijdschrift voor geneeskunde | |
| Performance of five automated white matter hyperintensity segmentation methods in a multicenter dataset. | Heinen R, Steenwijk MD, Barkhof F, Biesbroek JM, van der Flier WM, Kuijf HJ, Prins ND, Vrenken H, Biessels GJ, de Bresser J | 2019-11-14 | Scientific reports | |
| Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration. | Noordam R, Bos MM, Wang H, Winkler TW, Bentley AR, Kilpeläinen TO, de Vries PS, Sung YJ, Schwander K, Cade BE, Manning A, Aschard H, Brown MR, Chen H, Franceschini N, Musani SK, Richard M, Vojinovic D, Aslibekyan S, Bartz TM, de Las Fuentes L, Feitosa M, Horimoto AR, Ilkov M, Kho M, Kraja A, Li C, Lim E, Liu Y, Mook-Kanamori DO, Rankinen T, Tajuddin SM, van der Spek A, Wang Z, Marten J, Laville V, Alver M, Evangelou E, Graff ME, He M, Kühnel B, Lyytikäinen LP, Marques-Vidal P, Nolte IM, Palmer ND, Rauramaa R, Shu XO, Snieder H, Weiss S, Wen W, Yanek LR, Adolfo C, Ballantyne C, Bielak L, Biermasz NR, Boerwinkle E, Dimou N, Eiriksdottir G, Gao C, Gharib SA, Gottlieb DJ, Haba-Rubio J, Harris TB, Heikkinen S, Heinzer R, Hixson JE, Homuth G, Ikram MA, Komulainen P, Krieger JE, Lee J, Liu J, Lohman KK, Luik AI, Mägi R, Martin LW, Meitinger T, Metspalu A, Milaneschi Y, Nalls MA, O'Connell J, Peters A, Peyser P, Raitakari OT, Reiner AP, Rensen PCN, Rice TK, Rich SS, Roenneberg T, Rotter JI, Schreiner PJ, Shikany J, Sidney SS, Sims M, Sitlani CM, Sofer T, Strauch K, Swertz MA, Taylor KD, Uitterlinden AG, van Duijn CM, Völzke H, Waldenberger M, Wallance RB, van Dijk KW, Yu C, Zonderman AB, Becker DM, Elliott P, Esko T, Gieger C, Grabe HJ, Lakka TA, Lehtimäki T, North KE, Penninx BWJH, Vollenweider P, Wagenknecht LE, Wu T, Xiang YB, Zheng W, Arnett DK, Bouchard C, Evans MK, Gudnason V, Kardia S, Kelly TN, Kritchevsky SB, Loos RJF, Pereira AC, Province M, Psaty BM, Rotimi C, Zhu X, Amin N, Cupples LA, Fornage M, Fox EF, Guo X, Gauderman WJ, Rice K, Kooperberg C, Munroe PB, Liu CT, Morrison AC, Rao DC, van Heemst D, Redline S | 2019-11-12 | Nature communications | |
| [Assessment instruments in frail older patients; a call for more standardisation]. | Oud FMM, de Rooij SEJA, Arends AJ, Emmelot-Vonk MH, Melis RJF, Mooijaart SP, Willems HC, van Munster BC | 2019-11-12 | Nederlands tijdschrift voor geneeskunde | |
| Validated inference of smoking habits from blood with a finite DNA methylation marker set. | Maas SCE, Vidaki A, Wilson R, Teumer A, Liu F, van Meurs JBJ, Uitterlinden AG, Boomsma DI, de Geus EJC, Willemsen G, van Dongen J, van der Kallen CJH, Slagboom PE, Beekman M, van Heemst D, van den Berg LH, Duijts L, Jaddoe VWV, Ladwig KH, Kunze S, Peters A, Ikram MA, Grabe HJ, Felix JF, Waldenberger M, Franco OH, Ghanbari M, Kayser M | 2019-11-01 | DNA methylation, Epidemiology, Epigenetics, Forensics, Smoking inference | European journal of epidemiology |
| Comparison of outcome between intrauterine balloon tamponade and uterine artery embolization in the management of persistent postpartum hemorrhage: A propensity score-matched cohort study. | Ramler PI, Henriquez DDCA, van den Akker T, Caram-Deelder C, Groenwold RHH, Bloemenkamp KWM, van Roosmalen J, van Lith JMM, van der Bom JG | 2019-11-01 | intrauterine balloon tamponade, maternal mortality, peripartum hysterectomy, postpartum hemorrhage, propensity score, severe maternal outcome, uterine artery embolization | Acta obstetricia et gynecologica Scandinavica |
| Risk factors, management, and outcomes of amniotic fluid embolism: A multicountry, population-based cohort and nested case-control study. | Fitzpatrick KE, van den Akker T, Bloemenkamp KWM, Deneux-Tharaux C, Kristufkova A, Li Z, Schaap TP, Sullivan EA, Tuffnell D, Knight M | 2019-11-01 | PLoS medicine | |
| Standardized Assessment of Automatic Segmentation of White Matter Hyperintensities and Results of the WMH Segmentation Challenge. | Kuijf HJ, Biesbroek JM, De Bresser J, Heinen R, Andermatt S, Bento M, Berseth M, Belyaev M, Cardoso MJ, Casamitjana A, Collins DL, Dadar M, Georgiou A, Ghafoorian M, Jin D, Khademi A, Knight J, Li H, Llado X, Luna M, Mahmood Q, McKinley R, Mehrtash A, Ourselin S, Park BY, Park H, Park SH, Pezold S, Puybareau E, Rittner L, Sudre CH, Valverde S, Vilaplana V, Wiest R, Xu Y, Xu Z, Zeng G, Zhang J, Zheng G, Chen C, van der Flier W, Barkhof F, Viergever MA, Biessels GJ | 2019-11-01 | IEEE transactions on medical imaging | |
| Quality of Life and Pain Medication Use in Persons With Advanced Dementia Living in Long-Term Care Facilities. | van Dam PH, Caljouw MAA, Slettebø DD, Achterberg WP, Husebo BS | 2019-11-01 | Quality of life, dementia, nursing home, pain medication, paracetamol | Journal of the American Medical Directors Association |
| Systematic Review: Components of a Comprehensive Geriatric Assessment in Inflammatory Bowel Disease-A Potentially Promising but Often Neglected Risk Stratification. | Asscher VER, Lee-Kong FVY, Kort ED, van Deudekom FJ, Mooijaart SP, Maljaars PWJ | 2019-10-28 | Crohn’s disease, comprehensive geriatric assessment, ulcerative colitis | Journal of Crohn's & colitis |
| Clinical characteristics of women captured by extending the definition of severe postpartum haemorrhage with ‘refractoriness to treatment’: a cohort study. | Henriquez DDCA, Gillissen A, Smith SM, Cramer RA, van den Akker T, Zwart JJ, van Roosmalen JJM, Bloemenkamp KWM, van der Bom JG | 2019-10-17 | Definition, Maternal morbidity, Maternal mortality, Postpartum haemorrhage | BMC pregnancy and childbirth |
| Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults. | van Dongen J, Zilhão NR, Sugden K, Hannon EJ, Mill J, Caspi A, Agnew-Blais J, Arseneault L, Corcoran DL, Moffitt TE, Poulton R, Franke B, Boomsma DI | 2019-10-15 | ADHD, CAARS, DNA methylation, EWAS, Epigenetic, Meta-analysis | Biological psychiatry |
| The use of goal attainment scaling during clinical medication review in older persons with polypharmacy. | Verdoorn S, Blom J, Vogelzang T, Kwint HF, Gussekloo J, Bouvy ML | 2019-10-01 | Clinical medication review, Drug-related problems, Goal attainment scaling, Older persons, Patient-centred care, Polypharmacy | Research in social & administrative pharmacy : RSAP |
| Combined impact of future trends on healthcare utilisation of older people: A Delphi study. | Ravensbergen WM, Drewes YM, Hilderink HBM, Verschuuren M, Gussekloo J, Vonk RAA | 2019-10-01 | Ageing society, Delphi method, Healthcare planning, Population health foresight, Public health trends | Health policy (Amsterdam, Netherlands) |
| The Association between Adult Weight Gain and Insulin Resistance at Middle Age: Mediation by Visceral Fat and Liver Fat. | Verkouter I, Noordam R, le Cessie S, van Dam RM, Lamb HJ, Rosendaal FR, van Heemst D, de Mutsert R | 2019-09-28 | body weight changes, fatty liver, insulin resistance, visceral fat | Journal of clinical medicine |
| Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study. | Huang T, Wang T, Zheng Y, Ellervik C, Li X, Gao M, Fang Z, Chai JF, Ahluwalia TVS, Wang Y, Voortman T, Noordam R, Frazier-Wood A, Scholz M, Sonestedt E, Akiyama M, Dorajoo R, Zhou A, Kilpeläinen TO, Kleber ME, Crozier SR, Godfrey KM, Lemaitre R, Felix JF, Shi Y, Gupta P, Khor CC, Lehtimäki T, Wang CA, Tiesler CMT, Thiering E, Standl M, Rzehak P, Marouli E, He M, Lecoeur C, Corella D, Lai CQ, Moreno LA, Pitkänen N, Boreham CA, Zhang T, Saw SM, Ridker PM, Graff M, van Rooij FJA, Uitterlinden AG, Hofman A, van Heemst D, Rosendaal FR, de Mutsert R, Burkhardt R, Schulz CA, Ericson U, Kamatani Y, Yuan JM, Power C, Hansen T, Sørensen TIA, Tjønneland A, Overvad K, Delgado G, Cooper C, Djousse L, Rivadeneira F, Jameson K, Zhao W, Liu J, Lee NR, Raitakari O, Kähönen M, Viikari J, Grote V, Langhendries JP, Koletzko B, Escribano J, Verduci E, Dedoussis G, Yu C, Tham YC, Lim B, Lim SH, Froguel P, Balkau B, Fink NR, Vinding RK, Sevelsted A, Bisgaard H, Coltell O, Dallongeville J, Gottrand F, Pahkala K, Niinikoski H, Hyppönen E, Pedersen O, März W, Inskip H, Jaddoe VWV, Dennison E, Wong TY, Sabanayagam C, Tai ES, Mohlke KL, Mackey DA, Gruszfeld D, Deloukas P, Tucker KL, Fumeron F, Bønnelykke K, Rossing P, Estruch R, Ordovas JM, Arnett DK, Meirhaeghe A, Amouyel P, Cheng CY, Sim X, Teo YY, van Dam RM, Koh WP, Orho-Melander M, Loeffler M, Kubo M, Thiery J, Mook-Kanamori DO, Mozaffarian D, Psaty BM, Franco OH, Wu T, North KE, Davey Smith G, Chavarro JE, Chasman DI, Qi L | 2019-09-04 | JAMA network open | |
| Statement on Minimum Standards for the Care of Older People in Emergency Departments by the Geriatric Emergency Medicine Special Interest Group of the International Federation for Emergency Medicine – ERRATUM. | Ellis B, Carpenter CR, Lowthian JA, Mooijaart SP, Nickel CH, Melady D | 2019-09-01 | CJEM | |
| Associations of Elevated Antithyroperoxidase Antibodies with Thyroid Function, Survival, Functioning, and Depressive Symptoms in the Oldest Old: The Leiden 85-plus Study. | Du Puy RS, Poortvliet RKE, Snel M, den Elzen WPJ, Ballieux BEPB, Dekkers OM, Mooijaart SP, Gussekloo J | 2019-09-01 | Leiden 85-plus Study, TPOAb, antithyroperoxidase antibodies, oldest old, thyroid dysfunction | Thyroid : official journal of the American Thyroid Association |
| Physical Performance in Memory Clinic Patients: The Potential Role of the White Matter Network. | Verwer JH, Reijmer YD, Koek HL, Biessels GJ | 2019-09-01 | brain connectivity, cognitive impairment, diffusion-weighted imaging, gait | Journal of the American Geriatrics Society |
| Patient Characteristics and General Practitioners’ Advice to Stop Statins in Oldest-Old Patients: a Survey Study Across 30 Countries. | van der Ploeg MA, Streit S, Achterberg WP, Beers E, Bohnen AM, Burman RA, Collins C, Franco FG, Gerasimovska-Kitanovska B, Gintere S, Gomez Bravo R, Hoffmann K, Iftode C, Peštić SK, Koskela TH, Kurpas D, Maisonneuve H, Mallen CD, Merlo C, Mueller Y, Muth C, Petrazzuoli F, Rodondi N, Rosemann T, Sattler M, Schermer T, Šter MP, Švadlenková Z, Tatsioni A, Thulesius H, Tkachenko V, Torzsa P, Tsopra R, Tuz C, Vaes B, Viegas RPA, Vinker S, Wallis KA, Zeller A, Gussekloo J, Poortvliet RKE | 2019-09-01 | cardiovascular diseases, clinical decision-making, drug therapy, general practitioners, hydroxymethylglutaryl-CoA reductase inhibitors, palliative care | Journal of general internal medicine |
| Pain assessment in impaired cognition: observer agreement in a long-term care setting in patients with dementia. | van Dalen-Kok AH, Achterberg WP, Rijkmans WE, de Vet HC, de Waal MW | 2019-09-01 | dementia, interobserver agreement, intraobserver agreement, nursing home, observational measurement instrument, pain, pain assessment, reliability | Pain management |
| How can the quality of life of older patients living with chronic pain be improved? | Achterberg WP | 2019-09-01 | multimorbidity dementia, pain assessment, pain management, quality of life | Pain management |
| Quality of essential newborn care and neonatal resuscitation at health facilities in Afghanistan: a cross-sectional assessment. | Atiqzai F, Manalai P, Amin SS, Edmond KM, Naziri M, Soroush MS, Sultana S, Yousufi K, van den Akker T, Stekelenburg J, Tappis H | 2019-08-30 | Afghanistan, essential newborn care, healthcare quality assessment, neonatal resuscitation, quality of healthcare | BMJ open |
| Mistreatment of women in public health facilities of Ethiopia. | Sheferaw ED, Kim YM, van den Akker T, Stekelenburg J | 2019-08-27 | Disrespect and abuse, Ethiopia, Mistreatment, Respectful maternity care | Reproductive health |
| Fast LC-ESI-MS/MS analysis and influence of sampling conditions for gut metabolites in plasma and serum. | van der Laan T, Kloots T, Beekman M, Kindt A, Dubbelman AC, Harms A, van Duijn CM, Slagboom PE, Hankemeier T | 2019-08-26 | Scientific reports | |
| A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals. | Deelen J, Kettunen J, Fischer K, van der Spek A, Trompet S, Kastenmüller G, Boyd A, Zierer J, van den Akker EB, Ala-Korpela M, Amin N, Demirkan A, Ghanbari M, van Heemst D, Ikram MA, van Klinken JB, Mooijaart SP, Peters A, Salomaa V, Sattar N, Spector TD, Tiemeier H, Verhoeven A, Waldenberger M, Würtz P, Davey Smith G, Metspalu A, Perola M, Menni C, Geleijnse JM, Drenos F, Beekman M, Jukema JW, van Duijn CM, Slagboom PE | 2019-08-20 | Nature communications | |
| Perspectives of Healthcare Professionals on Meaningful Activities for Persons with Dementia in Transition from Home to a Nursing Home: An Explorative Study. | Groenendaal M, Loor A, Trouw M, Achterberg WP, Caljouw MAA | 2019-08-19 | dementia, meaningful activities, nursing home, transition | Healthcare (Basel, Switzerland) |
| A meta-analysis of genome-wide association studies identifies multiple longevity genes. | Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X, Wojczynski MK, Biggs ML, van der Spek A, Atzmon G, Ware EB, Sarnowski C, Smith AV, Seppälä I, Cordell HJ, Dose J, Amin N, Arnold AM, Ayers KL, Barzilai N, Becker EJ, Beekman M, Blanché H, Christensen K, Christiansen L, Collerton JC, Cubaynes S, Cummings SR, Davies K, Debrabant B, Deleuze JF, Duncan R, Faul JD, Franceschi C, Galan P, Gudnason V, Harris TB, Huisman M, Hurme MA, Jagger C, Jansen I, Jylhä M, Kähönen M, Karasik D, Kardia SLR, Kingston A, Kirkwood TBL, Launer LJ, Lehtimäki T, Lieb W, Lyytikäinen LP, Martin-Ruiz C, Min J, Nebel A, Newman AB, Nie C, Nohr EA, Orwoll ES, Perls TT, Province MA, Psaty BM, Raitakari OT, Reinders MJT, Robine JM, Rotter JI, Sebastiani P, Smith J, Sørensen TIA, Taylor KD, Uitterlinden AG, van der Flier W, van der Lee SJ, van Duijn CM, van Heemst D, Vaupel JW, Weir D, Ye K, Zeng Y, Zheng W, Holstege H, Kiel DP, Lunetta KL, Slagboom PE, Murabito JM | 2019-08-14 | Nature communications | |
| Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium. | van der Spek A, Broer L, Draisma HHM, Pool R, Albrecht E, Beekman M, Mangino M, Raag M, Nyholt DR, Dharuri HK, Codd V, Amin N, de Geus EJC, Deelen J, Demirkan A, Yet I, Fischer K, Haller T, Henders AK, Isaacs A, Medland SE, Montgomery GW, Mooijaart SP, Strauch K, Suchiman HED, Vaarhorst AAM, van Heemst D, Wang-Sattler R, Whitfield JB, Willemsen G, Wright MJ, Martin NG, Samani NJ, Metspalu A, Eline Slagboom P, Spector TD, Boomsma DI, van Duijn CM, Gieger C | 2019-08-12 | Scientific reports | |
| The association between frailty and MRI features of cerebral small vessel disease. | Kant IMJ, Mutsaerts HJMM, van Montfort SJT, Jaarsma-Coes MG, Witkamp TD, Winterer G, Spies CD, Hendrikse J, Slooter AJC, de Bresser J | 2019-08-05 | Scientific reports | |
| Author Correction: L1 drives IFN in senescent cells and promotes age-associated inflammation. | De Cecco M, Ito T, Petrashen AP, Elias AE, Skvir NJ, Criscione SW, Caligiana A, Brocculi G, Adney EM, Boeke JD, Le O, Beauséjour C, Ambati J, Ambati K, Simon M, Seluanov A, Gorbunova V, Slagboom PE, Helfand SL, Neretti N, Sedivy JM | 2019-08-01 | Nature | |
| Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. | Watson HJ, Yilmaz Z, Thornton LM, Hübel C, Coleman JRI, Gaspar HA, Bryois J, Hinney A, Leppä VM, Mattheisen M, Medland SE, Ripke S, Yao S, Giusti-Rodríguez P, Hanscombe KB, Purves KL, Adan RAH, Alfredsson L, Ando T, Andreassen OA, Baker JH, Berrettini WH, Boehm I, Boni C, Perica VB, Buehren K, Burghardt R, Cassina M, Cichon S, Clementi M, Cone RD, Courtet P, Crow S, Crowley JJ, Danner UN, Davis OSP, de Zwaan M, Dedoussis G, Degortes D, DeSocio JE, Dick DM, Dikeos D, Dina C, Dmitrzak-Weglarz M, Docampo E, Duncan LE, Egberts K, Ehrlich S, Escaramís G, Esko T, Estivill X, Farmer A, Favaro A, Fernández-Aranda F, Fichter MM, Fischer K, Föcker M, Foretova L, Forstner AJ, Forzan M, Franklin CS, Gallinger S, Giegling I, Giuranna J, Gonidakis F, Gorwood P, Mayora MG, Guillaume S, Guo Y, Hakonarson H, Hatzikotoulas K, Hauser J, Hebebrand J, Helder SG, Herms S, Herpertz-Dahlmann B, Herzog W, Huckins LM, Hudson JI, Imgart H, Inoko H, Janout V, Jiménez-Murcia S, Julià A, Kalsi G, Kaminská D, Kaprio J, Karhunen L, Karwautz A, Kas MJH, Kennedy JL, Keski-Rahkonen A, Kiezebrink K, Kim YR, Klareskog L, Klump KL, Knudsen GPS, La Via MC, Le Hellard S, Levitan RD, Li D, Lilenfeld L, Lin BD, Lissowska J, Luykx J, Magistretti PJ, Maj M, Mannik K, Marsal S, Marshall CR, Mattingsdal M, McDevitt S, McGuffin P, Metspalu A, Meulenbelt I, Micali N, Mitchell K, Monteleone AM, Monteleone P, Munn-Chernoff MA, Nacmias B, Navratilova M, Ntalla I, O'Toole JK, Ophoff RA, Padyukov L, Palotie A, Pantel J, Papezova H, Pinto D, Rabionet R, Raevuori A, Ramoz N, Reichborn-Kjennerud T, Ricca V, Ripatti S, Ritschel F, Roberts M, Rotondo A, Rujescu D, Rybakowski F, Santonastaso P, Scherag A, Scherer SW, Schmidt U, Schork NJ, Schosser A, Seitz J, Slachtova L, Slagboom PE, Slof-Op 't Landt MCT, Slopien A, Sorbi S, Świątkowska B, Szatkiewicz JP, Tachmazidou I, Tenconi E, Tortorella A, Tozzi F, Treasure J, Tsitsika A, Tyszkiewicz-Nwafor M, Tziouvas K, van Elburg AA, van Furth EF, Wagner G, Walton E, Widen E, Zeggini E, Zerwas S, Zipfel S, Bergen AW, Boden JM, Brandt H, Crawford S, Halmi KA, Horwood LJ, Johnson C, Kaplan AS, Kaye WH, Mitchell JE, Olsen CM, Pearson JF, Pedersen NL, Strober M, Werge T, Whiteman DC, Woodside DB, Stuber GD, Gordon S, Grove J, Henders AK, Juréus A, Kirk KM, Larsen JT, Parker R, Petersen L, Jordan J, Kennedy M, Montgomery GW, Wade TD, Birgegård A, Lichtenstein P, Norring C, Landén M, Martin NG, Mortensen PB, Sullivan PF, Breen G, Bulik CM | 2019-08-01 | Nature genetics | |
| Associations of sleep duration and quality with serum and hepatic lipids: The Netherlands Epidemiology of Obesity Study. | Bos MM, Noordam R, van den Berg R, de Mutsert R, Rosendaal FR, Blauw GJ, Rensen PCN, Biermasz NR, van Heemst D | 2019-08-01 | cardiovascular diseases, lifestyle, lipids, obesity, sleep | Journal of sleep research |
| Are skin senescence and immunosenescence linked within individuals? | Waaijer MEC, Goldeck D, Gunn DA, van Heemst D, Westendorp RGJ, Pawelec G, Maier AB | 2019-08-01 | cellular senescence, human, immunosenescence, skin aging | Aging cell |
| Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression. | van der Plaat DA, Vonk JM, Terzikhan N, de Jong K, de Vries M, La Bastide-van Gemert S, van Diemen CC, Lahousse L, Brusselle GG, Nedeljkovic I, Amin N, Kromhout H, Vermeulen RCH, Postma DS, van Duijn CM, Boezen HM | 2019-08-01 | Human molecular genetics | |
| Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals. | Mandaviya PR, Joehanes R, Brody J, Castillo-Fernandez JE, Dekkers KF, Do AN, Graff M, Hänninen IK, Tanaka T, de Jonge EAL, Kiefte-de Jong JC, Absher DM, Aslibekyan S, de Rijke YB, Fornage M, Hernandez DG, Hurme MA, Ikram MA, Jacques PF, Justice AE, Kiel DP, Lemaitre RN, Mendelson MM, Mikkilä V, Moore AZ, Pallister T, Raitakari OT, Schalkwijk CG, Sha J, Slagboom EPE, Smith CE, Stehouwer CDA, Tsai PC, Uitterlinden AG, van der Kallen CJH, van Heemst D, Arnett DK, Bandinelli S, Bell JT, Heijmans BT, Lehtimäki T, Levy D, North KE, Sotoodehnia N, van Greevenbroek MMJ, van Meurs JBJ, Heil SG | 2019-08-01 | DNA methylation, Epigenome-wide Association Study, FFQ, diet, epigenetics, folate, genome-wide, vitamin B-12 | The American journal of clinical nutrition |
| Comparing Methods for Measurement Error Detection in Serial 24-h Hormonal Data. | van der Spoel E, Choi J, Roelfsema F, Cessie SL, van Heemst D, Dekkers OM | 2019-08-01 | automatic outlier detection, hormones, measurement error, outlier, time series | Journal of biological rhythms |
| BMI-associated gene variants in FTO and cardiometabolic and brain disease: obesity or pleiotropy? | Ganeff IMM, Bos MM, van Heemst D, Noordam R | 2019-08-01 | brain disease, cardiometabolic disease, obesity, pleiotropy | Physiological genomics |
| The impact of reclassifying suicides in pregnancy and in the postnatal period on maternal mortality ratios. | Lommerse K, Knight M, Nair M, Deneux-Tharaux C, van den Akker T | 2019-08-01 | BJOG : an international journal of obstetrics and gynaecology | |
| Lessons learnt from anonymized review of cases of peripartum hysterectomy by international experts: A qualitative pilot study. | Jónasdóttir E, Aabakke AJM, Colmorn LB, Jakobsson M, Äyräs O, Baghestan E, Svanvik T, van den Akker T, Bloemenkamp K, van Roosmalen J, Krebs L, Knight M, Langhoff-Roos J | 2019-08-01 | case narrative, maternity care, obstetric complications, peripartum hysterectomy, qualitative audit | Acta obstetricia et gynecologica Scandinavica |
| Maternal and perinatal outcomes of asylum seekers and undocumented migrants in Europe: a systematic review. | Gieles NC, Tankink JB, van Midde M, Düker J, van der Lans P, Wessels CM, Bloemenkamp KWM, Bonsel G, van den Akker T, Goosen S, Rijken MJ, Browne JL | 2019-08-01 | European journal of public health | |
| Determinants of self-rated health in older adults before and 3 months after an emergency department visit: a prospective study. | Van Deudekom FJ, De Gelder J, Lucke JA, Oostendorp-Lange A, Anten S, Blauw GJ, De Groot B, Mooijaart SP | 2019-08-01 | European journal of emergency medicine : official journal of the European Society for Emergency Medicine | |
| Geriatric assessment and 1-year mortality in older patients with cancer in the head and neck region: A cohort study. | van Deudekom FJ, van der Velden LA, Zijl WH, Schimberg AS, Langeveld AP, Slingerland M, Blauw GJ, Mooijaart SP | 2019-08-01 | cognitive disorders, geriatric oncology, head and neck cancer, physical functioning, social functioning | Head & neck |
| Subclinical thyroid dysfunction and depressive symptoms: protocol for a systematic review and individual participant data meta-analysis of prospective cohort studies. | Wildisen L, Moutzouri E, Beglinger S, Syrogiannouli L, Cappola AR, Åsvold BO, Bakker SJL, Ceresini G, Dullaart R, Ferrucci L, Grabe H, Jukema JW, Nauck M, Trompet S, Völzke H, Westendorp RGJ, Gussekloo J, Peeters RP, Klöppel S, Aujesky D, Bauer DC, Rodondi N, Del Giovane C, Feller M | 2019-07-26 | depressive symptoms, individual participant data (IPD) meta-analysis, subclinical hyperthyroidism, subclinical hypothyroidism, subclinical thyroid dysfunction, systematic review | BMJ open |
| Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits. | Porcu E, Rüeger S, Lepik K, Santoni FA, Reymond A, Kutalik Z | 2019-07-24 | Nature communications | |
| Caffeine and neuropsychiatric symptoms in patients with dementia: A systematic review. | Kromhout MA, Rius Ottenheim N, Giltay E, Numans ME, Achterberg WP | 2019-07-15 | Behavior, Caffeine, Dementia, Neuropsychiatric symptoms, Sleep | Experimental gerontology |
| Associations of Outdoor Temperature, Bright Sunlight, and Cardiometabolic Traits in Two European Population-Based Cohorts. | Noordam R, Ramkisoensing A, Loh NY, Neville MJ, Rosendaal FR, Willems van Dijk K, van Heemst D, Karpe F, Christodoulides C, Kooijman S | 2019-07-01 | The Journal of clinical endocrinology and metabolism | |
| Physiological-based cord clamping in preterm infants using a new purpose-built resuscitation table: a feasibility study. | Brouwer E, Knol R, Vernooij ASN, van den Akker T, Vlasman PE, Klumper FJCM, DeKoninck P, Polglase GR, Hooper SB, Te Pas AB | 2019-07-01 | circulatory, neonatology, physiology, respiratory, resuscitation | Archives of disease in childhood. Fetal and neonatal edition |
| A district-wide population-based descriptive study of emergency peripartum hysterectomy in a middle-income country. | Heitkamp A, Seinstra J, van den Akker T, Vollmer L, Gebhardt S, van Roosmalen J, de Vries JI, Theron G | 2019-07-01 | Emergency peripartum hysterectomy, High-risk pregnancy, Maternal mortality, Maternal near miss, Maternal sepsis, Obstetric surgery, Postpartum hemorrhage, Quality of obstetric care | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics |
| A Prospective Cohort Study on the Effects of Geriatric Rehabilitation Following Acute Exacerbations of COPD. | van Dam van Isselt EF, van Eijk M, van Geloven N, Groenewegen-Sipkema KH, van den Berg JK, Nieuwenhuys CMA, Chavannes NH, Achterberg WP | 2019-07-01 | COPD, Geriatric rehabilitation, health status, post-acute PR, propensity score | Journal of the American Medical Directors Association |
| Effects of the FIT-HIP Intervention for Fear of Falling After Hip Fracture: A Cluster-Randomized Controlled Trial in Geriatric Rehabilitation. | Scheffers-Barnhoorn MN, van Eijk M, van Haastregt JCM, Schols JMGA, van Balen R, van Geloven N, Kempen GIJM, Achterberg WP | 2019-07-01 | Fear of falling, cognitive behavioral therapy, geriatric rehabilitation, hip fracture, randomized controlled trial | Journal of the American Medical Directors Association |
| Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals. | Noordam R, Young WJ, Salman R, Kanters JK, van den Berg ME, van Heemst D, Lin HJ, Barreto SM, Biggs ML, Biino G, Catamo E, Concas MP, Ding J, Evans DS, Foco L, Grarup N, Lyytikäinen LP, Mangino M, Mei H, van der Most PJ, Müller-Nurasyid M, Nelson CP, Qian Y, Repetto L, Said MA, Shah N, Schramm K, Vidigal PG, Weiss S, Yao J, Zilhao NR, Brody JA, Braund PS, Brumat M, Campana E, Christofidou P, Caulfield MJ, De Grandi A, Dominiczak AF, Doney ASF, Eiriksdottir G, Ellervik C, Giatti L, Gögele M, Graff C, Guo X, van der Harst P, Joshi PK, Kähönen M, Kestenbaum B, Lima-Costa MF, Linneberg A, Maan AC, Meitinger T, Padmanabhan S, Pattaro C, Peters A, Petersmann A, Sever P, Sinner MF, Shen X, Stanton A, Strauch K, Soliman EZ, Tarasov KV, Taylor KD, Thio CHL, Uitterlinden AG, Vaccargiu S, Waldenberger M, Robino A, Correa A, Cucca F, Cummings SR, Dörr M, Girotto G, Gudnason V, Hansen T, Heckbert SR, Juhl CR, Kääb S, Lehtimäki T, Liu Y, Lotufo PA, Palmer CNA, Pirastu M, Pramstaller PP, Ribeiro ALP, Rotter JI, Samani NJ, Snieder H, Spector TD, Stricker BH, Verweij N, Wilson JF, Wilson JG, Jukema JW, Tinker A, Newton-Cheh CH, Sotoodehnia N, Mook-Kanamori DO, Munroe PB, Warren HR | 2019-06-25 | cohort studies, electrocardiographic intervals, electrolytes, epidemiology, meta-analysis | Journal of the American College of Cardiology |
| Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk. | Kurilshikov A, van den Munckhof ICL, Chen L, Bonder MJ, Schraa K, Rutten JHW, Riksen NP, de Graaf J, Oosting M, Sanna S, Joosten LAB, van der Graaf M, Brand T, Koonen DPY, van Faassen M, Slagboom PE, Xavier RJ, Kuipers F, Hofker MH, Wijmenga C, Netea MG, Zhernakova A, Fu J | 2019-06-07 | atherosclerosis, inflammation, metabolomics, metagenomics, microbiota | Circulation research |
| Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. | de Vries PS, Brown MR, Bentley AR, Sung YJ, Winkler TW, Ntalla I, Schwander K, Kraja AT, Guo X, Franceschini N, Cheng CY, Sim X, Vojinovic D, Huffman JE, Musani SK, Li C, Feitosa MF, Richard MA, Noordam R, Aschard H, Bartz TM, Bielak LF, Deng X, Dorajoo R, Lohman KK, Manning AK, Rankinen T, Smith AV, Tajuddin SM, Evangelou E, Graff M, Alver M, Boissel M, Chai JF, Chen X, Divers J, Gandin I, Gao C, Goel A, Hagemeijer Y, Harris SE, Hartwig FP, He M, Horimoto ARVR, Hsu FC, Jackson AU, Kasturiratne A, Komulainen P, Kühnel B, Laguzzi F, Lee JH, Luan J, Lyytikäinen LP, Matoba N, Nolte IM, Pietzner M, Riaz M, Said MA, Scott RA, Sofer T, Stančáková A, Takeuchi F, Tayo BO, van der Most PJ, Varga TV, Wang Y, Ware EB, Wen W, Yanek LR, Zhang W, Zhao JH, Afaq S, Amin N, Amini M, Arking DE, Aung T, Ballantyne C, Boerwinkle E, Broeckel U, Campbell A, Canouil M, Charumathi S, Chen YI, Connell JM, de Faire U, de Las Fuentes L, de Mutsert R, de Silva HJ, Ding J, Dominiczak AF, Duan Q, Eaton CB, Eppinga RN, Faul JD, Fisher V, Forrester T, Franco OH, Friedlander Y, Ghanbari M, Giulianini F, Grabe HJ, Grove ML, Gu CC, Harris TB, Heikkinen S, Heng CK, Hirata M, Hixson JE, Howard BV, Ikram MA, Jacobs DR, Johnson C, Jonas JB, Kammerer CM, Katsuya T, Khor CC, Kilpeläinen TO, Koh WP, Koistinen HA, Kolcic I, Kooperberg C, Krieger JE, Kritchevsky SB, Kubo M, Kuusisto J, Lakka TA, Langefeld CD, Langenberg C, Launer LJ, Lehne B, Lemaitre RN, Li Y, Liang J, Liu J, Liu K, Loh M, Louie T, Mägi R, Manichaikul AW, McKenzie CA, Meitinger T, Metspalu A, Milaneschi Y, Milani L, Mohlke KL, Mosley TH, Mukamal KJ, Nalls MA, Nauck M, Nelson CP, Sotoodehnia N, O'Connell JR, Palmer ND, Pazoki R, Pedersen NL, Peters A, Peyser PA, Polasek O, Poulter N, Raffel LJ, Raitakari OT, Reiner AP, Rice TK, Rich SS, Robino A, Robinson JG, Rose LM, Rudan I, Schmidt CO, Schreiner PJ, Scott WR, Sever P, Shi Y, Sidney S, Sims M, Smith BH, Smith JA, Snieder H, Starr JM, Strauch K, Tan N, Taylor KD, Teo YY, Tham YC, Uitterlinden AG, van Heemst D, Vuckovic D, Waldenberger M, Wang L, Wang Y, Wang Z, Wei WB, Williams C, Wilson G, Wojczynski MK, Yao J, Yu B, Yu C, Yuan JM, Zhao W, Zonderman AB, Becker DM, Boehnke M, Bowden DW, Chambers JC, Deary IJ, Esko T, Farrall M, Franks PW, Freedman BI, Froguel P, Gasparini P, Gieger C, Horta BL, Kamatani Y, Kato N, Kooner JS, Laakso M, Leander K, Lehtimäki T, Magnusson PKE, Penninx B, Pereira AC, Rauramaa R, Samani NJ, Scott J, Shu XO, van der Harst P, Wagenknecht LE, Wang YX, Wareham NJ, Watkins H, Weir DR, Wickremasinghe AR, Zheng W, Elliott P, North KE, Bouchard C, Evans MK, Gudnason V, Liu CT, Liu Y, Psaty BM, Ridker PM, van Dam RM, Kardia SLR, Zhu X, Rotimi CN, Mook-Kanamori DO, Fornage M, Kelly TN, Fox ER, Hayward C, van Duijn CM, Tai ES, Wong TY, Liu J, Rotter JI, Gauderman WJ, Province MA, Munroe PB, Rice K, Chasman DI, Cupples LA, Rao DC, Morrison AC | 2019-06-01 | alcohol consumption, cholesterol, gene-environment interactions, gene-lifestyle interactions, genome-wide association studies, lipids, triglycerides | American journal of epidemiology |
| Women receiving massive transfusion due to postpartum hemorrhage: A comparison over time between two nationwide cohort studies. | Ramler PI, van den Akker T, Henriquez DDCA, Zwart JJ, van Roosmalen J, van Lith JMM, van der Bom JG | 2019-06-01 | blood transfusion, hysterectomy, morbidity, mortality, postpartum hemorrhage | Acta obstetricia et gynecologica Scandinavica |
| Maternal cardiac arrest in the Netherlands: A nationwide surveillance study. | Schaap TP, Overtoom E, van den Akker T, Zwart JJ, van Roosmalen J, Bloemenkamp KWM | 2019-06-01 | Cardiac arrest, Maternal morbidity, Perimortem CS | European journal of obstetrics, gynecology, and reproductive biology |
| Is Prolonged Labor Managed Adequately in Rural Rwandan Hospitals? | Kalisa R, Rulisa S, van den Akker T, van Roosmalen J | 2019-06-01 | Cesarean section, oxytocin, partograph, prolonged labor, vacuum extraction | African journal of reproductive health |
| Prevalence of Carriers of Intermediate and Pathological Polyglutamine Disease-Associated Alleles Among Large Population-Based Cohorts. | Gardiner SL, Boogaard MW, Trompet S, de Mutsert R, Rosendaal FR, Gussekloo J, Jukema JW, Roos RAC, Aziz NA | 2019-06-01 | JAMA neurology | |
| The Association between Habitual Sleep Duration and Sleep Quality with Glycemic Traits: Assessment by Cross-Sectional and Mendelian Randomization Analyses. | Bos MM, van Heemst D, Donga E, de Mutsert R, Rosendaal FR, Blauw GJ, Rensen PCN, Biermasz NR, Noordam R | 2019-05-15 | diabetes, epidemiology, insulin resistance, mendelian randomization, sleep | Journal of clinical medicine |
| Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. | Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C, Hofer E, Ikram MA, Karlsson R, Knowles E, Lahti J, Leber M, Li S, Mather KA, Melle I, Morris D, Oldmeadow C, Palviainen T, Payton A, Pazoki R, Petrovic K, Reynolds CA, Sargurupremraj M, Scholz M, Smith JA, Smith AV, Terzikhan N, Thalamuthu A, Trompet S, van der Lee SJ, Ware EB, Windham BG, Wright MJ, Yang J, Yu J, Ames D, Amin N, Amouyel P, Andreassen OA, Armstrong NJ, Assareh AA, Attia JR, Attix D, Avramopoulos D, Bennett DA, Böhmer AC, Boyle PA, Brodaty H, Campbell H, Cannon TD, Cirulli ET, Congdon E, Conley ED, Corley J, Cox SR, Dale AM, Dehghan A, Dick D, Dickinson D, Eriksson JG, Evangelou E, Faul JD, Ford I, Freimer NA, Gao H, Giegling I, Gillespie NA, Gordon SD, Gottesman RF, Griswold ME, Gudnason V, Harris TB, Hartmann AM, Hatzimanolis A, Heiss G, Holliday EG, Joshi PK, Kähönen M, Kardia SLR, Karlsson I, Kleineidam L, Knopman DS, Kochan NA, Konte B, Kwok JB, Le Hellard S, Lee T, Lehtimäki T, Li SC, Lill CM, Liu T, Koini M, London E, Longstreth WT, Lopez OL, Loukola A, Luck T, Lundervold AJ, Lundquist A, Lyytikäinen LP, Martin NG, Montgomery GW, Murray AD, Need AC, Noordam R, Nyberg L, Ollier W, Papenberg G, Pattie A, Polasek O, Poldrack RA, Psaty BM, Reppermund S, Riedel-Heller SG, Rose RJ, Rotter JI, Roussos P, Rovio SP, Saba Y, Sabb FW, Sachdev PS, Satizabal CL, Schmid M, Scott RJ, Scult MA, Simino J, Slagboom PE, Smyrnis N, Soumaré A, Stefanis NC, Stott DJ, Straub RE, Sundet K, Taylor AM, Taylor KD, Tzoulaki I, Tzourio C, Uitterlinden A, Vitart V, Voineskos AN, Kaprio J, Wagner M, Wagner H, Weinhold L, Wen KH, Widen E, Yang Q, Zhao W, Adams HHH, Arking DE, Bilder RM, Bitsios P, Boerwinkle E, Chiba-Falek O, Corvin A, De Jager PL, Debette S, Donohoe G, Elliott P, Fitzpatrick AL, Gill M, Glahn DC, Hägg S, Hansell NK, Hariri AR, Ikram MK, Jukema JW, Vuoksimaa E, Keller MC, Kremen WS, Launer L, Lindenberger U, Palotie A, Pedersen NL, Pendleton N, Porteous DJ, Räikkönen K, Raitakari OT, Ramirez A, Reinvang I, Rudan I, Dan Rujescu, Schmidt R, Schmidt H, Schofield PW, Schofield PR, Starr JM, Steen VM, Trollor JN, Turner ST, Van Duijn CM, Villringer A, Weinberger DR, Weir DR, Wilson JF, Malhotra A, McIntosh AM, Gale CR, Seshadri S, Mosley TH, Bressler J, Lencz T, Deary IJ | 2019-05-01 | Nature communications | |
| Women’s recommendations: vacuum extraction or caesarean section for prolonged second stage of labour, a prospective cohort study in Uganda. | Nolens B, van den Akker T, Lule J, Twinomuhangi S, van Roosmalen J, Byamugisha J | 2019-05-01 | accouchement, caesarean section, césarienne obstétricale, delivery, extraction sous vide, low- and middle-income countries, obstétrique, pays à revenu faible ou intermédiaire, préférences des femmes, vacuum extraction, women's preferences | Tropical medicine & international health : TM & IH |
| Absence of the Association of Blood Pressure With Age in a Remote Venezuelan Population Renews the Call for Population-Wide Interventions. | Schalkwijk FH, van Bodegom D | 2019-05-01 | JAMA cardiology | |
| Effects of a clinical medication review focused on personal goals, quality of life, and health problems in older persons with polypharmacy: A randomised controlled trial (DREAMeR-study). | Verdoorn S, Kwint HF, Blom JW, Gussekloo J, Bouvy ML | 2019-05-01 | PLoS medicine | |
| Longitudinal assessment of the Unified Huntington’s Disease Rating Scale (UHDRS) and UHDRS-For Advanced Patients (UHDRS-FAP) in patients with late stage Huntington’s disease. | Winder JY, Achterberg WP, Gardiner SL, Roos RAC | 2019-05-01 | Huntington's disease, advanced stage, long-term care facility, longitudinal analysis, rating scales | European journal of neurology |
| Psychosis symptoms in nursing home residents with and without dementia-Cross-sectional analyses from the COSMOS study. | Habiger TF, Achterberg WP, Flo E, Husebo BS | 2019-05-01 | dementia, neuropsychiatric symptoms, nursing home, pain, psychosis, psychotropic drugs, quality of life | International journal of geriatric psychiatry |
| Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine. | Onderwater GLJ, Ligthart L, Bot M, Demirkan A, Fu J, van der Kallen CJH, Vijfhuizen LS, Pool R, Liu J, Vanmolkot FHM, Beekman M, Wen KX, Amin N, Thesing CS, Pijpers JA, Kies DA, Zielman R, de Boer I, van Greevenbroek MMJ, Arts ICW, Milaneschi Y, Schram MT, Dagnelie PC, Franke L, Ikram MA, Ferrari MD, Goeman JJ, Slagboom PE, Wijmenga C, Stehouwer CDA, Boomsma DI, van Duijn CM, Penninx BW, 't Hoen PAC, Terwindt GM, van den Maagdenberg AMJM | 2019-04-16 | Neurology | |
| Clinical relevance of acute cerebral microinfarcts in vascular cognitive impairment. | Ferro DA, van den Brink H, Exalto LG, Boomsma JMF, Barkhof F, Prins ND, van der Flier WM, Biessels GJ | 2019-04-02 | Neurology | |
| Adult weight change in relation to visceral fat and liver fat at middle age: The Netherlands epidemiology of obesity study. | Verkouter I, Noordam R, de Roos A, Lamb HJ, Rosendaal FR, van Heemst D, de Mutsert R | 2019-04-01 | International journal of obesity (2005) | |
| Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. | Bentley AR, Sung YJ, Brown MR, Winkler TW, Kraja AT, Ntalla I, Schwander K, Chasman DI, Lim E, Deng X, Guo X, Liu J, Lu Y, Cheng CY, Sim X, Vojinovic D, Huffman JE, Musani SK, Li C, Feitosa MF, Richard MA, Noordam R, Baker J, Chen G, Aschard H, Bartz TM, Ding J, Dorajoo R, Manning AK, Rankinen T, Smith AV, Tajuddin SM, Zhao W, Graff M, Alver M, Boissel M, Chai JF, Chen X, Divers J, Evangelou E, Gao C, Goel A, Hagemeijer Y, Harris SE, Hartwig FP, He M, Horimoto ARVR, Hsu FC, Hung YJ, Jackson AU, Kasturiratne A, Komulainen P, Kühnel B, Leander K, Lin KH, Luan J, Lyytikäinen LP, Matoba N, Nolte IM, Pietzner M, Prins B, Riaz M, Robino A, Said MA, Schupf N, Scott RA, Sofer T, Stancáková A, Takeuchi F, Tayo BO, van der Most PJ, Varga TV, Wang TD, Wang Y, Ware EB, Wen W, Xiang YB, Yanek LR, Zhang W, Zhao JH, Adeyemo A, Afaq S, Amin N, Amini M, Arking DE, Arzumanyan Z, Aung T, Ballantyne C, Barr RG, Bielak LF, Boerwinkle E, Bottinger EP, Broeckel U, Brown M, Cade BE, Campbell A, Canouil M, Charumathi S, Chen YI, Christensen K, Concas MP, Connell JM, de Las Fuentes L, de Silva HJ, de Vries PS, Doumatey A, Duan Q, Eaton CB, Eppinga RN, Faul JD, Floyd JS, Forouhi NG, Forrester T, Friedlander Y, Gandin I, Gao H, Ghanbari M, Gharib SA, Gigante B, Giulianini F, Grabe HJ, Gu CC, Harris TB, Heikkinen S, Heng CK, Hirata M, Hixson JE, Ikram MA, Jia Y, Joehanes R, Johnson C, Jonas JB, Justice AE, Katsuya T, Khor CC, Kilpeläinen TO, Koh WP, Kolcic I, Kooperberg C, Krieger JE, Kritchevsky SB, Kubo M, Kuusisto J, Lakka TA, Langefeld CD, Langenberg C, Launer LJ, Lehne B, Lewis CE, Li Y, Liang J, Lin S, Liu CT, Liu J, Liu K, Loh M, Lohman KK, Louie T, Luzzi A, Mägi R, Mahajan A, Manichaikul AW, McKenzie CA, Meitinger T, Metspalu A, Milaneschi Y, Milani L, Mohlke KL, Momozawa Y, Morris AP, Murray AD, Nalls MA, Nauck M, Nelson CP, North KE, O'Connell JR, Palmer ND, Papanicolau GJ, Pedersen NL, Peters A, Peyser PA, Polasek O, Poulter N, Raitakari OT, Reiner AP, Renström F, Rice TK, Rich SS, Robinson JG, Rose LM, Rosendaal FR, Rudan I, Schmidt CO, Schreiner PJ, Scott WR, Sever P, Shi Y, Sidney S, Sims M, Smith JA, Snieder H, Starr JM, Strauch K, Stringham HM, Tan NYQ, Tang H, Taylor KD, Teo YY, Tham YC, Tiemeier H, Turner ST, Uitterlinden AG, van Heemst D, Waldenberger M, Wang H, Wang L, Wang L, Wei WB, Williams CA, Wilson G, Wojczynski MK, Yao J, Young K, Yu C, Yuan JM, Zhou J, Zonderman AB, Becker DM, Boehnke M, Bowden DW, Chambers JC, Cooper RS, de Faire U, Deary IJ, Elliott P, Esko T, Farrall M, Franks PW, Freedman BI, Froguel P, Gasparini P, Gieger C, Horta BL, Juang JJ, Kamatani Y, Kammerer CM, Kato N, Kooner JS, Laakso M, Laurie CC, Lee IT, Lehtimäki T, Magnusson PKE, Oldehinkel AJ, Penninx BWJH, Pereira AC, Rauramaa R, Redline S, Samani NJ, Scott J, Shu XO, van der Harst P, Wagenknecht LE, Wang JS, Wang YX, Wareham NJ, Watkins H, Weir DR, Wickremasinghe AR, Wu T, Zeggini E, Zheng W, Bouchard C, Evans MK, Gudnason V, Kardia SLR, Liu Y, Psaty BM, Ridker PM, van Dam RM, Mook-Kanamori DO, Fornage M, Province MA, Kelly TN, Fox ER, Hayward C, van Duijn CM, Tai ES, Wong TY, Loos RJF, Franceschini N, Rotter JI, Zhu X, Bierut LJ, Gauderman WJ, Rice K, Munroe PB, Morrison AC, Rao DC, Rotimi CN, Cupples LA | 2019-04-01 | Nature genetics | |
| Vacuum extraction for non-rotational and rotational assisted vaginal birth. | van den Akker T | 2019-04-01 | Labour stage, Obstetrical, Obstetrics, Pregnancy, Second, Vacuum extraction | Best practice & research. Clinical obstetrics & gynaecology |
| Use of assisted vaginal birth to reduce unnecessary caesarean sections and improve maternal and perinatal outcomes. | Nolens B, Capelle M, van Roosmalen J, Mola G, Byamugisha J, Lule J, Faye A, van den Akker T | 2019-04-01 | The Lancet. Global health | |
| Predictive value of a bleeding score for postpartum hemorrhage. | Gillissen A, van den Akker T, Caram-Deelder C, Henriquez DDCA, Nij Bijvank SWA, Bloemenkamp KWM, Eikenboom J, van der Bom JG | 2019-04-01 | bleeding assessment tool, bleeding score, postpartum hemorrhage, prediction, pregnancy | Research and practice in thrombosis and haemostasis |
| Geriatric emergency medicine: time for a new approach on a European level. | Mooijaart SP, Lucke JA, Brabrand M, Conroy S, Nickel CH | 2019-04-01 | European journal of emergency medicine : official journal of the European Society for Emergency Medicine | |
| Low thyroid function is not associated with an accelerated deterioration in renal function. | Meuwese CL, van Diepen M, Cappola AR, Sarnak MJ, Shlipak MG, Bauer DC, Fried LP, Iacoviello M, Vaes B, Degryse J, Khaw KT, Luben RN, Åsvold BO, Bjøro T, Vatten LJ, de Craen AJM, Trompet S, Iervasi G, Molinaro S, Ceresini G, Ferrucci L, Dullaart RPF, Bakker SJL, Jukema JW, Kearney PM, Stott DJ, Peeters RP, Franco OH, Völzke H, Walsh JP, Bremner A, Sgarbi JA, Maciel RMB, Imaizumi M, Ohishi W, Dekker FW, Rodondi N, Gussekloo J, den Elzen WPJ | 2019-04-01 | CKD, chronic renal failure, creatinine clearance, epidemiology, thyroid function | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association |
| The prevalence and the burden of pain in patients with Huntington disease: a systematic review and meta-analysis. | Sprenger GP, van der Zwaan KF, Roos RAC, Achterberg WP | 2019-04-01 | Pain | |
| Geriatric Rehabilitation-State of the Art and Future Priorities. | Achterberg WP, Cameron ID, Bauer JM, Schols JM | 2019-04-01 | Journal of the American Medical Directors Association | |
| Repeat length variations in polyglutamine disease-associated genes affect body mass index. | Gardiner SL, de Mutsert R, Trompet S, Boogaard MW, van Dijk KW, Jukema PJW, Slagboom PE, Roos RAC, Pijl H, Rosendaal FR, Aziz NA | 2019-03-01 | International journal of obesity (2005) | |
| The 24-hour serum profiles of bone markers in healthy older men and women. | van der Spoel E, Oei N, Cachucho R, Roelfsema F, Berbée JFP, Blauw GJ, Pijl H, Appelman-Dijkstra NM, van Heemst D | 2019-03-01 | 24-hour profile, Bone markers, Circadian rhythm, Cosinor analysis, Sex differences | Bone |
| Mendelian randomization reveals unexpected effects of CETP on the lipoprotein profile. | Blauw LL, Noordam R, Soidinsalo S, Blauw CA, Li-Gao R, de Mutsert R, Berbée JFP, Wang Y, van Heemst D, Rosendaal FR, Jukema JW, Mook-Kanamori DO, Würtz P, Willems van Dijk K, Rensen PCN | 2019-03-01 | European journal of human genetics : EJHG | |
| Skewed X-inactivation is common in the general female population. | Shvetsova E, Sofronova A, Monajemi R, Gagalova K, Draisma HHM, White SJ, Santen GWE, Chuva de Sousa Lopes SM, Heijmans BT, van Meurs J, Jansen R, Franke L, Kiełbasa SM, den Dunnen JT, 't Hoen PAC | 2019-03-01 | European journal of human genetics : EJHG | |
| A national surveillance approach to monitor incidence of eclampsia: The Netherlands Obstetric Surveillance System. | Schaap TP, van den Akker T, Zwart JJ, van Roosmalen J, Bloemenkamp KWM | 2019-03-01 | INOSS, NethOSS, eclampsia, maternal morbidity, obstetric surveillance system | Acta obstetricia et gynecologica Scandinavica |
| Erythrocyte sedimentation rate as an independent prognostic marker for mortality: a prospective population-based cohort study. | Fest J, Ruiter R, Mooijaart SP, Ikram MA, van Eijck CHJ, Stricker BH | 2019-03-01 | ageing, erythrocyte sedimentation rate, general population, low-grade inflammation, mortality | Journal of internal medicine |
| Systolic Blood Pressure and Cognitive Decline in Older Adults With Hypertension. | Streit S, Poortvliet RKE, Elzen WPJD, Blom JW, Gussekloo J | 2019-03-01 | cognitive function, daily functioning, hypertension, old age, quality of life | Annals of family medicine |
| Applicability of the WHO maternal near miss tool in sub-Saharan Africa: a systematic review. | Tura AK, Trang TL, van den Akker T, van Roosmalen J, Scherjon S, Zwart J, Stekelenburg J | 2019-02-26 | Maternal near miss, Severe acute maternal morbidity, Severe maternal outcomes, Sub-Saharan Africa, Systematic review | BMC pregnancy and childbirth |
| Metabolomic and lipidomic assessment of the metabolic syndrome in Dutch middle-aged individuals reveals novel biological signatures separating health and disease. | Surowiec I, Noordam R, Bennett K, Beekman M, Slagboom PE, Lundstedt T, van Heemst D | 2019-02-12 | Epidemiology, Lipidomics, Metabolic syndrome, Metabolomics | Metabolomics : Official journal of the Metabolomic Society |
| RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage. | Coutinho de Almeida R, Ramos YFM, Mahfouz A, den Hollander W, Lakenberg N, Houtman E, van Hoolwerff M, Suchiman HED, Rodríguez Ruiz A, Slagboom PE, Mei H, Kiełbasa SM, Nelissen RGHH, Reinders M, Meulenbelt I | 2019-02-01 | data integration, mRNA, microRNAs, osteoarthritis, regulatory networks | Annals of the rheumatic diseases |
| L1 drives IFN in senescent cells and promotes age-associated inflammation. | De Cecco M, Ito T, Petrashen AP, Elias AE, Skvir NJ, Criscione SW, Caligiana A, Brocculi G, Adney EM, Boeke JD, Le O, Beauséjour C, Ambati J, Ambati K, Simon M, Seluanov A, Gorbunova V, Slagboom PE, Helfand SL, Neretti N, Sedivy JM | 2019-02-01 | Nature | |
| Defining definitions: a Delphi study to develop a core outcome set for conditions of severe maternal morbidity. | Schaap T, Bloemenkamp K, Deneux-Tharaux C, Knight M, Langhoff-Roos J, Sullivan E, van den Akker T | 2019-02-01 | Abnormally invasive placentation, Delphi, amniotic fluid embolism, cardiac arrest in pregnancy, eclampsia, pregnancy-related hysterectomy, severe acute maternal morbidity, severe primary postpartum haemorrhage, spontaneous hemoperitoneum in pregnancy, uterine rupture | BJOG : an international journal of obstetrics and gynaecology |
| Comparison of thromboelastometry by ROTEM® Delta and ROTEM® Sigma in women with postpartum haemorrhage. | Gillissen A, van den Akker T, Caram-Deelder C, Henriquez DDCA, Bloemenkamp KWM, Eikenboom J, van der Bom JG, de Maat MPM | 2019-02-01 | ROTEM Delta, ROTEM Sigma, Thromboelastometry, comparison, postpartum haemorrhage | Scandinavian journal of clinical and laboratory investigation |
| Acute care assessment of older adults living with frailty. | Quinn TJ, Mooijaart SP, Gallacher K, Burton JK | 2019-01-31 | BMJ (Clinical research ed.) | |
| Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. | Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Guðnason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hernández MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Muñoz Maniega S, Slagboom PE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, Hosten N, von Sarnowski B, Völker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow CLM, Rosand J, Woo D, Cole JW, Meschia JF, Slowik A, Thijs V, Lindgren A, Melander O, Grewal RP, Rundek T, Rexrode K, Rothwell PM, Arnett DK, Jern C, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Wong Q, Mitchell BD, Rich SS, McArdle PF, Geerlings MI, van der Graaf Y, de Bakker PIW, Asselbergs FW, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs LCA, Bevan S, Tzourio C, Mather KA, Sachdev PS, van Duijn CM, Worrall BB, Dichgans M, Kittner SJ, Markus HS, Ikram MA, Fornage M, Launer LJ, Seshadri S, Longstreth WT, Debette S | 2019-01-28 | Neurology | |
| Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. | Kilpeläinen TO, Bentley AR, Noordam R, Sung YJ, Schwander K, Winkler TW, Jakupović H, Chasman DI, Manning A, Ntalla I, Aschard H, Brown MR, de Las Fuentes L, Franceschini N, Guo X, Vojinovic D, Aslibekyan S, Feitosa MF, Kho M, Musani SK, Richard M, Wang H, Wang Z, Bartz TM, Bielak LF, Campbell A, Dorajoo R, Fisher V, Hartwig FP, Horimoto ARVR, Li C, Lohman KK, Marten J, Sim X, Smith AV, Tajuddin SM, Alver M, Amini M, Boissel M, Chai JF, Chen X, Divers J, Evangelou E, Gao C, Graff M, Harris SE, He M, Hsu FC, Jackson AU, Zhao JH, Kraja AT, Kühnel B, Laguzzi F, Lyytikäinen LP, Nolte IM, Rauramaa R, Riaz M, Robino A, Rueedi R, Stringham HM, Takeuchi F, van der Most PJ, Varga TV, Verweij N, Ware EB, Wen W, Li X, Yanek LR, Amin N, Arnett DK, Boerwinkle E, Brumat M, Cade B, Canouil M, Chen YI, Concas MP, Connell J, de Mutsert R, de Silva HJ, de Vries PS, Demirkan A, Ding J, Eaton CB, Faul JD, Friedlander Y, Gabriel KP, Ghanbari M, Giulianini F, Gu CC, Gu D, Harris TB, He J, Heikkinen S, Heng CK, Hunt SC, Ikram MA, Jonas JB, Koh WP, Komulainen P, Krieger JE, Kritchevsky SB, Kutalik Z, Kuusisto J, Langefeld CD, Langenberg C, Launer LJ, Leander K, Lemaitre RN, Lewis CE, Liang J, Liu J, Mägi R, Manichaikul A, Meitinger T, Metspalu A, Milaneschi Y, Mohlke KL, Mosley TH, Murray AD, Nalls MA, Nang EK, Nelson CP, Nona S, Norris JM, Nwuba CV, O'Connell J, Palmer ND, Papanicolau GJ, Pazoki R, Pedersen NL, Peters A, Peyser PA, Polasek O, Porteous DJ, Poveda A, Raitakari OT, Rich SS, Risch N, Robinson JG, Rose LM, Rudan I, Schreiner PJ, Scott RA, Sidney SS, Sims M, Smith JA, Snieder H, Sofer T, Starr JM, Sternfeld B, Strauch K, Tang H, Taylor KD, Tsai MY, Tuomilehto J, Uitterlinden AG, van der Ende MY, van Heemst D, Voortman T, Waldenberger M, Wennberg P, Wilson G, Xiang YB, Yao J, Yu C, Yuan JM, Zhao W, Zonderman AB, Becker DM, Boehnke M, Bowden DW, de Faire U, Deary IJ, Elliott P, Esko T, Freedman BI, Froguel P, Gasparini P, Gieger C, Kato N, Laakso M, Lakka TA, Lehtimäki T, Magnusson PKE, Oldehinkel AJ, Penninx BWJH, Samani NJ, Shu XO, van der Harst P, Van Vliet-Ostaptchouk JV, Vollenweider P, Wagenknecht LE, Wang YX, Wareham NJ, Weir DR, Wu T, Zheng W, Zhu X, Evans MK, Franks PW, Gudnason V, Hayward C, Horta BL, Kelly TN, Liu Y, North KE, Pereira AC, Ridker PM, Tai ES, van Dam RM, Fox ER, Kardia SLR, Liu CT, Mook-Kanamori DO, Province MA, Redline S, van Duijn CM, Rotter JI, Kooperberg CB, Gauderman WJ, Psaty BM, Rice K, Munroe PB, Fornage M, Cupples LA, Rotimi CN, Morrison AC, Rao DC, Loos RJF | 2019-01-22 | Nature communications | |
| Longevity defined as top 10% survivors and beyond is transmitted as a quantitative genetic trait. | van den Berg N, Rodríguez-Girondo M, van Dijk IK, Mourits RJ, Mandemakers K, Janssens AAPO, Beekman M, Smith KR, Slagboom PE | 2019-01-07 | Nature communications | |
| The association between intravenous fluid resuscitation and mortality in older emergency department patients with suspected infection. | Ko SY, Esteve Cuevas LM, Willeboer M, Ansems A, Blomaard LC, Lucke JA, Mooijaart SP, de Groot B | 2019-01-05 | Emergency medicine, Fluid resuscitation, Geriatrics, Infectious diseases, Sepsis, Systolic blood pressure | International journal of emergency medicine |
| Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits. | Kraja AT, Liu C, Fetterman JL, Graff M, Have CT, Gu C, Yanek LR, Feitosa MF, Arking DE, Chasman DI, Young K, Ligthart S, Hill WD, Weiss S, Luan J, Giulianini F, Li-Gao R, Hartwig FP, Lin SJ, Wang L, Richardson TG, Yao J, Fernandez EP, Ghanbari M, Wojczynski MK, Lee WJ, Argos M, Armasu SM, Barve RA, Ryan KA, An P, Baranski TJ, Bielinski SJ, Bowden DW, Broeckel U, Christensen K, Chu AY, Corley J, Cox SR, Uitterlinden AG, Rivadeneira F, Cropp CD, Daw EW, van Heemst D, de Las Fuentes L, Gao H, Tzoulaki I, Ahluwalia TS, de Mutsert R, Emery LS, Erzurumluoglu AM, Perry JA, Fu M, Forouhi NG, Gu Z, Hai Y, Harris SE, Hemani G, Hunt SC, Irvin MR, Jonsson AE, Justice AE, Kerrison ND, Larson NB, Lin KH, Love-Gregory LD, Mathias RA, Lee JH, Nauck M, Noordam R, Ong KK, Pankow J, Patki A, Pattie A, Petersmann A, Qi Q, Ribel-Madsen R, Rohde R, Sandow K, Schnurr TM, Sofer T, Starr JM, Taylor AM, Teumer A, Timpson NJ, de Haan HG, Wang Y, Weeke PE, Williams C, Wu H, Yang W, Zeng D, Witte DR, Weir BS, Wareham NJ, Vestergaard H, Turner ST, Torp-Pedersen C, Stergiakouli E, Sheu WH, Rosendaal FR, Ikram MA, Franco OH, Ridker PM, Perls TT, Pedersen O, Nohr EA, Newman AB, Linneberg A, Langenberg C, Kilpeläinen TO, Kardia SLR, Jørgensen ME, Jørgensen T, Sørensen TIA, Homuth G, Hansen T, Goodarzi MO, Deary IJ, Christensen C, Chen YI, Chakravarti A, Brandslund I, Bonnelykke K, Taylor KD, Wilson JG, Rodriguez S, Davies G, Horta BL, Thyagarajan B, Rao DC, Grarup N, Davila-Roman VG, Hudson G, Guo X, Arnett DK, Hayward C, Vaidya D, Mook-Kanamori DO, Tiwari HK, Levy D, Loos RJF, Dehghan A, Elliott P, Malik AN, Scott RA, Becker DM, de Andrade M, Province MA, Meigs JB, Rotter JI, North KE | 2019-01-03 | BMI, HOMA-B, HOMA-IR, HbA1c, MT-nDNA candidate genes, glucose, insulin, mitochondria, mtDNA, waist-to-hip ratio | American journal of human genetics |
| Antioxidants linked with physical, cognitive and psychological frailty: Analysis of candidate biomarkers and markers derived from the MARK-AGE study. | Rietman ML, Spijkerman AMW, Wong A, van Steeg H, Bürkle A, Moreno-Villanueva M, Sindlinger T, Franceschi C, Grubeck-Loebenstein B, Bernhardt J, Slagboom PE, Toussaint O, Debacq-Chainiaux F, Sikora E, Gonos ES, Breusing N, Stuetz W, Weber D, Grune T, Basso A, Piacenza F, Malavolta M, Collino S, Jansen EHJM, Verschuren WMM, Dollé MET | 2019-01-01 | Ageing, Elastic net, Frailty, Machine learning, Multidimensional, Multivariate, Univariate | Mechanisms of ageing and development |
| Frailty Questionnaire Is Not a Strong Prognostic Factor for Functional Outcomes in Hip or Knee Arthroplasty Patients. | Meessen JMTA, Fiocco M, Leichtenberg CS, Vliet Vlieland TPM, Slagboom PE, Nelissen RGHH | 2019-01-01 | arthroplasty, frailty, osteoarthritis, rehabilitation | Geriatric orthopaedic surgery & rehabilitation |
| The ApoE ε4 Isoform: Can the Risk of Diseases be Reduced by Environmental Factors? | Bos MM, Noordam R, Blauw GJ, Slagboom PE, Rensen PCN, van Heemst D | 2019-01-01 | The journals of gerontology. Series A, Biological sciences and medical sciences | |
| A linear mixed-model approach to study multivariate gene-environment interactions. | Moore R, Casale FP, Jan Bonder M, Horta D, Franke L, Barroso I, Stegle O | 2019-01-01 | Nature genetics | |
| A genome-wide association study identifies genetic loci associated with specific lobar brain volumes. | van der Lee SJ, Knol MJ, Chauhan G, Satizabal CL, Smith AV, Hofer E, Bis JC, Hibar DP, Hilal S, van den Akker EB, Arfanakis K, Bernard M, Yanek LR, Amin N, Crivello F, Cheung JW, Harris TB, Saba Y, Lopez OL, Li S, van der Grond J, Yu L, Paus T, Roshchupkin GV, Amouyel P, Jahanshad N, Taylor KD, Yang Q, Mathias RA, Boehringer S, Mazoyer B, Rice K, Cheng CY, Maillard P, van Heemst D, Wong TY, Niessen WJ, Beiser AS, Beekman M, Zhao W, Nyquist PA, Chen C, Launer LJ, Psaty BM, Ikram MK, Vernooij MW, Schmidt H, Pausova Z, Becker DM, De Jager PL, Thompson PM, van Duijn CM, Bennett DA, Slagboom PE, Schmidt R, Longstreth WT, Ikram MA, Seshadri S, Debette S, Gudnason V, Adams HHH, DeCarli C | 2019-01-01 | Biomarkers, Genome-wide association studies, Neurology | Communications biology |
| Effectiveness of Stabilization of Preterm Infants With Intact Umbilical Cord Using a Purpose-Built Resuscitation Table-Study Protocol for a Randomized Controlled Trial. | Knol R, Brouwer E, Klumper FJCM, van den Akker T, DeKoninck P, Hutten GJ, Lopriore E, van Kaam AH, Polglase GR, Reiss IKM, Hooper SB, Te Pas AB | 2019-01-01 | newborn transition, physiological-based cord clamping, preterm infants, randomized controlled trial, resuscitation, study protocol, umbilical cord clamping | Frontiers in pediatrics |
| Measuring maternal near-miss in a middle-income country: assessing the use of WHO and sub-Saharan Africa maternal near-miss criteria in Namibia. | Heemelaar S, Kabongo L, Ithindi T, Luboya C, Munetsi F, Bauer AK, Dammann A, Drewes A, Stekelenburg J, van den Akker T, Mackenzie S | 2019-01-01 | Maternal morbidity, WHO maternal near-miss criteria, middle-income setting, morbidity registration, near-miss approach, severe maternal outcome, sub-Saharan Africa maternal near-miss criteria | Global health action |
| Spatial QRS-T Angle and Cognitive Decline in Older Subjects. | Mahinrad S, Ferguson I, Macfarlane PW, Clark EN, Stott DJ, Ford I, Mooijaart SP, Trompet S, van Heemst D, Jukema JW, Sabayan B | 2019-01-01 | Cardiac dysfunction, cognitive function, old age, spatial QRS-T angle | Journal of Alzheimer's disease : JAD |
| Vital signs and impaired cognition in older emergency department patients: The APOP study. | Lucke JA, de Gelder J, Blomaard LC, Heringhaus C, Alsma J, Klein Nagelvoort Schuit SCE, Brink A, Anten S, Blauw GJ, de Groot B, Mooijaart SP | 2019-01-01 | PloS one | |
| Repeat length variations in ATXN1 and AR modify disease expression in Alzheimer’s disease. | Gardiner SL, Harder AVE, Campman YJM, Trompet S, Gussekloo J, van Belzen MJ, Boogaard MW, Roos RAC, Jansen IE, Pijnenburg YAL, Scheltens P, van der Flier WM, Aziz NA | 2019-01-01 | Alzheimer's disease, CAG repeat polymorphisms, Huntington disease, Missing heritability, Polyglutamine diseases | Neurobiology of aging |
| Changes in patient satisfaction related to their perceived health state during implementation of improved integrated care for older persons. | Poot AJ, Wopereis DM, den Elzen WPJ, Gussekloo J, Blom JW | 2019-01-01 | PloS one | |
| Are serum autoantibodies associated with brain changes in systemic lupus erythematosus? MRI data from the Leiden NP-SLE cohort. | Magro-Checa C, Kumar S, Ramiro S, Beaart-van de Voorde LJ, Eikenboom J, Ronen I, de Bresser J, van Buchem MA, Huizinga TW, Steup-Beekman GM | 2019-01-01 | NP-SLE, Systemic lupus erythematosus, antibodies, cardiovascular risk, magnetic resonance imaging, neuropsychiatric systemic lupus erythematosus, pathogenesis | Lupus |
| The Clinical Phenotype of Vascular Cognitive Impairment in Patients with Type 2 Diabetes Mellitus. | Groeneveld ON, Moneti C, Heinen R, de Bresser J, Kuijf HJ, Exalto LG, Boomsma JMF, Kappelle LJ, Barkhof F, Prins ND, Scheltens P, van der Flier WM, Biessels GJ | 2019-01-01 | Cerebrospinal fluid, magnetic resonance imaging, prognosis, type 2 diabetes mellitus, vascular brain injury | Journal of Alzheimer's disease : JAD |
| How Do Different Forms of Vascular Brain Injury Relate to Cognition in a Memory Clinic Population: The TRACE-VCI Study. | Boomsma JMF, Exalto LG, Barkhof F, van den Berg E, de Bresser J, Heinen R, Leeuwis AE, Prins ND, Scheltens P, Weinstein HC, van der Flier WM, Biessels GJ | 2019-01-01 | Cerebral small vessel diseases, cerebrovascular disorders, cognitive disorders, neuropsychological test | Journal of Alzheimer's disease : JAD |
| Cerebral microbleeds are not associated with postoperative delirium and postoperative cognitive dysfunction in older individuals. | Lachmann G, Kant I, Lammers F, Windmann V, Spies C, Speidel S, Borchers F, Hadzidiakos D, Hendrikse J, Winterer G, de Bresser J | 2019-01-01 | PloS one | |
| Opioid Prescription Use in Nursing Home Residents with Advanced Dementia. | Griffioen C, Husebo BS, Flo E, Caljouw MAA, Achterberg WP | 2019-01-01 | Pain medicine (Malden, Mass.) | |
| Pain in patients with chronic obstructive pulmonary disease indicated for post-acute pulmonary rehabilitation. | van Dam van Isselt EF, Groenewegen-Sipkema KH, van Eijk M, Chavannes NH, Achterberg WP | 2019-01-01 | Pain, brief pain inventory, health status, symptom burden, unstable COPD | Chronic respiratory disease |
| Reliability and usability of a weighted version of the Functional Comorbidity Index. | Kabboord AD, van Eijk M, van Dingenen L, Wouters M, Koet M, van Balen R, Achterberg WP | 2019-01-01 | disease impact, function, multimorbidity, older patients, personalized medicine | Clinical interventions in aging |
| Challenging rehabilitation environment for older patients. | Tijsen LM, Derksen EW, Achterberg WP, Buijck BI | 2019-01-01 | aging, care process, geriatric rehabilitation, postacute care | Clinical interventions in aging |
| Blood Metabolomic Measures Associate With Present and Future Glycemic Control in Type 2 Diabetes. | 't Hart LM, Vogelzangs N, Mook-Kanamori DO, Brahimaj A, Nano J, van der Heijden AAWA, Willems van Dijk K, Slieker RC, Steyerberg EW, Ikram MA, Beekman M, Boomsma DI, van Duijn CM, Slagboom PE, Stehouwer CDA, Schalkwijk CG, Arts ICW, Dekker JM, Dehghan A, Muka T, van der Kallen CJH, Nijpels G, van Greevenbroek MMJ | 2018-12-01 | The Journal of clinical endocrinology and metabolism | |
| Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults. | Parmar P, Lowry E, Cugliari G, Suderman M, Wilson R, Karhunen V, Andrew T, Wiklund P, Wielscher M, Guarrera S, Teumer A, Lehne B, Milani L, de Klein N, Mishra PP, Melton PE, Mandaviya PR, Kasela S, Nano J, Zhang W, Zhang Y, Uitterlinden AG, Peters A, Schöttker B, Gieger C, Anderson D, Boomsma DI, Grabe HJ, Panico S, Veldink JH, van Meurs JBJ, van den Berg L, Beilin LJ, Franke L, Loh M, van Greevenbroek MMJ, Nauck M, Kähönen M, Hurme MA, Raitakari OT, Franco OH, Slagboom PE, van der Harst P, Kunze S, Felix SB, Zhang T, Chen W, Mori TA, Bonnefond A, Heijmans BT, Muka T, Kooner JS, Fischer K, Waldenberger M, Froguel P, Huang RC, Lehtimäki T, Rathmann W, Relton CL, Matullo G, Brenner H, Verweij N, Li S, Chambers JC, Järvelin MR, Sebert S | 2018-12-01 | EBioMedicine | |
| Facilitators for maternity waiting home utilisation at Attat Hospital: a mixed-methods study based on 45 years of experience. | Vermeiden T, Schiffer R, Langhorst J, Klappe N, Asera W, Getnet G, Stekelenburg J, van den Akker T | 2018-12-01 | Ethiopia, Ethiopie, communauté, community, community health services, foyers d'attente pour la maternité, health education, hospitals, hôpital, maternal health, maternity waiting homes, santé maternelle, services de santé communautaires, éducation à la santé | Tropical medicine & international health : TM & IH |
| Cognitive functioning and structural brain abnormalities in people with Type 2 diabetes mellitus. | Mankovsky B, Zherdova N, van den Berg E, Biessels GJ, de Bresser J | 2018-12-01 | Diabetic medicine : a journal of the British Diabetic Association | |
| Screening for malnutrition in patients admitted to the hospital with a proximal femoral fracture. | van der Sijp MPL, van Eijk M, Krijnen P, Schipper IB, Achterberg WP, Niggebrugge AHP | 2018-12-01 | ESPEN, Elderly, Hip fracture, MNA-SF, Malnourishment, Malnutrition, Older patients, Proximal femoral fracture, SNAQ, Screening | Injury |
| Quality of life and paracetamol in advanced dementia (Q-PID): protocol of a randomised double-blind placebo-controlled crossover trial. | van Dam PH, Achterberg WP, Gussekloo J, Husebo BS, Caljouw MAA | 2018-11-14 | Dementia, Nursing home, Paracetamol, QUALIDEM, Quality of life | BMC geriatrics |
| Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. | Ligthart S, Vaez A, Võsa U, Stathopoulou MG, de Vries PS, Prins BP, Van der Most PJ, Tanaka T, Naderi E, Rose LM, Wu Y, Karlsson R, Barbalic M, Lin H, Pool R, Zhu G, Macé A, Sidore C, Trompet S, Mangino M, Sabater-Lleal M, Kemp JP, Abbasi A, Kacprowski T, Verweij N, Smith AV, Huang T, Marzi C, Feitosa MF, Lohman KK, Kleber ME, Milaneschi Y, Mueller C, Huq M, Vlachopoulou E, Lyytikäinen LP, Oldmeadow C, Deelen J, Perola M, Zhao JH, Feenstra B, Amini M, Lahti J, Schraut KE, Fornage M, Suktitipat B, Chen WM, Li X, Nutile T, Malerba G, Luan J, Bak T, Schork N, Del Greco M F, Thiering E, Mahajan A, Marioni RE, Mihailov E, Eriksson J, Ozel AB, Zhang W, Nethander M, Cheng YC, Aslibekyan S, Ang W, Gandin I, Yengo L, Portas L, Kooperberg C, Hofer E, Rajan KB, Schurmann C, den Hollander W, Ahluwalia TS, Zhao J, Draisma HHM, Ford I, Timpson N, Teumer A, Huang H, Wahl S, Liu Y, Huang J, Uh HW, Geller F, Joshi PK, Yanek LR, Trabetti E, Lehne B, Vozzi D, Verbanck M, Biino G, Saba Y, Meulenbelt I, O'Connell JR, Laakso M, Giulianini F, Magnusson PKE, Ballantyne CM, Hottenga JJ, Montgomery GW, Rivadineira F, Rueedi R, Steri M, Herzig KH, Stott DJ, Menni C, Frånberg M, St Pourcain B, Felix SB, Pers TH, Bakker SJL, Kraft P, Peters A, Vaidya D, Delgado G, Smit JH, Großmann V, Sinisalo J, Seppälä I, Williams SR, Holliday EG, Moed M, Langenberg C, Räikkönen K, Ding J, Campbell H, Sale MM, Chen YI, James AL, Ruggiero D, Soranzo N, Hartman CA, Smith EN, Berenson GS, Fuchsberger C, Hernandez D, Tiesler CMT, Giedraitis V, Liewald D, Fischer K, Mellström D, Larsson A, Wang Y, Scott WR, Lorentzon M, Beilby J, Ryan KA, Pennell CE, Vuckovic D, Balkau B, Concas MP, Schmidt R, Mendes de Leon CF, Bottinger EP, Kloppenburg M, Paternoster L, Boehnke M, Musk AW, Willemsen G, Evans DM, Madden PAF, Kähönen M, Kutalik Z, Zoledziewska M, Karhunen V, Kritchevsky SB, Sattar N, Lachance G, Clarke R, Harris TB, Raitakari OT, Attia JR, van Heemst D, Kajantie E, Sorice R, Gambaro G, Scott RA, Hicks AA, Ferrucci L, Standl M, Lindgren CM, Starr JM, Karlsson M, Lind L, Li JZ, Chambers JC, Mori TA, de Geus EJCN, Heath AC, Martin NG, Auvinen J, Buckley BM, de Craen AJM, Waldenberger M, Strauch K, Meitinger T, Scott RJ, McEvoy M, Beekman M, Bombieri C, Ridker PM, Mohlke KL, Pedersen NL, Morrison AC, Boomsma DI, Whitfield JB, Strachan DP, Hofman A, Vollenweider P, Cucca F, Jarvelin MR, Jukema JW, Spector TD, Hamsten A, Zeller T, Uitterlinden AG, Nauck M, Gudnason V, Qi L, Grallert H, Borecki IB, Rotter JI, März W, Wild PS, Lokki ML, Boyle M, Salomaa V, Melbye M, Eriksson JG, Wilson JF, Penninx BWJH, Becker DM, Worrall BB, Gibson G, Krauss RM, Ciullo M, Zaza G, Wareham NJ, Oldehinkel AJ, Palmer LJ, Murray SS, Pramstaller PP, Bandinelli S, Heinrich J, Ingelsson E, Deary IJ, Mägi R, Vandenput L, van der Harst P, Desch KC, Kooner JS, Ohlsson C, Hayward C, Lehtimäki T, Shuldiner AR, Arnett DK, Beilin LJ, Robino A, Froguel P, Pirastu M, Jess T, Koenig W, Loos RJF, Evans DA, Schmidt H, Smith GD, Slagboom PE, Eiriksdottir G, Morris AP, Psaty BM, Tracy RP, Nolte IM, Boerwinkle E, Visvikis-Siest S, Reiner AP, Gross M, Bis JC, Franke L, Franco OH, Benjamin EJ, Chasman DI, Dupuis J, Snieder H, Dehghan A, Alizadeh BZ | 2018-11-01 | C-reactive protein, DEPICT, Mendelian randomization, coronary artery disease, genome-wide association study, inflammation, inflammatory disorders, schizophrenia, system biology | American journal of human genetics |
| Functional and cognitive impairment, social functioning, frailty and adverse health outcomes in older patients with esophageal cancer, a systematic review. | van Deudekom FJ, Klop HG, Hartgrink HH, Boonstra JJ, Lips IM, Slingerland M, Mooijaart SP | 2018-11-01 | Cognitive impairment, Esophageal cancer, Frailty, Functional impairment, Geriatric assessment, Older patients, Social status | Journal of geriatric oncology |
| Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation. | Teumer A, Chaker L, Groeneweg S, Li Y, Di Munno C, Barbieri C, Schultheiss UT, Traglia M, Ahluwalia TS, Akiyama M, Appel EVR, Arking DE, Arnold A, Astrup A, Beekman M, Beilby JP, Bekaert S, Boerwinkle E, Brown SJ, De Buyzere M, Campbell PJ, Ceresini G, Cerqueira C, Cucca F, Deary IJ, Deelen J, Eckardt KU, Ekici AB, Eriksson JG, Ferrrucci L, Fiers T, Fiorillo E, Ford I, Fox CS, Fuchsberger C, Galesloot TE, Gieger C, Gögele M, De Grandi A, Grarup N, Greiser KH, Haljas K, Hansen T, Harris SE, van Heemst D, den Heijer M, Hicks AA, den Hollander W, Homuth G, Hui J, Ikram MA, Ittermann T, Jensen RA, Jing J, Jukema JW, Kajantie E, Kamatani Y, Kasbohm E, Kaufman JM, Kiemeney LA, Kloppenburg M, Kronenberg F, Kubo M, Lahti J, Lapauw B, Li S, Liewald DCM, Lim EM, Linneberg A, Marina M, Mascalzoni D, Matsuda K, Medenwald D, Meisinger C, Meulenbelt I, De Meyer T, Meyer Zu Schwabedissen HE, Mikolajczyk R, Moed M, Netea-Maier RT, Nolte IM, Okada Y, Pala M, Pattaro C, Pedersen O, Petersmann A, Porcu E, Postmus I, Pramstaller PP, Psaty BM, Ramos YFM, Rawal R, Redmond P, Richards JB, Rietzschel ER, Rivadeneira F, Roef G, Rotter JI, Sala CF, Schlessinger D, Selvin E, Slagboom PE, Soranzo N, Sørensen TIA, Spector TD, Starr JM, Stott DJ, Taes Y, Taliun D, Tanaka T, Thuesen B, Tiller D, Toniolo D, Uitterlinden AG, Visser WE, Walsh JP, Wilson SG, Wolffenbuttel BHR, Yang Q, Zheng HF, Cappola A, Peeters RP, Naitza S, Völzke H, Sanna S, Köttgen A, Visser TJ, Medici M | 2018-10-26 | Nature communications | |
| The “more at home with dementia” program: a randomized controlled study protocol to determine how caregiver training affects the well-being of patients and caregivers. | Birkenhäger-Gillesse EG, Kollen BJ, Zuidema SU, Achterberg WP | 2018-10-22 | Caregiver, Dementia, Psychosocial intervention, Training | BMC geriatrics |
| Effects of the Namaste Care Family programme on quality of life of nursing home residents with advanced dementia and on family caregiving experiences: study protocol of a cluster-randomised controlled trial. | Smaling HJA, Joling KJ, van de Ven PM, Bosmans JE, Simard J, Volicer L, Achterberg WP, Francke AL, van der Steen JT | 2018-10-15 | cluster randomized control trial, dementia, family caregivers, namaste care, palliative care, quality of life | BMJ open |
| How general practitioners would deprescribe in frail oldest-old with polypharmacy – the LESS study. | Mantelli S, Jungo KT, Rozsnyai Z, Reeve E, Luymes CH, Poortvliet RKE, Chiolero A, Rodondi N, Gussekloo J, Streit S | 2018-10-12 | Complexity, Deprescribing, Frailty, Multimorbidity, Old age, Polypharmacy | BMC family practice |
| Association between fluid management and dilutional coagulopathy in severe postpartum haemorrhage: a nationwide retrospective cohort study. | Gillissen A, van den Akker T, Caram-Deelder C, Henriquez DDCA, Bloemenkamp KWM, van Roosmalen JJM, Eikenboom J, van der Bom JG | 2018-10-11 | Coagulation parameters, Dilutional coagulopathy, Fluid management, Postpartum haemorrhage | BMC pregnancy and childbirth |
| Coagulation parameters during the course of severe postpartum hemorrhage: a nationwide retrospective cohort study. | Gillissen A, van den Akker T, Caram-Deelder C, Henriquez DDCA, Bloemenkamp KWM, de Maat MPM, van Roosmalen JJM, Zwart JJ, Eikenboom J, van der Bom JG | 2018-10-09 | Blood advances | |
| Association of Thyroid Hormone Therapy With Quality of Life and Thyroid-Related Symptoms in Patients With Subclinical Hypothyroidism: A Systematic Review and Meta-analysis. | Feller M, Snel M, Moutzouri E, Bauer DC, de Montmollin M, Aujesky D, Ford I, Gussekloo J, Kearney PM, Mooijaart S, Quinn T, Stott D, Westendorp R, Rodondi N, Dekkers OM | 2018-10-02 | JAMA | |
| A characterization of postzygotic mutations identified in monozygotic twins. | Ouwens KG, Jansen R, Tolhuis B, Slagboom PE, Penninx BWJH, Boomsma DI | 2018-10-01 | genetics, mutations, next-generation sequencing, postzygotic mutations, somatic mosaicism | Human mutation |
| Habitual Sleep Measures are Associated with Overall Body Fat, and not Specifically with Visceral Fat, in Men and Women. | Dekker SA, Noordam R, Biermasz NR, de Roos A, Lamb HJ, Rosendaal FR, Rensen PCN, van Heemst D, de Mutsert R | 2018-10-01 | Obesity (Silver Spring, Md.) | |
| Maternal mortality after cesarean section in the Netherlands. | Kallianidis AF, Schutte JM, van Roosmalen J, van den Akker T | 2018-10-01 | Cesarean section, High-risk pregnancy, Maternal mortality, Obstetrics, The Netherlands | European journal of obstetrics, gynecology, and reproductive biology |
| End-of-life care in the Dutch medical curricula. | de Bruin J, Verhoef MJ, Slaets JPJ, van Bodegom D | 2018-10-01 | End-of-life care, Medical education, National blueprint | Perspectives on medical education |
| The Relation Between Thyroid Function and Anemia: A Pooled Analysis of Individual Participant Data. | Wopereis DM, Du Puy RS, van Heemst D, Walsh JP, Bremner A, Bakker SJL, Bauer DC, Cappola AR, Ceresini G, Degryse J, Dullaart RPF, Feller M, Ferrucci L, Floriani C, Franco OH, Iacoviello M, Iervasi G, Imaizumi M, Jukema JW, Khaw KT, Luben RN, Molinaro S, Nauck M, Patel KV, Peeters RP, Psaty BM, Razvi S, Schindhelm RK, van Schoor NM, Stott DJ, Vaes B, Vanderpump MPJ, Völzke H, Westendorp RGJ, Rodondi N, Cobbaert CM, Gussekloo J, den Elzen WPJ | 2018-10-01 | The Journal of clinical endocrinology and metabolism | |
| The association between brain volume, cortical brain infarcts, and physical frailty. | Kant IMJ, de Bresser J, van Montfort SJT, Aarts E, Verlaan JJ, Zacharias N, Winterer G, Spies C, Slooter AJC, Hendrikse J | 2018-10-01 | Aging, Magnetic resonance imaging, Neurodegenerative brain changes, Neurovascular brain changes, Physical frailty | Neurobiology of aging |
| Study protocol: a randomised controlled trial on the clinical effects of levothyroxine treatment for subclinical hypothyroidism in people aged 80 years and over. | Du Puy RS, Postmus I, Stott DJ, Blum MR, Poortvliet RKE, Den Elzen WPJ, Peeters RP, van Munster BC, Wolffenbuttel BHR, Westendorp RGJ, Kearney PM, Ford I, Kean S, Messow CM, Watt T, Jukema JW, Dekkers OM, Smit JWA, Rodondi N, Gussekloo J, Mooijaart SP | 2018-09-19 | 80-plus, Levothyroxine, Quality of life, Randomised controlled trial, Subclinical hypothyroidism | BMC endocrine disorders |
| An Internet-based Acceptance and Commitment Therapy intervention for older adults with anxiety complaints: study protocol for a cluster randomized controlled trial. | Witlox M, Kraaij V, Garnefski N, de Waal MWM, Smit F, Hoencamp E, Gussekloo J, Bohlmeijer ET, Spinhoven P | 2018-09-17 | Acceptance and commitment therapy, Anxiety, Anxiety complaints, Blended care, Internet, Older adults, Randomized controlled trial, Subclinical anxiety | Trials |
| Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation. | Luijk R, Wu H, Ward-Caviness CK, Hannon E, Carnero-Montoro E, Min JL, Mandaviya P, Müller-Nurasyid M, Mei H, van der Maarel SM, Relton C, Mill J, Waldenberger M, Bell JT, Jansen R, Zhernakova A, Franke L, 't Hoen PAC, Boomsma DI, van Duijn CM, van Greevenbroek MMJ, Veldink JH, Wijmenga C, van Meurs J, Daxinger L, Slagboom PE, van Zwet EW, Heijmans BT | 2018-09-14 | Nature communications | |
| Longevity Around the Turn of the 20th Century: Life-Long Sustained Survival Advantage for Parents of Today’s Nonagenarians. | Berg NVD, Rodríguez-Girondo M, de Craen AJM, Houwing-Duistermaat JJ, Beekman M, Slagboom PE | 2018-09-11 | The journals of gerontology. Series A, Biological sciences and medical sciences | |
| Implementation of a Stepwise, Multidisciplinary Intervention for Pain and Challenging Behaviour in Dementia (STA OP!): A Process Evaluation. | Pieper MJC, Achterberg WP, van der Steen JT, Francke AL | 2018-09-07 | Health Plan Implementation, behaviour, dementia, intervention, nursing homes, pain, process evaluation, program evaluation | International journal of integrated care |
| Facing up to the global challenges of ageing. | Partridge L, Deelen J, Slagboom PE | 2018-09-01 | Nature | |
| Impaired cognition is associated with adverse outcome in older patients in the Emergency Department; the Acutely Presenting Older Patients (APOP) study. | Lucke JA, de Gelder J, Heringhaus C, van der Mast RC, Fogteloo AJ, Anten S, Blauw GJ, de Groot B, Mooijaart SP | 2018-09-01 | Age and ageing | |
| Optimization of the APOP screener to predict functional decline or mortality in older emergency department patients: Cross-validation in four prospective cohorts. | de Gelder J, Lucke JA, Blomaard LC, Booijen AM, Fogteloo AJ, Anten S, Steyerberg EW, Alsma J, Klein Nagelvoort Schuit SCE, Brink A, de Groot B, Blauw GJ, Mooijaart SP | 2018-09-01 | Adverse outcomes, Emergency medical services, Older patients, Optimization, Screening | Experimental gerontology |
| Clinical aspects of thyroid function during ageing. | Chaker L, Cappola AR, Mooijaart SP, Peeters RP | 2018-09-01 | The lancet. Diabetes & endocrinology | |
| Detection and characterization of small infarcts in the caudate nucleus on 7 Tesla MRI: The SMART-MR study. | Ghaznawi R, de Bresser J, van der Graaf Y, Zwartbol MH, Witkamp TD, Geerlings MI, Hendrikse J | 2018-09-01 | 7 tesla MRI, Brain, cerebral infarcts, cerebrovascular disease, magnetic resonance imaging, small vessel disease | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism |
| Assessment Scales for Patients with Advanced Huntington’s Disease: Comparison of the UHDRS and UHDRS-FAP. | Winder JY, Achterberg WP, Marinus J, Gardiner SL, Roos RAC | 2018-09-01 | Huntington's disease, Unified Huntington's Disease Rating Scale, Unified Huntington's Disease Rating Scale‐For Advanced Patients, advanced stage, nursing home | Movement disorders clinical practice |
| DREAMeR: Drug use Reconsidered in the Elderly using goal Attainment scales during Medication Review; study protocol of a randomised controlled trial. | Verdoorn S, Kwint HF, Blom J, Gussekloo J, Bouvy ML | 2018-08-24 | Clinical medication review, Elderly, Goal attainment scaling, Pharmacists, Polypharmacy, Primary care, Randomised controlled trial | BMC geriatrics |
| Genome-wide identification of directed gene networks using large-scale population genomics data. | Luijk R, Dekkers KF, van Iterson M, Arindrarto W, Claringbould A, Hop P, Boomsma DI, van Duijn CM, van Greevenbroek MMJ, Veldink JH, Wijmenga C, Franke L, 't Hoen PAC, Jansen R, van Meurs J, Mei H, Slagboom PE, Heijmans BT, van Zwet EW | 2018-08-06 | Nature communications | |
| Facial Wrinkles in Europeans: A Genome-Wide Association Study. | Hamer MA, Pardo LM, Jacobs LC, Deelen J, Uitterlinden AG, Slagboom E, van Heemst D, Uh HW, Beekman M, Kayser M, Liu F, Gunn DA, Nijsten T | 2018-08-01 | The Journal of investigative dermatology | |
| High-sensitivity C-reactive protein, low-grade systemic inflammation and type 2 diabetes mellitus: A two-sample Mendelian randomization study. | Noordam R, Oudt CH, Bos MM, Smit RAJ, van Heemst D | 2018-08-01 | C-reactive protein, Inflammation, Mendelian randomization, Type 2 diabetes mellitus | Nutrition, metabolism, and cardiovascular diseases : NMCD |
| Birthing experience and quality of life after vacuum delivery and second-stage caesarean section: a prospective cohort study in Uganda. | Nolens B, van den Akker T, Lule J, Twinomuhangi S, van Roosmalen J, Byamugisha J | 2018-08-01 | birthing experience, caesarean section, césarienne, douleur, dyspareunia, dyspareunie, expérience de l'accouchement, extraction sous vide, pain, quality of life, qualité de vie, vacuum extraction | Tropical medicine & international health : TM & IH |
| Impact of Thyroid Hormone Therapy on Atherosclerosis in the Elderly With Subclinical Hypothyroidism: A Randomized Trial. | Blum MR, Gencer B, Adam L, Feller M, Collet TH, da Costa BR, Moutzouri E, Dopheide J, Depairon M, Sykiotis GP, Kearney P, Gussekloo J, Westendorp R, Stott DJ, Bauer DC, Rodondi N | 2018-08-01 | The Journal of clinical endocrinology and metabolism | |
| The effectiveness of functional task exercise and physical therapy as prevention of functional decline in community dwelling older people with complex health problems. | Siemonsma PC, Blom JW, Hofstetter H, van Hespen ATH, Gussekloo J, Drewes YM, van Meeteren NLU | 2018-07-17 | Exercise, Functional training, Older people | BMC geriatrics |
| Thyroid Stimulating Hormone and Bone Mineral Density: Evidence From a Two-Sample Mendelian Randomization Study and a Candidate Gene Association Study. | van Vliet NA, Noordam R, van Klinken JB, Westendorp RG, Bassett JD, Williams GR, van Heemst D | 2018-07-01 | DXA, GENERAL POPULATION STUDIES, HUMAN ASSOCIATION STUDIES, NEUROENDOCRINE | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research |
| Prospective cohort study comparing outcomes between vacuum extraction and second-stage cesarean delivery at a Ugandan tertiary referral hospital. | Nolens B, Namiiro F, Lule J, van den Akker T, van Roosmalen J, Byamugisha J | 2018-07-01 | Cesarean delivery, Instrumental delivery, Maternal morbidity, Maternal mortality, Neonatal morbidity, Perinatal mortality, Vacuum extraction, Ventouse delivery | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics |
| Lower blood pressure during antihypertensive treatment is associated with higher all-cause mortality and accelerated cognitive decline in the oldest-old. Data from the Leiden 85-plus Study. | Streit S, Poortvliet RKE, Gussekloo J | 2018-07-01 | antihypertensive treatment, cognitive function, frailty, hypertension, older people, oldest-old | Age and ageing |
| Prediction of functional decline in community-dwelling older persons in general practice: a cohort study. | van Blijswijk SCE, Blom JW, de Craen AJM, den Elzen WPJ, Gussekloo J | 2018-06-11 | Community-dwelling older person, Functional decline, General practice, Prediction, Readily available variables | BMC geriatrics |
| Change in quality of life after a multidisciplinary intervention for people with dementia: A cluster randomized controlled trial. | Klapwijk MS, Caljouw MAA, Pieper MJC, Putter H, van der Steen JT, Achterberg WP | 2018-06-11 | QUALIDEM, dementia, dementia care, long-term care, nursing home medicine, pain, quality of life | International journal of geriatric psychiatry |
| Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies. | van der Lee SJ, Teunissen CE, Pool R, Shipley MJ, Teumer A, Chouraki V, Melo van Lent D, Tynkkynen J, Fischer K, Hernesniemi J, Haller T, Singh-Manoux A, Verhoeven A, Willemsen G, de Leeuw FA, Wagner H, van Dongen J, Hertel J, Budde K, Willems van Dijk K, Weinhold L, Ikram MA, Pietzner M, Perola M, Wagner M, Friedrich N, Slagboom PE, Scheltens P, Yang Q, Gertzen RE, Egert S, Li S, Hankemeier T, van Beijsterveldt CEM, Vasan RS, Maier W, Peeters CFW, Jörgen Grabe H, Ramirez A, Seshadri S, Metspalu A, Kivimäki M, Salomaa V, Demirkan A, Boomsma DI, van der Flier WM, Amin N, van Duijn CM | 2018-06-01 | Alzheimer's disease, Cognitive function, Dementia, General cognitive ability, Lifestyle factors, Metabolites, Metabolomics, NMR | Alzheimer's & dementia : the journal of the Alzheimer's Association |
| The Leiden Family Lab study on Social Anxiety Disorder: A multiplex, multigenerational family study on neurocognitive endophenotypes. | Bas-Hoogendam JM, Harrewijn A, Tissier RLM, van der Molen MJW, van Steenbergen H, van Vliet IM, Reichart CG, Houwing-Duistermaat JJ, Slagboom PE, van der Wee NJA, Westenberg PM | 2018-06-01 | EEG, MRI, endophenotypes, family study, social anxiety disorder | International journal of methods in psychiatric research |
| Establishing a Twin Register: An Invaluable Resource for (Behavior) Genetic, Epidemiological, Biomarker, and ‘Omics’ Studies. | Odintsova VV, Willemsen G, Dolan CV, Hottenga JJ, Martin NG, Slagboom PE, Ordoñana JR, Boomsma DI | 2018-06-01 | recruitment, twin register, twin research, zygosity determination | Twin research and human genetics : the official journal of the International Society for Twin Studies |
| Regional variations in childbirth interventions in the Netherlands: a nationwide explorative study. | Seijmonsbergen-Schermers AE, Zondag DC, Nieuwenhuijze M, Van den Akker T, Verhoeven CJ, Geerts C, Schellevis F, De Jonge A | 2018-06-01 | Caesarean section, Childbirth, Induction, Interventions, Obstetric, Outcomes, Pain relief, Regional, Variations | BMC pregnancy and childbirth |
| Regression discontinuity was a valid design for dichotomous outcomes in three randomized trials. | van Leeuwen N, Lingsma HF, Mooijaart SP, Nieboer D, Trompet S, Steyerberg EW | 2018-06-01 | Causal inference, Local logistic regression, Logistic regression, Polynomials, Quasi-experimental trials, Regression discontinuity design, Restricted cubic splines, Trial design | Journal of clinical epidemiology |
| The effect of vitamin B12 and folic acid supplementation on routine haematological parameters in older people: an individual participant data meta-analysis. | Smelt AF, Gussekloo J, Bermingham LW, Allen E, Dangour AD, Eussen SJ, Favrat B, De Groot LC, Kok FJ, Kwok T, Mangoni AA, Ntaios G, Van De Rest O, Seal E, Vaucher P, Verhoef P, Stijnen T, Den Elzen WP | 2018-06-01 | European journal of clinical nutrition | |
| Perceived doctor-patient relationship and satisfaction with general practitioner care in older persons in residential homes. | de Waard CS, Poot AJ, den Elzen WPJ, Wind AW, Caljouw MAA, Gussekloo J | 2018-06-01 | Doctor-patient relationship, general practitioner, older persons, primary care, residential home, satisfaction | Scandinavian journal of primary health care |
| Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception. | Slieker RC, Relton CL, Gaunt TR, Slagboom PE, Heijmans BT | 2018-05-30 | 450 k, Ageing, DNA methylation, Tissue-specific | Epigenetics & chromatin |
| Birth preparedness and complication readiness among pregnant women admitted in a rural hospital in Rwanda. | Smeele P, Kalisa R, van Elteren M, van Roosmalen J, van den Akker T | 2018-05-30 | Birth preparedness, Complication readiness, Health promotion, High-risk pregnancy, Obstetrics, Rwanda | BMC pregnancy and childbirth |
| Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. | Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoumaki S, Giddaluru S, Gustavson DE, Hayward C, Hofer E, Ikram MA, Karlsson R, Knowles E, Lahti J, Leber M, Li S, Mather KA, Melle I, Morris D, Oldmeadow C, Palviainen T, Payton A, Pazoki R, Petrovic K, Reynolds CA, Sargurupremraj M, Scholz M, Smith JA, Smith AV, Terzikhan N, Thalamuthu A, Trompet S, van der Lee SJ, Ware EB, Windham BG, Wright MJ, Yang J, Yu J, Ames D, Amin N, Amouyel P, Andreassen OA, Armstrong NJ, Assareh AA, Attia JR, Attix D, Avramopoulos D, Bennett DA, Böhmer AC, Boyle PA, Brodaty H, Campbell H, Cannon TD, Cirulli ET, Congdon E, Conley ED, Corley J, Cox SR, Dale AM, Dehghan A, Dick D, Dickinson D, Eriksson JG, Evangelou E, Faul JD, Ford I, Freimer NA, Gao H, Giegling I, Gillespie NA, Gordon SD, Gottesman RF, Griswold ME, Gudnason V, Harris TB, Hartmann AM, Hatzimanolis A, Heiss G, Holliday EG, Joshi PK, Kähönen M, Kardia SLR, Karlsson I, Kleineidam L, Knopman DS, Kochan NA, Konte B, Kwok JB, Le Hellard S, Lee T, Lehtimäki T, Li SC, Lill CM, Liu T, Koini M, London E, Longstreth WT, Lopez OL, Loukola A, Luck T, Lundervold AJ, Lundquist A, Lyytikäinen LP, Martin NG, Montgomery GW, Murray AD, Need AC, Noordam R, Nyberg L, Ollier W, Papenberg G, Pattie A, Polasek O, Poldrack RA, Psaty BM, Reppermund S, Riedel-Heller SG, Rose RJ, Rotter JI, Roussos P, Rovio SP, Saba Y, Sabb FW, Sachdev PS, Satizabal CL, Schmid M, Scott RJ, Scult MA, Simino J, Slagboom PE, Smyrnis N, Soumaré A, Stefanis NC, Stott DJ, Straub RE, Sundet K, Taylor AM, Taylor KD, Tzoulaki I, Tzourio C, Uitterlinden A, Vitart V, Voineskos AN, Kaprio J, Wagner M, Wagner H, Weinhold L, Wen KH, Widen E, Yang Q, Zhao W, Adams HHH, Arking DE, Bilder RM, Bitsios P, Boerwinkle E, Chiba-Falek O, Corvin A, De Jager PL, Debette S, Donohoe G, Elliott P, Fitzpatrick AL, Gill M, Glahn DC, Hägg S, Hansell NK, Hariri AR, Ikram MK, Jukema JW, Vuoksimaa E, Keller MC, Kremen WS, Launer L, Lindenberger U, Palotie A, Pedersen NL, Pendleton N, Porteous DJ, Räikkönen K, Raitakari OT, Ramirez A, Reinvang I, Rudan I, Dan Rujescu, Schmidt R, Schmidt H, Schofield PW, Schofield PR, Starr JM, Steen VM, Trollor JN, Turner ST, Van Duijn CM, Villringer A, Weinberger DR, Weir DR, Wilson JF, Malhotra A, McIntosh AM, Gale CR, Seshadri S, Mosley TH, Bressler J, Lencz T, Deary IJ | 2018-05-29 | Nature communications | |
| A Role for New Brain Magnetic Resonance Imaging Modalities in Daily Clinical Practice: Protocol of the Prediction of Cognitive Recovery After Stroke (PROCRAS) Study. | Aben HP, Reijmer YD, Visser-Meily JM, Spikman JM, de Bresser J, Biessels GJ, de Kort PL | 2018-05-28 | anisotropy, brain infarction, cognitive dysfunction, diffusion magnetic resonance imaging, diffusion tensor imaging, stroke | JMIR research protocols |
| Frailty in end-stage hip or knee osteoarthritis: validation of the Groningen Frailty Indicator (GFI) questionnaire. | Meessen JMTA, Leichtenberg CS, Tilbury C, Kaptein BL, Koster LA, Slagboom PE, Verdegaal SHM, Onstenk R, van der Linden-van der Zwaag HMJ, Kaptijn H, Vehmeijer SBW, Marijnissen WC, Damen PJ, Nelissen RGHH, Vliet Vlieland TPM | 2018-05-01 | Arthroplasty, Frailty, Groningen Frailty Indicator, Osteoarthritis, Validation | Rheumatology international |
| Stress evokes stronger medial posterior cingulate deactivations during emotional distraction in slower paced aging. | Oei NYL, Jansen SW, Veer IM, Slagboom PE, van de Grond J, van Heemst D | 2018-05-01 | Aging, Cortisol, Emotional distraction, Familial longevity, HPA-axis, Medial posterior cingulate cortex, Social stress | Biological psychology |
| CETP (Cholesteryl Ester Transfer Protein) Concentration: A Genome-Wide Association Study Followed by Mendelian Randomization on Coronary Artery Disease. | Blauw LL, Li-Gao R, Noordam R, de Mutsert R, Trompet S, Berbée JFP, Wang Y, van Klinken JB, Christen T, van Heemst D, Mook-Kanamori DO, Rosendaal FR, Jukema JW, Rensen PCN, Willems van Dijk K | 2018-05-01 | cardiovascular diseases, coronary artery disease, lipids | Circulation. Genomic and precision medicine |
| Statement on Minimum Standards for the Care of Older People in Emergency Departments by the Geriatric Emergency Medicine Special Interest Group of the International Federation for Emergency Medicine. | Ellis B, Carpenter CR, Lowthian JA, Mooijaart SP, Nickel CH, Melady D | 2018-05-01 | geriatric emergency medicine, international, older people, standards | CJEM |
| The Six-Item Cognitive Impairment Test Is Associated with Adverse Outcomes in Acutely Hospitalized Older Patients: A Prospective Cohort Study. | Lucke JA, van der Mast RC, de Gelder J, Heim N, de Groot B, Mooijaart SP, Blauw GJ | 2018-05-01 | Acute care, Cognitive impairment, Functional impairment, Geriatrics, Hospital admission, Hospital length of stay, Mortality, Older patients, Six-Item Cognitive Impairment Test | Dementia and geriatric cognitive disorders extra |
| Association of diastolic blood pressure with cardiovascular events in older people varies upon cardiovascular history. | Wijsman LW, Muller M, de Craen AJM, Jukema JW, Westendorp RGJ, Mooijaart SP | 2018-04-01 | Journal of hypertension | |
| Nuclear magnetic resonance-based metabolomics identifies phenylalanine as a novel predictor of incident heart failure hospitalisation: results from PROSPER and FINRISK 1997. | Delles C, Rankin NJ, Boachie C, McConnachie A, Ford I, Kangas A, Soininen P, Trompet S, Mooijaart SP, Jukema JW, Zannad F, Ala-Korpela M, Salomaa V, Havulinna AS, Welsh P, Würtz P, Sattar N | 2018-04-01 | Advanced lipoprotein profiling, FINRISK, Heart failure, Metabolomics, PROSPER, Phenylalanine | European journal of heart failure |
| Predictors and Outcomes of Revisits in Older Adults Discharged from the Emergency Department. | de Gelder J, Lucke JA, de Groot B, Fogteloo AJ, Anten S, Heringhaus C, Dekkers OM, Blauw GJ, Mooijaart SP | 2018-04-01 | Emergency Department, adverse outcomes, emergency medical services, older patients, revisits | Journal of the American Geriatrics Society |
| Drug-related problems identified during medication review before and after the introduction of a clinical decision support system. | Verdoorn S, Kwint HF, Hoogland P, Gussekloo J, Bouvy ML | 2018-04-01 | computerised decision support, elderly, medication, pharmacist consultation, pharmacy practice | Journal of clinical pharmacy and therapeutics |
| Unravelling complex primary-care programs to maintain independent living in older people: a systematic overview. | Smit LC, Schuurmans MJ, Blom JW, Fabbricotti IN, Jansen APD, Kempen GIJM, Koopmans R, Looman WM, Melis RJF, Metzelthin SF, Moll van Charante EP, Muntinga ME, Ruikes FGH, Spoorenberg SLW, Suijker JJ, Wynia K, Gussekloo J, De Wit NJ, Bleijenberg N | 2018-04-01 | Complex interventions, Development, Evaluation, Improvement, Primary-care programs, Systematic overview | Journal of clinical epidemiology |
| BeCaf study: caffeine and behaviour in nursing homes, a study protocol and EBM training program. | Kromhout MA, van Eijk M, Pieper MJC, Chel VGM, Achterberg WP, Numans ME | 2018-04-01 | The Netherlands journal of medicine | |
| A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening. | van den Berg R, Kooijman S, Noordam R, Ramkisoensing A, Abreu-Vieira G, Tambyrajah LL, Dijk W, Ruppert P, Mol IM, Kramar B, Caputo R, Puig LS, de Ruiter EM, Kroon J, Hoekstra M, van der Sluis RJ, Meijer OC, Willems van Dijk K, van Kerkhof LWM, Christodoulides C, Karpe F, Gerhart-Hines Z, Kersten S, Meijer JH, Coomans CP, van Heemst D, Biermasz NR, Rensen PCN | 2018-03-27 | APOE(∗)3-Leiden.CETP mice, angiopoietin-like 4, brown adipose tissue, circadian rhythm, diurnal rhythm, fatty acids, lipoprotein lipase, postprandial lipid response, triglycerides | Cell reports |
| Prevalence of potentially inappropriate prescribing in a subpopulation of older European clinical trial participants: a cross-sectional study. | O Riordan D, Aubert CE, Walsh KA, Van Dorland A, Rodondi N, Du Puy RS, Poortvliet RKE, Gussekloo J, Sinnott C, Byrne S, Galvin R, Jukema JW, Mooijaart SP, Baumgartner C, McCarthy V, Walsh EK, Collet TH, Dekkers OM, Blum MR, Kearney PM | 2018-03-22 | primary care | BMJ open |
| Visit-to-visit lipid variability: Clinical significance, effects of lipid-lowering treatment, and (pharmaco) genetics. | Smit RAJ, Jukema JW, Postmus I, Ford I, Slagboom PE, Heijmans BT, Le Cessie S, Trompet S | 2018-03-01 | GWAS, Lipoprotein, Pharmacogenetics, Risk factor, Vascular disease, Visit-to-visit variability | Journal of clinical lipidology |
| IgG glycosylation and DNA methylation are interconnected with smoking. | Wahl A, Kasela S, Carnero-Montoro E, van Iterson M, Štambuk J, Sharma S, van den Akker E, Klaric L, Benedetti E, Razdorov G, Trbojević-Akmačić I, Vučković F, Ugrina I, Beekman M, Deelen J, van Heemst D, Heijmans BT, B I O S Consortium, Wuhrer M, Plomp R, Keser T, Šimurina M, Pavić T, Gudelj I, Krištić J, Grallert H, Kunze S, Peters A, Bell JT, Spector TD, Milani L, Slagboom PE, Lauc G, Gieger C | 2018-03-01 | DNA methylation, EWAS, IgG glycosylation, Mediation, Smoking | Biochimica et biophysica acta. General subjects |
| Vitality club: a proof-of-principle of peer coaching for daily physical activity by older adults. | van de Vijver PL, Wielens H, Slaets JPJ, van Bodegom D | 2018-03-01 | Translational behavioral medicine | |
| Burden of cardiovascular disease across 29 countries and GPs’ decision to treat hypertension in oldest-old. | Streit S, Gussekloo J, Burman RA, Collins C, Kitanovska BG, Gintere S, Gómez Bravo R, Hoffmann K, Iftode C, Johansen KL, Kerse N, Koskela TH, Peštić SK, Kurpas D, Mallen CD, Maisonneuve H, Merlo C, Mueller Y, Muth C, Ornelas RH, Šter MP, Petrazzuoli F, Rosemann T, Sattler M, Švadlenková Z, Tatsioni A, Thulesius H, Tkachenko V, Torzsa P, Tsopra R, Tuz C, Verschoor M, Viegas RPA, Vinker S, de Waal MWM, Zeller A, Rodondi N, Poortvliet RKE | 2018-03-01 | Oldest-old, cardiovascular disease burden, clinical decision-making, hypertension, life expectancy | Scandinavian journal of primary health care |
| Long-term restrictions in participation in stroke survivors under and over 70 years of age. | de Graaf JA, van Mierlo ML, Post MWM, Achterberg WP, Kappelle LJ, Visser-Meily JMA | 2018-03-01 | CVA, USER-P, elderly, emotional functioning, predictors, restore4stroke | Disability and rehabilitation |
| Effects on pain of a stepwise multidisciplinary intervention (STA OP!) that targets pain and behavior in advanced dementia: A cluster randomized controlled trial. | Pieper MJC, van der Steen JT, Francke AL, Scherder EJA, Twisk JWR, Achterberg WP | 2018-03-01 | Pain, dementia, nursing homes, pain management, randomized controlled trial | Palliative medicine |
| Effects of two feedback interventions on end-of-life outcomes in nursing home residents with dementia: A cluster-randomized controlled three-armed trial. | Boogaard JA, de Vet HCW, van Soest-Poortvliet MC, Anema JR, Achterberg WP, van der Steen JT | 2018-03-01 | Palliative care, dementia, nursing homes, quality improvement, quality of health care | Palliative medicine |
| Effects of Psychosocial Interventions for Behavioral and Psychological Symptoms in Dementia on the Prescription of Psychotropic Drugs: A Systematic Review and Meta-Analyses. | Birkenhäger-Gillesse EG, Kollen BJ, Achterberg WP, Boersma F, Jongman L, Zuidema SU | 2018-03-01 | Nursing homes, antipsychotics, dementia, psychosocial intervention, psychotropic drugs, systematic review | Journal of the American Medical Directors Association |
| Do senescence markers correlate in vitro and in situ within individual human donors? | Waaijer MEC, Gunn DA, van Heemst D, Slagboom PE, Sedivy JM, Dirks RW, Tanke HJ, Westendorp RGJ, Maier AB | 2018-02-28 | cellular senescence, correlation, in situ, in vitro, markers | Aging |
| Laparotomy in women with severe acute maternal morbidity: secondary analysis of a nationwide cohort study. | Witteveen T, Kallianidis A, Zwart JJ, Bloemenkamp KW, van Roosmalen J, van den Akker T | 2018-02-27 | Cesarean section, Childbirth, Cohort studies, High-risk pregnancy, Laparotomy, Maternal mortality, Obstetric surgical procedures, Obstetrics, Severe acute maternal morbidity | BMC pregnancy and childbirth |
| Interrelationship of the rs7903146 TCF7L2 gene variant with measures of glucose metabolism and adiposity: The NEO study. | Noordam R, Zwetsloot CPA, de Mutsert R, Mook-Kanamori DO, Lamb HJ, de Roos A, de Koning EJP, Rosendaal FR, Willems van Dijk K, van Heemst D | 2018-02-01 | Adiposity, Diabetes, Glucose, Insulin, TCF7L2 | Nutrition, metabolism, and cardiovascular diseases : NMCD |
| Association of complement receptor 1 gene polymorphisms with cognitive function. | Zijlstra LE, Jukema JW, Mooijaart SP, de Vries MA, Stott DJ, Castro Cabezas M, Trompet S | 2018-02-01 | Alzheimer’s disease, chromosome 1, cognitive function, complement receptor 1, older patients | Physiological genomics |
| White matter hyperintensity shape and location feature analysis on brain MRI; proof of principle study in patients with diabetes. | de Bresser J, Kuijf HJ, Zaanen K, Viergever MA, Hendrikse J, Biessels GJ | 2018-01-30 | Scientific reports | |
| A SNP panel for identification of DNA and RNA specimens. | Yousefi S, Abbassi-Daloii T, Kraaijenbrink T, Vermaat M, Mei H, van 't Hof P, van Iterson M, Zhernakova DV, Claringbould A, Franke L, 't Hart LM, Slieker RC, van der Heijden A, de Knijff P, 't Hoen PAC | 2018-01-25 | Biobanking, Forensics, Genetic variation, Mix up samples, Sample tracking | BMC genomics |
| Medical and moral considerations regarding complex medical decisions in older patients with multimorbidity: a compact deliberation framework. | Janssens JFAM, de Kort SJ, Achterberg WP, Kurrle S, Kerse N, Cameron ID, Touwen DP | 2018-01-25 | Elderly, Intercurrent disease, Medical decision, Multimorbidity, Shared decision making | BMC geriatrics |
| Factors associated with intended use of a maternity waiting home in Southern Ethiopia: a community-based cross-sectional study. | Vermeiden T, Braat F, Medhin G, Gaym A, van den Akker T, Stekelenburg J | 2018-01-19 | Ethiopia, Health-seeking behaviour, Maternal health, Maternal mortality, Maternity waiting homes, Obstetrics | BMC pregnancy and childbirth |
| Variations in childbirth interventions in high-income countries: protocol for a multinational cross-sectional study. | Seijmonsbergen-Schermers A, van den Akker T, Beeckman K, Bogaerts A, Barros M, Janssen P, Binfa L, Rydahl E, Frith L, Gross MM, Hálfdánsdóttir B, Daly D, Calleja-Agius J, Gillen P, Vika Nilsen AB, Declercq E, de Jonge A | 2018-01-10 | caesarean section, childbirth interventions, episiotomy, instrumental delivery, international variations, maternal and perinatal outcmes | BMJ open |
| Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group. | Floyd JS, Sitlani CM, Avery CL, Noordam R, Li X, Smith AV, Gogarten SM, Li J, Broer L, Evans DS, Trompet S, Brody JA, Stewart JD, Eicher JD, Seyerle AA, Roach J, Lange LA, Lin HJ, Kors JA, Harris TB, Li-Gao R, Sattar N, Cummings SR, Wiggins KL, Napier MD, Stürmer T, Bis JC, Kerr KF, Uitterlinden AG, Taylor KD, Stott DJ, de Mutsert R, Launer LJ, Busch EL, Méndez-Giráldez R, Sotoodehnia N, Soliman EZ, Li Y, Duan Q, Rosendaal FR, Slagboom PE, Wilhelmsen KC, Reiner AP, Chen YD, Heckbert SR, Kaplan RC, Rice KM, Jukema JW, Johnson AD, Liu Y, Mook-Kanamori DO, Gudnason V, Wilson JG, Rotter JI, Laurie CC, Psaty BM, Whitsel EA, Cupples LA, Stricker BH | 2018-01-01 | The pharmacogenomics journal | |
| DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood. | Tobi EW, Slieker RC, Luijk R, Dekkers KF, Stein AD, Xu KM, Slagboom PE, van Zwet EW, Lumey LH, Heijmans BT | 2018-01-01 | Science advances | |
| Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study. | Molnos S, Wahl S, Haid M, Eekhoff EMW, Pool R, Floegel A, Deelen J, Much D, Prehn C, Breier M, Draisma HH, van Leeuwen N, Simonis-Bik AMC, Jonsson A, Willemsen G, Bernigau W, Wang-Sattler R, Suhre K, Peters A, Thorand B, Herder C, Rathmann W, Roden M, Gieger C, Kramer MHH, van Heemst D, Pedersen HK, Gudmundsdottir V, Schulze MB, Pischon T, de Geus EJC, Boeing H, Boomsma DI, Ziegler AG, Slagboom PE, Hummel S, Beekman M, Grallert H, Brunak S, McCarthy MI, Gupta R, Pearson ER, Adamski J, 't Hart LM | 2018-01-01 | Epidemiology, Insulin secretion, Metabolomics, Prediction of diabetes, Type 2 diabetes | Diabetologia |
| Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns. | Wahl A, van den Akker E, Klaric L, Štambuk J, Benedetti E, Plomp R, Razdorov G, Trbojević-Akmačić I, Deelen J, van Heemst D, Slagboom PE, Vučković F, Grallert H, Krumsiek J, Strauch K, Peters A, Meitinger T, Hayward C, Wuhrer M, Beekman M, Lauc G, Gieger C | 2018-01-01 | LC–ESI-MS, RUNX3, genome-wide association study, glycosylation, immunoglobulin G | Frontiers in immunology |
| Natriuretic Peptides in Post-mortem Brain Tissue and Cerebrospinal Fluid of Non-demented Humans and Alzheimer’s Disease Patients. | Mahinrad S, Bulk M, van der Velpen I, Mahfouz A, van Roon-Mom W, Fedarko N, Yasar S, Sabayan B, van Heemst D, van der Weerd L | 2018-01-01 | Alzheimer disease, brain, cerebrospinal fluid, gene expression, humans, natriuretic peptides | Frontiers in neuroscience |
| DNA methylation signatures of educational attainment. | van Dongen J, Bonder MJ, Dekkers KF, Nivard MG, van Iterson M, Willemsen G, Beekman M, van der Spek A, van Meurs JBJ, Franke L, Heijmans BT, van Duijn CM, Slagboom PE, Boomsma DI | 2018-01-01 | NPJ science of learning | |
| Comparison of pregnancy outcomes between maternity waiting home users and non-users at hospitals with and without a maternity waiting home: retrospective cohort study. | Braat F, Vermeiden T, Getnet G, Schiffer R, van den Akker T, Stekelenburg J | 2018-01-01 | International health | |
| Facilitators and barriers to birth preparedness and complication readiness in rural Rwanda among community health workers and community members: a qualitative study. | Kalisa R, Smeele P, van Elteren M, van den Akker T, van Roosmalen J | 2018-01-01 | Perceptions, Pregnancy, facility delivery, birth preparedness, Respectful maternity care | Maternal health, neonatology and perinatology |
| Severe maternal outcomes in eastern Ethiopia: Application of the adapted maternal near miss tool. | Tura AK, Zwart J, van Roosmalen J, Stekelenburg J, van den Akker T, Scherjon S | 2018-01-01 | PloS one | |
| Early prediction of hospital admission for emergency department patients: a comparison between patients younger or older than 70 years. | Lucke JA, de Gelder J, Clarijs F, Heringhaus C, de Craen AJM, Fogteloo AJ, Blauw GJ, Groot B, Mooijaart SP | 2018-01-01 | aged, emergency department, epidemiology., geriatrics, hospitalizations, research | Emergency medicine journal : EMJ |
| High Adiposity Is Associated With Higher Nocturnal and Diurnal Glycaemia, but Not With Glycemic Variability in Older Individuals Without Diabetes. | Noordam R, Huurman NC, Wijsman CA, Akintola AA, Jansen SWM, Stassen S, Beekman M, van de Rest O, Slagboom PE, Mooijaart SP, van Heemst D | 2018-01-01 | adiposity, body composition, continuous glucose monitoring, glycemia, glycemic variability | Frontiers in endocrinology |
| Association between subclinical thyroid dysfunction and change in bone mineral density in prospective cohorts. | Segna D, Bauer DC, Feller M, Schneider C, Fink HA, Aubert CE, Collet TH, da Costa BR, Fischer K, Peeters RP, Cappola AR, Blum MR, van Dorland HA, Robbins J, Naylor K, Eastell R, Uitterlinden AG, Rivadeneira Ramirez F, Gogakos A, Gussekloo J, Williams GR, Schwartz A, Cauley JA, Aujesky DA, Bischoff-Ferrari HA, Rodondi N | 2018-01-01 | bone density, bone loss, hyperthyroidism, hypothyroidism, prospective studies, thyroid disease | Journal of internal medicine |
| Wishes and needs of community-dwelling older persons concerning general practice: A qualitative study. | van Blijswijk SCE, de Waard CS, van Peet PG, Keizer D, von Faber M, de Waal MWM, den Elzen WPJ, Gussekloo J, Blom JW | 2018-01-01 | PloS one | |
| Evaluation of a deep learning approach for the segmentation of brain tissues and white matter hyperintensities of presumed vascular origin in MRI. | Moeskops P, de Bresser J, Kuijf HJ, Mendrik AM, Biessels GJ, Pluim JPW, Išgum I | 2018-01-01 | Brain MRI, Brain atrophy, Convolutional neural networks, Deep learning, Motion artefacts, Segmentation, White matter hyperintensities | NeuroImage. Clinical |
| Fast CSF MRI for brain segmentation; Cross-validation by comparison with 3D T1-based brain segmentation methods. | van der Kleij LA, de Bresser J, Hendrikse J, Siero JCW, Petersen ET, De Vis JB | 2018-01-01 | PloS one | |
| The cumulative effect of small vessel disease lesions is reflected in structural brain networks of memory clinic patients. | Heinen R, Vlegels N, de Bresser J, Leemans A, Biessels GJ, Reijmer YD | 2018-01-01 | Cerebral small vessel disease, Cognition, Diffusion-weighted imaging, Magnetic resonance imaging, Vascular cognitive impairment | NeuroImage. Clinical |
| Parietal Involvement in Constructional Apraxia as Measured Using the Pentagon Copying Task. | Van der Stigchel S, de Bresser J, Heinen R, Koek HL, Reijmer YD, Biessels GJ, van den Berg E | 2018-01-01 | Constructional apraxia, Neurodegenerative disease, Visual attention | Dementia and geriatric cognitive disorders |
| Pain Assessment in Impaired Cognition (PAIC): content validity of the Dutch version of a new and universal tool to measure pain in dementia. | van Dalen-Kok AH, Achterberg WP, Rijkmans WE, Tukker-van Vuuren SA, Delwel S, de Vet HC, Lobbezoo F, de Waal MW | 2018-01-01 | content validity, dementia, education, nursing home, observational pain measurement tool, pain | Clinical interventions in aging |
| [Death after a fall in patients with advanced dementia: cause of death natural or unnatural?]. | van Dingenen ECM, van Eijk M, Chel VGM, Engberts DP, Achterberg WP | 2018-01-01 | Nederlands tijdschrift voor geneeskunde | |
| Comorbidity and intercurrent diseases in geriatric stroke rehabilitation: a multicentre observational study in skilled nursing facilities. | Kabboord AD, Van Eijk M, Buijck BI, Koopmans RTCM, van Balen R, Achterberg WP | 2018-01-01 | Comorbidity, Functional impairments, Geriatric rehabilitation, Intercurrent diseases, Stroke | European geriatric medicine |
| Marriage as Protector for Nursing Home Admission in Huntington’s Disease. | Winder JY, Achterberg WP, Roos RAC | 2018-01-01 | Huntington’s disease, advanced stage, functional assessment, marriage, nursing home admission | Journal of Huntington's disease |
| Geriatric rehabilitation in older patients with cardiovascular disease: a feasibility study. | van Dam van Isselt EF, van Wijngaarden J, Lok DJA, Achterberg WP | 2018-01-01 | Cardiac surgery, Cardiovascular disease, Feasibility, Geriatric rehabilitation, Heart failure | European geriatric medicine |
| Adaptation of the WHO maternal near miss tool for use in sub-Saharan Africa: an International Delphi study. | Tura AK, Stekelenburg J, Scherjon SA, Zwart J, van den Akker T, van Roosmalen J, Gordijn SJ | 2017-12-29 | Delphi, Global health, Maternal near miss, Severe maternal morbidity, Sub–Saharan Africa | BMC pregnancy and childbirth |
| DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation. | Richard MA, Huan T, Ligthart S, Gondalia R, Jhun MA, Brody JA, Irvin MR, Marioni R, Shen J, Tsai PC, Montasser ME, Jia Y, Syme C, Salfati EL, Boerwinkle E, Guan W, Mosley TH, Bressler J, Morrison AC, Liu C, Mendelson MM, Uitterlinden AG, van Meurs JB, Franco OH, Zhang G, Li Y, Stewart JD, Bis JC, Psaty BM, Chen YI, Kardia SLR, Zhao W, Turner ST, Absher D, Aslibekyan S, Starr JM, McRae AF, Hou L, Just AC, Schwartz JD, Vokonas PS, Menni C, Spector TD, Shuldiner A, Damcott CM, Rotter JI, Palmas W, Liu Y, Paus T, Horvath S, O'Connell JR, Guo X, Pausova Z, Assimes TL, Sotoodehnia N, Smith JA, Arnett DK, Deary IJ, Baccarelli AA, Bell JT, Whitsel E, Dehghan A, Levy D, Fornage M | 2017-12-07 | DNA methylation, Mendelian randomization, blood pressure, epigenome-wide association study, gene expression, sequence variation | American journal of human genetics |
| Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand. | den Hollander W, Boer CG, Hart DJ, Yau MS, Ramos YFM, Metrustry S, Broer L, Deelen J, Cupples LA, Rivadeneira F, Kloppenburg M, Peters M, Spector TD, Hofman A, Slagboom PE, Nelissen RGHH, Uitterlinden AG, Felson DT, Valdes AM, Meulenbelt I, van Meurs JJB | 2017-12-01 | Matrix-Gla protein, functional study, genetics, genome-wide association study, hand osteoarthritis | Annals of the rheumatic diseases |
| Maternal mortality: direct or indirect has become irrelevant. | van den Akker T, Nair M, Goedhart M, Schutte J, Schaap T, Knight M | 2017-12-01 | The Lancet. Global health | |
| Thyroid Function Within the Normal Range, Subclinical Hypothyroidism, and the Risk of Atrial Fibrillation. | Baumgartner C, da Costa BR, Collet TH, Feller M, Floriani C, Bauer DC, Cappola AR, Heckbert SR, Ceresini G, Gussekloo J, den Elzen WPJ, Peeters RP, Luben R, Völzke H, Dörr M, Walsh JP, Bremner A, Iacoviello M, Macfarlane P, Heeringa J, Stott DJ, Westendorp RGJ, Khaw KT, Magnani JW, Aujesky D, Rodondi N | 2017-11-28 | atrial fibrillation, hypothyroidism, thyrotropin, thyroxine | Circulation |
| Emergency obstetric care provision in Southern Ethiopia: a facility-based survey. | Windsma M, Vermeiden T, Braat F, Tsegaye AM, Gaym A, van den Akker T, Stekelenburg J | 2017-11-08 | emergency obstetric and neonatal care, health care facilities, manpower and services, maternal health services, maternal mortality, quality of Health care | BMJ open |
| Homocysteine levels associate with subtle changes in leukocyte DNA methylation: an epigenome-wide analysis. | Mandaviya PR, Aïssi D, Dekkers KF, Joehanes R, Kasela S, Truong V, Stolk L, Heemst DV, Ikram MA, Lindemans J, Slagboom PE, Trégouët DA, Uitterlinden AG, Wei C, Wells P, Gagnon F, van Greevenbroek MM, Heijmans BT, Milani L, Morange PE, van Meurs JB, Heil SG | 2017-11-01 | 450 k array, DMP, DMR, DNA methylation, association, epigenome-wide analysis, homocysteine, meta-analysis | Epigenomics |
| No Causal Association between 25-Hydroxyvitamin D and Features of Skin Aging: Evidence from a Bidirectional Mendelian Randomization Study. | Noordam R, Hamer MA, Pardo LM, van der Nat T, Kiefte-de Jong JC, Kayser M, Slagboom PE, Uitterlinden A, Zillikens MC, Beekman M, Nijsten T, van Heemst D, Gunn DA | 2017-11-01 | The Journal of investigative dermatology | |
| The Cognitive decline in Older Patients with End stage renal disease (COPE) study – rationale and design. | Berkhout-Byrne N, Kallenberg MH, Gaasbeek A, Rabelink TJ, Hammer S, van Buchem MA, van Osch MJ, Kroft LJM, Boom H, Mooijaart SP, van Buren M | 2017-11-01 | Cognition, ESRD, dialysis, small vessel disease | Current medical research and opinion |
| Optimising the ISAR-HP to screen efficiently for functional decline in older patients. | de Gelder J, Haenen E, Lucke JA, Klop HG, Blomaard LC, Smit RAJ, Mesri K, de Groot B, Fogteloo AJ, Anten S, Blauw GJ, Mooijaart SP | 2017-11-01 | The Netherlands journal of medicine | |
| Thyroid status and mortality in nonagenarians from long-lived families and the general population. | van Vliet NA, van der Spoel E, Beekman M, Slagboom PE, Blauw GJ, Gussekloo J, Westendorp RGJ, van Heemst D | 2017-10-25 | familial, longevity, mortality, nonagenarians, thyroid | Aging |
| Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. | Joshi PK, Pirastu N, Kentistou KA, Fischer K, Hofer E, Schraut KE, Clark DW, Nutile T, Barnes CLK, Timmers PRHJ, Shen X, Gandin I, McDaid AF, Hansen TF, Gordon SD, Giulianini F, Boutin TS, Abdellaoui A, Zhao W, Medina-Gomez C, Bartz TM, Trompet S, Lange LA, Raffield L, van der Spek A, Galesloot TE, Proitsi P, Yanek LR, Bielak LF, Payton A, Murgia F, Concas MP, Biino G, Tajuddin SM, Seppälä I, Amin N, Boerwinkle E, Børglum AD, Campbell A, Demerath EW, Demuth I, Faul JD, Ford I, Gialluisi A, Gögele M, Graff M, Hingorani A, Hottenga JJ, Hougaard DM, Hurme MA, Ikram MA, Jylhä M, Kuh D, Ligthart L, Lill CM, Lindenberger U, Lumley T, Mägi R, Marques-Vidal P, Medland SE, Milani L, Nagy R, Ollier WER, Peyser PA, Pramstaller PP, Ridker PM, Rivadeneira F, Ruggiero D, Saba Y, Schmidt R, Schmidt H, Slagboom PE, Smith BH, Smith JA, Sotoodehnia N, Steinhagen-Thiessen E, van Rooij FJA, Verbeek AL, Vermeulen SH, Vollenweider P, Wang Y, Werge T, Whitfield JB, Zonderman AB, Lehtimäki T, Evans MK, Pirastu M, Fuchsberger C, Bertram L, Pendleton N, Kardia SLR, Ciullo M, Becker DM, Wong A, Psaty BM, van Duijn CM, Wilson JG, Jukema JW, Kiemeney L, Uitterlinden AG, Franceschini N, North KE, Weir DR, Metspalu A, Boomsma DI, Hayward C, Chasman D, Martin NG, Sattar N, Campbell H, Esko T, Kutalik Z, Wilson JF | 2017-10-13 | Nature communications | |
| Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism. | van Vliet NA, Noordam R, van Heemst D | 2017-10-05 | The New England journal of medicine | |
| Lessons from Mendelian randomization studies on liver biomarkers: response to Abbasi. | Noordam R, Smit RAJ, Postmus I, Trompet S, van Heemst D | 2017-10-01 | International journal of epidemiology | |
| Genetic variation in the obesity gene FTO is not associated with decreased fat oxidation: the NEO study. | Blauw LL, Noordam R, Trompet S, Berbée JFP, Rosendaal FR, van Heemst D, van Dijk KW, Mook-Kanamori DO, de Mutsert R, Rensen PCN | 2017-10-01 | International journal of obesity (2005) | |
| Impact of age, sex and body mass index on cortisol secretion in 143 healthy adults. | Roelfsema F, van Heemst D, Iranmanesh A, Takahashi P, Yang R, Veldhuis JD | 2017-10-01 | approximate entropy, circadian rhythms, cortisol, deconvolution, human | Endocrine connections |
| MRI Markers of Neurodegenerative and Neurovascular Changes in Relation to Postoperative Delirium and Postoperative Cognitive Decline. | Kant IMJ, de Bresser J, van Montfort SJT, Slooter AJC, Hendrikse J | 2017-10-01 | Postoperative delirium, magnetic resonance imaging, neurodegenerative brain changes, neurovascular brain changes, postoperative cognitive decline | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry |
| Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health. | Plomp R, Ruhaak LR, Uh HW, Reiding KR, Selman M, Houwing-Duistermaat JJ, Slagboom PE, Beekman M, Wuhrer M | 2017-09-26 | Scientific reports | |
| The most commonly used disease severity scores are inappropriate for risk stratification of older emergency department sepsis patients: an observational multi-centre study. | de Groot B, Stolwijk F, Warmerdam M, Lucke JA, Singh GK, Abbas M, Mooijaart SP, Ansems A, Esteve Cuevas L, Rijpsma D | 2017-09-11 | Disease severity scores, Emergency medical services, Infectious diseases, Mortality, Older patients, Risk stratification, Sepsis, qSOFA | Scandinavian journal of trauma, resuscitation and emergency medicine |
| Classification of maternal deaths: where does the chain of events start? | van den Akker T, Bloemenkamp KWM, van Roosmalen J, Knight M | 2017-09-02 | Lancet (London, England) | |
| Activation-Induced Autophagy Is Preserved in CD4+ T-Cells in Familial Longevity. | Raz Y, Guerrero-Ros I, Maier A, Slagboom PE, Atzmon G, Barzilai N, Macian F | 2017-09-01 | CD4+ T-cell, Centenarians, Immunosenescence, Macroautophagy, Proteostasis | The journals of gerontology. Series A, Biological sciences and medical sciences |
| Historical demography and longevity genetics: Back to the future. | van den Berg N, Beekman M, Smith KR, Janssens A, Slagboom PE | 2017-09-01 | Demography, Genetics, Historical data, Inheritance, Longevity, Review | Ageing research reviews |
| Small nucleoli are a cellular hallmark of longevity. | Tiku V, Jain C, Raz Y, Nakamura S, Heestand B, Liu W, Späth M, Suchiman HED, Müller RU, Slagboom PE, Partridge L, Antebi A | 2017-08-30 | Nature communications | |
| Maternal and perinatal outcome after previous caesarean section in rural Rwanda. | Kalisa R, Rulisa S, van Roosmalen J, van den Akker T | 2017-08-25 | Elective repeat caesarean delivery, Maternal morbidity, Sub-Saharan Africa, Trial of labor, Vaginal birth after caesarean section | BMC pregnancy and childbirth |
| Systemic Age-Associated DNA Hypermethylation of ELOVL2 Gene: In Vivo and In Vitro Evidences of a Cell Replication Process. | Bacalini MG, Deelen J, Pirazzini C, De Cecco M, Giuliani C, Lanzarini C, Ravaioli F, Marasco E, van Heemst D, Suchiman HED, Slieker R, Giampieri E, Recchioni R, Marcheselli F, Salvioli S, Vitale G, Olivieri F, Spijkerman AMW, Dollé MET, Sedivy JM, Castellani G, Franceschi C, Slagboom PE, Garagnani P | 2017-08-01 | Biomarker, Epigenetics, FHL2, Methylation | The journals of gerontology. Series A, Biological sciences and medical sciences |
| High-Sensitivity Cardiac Troponin Concentration and Risk of First-Ever Cardiovascular Outcomes in 154,052 Participants. | Willeit P, Welsh P, Evans JDW, Tschiderer L, Boachie C, Jukema JW, Ford I, Trompet S, Stott DJ, Kearney PM, Mooijaart SP, Kiechl S, Di Angelantonio E, Sattar N | 2017-08-01 | biomarker, cardiovascular disease, coronary heart disease, primary prevention, stroke, systematic review | Journal of the American College of Cardiology |
| Thyroid Function Tests in the Reference Range and Fracture: Individual Participant Analysis of Prospective Cohorts. | Aubert CE, Floriani C, Bauer DC, da Costa BR, Segna D, Blum MR, Collet TH, Fink HA, Cappola AR, Syrogiannouli L, Peeters RP, Åsvold BO, den Elzen WPJ, Luben RN, Bremner AP, Gogakos A, Eastell R, Kearney PM, Hoff M, Le Blanc E, Ceresini G, Rivadeneira F, Uitterlinden AG, Khaw KT, Langhammer A, Stott DJ, Westendorp RGJ, Ferrucci L, Williams GR, Gussekloo J, Walsh JP, Aujesky D, Rodondi N | 2017-08-01 | The Journal of clinical endocrinology and metabolism | |
| Correction: The complex genetics of gait speed: genome-wide meta-analysis approach. | Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JD, Vered R, Deelen J, Arnold AM, Buchman AS, Tanaka T, Faul JD, Nethander M, Fornage M, Adams HH, Matteini AM, Callisaya ML, Smith AV, Yu L, De Jager PL, Evans DA, Gudnason V, Hofman A, Pattie A, Corley J, Launer LJ, Knopman DS, Parimi N, Turner ST, Bandinelli S, Beekman M, Gutman D, Sharvit L, Mooijaart SP, Liewald DC, Houwing-Duistermaat JJ, Ohlsson C, Moed M, Verlinden VJ, Mellström D, van der Geest JN, Karlsson M, Hernandez D, McWhirter R, Liu Y, Thomson R, Tranah GJ, Uitterlinden AG, Weir DR, Zhao W, Starr JM, Johnson AD, Ikram MA, Bennett DA, Cummings SR, Deary IJ, Harris TB, Kardia SLR, Mosley TH, Srikanth VK, Windham BG, Newman AB, Walston JD, Davies G, Evans DS, Slagboom EP, Ferrucci L, Kiel DP, Murabito JM, Atzmon G | 2017-07-01 | Aging | |
| Regret about the decision to start dialysis: a cross-sectional Dutch national survey. | Berkhout-Byrne N, Gaasbeek A, Mallat MJK, Rabelink TJ, Mooijaart SP, Dekker FW, van Buren M | 2017-07-01 | The Netherlands journal of medicine | |
| Secondary phenotype analysis in ascertained family designs: application to the Leiden longevity study. | Tissier R, Tsonaka R, Mooijaart SP, Slagboom E, Houwing-Duistermaat JJ | 2017-06-30 | ascertainment, family data, genetic association and heritability, mixed models, multivariate probit model | Statistics in medicine |
| Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism. | Stott DJ, Rodondi N, Kearney PM, Ford I, Westendorp RGJ, Mooijaart SP, Sattar N, Aubert CE, Aujesky D, Bauer DC, Baumgartner C, Blum MR, Browne JP, Byrne S, Collet TH, Dekkers OM, den Elzen WPJ, Du Puy RS, Ellis G, Feller M, Floriani C, Hendry K, Hurley C, Jukema JW, Kean S, Kelly M, Krebs D, Langhorne P, McCarthy G, McCarthy V, McConnachie A, McDade M, Messow M, O'Flynn A, O'Riordan D, Poortvliet RKE, Quinn TJ, Russell A, Sinnott C, Smit JWA, Van Dorland HA, Walsh KA, Walsh EK, Watt T, Wilson R, Gussekloo J | 2017-06-29 | The New England journal of medicine | |
| Validating the WHO maternal near miss tool: comparing high- and low-resource settings. | Witteveen T, Bezstarosti H, de Koning I, Nelissen E, Bloemenkamp KW, van Roosmalen J, van den Akker T | 2017-06-19 | Delivery, Maternal health, Maternal near miss, Maternal near miss-tool, Organ dysfunction, Resource setting comparison, Severe acute maternal morbidity, World health organization | BMC pregnancy and childbirth |
| Incidence, management and outcome of women requiring massive transfusion after childbirth in the Netherlands: secondary analysis of a nationwide cohort study between 2004 and 2006. | Ramler PI, van den Akker T, Henriquez DDCA, Zwart JJ, van Roosmalen J | 2017-06-19 | Blood transfusion, Maternal morbidity, Maternal mortality, Obstetrics, Postpartum hemorrhage | BMC pregnancy and childbirth |
| Thyroid Signaling, Insulin Resistance, and 2 Diabetes Mellitus: A Mendelian Randomization Study. | Bos MM, Smit RAJ, Trompet S, van Heemst D, Noordam R | 2017-06-01 | The Journal of clinical endocrinology and metabolism | |
| Physicians’ Knowledge of and Attitudes Toward Use of Opioids in Long-Term Care Facilities. | Griffioen C, Willems EG, Kouwenhoven SM, Caljouw MAA, Achterberg WP | 2017-06-01 | barriers, long-term care facilities, opioids, pain | Pain practice : the official journal of World Institute of Pain |
| Intellectual maturity and longevity: late-blooming composers and writers live longer than child prodigies. | Hafkamp MPJ, Slaets JPJ, van Bodegom D | 2017-05-30 | development, intellectual, life history theory, lifespan, longevity, maturity | Aging |
| Cognitive Testing in People at Increased Risk of Dementia Using a Smartphone App: The iVitality Proof-of-Principle Study. | Jongstra S, Wijsman LW, Cachucho R, Hoevenaar-Blom MP, Mooijaart SP, Richard E | 2017-05-25 | cognition, neuropsychological tests, telemedicine | JMIR mHealth and uHealth |
| Respectful maternity care in Ethiopian public health facilities. | Sheferaw ED, Bazant E, Gibson H, Fenta HB, Ayalew F, Belay TB, Worku MM, Kebebu AE, Woldie SA, Kim YM, van den Akker T, Stekelenburg J | 2017-05-16 | Birth companion, Birth positioning, Ethiopia, Health facility, Labor and delivery, Mistreatment of women, Respectful maternity care | Reproductive health |
| A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. | Noordam R, Sitlani CM, Avery CL, Stewart JD, Gogarten SM, Wiggins KL, Trompet S, Warren HR, Sun F, Evans DS, Li X, Li J, Smith AV, Bis JC, Brody JA, Busch EL, Caulfield MJ, Chen YI, Cummings SR, Cupples LA, Duan Q, Franco OH, Méndez-Giráldez R, Harris TB, Heckbert SR, van Heemst D, Hofman A, Floyd JS, Kors JA, Launer LJ, Li Y, Li-Gao R, Lange LA, Lin HJ, de Mutsert R, Napier MD, Newton-Cheh C, Poulter N, Reiner AP, Rice KM, Roach J, Rodriguez CJ, Rosendaal FR, Sattar N, Sever P, Seyerle AA, Slagboom PE, Soliman EZ, Sotoodehnia N, Stott DJ, Stürmer T, Taylor KD, Thornton TA, Uitterlinden AG, Wilhelmsen KC, Wilson JG, Gudnason V, Jukema JW, Laurie CC, Liu Y, Mook-Kanamori DO, Munroe PB, Rotter JI, Vasan RS, Psaty BM, Stricker BH, Whitsel EA | 2017-05-01 | Genome-wide, QT interval electrocardiography, RR interval, drug-gene interaction, tri/tetracyclic antidepressants | Journal of medical genetics |
| Temporal Relationship Between Cognitive and Physical Performance in Middle-Aged to Oldest Old People. | Stijntjes M, Aartsen MJ, Taekema DG, Gussekloo J, Huisman M, Meskers CGM, de Craen AJM, Maier AB | 2017-05-01 | Dynamic relationship, Executive function, Gait speed, Handgrip strength, Memory function | The journals of gerontology. Series A, Biological sciences and medical sciences |
| Successful Geriatric Rehabilitation: Effects on Patients’ Outcome of a National Program to Improve Quality of Care, the SINGER Study. | Holstege MS, Caljouw MAA, Zekveld IG, van Balen R, de Groot AJ, van Haastregt JCM, Schols JMGA, Hertogh CMPM, Gussekloo J, Achterberg WP | 2017-05-01 | Geriatric rehabilitation, discharge destination, independence in ADL, length of stay, quality of care, successful rehabilitation | Journal of the American Medical Directors Association |
| Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. | Justice AE, Winkler TW, Feitosa MF, Graff M, Fisher VA, Young K, Barata L, Deng X, Czajkowski J, Hadley D, Ngwa JS, Ahluwalia TS, Chu AY, Heard-Costa NL, Lim E, Perez J, Eicher JD, Kutalik Z, Xue L, Mahajan A, Renström F, Wu J, Qi Q, Ahmad S, Alfred T, Amin N, Bielak LF, Bonnefond A, Bragg J, Cadby G, Chittani M, Coggeshall S, Corre T, Direk N, Eriksson J, Fischer K, Gorski M, Neergaard Harder M, Horikoshi M, Huang T, Huffman JE, Jackson AU, Justesen JM, Kanoni S, Kinnunen L, Kleber ME, Komulainen P, Kumari M, Lim U, Luan J, Lyytikäinen LP, Mangino M, Manichaikul A, Marten J, Middelberg RPS, Müller-Nurasyid M, Navarro P, Pérusse L, Pervjakova N, Sarti C, Smith AV, Smith JA, Stančáková A, Strawbridge RJ, Stringham HM, Sung YJ, Tanaka T, Teumer A, Trompet S, van der Laan SW, van der Most PJ, Van Vliet-Ostaptchouk JV, Vedantam SL, Verweij N, Vink JM, Vitart V, Wu Y, Yengo L, Zhang W, Hua Zhao J, Zimmermann ME, Zubair N, Abecasis GR, Adair LS, Afaq S, Afzal U, Bakker SJL, Bartz TM, Beilby J, Bergman RN, Bergmann S, Biffar R, Blangero J, Boerwinkle E, Bonnycastle LL, Bottinger E, Braga D, Buckley BM, Buyske S, Campbell H, Chambers JC, Collins FS, Curran JE, de Borst GJ, de Craen AJM, de Geus EJC, Dedoussis G, Delgado GE, den Ruijter HM, Eiriksdottir G, Eriksson AL, Esko T, Faul JD, Ford I, Forrester T, Gertow K, Gigante B, Glorioso N, Gong J, Grallert H, Grammer TB, Grarup N, Haitjema S, Hallmans G, Hamsten A, Hansen T, Harris TB, Hartman CA, Hassinen M, Hastie ND, Heath AC, Hernandez D, Hindorff L, Hocking LJ, Hollensted M, Holmen OL, Homuth G, Jan Hottenga J, Huang J, Hung J, Hutri-Kähönen N, Ingelsson E, James AL, Jansson JO, Jarvelin MR, Jhun MA, Jørgensen ME, Juonala M, Kähönen M, Karlsson M, Koistinen HA, Kolcic I, Kolovou G, Kooperberg C, Krämer BK, Kuusisto J, Kvaløy K, Lakka TA, Langenberg C, Launer LJ, Leander K, Lee NR, Lind L, Lindgren CM, Linneberg A, Lobbens S, Loh M, Lorentzon M, Luben R, Lubke G, Ludolph-Donislawski A, Lupoli S, Madden PAF, Männikkö R, Marques-Vidal P, Martin NG, McKenzie CA, McKnight B, Mellström D, Menni C, Montgomery GW, Musk AB, Narisu N, Nauck M, Nolte IM, Oldehinkel AJ, Olden M, Ong KK, Padmanabhan S, Peyser PA, Pisinger C, Porteous DJ, Raitakari OT, Rankinen T, Rao DC, Rasmussen-Torvik LJ, Rawal R, Rice T, Ridker PM, Rose LM, Bien SA, Rudan I, Sanna S, Sarzynski MA, Sattar N, Savonen K, Schlessinger D, Scholtens S, Schurmann C, Scott RA, Sennblad B, Siemelink MA, Silbernagel G, Slagboom PE, Snieder H, Staessen JA, Stott DJ, Swertz MA, Swift AJ, Taylor KD, Tayo BO, Thorand B, Thuillier D, Tuomilehto J, Uitterlinden AG, Vandenput L, Vohl MC, Völzke H, Vonk JM, Waeber G, Waldenberger M, Westendorp RGJ, Wild S, Willemsen G, Wolffenbuttel BHR, Wong A, Wright AF, Zhao W, Zillikens MC, Baldassarre D, Balkau B, Bandinelli S, Böger CA, Boomsma DI, Bouchard C, Bruinenberg M, Chasman DI, Chen YD, Chines PS, Cooper RS, Cucca F, Cusi D, Faire U, Ferrucci L, Franks PW, Froguel P, Gordon-Larsen P, Grabe HJ, Gudnason V, Haiman CA, Hayward C, Hveem K, Johnson AD, Wouter Jukema J, Kardia SLR, Kivimaki M, Kooner JS, Kuh D, Laakso M, Lehtimäki T, Marchand LL, März W, McCarthy MI, Metspalu A, Morris AP, Ohlsson C, Palmer LJ, Pasterkamp G, Pedersen O, Peters A, Peters U, Polasek O, Psaty BM, Qi L, Rauramaa R, Smith BH, Sørensen TIA, Strauch K, Tiemeier H, Tremoli E, van der Harst P, Vestergaard H, Vollenweider P, Wareham NJ, Weir DR, Whitfield JB, Wilson JF, Tyrrell J, Frayling TM, Barroso I, Boehnke M, Deloukas P, Fox CS, Hirschhorn JN, Hunter DJ, Spector TD, Strachan DP, van Duijn CM, Heid IM, Mohlke KL, Marchini J, Loos RJF, Kilpeläinen TO, Liu CT, Borecki IB, North KE, Cupples LA | 2017-04-26 | Nature communications | |
| Variation in GP decisions on antihypertensive treatment in oldest-old and frail individuals across 29 countries. | Streit S, Verschoor M, Rodondi N, Bonfim D, Burman RA, Collins C, Biljana GK, Gintere S, Gómez Bravo R, Hoffmann K, Iftode C, Johansen KL, Kerse N, Koskela TH, Peštić SK, Kurpas D, Mallen CD, Maisoneuve H, Merlo C, Mueller Y, Muth C, Šter MP, Petrazzuoli F, Rosemann T, Sattler M, Švadlenková Z, Tatsioni A, Thulesius H, Tkachenko V, Torzsa P, Tsopra R, Canan T, Viegas RPA, Vinker S, de Waal MWM, Zeller A, Gussekloo J, Poortvliet RKE | 2017-04-20 | Clinical variation, Elderly, Frailty, General practitioners, Hypertension, Oldest-old | BMC geriatrics |
| Vascular Cognitive Impairment in a Memory Clinic Population: Rationale and Design of the “Utrecht-Amsterdam Clinical Features and Prognosis in Vascular Cognitive Impairment” (TRACE-VCI) Study. | Boomsma JMF, Exalto LG, Barkhof F, van den Berg E, de Bresser J, Heinen R, Koek HL, Prins ND, Scheltens P, Weinstein HC, van der Flier WM, Biessels GJ | 2017-04-19 | dementia, memory clinic, prognosis, small vessel disease, vascular cognitive impairment, vascular disease | JMIR research protocols |
| Short telomere length is associated with impaired cognitive performance in European ancestry cohorts. | Hägg S, Zhan Y, Karlsson R, Gerritsen L, Ploner A, van der Lee SJ, Broer L, Deelen J, Marioni RE, Wong A, Lundquist A, Zhu G, Hansell NK, Sillanpää E, Fedko IO, Amin NA, Beekman M, de Craen AJM, Degerman S, Harris SE, Kan KJ, Martin-Ruiz CM, Montgomery GW, Adolfsson AN, Reynolds CA, Samani NJ, Suchiman HED, Viljanen A, von Zglinicki T, Wright MJ, Hottenga JJ, Boomsma DI, Rantanen T, Kaprio JA, Nyholt DR, Martin NG, Nyberg L, Adolfsson R, Kuh D, Starr JM, Deary IJ, Slagboom PE, van Duijn CM, Codd V, Pedersen NL | 2017-04-18 | Translational psychiatry | |
| Phenotypic screening of cannabinoid receptor 2 ligands shows different sensitivity to genotype. | Hillger JM, le Roy B, Wang Z, Mulder-Krieger T, Boomsma DI, Slagboom PE, Danen EHJ, IJzerman AP, Heitman LH | 2017-04-15 | 2-AG (PubMed CID: 5282280), AEA (PubMed CID: 5281969), AM251 (PubMed CID: 2125), AM630 (PubMed CID: 4302963), BAY59-3074 (PubMed CID: 10479060), CP55940 (PubMed CID: 10479060), Cannabinoid receptor 2, GW405833 (PubMed CID: 46916568), JWH133 (PubMed CID: 6918505), Label-free, Lymphoblastoid cell lines, Precision medicine, Single Nucleotide Polymorphism, WIN55212-2 (PubMed CID: 5311501) | Biochemical pharmacology |
| Thyroid Status and Mortality Risk in Older Adults With Normal Thyrotropin: Sex Differences in the Milan Geriatrics 75+ Cohort Study. | Ogliari G, Smit RA, van der Spoel E, Mari D, Torresani E, Felicetta I, Lucchi TA, Rossi PD, van Heemst D, de Craen AJ, Westendorp RG | 2017-04-01 | Geriatric cohort, Longevity, Thyrotropin, Thyroxine | The journals of gerontology. Series A, Biological sciences and medical sciences |
| Familial longevity is characterized by high circadian rhythmicity of serum cholesterol in healthy elderly individuals. | van den Berg R, Noordam R, Kooijman S, Jansen SWM, Akintola AA, Slagboom PE, Pijl H, Rensen PCN, Biermasz NR, van Heemst D | 2017-04-01 | aging, biological clock, cholesterol, circadian rhythm, longevity | Aging cell |
| Validity of the three apathy items of the Geriatric Depression Scale (GDS-3A) in measuring apathy in older persons. | Bertens AS, Moonen JE, de Waal MW, Foster-Dingley JC, de Ruijter W, Gussekloo J, van der Mast RC, de Craen AJ | 2017-04-01 | Apathy Scale, Geriatric Depression Scale-3A (GDS-3A), apathy, older persons, validity | International journal of geriatric psychiatry |
| A multi-component cognitive behavioural intervention for the treatment of fear of falling after hip fracture (FIT-HIP): protocol of a randomised controlled trial. | Scheffers-Barnhoorn MN, van Haastregt JC, Schols JM, Kempen GI, van Balen R, Visschedijk JH, van den Hout WB, Dumas EM, Achterberg WP, van Eijk M | 2017-03-20 | Cognitive behavioural therapy, Fear of falling, Geriatric rehabilitation, Hip fracture, Randomised controlled trial | BMC geriatrics |
| Effect of intranasally administered insulin on cerebral blood flow and perfusion; a randomized experiment in young and older adults. | Akintola AA, van Opstal AM, Westendorp RG, Postmus I, van der Grond J, van Heemst D | 2017-03-14 | aging, cerebral blood flow, continuous arterial spin labelling (CASL), intranasal insulin, magnetic resonance imaging (MRI), phase contrast MR angiography | Aging |
| Prolonged high-fat diet induces gradual and fat depot-specific DNA methylation changes in adult mice. | Zwamborn RA, Slieker RC, Mulder PC, Zoetemelk I, Verschuren L, Suchiman HE, Toet KH, Droog S, Slagboom PE, Kooistra T, Kleemann R, Heijmans BT | 2017-03-03 | Scientific reports | |
| Measurement properties of the EQ-5D across four major geriatric conditions: Findings from TOPICS-MDS. | Lutomski JE, Krabbe PF, Bleijenberg N, Blom J, Kempen GI, MacNeil-Vroomen J, Muntinga ME, Steyerburg E, Olde-Rikkert MG, Melis RJ | 2017-03-03 | Dizziness, EQ-5D, Hearing loss, Joint diseases, Quality of life, Urinary incontinence | Health and quality of life outcomes |
| Care-Related Quality of Life of Informal Caregivers After Geriatric Rehabilitation. | van Dam PH, Achterberg WP, Caljouw MA | 2017-03-01 | Care-related quality of life, CarerQoL, geriatric rehabilitation, informal care, skilled nursing facility | Journal of the American Medical Directors Association |
| Study protocol; Thyroid hormone Replacement for Untreated older adults with Subclinical hypothyroidism – a randomised placebo controlled Trial (TRUST). | Stott DJ, Gussekloo J, Kearney PM, Rodondi N, Westendorp RG, Mooijaart S, Kean S, Quinn TJ, Sattar N, Hendry K, Du Puy R, Den Elzen WP, Poortvliet RK, Smit JW, Jukema JW, Dekkers OM, Blum M, Collet TH, McCarthy V, Hurley C, Byrne S, Browne J, Watt T, Bauer D, Ford I | 2017-02-03 | Elderly, Levothyroxine, Quality of life, Randomised controlled trial, Subclinical hypothyroidism, Thyroid disease | BMC endocrine disorders |
| Human Plasma N-glycosylation as Analyzed by Matrix-Assisted Laser Desorption/Ionization-Fourier Transform Ion Cyclotron Resonance-MS Associates with Markers of Inflammation and Metabolic Health. | Reiding KR, Ruhaak LR, Uh HW, El Bouhaddani S, van den Akker EB, Plomp R, McDonnell LA, Houwing-Duistermaat JJ, Slagboom PE, Beekman M, Wuhrer M | 2017-02-01 | Molecular & cellular proteomics : MCP | |
| A framework for the detection of de novo mutations in family-based sequencing data. | Francioli LC, Cretu-Stancu M, Garimella KV, Fromer M, Kloosterman WP, Samocha KE, Neale BM, Daly MJ, Banks E, DePristo MA, de Bakker PI | 2017-02-01 | European journal of human genetics : EJHG | |
| Complement receptor 1 gene polymorphisms are associated with cardiovascular risk. | de Vries MA, Trompet S, Mooijaart SP, Smit RA, Böhringer S, Castro Cabezas M, Jukema JW | 2017-02-01 | Apolipoprotein B, Atherosclerosis, C-reactive protein, Inflammation, Myocardial infarction | Atherosclerosis |
| Predicting Risk of Cognitive Decline in Very Old Adults Using Three Models: The Framingham Stroke Risk Profile; the Cardiovascular Risk Factors, Aging, and Dementia Model; and Oxi-Inflammatory Biomarkers. | Harrison SL, de Craen AJ, Kerse N, Teh R, Granic A, Davies K, Wesnes KA, den Elzen WP, Gussekloo J, Kirkwood TB, Robinson L, Jagger C, Siervo M, Stephan BC | 2017-02-01 | biomarkers, cardiovascular risk, cognitive decline, cognitive function, dementia | Journal of the American Geriatrics Society |
| The complex genetics of gait speed: genome-wide meta-analysis approach. | Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JD, Vered R, Deelen J, Arnold AM, Buchman AS, Tanaka T, Faul JD, Nethander M, Fornage M, Adams HH, Matteini AM, Callisaya ML, Smith AV, Yu L, De Jager PL, Evans DA, Gudnason V, Hofman A, Pattie A, Corley J, Launer LJ, Knopman DS, Parimi N, Turner ST, Bandinelli S, Beekman M, Gutman D, Sharvit L, Mooijaart SP, Liewald DC, Houwing-Duistermaat JJ, Ohlsson C, Moed M, Verlinden VJ, Mellström D, van der Geest JN, Karlsson M, Hernandez D, McWhirter R, Liu Y, Thomson R, Tranah GJ, Uitterlinden AG, Weir DR, Zhao W, Starr JM, Johnson AD, Ikram MA, Bennett DA, Cummings SR, Deary IJ, Harris TB, Kardia SL, Mosley TH, Srikanth VK, Windham BG, Newman AB, Walston JD, Davies G, Evans DS, Slagboom EP, Ferrucci L, Kiel DP, Murabito JM, Atzmon G | 2017-01-10 | GWAS, aging, gait speed, meta-analysis | Aging |
| Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity. | Wahl S, Drong A, Lehne B, Loh M, Scott WR, Kunze S, Tsai PC, Ried JS, Zhang W, Yang Y, Tan S, Fiorito G, Franke L, Guarrera S, Kasela S, Kriebel J, Richmond RC, Adamo M, Afzal U, Ala-Korpela M, Albetti B, Ammerpohl O, Apperley JF, Beekman M, Bertazzi PA, Black SL, Blancher C, Bonder MJ, Brosch M, Carstensen-Kirberg M, de Craen AJ, de Lusignan S, Dehghan A, Elkalaawy M, Fischer K, Franco OH, Gaunt TR, Hampe J, Hashemi M, Isaacs A, Jenkinson A, Jha S, Kato N, Krogh V, Laffan M, Meisinger C, Meitinger T, Mok ZY, Motta V, Ng HK, Nikolakopoulou Z, Nteliopoulos G, Panico S, Pervjakova N, Prokisch H, Rathmann W, Roden M, Rota F, Rozario MA, Sandling JK, Schafmayer C, Schramm K, Siebert R, Slagboom PE, Soininen P, Stolk L, Strauch K, Tai ES, Tarantini L, Thorand B, Tigchelaar EF, Tumino R, Uitterlinden AG, van Duijn C, van Meurs JB, Vineis P, Wickremasinghe AR, Wijmenga C, Yang TP, Yuan W, Zhernakova A, Batterham RL, Smith GD, Deloukas P, Heijmans BT, Herder C, Hofman A, Lindgren CM, Milani L, van der Harst P, Peters A, Illig T, Relton CL, Waldenberger M, Järvelin MR, Bollati V, Soong R, Spector TD, Scott J, McCarthy MI, Elliott P, Bell JT, Matullo G, Gieger C, Kooner JS, Grallert H, Chambers JC | 2017-01-05 | Nature | |
| Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. | van Rooij FJA, Qayyum R, Smith AV, Zhou Y, Trompet S, Tanaka T, Keller MF, Chang LC, Schmidt H, Yang ML, Chen MH, Hayes J, Johnson AD, Yanek LR, Mueller C, Lange L, Floyd JS, Ghanbari M, Zonderman AB, Jukema JW, Hofman A, van Duijn CM, Desch KC, Saba Y, Ozel AB, Snively BM, Wu JY, Schmidt R, Fornage M, Klein RJ, Fox CS, Matsuda K, Kamatani N, Wild PS, Stott DJ, Ford I, Slagboom PE, Yang J, Chu AY, Lambert AJ, Uitterlinden AG, Franco OH, Hofer E, Ginsburg D, Hu B, Keating B, Schick UM, Brody JA, Li JZ, Chen Z, Zeller T, Guralnik JM, Chasman DI, Peters LL, Kubo M, Becker DM, Li J, Eiriksdottir G, Rotter JI, Levy D, Grossmann V, Patel KV, Chen CH, Ridker PM, Tang H, Launer LJ, Rice KM, Li-Gao R, Ferrucci L, Evans MK, Choudhuri A, Trompouki E, Abraham BJ, Yang S, Takahashi A, Kamatani Y, Kooperberg C, Harris TB, Jee SH, Coresh J, Tsai FJ, Longo DL, Chen YT, Felix JF, Yang Q, Psaty BM, Boerwinkle E, Becker LC, Mook-Kanamori DO, Wilson JG, Gudnason V, O'Donnell CJ, Dehghan A, Cupples LA, Nalls MA, Morris AP, Okada Y, Reiner AP, Zon LI, Ganesh SK | 2017-01-05 | American journal of human genetics | |
| Assessment of health status by molecular measures in adults ranging from middle-aged to old: Ready for clinical use? | Waaijer ME, Westendorp RG, Goldeck D, Gunn DA, Pawelec G, Stijntjes M, Slagboom PE, Maier AB | 2017-01-01 | Aging, CD57, Functional capacity, Immunosenescence, Senescence, p16INK4a | Experimental gerontology |
| Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study. | de Vries PS, Sabater-Lleal M, Chasman DI, Trompet S, Ahluwalia TS, Teumer A, Kleber ME, Chen MH, Wang JJ, Attia JR, Marioni RE, Steri M, Weng LC, Pool R, Grossmann V, Brody JA, Venturini C, Tanaka T, Rose LM, Oldmeadow C, Mazur J, Basu S, Frånberg M, Yang Q, Ligthart S, Hottenga JJ, Rumley A, Mulas A, de Craen AJ, Grotevendt A, Taylor KD, Delgado GE, Kifley A, Lopez LM, Berentzen TL, Mangino M, Bandinelli S, Morrison AC, Hamsten A, Tofler G, de Maat MP, Draisma HH, Lowe GD, Zoledziewska M, Sattar N, Lackner KJ, Völker U, McKnight B, Huang J, Holliday EG, McEvoy MA, Starr JM, Hysi PG, Hernandez DG, Guan W, Rivadeneira F, McArdle WL, Slagboom PE, Zeller T, Psaty BM, Uitterlinden AG, de Geus EJ, Stott DJ, Binder H, Hofman A, Franco OH, Rotter JI, Ferrucci L, Spector TD, Deary IJ, März W, Greinacher A, Wild PS, Cucca F, Boomsma DI, Watkins H, Tang W, Ridker PM, Jukema JW, Scott RJ, Mitchell P, Hansen T, O'Donnell CJ, Smith NL, Strachan DP, Dehghan A | 2017-01-01 | PloS one | |
| Identification of context-dependent expression quantitative trait loci in whole blood. | Zhernakova DV, Deelen P, Vermaat M, van Iterson M, van Galen M, Arindrarto W, van 't Hof P, Mei H, van Dijk F, Westra HJ, Bonder MJ, van Rooij J, Verkerk M, Jhamai PM, Moed M, Kielbasa SM, Bot J, Nooren I, Pool R, van Dongen J, Hottenga JJ, Stehouwer CD, van der Kallen CJ, Schalkwijk CG, Zhernakova A, Li Y, Tigchelaar EF, de Klein N, Beekman M, Deelen J, van Heemst D, van den Berg LH, Hofman A, Uitterlinden AG, van Greevenbroek MM, Veldink JH, Boomsma DI, van Duijn CM, Wijmenga C, Slagboom PE, Swertz MA, Isaacs A, van Meurs JB, Jansen R, Heijmans BT, 't Hoen PA, Franke L | 2017-01-01 | Nature genetics | |
| Disease variants alter transcription factor levels and methylation of their binding sites. | Bonder MJ, Luijk R, Zhernakova DV, Moed M, Deelen P, Vermaat M, van Iterson M, van Dijk F, van Galen M, Bot J, Slieker RC, Jhamai PM, Verbiest M, Suchiman HE, Verkerk M, van der Breggen R, van Rooij J, Lakenberg N, Arindrarto W, Kielbasa SM, Jonkers I, van 't Hof P, Nooren I, Beekman M, Deelen J, van Heemst D, Zhernakova A, Tigchelaar EF, Swertz MA, Hofman A, Uitterlinden AG, Pool R, van Dongen J, Hottenga JJ, Stehouwer CD, van der Kallen CJ, Schalkwijk CG, van den Berg LH, van Zwet EW, Mei H, Li Y, Lemire M, Hudson TJ, Slagboom PE, Wijmenga C, Veldink JH, van Greevenbroek MM, van Duijn CM, Boomsma DI, Isaacs A, Jansen R, van Meurs JB, 't Hoen PA, Franke L, Heijmans BT | 2017-01-01 | Nature genetics | |
| Left Ventricular Hypertrophy and Cognitive Decline in Old Age. | Mahinrad S, Vriend AE, Jukema JW, van Heemst D, Sattar N, Blauw GJ, Macfarlane PW, Clark EN, de Craen AJM, Sabayan B | 2017-01-01 | Cardiovascular disease, cognitive function, elderly, left ventricular hypertrophy | Journal of Alzheimer's disease : JAD |
| Poor sleep quality and later sleep timing are risk factors for osteopenia and sarcopenia in middle-aged men and women: The NEO study. | Lucassen EA, de Mutsert R, le Cessie S, Appelman-Dijkstra NM, Rosendaal FR, van Heemst D, den Heijer M, Biermasz NR | 2017-01-01 | PloS one | |
| Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes. | Mandaviya PR, Joehanes R, Aïssi D, Kühnel B, Marioni RE, Truong V, Stolk L, Beekman M, Bonder MJ, Franke L, Gieger C, Huan T, Ikram MA, Kunze S, Liang L, Lindemans J, Liu C, McRae AF, Mendelson MM, Müller-Nurasyid M, Peters A, Slagboom PE, Starr JM, Trégouët DA, Uitterlinden AG, van Greevenbroek MMJ, van Heemst D, van Iterson M, Wells PS, Yao C, Deary IJ, Gagnon F, Heijmans BT, Levy D, Morange PE, Waldenberger M, Heil SG, van Meurs JBJ | 2017-01-01 | PloS one | |
| The effect of tranexamic acid on blood loss and maternal outcome in the treatment of persistent postpartum hemorrhage: A nationwide retrospective cohort study. | Gillissen A, Henriquez DDCA, van den Akker T, Caram-Deelder C, Wind M, Zwart JJ, van Roosmalen J, Eikenboom J, Bloemenkamp KWM, van der Bom JG | 2017-01-01 | PloS one | |
| Functional and cognitive impairment, social environment, frailty and adverse health outcomes in older patients with head and neck cancer, a systematic review. | van Deudekom FJ, Schimberg AS, Kallenberg MH, Slingerland M, van der Velden LA, Mooijaart SP | 2017-01-01 | Cognitive impairment, Frailty, Functional impairment, Head and neck cancer, Mood, Social environment, Systematic review | Oral oncology |
| External validity of randomized controlled trials in older adults, a systematic review. | van Deudekom FJ, Postmus I, van der Ham DJ, Pothof AB, Broekhuizen K, Blauw GJ, Mooijaart SP | 2017-01-01 | PloS one | |
| High Liver Enzyme Concentrations are Associated with Higher Glycemia, but not with Glycemic Variability, in Individuals without Diabetes Mellitus. | Noordam R, Vermond D, Drenth H, Wijman CA, Akintola AA, van der Kroef S, Jansen SWM, Huurman NC, Schutte BAM, Beekman M, Slagboom PE, Mooijaart SP, van Heemst D | 2017-01-01 | continuous glucose monitoring, cross-sectional cohort study, glycemia, glycemic variability, liver enzymes | Frontiers in endocrinology |
| High Sensitivity Cardiac Troponin T and Cognitive Function in the Oldest Old: The Leiden 85-Plus Study. | Bertens AS, Sabayan B, de Craen AJM, Van der Mast RC, Gussekloo J | 2017-01-01 | Cardiac disease, cognitive function, high sensitivity cardiac troponin T, oldest old | Journal of Alzheimer's disease : JAD |
| Lower Performance in Orientation to Time and Place Associates with Greater Risk of Cardiovascular Events and Mortality in the Oldest Old: Leiden 85-Plus Study. | Rostamian S, van Buchem MA, Jukema JW, Gussekloo J, Poortvliet RKE, de Cren AJM, Sabayan B | 2017-01-01 | mortality, myocardial infarction, oldest old, orientation to place, orientation to time, stroke | Frontiers in aging neuroscience |
| A Structured Process Description of a Pragmatic Implementation Project: Improving Integrated Care for Older Persons in Residential Care Homes. | Poot AJ, de Waard CS, Wind AW, Caljouw MAA, Gussekloo J | 2017-01-01 | delivery of health care, frail elderly, health services research, homes for the aged, implementation, integrated, integrated care, older persons, pragmatic, process description | Inquiry : a journal of medical care organization, provision and financing |
| Prevalence of the Use of Opioids for Treatment of Pain in Persons with a Cognitive Impairment Compared with Cognitively Intact Persons: A Systematic Review. | Griffioen C, Willems EG, Husebo BS, Achterberg WP | 2017-01-01 | Cognitive impairment, cancer, dementia, opioids, pain | Current Alzheimer research |
| The Effect of Music Therapy in Patients with Huntington’s Disease: A Randomized Controlled Trial. | van Bruggen-Rufi MC, Vink AC, Wolterbeek R, Achterberg WP, Roos RA | 2017-01-01 | Behavior, Huntington’s disease, RCT, communication, music therapy, quality of life | Journal of Huntington's disease |
| [Timing of the care internship in the medical curriculum; when should students make acquaintance with older patients?]. | Achterberg WP, Lindenberg J | 2017-01-01 | Nederlands tijdschrift voor geneeskunde | |
| The effect of standardized food intake on the association between BMI and 1H-NMR metabolites. | Schutte BAM, van den Akker EB, Deelen J, van de Rest O, van Heemst D, Feskens EJM, Beekman M, Slagboom PE | 2016-12-14 | Scientific reports | |
| Meta-analysis of genome-wide association studies of HDL cholesterol response to statins. | Postmus I, Warren HR, Trompet S, Arsenault BJ, Avery CL, Bis JC, Chasman DI, de Keyser CE, Deshmukh HA, Evans DS, Feng Q, Li X, Smit RA, Smith AV, Sun F, Taylor KD, Arnold AM, Barnes MR, Barratt BJ, Betteridge J, Boekholdt SM, Boerwinkle E, Buckley BM, Chen YI, de Craen AJ, Cummings SR, Denny JC, Dubé MP, Durrington PN, Eiriksdottir G, Ford I, Guo X, Harris TB, Heckbert SR, Hofman A, Hovingh GK, Kastelein JJ, Launer LJ, Liu CT, Liu Y, Lumley T, McKeigue PM, Munroe PB, Neil A, Nickerson DA, Nyberg F, O'Brien E, O'Donnell CJ, Post W, Poulter N, Vasan RS, Rice K, Rich SS, Rivadeneira F, Sattar N, Sever P, Shaw-Hawkins S, Shields DC, Slagboom PE, Smith NL, Smith JD, Sotoodehnia N, Stanton A, Stott DJ, Stricker BH, Stürmer T, Uitterlinden AG, Wei WQ, Westendorp RG, Whitsel EA, Wiggins KL, Wilke RA, Ballantyne CM, Colhoun HM, Cupples LA, Franco OH, Gudnason V, Hitman G, Palmer CN, Psaty BM, Ridker PM, Stafford JM, Stein CM, Tardif JC, Caulfield MJ, Jukema JW, Rotter JI, Krauss RM | 2016-12-01 | Genome-wide association study, HDL-cholesterol, Statins, pharmacogenetics | Journal of medical genetics |
| Growth hormone secretion is diminished and tightly controlled in humans enriched for familial longevity. | van der Spoel E, Jansen SW, Akintola AA, Ballieux BE, Cobbaert CM, Slagboom PE, Blauw GJ, Westendorp RGJ, Pijl H, Roelfsema F, van Heemst D | 2016-12-01 | IGF-1, approximate entropy, familial longevity, growth hormone, hormone secretion, human | Aging cell |
| Assessment of causality between serum gamma-glutamyltransferase and type 2 diabetes mellitus using publicly available data: a Mendelian randomization study. | Noordam R, Smit RA, Postmus I, Trompet S, van Heemst D | 2016-12-01 | Gamma-glutamyltransferase, Mendelian randomization, type 2 diabetes mellitus | International journal of epidemiology |
| Prevalence, Indications, Risk Indicators, and Outcomes of Emergency Peripartum Hysterectomy Worldwide: A Systematic Review and Meta-analysis. | van den Akker T, Brobbel C, Dekkers OM, Bloemenkamp KWM | 2016-12-01 | Obstetrics and gynecology | |
| Subclinical Thyroid Dysfunction and the Risk of Cognitive Decline: a Meta-Analysis of Prospective Cohort Studies. | Rieben C, Segna D, da Costa BR, Collet TH, Chaker L, Aubert CE, Baumgartner C, Almeida OP, Hogervorst E, Trompet S, Masaki K, Mooijaart SP, Gussekloo J, Peeters RP, Bauer DC, Aujesky D, Rodondi N | 2016-12-01 | The Journal of clinical endocrinology and metabolism | |
| [Coping strategies of older people with low mood]. | von Faber M, van der Weele GM, van der Geest G, Blom JW, van der Zouwe N, Reis R, van der Mast RC, Gussekloo J | 2016-12-01 | Depressive symptoms, Interventions, Low mood, Older people | Tijdschrift voor gerontologie en geriatrie |
| [Education within the Dutch National Care for the Elderly Programme]. | Oeseburg B, Schols J, Olde Rikkert M, van der Horst H, Smilde-van den Doel D, de Rooij S, Buurman-van Es B, Schuurmans M, Gussekloo J | 2016-12-01 | Care, Healthcare, Housing, Older people education, Quality of life, Social care | Tijdschrift voor gerontologie en geriatrie |
| The association of thyroid function and the risk of kidney function decline: a population-based cohort study. | Chaker L, Sedaghat S, Hoorn EJ, Elzen WP, Gussekloo J, Hofman A, Ikram MA, Franco OH, Dehghan A, Peeters RP | 2016-12-01 | European journal of endocrinology | |
| Structured scoring of supporting nursing tasks to enhance early discharge in geriatric rehabilitation: The BACK-HOME quasi-experimental study. | Holstege MS, Bakkers E, van Balen R, Gussekloo J, Achterberg WP, Caljouw MA | 2016-12-01 | Early discharge, Geriatric rehabilitation, Nursing support scorecard, Nursing tasks | International journal of nursing studies |
| HSP90 inhibition overcomes ibrutinib resistance in mantle cell lymphoma. | Jacobson C, Kopp N, Layer JV, Redd RA, Tschuri S, Haebe S, van Bodegom D, Bird L, Christie AL, Christodoulou A, Saur A, Tivey T, Zapf S, Bararia D, Zimber-Strobl U, Rodig SJ, Weigert O, Weinstock DM | 2016-11-24 | Blood | |
| Measuring senescence rates of patients with end-stage renal disease while accounting for population heterogeneity: an analysis of data from the ERA-EDTA Registry. | Koopman JJ, Kramer A, van Heemst D, Åsberg A, Beuscart JB, Buturović-Ponikvar J, Collart F, Couchoud CG, Finne P, Heaf JG, Massy ZA, De Meester JM, Palsson R, Steenkamp R, Traynor JP, Jager KJ, Putter H | 2016-11-01 | Aging, Dialysis, End-stage renal disease, Frailty, Gompertz model, Kidney transplantation, Mortality rate, Population heterogeneity, Senescence, Senescence rate | Annals of epidemiology |
| Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis. | Chaker L, Baumgartner C, den Elzen WP, Collet TH, Ikram MA, Blum MR, Dehghan A, Drechsler C, Luben RN, Portegies ML, Iervasi G, Medici M, Stott DJ, Dullaart RP, Ford I, Bremner A, Newman AB, Wanner C, Sgarbi JA, Dörr M, Longstreth WT, Psaty BM, Ferrucci L, Maciel RM, Westendorp RG, Jukema JW, Ceresini G, Imaizumi M, Hofman A, Bakker SJ, Franklyn JA, Khaw KT, Bauer DC, Walsh JP, Razvi S, Gussekloo J, Völzke H, Franco OH, Cappola AR, Rodondi N, Peeters RP | 2016-11-01 | The Journal of clinical endocrinology and metabolism | |
| Assessment of Comorbidity Burden and its Association With Functional Rehabilitation Outcome After Stroke or Hip Fracture: A Systematic Review and Meta-Analysis. | Kabboord AD, van Eijk M, Fiocco M, van Balen R, Achterberg WP | 2016-11-01 | Comorbidity, functional prognosis, rehabilitation, strokehip fracture | Journal of the American Medical Directors Association |
| Maternal Near Miss and quality of care in a rural Rwandan hospital. | Kalisa R, Rulisa S, van den Akker T, van Roosmalen J | 2016-10-21 | Audit, Maternal morbidity, Maternal mortality, Maternal near miss, Obstetrics, Quality of care | BMC pregnancy and childbirth |
| A high-quality human reference panel reveals the complexity and distribution of genomic structural variants. | Hehir-Kwa JY, Marschall T, Kloosterman WP, Francioli LC, Baaijens JA, Dijkstra LJ, Abdellaoui A, Koval V, Thung DT, Wardenaar R, Renkens I, Coe BP, Deelen P, de Ligt J, Lameijer EW, van Dijk F, Hormozdiari F, Uitterlinden AG, van Duijn CM, Eichler EE, de Bakker PI, Swertz MA, Wijmenga C, van Ommen GB, Slagboom PE, Boomsma DI, Schönhuth A, Ye K, Guryev V | 2016-10-06 | Nature communications | |
| A reference panel of 64,976 haplotypes for genotype imputation. | McCarthy S, Das S, Kretzschmar W, Delaneau O, Wood AR, Teumer A, Kang HM, Fuchsberger C, Danecek P, Sharp K, Luo Y, Sidore C, Kwong A, Timpson N, Koskinen S, Vrieze S, Scott LJ, Zhang H, Mahajan A, Veldink J, Peters U, Pato C, van Duijn CM, Gillies CE, Gandin I, Mezzavilla M, Gilly A, Cocca M, Traglia M, Angius A, Barrett JC, Boomsma D, Branham K, Breen G, Brummett CM, Busonero F, Campbell H, Chan A, Chen S, Chew E, Collins FS, Corbin LJ, Smith GD, Dedoussis G, Dorr M, Farmaki AE, Ferrucci L, Forer L, Fraser RM, Gabriel S, Levy S, Groop L, Harrison T, Hattersley A, Holmen OL, Hveem K, Kretzler M, Lee JC, McGue M, Meitinger T, Melzer D, Min JL, Mohlke KL, Vincent JB, Nauck M, Nickerson D, Palotie A, Pato M, Pirastu N, McInnis M, Richards JB, Sala C, Salomaa V, Schlessinger D, Schoenherr S, Slagboom PE, Small K, Spector T, Stambolian D, Tuke M, Tuomilehto J, Van den Berg LH, Van Rheenen W, Volker U, Wijmenga C, Toniolo D, Zeggini E, Gasparini P, Sampson MG, Wilson JF, Frayling T, de Bakker PI, Swertz MA, McCarroll S, Kooperberg C, Dekker A, Altshuler D, Willer C, Iacono W, Ripatti S, Soranzo N, Walter K, Swaroop A, Cucca F, Anderson CA, Myers RM, Boehnke M, McCarthy MI, Durbin R | 2016-10-01 | Nature genetics | |
| Both low circulating insulin-like growth factor-1 and high-density lipoprotein cholesterol are associated with hair loss in middle-aged women. | Noordam R, Gunn DA, van Drielen K, Westgate G, Slagboom PE, de Craen AJ, van Heemst D | 2016-10-01 | The British journal of dermatology | |
| Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. | Teumer A, Qi Q, Nethander M, Aschard H, Bandinelli S, Beekman M, Berndt SI, Bidlingmaier M, Broer L, Cappola A, Ceda GP, Chanock S, Chen MH, Chen TC, Chen YD, Chung J, Del Greco Miglianico F, Eriksson J, Ferrucci L, Friedrich N, Gnewuch C, Goodarzi MO, Grarup N, Guo T, Hammer E, Hayes RB, Hicks AA, Hofman A, Houwing-Duistermaat JJ, Hu F, Hunter DJ, Husemoen LL, Isaacs A, Jacobs KB, Janssen JA, Jansson JO, Jehmlich N, Johnson S, Juul A, Karlsson M, Kilpelainen TO, Kovacs P, Kraft P, Li C, Linneberg A, Liu Y, Loos RJ, Lorentzon M, Lu Y, Maggio M, Magi R, Meigs J, Mellström D, Nauck M, Newman AB, Pollak MN, Pramstaller PP, Prokopenko I, Psaty BM, Reincke M, Rimm EB, Rotter JI, Saint Pierre A, Schurmann C, Seshadri S, Sjögren K, Slagboom PE, Strickler HD, Stumvoll M, Suh Y, Sun Q, Zhang C, Svensson J, Tanaka T, Tare A, Tönjes A, Uh HW, van Duijn CM, van Heemst D, Vandenput L, Vasan RS, Völker U, Willems SM, Ohlsson C, Wallaschofski H, Kaplan RC | 2016-10-01 | IGF-I, IGFBP-3, aging, genomewide association study, growth hormone axis, longevity | Aging cell |
| Predicting adverse health outcomes in older emergency department patients: the APOP study. | de Gelder J, Lucke JA, de Groot B, Fogteloo AJ, Anten S, Mesri K, Steyerberg EW, Heringhaus C, Blauw GJ, Mooijaart SP | 2016-10-01 | The Netherlands journal of medicine | |
| Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms. | Slieker RC, van Iterson M, Luijk R, Beekman M, Zhernakova DV, Moed MH, Mei H, van Galen M, Deelen P, Bonder MJ, Zhernakova A, Uitterlinden AG, Tigchelaar EF, Stehouwer CD, Schalkwijk CG, van der Kallen CJ, Hofman A, van Heemst D, de Geus EJ, van Dongen J, Deelen J, van den Berg LH, van Meurs J, Jansen R, 't Hoen PA, Franke L, Wijmenga C, Veldink JH, Swertz MA, van Greevenbroek MM, van Duijn CM, Boomsma DI, Slagboom PE, Heijmans BT | 2016-09-22 | 450k, Ageing, DNA damage, DNA methylation, Variability | Genome biology |
| Functional and Cognitive Impairment, Frailty, and Adverse Health Outcomes in Older Patients Reaching ESRD-A Systematic Review. | Kallenberg MH, Kleinveld HA, Dekker FW, van Munster BC, Rabelink TJ, van Buren M, Mooijaart SP | 2016-09-07 | Cognition Disorders, Follow-Up Studies, Humans, Kidney Failure, Chronic, Outcome Assessment (Health Care), Renal Replacement Therapy, cognitive impairment, dialysis, end stage renal disease, frail elderly, functional impairment, renal dialysis | Clinical journal of the American Society of Nephrology : CJASN |
| Cortical phase changes measured using 7-T MRI in subjects with subjective cognitive impairment, and their association with cognitive function. | van Rooden S, Buijs M, van Vliet ME, Versluis MJ, Webb AG, Oleksik AM, van de Wiel L, Middelkoop HA, Blauw GJ, Weverling-Rynsburger AW, Goos JD, van der Flier WM, Koene T, Scheltens P, Barkhof F, van de Rest O, Slagboom PE, van Buchem MA, van der Grond J | 2016-09-01 | AD pathology, Alzheimer's disease, brain imaging, cognition, human 7-T MRI, phase, subjective cognitive impairment | NMR in biomedicine |
| Getting personal: Endogenous adenosine receptor signaling in lymphoblastoid cell lines. | Hillger JM, Diehl C, van Spronsen E, Boomsma DI, Slagboom PE, Heitman LH, IJzerman AP | 2016-09-01 | Adenosine (PubChem CID: 60961), Adenosine A(2A) receptor, BAY60-6583 (PubChem CID: 11717831), CCPA (PubChem CID: 123807), CGS21680 (PubChem CID: 3086599), Cl-IB-MECA (PubChem CID: 3035850), G protein-coupled receptors, Istradefylline (PubChem CID: 5311037), LUF5448 (PubChem CID: 69538223), Label-free, Lymphoblastoid cell lines, NECA (PubChem CID: 448222), Precision medicine, Single Nucleotide Polymorphism, ZM241385 (PubChem CID: 176407) | Biochemical pharmacology |
| Natriuretic peptides in the central nervous system: Novel targets for cognitive impairment. | Mahinrad S, de Craen AJM, Yasar S, van Heemst D, Sabayan B | 2016-09-01 | Central nervous system, Cognitive impairment, Natriuretic peptides | Neuroscience and biobehavioral reviews |
| High-sensitivity cardiac troponin T is associated with cognitive decline in older adults at high cardiovascular risk. | Wijsman LW, de Craen AJ, Trompet S, Sabayan B, Muller M, Stott DJ, Ford I, Welsh P, Westendorp RG, Jukema JW, Sattar N, Mooijaart SP | 2016-09-01 | Cardiac troponin T, N-terminal pro-brain natriuretic peptide, cardiovascular diseases, cognition | European journal of preventive cardiology |
| The development, implementation and evaluation of a transitional care programme to improve outcomes of frail older patients after hospitalisation. | Heim N, Rolden H, van Fenema EM, Weverling-Rijnsburger AW, Tuijl JP, Jue P, Oleksik AM, de Craen AJ, Mooijaart SP, Blauw GJ, Westendorp RG, van der Mast RC, van Everdinck IE | 2016-09-01 | integrated care, quality improvement, transitional care | Age and ageing |
| Employing biomarkers of healthy ageing for leveraging genetic studies into human longevity. | Deelen J, van den Akker EB, Trompet S, van Heemst D, Mooijaart SP, Slagboom PE, Beekman M | 2016-09-01 | Biomarkers, Genetics, Healthy ageing, Human longevity | Experimental gerontology |
| Latent class analysis of the Apathy Scale does not identify subtypes of apathy in general population-based older persons. | Groeneweg-Koolhoven I, Huitema LJ, de Waal MW, Stek ML, Gussekloo J, van der Mast RC, Rhebergen D | 2016-09-01 | Apathy Scale, apathy, apathy subtypes, latent class analysis, old age | International journal of geriatric psychiatry |
| Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARK-AGE Study. | Valentini E, Zampieri M, Malavolta M, Bacalini MG, Calabrese R, Guastafierro T, Reale A, Franceschi C, Hervonen A, Koller B, Bernhardt J, Slagboom PE, Toussaint O, Sikora E, Gonos ES, Breusing N, Grune T, Jansen E, Dollé ME, Moreno-Villanueva M, Sindlinger T, Bürkle A, Ciccarone F, Caiafa P | 2016-08-29 | DNA hydroxymethylation, TDG, aging, genesTET | Aging |
| Improving comfort in people with dementia and pneumonia: a cluster randomized trial. | van der Maaden T, de Vet HC, Achterberg WP, Boersma F, Schols JM, Mehr DR, Galindo-Garre F, Hertogh CM, Koopmans RT, van der Steen JT | 2016-08-11 | Dementia, Discomfort, Nursing homes, Pneumonia, Practice guideline, Trial | BMC medicine |
| Neo-cartilage engineered from primary chondrocytes is epigenetically similar to autologous cartilage, in contrast to using mesenchymal stem cells. | Bomer N, den Hollander W, Suchiman H, Houtman E, Slieker RC, Heijmans BT, Slagboom PE, Nelissen RG, Ramos YF, Meulenbelt I | 2016-08-01 | Articular cartilage, Chondrocytes, DNA methylation, Stem cells, Tissue engineering | Osteoarthritis and cartilage |
| Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study. | Ciccarone F, Malavolta M, Calabrese R, Guastafierro T, Bacalini MG, Reale A, Franceschi C, Capri M, Hervonen A, Hurme M, Grubeck-Loebenstein B, Koller B, Bernhardt J, Schӧn C, Slagboom PE, Toussaint O, Sikora E, Gonos ES, Breusing N, Grune T, Jansen E, Dollé M, Moreno-Villanueva M, Sindlinger T, Bürkle A, Zampieri M, Caiafa P | 2016-08-01 | DNA methylation, DNMT1, DNMT3B, aging | Aging cell |
| P16INK4a Positive Cells in Human Skin Are Indicative of Local Elastic Fiber Morphology, Facial Wrinkling, and Perceived Age. | Waaijer ME, Gunn DA, Adams PD, Pawlikowski JS, Griffiths CE, van Heemst D, Slagboom PE, Westendorp RG, Maier AB | 2016-08-01 | Cell senescence, Elastic fiber, Skin, Wrinkle, p16INK4a | The journals of gerontology. Series A, Biological sciences and medical sciences |
| Assessment of the contribution of APOE gene variants to metabolic phenotypes associated with familial longevity at middle age. | Noordam R, Oudt CH, Deelen J, Slagboom PE, Beekman M, van Heemst D | 2016-08-01 | 25-hydroxyvitamin D, APOE, glucose, human longevity, mediation | Aging |
| Early and extraordinary peaks in physical performance come with a longevity cost. | van de Vijver PL, van Bodegom D, Westendorp RG | 2016-08-01 | athletes, development, life history theory, longevity, personal record, trade-off | Aging |
| Prediction of 90-day mortality in older patients after discharge from an emergency department: a retrospective follow-up study. | Hofman SE, Lucke JA, Heim N, de Gelder J, Fogteloo AJ, Heringhaus C, de Groot B, de Craen AJ, Blauw GJ, Mooijaart SP | 2016-07-13 | Emergency medicine, Geriatrics, Mortality, Risk factors | BMC emergency medicine |
| Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels. | van Leeuwen EM, Sabo A, Bis JC, Huffman JE, Manichaikul A, Smith AV, Feitosa MF, Demissie S, Joshi PK, Duan Q, Marten J, van Klinken JB, Surakka I, Nolte IM, Zhang W, Mbarek H, Li-Gao R, Trompet S, Verweij N, Evangelou E, Lyytikäinen LP, Tayo BO, Deelen J, van der Most PJ, van der Laan SW, Arking DE, Morrison A, Dehghan A, Franco OH, Hofman A, Rivadeneira F, Sijbrands EJ, Uitterlinden AG, Mychaleckyj JC, Campbell A, Hocking LJ, Padmanabhan S, Brody JA, Rice KM, White CC, Harris T, Isaacs A, Campbell H, Lange LA, Rudan I, Kolcic I, Navarro P, Zemunik T, Salomaa V, Kooner AS, Kooner JS, Lehne B, Scott WR, Tan ST, de Geus EJ, Milaneschi Y, Penninx BW, Willemsen G, de Mutsert R, Ford I, Gansevoort RT, Segura-Lepe MP, Raitakari OT, Viikari JS, Nikus K, Forrester T, McKenzie CA, de Craen AJ, de Ruijter HM, Pasterkamp G, Snieder H, Oldehinkel AJ, Slagboom PE, Cooper RS, Kähönen M, Lehtimäki T, Elliott P, van der Harst P, Jukema JW, Mook-Kanamori DO, Boomsma DI, Chambers JC, Swertz M, Ripatti S, Willems van Dijk K, Vitart V, Polasek O, Hayward C, Wilson JG, Wilson JF, Gudnason V, Rich SS, Psaty BM, Borecki IB, Boerwinkle E, Rotter JI, Cupples LA, van Duijn CM | 2016-07-01 | Complex traits, Epidemiology, Genetics, Genome-wide, circulating lipid levels | Journal of medical genetics |
| Genetic variants determining survival and fertility in an adverse African environment: a population-based large-scale candidate gene association study. | Koopman JJ, Pijpe J, Böhringer S, van Bodegom D, Eriksson UK, Sanchez-Faddeev H, Ziem JB, Zwaan B, Slagboom PE, de Knijff P, Westendorp RG | 2016-07-01 | Africa, SNP, aging, evolution, fertility, gene, human, life history, survival | Aging |
| Regression Discontinuity Design: Simulation and Application in Two Cardiovascular Trials with Continuous Outcomes. | van Leeuwen N, Lingsma HF, de Craen AJ, Nieboer D, Mooijaart SP, Richard E, Steyerberg EW | 2016-07-01 | Epidemiology (Cambridge, Mass.) | |
| Risk stratification and treatment effect of statins in secondary cardiovascular prevention in old age: Additive value of N-terminal pro-B-type natriuretic peptide. | Poortvliet RK, van Peet PG, de Craen AJ, Mertens BJ, Mooijaart SP, Wijsman LW, Drewes YM, Ford I, Sattar N, Jukema JW, Stott DJ, de Ruijter W, Gussekloo J | 2016-07-01 | Aged, cardiovascular disease, hydroxymethylglutaryl-CoA reductase inhibitors, pro-brain natriuretic peptide, risk factors, secondary prevention | European journal of preventive cardiology |
| Blood lipids influence DNA methylation in circulating cells. | Dekkers KF, van Iterson M, Slieker RC, Moed MH, Bonder MJ, van Galen M, Mei H, Zhernakova DV, van den Berg LH, Deelen J, van Dongen J, van Heemst D, Hofman A, Hottenga JJ, van der Kallen CJ, Schalkwijk CG, Stehouwer CD, Tigchelaar EF, Uitterlinden AG, Willemsen G, Zhernakova A, Franke L, 't Hoen PA, Jansen R, van Meurs J, Boomsma DI, van Duijn CM, van Greevenbroek MM, Veldink JH, Wijmenga C, van Zwet EW, Slagboom PE, Jukema JW, Heijmans BT | 2016-06-27 | DNA methylation, Gene expression, Lipids, Mendelian randomization | Genome biology |
| Evaluation of the Use of Home Blood Pressure Measurement Using Mobile Phone-Assisted Technology: The iVitality Proof-of-Principle Study. | Wijsman LW, Richard E, Cachucho R, de Craen AJ, Jongstra S, Mooijaart SP | 2016-06-13 | dementia, home-based measurements, hypertension, mobile phone | JMIR mHealth and uHealth |
| The multifaceted interplay between lipids and epigenetics. | Dekkers KF, Slagboom PE, Jukema JW, Heijmans BT | 2016-06-01 | Current opinion in lipidology | |
| Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. | Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpeläinen TO, Lu Y, Mägi R, Mihailov E, Pers TH, Rüeger S, Teumer A, Ehret GB, Ferreira T, Heard-Costa NL, Karjalainen J, Lagou V, Mahajan A, Neinast MD, Prokopenko I, Simino J, Teslovich TM, Jansen R, Westra HJ, White CC, Absher D, Ahluwalia TS, Ahmad S, Albrecht E, Alves AC, Bragg-Gresham JL, de Craen AJ, Bis JC, Bonnefond A, Boucher G, Cadby G, Cheng YC, Chiang CW, Delgado G, Demirkan A, Dueker N, Eklund N, Eiriksdottir G, Eriksson J, Feenstra B, Fischer K, Frau F, Galesloot TE, Geller F, Goel A, Gorski M, Grammer TB, Gustafsson S, Haitjema S, Hottenga JJ, Huffman JE, Jackson AU, Jacobs KB, Johansson Å, Kaakinen M, Kleber ME, Lahti J, Mateo Leach I, Lehne B, Liu Y, Lo KS, Lorentzon M, Luan J, Madden PA, Mangino M, McKnight B, Medina-Gomez C, Monda KL, Montasser ME, Müller G, Müller-Nurasyid M, Nolte IM, Panoutsopoulou K, Pascoe L, Paternoster L, Rayner NW, Renström F, Rizzi F, Rose LM, Ryan KA, Salo P, Sanna S, Scharnagl H, Shi J, Smith AV, Southam L, Stančáková A, Steinthorsdottir V, Strawbridge RJ, Sung YJ, Tachmazidou I, Tanaka T, Thorleifsson G, Trompet S, Pervjakova N, Tyrer JP, Vandenput L, van der Laan SW, van der Velde N, van Setten J, van Vliet-Ostaptchouk JV, Verweij N, Vlachopoulou E, Waite LL, Wang SR, Wang Z, Wild SH, Willenborg C, Wilson JF, Wong A, Yang J, Yengo L, Yerges-Armstrong LM, Yu L, Zhang W, Zhao JH, Andersson EA, Bakker SJ, Baldassarre D, Banasik K, Barcella M, Barlassina C, Bellis C, Benaglio P, Blangero J, Blüher M, Bonnet F, Bonnycastle LL, Boyd HA, Bruinenberg M, Buchman AS, Campbell H, Chen YI, Chines PS, Claudi-Boehm S, Cole J, Collins FS, de Geus EJ, de Groot LC, Dimitriou M, Duan J, Enroth S, Eury E, Farmaki AE, Forouhi NG, Friedrich N, Gejman PV, Gigante B, Glorioso N, Go AS, Gottesman O, Gräßler J, Grallert H, Grarup N, Gu YM, Broer L, Ham AC, Hansen T, Harris TB, Hartman CA, Hassinen M, Hastie N, Hattersley AT, Heath AC, Henders AK, Hernandez D, Hillege H, Holmen O, Hovingh KG, Hui J, Husemoen LL, Hutri-Kähönen N, Hysi PG, Illig T, De Jager PL, Jalilzadeh S, Jørgensen T, Jukema JW, Juonala M, Kanoni S, Karaleftheri M, Khaw KT, Kinnunen L, Kittner SJ, Koenig W, Kolcic I, Kovacs P, Krarup NT, Kratzer W, Krüger J, Kuh D, Kumari M, Kyriakou T, Langenberg C, Lannfelt L, Lanzani C, Lotay V, Launer LJ, Leander K, Lindström J, Linneberg A, Liu YP, Lobbens S, Luben R, Lyssenko V, Männistö S, Magnusson PK, McArdle WL, Menni C, Merger S, Milani L, Montgomery GW, Morris AP, Narisu N, Nelis M, Ong KK, Palotie A, Pérusse L, Pichler I, Pilia MG, Pouta A, Rheinberger M, Ribel-Madsen R, Richards M, Rice KM, Rice TK, Rivolta C, Salomaa V, Sanders AR, Sarzynski MA, Scholtens S, Scott RA, Scott WR, Sebert S, Sengupta S, Sennblad B, Seufferlein T, Silveira A, Slagboom PE, Smit JH, Sparsø TH, Stirrups K, Stolk RP, Stringham HM, Swertz MA, Swift AJ, Syvänen AC, Tan ST, Thorand B, Tönjes A, Tremblay A, Tsafantakis E, van der Most PJ, Völker U, Vohl MC, Vonk JM, Waldenberger M, Walker RW, Wennauer R, Widén E, Willemsen G, Wilsgaard T, Wright AF, Zillikens MC, van Dijk SC, van Schoor NM, Asselbergs FW, de Bakker PI, Beckmann JS, Beilby J, Bennett DA, Bergman RN, Bergmann S, Böger CA, Boehm BO, Boerwinkle E, Boomsma DI, Bornstein SR, Bottinger EP, Bouchard C, Chambers JC, Chanock SJ, Chasman DI, Cucca F, Cusi D, Dedoussis G, Erdmann J, Eriksson JG, Evans DA, de Faire U, Farrall M, Ferrucci L, Ford I, Franke L, Franks PW, Froguel P, Gansevoort RT, Gieger C, Grönberg H, Gudnason V, Gyllensten U, Hall P, Hamsten A, van der Harst P, Hayward C, Heliövaara M, Hengstenberg C, Hicks AA, Hingorani A, Hofman A, Hu F, Huikuri HV, Hveem K, James AL, Jordan JM, Jula A, Kähönen M, Kajantie E, Kathiresan S, Kiemeney LA, Kivimaki M, Knekt PB, Koistinen HA, Kooner JS, Koskinen S, Kuusisto J, Maerz W, Martin NG, Laakso M, Lakka TA, Lehtimäki T, Lettre G, Levinson DF, Lind L, Lokki ML, Mäntyselkä P, Melbye M, Metspalu A, Mitchell BD, Moll FL, Murray JC, Musk AW, Nieminen MS, Njølstad I, Ohlsson C, Oldehinkel AJ, Oostra BA, Palmer LJ, Pankow JS, Pasterkamp G, Pedersen NL, Pedersen O, Penninx BW, Perola M, Peters A, Polašek O, Pramstaller PP, Psaty BM, Qi L, Quertermous T, Raitakari OT, Rankinen T, Rauramaa R, Ridker PM, Rioux JD, Rivadeneira F, Rotter JI, Rudan I, den Ruijter HM, Saltevo J, Sattar N, Schunkert H, Schwarz PE, Shuldiner AR, Sinisalo J, Snieder H, Sørensen TI, Spector TD, Staessen JA, Stefania B, Thorsteinsdottir U, Stumvoll M, Tardif JC, Tremoli E, Tuomilehto J, Uitterlinden AG, Uusitupa M, Verbeek AL, Vermeulen SH, Viikari JS, Vitart V, Völzke H, Vollenweider P, Waeber G, Walker M, Wallaschofski H, Wareham NJ, Watkins H, Zeggini E, Chakravarti A, Clegg DJ, Cupples LA, Gordon-Larsen P, Jaquish CE, Rao DC, Abecasis GR, Assimes TL, Barroso I, Berndt SI, Boehnke M, Deloukas P, Fox CS, Groop LC, Hunter DJ, Ingelsson E, Kaplan RC, McCarthy MI, Mohlke KL, O'Connell JR, Schlessinger D, Strachan DP, Stefansson K, van Duijn CM, Hirschhorn JN, Lindgren CM, Heid IM, North KE, Borecki IB, Kutalik Z, Loos RJ | 2016-06-01 | PLoS genetics | |
| Are elevated plasma amino acids causally linked to type 2 diabetes, or are they rather innocent bystanders? | Oudt CH, Noordam R, van Heemst D | 2016-06-01 | Nutrition, metabolism, and cardiovascular diseases : NMCD | |
| The uncertain future of lay counsellors: continuation of HIV services in Lesotho under pressure. | Bemelmans M, Goux D, Baert S, van Cutsem G, Motsamai M, Philips M, van Damme W, Mwale H, Biot M, van den Akker T | 2016-06-01 | ART, HIV/AIDS, Lesotho, community health worker, health policy, health system, human resources for health, lay counsellors | Health policy and planning |
| An Emerging Epidemic of Noncommunicable Diseases in Developing Populations Due to a Triple Evolutionary Mismatch. | Koopman JJ, van Bodegom D, Ziem JB, Westendorp RG | 2016-06-01 | The American journal of tropical medicine and hygiene | |
| Predicting mortality in acutely hospitalized older patients: a retrospective cohort study. | de Gelder J, Lucke JA, Heim N, de Craen AJ, Lourens SD, Steyerberg EW, de Groot B, Fogteloo AJ, Blauw GJ, Mooijaart SP | 2016-06-01 | Acute hospitalization, Elderly, Mortality, Older adults, Prediction | Internal and emergency medicine |
| The effect of pain on presence and severity of depressive disorders in older persons: The role of perceived control as mediator. | de Waal MW, Hegeman JM, Gussekloo J, Verhaak PF, van der Mast RC, Comijs HC | 2016-06-01 | Aged, Depressive disorder, Mediator, Pain, Perceived control | Journal of affective disorders |
| The MC1R Gene and Youthful Looks. | Liu F, Hamer MA, Deelen J, Lall JS, Jacobs L, van Heemst D, Murray PG, Wollstein A, de Craen AJ, Uh HW, Zeng C, Hofman A, Uitterlinden AG, Houwing-Duistermaat JJ, Pardo LM, Beekman M, Slagboom PE, Nijsten T, Kayser M, Gunn DA | 2016-05-09 | GWAS, MC1R, age, appearance, facial aging, perceived facial age, skin | Current biology : CB |
| Liver Fat Assessed With CT Relates to MRI Markers of Incipient Brain Injury in Middle-Aged to Elderly Overweight Persons. | Sala M, van der Grond J, de Mutsert R, van Heemst D, Slagboom PE, Kroft LJ, de Roos A | 2016-05-01 | body fat distribution, brain MRI, liver fat, obesity | AJR. American journal of roentgenology |
| Severe acute maternal morbidity in multiple pregnancies: a nationwide cohort study. | Witteveen T, Van Den Akker T, Zwart JJ, Bloemenkamp KW, Van Roosmalen J | 2016-05-01 | maternal health, maternal mortality, multiple pregnancy, obstetrics, quality of care, reproductive health, severe acute maternal morbidity | American journal of obstetrics and gynecology |
| Tobacco smoking is associated with DNA methylation of diabetes susceptibility genes. | Ligthart S, Steenaard RV, Peters MJ, van Meurs JB, Sijbrands EJ, Uitterlinden AG, Bonder MJ, Hofman A, Franco OH, Dehghan A | 2016-05-01 | DNA methylation, Gene expression, Tobacco smoking, Type 2 diabetes | Diabetologia |
| How do general practitioners identify inflammatory arthritis? A cohort analysis of Dutch general practitioner electronic medical records. | Newsum EC, de Waal MW, van Steenbergen HW, Gussekloo J, van der Helm-van Mil AH | 2016-05-01 | general practitioner, inflammatory arthritis, referral to secondary care, symptoms and signs | Rheumatology (Oxford, England) |
| An Internet-Based Physical Activity Intervention to Improve Quality of Life of Inactive Older Adults: A Randomized Controlled Trial. | Broekhuizen K, de Gelder J, Wijsman CA, Wijsman LW, Westendorp RG, Verhagen E, Slagboom PE, de Craen AJ, van Mechelen W, van Heemst D, van der Ouderaa F, Mooijaart SP | 2016-04-27 | Internet, physical activity, quality of life | Journal of medical Internet research |
| Genetic and environmental influences interact with age and sex in shaping the human methylome. | van Dongen J, Nivard MG, Willemsen G, Hottenga JJ, Helmer Q, Dolan CV, Ehli EA, Davies GE, van Iterson M, Breeze CE, Beck S, Suchiman HE, Jansen R, van Meurs JB, Heijmans BT, Slagboom PE, Boomsma DI | 2016-04-07 | Nature communications | |
| Non-response to (statin) therapy: the importance of distinguishing non-responders from non-adherers in pharmacogenetic studies. | Trompet S, Postmus I, Slagboom PE, Heijmans BT, Smit RA, Maier AB, Buckley BM, Sattar N, Stott DJ, Ford I, Westendorp RG, de Craen AJ, Jukema JW | 2016-04-01 | Adherence, Cardiovascular, Pharmacogenetics, Statins | European journal of clinical pharmacology |
| Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs. | Ricaño-Ponce I, Zhernakova DV, Deelen P, Luo O, Li X, Isaacs A, Karjalainen J, Di Tommaso J, Borek ZA, Zorro MM, Gutierrez-Achury J, Uitterlinden AG, Hofman A, van Meurs J, Netea MG, Jonkers IH, Withoff S, van Duijn CM, Li Y, Ruan Y, Franke L, Wijmenga C, Kumar V | 2016-04-01 | Causal genes, Genome-wide association, Long non-coding RNAs, RNA-sequencing, eQTLs | Journal of autoimmunity |
| Maternal mortality and severe morbidity in a migration perspective. | van den Akker T, van Roosmalen J | 2016-04-01 | maternal health services, maternal mortality, pregnancy complications, quality of health care, severe acute maternal morbidity, transients and migrants | Best practice & research. Clinical obstetrics & gynaecology |
| Continuous and caring support right now. | van Roosmalen J, van den Akker T | 2016-04-01 | BJOG : an international journal of obstetrics and gynaecology | |
| Calculating the Rate of Senescence From Mortality Data: An Analysis of Data From the ERA-EDTA Registry. | Koopman JJ, Rozing MP, Kramer A, Abad JM, Finne P, Heaf JG, Hoitsma AJ, De Meester JM, Palsson R, Postorino M, Ravani P, Wanner C, Jager KJ, van Bodegom D, Westendorp RG | 2016-04-01 | Acceleration of mortality, Aging, Gompertz model., Modeling, Senescence, Senescence rate | The journals of gerontology. Series A, Biological sciences and medical sciences |
| Transmission of human mtDNA heteroplasmy in the Genome of the Netherlands families: support for a variable-size bottleneck. | Li M, Rothwell R, Vermaat M, Wachsmuth M, Schröder R, Laros JF, van Oven M, de Bakker PI, Bovenberg JA, van Duijn CM, van Ommen GJ, Slagboom PE, Swertz MA, Wijmenga C, Kayser M, Boomsma DI, Zöllner S, de Knijff P, Stoneking M | 2016-04-01 | Genome research | |
| Older people coping with low mood: a qualitative study. | von Faber M, van der Geest G, van der Weele GM, Blom JW, van der Mast RC, Reis R, Gussekloo J | 2016-04-01 | coping, depressive symptoms, older adults, qualitative research, the Netherlands | International psychogeriatrics |
| Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA. | Kettunen J, Demirkan A, Würtz P, Draisma HH, Haller T, Rawal R, Vaarhorst A, Kangas AJ, Lyytikäinen LP, Pirinen M, Pool R, Sarin AP, Soininen P, Tukiainen T, Wang Q, Tiainen M, Tynkkynen T, Amin N, Zeller T, Beekman M, Deelen J, van Dijk KW, Esko T, Hottenga JJ, van Leeuwen EM, Lehtimäki T, Mihailov E, Rose RJ, de Craen AJ, Gieger C, Kähönen M, Perola M, Blankenberg S, Savolainen MJ, Verhoeven A, Viikari J, Willemsen G, Boomsma DI, van Duijn CM, Eriksson J, Jula A, Järvelin MR, Kaprio J, Metspalu A, Raitakari O, Salomaa V, Slagboom PE, Waldenberger M, Ripatti S, Ala-Korpela M | 2016-03-23 | Nature communications | |
| 10-Second heart rate variability and cognitive function in old age. | Mahinrad S, Jukema JW, van Heemst D, Macfarlane PW, Clark EN, de Craen AJ, Sabayan B | 2016-03-22 | Neurology | |
| Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2. | van den Akker EB, Pitts SJ, Deelen J, Moed MH, Potluri S, van Rooij J, Suchiman HE, Lakenberg N, de Dijcker WJ, Uitterlinden AG, Kraaij R, Hofman A, de Craen AJ, Houwing-Duistermaat JJ, van Ommen GJ, Cox DR, van Meurs JB, Beekman M, Reinders MJ, Slagboom PE | 2016-03-17 | Blood | |
| The effect of forced exercise on knee joints in Dio2(-/-) mice: type II iodothyronine deiodinase-deficient mice are less prone to develop OA-like cartilage damage upon excessive mechanical stress. | Bomer N, Cornelis FM, Ramos YF, den Hollander W, Storms L, van der Breggen R, Lakenberg N, Slagboom PE, Meulenbelt I, Lories RJ | 2016-03-01 | Disease Activity, Knee Osteoarthritis, Osteoarthritis, Treatment | Annals of the rheumatic diseases |
| Effect of calendar age on physical performance: A comparison of standard clinical measures with instrumented measures in middle-aged to older adults. | Stijntjes M, Meskers CG, de Craen AJ, van Lummel RC, Rispens SM, Slagboom PE, Maier AB | 2016-03-01 | Aging, Body fixed sensor, Calendar age, Familial longevity, Physical performance | Gait & posture |
| Disentangling rectangularization and life span extension with the moving rectangle method. | Schalkwijk FH, Koopman JJ, Ghariq E, de Beer JA, van Bodegom D, Westendorp RG | 2016-03-01 | Aging, Life expectancy, Life span, Longevity, Moving rectangle method, Rectangularization | Annals of epidemiology |
| Measuring aging rates of mice subjected to caloric restriction and genetic disruption of growth hormone signaling. | Koopman JJ, van Heemst D, van Bodegom D, Bonkowski MS, Sun LY, Bartke A | 2016-03-01 | Gompertz model, aging, aging rate, caloric restriction, growth hormone, mice | Aging |
| Blood Pressure Lowering Medication, Visit-to-Visit Blood Pressure Variability, and Cognitive Function in Old Age. | Wijsman LW, de Craen AJ, Muller M, Sabayan B, Stott D, Ford I, Trompet S, Jukema JW, Westendorp RG, Mooijaart SP | 2016-03-01 | blood pressure, cognition, hypertension, medication, variability. | American journal of hypertension |
| Physician’s Prescribing Preference as an Instrumental Variable: Exploring Assumptions Using Survey Data. | Boef AG, le Cessie S, Dekkers OM, Frey P, Kearney PM, Kerse N, Mallen CD, McCarthy VJ, Mooijaart SP, Muth C, Rodondi N, Rosemann T, Russell A, Schers H, Virgini V, de Waal MW, Warner A, Gussekloo J, den Elzen WP | 2016-03-01 | Epidemiology (Cambridge, Mass.) | |
| Detecting dispersed duplications in high-throughput sequencing data using a database-free approach. | Kroon M, Lameijer EW, Lakenberg N, Hehir-Kwa JY, Thung DT, Slagboom PE, Kok JN, Ye K | 2016-02-15 | Bioinformatics (Oxford, England) | |
| GWAS for executive function and processing speed suggests involvement of the CADM2 gene. | Ibrahim-Verbaas CA, Bressler J, Debette S, Schuur M, Smith AV, Bis JC, Davies G, Trompet S, Smith JA, Wolf C, Chibnik LB, Liu Y, Vitart V, Kirin M, Petrovic K, Polasek O, Zgaga L, Fawns-Ritchie C, Hoffmann P, Karjalainen J, Lahti J, Llewellyn DJ, Schmidt CO, Mather KA, Chouraki V, Sun Q, Resnick SM, Rose LM, Oldmeadow C, Stewart M, Smith BH, Gudnason V, Yang Q, Mirza SS, Jukema JW, deJager PL, Harris TB, Liewald DC, Amin N, Coker LH, Stegle O, Lopez OL, Schmidt R, Teumer A, Ford I, Karbalai N, Becker JT, Jonsdottir MK, Au R, Fehrmann R, Herms S, Nalls M, Zhao W, Turner ST, Yaffe K, Lohman K, van Swieten JC, Kardia S, Knopman DS, Meeks WM, Heiss G, Holliday EG, Schofield PW, Tanaka T, Stott DJ, Wang J, Ridker P, Gow AJ, Pattie A, Starr JM, Hocking LJ, Armstrong NJ, McLachlan S, Shulman JM, Pilling LC, Eiriksdottir G, Scott RJ, Kochan NA, Palotie A, Hsieh YC, Eriksson JG, Penman A, Gottesman RF, Oostra BA, Yu L, DeStefano AL, Beiser A, Garcia M, Rotter JI, Nöthen MM, Hofman A, Slagboom PE, Westendorp R, Buckley BM, Wolf PA, Uitterlinden AG, Psaty BM, Grabe HJ, Bandinelli S, Chasman DI, Grodstein F, Räikkönen K, Lambert JC, Porteous DJ, Price JF, Sachdev PS, Ferrucci L, Attia JR, Rudan I, Hayward C, Wright AF, Wilson JF, Cichon S, Franke L, Schmidt H, Ding J, de Craen A, Fornage M, Bennett DA, Deary IJ, Ikram MA, Launer LJ, Fitzpatrick AL, Seshadri S, van Duijn CM, Mosley TH | 2016-02-01 | Molecular psychiatry | |
| Copy number variation associates with mortality in long-lived individuals: a genome-wide assessment. | Nygaard M, Debrabant B, Tan Q, Deelen J, Andersen-Ranberg K, de Craen AJ, Beekman M, Jeune B, Slagboom PE, Christensen K, Christiansen L | 2016-02-01 | aging, copy number variation, deletions, genetics, long-lived individuals, mortality | Aging cell |
| Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. | Kilpeläinen TO, Carli JF, Skowronski AA, Sun Q, Kriebel J, Feitosa MF, Hedman ÅK, Drong AW, Hayes JE, Zhao J, Pers TH, Schick U, Grarup N, Kutalik Z, Trompet S, Mangino M, Kristiansson K, Beekman M, Lyytikäinen LP, Eriksson J, Henneman P, Lahti J, Tanaka T, Luan J, Del Greco M F, Pasko D, Renström F, Willems SM, Mahajan A, Rose LM, Guo X, Liu Y, Kleber ME, Pérusse L, Gaunt T, Ahluwalia TS, Ju Sung Y, Ramos YF, Amin N, Amuzu A, Barroso I, Bellis C, Blangero J, Buckley BM, Böhringer S, I Chen YD, de Craen AJ, Crosslin DR, Dale CE, Dastani Z, Day FR, Deelen J, Delgado GE, Demirkan A, Finucane FM, Ford I, Garcia ME, Gieger C, Gustafsson S, Hallmans G, Hankinson SE, Havulinna AS, Herder C, Hernandez D, Hicks AA, Hunter DJ, Illig T, Ingelsson E, Ioan-Facsinay A, Jansson JO, Jenny NS, Jørgensen ME, Jørgensen T, Karlsson M, Koenig W, Kraft P, Kwekkeboom J, Laatikainen T, Ladwig KH, LeDuc CA, Lowe G, Lu Y, Marques-Vidal P, Meisinger C, Menni C, Morris AP, Myers RH, Männistö S, Nalls MA, Paternoster L, Peters A, Pradhan AD, Rankinen T, Rasmussen-Torvik LJ, Rathmann W, Rice TK, Brent Richards J, Ridker PM, Sattar N, Savage DB, Söderberg S, Timpson NJ, Vandenput L, van Heemst D, Uh HW, Vohl MC, Walker M, Wichmann HE, Widén E, Wood AR, Yao J, Zeller T, Zhang Y, Meulenbelt I, Kloppenburg M, Astrup A, Sørensen TI, Sarzynski MA, Rao DC, Jousilahti P, Vartiainen E, Hofman A, Rivadeneira F, Uitterlinden AG, Kajantie E, Osmond C, Palotie A, Eriksson JG, Heliövaara M, Knekt PB, Koskinen S, Jula A, Perola M, Huupponen RK, Viikari JS, Kähönen M, Lehtimäki T, Raitakari OT, Mellström D, Lorentzon M, Casas JP, Bandinelli S, März W, Isaacs A, van Dijk KW, van Duijn CM, Harris TB, Bouchard C, Allison MA, Chasman DI, Ohlsson C, Lind L, Scott RA, Langenberg C, Wareham NJ, Ferrucci L, Frayling TM, Pramstaller PP, Borecki IB, Waterworth DM, Bergmann S, Waeber G, Vollenweider P, Vestergaard H, Hansen T, Pedersen O, Hu FB, Eline Slagboom P, Grallert H, Spector TD, Jukema JW, Klein RJ, Schadt EE, Franks PW, Lindgren CM, Leibel RL, Loos RJ | 2016-02-01 | Nature communications | |
| Effects of a Stepwise Multidisciplinary Intervention for Challenging Behavior in Advanced Dementia: A Cluster Randomized Controlled Trial. | Pieper MJ, Francke AL, van der Steen JT, Scherder EJ, Twisk JW, Kovach CR, Achterberg WP | 2016-02-01 | challenging behavior, dementia, nursing home, psychotropic drug use, stepwise approach | Journal of the American Geriatrics Society |
| A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration. | de Vries PS, Chasman DI, Sabater-Lleal M, Chen MH, Huffman JE, Steri M, Tang W, Teumer A, Marioni RE, Grossmann V, Hottenga JJ, Trompet S, Müller-Nurasyid M, Zhao JH, Brody JA, Kleber ME, Guo X, Wang JJ, Auer PL, Attia JR, Yanek LR, Ahluwalia TS, Lahti J, Venturini C, Tanaka T, Bielak LF, Joshi PK, Rocanin-Arjo A, Kolcic I, Navarro P, Rose LM, Oldmeadow C, Riess H, Mazur J, Basu S, Goel A, Yang Q, Ghanbari M, Willemsen G, Rumley A, Fiorillo E, de Craen AJ, Grotevendt A, Scott R, Taylor KD, Delgado GE, Yao J, Kifley A, Kooperberg C, Qayyum R, Lopez LM, Berentzen TL, Räikkönen K, Mangino M, Bandinelli S, Peyser PA, Wild S, Trégouët DA, Wright AF, Marten J, Zemunik T, Morrison AC, Sennblad B, Tofler G, de Maat MP, de Geus EJ, Lowe GD, Zoledziewska M, Sattar N, Binder H, Völker U, Waldenberger M, Khaw KT, Mcknight B, Huang J, Jenny NS, Holliday EG, Qi L, Mcevoy MG, Becker DM, Starr JM, Sarin AP, Hysi PG, Hernandez DG, Jhun MA, Campbell H, Hamsten A, Rivadeneira F, Mcardle WL, Slagboom PE, Zeller T, Koenig W, Psaty BM, Haritunians T, Liu J, Palotie A, Uitterlinden AG, Stott DJ, Hofman A, Franco OH, Polasek O, Rudan I, Morange PE, Wilson JF, Kardia SL, Ferrucci L, Spector TD, Eriksson JG, Hansen T, Deary IJ, Becker LC, Scott RJ, Mitchell P, März W, Wareham NJ, Peters A, Greinacher A, Wild PS, Jukema JW, Boomsma DI, Hayward C, Cucca F, Tracy R, Watkins H, Reiner AP, Folsom AR, Ridker PM, O'Donnell CJ, Smith NL, Strachan DP, Dehghan A | 2016-01-15 | Human molecular genetics | |
| Systematic discovery of complex insertions and deletions in human cancers. | Ye K, Wang J, Jayasinghe R, Lameijer EW, McMichael JF, Ning J, McLellan MD, Xie M, Cao S, Yellapantula V, Huang KL, Scott A, Foltz S, Niu B, Johnson KJ, Moed M, Slagboom PE, Chen F, Wendl MC, Ding L | 2016-01-01 | Nature medicine | |
| DNA damage markers in dermal fibroblasts in vitro reflect chronological donor age. | Waaijer ME, Croco E, Westendorp RG, Slagboom PE, Sedivy JM, Lorenzini A, Maier AB | 2016-01-01 | 53BP1, biological age, human aging, micronuclei, telomere-associated foci | Aging |
| Cerebral Microbleeds and Lacunar Infarcts Are Associated with Walking Speed Independent of Cognitive Performance in Middle-Aged to Older Adults. | Stijntjes M, de Craen AJ, van der Grond J, Meskers CG, Slagboom PE, Maier AB | 2016-01-01 | Gerontology | |
| Associations between joint effusion in the knee and gene expression levels in the circulation: a meta-analysis. | Peters MJ, Ramos YF, den Hollander W, Schiphof D, Hofman A, Uitterlinden AG, Oei EH, Slagboom PE, Kloppenburg M, Bloem JL, Bierma-Zeinstra SM, Meulenbelt I, van Meurs JB | 2016-01-01 | blood, inflammation, joint effusion, knee osteoarthritis, molecular markers | F1000Research |
| Aberrant Calreticulin Expression in Articular Cartilage of Dio2 Deficient Mice. | Bomer N, Cornelis FM, Ramos YF, den Hollander W, Lakenberg N, van der Breggen R, Storms L, Slagboom PE, Lories RJ, Meulenbelt I | 2016-01-01 | PloS one | |
| Physiological responding to stress in middle-aged males enriched for longevity: a social stress study. | Jansen SW, van Heemst D, van der Grond J, Westendorp R, Oei NY | 2016-01-01 | Area under the curve, TSST, blood pressure, cortisol, healthy ageing, heart rate | Stress (Amsterdam, Netherlands) |
| Comparative Analysis of the Equivital EQ02 Lifemonitor with Holter Ambulatory ECG Device for Continuous Measurement of ECG, Heart Rate, and Heart Rate Variability: A Validation Study for Precision and Accuracy. | Akintola AA, van de Pol V, Bimmel D, Maan AC, van Heemst D | 2016-01-01 | ECG, ECG artifact processing, Equivital-EQ02, Holter electrocardiogram, heart rate, heart rate variability (HRV), remote monitoring, validation study | Frontiers in physiology |
| Classification for Longevity Potential: The Use of Novel Biomarkers. | Beekman M, Uh HW, van Heemst D, Wuhrer M, Ruhaak LR, Gonzalez-Covarrubias V, Hankemeier T, Houwing-Duistermaat JJ, Slagboom PE | 2016-01-01 | Framingham Risk Score, biomarker, classification and prediction, human longevity potential, sex-specific analysis | Frontiers in public health |
| Familial Longevity Is Not Associated with Major Differences in the Hypothalamic-Pituitary-Gonadal Axis in Healthy Middle-Aged Men. | van der Spoel E, Roelfsema F, Jansen SW, Akintola AA, Ballieux BE, Cobbaert CM, Blauw GJ, Slagboom PE, Westendorp RG, Pijl H, van Heemst D | 2016-01-01 | approximate entropy, familial longevity, hormone secretion, hypothalamic–pituitary–gonadal axis, luteinizing hormone, temporal correlation, testosterone | Frontiers in endocrinology |
| Validating the WHO Maternal Near Miss Tool in a high-income country. | Witteveen T, de Koning I, Bezstarosti H, van den Akker T, van Roosmalen J, Bloemenkamp KW | 2016-01-01 | Maternal Near Miss Tool, Severe acute maternal morbidity, World Health Organization, high income country, maternal health, organ dysfunction | Acta obstetricia et gynecologica Scandinavica |
| Sustaining the future of HIV counselling to reach 90-90-90: a regional country analysis. | Bemelmans M, Baert S, Negussie E, Bygrave H, Biot M, Jamet C, Ellman T, Banda A, van den Akker T, Ford N | 2016-01-01 | HIV testing and counselling, HIV/AIDS, adherence support, antiretroviral therapy, community health workers, human resources for health, lay counsellors, lay workers, patient education and counselling, retention in care, sub-Saharan Africa, task shifting | Journal of the International AIDS Society |
| Metabolic effects of a 13-weeks lifestyle intervention in older adults: The Growing Old Together Study. | van de Rest O, Schutte BA, Deelen J, Stassen SA, van den Akker EB, van Heemst D, Dibbets-Schneider P, van Dipten-van der Veen RA, Kelderman M, Hankemeier T, Mooijaart SP, van der Grond J, Houwing-Duistermaat JJ, Beekman M, Feskens EJ, Slagboom PE | 2016-01-01 | caloric restriction, healthy ageing, lifestyle intervention, metabolic health, older adults, physical activity | Aging |
| Association between the rs7903146 Polymorphism in the TCF7L2 Gene and Parameters Derived with Continuous Glucose Monitoring in Individuals without Diabetes. | van der Kroef S, Noordam R, Deelen J, Akintola AA, Jansen SW, Postmus I, Wijsman CA, Beekman M, Mooijaart SP, Slagboom PE, van Heemst D | 2016-01-01 | PloS one | |
| Subclinical Thyroid Dysfunction and Depressive Symptoms among the Elderly: A Prospective Cohort Study. | Blum MR, Wijsman LW, Virgini VS, Bauer DC, den Elzen WP, Jukema JW, Buckley BM, de Craen AJ, Kearney PM, Stott DJ, Gussekloo J, Westendorp RG, Mooijaart SP, Rodondi N | 2016-01-01 | Neuroendocrinology | |
| Effectiveness and cost-effectiveness of a proactive, goal-oriented, integrated care model in general practice for older people. A cluster randomised controlled trial: Integrated Systematic Care for older People–the ISCOPE study. | Blom J, den Elzen W, van Houwelingen AH, Heijmans M, Stijnen T, Van den Hout W, Gussekloo J | 2016-01-01 | aged, integrated care, older people, primary care, proactive care | Age and ageing |
| Problems experienced by informal caregivers with older care recipients with and without cognitive impairment. | Van Bruggen S, Gussekloo J, Bode C, Touwen DP, Engberts DP, Blom JW | 2016-01-01 | Care issues of persons with dementia, cognition, community and home care; family geriatrics | Home health care services quarterly |
| Associations of Various Health-Ratings with Geriatric Giants, Mortality and Life Satisfaction in Older People. | Puvill T, Lindenberg J, Gussekloo J, de Craen AJ, Slaets JP, Westendorp RG | 2016-01-01 | PloS one | |
| Satisfaction in Older Persons and General Practitioners during the Implementation of Integrated Care. | Poot AJ, Caljouw MA, Waard CS, Wind AW, Gussekloo J | 2016-01-01 | PloS one | |
| Statin Use and Self-Reported Hindering Muscle Complaints in Older Persons: A Population Based Study. | van der Ploeg MA, Poortvliet RK, van Blijswijk SC, den Elzen WP, van Peet PG, de Ruijter W, Blom JW, Gussekloo J | 2016-01-01 | PloS one | |
| Robustness of Automated Methods for Brain Volume Measurements across Different MRI Field Strengths. | Heinen R, Bouvy WH, Mendrik AM, Viergever MA, Biessels GJ, de Bresser J | 2016-01-01 | PloS one | |
| Discharge home after acute stroke: Differences between older and younger patients. | Dutrieux RD, van Eijk M, van Mierlo ML, van Heugten CM, Visser-Meily JM, Achterberg WP | 2016-01-01 | Journal of rehabilitation medicine | |
| Orofacial Pain during Mastication in People with Dementia: Reliability Testing of the Orofacial Pain Scale for Non-Verbal Individuals. | de Vries MW, Visscher C, Delwel S, van der Steen JT, Pieper MJ, Scherder EJ, Achterberg WP, Lobbezoo F | 2016-01-01 | Behavioural neurology | |
| The Interactive Relationship between Pain, Psychosis, and Agitation in People with Dementia: Results from a Cluster-Randomised Clinical Trial. | Habiger TF, Flo E, Achterberg WP, Husebo BS | 2016-01-01 | Behavioural neurology | |
| [Effects of a stepwise approach to behavioural problems in dementia: a cluster randomised controlled trial]. | Pieper MJ, Francke AL, van der Steen JT, Scherder EJ, Twisk JW, Kovach CR, Achterberg WP | 2016-01-01 | Nederlands tijdschrift voor geneeskunde | |
| Characteristics Associated with Quality of Life in Long-Term Care Residents with Dementia: A Cross-Sectional Study. | Klapwijk MS, Caljouw MA, Pieper MJ, van der Steen JT, Achterberg WP | 2016-01-01 | Dementia and geriatric cognitive disorders | |
| Exploring the variation in implementation of a COPD disease management programme and its impact on health outcomes: a post hoc analysis of the RECODE cluster randomised trial. | Boland MR, Kruis AL, Huygens SA, Tsiachristas A, Assendelft WJ, Gussekloo J, Blom CM, Chavannes NH, Rutten-van Mölken MP | 2015-12-17 | NPJ primary care respiratory medicine | |
| Whole-cell biosensor for label-free detection of GPCR-mediated drug responses in personal cell lines. | Hillger JM, Schoop J, Boomsma DI, Slagboom PE, IJzerman AP, Heitman LH | 2015-12-15 | Cannabinoid receptor 2, CB2, G protein-coupled receptors, GPCR, Label-free, Lymphoblastoid cell lines, LCL, Personalized medicine, Precision medicine | Biosensors & bioelectronics |
| Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk. | Walsh KM, Codd V, Rice T, Nelson CP, Smirnov IV, McCoy LS, Hansen HM, Elhauge E, Ojha J, Francis SS, Madsen NR, Bracci PM, Pico AR, Molinaro AM, Tihan T, Berger MS, Chang SM, Prados MD, Jenkins RB, Wiemels JL, Samani NJ, Wiencke JK, Wrensch MR | 2015-12-15 | CST complex, glioma, single nucleotide polymorphism, telomerase, telomere | Oncotarget |
| Longitudinal follow-up study on fear of falling during and after rehabilitation in skilled nursing facilities. | Visschedijk JH, Caljouw MA, Bakkers E, van Balen R, Achterberg WP | 2015-12-04 | BMC geriatrics | |
| Markers of health and disease and pigmented spots in a middle-aged population. | van Drielen K, Gunn DA, Griffiths CE, Griffiths TW, Ogden S, Noordam R, Slagboom PE, van Heemst D, de Craen AJ | 2015-12-01 | The British journal of dermatology | |
| CD226 (DNAM-1) is associated with susceptibility to juvenile idiopathic arthritis. | Reinards TH, Albers HM, Brinkman DM, Kamphuis SS, van Rossum MA, Girschick HJ, Wouters C, Hoppenreijs EP, Saurenmann RK, Hinks A, Ellis JA, Bakker E, Verduijn W, Slagboom P, Huizinga TW, Toes RE, Houwing-Duistermaat JJ, ten Cate R, Schilham MW | 2015-12-01 | Autoimmune Diseases, Gene Polymorphism, Juvenile Idiopathic Arthritis, T Cells | Annals of the rheumatic diseases |
| CYP2D6 Metabolism in Frail Elderly Compared to Non-Frail Elderly: A Pilot Feasibility Study. | Opdam FL, Modak AS, Mooijaart SP, Louwerens M, de Waal MW, Gelderblom H, Guchelaar HJ | 2015-12-01 | Drugs & aging | |
| Global surgery and the dilemma for obstetricians. | Rijken MJ, Meguid T, van den Akker T, van Roosmalen J, Stekelenburg J | 2015-11-14 | Lancet (London, England) | |
| MARK-AGE biomarkers of ageing. | Bürkle A, Moreno-Villanueva M, Bernhard J, Blasco M, Zondag G, Hoeijmakers JH, Toussaint O, Grubeck-Loebenstein B, Mocchegiani E, Collino S, Gonos ES, Sikora E, Gradinaru D, Dollé M, Salmon M, Kristensen P, Griffiths HR, Libert C, Grune T, Breusing N, Simm A, Franceschi C, Capri M, Talbot D, Caiafa P, Friguet B, Slagboom PE, Hervonen A, Hurme M, Aspinall R | 2015-11-01 | Ageing biomarkers, Human studies, MARK-AGE | Mechanisms of ageing and development |
| White Matter Lesion Progression: Genome-Wide Search for Genetic Influences. | Hofer E, Cavalieri M, Bis JC, DeCarli C, Fornage M, Sigurdsson S, Srikanth V, Trompet S, Verhaaren BF, Wolf C, Yang Q, Adams HH, Amouyel P, Beiser A, Buckley BM, Callisaya M, Chauhan G, de Craen AJ, Dufouil C, van Duijn CM, Ford I, Freudenberger P, Gottesman RF, Gudnason V, Heiss G, Hofman A, Lumley T, Martinez O, Mazoyer B, Moran C, Niessen WJ, Phan T, Psaty BM, Satizabal CL, Sattar N, Schilling S, Shibata DK, Slagboom PE, Smith A, Stott DJ, Taylor KD, Thomson R, Töglhofer AM, Tzourio C, van Buchem M, Wang J, Westendorp RG, Windham BG, Vernooij MW, Zijdenbos A, Beare R, Debette S, Ikram MA, Jukema JW, Launer LJ, Longstreth WT, Mosley TH, Seshadri S, Schmidt H, Schmidt R | 2015-11-01 | aging, biological factors, cerebral small vessel diseases, magnetic resonance imaging, white matter lesions | Stroke |
| Association analysis of insulin-like growth factor-1 axis parameters with survival and functional status in nonagenarians of the Leiden Longevity Study. | van der Spoel E, Rozing MP, Houwing-Duistermaat JJ, Slagboom PE, Beekman M, de Craen AJ, Westendorp RG, van Heemst D | 2015-11-01 | IGF-1 axis, familial longevity, functional status, human, survival | Aging |
| GPs’ perspectives on secondary cardiovascular prevention in older age: a focus group study in the Netherlands. | van Peet PG, Drewes YM, Gussekloo J, de Ruijter W | 2015-11-01 | cardiovascular, general practice, guidelines as topic, older age, secondary prevention | The British journal of general practice : the journal of the Royal College of General Practitioners |
| Cost-effectiveness of integrated COPD care: the RECODE cluster randomised trial. | Boland MR, Kruis AL, Tsiachristas A, Assendelft WJ, Gussekloo J, Blom CM, Chavannes NH, Rutten-van Mölken MP | 2015-11-01 | HEALTH ECONOMICS, PRIMARY CARE, RESPIRATORY MEDICINE (see Thoracic Medicine) | BMJ open |
| The transcriptional landscape of age in human peripheral blood. | Peters MJ, Joehanes R, Pilling LC, Schurmann C, Conneely KN, Powell J, Reinmaa E, Sutphin GL, Zhernakova A, Schramm K, Wilson YA, Kobes S, Tukiainen T, Ramos YF, Göring HH, Fornage M, Liu Y, Gharib SA, Stranger BE, De Jager PL, Aviv A, Levy D, Murabito JM, Munson PJ, Huan T, Hofman A, Uitterlinden AG, Rivadeneira F, van Rooij J, Stolk L, Broer L, Verbiest MM, Jhamai M, Arp P, Metspalu A, Tserel L, Milani L, Samani NJ, Peterson P, Kasela S, Codd V, Peters A, Ward-Caviness CK, Herder C, Waldenberger M, Roden M, Singmann P, Zeilinger S, Illig T, Homuth G, Grabe HJ, Völzke H, Steil L, Kocher T, Murray A, Melzer D, Yaghootkar H, Bandinelli S, Moses EK, Kent JW, Curran JE, Johnson MP, Williams-Blangero S, Westra HJ, McRae AF, Smith JA, Kardia SL, Hovatta I, Perola M, Ripatti S, Salomaa V, Henders AK, Martin NG, Smith AK, Mehta D, Binder EB, Nylocks KM, Kennedy EM, Klengel T, Ding J, Suchy-Dicey AM, Enquobahrie DA, Brody J, Rotter JI, Chen YD, Houwing-Duistermaat J, Kloppenburg M, Slagboom PE, Helmer Q, den Hollander W, Bean S, Raj T, Bakhshi N, Wang QP, Oyston LJ, Psaty BM, Tracy RP, Montgomery GW, Turner ST, Blangero J, Meulenbelt I, Ressler KJ, Yang J, Franke L, Kettunen J, Visscher PM, Neely GG, Korstanje R, Hanson RL, Prokisch H, Ferrucci L, Esko T, Teumer A, van Meurs JB, Johnson AD | 2015-10-22 | Nature communications | |
| Resting heart rate, heart rate variability and functional decline in old age. | Ogliari G, Mahinrad S, Stott DJ, Jukema JW, Mooijaart SP, Macfarlane PW, Clark EN, Kearney PM, Westendorp RGJ, de Craen AJM, Sabayan B | 2015-10-20 | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne | |
| The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. | Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpeläinen TO, Lu Y, Mägi R, Mihailov E, Pers TH, Rüeger S, Teumer A, Ehret GB, Ferreira T, Heard-Costa NL, Karjalainen J, Lagou V, Mahajan A, Neinast MD, Prokopenko I, Simino J, Teslovich TM, Jansen R, Westra HJ, White CC, Absher D, Ahluwalia TS, Ahmad S, Albrecht E, Alves AC, Bragg-Gresham JL, de Craen AJ, Bis JC, Bonnefond A, Boucher G, Cadby G, Cheng YC, Chiang CW, Delgado G, Demirkan A, Dueker N, Eklund N, Eiriksdottir G, Eriksson J, Feenstra B, Fischer K, Frau F, Galesloot TE, Geller F, Goel A, Gorski M, Grammer TB, Gustafsson S, Haitjema S, Hottenga JJ, Huffman JE, Jackson AU, Jacobs KB, Johansson Å, Kaakinen M, Kleber ME, Lahti J, Mateo Leach I, Lehne B, Liu Y, Lo KS, Lorentzon M, Luan J, Madden PA, Mangino M, McKnight B, Medina-Gomez C, Monda KL, Montasser ME, Müller G, Müller-Nurasyid M, Nolte IM, Panoutsopoulou K, Pascoe L, Paternoster L, Rayner NW, Renström F, Rizzi F, Rose LM, Ryan KA, Salo P, Sanna S, Scharnagl H, Shi J, Smith AV, Southam L, Stančáková A, Steinthorsdottir V, Strawbridge RJ, Sung YJ, Tachmazidou I, Tanaka T, Thorleifsson G, Trompet S, Pervjakova N, Tyrer JP, Vandenput L, van der Laan SW, van der Velde N, van Setten J, van Vliet-Ostaptchouk JV, Verweij N, Vlachopoulou E, Waite LL, Wang SR, Wang Z, Wild SH, Willenborg C, Wilson JF, Wong A, Yang J, Yengo L, Yerges-Armstrong LM, Yu L, Zhang W, Zhao JH, Andersson EA, Bakker SJ, Baldassarre D, Banasik K, Barcella M, Barlassina C, Bellis C, Benaglio P, Blangero J, Blüher M, Bonnet F, Bonnycastle LL, Boyd HA, Bruinenberg M, Buchman AS, Campbell H, Chen YD, Chines PS, Claudi-Boehm S, Cole J, Collins FS, de Geus EJ, de Groot LC, Dimitriou M, Duan J, Enroth S, Eury E, Farmaki AE, Forouhi NG, Friedrich N, Gejman PV, Gigante B, Glorioso N, Go AS, Gottesman O, Gräßler J, Grallert H, Grarup N, Gu YM, Broer L, Ham AC, Hansen T, Harris TB, Hartman CA, Hassinen M, Hastie N, Hattersley AT, Heath AC, Henders AK, Hernandez D, Hillege H, Holmen O, Hovingh KG, Hui J, Husemoen LL, Hutri-Kähönen N, Hysi PG, Illig T, De Jager PL, Jalilzadeh S, Jørgensen T, Jukema JW, Juonala M, Kanoni S, Karaleftheri M, Khaw KT, Kinnunen L, Kittner SJ, Koenig W, Kolcic I, Kovacs P, Krarup NT, Kratzer W, Krüger J, Kuh D, Kumari M, Kyriakou T, Langenberg C, Lannfelt L, Lanzani C, Lotay V, Launer LJ, Leander K, Lindström J, Linneberg A, Liu YP, Lobbens S, Luben R, Lyssenko V, Männistö S, Magnusson PK, McArdle WL, Menni C, Merger S, Milani L, Montgomery GW, Morris AP, Narisu N, Nelis M, Ong KK, Palotie A, Pérusse L, Pichler I, Pilia MG, Pouta A, Rheinberger M, Ribel-Madsen R, Richards M, Rice KM, Rice TK, Rivolta C, Salomaa V, Sanders AR, Sarzynski MA, Scholtens S, Scott RA, Scott WR, Sebert S, Sengupta S, Sennblad B, Seufferlein T, Silveira A, Slagboom PE, Smit JH, Sparsø TH, Stirrups K, Stolk RP, Stringham HM, Swertz MA, Swift AJ, Syvänen AC, Tan ST, Thorand B, Tönjes A, Tremblay A, Tsafantakis E, van der Most PJ, Völker U, Vohl MC, Vonk JM, Waldenberger M, Walker RW, Wennauer R, Widén E, Willemsen G, Wilsgaard T, Wright AF, Zillikens MC, van Dijk SC, van Schoor NM, Asselbergs FW, de Bakker PI, Beckmann JS, Beilby J, Bennett DA, Bergman RN, Bergmann S, Böger CA, Boehm BO, Boerwinkle E, Boomsma DI, Bornstein SR, Bottinger EP, Bouchard C, Chambers JC, Chanock SJ, Chasman DI, Cucca F, Cusi D, Dedoussis G, Erdmann J, Eriksson JG, Evans DA, de Faire U, Farrall M, Ferrucci L, Ford I, Franke L, Franks PW, Froguel P, Gansevoort RT, Gieger C, Grönberg H, Gudnason V, Gyllensten U, Hall P, Hamsten A, van der Harst P, Hayward C, Heliövaara M, Hengstenberg C, Hicks AA, Hingorani A, Hofman A, Hu F, Huikuri HV, Hveem K, James AL, Jordan JM, Jula A, Kähönen M, Kajantie E, Kathiresan S, Kiemeney LA, Kivimaki M, Knekt PB, Koistinen HA, Kooner JS, Koskinen S, Kuusisto J, Maerz W, Martin NG, Laakso M, Lakka TA, Lehtimäki T, Lettre G, Levinson DF, Lind L, Lokki ML, Mäntyselkä P, Melbye M, Metspalu A, Mitchell BD, Moll FL, Murray JC, Musk AW, Nieminen MS, Njølstad I, Ohlsson C, Oldehinkel AJ, Oostra BA, Palmer LJ, Pankow JS, Pasterkamp G, Pedersen NL, Pedersen O, Penninx BW, Perola M, Peters A, Polašek O, Pramstaller PP, Psaty BM, Qi L, Quertermous T, Raitakari OT, Rankinen T, Rauramaa R, Ridker PM, Rioux JD, Rivadeneira F, Rotter JI, Rudan I, den Ruijter HM, Saltevo J, Sattar N, Schunkert H, Schwarz PE, Shuldiner AR, Sinisalo J, Snieder H, Sørensen TI, Spector TD, Staessen JA, Stefania B, Thorsteinsdottir U, Stumvoll M, Tardif JC, Tremoli E, Tuomilehto J, Uitterlinden AG, Uusitupa M, Verbeek AL, Vermeulen SH, Viikari JS, Vitart V, Völzke H, Vollenweider P, Waeber G, Walker M, Wallaschofski H, Wareham NJ, Watkins H, Zeggini E, Chakravarti A, Clegg DJ, Cupples LA, Gordon-Larsen P, Jaquish CE, Rao DC, Abecasis GR, Assimes TL, Barroso I, Berndt SI, Boehnke M, Deloukas P, Fox CS, Groop LC, Hunter DJ, Ingelsson E, Kaplan RC, McCarthy MI, Mohlke KL, O'Connell JR, Schlessinger D, Strachan DP, Stefansson K, van Duijn CM, Hirschhorn JN, Lindgren CM, Heid IM, North KE, Borecki IB, Kutalik Z, Loos RJ | 2015-10-01 | PLoS genetics | |
| DNA Methylation Landscapes of Human Fetal Development. | Slieker RC, Roost MS, van Iperen L, Suchiman HE, Tobi EW, Carlotti F, de Koning EJ, Slagboom PE, Heijmans BT, Chuva de Sousa Lopes SM | 2015-10-01 | PLoS genetics | |
| Familial Longevity Is Associated With Higher TSH Secretion and Strong TSH-fT3 Relationship. | Jansen SW, Roelfsema F, van der Spoel E, Akintola AA, Postmus I, Ballieux BE, Slagboom PE, Cobbaert CM, van der Grond J, Westendorp RG, Pijl H, van Heemst D | 2015-10-01 | The Journal of clinical endocrinology and metabolism | |
| Majority of drug-related problems identified during medication review are not associated with STOPP/START criteria. | Verdoorn S, Kwint HF, Faber A, Gussekloo J, Bouvy ML | 2015-10-01 | Drug-related problems, Elderly, Inappropriate prescribing, Medication review, Primary care, STOPP/START criteria | European journal of clinical pharmacology |
| Effect of Discontinuation of Antihypertensive Treatment in Elderly People on Cognitive Functioning–the DANTE Study Leiden: A Randomized Clinical Trial. | Moonen JE, Foster-Dingley JC, de Ruijter W, van der Grond J, Bertens AS, van Buchem MA, Gussekloo J, Middelkoop HA, Wermer MJ, Westendorp RG, de Craen AJ, van der Mast RC | 2015-10-01 | JAMA internal medicine | |
| Changes in geriatric rehabilitation: a national programme to improve quality of care. The Synergy and Innovation in Geriatric Rehabilitation study. | Holstege MS, Caljouw MA, Zekveld IG, van Balen R, de Groot AJ, van Haastregt JC, Schols JM, Hertogh CM, Gussekloo J, Achterberg WP | 2015-10-01 | care process, geriatric rehabilitation, health service delivery, national programme, quality of care | International journal of integrated care |
| Erratum to: Association between pain, neuropsychiatric symptoms, and physical function in dementia: a systematic review and meta-analysis. | van Dalen-Kok AH, Pieper M, de Waal M, Lukas A, Husebo BS, Achterberg WP | 2015-09-09 | BMC geriatrics | |
| A gain of function mutation in TNFRSF11B encoding osteoprotegerin causes osteoarthritis with chondrocalcinosis. | Ramos YF, Bos SD, van der Breggen R, Kloppenburg M, Ye K, Lameijer EW, Nelissen RG, Slagboom PE, Meulenbelt I | 2015-09-01 | Chondrocalcinosis, Epidemiology, Osteoarthritis | Annals of the rheumatic diseases |
| Population-specific genotype imputations using minimac or IMPUTE2. | van Leeuwen EM, Kanterakis A, Deelen P, Kattenberg MV, Slagboom PE, de Bakker PI, Wijmenga C, Swertz MA, Boomsma DI, van Duijn CM, Karssen LC, Hottenga JJ | 2015-09-01 | Nature protocols | |
| Ambulance Transfer in Case of Postpartum Hemorrhage after Birth in Primary Midwifery Care in The Netherlands: A Prospective Cohort Study. | Stolp I, Smit M, Luxemburg S, van den Akker T, de Waard J, van Roosmalen J, de Vos R | 2015-09-01 | midwifery, postpartum hemorrhage, primary care | Birth (Berkeley, Calif.) |
| Executive function, but not memory, associates with incident coronary heart disease and stroke. | Rostamian S, van Buchem MA, Westendorp RG, Jukema JW, Mooijaart SP, Sabayan B, de Craen AJ | 2015-09-01 | Neurology | |
| Increase in N-terminal pro-brain natriuretic peptide levels, renal function and cardiac disease in the oldest old. | Poortvliet R, de Craen A, Gussekloo J, de Ruijter W | 2015-09-01 | NT-proBNP, ageing (aged 80 and over), cardiovascular disease, heart failure, older people, renal function | Age and ageing |
| Association between changes in brain microstructure and cognition in older subjects at increased risk for vascular disease. | Sala M, de Roos A, Blauw GJ, Middelkoop HA, Jukema JW, Mooijaart SP, van Buchem MA, de Craen AJ, van der Grond J | 2015-08-07 | BMC neurology | |
| Underlying molecular mechanisms of DIO2 susceptibility in symptomatic osteoarthritis. | Bomer N, den Hollander W, Ramos YF, Bos SD, van der Breggen R, Lakenberg N, Pepers BA, van Eeden AE, Darvishan A, Tobi EW, Duijnisveld BJ, van den Akker EB, Heijmans BT, van Roon-Mom WM, Verbeek FJ, van Osch GJ, Nelissen RG, Slagboom PE, Meulenbelt I | 2015-08-01 | Annals of the rheumatic diseases | |
| Low tobacco-related cancer incidence in offspring of long-lived siblings: a comparison with Danish national cancer registry data. | Pedersen JK, Skytthe A, McGue M, Honig LS, Franceschi C, Kirkwood TB, Passarino G, Slagboom PE, Vaupel JW, Christensen K | 2015-08-01 | Cancer, Cohort study, Familial clustering, Lifestyle and aging, Longevity | Annals of epidemiology |
| Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome. | Tobi EW, Slieker RC, Stein AD, Suchiman HE, Slagboom PE, van Zwet EW, Heijmans BT, Lumey LH | 2015-08-01 | DNA methylation, prenatal, Dutch Famine, Hunger Winter, exposure, nutrition | International journal of epidemiology |
| Parameters of glucose metabolism and the aging brain: a magnetization transfer imaging study of brain macro- and micro-structure in older adults without diabetes. | Akintola AA, van den Berg A, Altmann-Schneider I, Jansen SW, van Buchem MA, Slagboom PE, Westendorp RG, van Heemst D, van der Grond J | 2015-08-01 | Age (Dordrecht, Netherlands) | |
| Activity of the Type II JAK2 Inhibitor CHZ868 in B Cell Acute Lymphoblastic Leukemia. | Wu SC, Li LS, Kopp N, Montero J, Chapuy B, Yoda A, Christie AL, Liu H, Christodoulou A, van Bodegom D, van der Zwet J, Layer JV, Tivey T, Lane AA, Ryan JA, Ng SY, DeAngelo DJ, Stone RM, Steensma D, Wadleigh M, Harris M, Mandon E, Ebel N, Andraos R, Romanet V, Dölemeyer A, Sterker D, Zender M, Rodig SJ, Murakami M, Hofmann F, Kuo F, Eck MJ, Silverman LB, Sallan SE, Letai A, Baffert F, Vangrevelinghe E, Radimerski T, Gaul C, Weinstock DM | 2015-07-13 | Cancer cell | |
| Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations. | Shah S, Bonder MJ, Marioni RE, Zhu Z, McRae AF, Zhernakova A, Harris SE, Liewald D, Henders AK, Mendelson MM, Liu C, Joehanes R, Liang L, Levy D, Martin NG, Starr JM, Wijmenga C, Wray NR, Yang J, Montgomery GW, Franke L, Deary IJ, Visscher PM | 2015-07-02 | American journal of human genetics | |
| Genome-wide patterns and properties of de novo mutations in humans. | Francioli LC, Polak PP, Koren A, Menelaou A, Chun S, Renkens I, van Duijn CM, Swertz M, Wijmenga C, van Ommen G, Slagboom PE, Boomsma DI, Ye K, Guryev V, Arndt PF, Kloosterman WP, de Bakker PIW, Sunyaev SR | 2015-07-01 | Nature genetics | |
| Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation. | Horikoshi M, Mӓgi R, van de Bunt M, Surakka I, Sarin AP, Mahajan A, Marullo L, Thorleifsson G, Hӓgg S, Hottenga JJ, Ladenvall C, Ried JS, Winkler TW, Willems SM, Pervjakova N, Esko T, Beekman M, Nelson CP, Willenborg C, Wiltshire S, Ferreira T, Fernandez J, Gaulton KJ, Steinthorsdottir V, Hamsten A, Magnusson PK, Willemsen G, Milaneschi Y, Robertson NR, Groves CJ, Bennett AJ, Lehtimӓki T, Viikari JS, Rung J, Lyssenko V, Perola M, Heid IM, Herder C, Grallert H, Müller-Nurasyid M, Roden M, Hypponen E, Isaacs A, van Leeuwen EM, Karssen LC, Mihailov E, Houwing-Duistermaat JJ, de Craen AJ, Deelen J, Havulinna AS, Blades M, Hengstenberg C, Erdmann J, Schunkert H, Kaprio J, Tobin MD, Samani NJ, Lind L, Salomaa V, Lindgren CM, Slagboom PE, Metspalu A, van Duijn CM, Eriksson JG, Peters A, Gieger C, Jula A, Groop L, Raitakari OT, Power C, Penninx BW, de Geus E, Smit JH, Boomsma DI, Pedersen NL, Ingelsson E, Thorsteinsdottir U, Stefansson K, Ripatti S, Prokopenko I, McCarthy MI, Morris AP | 2015-07-01 | PLoS genetics | |
| A Genome-Wide Association Study Identifies the Skin Color Genes IRF4, MC1R, ASIP, and BNC2 Influencing Facial Pigmented Spots. | Jacobs LC, Hamer MA, Gunn DA, Deelen J, Lall JS, van Heemst D, Uh HW, Hofman A, Uitterlinden AG, Griffiths CEM, Beekman M, Slagboom PE, Kayser M, Liu F, Nijsten T | 2015-07-01 | The Journal of investigative dermatology | |
| Women’s perceptions of the quality of emergency obstetric care in a referral hospital in rural Tanzania. | Stal KB, Pallangyo P, van Elteren M, van den Akker T, van Roosmalen J, Nyamtema A | 2015-07-01 | actitud trabajadores sanitarios, attitude des agents de santé, calidad de atención obstétrica, health workers' attitude, patient perception, percepción del paciente, perception du patient, quality of obstetric care, qualité des soins obstétricaux | Tropical medicine & international health : TM & IH |
| Intrinsic and extrinsic mortality reunited. | Koopman JJ, Wensink MJ, Rozing MP, van Bodegom D, Westendorp RG | 2015-07-01 | Aging, Extrinsic mortality, Gene–environment interaction, Intrinsic mortality, Partitioning of mortality | Experimental gerontology |
| Effect of tailored antibiotic stewardship programmes on the appropriateness of antibiotic prescribing in nursing homes. | van Buul LW, van der Steen JT, Achterberg WP, Schellevis FG, Essink RT, de Greeff SC, Natsch S, Sloane PD, Zimmerman S, Twisk JW, Veenhuizen RB, Hertogh CM | 2015-07-01 | appropriateness of prescribing decisions, guideline-adherent antibiotic selection, participatory action research | The Journal of antimicrobial chemotherapy |
| Human longevity is characterised by high thyroid stimulating hormone secretion without altered energy metabolism. | Jansen SW, Akintola AA, Roelfsema F, van der Spoel E, Cobbaert CM, Ballieux BE, Egri P, Kvarta-Papp Z, Gereben B, Fekete C, Slagboom PE, van der Grond J, Demeneix BA, Pijl H, Westendorp RG, van Heemst D | 2015-06-19 | Scientific reports | |
| Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels. | Draisma HHM, Pool R, Kobl M, Jansen R, Petersen AK, Vaarhorst AAM, Yet I, Haller T, Demirkan A, Esko T, Zhu G, Böhringer S, Beekman M, van Klinken JB, Römisch-Margl W, Prehn C, Adamski J, de Craen AJM, van Leeuwen EM, Amin N, Dharuri H, Westra HJ, Franke L, de Geus EJC, Hottenga JJ, Willemsen G, Henders AK, Montgomery GW, Nyholt DR, Whitfield JB, Penninx BW, Spector TD, Metspalu A, Slagboom PE, van Dijk KW, 't Hoen PAC, Strauch K, Martin NG, van Ommen GB, Illig T, Bell JT, Mangino M, Suhre K, McCarthy MI, Gieger C, Isaacs A, van Duijn CM, Boomsma DI | 2015-06-12 | Nature communications | |
| Developmental determinants in non-communicable chronic diseases and ageing. | Bousquet J, Anto JM, Berkouk K, Gergen P, Antunes JP, Augé P, Camuzat T, Bringer J, Mercier J, Best N, Bourret R, Akdis M, Arshad SH, Bedbrook A, Berr C, Bush A, Cavalli G, Charles MA, Clavel-Chapelon F, Gillman M, Gold DR, Goldberg M, Holloway JW, Iozzo P, Jacquemin S, Jeandel C, Kauffmann F, Keil T, Koppelman GH, Krauss-Etschmann S, Kuh D, Lehmann S, Carlsen KC, Maier D, Méchali M, Melén E, Moatti JP, Momas I, Nérin P, Postma DS, Ritchie K, Robine JM, Samolinski B, Siroux V, Slagboom PE, Smit HA, Sunyer J, Valenta R, Van de Perre P, Verdier JM, Vrijheid M, Wickman M, Yiallouros P, Zins M | 2015-06-01 | Asthma, COPD ÀÜ Mechanisms, Paediatric asthma | Thorax |
| Longitudinal weight differences, gene expression and blood biomarkers in BMI-discordant identical twins. | van Dongen J, Willemsen G, Heijmans BT, Neuteboom J, Kluft C, Jansen R, Penninx BW, Slagboom PE, de Geus EJ, Boomsma DI | 2015-06-01 | International journal of obesity (2005) | |
| The impact of low-frequency and rare variants on lipid levels. | Surakka I, Horikoshi M, Mägi R, Sarin AP, Mahajan A, Lagou V, Marullo L, Ferreira T, Miraglio B, Timonen S, Kettunen J, Pirinen M, Karjalainen J, Thorleifsson G, Hägg S, Hottenga JJ, Isaacs A, Ladenvall C, Beekman M, Esko T, Ried JS, Nelson CP, Willenborg C, Gustafsson S, Westra HJ, Blades M, de Craen AJ, de Geus EJ, Deelen J, Grallert H, Hamsten A, Havulinna AS, Hengstenberg C, Houwing-Duistermaat JJ, Hyppönen E, Karssen LC, Lehtimäki T, Lyssenko V, Magnusson PK, Mihailov E, Müller-Nurasyid M, Mpindi JP, Pedersen NL, Penninx BW, Perola M, Pers TH, Peters A, Rung J, Smit JH, Steinthorsdottir V, Tobin MD, Tsernikova N, van Leeuwen EM, Viikari JS, Willems SM, Willemsen G, Schunkert H, Erdmann J, Samani NJ, Kaprio J, Lind L, Gieger C, Metspalu A, Slagboom PE, Groop L, van Duijn CM, Eriksson JG, Jula A, Salomaa V, Boomsma DI, Power C, Raitakari OT, Ingelsson E, Järvelin MR, Thorsteinsdottir U, Franke L, Ikonen E, Kallioniemi O, Pietiäinen V, Lindgren CM, Stefansson K, Palotie A, McCarthy MI, Morris AP, Prokopenko I, Ripatti S | 2015-06-01 | Nature genetics | |
| Disentangling the effects of circulating IGF-1, glucose, and cortisol on features of perceived age. | van Drielen K, Gunn DA, Noordam R, Griffiths CE, Westendorp RG, de Craen AJ, van Heemst D | 2015-06-01 | Age (Dordrecht, Netherlands) | |
| Characteristics of de novo structural changes in the human genome. | Kloosterman WP, Francioli LC, Hormozdiari F, Marschall T, Hehir-Kwa JY, Abdellaoui A, Lameijer EW, Moed MH, Koval V, Renkens I, van Roosmalen MJ, Arp P, Karssen LC, Coe BP, Handsaker RE, Suchiman ED, Cuppen E, Thung DT, McVey M, Wendl MC, Uitterlinden A, van Duijn CM, Swertz MA, Wijmenga C, van Ommen GB, Slagboom PE, Boomsma DI, Schönhuth A, Eichler EE, de Bakker PI, Ye K, Guryev V | 2015-06-01 | Genome research | |
| Subclinical Hypothyroidism and the Risk of Stroke Events and Fatal Stroke: An Individual Participant Data Analysis. | Chaker L, Baumgartner C, den Elzen WP, Ikram MA, Blum MR, Collet TH, Bakker SJ, Dehghan A, Drechsler C, Luben RN, Hofman A, Portegies ML, Medici M, Iervasi G, Stott DJ, Ford I, Bremner A, Wanner C, Ferrucci L, Newman AB, Dullaart RP, Sgarbi JA, Ceresini G, Maciel RM, Westendorp RG, Jukema JW, Imaizumi M, Franklyn JA, Bauer DC, Walsh JP, Razvi S, Khaw KT, Cappola AR, Völzke H, Franco OH, Gussekloo J, Rodondi N, Peeters RP | 2015-06-01 | The Journal of clinical endocrinology and metabolism | |
| Thyroid function within the normal range and risk of coronary heart disease: an individual participant data analysis of 14 cohorts. | Åsvold BO, Vatten LJ, Bjøro T, Bauer DC, Bremner A, Cappola AR, Ceresini G, den Elzen WP, Ferrucci L, Franco OH, Franklyn JA, Gussekloo J, Iervasi G, Imaizumi M, Kearney PM, Khaw KT, Maciel RM, Newman AB, Peeters RP, Psaty BM, Razvi S, Sgarbi JA, Stott DJ, Trompet S, Vanderpump MP, Völzke H, Walsh JP, Westendorp RG, Rodondi N | 2015-06-01 | JAMA internal medicine | |
| Evidence-based medicine in older patients: how can we do better? | Mooijaart SP, Broekhuizen K, Trompet S, de Craen AJ, Gussekloo J, Oleksik A, van Heemst D, Blauw GJ, Muller M | 2015-06-01 | The Netherlands journal of medicine | |
| Association Between Glycosylated Hemoglobin and Cardiovascular Events and Mortality in Older Adults without Diabetes Mellitus in the General Population: The Leiden 85-Plus Study. | Birkenhäger-Gillesse EG, den Elzen WP, Achterberg WP, Mooijaart SP, Gussekloo J, de Craen AJ | 2015-06-01 | aged ≥ 80, cardiovascular disease, diabetes mellitus, glycosylated hemoglobin, mortality | Journal of the American Geriatrics Society |
| Subclinical thyroid dysfunction and fracture risk: a meta-analysis. | Blum MR, Bauer DC, Collet TH, Fink HA, Cappola AR, da Costa BR, Wirth CD, Peeters RP, Åsvold BO, den Elzen WP, Luben RN, Imaizumi M, Bremner AP, Gogakos A, Eastell R, Kearney PM, Strotmeyer ES, Wallace ER, Hoff M, Ceresini G, Rivadeneira F, Uitterlinden AG, Stott DJ, Westendorp RG, Khaw KT, Langhammer A, Ferrucci L, Gussekloo J, Williams GR, Walsh JP, Jüni P, Aujesky D, Rodondi N | 2015-05-26 | JAMA | |
| Transcriptional associations of osteoarthritis-mediated loss of epigenetic control in articular cartilage. | den Hollander W, Ramos YF, Bomer N, Elzinga S, van der Breggen R, Lakenberg N, de Dijcker WJ, Suchiman HE, Duijnisveld BJ, Houwing-Duistermaat JJ, Slagboom PE, Bos SD, Nelissen RG, Meulenbelt I | 2015-05-01 | Arthritis & rheumatology (Hoboken, N.J.) | |
| Visceral adipose tissue is associated with microstructural brain tissue damage. | Widya RL, Kroft LJ, Altmann-Schneider I, van den Berg-Huysmans AA, van der Bijl N, de Roos A, Lamb HJ, van Buchem MA, Slagboom PE, van Heemst D, van der Grond J | 2015-05-01 | Obesity (Silver Spring, Md.) | |
| Handgrip strength, ageing and mortality in rural Africa. | Koopman JJ, van Bodegom D, van Heemst D, Westendorp RG | 2015-05-01 | Africa, ageing, handgrip strength, mortality, older people | Age and ageing |
| Monochloroacetic acid application is an effective alternative to cryotherapy for common and plantar warts in primary care: a randomized controlled trial. | Bruggink SC, Gussekloo J, Egberts PF, Bavinck JNB, de Waal MWM, Assendelft WJJ, Eekhof JAH | 2015-05-01 | The Journal of investigative dermatology | |
| Development of a practice guideline for optimal symptom relief for patients with pneumonia and dementia in nursing homes using a Delphi study. | van der Maaden T, van der Steen JT, de Vet HC, Achterberg WP, Boersma F, Schols JM, van Berkel JF, Mehr DR, Arcand M, Hoepelman AI, Koopmans RT, Hertogh CM | 2015-05-01 | Delphi study, dementia, nursing homes, pneumonia, practice guideline, quality improvement | International journal of geriatric psychiatry |
| Association between pain, neuropsychiatric symptoms, and physical function in dementia: a systematic review and meta-analysis. | van Dalen-Kok AH, Pieper MJ, de Waal MW, Lukas A, Husebo BS, Achterberg WP | 2015-04-19 | BMC geriatrics | |
| Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI. | Verhaaren BF, Debette S, Bis JC, Smith JA, Ikram MK, Adams HH, Beecham AH, Rajan KB, Lopez LM, Barral S, van Buchem MA, van der Grond J, Smith AV, Hegenscheid K, Aggarwal NT, de Andrade M, Atkinson EJ, Beekman M, Beiser AS, Blanton SH, Boerwinkle E, Brickman AM, Bryan RN, Chauhan G, Chen CP, Chouraki V, de Craen AJ, Crivello F, Deary IJ, Deelen J, De Jager PL, Dufouil C, Elkind MS, Evans DA, Freudenberger P, Gottesman RF, Guðnason V, Habes M, Heckbert SR, Heiss G, Hilal S, Hofer E, Hofman A, Ibrahim-Verbaas CA, Knopman DS, Lewis CE, Liao J, Liewald DC, Luciano M, van der Lugt A, Martinez OO, Mayeux R, Mazoyer B, Nalls M, Nauck M, Niessen WJ, Oostra BA, Psaty BM, Rice KM, Rotter JI, von Sarnowski B, Schmidt H, Schreiner PJ, Schuur M, Sidney SS, Sigurdsson S, Slagboom PE, Stott DJ, van Swieten JC, Teumer A, Töglhofer AM, Traylor M, Trompet S, Turner ST, Tzourio C, Uh HW, Uitterlinden AG, Vernooij MW, Wang JJ, Wong TY, Wardlaw JM, Windham BG, Wittfeld K, Wolf C, Wright CB, Yang Q, Zhao W, Zijdenbos A, Jukema JW, Sacco RL, Kardia SL, Amouyel P, Mosley TH, Longstreth WT, DeCarli CC, van Duijn CM, Schmidt R, Launer LJ, Grabe HJ, Seshadri SS, Ikram MA, Fornage M | 2015-04-01 | cerebral small vessel diseases, cerebrovascular disorders, genome-wide association study, hypertension, leukoencephalopathies, polymorphisms, single nucleotide | Circulation. Cardiovascular genetics |
| LDL cholesterol still a problem in old age? A Mendelian randomization study. | Postmus I, Deelen J, Sedaghat S, Trompet S, de Craen AJ, Heijmans BT, Franco OH, Hofman A, Dehghan A, Slagboom PE, Westendorp RG, Jukema JW | 2015-04-01 | LDL-cholesterol, Mendelian randomization, genetic risk score, old age | International journal of epidemiology |
| Biological correlates of blood pressure variability in elderly at high risk of cardiovascular disease. | Poortvliet RK, Lloyd SM, Ford I, Sattar N, de Craen AJ, Wijsman LW, Mooijaart SP, Westendorp RG, Jukema JW, de Ruijter W, Gussekloo J, Stott DJ | 2015-04-01 | blood pressure, cardiovascular risk, correlates, hypertension, mortality, old age, variability. | American journal of hypertension |
| [TOPICS-MDS: a versatile resource for generating scientific and social knowledge for elderly care]. | van den Brink D, Lutomski JE, Qin L, den Elzen WP, Kempen GI, Krabbe PF, Steyerberg EW, Muntinga M, Moll van Charante EP, Bleijenberg N, Olde Rikkert MG, Melis RJ | 2015-04-01 | Tijdschrift voor gerontologie en geriatrie | |
| Repeat HIV testing during pregnancy and delivery: missed opportunities in a rural district hospital in Zambia. | Heemelaar S, Habets N, Makukula Z, van Roosmalen J, van den Akker T | 2015-03-01 | HIV, VIH, calidad de cuidados, cuidados prenatales, embarazo, grossesse, maternal and child health, pregnancy, prenatal care, quality of care, qualité des soins, salud materno-infantil, santé maternelle et de l'enfant, soins prénatals | Tropical medicine & international health : TM & IH |
| Quantification of structural cerebral abnormalities on MRI 18 months after aneurysmal subarachnoid hemorrhage in patients who received endovascular treatment. | de Bresser J, Schaafsma JD, Luitse MJ, Viergever MA, Rinkel GJ, Biessels GJ | 2015-03-01 | Neuroradiology | |
| Antibiotic prescribing in Dutch nursing homes: how appropriate is it? | van Buul LW, Veenhuizen RB, Achterberg WP, Schellevis FG, Essink RT, de Greeff SC, Natsch S, van der Steen JT, Hertogh CM | 2015-03-01 | Nursing homes, antibiotic prescribing, respiratory tract infection, urinary tract infection | Journal of the American Medical Directors Association |
| Chronic pain in “probable” vascular dementia: preliminary findings. | Scherder EJ, Plooij B, Achterberg WP, Pieper M, Wiegersma M, Lobbezoo F, Oosterman JM | 2015-03-01 | Central Neuropathic Pain, Pain Affect, Pain Intensity, Pain Treatment, Probable Vascular Dementia, White Matter Lesions | Pain medicine (Malden, Mass.) |
| Genetic studies of body mass index yield new insights for obesity biology. | Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J, Croteau-Chonka DC, Esko T, Fall T, Ferreira T, Gustafsson S, Kutalik Z, Luan J, Mägi R, Randall JC, Winkler TW, Wood AR, Workalemahu T, Faul JD, Smith JA, Zhao JH, Zhao W, Chen J, Fehrmann R, Hedman ÅK, Karjalainen J, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bolton JL, Bragg-Gresham JL, Buyske S, Demirkan A, Deng G, Ehret GB, Feenstra B, Feitosa MF, Fischer K, Goel A, Gong J, Jackson AU, Kanoni S, Kleber ME, Kristiansson K, Lim U, Lotay V, Mangino M, Leach IM, Medina-Gomez C, Medland SE, Nalls MA, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Shungin D, Stančáková A, Strawbridge RJ, Sung YJ, Tanaka T, Teumer A, Trompet S, van der Laan SW, van Setten J, Van Vliet-Ostaptchouk JV, Wang Z, Yengo L, Zhang W, Isaacs A, Albrecht E, Ärnlöv J, Arscott GM, Attwood AP, Bandinelli S, Barrett 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MM, Nolte IM, Pilz S, Rayner NW, Renstrom F, Rettig R, Ried JS, Ripke S, Robertson NR, Rose LM, Sanna S, Scharnagl H, Scholtens S, Schumacher FR, Scott WR, Seufferlein T, Shi J, Smith AV, Smolonska J, Stanton AV, Steinthorsdottir V, Stirrups K, Stringham HM, Sundström J, Swertz MA, Swift AJ, Syvänen AC, Tan ST, Tayo BO, Thorand B, Thorleifsson G, Tyrer JP, Uh HW, Vandenput L, Verhulst FC, Vermeulen SH, Verweij N, Vonk JM, Waite LL, Warren HR, Waterworth D, Weedon MN, Wilkens LR, Willenborg C, Wilsgaard T, Wojczynski MK, Wong A, Wright AF, Zhang Q, Brennan EP, Choi M, Dastani Z, Drong AW, Eriksson P, Franco-Cereceda A, Gådin JR, Gharavi AG, Goddard ME, Handsaker RE, Huang J, Karpe F, Kathiresan S, Keildson S, Kiryluk K, Kubo M, Lee JY, Liang L, Lifton RP, Ma B, McCarroll SA, McKnight AJ, Min JL, Moffatt MF, Montgomery GW, Murabito JM, Nicholson G, Nyholt DR, Okada Y, Perry JRB, Dorajoo R, Reinmaa E, Salem RM, Sandholm N, Scott RA, Stolk L, Takahashi A, Tanaka T, van 't Hooft FM, 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| New genetic loci link adipose and insulin biology to body fat distribution. | Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE, Workalemahu T, Wu JMW, Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C, Gustafsson S, Day FR, Esko T, Fall T, Kutalik Z, Luan J, Randall JC, Scherag A, Vedantam S, Wood AR, Chen J, Fehrmann R, Karjalainen J, Kahali B, Liu CT, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bragg-Gresham JL, Buyske S, Demirkan A, Ehret GB, Feitosa MF, Goel A, Jackson AU, Johnson T, Kleber ME, Kristiansson K, Mangino M, Leach IM, Medina-Gomez C, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Stančáková A, Sung YJ, Tanaka T, Teumer A, Van Vliet-Ostaptchouk JV, Yengo L, Zhang W, Albrecht E, Ärnlöv J, Arscott GM, Bandinelli S, Barrett A, Bellis C, Bennett AJ, Berne C, Blüher M, Böhringer S, Bonnet F, Böttcher Y, Bruinenberg M, Carba DB, Caspersen IH, Clarke R, Daw EW, Deelen J, Deelman E, Delgado G, Doney AS, Eklund N, Erdos MR, Estrada K, Eury E, Friedrich N, Garcia ME, Giedraitis V, Gigante B, Go AS, Golay A, Grallert H, Grammer TB, Gräßler J, Grewal J, Groves CJ, Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C, Heikkilä K, Herzig KH, Helmer Q, Hillege HL, Holmen O, Hunt SC, Isaacs A, Ittermann T, James AL, Johansson I, Juliusdottir T, Kalafati IP, Kinnunen L, Koenig W, Kooner IK, Kratzer W, Lamina C, Leander K, Lee NR, Lichtner P, Lind L, Lindström J, Lobbens S, Lorentzon M, Mach F, Magnusson PK, Mahajan A, McArdle WL, Menni C, Merger S, Mihailov E, Milani L, Mills R, Moayyeri A, Monda KL, Mooijaart SP, Mühleisen TW, Mulas A, Müller G, Müller-Nurasyid M, Nagaraja R, Nalls MA, Narisu N, Glorioso N, Nolte IM, Olden M, Rayner NW, Renstrom F, Ried JS, Robertson NR, Rose LM, Sanna S, Scharnagl H, Scholtens S, Sennblad B, Seufferlein T, Sitlani CM, Smith AV, Stirrups K, Stringham HM, Sundström J, Swertz MA, Swift AJ, Syvänen AC, Tayo BO, Thorand B, Thorleifsson G, Tomaschitz A, Troffa C, van Oort FV, Verweij N, Vonk JM, Waite LL, Wennauer R, Wilsgaard T, Wojczynski MK, Wong A, Zhang Q, Zhao JH, Brennan EP, Choi M, Eriksson P, Folkersen L, Franco-Cereceda A, Gharavi AG, Hedman ÅK, Hivert MF, Huang J, Kanoni S, Karpe F, Keildson S, Kiryluk K, Liang L, Lifton RP, Ma B, McKnight AJ, McPherson R, Metspalu A, Min JL, Moffatt MF, Montgomery GW, Murabito JM, Nicholson G, Nyholt DR, Olsson C, Perry JR, Reinmaa E, Salem RM, Sandholm N, Schadt EE, Scott RA, Stolk L, Vallejo EE, Westra HJ, Zondervan KT, Amouyel P, Arveiler D, Bakker SJ, Beilby J, Bergman RN, Blangero J, Brown MJ, Burnier M, Campbell H, Chakravarti A, Chines PS, Claudi-Boehm S, Collins FS, Crawford DC, Danesh J, de Faire U, de Geus EJ, Dörr M, Erbel R, Eriksson JG, Farrall M, Ferrannini E, Ferrières J, Forouhi NG, Forrester T, Franco OH, Gansevoort RT, Gieger C, Gudnason V, Haiman CA, Harris TB, Hattersley AT, Heliövaara M, Hicks AA, Hingorani AD, Hoffmann W, Hofman A, Homuth G, Humphries SE, Hyppönen E, Illig T, Jarvelin MR, Johansen B, Jousilahti P, Jula AM, Kaprio J, Kee F, Keinanen-Kiukaanniemi SM, Kooner JS, Kooperberg C, Kovacs P, Kraja AT, Kumari M, Kuulasmaa K, Kuusisto J, Lakka TA, Langenberg C, Le Marchand L, Lehtimäki T, Lyssenko V, Männistö S, Marette A, Matise TC, McKenzie CA, McKnight B, Musk AW, Möhlenkamp S, Morris AD, Nelis M, Ohlsson C, Oldehinkel AJ, Ong KK, Palmer LJ, Penninx BW, Peters A, Pramstaller PP, Raitakari OT, Rankinen T, Rao DC, Rice TK, Ridker PM, Ritchie MD, Rudan I, Salomaa V, Samani NJ, Saramies J, Sarzynski MA, Schwarz PE, Shuldiner AR, Staessen JA, Steinthorsdottir V, Stolk RP, Strauch K, Tönjes A, Tremblay A, Tremoli E, Vohl MC, Völker U, Vollenweider P, Wilson JF, Witteman JC, Adair LS, Bochud M, Boehm BO, Bornstein SR, Bouchard C, Cauchi S, Caulfield MJ, Chambers JC, Chasman DI, Cooper RS, Dedoussis G, Ferrucci L, Froguel P, Grabe HJ, Hamsten A, Hui J, Hveem K, Jöckel KH, Kivimaki M, Kuh D, Laakso M, Liu Y, März W, Munroe PB, Njølstad I, Oostra BA, Palmer CN, Pedersen NL, Perola M, Pérusse L, Peters U, Power C, Quertermous T, Rauramaa R, Rivadeneira F, Saaristo TE, Saleheen D, Sinisalo J, Slagboom PE, Snieder H, Spector TD, Stefansson K, Stumvoll M, Tuomilehto J, Uitterlinden AG, Uusitupa M, van der Harst P, Veronesi G, Walker M, Wareham NJ, Watkins H, Wichmann HE, Abecasis GR, Assimes TL, Berndt SI, Boehnke M, Borecki IB, Deloukas P, Franke L, Frayling TM, Groop LC, Hunter DJ, Kaplan RC, O'Connell JR, Qi L, Schlessinger D, Strachan DP, Thorsteinsdottir U, van Duijn CM, Willer CJ, Visscher PM, Yang J, Hirschhorn JN, Zillikens MC, McCarthy MI, Speliotes EK, North KE, Fox CS, Barroso I, Franks PW, Ingelsson E, Heid IM, Loos RJ, Cupples LA, Morris AP, Lindgren CM, Mohlke KL | 2015-02-12 | Nature | |
| DNA modification study of major depressive disorder: beyond locus-by-locus comparisons. | Oh G, Wang SC, Pal M, Chen ZF, Khare T, Tochigi M, Ng C, Yang YA, Kwan A, Kaminsky ZA, Mill J, Gunasinghe C, Tackett JL, Gottesman II, Willemsen G, de Geus EJC, Vink JM, Slagboom PE, Wray NR, Heath AC, Montgomery GW, Turecki G, Martin NG, Boomsma DI, McGuffin P, Kustra R, Petronis A | 2015-02-01 | DNA modification, Epigenetic outliers, Epigenetics, Heteroscedasticity, Major depressive disorder, Molecular networks | Biological psychiatry |
| International variation in GP treatment strategies for subclinical hypothyroidism in older adults: a case-based survey. | den Elzen WP, Lefèbre-van de Fliert AA, Virgini V, Mooijaart SP, Frey P, Kearney PM, Kerse N, Mallen CD, McCarthy VJ, Muth C, Rosemann T, Russell A, Schers H, Stott DJ, de Waal MW, Warner A, Westendorp RG, Rodondi N, Gussekloo J | 2015-02-01 | general practice, subclinical hypothyroidism, survey | The British journal of general practice : the journal of the Royal College of General Practitioners |
| Low thyroid function and anemia in old age: the Leiden 85-plus study. | den Elzen WP, de Craen AJ, Mooijaart SP, Gussekloo J | 2015-02-01 | Journal of the American Geriatrics Society | |
| Biological interpretation of genome-wide association studies using predicted gene functions. | Pers TH, Karjalainen JM, Chan Y, Westra HJ, Wood AR, Yang J, Lui JC, Vedantam S, Gustafsson S, Esko T, Frayling T, Speliotes EK, Boehnke M, Raychaudhuri S, Fehrmann RS, Hirschhorn JN, Franke L | 2015-01-19 | Nature communications | |
| GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy. | Broer L, Buchman AS, Deelen J, Evans DS, Faul JD, Lunetta KL, Sebastiani P, Smith JA, Smith AV, Tanaka T, Yu L, Arnold AM, Aspelund T, Benjamin EJ, De Jager PL, Eirkisdottir G, Evans DA, Garcia ME, Hofman A, Kaplan RC, Kardia SL, Kiel DP, Oostra BA, Orwoll ES, Parimi N, Psaty BM, Rivadeneira F, Rotter JI, Seshadri S, Singleton A, Tiemeier H, Uitterlinden AG, Zhao W, Bandinelli S, Bennett DA, Ferrucci L, Gudnason V, Harris TB, Karasik D, Launer LJ, Perls TT, Slagboom PE, Tranah GJ, Weir DR, Newman AB, van Duijn CM, Murabito JM | 2015-01-01 | APOE., FOXO3, GWAS, Longevity | The journals of gerontology. Series A, Biological sciences and medical sciences |
| Exome and whole genome sequencing in aging and longevity. | van den Akker EB, Deelen J, Slagboom PE, Beekman M | 2015-01-01 | Advances in experimental medicine and biology | |
| Design, measurement and processing of region-specific DNA methylation assays: the mass spectrometry-based method EpiTYPER. | Suchiman HE, Slieker RC, Kremer D, Slagboom PE, Heijmans BT, Tobi EW | 2015-01-01 | DNA methylation, EpiTYPER®, bisulfite, mass spectrometry, quantitative, region-specific | Frontiers in genetics |
| Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. | Bis JC, Sitlani C, Irvin R, Avery CL, Smith AV, Sun F, Evans DS, Musani SK, Li X, Trompet S, Krijthe BP, Harris TB, Quibrera PM, Brody JA, Demissie S, Davis BR, Wiggins KL, Tranah GJ, Lange LA, Sotoodehnia N, Stott DJ, Franco OH, Launer LJ, Stürmer T, Taylor KD, Cupples LA, Eckfeldt JH, Smith NL, Liu Y, Wilson JG, Heckbert SR, Buckley BM, Ikram MA, Boerwinkle E, Chen YD, de Craen AJ, Uitterlinden AG, Rotter JI, Ford I, Hofman A, Sattar N, Slagboom PE, Westendorp RG, Gudnason V, Vasan RS, Lumley T, Cummings SR, Taylor HA, Post W, Jukema JW, Stricker BH, Whitsel EA, Psaty BM, Arnett D | 2015-01-01 | PloS one | |
| Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C. | van Leeuwen EM, Huffman JE, Bis JC, Isaacs A, Mulder M, Sabo A, Smith AV, Demissie S, Manichaikul A, Brody JA, Feitosa MF, Duan Q, Schraut KE, Navarro P, van Vliet-Ostaptchouk JV, Zhu G, Mbarek H, Trompet S, Verweij N, Lyytikäinen LP, Deelen J, Nolte IM, van der Laan SW, Davies G, Vermeij-Verdoold AJ, van Oosterhout AA, Vergeer-Drop JM, Arking DE, Trochet H, Medina-Gomez C, Rivadeneira F, Uitterlinden AG, Dehghan A, Franco OH, Sijbrands EJ, Hofman A, White CC, Mychaleckyj JC, Peloso GM, Swertz MA, Willemsen G, de Geus EJ, Milaneschi Y, Penninx BW, Ford I, Buckley BM, de Craen AJ, Starr JM, Deary IJ, Pasterkamp G, Oldehinkel AJ, Snieder H, Slagboom PE, Nikus K, Kähönen M, Lehtimäki T, Viikari JS, Raitakari OT, van der Harst P, Jukema JW, Hottenga JJ, Boomsma DI, Whitfield JB, Montgomery G, Martin NG, Polasek O, Vitart V, Hayward C, Kolcic I, Wright AF, Rudan I, Joshi PK, Wilson JF, Lange LA, Wilson JG, Gudnason V, Harris TB, Morrison AC, Borecki IB, Rich SS, Padmanabhan S, Psaty BM, Rotter JI, Smith BH, Boerwinkle E, Cupples LA, van Duijn C | 2015-01-01 | NPJ aging and mechanisms of disease | |
| Lifestyle and youthful looks. | Gunn DA, Dick JL, van Heemst D, Griffiths CE, Tomlin CC, Murray PG, Griffiths TW, Ogden S, Mayes AE, Westendorp RG, Slagboom PE, de Craen AJ | 2015-01-01 | The British journal of dermatology | |
| Insulin, aging, and the brain: mechanisms and implications. | Akintola AA, van Heemst D | 2015-01-01 | accelerated aging, brain, delayed aging, inflammation, insulin, insulin receptors, longevity | Frontiers in endocrinology |
| Associations between insulin action and integrity of brain microstructure differ with familial longevity and with age. | Akintola AA, van den Berg A, van Buchem MA, Jansen SW, Slagboom EP, Westendorp RG, van der Grond J, van Heemst D | 2015-01-01 | Magnetic Resonance Imaging (MRI), Magnetization Transfer Imaging (MTI), age, brain, familial longevity, glucose, insulin | Frontiers in aging neuroscience |
| A simple and versatile method for frequent 24 h blood sample collection in healthy older adults. | Akintola AA, Jansen SW, Wilde RB, Hultzer G, Rodenburg R, van Heemst D | 2015-01-01 | Aging, Hormones, Repeated 24 h blood sampling, Sampling frequency | MethodsX |
| Characterization of the Hypothalamic-Pituitary-Adrenal-Axis in Familial Longevity under Resting Conditions. | Jansen SW, Roelfsema F, Akintola AA, Oei NY, Cobbaert CM, Ballieux BE, van der Grond J, Westendorp RG, Pijl H, van Heemst D | 2015-01-01 | PloS one | |
| IL7R gene expression network associates with human healthy ageing. | Passtoors WM, van den Akker EB, Deelen J, Maier AB, van der Breggen R, Jansen R, Trompet S, van Heemst D, Derhovanessian E, Pawelec G, van Ommen GJ, Slagboom PE, Beekman M | 2015-01-01 | Gene expression, Healthy ageing, IL7R | Immunity & ageing : I & A |
| Heart rate variability, but not heart rate, is associated with handgrip strength and mortality in older Africans at very low cardiovascular risk: A population-based study. | Koopman JJ, van Bodegom D, Maan AC, Li Z, Ziem JB, Westendorp RG, Jukema JW | 2015-01-01 | Ageing, Handgrip strength, Heart rate, Heart rate variability, Mortality | International journal of cardiology |
| Subclinical hypothyroidism and cognitive function in people over 60 years: a systematic review and meta-analysis. | Akintola AA, Jansen SW, van Bodegom D, van der Grond J, Westendorp RG, de Craen AJ, van Heemst D | 2015-01-01 | cognition, elderly, meta-analysis, subclinical hypothyroidism, systematic review | Frontiers in aging neuroscience |
| Seasonal Variation in Mortality, Medical Care Expenditure and Institutionalization in Older People: Evidence from a Dutch Cohort of Older Health Insurance Clients. | Rolden HJ, Rohling JH, van Bodegom D, Westendorp RG | 2015-01-01 | PloS one | |
| The Trade-Off between Female Fertility and Longevity during the Epidemiological Transition in the Netherlands. | Kaptijn R, Thomese F, Liefbroer AC, Van Poppel F, Van Bodegom D, Westendorp RG | 2015-01-01 | PloS one | |
| An in vivo study on brain microstructure in biological and chronological ageing. | Altmann-Schneider I, de Craen AJ, van den Berg-Huysmans AA, Slagboom P, Westendorp RG, van Buchem MA, van der Grond J | 2015-01-01 | PloS one | |
| Characteristics of randomized controlled trials designed for elderly: a systematic review. | Broekhuizen K, Pothof A, de Craen AJ, Mooijaart SP | 2015-01-01 | PloS one | |
| User preferences and usability of iVitality: optimizing an innovative online research platform for home-based health monitoring. | van Osch M, Rövekamp A, Bergman-Agteres SN, Wijsman LW, Ooms SJ, Mooijaart SP, Vermeulen J | 2015-01-01 | dementia, e-health, m-health, patient preferences, self-monitoring, technology, usability | Patient preference and adherence |
| Accuracy of Continuous Glucose Monitoring Measurements in Normo-Glycemic Individuals. | Akintola AA, Noordam R, Jansen SW, de Craen AJ, Ballieux BE, Cobbaert CM, Mooijaart SP, Pijl H, Westendorp RG, van Heemst D | 2015-01-01 | PloS one | |
| High prevalence of cutaneous warts in elementary school children and the ubiquitous presence of wart-associated human papillomavirus on clinically normal skin. | de Koning MN, Quint KD, Bruggink SC, Gussekloo J, Bouwes Bavinck JN, Feltkamp MC, Quint WG, Eekhof JA | 2015-01-01 | The British journal of dermatology | |
| Consequences of interaction of functional, somatic, mental and social problems in community-dwelling older people. | van Houwelingen AH, den Elzen WP, le Cessie S, Blom JW, Gussekloo J | 2015-01-01 | PloS one | |
| [Medication review in older people: identification of a new risk group]. | Tomaes LC, Poortvliet RK, Kwint HF, Gussekloo J | 2015-01-01 | Nederlands tijdschrift voor geneeskunde | |
| Correction: Predictive Value of a Profile of Routine Blood Measurements on Mortality in Older Persons in the General Population: The Leiden 85-Plus Study. | van Houwelingen AH, den Elzen WP, Mooijaart SP, Heijmans M, Blom JW, de Craen AJ, Gussekloo J | 2015-01-01 | PloS one | |
| [A treatment plan as method and compass]. | Wind AW, Gussekloo J | 2015-01-01 | Nederlands tijdschrift voor geneeskunde | |
| Variation in treatment strategies of Swiss general practitioners for subclinical hypothyroidism in older adults. | Baumgartner C, den Elzen WP, Blum MR, Coslovsky M, Streit S, Frey P, Herzig L, Haller DM, Mooijaart SP, Bischoff T, Rosemann T, Gussekloo J, Rodondi N | 2015-01-01 | Swiss medical weekly | |
| Self-Reported Hindering Health Complaints of Community-Dwelling Older Persons: A Cross-Sectional Study. | van Blijswijk SC, Chan OY, van Houwelingen AH, Gussekloo J, den Elzen WP, Blom JW | 2015-01-01 | PloS one | |
| Drug prescription rates in secondary cardiovascular prevention in old age: Do vulnerability and severity of the history of cardiovascular disease matter? | van Peet PG, Gussekloo J, den Elzen WP, Blom JW, de Waal MW, de Ruijter W | 2015-01-01 | Cardiovascular diseases, drug prescriptions, general practice, old age, secondary prevention, the Netherlands, vulnerability | Scandinavian journal of primary health care |
| Hippocampal disconnection in early Alzheimer’s disease: a 7 tesla MRI study. | Wisse LE, Reijmer YD, ter Telgte A, Kuijf HJ, Leemans A, Luijten PR, Koek HL, Geerlings MI, Biessels GJ | 2015-01-01 | Alzheimer's disease, diffusion magnetic resonance imaging, fornix, hippocampus, mild cognitive impairment, subiculum | Journal of Alzheimer's disease : JAD |
| MRBrainS Challenge: Online Evaluation Framework for Brain Image Segmentation in 3T MRI Scans. | Mendrik AM, Vincken KL, Kuijf HJ, Breeuwer M, Bouvy WH, de Bresser J, Alansary A, de Bruijne M, Carass A, El-Baz A, Jog A, Katyal R, Khan AR, van der Lijn F, Mahmood Q, Mukherjee R, van Opbroek A, Paneri S, Pereira S, Persson M, Rajchl M, Sarikaya D, Smedby Ö, Silva CA, Vrooman HA, Vyas S, Wang C, Zhao L, Biessels GJ, Viergever MA | 2015-01-01 | Computational intelligence and neuroscience | |
| Reliability and validity of the Falls Efficacy Scale-International after hip fracture in patients aged ≥ 65 years. | Visschedijk JH, Terwee CB, Caljouw MA, Spruit-van Eijk M, van Balen R, Achterberg WP | 2015-01-01 | Falls Efficacy Scale-International, fear of falling, hip fractures, measurement properties | Disability and rehabilitation |
| [Cost-effectiveness research in elderly residents in long-term care: prevention is better than cure, but not always cheaper]. | Achterberg WP, Gussekloo J, van den Hout WB | 2015-01-01 | Nederlands tijdschrift voor geneeskunde | |
| Factors influencing antibiotic prescribing in long-term care facilities: a qualitative in-depth study. | van Buul LW, van der Steen JT, Doncker SM, Achterberg WP, Schellevis FG, Veenhuizen RB, Hertogh CM | 2014-12-16 | BMC geriatrics | |
| Dose-response effects of a Web-based physical activity program on body composition and metabolic health in inactive older adults: additional analyses of a randomized controlled trial. | Vroege DP, Wijsman CA, Broekhuizen K, de Craen AJ, van Heemst D, van der Ouderaa FJ, van Mechelen W, Slagboom PE, Catt M, Westendorp RG, Verhagen EA, Mooijaart SP | 2014-12-04 | Internet, aging, metabolism, physical activity | Journal of medical Internet research |
| A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip. | Evangelou E, Kerkhof HJ, Styrkarsdottir U, Ntzani EE, Bos SD, Esko T, Evans DS, Metrustry S, Panoutsopoulou K, Ramos YF, Thorleifsson G, Tsilidis KK, Arden N, Aslam N, Bellamy N, Birrell F, Blanco FJ, Carr A, Chapman K, Day-Williams AG, Deloukas P, Doherty M, Engström G, Helgadottir HT, Hofman A, Ingvarsson T, Jonsson H, Keis A, Keurentjes JC, Kloppenburg M, Lind PA, McCaskie A, Martin NG, Milani L, Montgomery GW, Nelissen RG, Nevitt MC, Nilsson PM, Ollier WE, Parimi N, Rai A, Ralston SH, Reed MR, Riancho JA, Rivadeneira F, Rodriguez-Fontenla C, Southam L, Thorsteinsdottir U, Tsezou A, Wallis GA, Wilkinson JM, Gonzalez A, Lane NE, Lohmander LS, Loughlin J, Metspalu A, Uitterlinden AG, Jonsdottir I, Stefansson K, Slagboom PE, Zeggini E, Meulenbelt I, Ioannidis JP, Spector TD, van Meurs JB, Valdes AM | 2014-12-01 | Epidemiology, Gene Polymorphism, Osteoarthritis | Annals of the rheumatic diseases |
| MethylAid: visual and interactive quality control of large Illumina 450k datasets. | van Iterson M, Tobi EW, Slieker RC, den Hollander W, Luijk R, Slagboom PE, Heijmans BT | 2014-12-01 | Bioinformatics (Oxford, England) | |
| Associations between age and gray matter volume in anatomical brain networks in middle-aged to older adults. | Hafkemeijer A, Altmann-Schneider I, de Craen AJ, Slagboom PE, van der Grond J, Rombouts SA | 2014-12-01 | aging, atrophy, brain, gray matter, magnetic resonance imaging, structural covariance networks | Aging cell |
| Knee and hip articular cartilage have distinct epigenomic landscapes: implications for future cartilage regeneration approaches. | den Hollander W, Ramos YF, Bos SD, Bomer N, van der Breggen R, Lakenberg N, de Dijcker WJ, Duijnisveld BJ, Slagboom PE, Nelissen RG, Meulenbelt I | 2014-12-01 | Chondrocytes, Gene Polymorphism, Osteoarthritis | Annals of the rheumatic diseases |
| A common mineralocorticoid receptor polymorphism (I180V) interacts with life events in relation to perfectionism in eating disorders: a pilot study. | Slof-Op't Landt MC, DeRijk RH, van Son GE, Suchiman HE, Meulenbelt I, Slagboom PE, Van Furth EF | 2014-11-01 | G×E interactions, eating disorder, life events, mineralocorticoid receptor, perfectionism | European eating disorders review : the journal of the Eating Disorders Association |
| Defining the role of common variation in the genomic and biological architecture of adult human height. | Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K, Luan J, Kutalik Z, Amin N, Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y, Fall T, Fehrmann R, Ferreira T, Jackson AU, Karjalainen J, Lo KS, Locke AE, Mägi R, Mihailov E, Porcu E, Randall JC, Scherag A, Vinkhuyzen AA, Westra HJ, Winkler TW, Workalemahu T, Zhao JH, Absher D, Albrecht E, Anderson D, Baron J, Beekman M, Demirkan A, Ehret GB, Feenstra B, Feitosa MF, Fischer K, Fraser RM, Goel A, Gong J, Justice AE, Kanoni S, Kleber ME, Kristiansson K, Lim U, Lotay V, Lui JC, Mangino M, Mateo Leach I, Medina-Gomez C, Nalls MA, Nyholt DR, Palmer CD, Pasko D, Pechlivanis S, Prokopenko I, Ried JS, Ripke S, Shungin D, Stancáková A, Strawbridge RJ, Sung YJ, Tanaka T, Teumer A, Trompet S, van der Laan SW, van Setten J, Van Vliet-Ostaptchouk JV, Wang Z, Yengo L, Zhang W, Afzal U, Arnlöv J, Arscott GM, Bandinelli S, Barrett A, Bellis C, Bennett AJ, Berne C, Blüher M, Bolton JL, Böttcher Y, Boyd HA, Bruinenberg M, Buckley BM, Buyske S, Caspersen IH, Chines PS, Clarke R, Claudi-Boehm S, Cooper M, Daw EW, De Jong PA, Deelen J, Delgado G, Denny JC, Dhonukshe-Rutten R, Dimitriou M, Doney AS, Dörr M, Eklund N, Eury E, Folkersen L, Garcia ME, Geller F, Giedraitis V, Go AS, Grallert H, Grammer TB, Gräßler J, Grönberg H, de Groot LC, Groves CJ, Haessler J, Hall P, Haller T, Hallmans G, Hannemann A, Hartman CA, Hassinen M, Hayward C, Heard-Costa NL, Helmer Q, Hemani G, Henders AK, Hillege HL, Hlatky MA, Hoffmann W, Hoffmann P, Holmen O, Houwing-Duistermaat JJ, Illig T, Isaacs A, James AL, Jeff J, Johansen B, Johansson Å, Jolley J, Juliusdottir T, Junttila J, Kho AN, Kinnunen L, Klopp N, Kocher T, Kratzer W, Lichtner P, Lind L, Lindström J, Lobbens S, Lorentzon M, Lu Y, Lyssenko V, Magnusson PK, Mahajan A, Maillard M, McArdle WL, McKenzie CA, McLachlan S, McLaren PJ, Menni C, Merger S, Milani L, Moayyeri A, Monda KL, Morken MA, Müller G, Müller-Nurasyid M, Musk AW, Narisu N, Nauck M, Nolte IM, Nöthen MM, Oozageer L, Pilz S, Rayner NW, Renstrom F, Robertson NR, Rose LM, Roussel R, Sanna S, Scharnagl H, Scholtens S, Schumacher FR, Schunkert H, Scott RA, Sehmi J, Seufferlein T, Shi J, Silventoinen K, Smit JH, Smith AV, Smolonska J, Stanton AV, Stirrups K, Stott DJ, Stringham HM, Sundström J, Swertz MA, Syvänen AC, Tayo BO, Thorleifsson G, Tyrer JP, van Dijk S, van Schoor NM, van der Velde N, van Heemst D, van Oort FV, Vermeulen SH, Verweij N, Vonk JM, Waite LL, Waldenberger M, Wennauer R, Wilkens LR, Willenborg C, Wilsgaard T, Wojczynski MK, Wong A, Wright AF, Zhang Q, Arveiler D, Bakker SJ, Beilby J, Bergman RN, Bergmann S, Biffar R, Blangero J, Boomsma DI, Bornstein SR, Bovet P, Brambilla P, Brown MJ, Campbell H, Caulfield MJ, Chakravarti A, Collins R, Collins FS, Crawford DC, Cupples LA, Danesh J, de Faire U, den Ruijter HM, Erbel R, Erdmann J, Eriksson JG, Farrall M, Ferrannini E, Ferrières J, Ford I, Forouhi NG, Forrester T, Gansevoort RT, Gejman PV, Gieger C, Golay A, Gottesman O, Gudnason V, Gyllensten U, Haas DW, Hall AS, Harris TB, Hattersley AT, Heath AC, Hengstenberg C, Hicks AA, Hindorff LA, Hingorani AD, Hofman A, Hovingh GK, Humphries SE, Hunt SC, Hypponen E, Jacobs KB, Jarvelin MR, Jousilahti P, Jula AM, Kaprio J, Kastelein JJ, Kayser M, Kee F, Keinanen-Kiukaanniemi SM, Kiemeney LA, Kooner JS, Kooperberg C, Koskinen S, Kovacs P, Kraja AT, Kumari M, Kuusisto J, Lakka TA, Langenberg C, Le Marchand L, Lehtimäki T, Lupoli S, Madden PA, Männistö S, Manunta P, Marette A, Matise TC, McKnight B, Meitinger T, Moll FL, Montgomery GW, Morris AD, Morris AP, Murray JC, Nelis M, Ohlsson C, Oldehinkel AJ, Ong KK, Ouwehand WH, Pasterkamp G, Peters A, Pramstaller PP, Price JF, Qi L, Raitakari OT, Rankinen T, Rao DC, Rice TK, Ritchie M, Rudan I, Salomaa V, Samani NJ, Saramies J, Sarzynski MA, Schwarz PE, Sebert S, Sever P, Shuldiner AR, Sinisalo J, Steinthorsdottir V, Stolk RP, Tardif JC, Tönjes A, Tremblay A, Tremoli E, Virtamo J, Vohl MC, Amouyel P, Asselbergs FW, Assimes TL, Bochud M, Boehm BO, Boerwinkle E, Bottinger EP, Bouchard C, Cauchi S, Chambers JC, Chanock SJ, Cooper RS, de Bakker PI, Dedoussis G, Ferrucci L, Franks PW, Froguel P, Groop LC, Haiman CA, Hamsten A, Hayes MG, Hui J, Hunter DJ, Hveem K, Jukema JW, Kaplan RC, Kivimaki M, Kuh D, Laakso M, Liu Y, Martin NG, März W, Melbye M, Moebus S, Munroe PB, Njølstad I, Oostra BA, Palmer CN, Pedersen NL, Perola M, Pérusse L, Peters U, Powell JE, Power C, Quertermous T, Rauramaa R, Reinmaa E, Ridker PM, Rivadeneira F, Rotter JI, Saaristo TE, Saleheen D, Schlessinger D, Slagboom PE, Snieder H, Spector TD, Strauch K, Stumvoll M, Tuomilehto J, Uusitupa M, van der Harst P, Völzke H, Walker M, Wareham NJ, Watkins H, Wichmann HE, Wilson JF, Zanen P, Deloukas P, Heid IM, Lindgren CM, Mohlke KL, Speliotes EK, Thorsteinsdottir U, Barroso I, Fox CS, North KE, Strachan DP, Beckmann JS, Berndt SI, Boehnke M, Borecki IB, McCarthy MI, Metspalu A, Stefansson K, Uitterlinden AG, van Duijn CM, Franke L, Willer CJ, Price AL, Lettre G, Loos RJ, Weedon MN, Ingelsson E, O'Connell JR, Abecasis GR, Chasman DI, Goddard ME, Visscher PM, Hirschhorn JN, Frayling TM | 2014-11-01 | Nature genetics | |
| Variation in the costs of dying and the role of different health services, socio-demographic characteristics, and preceding health care expenses. | Rolden HJ, van Bodegom D, Westendorp RG | 2014-11-01 | Costs of dying, Health care expenditure, Hospital costs, Long-term care, Netherlands, Old age mortality, Population ageing, Proximity to death | Social science & medicine (1982) |
| Cochrane corner: is integrated disease management for patients with COPD effective? | Kruis AL, Smidt N, Assendelft WJ, Gussekloo J, Boland MR, Rutten-van Mölken M, Chavannes NH | 2014-11-01 | COPD epidemiology | Thorax |
| Cost-Effectiveness of a COPD Disease Management Program in Primary Care: The Recode Cluster Randomized Trial. | Boland MR, Kruis A, Tsiachristas A, Assendelft W, Gussekloo J, Blom C, Chavannes N, Rutten van-Molken M | 2014-11-01 | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research | |
| Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. | Postmus I, Trompet S, Deshmukh HA, Barnes MR, Li X, Warren HR, Chasman DI, Zhou K, Arsenault BJ, Donnelly LA, Wiggins KL, Avery CL, Griffin P, Feng Q, Taylor KD, Li G, Evans DS, Smith AV, de Keyser CE, Johnson AD, de Craen AJ, Stott DJ, Buckley BM, Ford I, Westendorp RG, Slagboom PE, Sattar N, Munroe PB, Sever P, Poulter N, Stanton A, Shields DC, O'Brien E, Shaw-Hawkins S, Chen YD, Nickerson DA, Smith JD, Dubé MP, Boekholdt SM, Hovingh GK, Kastelein JJ, McKeigue PM, Betteridge J, Neil A, Durrington PN, Doney A, Carr F, Morris A, McCarthy MI, Groop L, Ahlqvist E, Bis JC, Rice K, Smith NL, Lumley T, Whitsel EA, Stürmer T, Boerwinkle E, Ngwa JS, O'Donnell CJ, Vasan RS, Wei WQ, Wilke RA, Liu CT, Sun F, Guo X, Heckbert SR, Post W, Sotoodehnia N, Arnold AM, Stafford JM, Ding J, Herrington DM, Kritchevsky SB, Eiriksdottir G, Launer LJ, Harris TB, Chu AY, Giulianini F, MacFadyen JG, Barratt BJ, Nyberg F, Stricker BH, Uitterlinden AG, Hofman A, Rivadeneira F, Emilsson V, Franco OH, Ridker PM, Gudnason V, Liu Y, Denny JC, Ballantyne CM, Rotter JI, Adrienne Cupples L, Psaty BM, Palmer CN, Tardif JC, Colhoun HM, Hitman G, Krauss RM, Wouter Jukema J, Caulfield MJ | 2014-10-28 | Nature communications | |
| Genes expressed in blood link osteoarthritis with apoptotic pathways. | Ramos YF, Bos SD, Lakenberg N, Böhringer S, den Hollander WJ, Kloppenburg M, Slagboom PE, Meulenbelt I | 2014-10-01 | Epidemiology, Osteoarthritis, Outcomes research | Annals of the rheumatic diseases |
| A genome-wide association study of anorexia nervosa. | Boraska V, Franklin CS, Floyd JA, Thornton LM, Huckins LM, Southam L, Rayner NW, Tachmazidou I, Klump KL, Treasure J, Lewis CM, Schmidt U, Tozzi F, Kiezebrink K, Hebebrand J, Gorwood P, Adan RA, Kas MJ, Favaro A, Santonastaso P, Fernández-Aranda F, Gratacos M, Rybakowski F, Dmitrzak-Weglarz M, Kaprio J, Keski-Rahkonen A, Raevuori A, Van Furth EF, Slof-Op 't Landt MC, Hudson JI, Reichborn-Kjennerud T, Knudsen GP, Monteleone P, Kaplan AS, Karwautz A, Hakonarson H, Berrettini WH, Guo Y, Li D, Schork NJ, Komaki G, Ando T, Inoko H, Esko T, Fischer K, Männik K, Metspalu A, Baker JH, Cone RD, Dackor J, DeSocio JE, Hilliard CE, O'Toole JK, Pantel J, Szatkiewicz JP, Taico C, Zerwas S, Trace SE, Davis OS, Helder S, Bühren K, Burghardt R, de Zwaan M, Egberts K, Ehrlich S, Herpertz-Dahlmann B, Herzog W, Imgart H, Scherag A, Scherag S, Zipfel S, Boni C, Ramoz N, Versini A, Brandys MK, Danner UN, de Kovel C, Hendriks J, Koeleman BP, Ophoff RA, Strengman E, van Elburg AA, Bruson A, Clementi M, Degortes D, Forzan M, Tenconi E, Docampo E, Escaramís G, Jiménez-Murcia S, Lissowska J, Rajewski A, Szeszenia-Dabrowska N, Slopien A, Hauser J, Karhunen L, Meulenbelt I, Slagboom PE, Tortorella A, Maj M, Dedoussis G, Dikeos D, Gonidakis F, Tziouvas K, Tsitsika A, Papezova H, Slachtova L, Martaskova D, Kennedy JL, Levitan RD, Yilmaz Z, Huemer J, Koubek D, Merl E, Wagner G, Lichtenstein P, Breen G, Cohen-Woods S, Farmer A, McGuffin P, Cichon S, Giegling I, Herms S, Rujescu D, Schreiber S, Wichmann HE, Dina C, Sladek R, Gambaro G, Soranzo N, Julia A, Marsal S, Rabionet R, Gaborieau V, Dick DM, Palotie A, Ripatti S, Widén E, Andreassen OA, Espeseth T, Lundervold A, Reinvang I, Steen VM, Le Hellard S, Mattingsdal M, Ntalla I, Bencko V, Foretova L, Janout V, Navratilova M, Gallinger S, Pinto D, Scherer SW, Aschauer H, Carlberg L, Schosser A, Alfredsson L, Ding B, Klareskog L, Padyukov L, Courtet P, Guillaume S, Jaussent I, Finan C, Kalsi G, Roberts M, Logan DW, Peltonen L, Ritchie GR, Barrett JC, Estivill X, Hinney A, Sullivan PF, Collier DA, Zeggini E, Bulik CM | 2014-10-01 | Molecular psychiatry | |
| Variants of the IL-10 gene associate with muscle strength in elderly from rural Africa: a candidate gene study. | Beenakker KG, Koopman JJ, van Bodegom D, Kuningas M, Slagboom PE, Meij JJ, Maier AB, Westendorp RG | 2014-10-01 | Africa, IL-10 gene, cytokine production, innate immunity, muscle strength | Aging cell |
| Cerebral microvascular lesions on high-resolution 7-Tesla MRI in patients with type 2 diabetes. | Brundel M, Reijmer YD, van Veluw SJ, Kuijf HJ, Luijten PR, Kappelle LJ, Biessels GJ | 2014-10-01 | Diabetes | |
| A postal screener for pain and need for treatment in older persons in primary care. | de Waal MW, den Elzen WP, Achterberg WP, Gussekloo J, Blom JW | 2014-10-01 | old age, pain, screening | Journal of the American Geriatrics Society |
| Pain in patients with COPD: a systematic review and meta-analysis. | van Dam van Isselt EF, Groenewegen-Sipkema KH, Spruit-van Eijk M, Chavannes NH, de Waal MW, Janssen DJ, Achterberg WP | 2014-09-26 | PAIN MANAGEMENT, PRIMARY CARE, RESPIRATORY MEDICINE (see Thoracic Medicine) | BMJ open |
| NT-proBNP, blood pressure, and cognitive decline in the oldest old: The Leiden 85-plus Study. | van Vliet P, Sabayan B, Wijsman LW, Poortvliet RK, Mooijaart SP, de Ruijter W, Gussekloo J, de Craen AJ, Westendorp RG | 2014-09-23 | Neurology | |
| Efficacy of daily 800 IU vitamin D supplementation in reaching vitamin D sufficiency in nursing home residents: cross-sectional patient file study. | Veleva BI, Chel VG, Achterberg WP | 2014-09-19 | BMC geriatrics | |
| Global brain atrophy but not hippocampal atrophy is related to type 2 diabetes. | Wisse LE, de Bresser J, Geerlings MI, Reijmer YD, Portegies ML, Brundel M, Kappelle LJ, van der Graaf Y, Biessels GJ | 2014-09-15 | Atrophy, Brain, Hippocampus, MRI, Type 2 diabetes | Journal of the neurological sciences |
| Effectiveness of integrated disease management for primary care chronic obstructive pulmonary disease patients: results of cluster randomised trial. | Kruis AL, Boland MR, Assendelft WJ, Gussekloo J, Tsiachristas A, Stijnen T, Blom C, Sont JK, Rutten-van Mölken MP, Chavannes NH | 2014-09-10 | BMJ (Clinical research ed.) | |
| Symptoms and treatment when death is expected in dementia patients in long-term care facilities. | Klapwijk MS, Caljouw MA, van Soest-Poortvliet MC, van der Steen JT, Achterberg WP | 2014-09-02 | BMC geriatrics | |
| Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance. | Ramos YF, Metrustry S, Arden N, Bay-Jensen AC, Beekman M, de Craen AJ, Cupples LA, Esko T, Evangelou E, Felson DT, Hart DJ, Ioannidis JP, Karsdal M, Kloppenburg M, Lafeber F, Metspalu A, Panoutsopoulou K, Slagboom PE, Spector TD, van Spil EW, Uitterlinden AG, Zhu Y, Valdes AM, van Meurs JB, Meulenbelt I | 2014-09-01 | Genetic epidemiology, Genome-wide, Osteoarthritis | Journal of medical genetics |
| Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448 participants. | Broer L, Raschenberger J, Deelen J, Mangino M, Codd V, Pietiläinen KH, Albrecht E, Amin N, Beekman M, de Craen AJ, Gieger C, Haun M, Henneman P, Herder C, Hovatta I, Laser A, Kedenko L, Koenig W, Kollerits B, Moilanen E, Oostra BA, Paulweber B, Quaye L, Rissanen A, Roden M, Surakka I, Valdes AM, Vuolteenaho K, Thorand B, van Dijk KW, Kaprio J, Spector TD, Slagboom PE, Samani NJ, Kronenberg F, van Duijn CM, Ladwig KH | 2014-09-01 | European journal of epidemiology | |
| Thyroid antibody status, subclinical hypothyroidism, and the risk of coronary heart disease: an individual participant data analysis. | Collet TH, Bauer DC, Cappola AR, Asvold BO, Weiler S, Vittinghoff E, Gussekloo J, Bremner A, den Elzen WP, Maciel RM, Vanderpump MP, Cornuz J, Dörr M, Wallaschofski H, Newman AB, Sgarbi JA, Razvi S, Völzke H, Walsh JP, Aujesky D, Rodondi N | 2014-09-01 | The Journal of clinical endocrinology and metabolism | |
| The importance of pain management in older people with dementia. | Corbett A, Husebo BS, Achterberg WP, Aarsland D, Erdal A, Flo E | 2014-09-01 | analgesia, care, dementia, pain, treatment | British medical bulletin |
| Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age. | Deelen J, Beekman M, Uh HW, Broer L, Ayers KL, Tan Q, Kamatani Y, Bennet AM, Tamm R, Trompet S, Guðbjartsson DF, Flachsbart F, Rose G, Viktorin A, Fischer K, Nygaard M, Cordell HJ, Crocco P, van den Akker EB, Böhringer S, Helmer Q, Nelson CP, Saunders GI, Alver M, Andersen-Ranberg K, Breen ME, van der Breggen R, Caliebe A, Capri M, Cevenini E, Collerton JC, Dato S, Davies K, Ford I, Gampe J, Garagnani P, de Geus EJ, Harrow J, van Heemst D, Heijmans BT, Heinsen FA, Hottenga JJ, Hofman A, Jeune B, Jonsson PV, Lathrop M, Lechner D, Martin-Ruiz C, Mcnerlan SE, Mihailov E, Montesanto A, Mooijaart SP, Murphy A, Nohr EA, Paternoster L, Postmus I, Rivadeneira F, Ross OA, Salvioli S, Sattar N, Schreiber S, Stefánsson H, Stott DJ, Tiemeier H, Uitterlinden AG, Westendorp RG, Willemsen G, Samani NJ, Galan P, Sørensen TI, Boomsma DI, Jukema JW, Rea IM, Passarino G, de Craen AJ, Christensen K, Nebel A, Stefánsson K, Metspalu A, Magnusson P, Blanché H, Christiansen L, Kirkwood TB, van Duijn CM, Franceschi C, Houwing-Duistermaat JJ, Slagboom PE | 2014-08-15 | Human molecular genetics | |
| Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and type 2 diabetes susceptibility. | Guigas B, de Leeuw van Weenen JE, van Leeuwen N, Simonis-Bik AM, van Haeften TW, Nijpels G, Houwing-Duistermaat JJ, Beekman M, Deelen J, Havekes LM, Penninx BW, Vogelzangs N, van 't Riet E, Dehghan A, Hofman A, Witteman JC, Uitterlinden AG, Grarup N, Jørgensen T, Witte DR, Lauritzen T, Hansen T, Pedersen O, Hottenga J, Romijn JA, Diamant M, Kramer MH, Heine RJ, Willemsen G, Dekker JM, Eekhoff EM, Pijl H, de Geus EJ, Slagboom PE, 't Hart LM | 2014-08-01 | Diabetic medicine : a journal of the British Diabetic Association | |
| Choosing relevant endpoints for older breast cancer patients in clinical trials: an overview of all current clinical trials on breast cancer treatment. | de Glas NA, Hamaker ME, Kiderlen M, de Craen AJ, Mooijaart SP, van de Velde CJ, van Munster BC, Portielje JE, Liefers GJ, Bastiaannet E | 2014-08-01 | Breast cancer research and treatment | |
| Thyroid status and renal function in older persons in the general population. | Meuwese CL, Gussekloo J, de Craen AJ, Dekker FW, den Elzen WP | 2014-08-01 | The Journal of clinical endocrinology and metabolism | |
| N-terminal pro-brain natriuretic peptide and cognitive decline in older adults at high cardiovascular risk. | Wijsman LW, Sabayan B, van Vliet P, Trompet S, de Ruijter W, Poortvliet RK, van Peet PG, Gussekloo J, Jukema JW, Stott DJ, Sattar N, Ford I, Westendorp RG, de Craen AJ, Mooijaart SP | 2014-08-01 | Annals of neurology | |
| Response to David Nace and Paul Drinka. | Caljouw MA, van den Hout WB, Putter H, Achterberg WP, Cools HJ, Gussekloo J | 2014-08-01 | Journal of the American Geriatrics Society | |
| Scarcity of atrial fibrillation in a traditional African population: a community-based study. | Koopman JJ, van Bodegom D, Westendorp RG, Jukema JW | 2014-07-18 | BMC cardiovascular disorders | |
| In search for genetic determinants of clinically meaningful differential cardiovascular event reduction by pravastatin in the PHArmacogenetic study of Statins in the Elderly at risk (PHASE)/PROSPER study. | Postmus I, Johnson PC, Trompet S, de Craen AJ, Slagboom PE, Devlin JJ, Shiffman D, Sacks FM, Kearney PM, Stott DJ, Buckley BM, Sattar N, Ford I, Westendorp RG, Jukema JW | 2014-07-01 | Cardiovascular diseases, GWAS, Pharmacogenetics, Statins | Atherosclerosis |
| A metabolomic profile is associated with the risk of incident coronary heart disease. | Vaarhorst AA, Verhoeven A, Weller CM, Böhringer S, Göraler S, Meissner A, Deelder AM, Henneman P, Gorgels AP, van den Brandt PA, Schouten LJ, van Greevenbroek MM, Merry AH, Verschuren WM, van den Maagdenberg AM, van Dijk KW, Isaacs A, Boomsma D, Oostra BA, van Duijn CM, Jukema JW, Boer JM, Feskens E, Heijmans BT, Slagboom PE | 2014-07-01 | American heart journal | |
| Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk. | Walsh KM, Codd V, Smirnov IV, Rice T, Decker PA, Hansen HM, Kollmeyer T, Kosel ML, Molinaro AM, McCoy LS, Bracci PM, Cabriga BS, Pekmezci M, Zheng S, Wiemels JL, Pico AR, Tihan T, Berger MS, Chang SM, Prados MD, Lachance DH, O'Neill BP, Sicotte H, Eckel-Passow JE, van der Harst P, Wiencke JK, Samani NJ, Jenkins RB, Wrensch MR | 2014-07-01 | Nature genetics | |
| Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers. | Deelen J, Beekman M, Codd V, Trompet S, Broer L, Hägg S, Fischer K, Thijssen PE, Suchiman HE, Postmus I, Uitterlinden AG, Hofman A, de Craen AJ, Metspalu A, Pedersen NL, van Duijn CM, Jukema JW, Houwing-Duistermaat JJ, Samani NJ, Slagboom PE | 2014-06-01 | Leukocyte telomere length, familial longevity, genetics, human, immune-related markers, prospective mortality | International journal of epidemiology |
| Low mitochondrial DNA content associates with familial longevity: the Leiden Longevity Study. | van Leeuwen N, Beekman M, Deelen J, van den Akker EB, de Craen AJ, Slagboom PE, 't Hart LM | 2014-06-01 | Age (Dordrecht, Netherlands) | |
| MicroRNA-663 induction upon oxidative stress in cultured human fibroblasts depends on the chronological age of the donor. | Waaijer ME, Wieser M, Grillari-Voglauer R, van Heemst D, Grillari J, Maier AB | 2014-06-01 | Biogerontology | |
| Safety concerns for caesarean section. | van Roosmalen J, van den Akker T | 2014-06-01 | BJOG : an international journal of obstetrics and gynaecology | |
| Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation. | Lane AA, Chapuy B, Lin CY, Tivey T, Li H, Townsend EC, van Bodegom D, Day TA, Wu SC, Liu H, Yoda A, Alexe G, Schinzel AC, Sullivan TJ, Malinge S, Taylor JE, Stegmaier K, Jaffe JD, Bustin M, te Kronnie G, Izraeli S, Harris MH, Stevenson KE, Neuberg D, Silverman LB, Sallan SE, Bradner JE, Hahn WC, Crispino JD, Pellman D, Weinstock DM | 2014-06-01 | Nature genetics | |
| Determinants of epidemiologic transition in rural Africa: the role of socioeconomic status and drinking water source. | Engelaer FM, Koopman JJ, van Bodegom D, Eriksson UK, Westendorp RG | 2014-06-01 | Drinking water, Epidemiologic transition, Fertility, Ghana, Mortality, Socioeconomic status | Transactions of the Royal Society of Tropical Medicine and Hygiene |
| Genetic variation in VTCN1 (B7-H4) is associated with course of disease in juvenile idiopathic arthritis. | Albers HM, Reinards TH, Brinkman DM, Kamphuis SS, van Rossum MA, Hoppenreijs EP, Girschick HJ, Wouters C, Saurenmann RK, Bakker E, Verduijn W, Slagboom P, Huizinga TW, Toes RE, Houwing-Duistermaat JJ, ten Cate R, Schilham MW | 2014-06-01 | Arthritis, Disease Activity, Gene Polymorphism, Juvenile Idiopathic Arthritis, T Cells | Annals of the rheumatic diseases |
| Letter regarding the Paper by Pearce et al. Entitled ‘2013 ETA Guideline: Management of Subclinical Hypothyroidism’. | Mooijaart SP | 2014-06-01 | European thyroid journal | |
| Completeness of medication reviews provided by community pharmacists. | Kwint HF, Faber A, Gussekloo J, Bouvy ML | 2014-06-01 | community pharmacists, drug-related problems, expert reviewers, medication review | Journal of clinical pharmacy and therapeutics |
| Plasma NT-proBNP as predictor of change in functional status, cardiovascular morbidity and mortality in the oldest old: the Leiden 85-plus study. | van Peet PG, de Craen AJ, Gussekloo J, de Ruijter W | 2014-06-01 | Age (Dordrecht, Netherlands) | |
| The Dilemma of Treating Subclinical Hypothyroidism: Risk that Current Guidelines Do More Harm than Good. | Stott DJ, Bauer DC, Ford I, Kearney P, Gussekloo J, Quinn TJ, Rodondi N, Smit J, Westerdorp R | 2014-06-01 | European thyroid journal | |
| Natural course of care dependency in residents of long-term care facilities: prospective follow-up study. | Caljouw MA, Cools HJ, Gussekloo J | 2014-05-22 | BMC geriatrics | |
| Health status measured by the Clinical COPD Questionnaire (CCQ) improves following post-acute pulmonary rehabilitation in patients with advanced COPD: a prospective observational study. | van Dam van Isselt EF, Spruit M, Groenewegen-Sipkema KH, Chavannes NH, Achterberg WP | 2014-05-20 | NPJ primary care respiratory medicine | |
| Epigenetic variation in monozygotic twins: a genome-wide analysis of DNA methylation in buccal cells. | van Dongen J, Ehli EA, Slieker RC, Bartels M, Weber ZM, Davies GE, Slagboom PE, Heijmans BT, Boomsma DI | 2014-05-05 | Genes | |
| Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. | Huang J, Huffman JE, Yamakuchi M, Trompet S, Asselbergs FW, Sabater-Lleal M, Trégouët DA, Chen WM, Smith NL, Kleber ME, Shin SY, Becker DM, Tang W, Dehghan A, Johnson AD, Truong V, Folkersen L, Yang Q, Oudot-Mellkah T, Buckley BM, Moore JH, Williams FM, Campbell H, Silbernagel G, Vitart V, Rudan I, Tofler GH, Navis GJ, Destefano A, Wright AF, Chen MH, de Craen AJ, Worrall BB, Rudnicka AR, Rumley A, Bookman EB, Psaty BM, Chen F, Keene KL, Franco OH, Böhm BO, Uitterlinden AG, Carter AM, Jukema JW, Sattar N, Bis JC, Ikram MA, Sale MM, McKnight B, Fornage M, Ford I, Taylor K, Slagboom PE, McArdle WL, Hsu FC, Franco-Cereceda A, Goodall AH, Yanek LR, Furie KL, Cushman M, Hofman A, Witteman JC, Folsom AR, Basu S, Matijevic N, van Gilst WH, Wilson JF, Westendorp RG, Kathiresan S, Reilly MP, Tracy RP, Polasek O, Winkelmann BR, Grant PJ, Hillege HL, Cambien F, Stott DJ, Lowe GD, Spector TD, Meigs JB, Marz W, Eriksson P, Becker LC, Morange PE, Soranzo N, Williams SM, Hayward C, van der Harst P, Hamsten A, Lowenstein CJ, Strachan DP, O'Donnell CJ | 2014-05-01 | fibrinolysis, genome-wide association study, hemostasis, meta-analysis, tissue plasminogen activator | Arteriosclerosis, thrombosis, and vascular biology |
| Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31. | Styrkarsdottir U, Thorleifsson G, Helgadottir HT, Bomer N, Metrustry S, Bierma-Zeinstra S, Strijbosch AM, Evangelou E, Hart D, Beekman M, Jonasdottir A, Sigurdsson A, Eiriksson FF, Thorsteinsdottir M, Frigge ML, Kong A, Gudjonsson SA, Magnusson OT, Masson G, Hofman A, Arden NK, Ingvarsson T, Lohmander S, Kloppenburg M, Rivadeneira F, Nelissen RG, Spector T, Uitterlinden A, Slagboom PE, Thorsteinsdottir U, Jonsdottir I, Valdes AM, Meulenbelt I, van Meurs J, Jonsson H, Stefansson K | 2014-05-01 | Nature genetics | |
| Geriatric rehabilitation for patients with advanced chronic obstructive pulmonary disease: a naturalistic prospective cohort study on feasibility and course of health status. | van Dam van Isselt EF, Spruit M, Groenewegen-Sipkema KH, Chavannes NH, Achterberg WP | 2014-05-01 | Geriatric rehabilitation, advanced COPD, palliative care, pulmonary rehabilitation, skilled nursing facility | Chronic respiratory disease |
| Meta-analysis on blood transcriptomic studies identifies consistently coexpressed protein-protein interaction modules as robust markers of human aging. | van den Akker EB, Passtoors WM, Jansen R, van Zwet EW, Goeman JJ, Hulsman M, Emilsson V, Perola M, Willemsen G, Penninx BW, Heijmans BT, Maier AB, Boomsma DI, Kok JN, Slagboom PE, Reinders MJ, Beekman M | 2014-04-01 | aging, blood transcriptomics, meta-analysis, network-based analysis, protein-protein interactions | Aging cell |
| Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies. | Rodriguez-Fontenla C, Calaza M, Evangelou E, Valdes AM, Arden N, Blanco FJ, Carr A, Chapman K, Deloukas P, Doherty M, Esko T, Garcés Aletá CM, Gomez-Reino Carnota JJ, Helgadottir H, Hofman A, Jonsdottir I, Kerkhof HJ, Kloppenburg M, McCaskie A, Ntzani EE, Ollier WE, Oreiro N, Panoutsopoulou K, Ralston SH, Ramos YF, Riancho JA, Rivadeneira F, Slagboom PE, Styrkarsdottir U, Thorsteinsdottir U, Thorleifsson G, Tsezou A, Uitterlinden AG, Wallis GA, Wilkinson JM, Zhai G, Zhu Y, Felson DT, Ioannidis JP, Loughlin J, Metspalu A, Meulenbelt I, Stefansson K, van Meurs JB, Zeggini E, Spector TD, Gonzalez A | 2014-04-01 | Arthritis & rheumatology (Hoboken, N.J.) | |
| Health status and 6 years survival of 552 90+ Italian sib-ships recruited within the EU Project GEHA (GEnetics of Healthy Ageing). | Cevenini E, Cotichini R, Stazi MA, Toccaceli V, Palmas MG, Capri M, De Rango F, Dato S, Passarino G, Jeune B, Franceschi C | 2014-04-01 | Age (Dordrecht, Netherlands) | |
| Relation between caffeine and behavioral symptoms in elderly patients with dementia: an observational study. | Kromhout MA, Jongerling J, Achterberg WP | 2014-04-01 | The journal of nutrition, health & aging | |
| Association study of the estrogen receptor I gene (ESR1) in anorexia nervosa and eating disorders: no replication found. | Slof-Op 't Landt MC, van Furth EF, Meulenbelt I, Bartels M, Hottenga JJ, Slagboom PE, Boomsma DI | 2014-03-01 | ESR1, anorexia nervosa, eating disorders, estrogen, genetic association | The International journal of eating disorders |
| Seasonal variation in child and old-age mortality in rural Ghana. | Engelaer FM, van Bodegom D, Mangione JN, Eriksson UK, Westendorp RG | 2014-03-01 | Epidemiologic transition, Mortality, Old-age, Seasonal variation, Tropical countries | Transactions of the Royal Society of Tropical Medicine and Hygiene |
| Renal function in familial longevity: the Leiden Longevity Study. | de Goeij MC, Halbesma N, Dekker FW, Wijsman CA, van Heemst D, Maier AB, Mooijaart SP, Slagboom PE, Westendorp RG, de Craen AJ | 2014-03-01 | Aging, Cardiovascular disease, Longevity, Renal function, Sex | Experimental gerontology |
| Fear of falling after hip fracture in vulnerable older persons rehabilitating in a skilled nursing facility. | Visschedijk JH, Caljouw MA, van Balen R, Hertogh CM, Achterberg WP | 2014-03-01 | Journal of rehabilitation medicine | |
| A targeted mutational landscape of angioimmunoblastic T-cell lymphoma. | Odejide O, Weigert O, Lane AA, Toscano D, Lunning MA, Kopp N, Kim S, van Bodegom D, Bolla S, Schatz JH, Teruya-Feldstein J, Hochberg E, Louissaint A, Dorfman D, Stevenson K, Rodig SJ, Piccaluga PP, Jacobsen E, Pileri SA, Harris NL, Ferrero S, Inghirami G, Horwitz SM, Weinstock DM | 2014-02-27 | Blood | |
| Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval. | Avery CL, Sitlani CM, Arking DE, Arnett DK, Bis JC, Boerwinkle E, Buckley BM, Ida Chen YD, de Craen AJ, Eijgelsheim M, Enquobahrie D, Evans DS, Ford I, Garcia ME, Gudnason V, Harris TB, Heckbert SR, Hochner H, Hofman A, Hsueh WC, Isaacs A, Jukema JW, Knekt P, Kors JA, Krijthe BP, Kristiansson K, Laaksonen M, Liu Y, Li X, Macfarlane PW, Newton-Cheh C, Nieminen MS, Oostra BA, Peloso GM, Porthan K, Rice K, Rivadeneira FF, Rotter JI, Salomaa V, Sattar N, Siscovick DS, Slagboom PE, Smith AV, Sotoodehnia N, Stott DJ, Stricker BH, Stürmer T, Trompet S, Uitterlinden AG, van Duijn C, Westendorp RG, Witteman JC, Whitsel EA, Psaty BM | 2014-02-01 | The pharmacogenomics journal | |
| Relationship between the functional exon 3 deleted growth hormone receptor polymorphism and symptomatic osteoarthritis in women. | Claessen KM, Kloppenburg M, Kroon HM, Bijsterbosch J, Pereira AM, Romijn JA, van der Straaten T, Nelissen RG, Hofman A, Uitterlinden AG, Duijnisveld BJ, Lakenberg N, Beekman M, van Meurs JB, Slagboom PE, Biermasz NR, Meulenbelt I | 2014-02-01 | Chondrocytes, Gene Polymorphism, Osteoarthritis | Annals of the rheumatic diseases |
| Microstructural brain tissue damage in metabolic syndrome. | Sala M, de Roos A, van den Berg A, Altmann-Schneider I, Slagboom PE, Westendorp RG, van Buchem MA, de Craen AJ, van der Grond J | 2014-02-01 | Diabetes care | |
| A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus. | Oei L, Hsu YH, Styrkarsdottir U, Eussen BH, de Klein A, Peters MJ, Halldorsson B, Liu CT, Alonso N, Kaptoge SK, Thorleifsson G, Hallmans G, Hocking LJ, Husted LB, Jameson KA, Kruk M, Lewis JR, Patel MS, Scollen S, Svensson O, Trompet S, van Schoor NM, Zhu K, Buckley BM, Cooper C, Ford I, Goltzman D, González-Macías J, Langdahl BL, Leslie WD, Lips P, Lorenc RS, Olmos JM, Pettersson-Kymmer U, Reid DM, Riancho JA, Slagboom PE, Garcia-Ibarbia C, Ingvarsson T, Johannsdottir H, Luben R, Medina-Gómez C, Arp P, Nandakumar K, Palsson ST, Sigurdsson G, van Meurs JB, Zhou Y, Hofman A, Jukema JW, Pols HA, Prince RL, Cupples LA, Marshall CR, Pinto D, Sato D, Scherer SW, Reeve J, Thorsteinsdottir U, Karasik D, Richards JB, Stefansson K, Uitterlinden AG, Ralston SH, Ioannidis JP, Kiel DP, Rivadeneira F, Estrada K | 2014-02-01 | Calcium and Bone, Copy-Number, Genetic Epidemiology, Genome-Wide, Osteoporosis | Journal of medical genetics |
| Feasibility of measuring physical activity using accelerometry in hospitalized and community-living older people with cognitive impairment. | van Loevezijn AA, Cameron ID, Kurrle SE, van Bodegom D | 2014-02-01 | Journal of the American Geriatrics Society | |
| Subclinical thyroid dysfunction and functional capacity among elderly. | Virgini VS, Wijsman LW, Rodondi N, Bauer DC, Kearney PM, Gussekloo J, den Elzen WP, Jukema JW, Westendorp RG, Ford I, Stott DJ, Mooijaart SP | 2014-02-01 | Thyroid : official journal of the American Thyroid Association | |
| Disability transitions in the oldest old in the general population. The Leiden 85-plus study. | van Houwelingen AH, Cameron ID, Gussekloo J, Putter H, Kurrle S, de Craen AJ, Maier AB, den Elzen WP, Blom JW | 2014-02-01 | Age (Dordrecht, Netherlands) | |
| Quality of life in community-dwelling older persons with apathy. | Groeneweg-Koolhoven I, de Waal MW, van der Weele GM, Gussekloo J, van der Mast RC | 2014-02-01 | Apathy, cognition, elderly, general population, quality of life | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry |
| Homocysteine levels and treatment effect in the PROspective Study of Pravastatin in the Elderly at Risk. | Drewes YM, Poortvliet RK, Blom JW, de Ruijter W, Westendorp RG, Stott DJ, Blom HJ, Ford I, Sattar N, Wouter Jukema J, Assendelft WJ, de Craen AJ, Gussekloo J | 2014-02-01 | cardiovascular risk, homocysteine, older persons, prevention, statins | Journal of the American Geriatrics Society |
| Low computed tomography coronary artery calcium scores in familial longevity: the Leiden Longevity Study. | Kroft LJ, van der Bijl N, van der Grond J, Altmann-Schneider I, Slagboom PE, Westendorp RG, de Roos A, de Craen AJ | 2014-01-01 | Age (Dordrecht, Netherlands) | |
| Genes involved in the osteoarthritis process identified through genome wide expression analysis in articular cartilage; the RAAK study. | Ramos YF, den Hollander W, Bovée JV, Bomer N, van der Breggen R, Lakenberg N, Keurentjes JC, Goeman JJ, Slagboom PE, Nelissen RG, Bos SD, Meulenbelt I | 2014-01-01 | PloS one | |
| No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects. | Baumert J, Huang J, McKnight B, Sabater-Lleal M, Steri M, Chu AY, Trompet S, Lopez LM, Fornage M, Teumer A, Tang W, Rudnicka AR, Mälarstig A, Hottenga JJ, Kavousi M, Lahti J, Tanaka T, Hayward C, Huffman JE, Morange PE, Rose LM, Basu S, Rumley A, Stott DJ, Buckley BM, de Craen AJ, Sanna S, Masala M, Biffar R, Homuth G, Silveira A, Sennblad B, Goel A, Watkins H, Müller-Nurasyid M, Rückerl R, Taylor K, Chen MH, de Geus EJ, Hofman A, Witteman JC, de Maat MP, Palotie A, Davies G, Siscovick DS, Kolcic I, Wild SH, Song J, McArdle WL, Ford I, Sattar N, Schlessinger D, Grotevendt A, Franzosi MG, Illig T, Waldenberger M, Lumley T, Tofler GH, Willemsen G, Uitterlinden AG, Rivadeneira F, Räikkönen K, Chasman DI, Folsom AR, Lowe GD, Westendorp RG, Slagboom PE, Cucca F, Wallaschofski H, Strawbridge RJ, Seedorf U, Koenig W, Bis JC, Mukamal KJ, van Dongen J, Widen E, Franco OH, Starr JM, Liu K, Ferrucci L, Polasek O, Wilson JF, Oudot-Mellakh T, Campbell H, Navarro P, Bandinelli S, Eriksson J, Boomsma DI, Dehghan A, Clarke R, Hamsten A, Boerwinkle E, Jukema JW, Naitza S, Ridker PM, Völzke H, Deary IJ, Reiner AP, Trégouët DA, O'Donnell CJ, Strachan DP, Peters A, Smith NL | 2014-01-01 | PloS one | |
| Acute stress-induced cortisol elevations mediate reward system activity during subconscious processing of sexual stimuli. | Oei NYL, Both S, van Heemst D, van der Grond J | 2014-01-01 | Backward masking, Cortisol, Functional Imaging, Nucleus Accumbens, Reward, Social stress | Psychoneuroendocrinology |
| Old age mortality and macroeconomic cycles. | Rolden HJ, van Bodegom D, van den Hout WB, Westendorp RG | 2014-01-01 | ECONOMICS, ELDERLY, MORTALITY, PUBLIC HEALTH | Journal of epidemiology and community health |
| Arts and ageing; life expectancy of historical artists in the Low Countries. | Mirzada F, Schimberg AS, Engelaer FM, Bijwaard GE, van Bodegom D, Westendorp RG, van Poppel FW | 2014-01-01 | PloS one | |
| TSLP signaling pathway map: a platform for analysis of TSLP-mediated signaling. | Zhong J, Sharma J, Raju R, Palapetta SM, Prasad TS, Huang TC, Yoda A, Tyner JW, van Bodegom D, Weinstock DM, Ziegler SF, Pandey A | 2014-01-01 | Database : the journal of biological databases and curation | |
| Changes in health care expenditure after the loss of a spouse: data on 6,487 older widows and widowers in the Netherlands. | Rolden HJ, van Bodegom D, Westendorp RG | 2014-01-01 | PloS one | |
| Association of liver enzymes and computed tomography markers of liver steatosis with familial longevity. | Sala M, Kroft LJ, Röell B, van der Grond J, Slagboom PE, Mooijaart SP, de Roos A, van Heemst D | 2014-01-01 | PloS one | |
| The heart-brain connection: a multidisciplinary approach targeting a missing link in the pathophysiology of vascular cognitive impairment. | van Buchem MA, Biessels GJ, Brunner la Rocca HP, de Craen AJ, van der Flier WM, Ikram MA, Kappelle LJ, Koudstaal PJ, Mooijaart SP, Niessen W, van Oostenbrugge R, de Roos A, van Rossum AC, Daemen MJ | 2014-01-01 | Atherosclerosis, heart, magnetic resonance imaging, vascular cognitive impairment | Journal of Alzheimer's disease : JAD |
| Level of satisfaction of older persons with their general practitioner and practice: role of complexity of health problems. | Poot AJ, den Elzen WP, Blom JW, Gussekloo J | 2014-01-01 | PloS one | |
| Cost-effectiveness of cranberry capsules to prevent urinary tract infection in long-term care facilities: economic evaluation with a randomized controlled trial. | van den Hout WB, Caljouw MA, Putter H, Cools HJ, Gussekloo J | 2014-01-01 | Journal of the American Geriatrics Society | |
| Comparison of quadriceps strength and handgrip strength in their association with health outcomes in older adults in primary care. | Chan OY, van Houwelingen AH, Gussekloo J, Blom JW, den Elzen WP | 2014-01-01 | Age (Dordrecht, Netherlands) | |
| Variability in vulnerability assessment of older people by individual general practitioners: a cross-sectional study. | Drewes YM, Blom JW, Assendelft WJ, Stijnen T, den Elzen WP, Gussekloo J | 2014-01-01 | PloS one | |
| [The complexity of medical care of frail older patients]. | Olde Rikkert MG, Gussekloo J | 2014-01-01 | Nederlands tijdschrift voor geneeskunde | |
| Multiple microbleeds are related to cerebral network disruptions in patients with early Alzheimer’s disease. | Heringa SM, Reijmer YD, Leemans A, Koek HL, Kappelle LJ, Biessels GJ | 2014-01-01 | Alzheimer's disease, cerebral amyloid angiopathy, cerebral small vessel disease, cognition, diffusion tensor imaging, magnetic resonance imaging, microbleeds, mild cognitive impairment, network | Journal of Alzheimer's disease : JAD |
| Effectiveness of cranberry capsules to prevent urinary tract infections in vulnerable older persons: a double-blind randomized placebo-controlled trial in long-term care facilities. | Caljouw MA, van den Hout WB, Putter H, Achterberg WP, Cools HJ, Gussekloo J | 2014-01-01 | Journal of the American Geriatrics Society | |
| Preserved white matter integrity is a marker of familial longevity. | Altmann-Schneider I, de Craen AJ, Veer IM, van den Berg-Huysmans AA, Slagboom PE, Westendorp RG, van Buchem MA, van der Grond J | 2013-12-01 | Annals of neurology | |
| Aging as accelerated accumulation of somatic variants: whole-genome sequencing of centenarian and middle-aged monozygotic twin pairs. | Ye K, Beekman M, Lameijer EW, Zhang Y, Moed MH, van den Akker EB, Deelen J, Houwing-Duistermaat JJ, Kremer D, Anvar SY, Laros JF, Jones D, Raine K, Blackburne B, Potluri S, Long Q, Guryev V, van der Breggen R, Westendorp RG, 't Hoen PA, den Dunnen J, van Ommen GJ, Willemsen G, Pitts SJ, Cox DR, Ning Z, Boomsma DI, Slagboom PE | 2013-12-01 | Twin research and human genetics : the official journal of the International Society for Twin Studies | |
| Diagnostic criteria for sarcopenia relate differently to insulin resistance. | Bijlsma AY, Meskers CG, van Heemst D, Westendorp RG, de Craen AJ, Maier AB | 2013-12-01 | Age (Dordrecht, Netherlands) | |
| Effects of a web-based intervention on physical activity and metabolism in older adults: randomized controlled trial. | Wijsman CA, Westendorp RG, Verhagen EA, Catt M, Slagboom PE, de Craen AJ, Broekhuizen K, van Mechelen W, van Heemst D, van der Ouderaa F, Mooijaart SP | 2013-11-06 | Internet, accelerometry, aging, metabolism, physical activity, self-monitoring | Journal of medical Internet research |
| p53 regulates a non-apoptotic death induced by ROS. | Montero J, Dutta C, van Bodegom D, Weinstock D, Letai A | 2013-11-01 | Cell death and differentiation | |
| How to classify the oldest old according to their health status: a study on 1160 subjects belonging to 552 90+ Italian sib-ships characterized by familial longevity recruited within the GEHA EU Project. | Cevenini E, Cotichini R, Stazi MA, Toccaceli V, Scurti M, Mari V, Berardelli M, Passarino G, Jeune B, Franceschi C | 2013-11-01 | Gender, Health status classification, Longevity, Mortality, Oldest old | Mechanisms of ageing and development |
| Integrated disease management interventions for patients with chronic obstructive pulmonary disease. | Kruis AL, Smidt N, Assendelft WJ, Gussekloo J, Boland MR, Rutten-van Mölken M, Chavannes NH | 2013-10-10 | The Cochrane database of systematic reviews | |
| Metabolic health in families enriched for longevity is associated with low prevalence of hand osteoarthritis and influences OA biomarker profiles. | Bos SD, Beekman M, Maier AB, Karsdal MA, Kwok WY, Bay-Jensen AC, Kloppenburg M, Slagboom PE, Meulenbelt I | 2013-10-01 | Epidemiology, Hand Osteoarthritis, Osteoarthritis | Annals of the rheumatic diseases |
| Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect. | Broer L, Codd V, Nyholt DR, Deelen J, Mangino M, Willemsen G, Albrecht E, Amin N, Beekman M, de Geus EJ, Henders A, Nelson CP, Steves CJ, Wright MJ, de Craen AJ, Isaacs A, Matthews M, Moayyeri A, Montgomery GW, Oostra BA, Vink JM, Spector TD, Slagboom PE, Martin NG, Samani NJ, van Duijn CM, Boomsma DI | 2013-10-01 | European journal of human genetics : EJHG | |
| The influence of clan structure on the genetic variation in a single Ghanaian village. | Sanchez-Faddeev H, Pijpe J, van der Hulle T, Meij HJ, van der Gaag KJ, Slagboom PE, Westendorp RG, de Knijff P | 2013-10-01 | European journal of human genetics : EJHG | |
| Familial resemblance for serum metabolite concentrations. | Draisma HH, Beekman M, Pool R, van Ommen GJ, Adamski J, Prehn C, Vaarhorst AA, de Craen AJ, Willemsen G, Slagboom PE, Boomsma DI | 2013-10-01 | Twin research and human genetics : the official journal of the International Society for Twin Studies | |
| Relationship of patient volume and service concentration with outcome in geriatric rehabilitation. | Holstege MS, Zekveld IG, Caljouw MA, Peerenboom PB, van Balen R, Gussekloo J, Achterberg WP | 2013-10-01 | Geriatric rehabilitation, discharge destination, length of stay, postacute care | Journal of the American Medical Directors Association |
| The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway. | 't Hart LM, Fritsche A, Nijpels G, van Leeuwen N, Donnelly LA, Dekker JM, Alssema M, Fadista J, Carlotti F, Gjesing AP, Palmer CN, van Haeften TW, Herzberg-Schäfer SA, Simonis-Bik AM, Houwing-Duistermaat JJ, Helmer Q, Deelen J, Guigas B, Hansen T, Machicao F, Willemsen G, Heine RJ, Kramer MH, Holst JJ, de Koning EJ, Häring HU, Pedersen O, Groop L, de Geus EJ, Slagboom PE, Boomsma DI, Eekhoff EM, Pearson ER, Diamant M | 2013-09-01 | Diabetes | |
| Duration of breastfeeding and gender are associated with methylation of the LEPTIN gene in very young children. | Obermann-Borst SA, Eilers PH, Tobi EW, de Jong FH, Slagboom PE, Heijmans BT, Steegers-Theunissen RP | 2013-09-01 | Pediatric research | |
| Medication adherence and knowledge of older patients with and without multidose drug dispensing. | Kwint HF, Stolk G, Faber A, Gussekloo J, Bouvy ML | 2013-09-01 | adherence, adherence aids, medication knowledge, multidose drug dispensing, older people | Age and ageing |
| Natural course of cutaneous warts among primary schoolchildren: a prospective cohort study. | Bruggink SC, Eekhof JA, Egberts PF, van Blijswijk SC, Assendelft WJ, Gussekloo J | 2013-09-01 | cutaneous warts, natural course, primary care, schoolchildren | Annals of family medicine |
| Interventions targeting pain or behaviour in dementia: a systematic review. | Pieper MJ, van Dalen-Kok AH, Francke AL, van der Steen JT, Scherder EJ, Husebø BS, Achterberg WP | 2013-09-01 | Behavior, Dementia, Neuropsychiatric symptoms, Non-pharmacological and pharmacological interventions, Pain | Ageing research reviews |
| Feedback on end-of-life care in dementia: the study protocol of the FOLlow-up project. | Boogaard JA, van Soest-Poortvliet MC, Anema JR, Achterberg WP, Hertogh CM, de Vet HC, van der Steen JT | 2013-08-07 | BMC palliative care | |
| Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array. | Slieker RC, Bos SD, Goeman JJ, Bovée JV, Talens RP, van der Breggen R, Suchiman HE, Lameijer EW, Putter H, van den Akker EB, Zhang Y, Jukema JW, Slagboom PE, Meulenbelt I, Heijmans BT | 2013-08-06 | Epigenetics & chromatin | |
| The Val66Met polymorphism of the BDNF gene in anorexia nervosa: new data and a meta-analysis. | Brandys MK, Kas MJ, van Elburg AA, Ophoff R, Slof-Op't Landt MC, Middeldorp CM, Boomsma DI, van Furth EF, Slagboom PE, Adan RA | 2013-08-01 | The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry | |
| Genome-wide linkage scan in affected sibling pairs identifies novel susceptibility region for venous thromboembolism: Genetics In Familial Thrombosis study. | de Visser MC, van Minkelen R, van Marion V, den Heijer M, Eikenboom J, Vos HL, Slagboom PE, Houwing-Duistermaat JJ, Rosendaal FR, Bertina RM | 2013-08-01 | genetic linkage, siblings, thromboembolism, thrombophilia, thrombosis | Journal of thrombosis and haemostasis : JTH |
| Pro-inflammatory capacity of classically activated monocytes relates positively to muscle mass and strength. | Beenakker KG, Westendorp RG, de Craen AJ, Slagboom PE, van Heemst D, Maier AB | 2013-08-01 | cytokines, gender differences, handgrip strength, inflammation, innate immunity, macrophage, monocyte, skeletal muscle | Aging cell |
| Thyroid hormone signaling and homeostasis during aging. | Bowers J, Terrien J, Clerget-Froidevaux MS, Gothié JD, Rozing MP, Westendorp RG, van Heemst D, Demeneix BA | 2013-08-01 | Endocrine reviews | |
| Better health, longer lives. | Engelaer FM, van Bodegom D, Westendorp RG | 2013-08-01 | Ageing, Health policy, Healthy life expectancy, Life expectancy | Maturitas |
| Prognostic value of cardiovascular disease status: the Leiden 85-plus study. | van Peet PG, Drewes YM, de Craen AJ, Westendorp RG, Gussekloo J, de Ruijter W | 2013-08-01 | Age (Dordrecht, Netherlands) | |
| Association of visit-to-visit variability in blood pressure with cognitive function in old age: prospective cohort study. | Sabayan B, Wijsman LW, Foster-Dingley JC, Stott DJ, Ford I, Buckley BM, Sattar N, Jukema JW, van Osch MJ, van der Grond J, van Buchem MA, Westendorp RG, de Craen AJ, Mooijaart SP | 2013-07-29 | BMJ (Clinical research ed.) | |
| Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects. | Williams FM, Bansal AT, van Meurs JB, Bell JT, Meulenbelt I, Suri P, Rivadeneira F, Sambrook PN, Hofman A, Bierma-Zeinstra S, Menni C, Kloppenburg M, Slagboom PE, Hunter DJ, MacGregor AJ, Uitterlinden AG, Spector TD | 2013-07-01 | Gene Polymorphism, Low Back Pain, Magnetic Resonance Imaging | Annals of the rheumatic diseases |
| The DOT1L rs12982744 polymorphism is associated with osteoarthritis of the hip with genome-wide statistical significance in males. | Evangelou E, Valdes AM, Castano-Betancourt MC, Doherty M, Doherty S, Esko T, Ingvarsson T, Ioannidis JP, Kloppenburg M, Metspalu A, Ntzani EE, Panoutsopoulou K, Slagboom PE, Southam L, Spector TD, Styrkarsdottir U, Stefanson K, Uitterlinden AG, Wheeler M, Zeggini E, Meulenbelt I, van Meurs JB | 2013-07-01 | Epidemiology, Gene Polymorphism, Osteoarthritis | Annals of the rheumatic diseases |
| Gerontology and geriatrics in Dutch medical education. | Tersmette W, van Bodegom D, van Heemst D, Stott D, Westendorp R | 2013-07-01 | The Netherlands journal of medicine | |
| The shared allelic architecture of adiponectin levels and coronary artery disease. | Dastani Z, Johnson T, Kronenberg F, Nelson CP, Assimes TL, März W, Richards JB | 2013-07-01 | Atherosclerosis | |
| Circulating interleukin-6 concentration and cognitive decline in old age: the PROSPER study. | Mooijaart SP, Sattar N, Trompet S, Lucke J, Stott DJ, Ford I, Jukema JW, Westendorp RG, de Craen AJ | 2013-07-01 | Journal of internal medicine | |
| Clinically diagnosed infections predict disability in activities of daily living among the oldest-old in the general population: the Leiden 85-plus Study. | Caljouw MA, Kruijdenberg SJ, de Craen AJ, Cools HJ, den Elzen WP, Gussekloo J | 2013-07-01 | ADL disability, general population, infections, older people, oldest-old | Age and ageing |
| HPV type in plantar warts influences natural course and treatment response: secondary analysis of a randomised controlled trial. | Bruggink SC, Gussekloo J, de Koning MN, Feltkamp MC, Bavinck JN, Quint WG, Assendelft WJ, Eekhof JA | 2013-07-01 | Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology | |
| Framingham stroke risk score and cognitive impairment for predicting first-time stroke in the oldest old. | Sabayan B, Gussekloo J, de Ruijter W, Westendorp RG, de Craen AJ | 2013-07-01 | cognitive impairment, oldest old, stroke | Stroke |
| Reliability and minimal detectable change of physical performance measures in individuals with pre-manifest and manifest Huntington disease. | Quinn L, Khalil H, Dawes H, Fritz NE, Kegelmeyer D, Kloos AD, Gillard JW, Busse M | 2013-07-01 | Physical therapy | |
| Prediction of mortality and functional decline by changes in eGFR in the very elderly: the Leiden 85-plus study. | Van Pottelbergh G, Den Elzen WP, Degryse J, Gussekloo J | 2013-06-18 | BMC geriatrics | |
| Relative validity of the food frequency questionnaire used to assess dietary intake in the Leiden Longevity Study. | Streppel MT, de Vries JH, Meijboom S, Beekman M, de Craen AJ, Slagboom PE, Feskens EJ | 2013-06-07 | Nutrition journal | |
| Visual cerebral microbleed detection on 7T MR imaging: reliability and effects of image processing. | de Bresser J, Brundel M, Conijn MM, van Dillen JJ, Geerlings MI, Viergever MA, Luijten PR, Biessels GJ | 2013-06-01 | AJNR. American journal of neuroradiology | |
| High prevalence of vitamin D deficiency and insufficiency in patients with manifest Huntington disease: An explorative study. | Chel VG, Ooms ME, van der Bent J, Veldkamp F, Roos RA, Achterberg WP, Lips P | 2013-06-01 | Huntington disease, fall risk, nursing home, vitamin D deficiency, vitamin D insufficiency | Dermato-endocrinology |
| Parasitic infections and immune function: effect of helminth infections in a malaria endemic area. | Boef AG, May L, van Bodegom D, van Lieshout L, Verweij JJ, Maier AB, Westendorp RG, Eriksson UK | 2013-05-01 | Immunobiology | |
| Low blood pressure predicts increased mortality in very old age even without heart failure: the Leiden 85-plus Study. | Poortvliet RK, Blom JW, de Craen AJ, Mooijaart SP, Westendorp RG, Assendelft WJ, Gussekloo J, de Ruijter W | 2013-05-01 | European journal of heart failure | |
| Resting heart rate and incident heart failure and cardiovascular mortality in older adults: role of inflammation and endothelial dysfunction: the PROSPER study. | Nanchen D, Stott DJ, Gussekloo J, Mooijaart SP, Westendorp RG, Jukema JW, Macfarlane PW, Cornuz J, Rodondi N, Buckley BM, Ford I, Sattar N, de Craen AJ | 2013-05-01 | European journal of heart failure | |
| Warts transmitted in families and schools: a prospective cohort. | Bruggink SC, Eekhof JA, Egberts PF, van Blijswijk SC, Assendelft WJ, Gussekloo J | 2013-05-01 | cohort study, human papillomavirus, incidence, schoolchildren, transmission, warts | Pediatrics |
| Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity. | Soerensen M, Dato S, Tan Q, Thinggaard M, Kleindorp R, Beekman M, Suchiman HE, Jacobsen R, McGue M, Stevnsner T, Bohr VA, de Craen AJ, Westendorp RG, Schreiber S, Slagboom PE, Nebel A, Vaupel JW, Christensen K, Christiansen L | 2013-04-01 | Age (Dordrecht, Netherlands) | |
| Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study. | Beekman M, Blanché H, Perola M, Hervonen A, Bezrukov V, Sikora E, Flachsbart F, Christiansen L, De Craen AJ, Kirkwood TB, Rea IM, Poulain M, Robine JM, Valensin S, Stazi MA, Passarino G, Deiana L, Gonos ES, Paternoster L, Sørensen TI, Tan Q, Helmer Q, van den Akker EB, Deelen J, Martella F, Cordell HJ, Ayers KL, Vaupel JW, Törnwall O, Johnson TE, Schreiber S, Lathrop M, Skytthe A, Westendorp RG, Christensen K, Gampe J, Nebel A, Houwing-Duistermaat JJ, Slagboom PE, Franceschi C | 2013-04-01 | Aging cell | |
| Association study of candidate genes for the progression of hand osteoarthritis. | Bijsterbosch J, Kloppenburg M, Reijnierse M, Rosendaal FR, Huizinga TW, Slagboom PE, Meulenbelt I | 2013-04-01 | Osteoarthritis and cartilage | |
| Identifying the genomic determinants of aging and longevity in human population studies: progress and challenges. | Deelen J, Beekman M, Capri M, Franceschi C, Slagboom PE | 2013-04-01 | BioEssays : news and reviews in molecular, cellular and developmental biology | |
| Identification of seven loci affecting mean telomere length and their association with disease. | Codd V, Nelson CP, Albrecht E, Mangino M, Deelen J, Buxton JL, Hottenga JJ, Fischer K, Esko T, Surakka I, Broer L, Nyholt DR, Mateo Leach I, Salo P, Hägg S, Matthews MK, Palmen J, Norata GD, O'Reilly PF, Saleheen D, Amin N, Balmforth AJ, Beekman M, de Boer RA, Böhringer S, Braund PS, Burton PR, de Craen AJ, Denniff M, Dong Y, Douroudis K, Dubinina E, Eriksson JG, Garlaschelli K, Guo D, Hartikainen AL, Henders AK, Houwing-Duistermaat JJ, Kananen L, Karssen LC, Kettunen J, Klopp N, Lagou V, van Leeuwen EM, Madden PA, Mägi R, Magnusson PK, Männistö S, McCarthy MI, Medland SE, Mihailov E, Montgomery GW, Oostra BA, Palotie A, Peters A, Pollard H, Pouta A, Prokopenko I, Ripatti S, Salomaa V, Suchiman HE, Valdes AM, Verweij N, Viñuela A, Wang X, Wichmann HE, Widen E, Willemsen G, Wright MJ, Xia K, Xiao X, van Veldhuisen DJ, Catapano AL, Tobin MD, Hall AS, Blakemore AI, van Gilst WH, Zhu H, Erdmann J, Reilly MP, Kathiresan S, Schunkert H, Talmud PJ, Pedersen NL, Perola M, Ouwehand W, Kaprio J, Martin NG, van Duijn CM, Hovatta I, Gieger C, Metspalu A, Boomsma DI, Jarvelin MR, Slagboom PE, Thompson JR, Spector TD, van der Harst P, Samani NJ | 2013-04-01 | Nature genetics | |
| Ambulant 24-h glucose rhythms mark calendar and biological age in apparently healthy individuals. | Wijsman CA, van Heemst D, Hoogeveen ES, Slagboom PE, Maier AB, de Craen AJ, van der Ouderaa F, Pijl H, Westendorp RG, Mooijaart SP | 2013-04-01 | Aging cell | |
| Changing prediction of mortality by systolic blood pressure with increasing age: the Rotterdam study. | Blom JW, de Ruijter W, Witteman JC, Assendelft WJ, Breteler MM, Hofman A, Gussekloo J | 2013-04-01 | Age (Dordrecht, Netherlands) | |
| RECODE: design and baseline results of a cluster randomized trial on cost-effectiveness of integrated COPD management in primary care. | Kruis AL, Boland MR, Schoonvelde CH, Assendelft WJ, Rutten-van Mölken MP, Gussekloo J, Tsiachristas A, Chavannes NH | 2013-03-23 | BMC pulmonary medicine | |
| N-glycomic biomarkers of biological aging and longevity: a link with inflammaging. | Dall'Olio F, Vanhooren V, Chen CC, Slagboom PE, Wuhrer M, Franceschi C | 2013-03-01 | Ageing research reviews | |
| Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region. | Peters MJ, Broer L, Willemen HL, Eiriksdottir G, Hocking LJ, Holliday KL, Horan MA, Meulenbelt I, Neogi T, Popham M, Schmidt CO, Soni A, Valdes AM, Amin N, Dennison EM, Eijkelkamp N, Harris TB, Hart DJ, Hofman A, Huygen FJ, Jameson KA, Jones GT, Launer LJ, Kerkhof HJ, de Kruijf M, McBeth J, Kloppenburg M, Ollier WE, Oostra B, Payton A, Rivadeneira F, Smith BH, Smith AV, Stolk L, Teumer A, Thomson W, Uitterlinden AG, Wang K, van Wingerden SH, Arden NK, Cooper C, Felson D, Gudnason V, Macfarlane GJ, Pendleton N, Slagboom PE, Spector TD, Völzke H, Kavelaars A, van Duijn CM, Williams FM, van Meurs JB | 2013-03-01 | Annals of the rheumatic diseases | |
| Serum insulin-like growth factor 1 and facial ageing: high levels associate with reduced skin wrinkling in a cross-sectional study. | Noordam R, Gunn DA, Tomlin CC, Maier AB, Griffiths T, Catt SD, Ogden S, Slagboom PE, Westendorp RG, Griffiths CE, van Heemst D, de Craen AJ | 2013-03-01 | The British journal of dermatology | |
| Plasma hepcidin levels and anemia in old age. The Leiden 85-Plus Study. | den Elzen WP, de Craen AJ, Wiegerinck ET, Westendorp RG, Swinkels DW, Gussekloo J | 2013-03-01 | Haematologica | |
| The diagnosis of depression and use of antidepressants in nursing home residents with and without dementia. | van Asch IF, Nuyen J, Veerbeek MA, Frijters DH, Achterberg WP, Pot AM | 2013-03-01 | International journal of geriatric psychiatry | |
| Selecting the best instruments to measure quality of end-of-life care and quality of dying in long term care. | van Soest-Poortvliet MC, van der Steen JT, Zimmerman S, Cohen LW, Reed D, Achterberg WP, Ribbe MW, de Vet HC | 2013-03-01 | Journal of the American Medical Directors Association | |
| Geriatric rehabilitation for patients with advanced COPD: programme characteristics and case studies. | van Dam van Isselt EF, Groenewegen-Sipkema KH, Spruit-van Eijk M, Chavannes NH, Achterberg WP | 2013-03-01 | International journal of palliative nursing | |
| Case 34-2012: Severe pain, bleeding, and shock during labor. | Koop K, van Roosmalen J, van den Akker T | 2013-02-21 | The New England journal of medicine | |
| Local health workers’ perceptions of substandard care in the management of obstetric hemorrhage in rural Malawi. | Beltman JJ, van den Akker T, Bwirire D, Korevaar A, Chidakwani R, van Lonkhuijzen L, van Roosmalen J | 2013-02-15 | BMC pregnancy and childbirth | |
| Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes. | Albrechtsen A, Grarup N, Li Y, Sparsø T, Tian G, Cao H, Jiang T, Kim SY, Korneliussen T, Li Q, Nie C, Wu R, Skotte L, Morris AP, Ladenvall C, Cauchi S, Stančáková A, Andersen G, Astrup A, Banasik K, Bennett AJ, Bolund L, Charpentier G, Chen Y, Dekker JM, Doney AS, Dorkhan M, Forsen T, Frayling TM, Groves CJ, Gui Y, Hallmans G, Hattersley AT, He K, Hitman GA, Holmkvist J, Huang S, Jiang H, Jin X, Justesen JM, Kristiansen K, Kuusisto J, Lajer M, Lantieri O, Li W, Liang H, Liao Q, Liu X, Ma T, Ma X, Manijak MP, Marre M, Mokrosiński J, Morris AD, Mu B, Nielsen AA, Nijpels G, Nilsson P, Palmer CN, Rayner NW, Renström F, Ribel-Madsen R, Robertson N, Rolandsson O, Rossing P, Schwartz TW, Slagboom PE, Sterner M, Tang M, Tarnow L, Tuomi T, van't Riet E, van Leeuwen N, Varga TV, Vestmar MA, Walker M, Wang B, Wang Y, Wu H, Xi F, Yengo L, Yu C, Zhang X, Zhang J, Zhang Q, Zhang W, Zheng H, Zhou Y, Altshuler D, 't Hart LM, Franks PW, Balkau B, Froguel P, McCarthy MI, Laakso M, Groop L, Christensen C, Brandslund I, Lauritzen T, Witte DR, Linneberg A, Jørgensen T, Hansen T, Wang J, Nielsen R, Pedersen O | 2013-02-01 | Diabetologia | |
| The Adult Netherlands Twin Register: twenty-five years of survey and biological data collection. | Willemsen G, Vink JM, Abdellaoui A, den Braber A, van Beek JH, Draisma HH, van Dongen J, van 't Ent D, Geels LM, van Lien R, Ligthart L, Kattenberg M, Mbarek H, de Moor MH, Neijts M, Pool R, Stroo N, Kluft C, Suchiman HE, Slagboom PE, de Geus EJ, Boomsma DI | 2013-02-01 | Twin research and human genetics : the official journal of the International Society for Twin Studies | |
| PCSK9 SNP rs11591147 is associated with low cholesterol levels but not with cognitive performance or noncardiovascular clinical events in an elderly population. | Postmus I, Trompet S, de Craen AJ, Buckley BM, Ford I, Stott DJ, Sattar N, Slagboom PE, Westendorp RG, Jukema JW | 2013-02-01 | Journal of lipid research | |
| Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways. | Deelen J, Uh HW, Monajemi R, van Heemst D, Thijssen PE, Böhringer S, van den Akker EB, de Craen AJ, Rivadeneira F, Uitterlinden AG, Westendorp RG, Goeman JJ, Slagboom PE, Houwing-Duistermaat JJ, Beekman M | 2013-02-01 | Age (Dordrecht, Netherlands) | |
| Facial appearance reflects human familial longevity and cardiovascular disease risk in healthy individuals. | Gunn DA, de Craen AJ, Dick JL, Tomlin CC, van Heemst D, Catt SD, Griffiths T, Ogden S, Maier AB, Murray PG, Griffiths CE, Slagboom PE, Westendorp RG | 2013-02-01 | The journals of gerontology. Series A, Biological sciences and medical sciences | |
| Gene expression analysis of mTOR pathway: association with human longevity. | Passtoors WM, Beekman M, Deelen J, van der Breggen R, Maier AB, Guigas B, Derhovanessian E, van Heemst D, de Craen AJ, Gunn DA, Pawelec G, Slagboom PE | 2013-02-01 | Aging cell | |
| High serum glucose levels are associated with a higher perceived age. | Noordam R, Gunn DA, Tomlin CC, Maier AB, Mooijaart SP, Slagboom PE, Westendorp RG, de Craen AJ, van Heemst D | 2013-02-01 | Age (Dordrecht, Netherlands) | |
| The relationship between the extent of collaboration of general practitioners and pharmacists and the implementation of recommendations arising from medication review: a systematic review. | Kwint HF, Bermingham L, Faber A, Gussekloo J, Bouvy ML | 2013-02-01 | Drugs & aging | |
| Lower susceptibility to cerebral small vessel disease in human familial longevity: the Leiden Longevity Study. | Altmann-Schneider I, van der Grond J, Slagboom PE, Westendorp RG, Maier AB, van Buchem MA, de Craen AJ | 2013-01-01 | Stroke | |
| Genetic variation at the TPH2 gene influences impulsivity in addition to eating disorders. | Slof-Op't Landt MC, Bartels M, Middeldorp CM, van Beijsterveldt CE, Slagboom PE, Boomsma DI, van Furth EF, Meulenbelt I | 2013-01-01 | Behavior genetics | |
| Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. | Lauc G, Huffman JE, Pučić M, Zgaga L, Adamczyk B, Mužinić A, Novokmet M, Polašek O, Gornik O, Krištić J, Keser T, Vitart V, Scheijen B, Uh HW, Molokhia M, Patrick AL, McKeigue P, Kolčić I, Lukić IK, Swann O, van Leeuwen FN, Ruhaak LR, Houwing-Duistermaat JJ, Slagboom PE, Beekman M, de Craen AJ, Deelder AM, Zeng Q, Wang W, Hastie ND, Gyllensten U, Wilson JF, Wuhrer M, Wright AF, Rudd PM, Hayward C, Aulchenko Y, Campbell H, Rudan I | 2013-01-01 | PLoS genetics | |
| Non-homologous end-joining pathway associated with occurrence of myocardial infarction: gene set analysis of genome-wide association study data. | Verschuren JJ, Trompet S, Deelen J, Stott DJ, Sattar N, Buckley BM, Ford I, Heijmans BT, Guchelaar HJ, Houwing-Duistermaat JJ, Slagboom PE, Jukema JW | 2013-01-01 | PloS one | |
| Pathway analysis using genome-wide association study data for coronary restenosis–a potential role for the PARVB gene. | Verschuren JJ, Trompet S, Sampietro ML, Heijmans BT, Koch W, Kastrati A, Houwing-Duistermaat JJ, Slagboom PE, Quax PH, Jukema JW | 2013-01-01 | PloS one | |
| A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. | Porcu E, Medici M, Pistis G, Volpato CB, Wilson SG, Cappola AR, Bos SD, Deelen J, den Heijer M, Freathy RM, Lahti J, Liu C, Lopez LM, Nolte IM, O'Connell JR, Tanaka T, Trompet S, Arnold A, Bandinelli S, Beekman M, Böhringer S, Brown SJ, Buckley BM, Camaschella C, de Craen AJ, Davies G, de Visser MC, Ford I, Forsen T, Frayling TM, Fugazzola L, Gögele M, Hattersley AT, Hermus AR, Hofman A, Houwing-Duistermaat JJ, Jensen RA, Kajantie E, Kloppenburg M, Lim EM, Masciullo C, Mariotti S, Minelli C, Mitchell BD, Nagaraja R, Netea-Maier RT, Palotie A, Persani L, Piras MG, Psaty BM, Räikkönen K, Richards JB, Rivadeneira F, Sala C, Sabra MM, Sattar N, Shields BM, Soranzo N, Starr JM, Stott DJ, Sweep FC, Usala G, van der Klauw MM, van Heemst D, van Mullem A, Vermeulen SH, Visser WE, Walsh JP, Westendorp RG, Widen E, Zhai G, Cucca F, Deary IJ, Eriksson JG, Ferrucci L, Fox CS, Jukema JW, Kiemeney LA, Pramstaller PP, Schlessinger D, Shuldiner AR, Slagboom EP, Uitterlinden AG, Vaidya B, Visser TJ, Wolffenbuttel BH, Meulenbelt I, Rotter JI, Spector TD, Hicks AA, Toniolo D, Sanna S, Peeters RP, Naitza S | 2013-01-01 | PLoS genetics | |
| Familial longevity is marked by better cognitive performance at middle age: the Leiden Longevity Study. | Stijntjes M, de Craen AJ, van Heemst D, Meskers CG, van Buchem MA, Westendorp RG, Slagboom PE, Maier AB | 2013-01-01 | PloS one | |
| Targeted biomarker discovery by high throughput glycosylation profiling of human plasma alpha1-antitrypsin and immunoglobulin A. | Ruhaak LR, Koeleman CA, Uh HW, Stam JC, van Heemst D, Maier AB, Houwing-Duistermaat JJ, Hensbergen PJ, Slagboom PE, Deelder AM, Wuhrer M | 2013-01-01 | PloS one | |
| The WHO maternal near miss approach: consequences at Malawian District level. | van den Akker T, Beltman J, Leyten J, Mwagomba B, Meguid T, Stekelenburg J, van Roosmalen J | 2013-01-01 | PloS one | |
| A descriptive analysis of HIV prevalence, HIV service uptake, and HIV-related risk behaviour among patients attending a mental health clinic in Rural Malawi. | Lommerse K, Stewart RC, Chilimba Q, van den Akker T, Lund C | 2013-01-01 | PloS one | |
| Ancestral stories of Ghanaian Bimoba reflect millennia-old genetic lineages. | Sanchez-Faddeev H, Pijpe J, van Bodegom D, van der Hulle T, van der Gaag KJ, Eriksson UK, Spear T, Westendorp RG, de Knijff P | 2013-01-01 | PloS one | |
| Low C-reactive protein levels in a traditional West-African population living in a malaria endemic area. | Eriksson UK, van Bodegom D, May L, Boef AG, Westendorp RG | 2013-01-01 | PloS one | |
| Socioeconomic status determines sex-dependent survival of human offspring. | van Bodegom D, Rozing MP, May L, Meij HJ, Thomése F, Zwaan BJ, Westendorp RG | 2013-01-01 | Africa, Trivers–Willard, offspring survival, offspring weight, reproduction, sex differences | Evolution, medicine, and public health |
| Deleterious alleles in the human genome are on average younger than neutral alleles of the same frequency. | Kiezun A, Pulit SL, Francioli LC, van Dijk F, Swertz M, Boomsma DI, van Duijn CM, Slagboom PE, van Ommen GJ, Wijmenga C, de Bakker PI, Sunyaev SR | 2013-01-01 | PLoS genetics | |
| High blood pressure, physical and cognitive function, and risk of stroke in the oldest old: the Leiden 85-plus Study. | Sabayan B, van Vliet P, de Ruijter W, Gussekloo J, de Craen AJ, Westendorp RG | 2013-01-01 | Stroke | |
| Blood pressure trends and mortality: the Leiden 85-plus Study. | Poortvliet RK, de Ruijter W, de Craen AJ, Mooijaart SP, Westendorp RG, Assendelft WJ, Gussekloo J, Blom JW | 2013-01-01 | Journal of hypertension | |
| Predictive value of a profile of routine blood measurements on mortality in older persons in the general population: the Leiden 85-plus Study. | van Houwelingen AH, den Elzen WP, Mooijaart SP, Heijmans M, Blom JW, de Craen AJ, Gussekloo J | 2013-01-01 | PloS one | |
| Subclinical thyroid dysfunction and cognitive decline in old age. | Wijsman LW, de Craen AJ, Trompet S, Gussekloo J, Stott DJ, Rodondi N, Welsh P, Jukema JW, Westendorp RG, Mooijaart SP | 2013-01-01 | PloS one | |
| NT-proBNP best predictor of cardiovascular events and cardiovascular mortality in secondary prevention in very old age: the Leiden 85-plus Study. | van Peet PG, Drewes YM, de Craen AJ, Gussekloo J, de Ruijter W | 2013-01-01 | PloS one | |
| The development of the Older Persons and Informal Caregivers Survey Minimum DataSet (TOPICS-MDS): a large-scale data sharing initiative. | Lutomski JE, Baars MA, Schalk BW, Boter H, Buurman BM, den Elzen WP, Jansen AP, Kempen GI, Steunenberg B, Steyerberg EW, Olde Rikkert MG, Melis RJ | 2013-01-01 | PloS one | |
| Microstructural white matter abnormalities and cognitive functioning in type 2 diabetes: a diffusion tensor imaging study. | Reijmer YD, Brundel M, de Bresser J, Kappelle LJ, Leemans A, Biessels GJ | 2013-01-01 | Diabetes care | |
| Semi-Automated Detection of Cerebral Microbleeds on 3.0 T MR Images. | Kuijf HJ, Brundel M, de Bresser J, van Veluw SJ, Heringa SM, Viergever MA, Biessels GJ, Vincken KL | 2013-01-01 | PloS one | |
| [Improved end-of-life care for patients with dementia: greater family satisfaction and possibly greater end-of-life comfort]. | van der Steen JT, van Soest-Poortvliet MC, Gijsberts MJ, Onwuteaka-Philipsen BD, Achterberg WP, Ribbe MW, Deliens L, de Vet HC | 2013-01-01 | Nederlands tijdschrift voor geneeskunde | |
| Pain management in patients with dementia. | Achterberg WP, Pieper MJ, van Dalen-Kok AH, de Waal MW, Husebo BS, Lautenbacher S, Kunz M, Scherder EJ, Corbett A | 2013-01-01 | Alzheimer’s disease, behavior, cognitive impairment, pain assessment | Clinical interventions in aging |
| Mortality in former Olympic athletes: retrospective cohort analysis. | Zwiers R, Zantvoord FW, Engelaer FM, van Bodegom D, van der Ouderaa FJ, Westendorp RG | 2012-12-13 | BMJ (Clinical research ed.) | |
| Levels of 25-hydroxyvitamin D in familial longevity: the Leiden Longevity Study. | Noordam R, de Craen AJ, Pedram P, Maier AB, Mooijaart SP, van Pelt J, Feskens EJ, Streppel MT, Slagboom PE, Westendorp RG, Beekman M, van Heemst D | 2012-12-11 | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne | |
| Brain tissue volumes in familial longevity: the Leiden Longevity Study. | Altmann-Schneider I, de Craen AJ, Slagboom PE, Westendorp RG, van Buchem MA, Maier AB, van der Grond J | 2012-12-01 | Aging cell | |
| Morphometric skin characteristics dependent on chronological and biological age: the Leiden Longevity Study. | Waaijer ME, Gunn DA, Catt SD, van Ginkel M, de Craen AJ, Hudson NM, van Heemst D, Slagboom PE, Westendorp RG, Maier AB | 2012-12-01 | Age (Dordrecht, Netherlands) | |
| The contribution of patient interviews to the identification of drug-related problems in home medication review. | Kwint HF, Faber A, Gussekloo J, Bouvy ML | 2012-12-01 | Journal of clinical pharmacy and therapeutics | |
| Predicting survival in oldest old people. | Taekema DG, Gussekloo J, Westendorp RG, de Craen AJ, Maier AB | 2012-12-01 | The American journal of medicine | |
| Proximity to death is associated with frequency of GP contacts in the oldest old: the Leiden 85-plus study. | Blom JW, Lemmens SP, Assendelft WJ, Eekhof JA, Gussekloo J | 2012-11-01 | Age and ageing | |
| Cutaneous wart-associated HPV types: prevalence and relation with patient characteristics. | Bruggink SC, de Koning MN, Gussekloo J, Egberts PF, Ter Schegget J, Feltkamp MC, Bavinck JN, Quint WG, Assendelft WJ, Eekhof JA | 2012-11-01 | Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology | |
| High blood pressure and resilience to physical and cognitive decline in the oldest old: the Leiden 85-plus Study. | Sabayan B, Oleksik AM, Maier AB, van Buchem MA, Poortvliet RK, de Ruijter W, Gussekloo J, de Craen AJ, Westendorp RG | 2012-11-01 | Journal of the American Geriatrics Society | |
| GPs’ perspectives on preventive care for older people: a focus group study. | Drewes YM, Koenen JM, de Ruijter W, van Dijk-van Dijk DJ, van der Weele GM, Middelkoop BJ, Reis R, Assendelft WJ, Gussekloo J | 2012-11-01 | The British journal of general practice : the journal of the Royal College of General Practitioners | |
| Hypertension in developing countries. | Koopman JJ, van Bodegom D, Beenakker KG, Jukema JW, Westendorp RG | 2012-10-27 | Lancet (London, England) | |
| Differences in signaling through the B-cell leukemia oncoprotein CRLF2 in response to TSLP and through mutant JAK2. | van Bodegom D, Zhong J, Kopp N, Dutta C, Kim MS, Bird L, Weigert O, Tyner J, Pandey A, Yoda A, Weinstock DM | 2012-10-04 | Blood | |
| Handgrip strength at midlife and familial longevity : The Leiden Longevity Study. | Ling CH, de Craen AJ, Slagboom PE, Westendorp RG, Maier AB | 2012-10-01 | Age (Dordrecht, Netherlands) | |
| Periconception maternal smoking and low education are associated with methylation of INSIGF in children at the age of 17 months. | Obermann-Borst SA, Heijmans BT, Eilers PH, Tobi EW, Steegers EA, Slagboom PE, Steegers-Theunissen RP | 2012-10-01 | Journal of developmental origins of health and disease | |
| Cortisol serum levels in familial longevity and perceived age: the Leiden longevity study. | Noordam R, Gunn DA, Tomlin CC, Rozing MP, Maier AB, Slagboom PE, Westendorp RG, van Heemst D, de Craen AJ | 2012-10-01 | Psychoneuroendocrinology | |
| Quantification of cerebral volumes on MRI 6 months after aneurysmal subarachnoid hemorrhage. | de Bresser J, Vincken KL, Kaspers AJ, Rinkel GJ, Viergever MA, Biessels GJ | 2012-10-01 | Stroke | |
| Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. | Zeggini E, Panoutsopoulou K, Southam L, Rayner NW, Day-Williams AG, Lopes MC, Boraska V, Esko T, Evangelou E, Hoffman A, Houwing-Duistermaat JJ, Ingvarsson T, Jonsdottir I, Jonnson H, Kerkhof HJ, Kloppenburg M, Bos SD, Mangino M, Metrustry S, Slagboom PE, Thorleifsson G, Raine EV, Ratnayake M, Ricketts M, Beazley C, Blackburn H, Bumpstead S, Elliott KS, Hunt SE, Potter SC, Shin SY, Yadav VK, Zhai G, Sherburn K, Dixon K, Arden E, Aslam N, Battley PK, Carluke I, Doherty S, Gordon A, Joseph J, Keen R, Koller NC, Mitchell S, O'Neill F, Paling E, Reed MR, Rivadeneira F, Swift D, Walker K, Watkins B, Wheeler M, Birrell F, Ioannidis JP, Meulenbelt I, Metspalu A, Rai A, Salter D, Stefansson K, Stykarsdottir U, Uitterlinden AG, van Meurs JB, Chapman K, Deloukas P, Ollier WE, Wallis GA, Arden N, Carr A, Doherty M, McCaskie A, Willkinson JM, Ralston SH, Valdes AM, Spector TD, Loughlin J | 2012-09-01 | Lancet (London, England) | |
| The continuing value of twin studies in the omics era. | van Dongen J, Slagboom PE, Draisma HH, Martin NG, Boomsma DI | 2012-09-01 | Nature reviews. Genetics | |
| Genetic variation in galectin-3 gene associates with cognitive function at old age. | Trompet S, Jukema W, Mooijaart SP, Ford I, Stott DJ, Westendorp RG, de Craen AJ | 2012-09-01 | Neurobiology of aging | |
| Gene dose of apolipoprotein E and age-related hearing loss. | Kurniawan C, Westendorp RG, de Craen AJ, Gussekloo J, de Laat J, van Exel E | 2012-09-01 | Neurobiology of aging | |
| Subclinical thyroid dysfunction and the risk of heart failure events: an individual participant data analysis from 6 prospective cohorts. | Gencer B, Collet TH, Virgini V, Bauer DC, Gussekloo J, Cappola AR, Nanchen D, den Elzen WP, Balmer P, Luben RN, Iacoviello M, Triggiani V, Cornuz J, Newman AB, Khaw KT, Jukema JW, Westendorp RG, Vittinghoff E, Aujesky D, Rodondi N | 2012-08-28 | Circulation | |
| BCL2 suppresses PARP1 function and nonapoptotic cell death. | Dutta C, Day T, Kopp N, van Bodegom D, Davids MS, Ryan J, Bird L, Kommajosyula N, Weigert O, Yoda A, Fung H, Brown JR, Shapiro GI, Letai A, Weinstock DM | 2012-08-15 | Cancer research | |
| Glucocorticoid receptor gene polymorphisms are associated with reduced first-phase glucose-stimulated insulin secretion and disposition index in women, but not in men. | van Raalte DH, van Leeuwen N, Simonis-Bik AM, Nijpels G, van Haeften TW, Schafer SA, Boomsma DI, Kramer MH, J Heine R, Maassen JA, Staiger H, Machicao F, Häring HU, Slagboom PE, Willemsen G, de Geus EJ, Dekker JM, Fritsche A, Eekhoff EM, Diamant M, 't Hart LM | 2012-08-01 | Diabetic medicine : a journal of the British Diabetic Association | |
| Epigenetic variation during the adult lifespan: cross-sectional and longitudinal data on monozygotic twin pairs. | Talens RP, Christensen K, Putter H, Willemsen G, Christiansen L, Kremer D, Suchiman HE, Slagboom PE, Boomsma DI, Heijmans BT | 2012-08-01 | Aging cell | |
| The number of p16INK4a positive cells in human skin reflects biological age. | Waaijer ME, Parish WE, Strongitharm BH, van Heemst D, Slagboom PE, de Craen AJ, Sedivy JM, Westendorp RG, Gunn DA, Maier AB | 2012-08-01 | Aging cell | |
| Responsiveness of the innate immune system and glucose concentrations in the oldest old. | Wijsman CA, Mooijaart SP, Westendorp RG, Maier AB | 2012-08-01 | Age (Dordrecht, Netherlands) | |
| Subclinical thyroid disorders. | Mooijaart SP | 2012-07-28 | Lancet (London, England) | |
| Subclinical thyroid disorders. | Quinn TJ, Gussekloo J, Kearney P, Rodondi N, Stott DJ | 2012-07-28 | Lancet (London, England) | |
| The place of genetics in ageing research. | Barzilai N, Guarente L, Kirkwood TB, Partridge L, Rando TA, Slagboom PE | 2012-07-10 | Nature reviews. Genetics | |
| A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts. | van Leeuwen N, Nijpels G, Becker ML, Deshmukh H, Zhou K, Stricker BH, Uitterlinden AG, Hofman A, van 't Riet E, Palmer CN, Guigas B, Slagboom PE, Durrington P, Calle RA, Neil A, Hitman G, Livingstone SJ, Colhoun H, Holman RR, McCarthy MI, Dekker JM, 't Hart LM, Pearson ER | 2012-07-01 | Diabetologia | |
| Increased type II deiodinase protein in OA-affected cartilage and allelic imbalance of OA risk polymorphism rs225014 at DIO2 in human OA joint tissues. | Bos SD, Bovée JV, Duijnisveld BJ, Raine EV, van Dalen WJ, Ramos YF, van der Breggen R, Nelissen RG, Slagboom PE, Loughlin J, Meulenbelt I | 2012-07-01 | Annals of the rheumatic diseases | |
| Microarray-based identification of age-dependent differences in gene expression of human dermal fibroblasts. | Dekker P, Gunn D, McBryan T, Dirks RW, van Heemst D, Lim FL, Jochemsen AG, Verlaan-de Vries M, Nagel J, Adams PD, Tanke HJ, Westendorp RG, Maier AB | 2012-07-01 | Mechanisms of ageing and development | |
| No increased mortality risk in older persons with unexplained anaemia. | Willems JM, den Elzen WP, Vlasveld LT, Westendorp RG, Gussekloo J, de Craen AJ, Blauw GJ | 2012-07-01 | Age and ageing | |
| Effects of a stepped-care intervention programme among older subjects who screened positive for depressive symptoms in general practice: the PROMODE randomised controlled trial. | van der Weele GM, de Waal MW, van den Hout WB, de Craen AJ, Spinhoven P, Stijnen T, Assendelft WJ, van der Mast RC, Gussekloo J | 2012-07-01 | Age and ageing | |
| Antibiotic use and resistance in long term care facilities. | van Buul LW, van der Steen JT, Veenhuizen RB, Achterberg WP, Schellevis FG, Essink RT, van Benthem BH, Natsch S, Hertogh CM | 2012-07-01 | Journal of the American Medical Directors Association | |
| CD4 testing at clinics to assess eligibility for antiretroviral therapy. | Lumala R, van den Akker T, Metcalf CA, Diggle E, Zamadenga B, Mbewa K, Akkeson A | 2012-06-01 | Malawi medical journal : the journal of Medical Association of Malawi | |
| Nonreferral of nursing home patients with suspected breast cancer. | Hamaker ME, Hamelinck VC, van Munster BC, Bastiaannet E, Smorenburg CH, Achterberg WP, Liefers GJ, de Rooij SE | 2012-06-01 | Journal of the American Medical Directors Association | |
| The influence of the administration method on scores of the 15-item Geriatric Depression Scale in old age. | de Waal MW, van der Weele GM, van der Mast RC, Assendelft WJ, Gussekloo J | 2012-05-30 | Psychiatry research | |
| Subclinical hyperthyroidism and the risk of coronary heart disease and mortality. | Collet TH, Gussekloo J, Bauer DC, den Elzen WP, Cappola AR, Balmer P, Iervasi G, Åsvold BO, Sgarbi JA, Völzke H, Gencer B, Maciel RM, Molinaro S, Bremner A, Luben RN, Maisonneuve P, Cornuz J, Newman AB, Khaw KT, Westendorp RG, Franklyn JA, Vittinghoff E, Walsh JP, Rodondi N | 2012-05-28 | Archives of internal medicine | |
| How to deal with the early GWAS data when imputing and combining different arrays is necessary. | Uh HW, Deelen J, Beekman M, Helmer Q, Rivadeneira F, Hottenga JJ, Boomsma DI, Hofman A, Uitterlinden AG, Slagboom PE, Böhringer S, Houwing-Duistermaat JJ | 2012-05-01 | European journal of human genetics : EJHG | |
| Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies. | Soerensen M, Dato S, Tan Q, Thinggaard M, Kleindorp R, Beekman M, Jacobsen R, Suchiman HE, de Craen AJ, Westendorp RG, Schreiber S, Stevnsner T, Bohr VA, Slagboom PE, Nebel A, Vaupel JW, Christensen K, McGue M, Christiansen L | 2012-05-01 | Experimental gerontology | |
| Pharmacogenetics of statins: achievements, whole-genome analyses and future perspectives. | Postmus I, Verschuren JJ, de Craen AJ, Slagboom PE, Westendorp RG, Jukema JW, Trompet S | 2012-05-01 | Pharmacogenomics | |
| Chronic inhibition of the respiratory chain in human fibroblast cultures: differential responses related to subject chronological and biological age. | Dekker P, van Baalen LM, Dirks RW, Slagboom PE, van Heemst D, Tanke HJ, Westendorp RG, Maier AB | 2012-05-01 | The journals of gerontology. Series A, Biological sciences and medical sciences | |
| Barriers to conducting effective obstetric audit in Ifakara: a qualitative assessment in an under-resourced setting in Tanzania. | van Hamersveld KT, den Bakker E, Nyamtema AS, van den Akker T, Mfinanga EH, van Elteren M, van Roosmalen J | 2012-05-01 | Tropical medicine & international health : TM & IH | |
| Cerebral haemodynamics, cognition and brain volumes in patients with type 2 diabetes. | Brundel M, van den Berg E, Reijmer YD, de Bresser J, Kappelle LJ, Biessels GJ | 2012-05-01 | Journal of diabetes and its complications | |
| Psychometric properties of instruments to measure the quality of end-of-life care and dying for long-term care residents with dementia. | van Soest-Poortvliet MC, van der Steen JT, Zimmerman S, Cohen LW, Klapwijk MS, Bezemer M, Achterberg WP, Knol DL, Ribbe MW, de Vet HC | 2012-05-01 | Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation | |
| Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. | Estrada K, Styrkarsdottir U, Evangelou E, Hsu YH, Duncan EL, Ntzani EE, Oei L, Albagha OM, Amin N, Kemp JP, Koller DL, Li G, Liu CT, Minster RL, Moayyeri A, Vandenput L, Willner D, Xiao SM, Yerges-Armstrong LM, Zheng HF, Alonso N, Eriksson J, Kammerer CM, Kaptoge SK, Leo PJ, Thorleifsson G, Wilson SG, Wilson JF, Aalto V, Alen M, Aragaki AK, Aspelund T, Center JR, Dailiana Z, Duggan DJ, Garcia M, Garcia-Giralt N, Giroux S, Hallmans G, Hocking LJ, Husted LB, Jameson KA, Khusainova R, Kim GS, Kooperberg C, Koromila T, Kruk M, Laaksonen M, Lacroix AZ, Lee SH, Leung PC, Lewis JR, Masi L, Mencej-Bedrac S, Nguyen TV, Nogues X, Patel MS, Prezelj J, Rose LM, Scollen S, Siggeirsdottir K, Smith AV, Svensson O, Trompet S, Trummer O, van Schoor NM, Woo J, Zhu K, Balcells S, Brandi ML, Buckley BM, Cheng S, Christiansen C, Cooper C, Dedoussis G, Ford I, Frost M, Goltzman D, González-Macías J, Kähönen M, Karlsson M, Khusnutdinova E, Koh JM, Kollia P, Langdahl BL, Leslie WD, Lips P, Ljunggren Ö, Lorenc RS, Marc J, Mellström D, Obermayer-Pietsch B, Olmos JM, Pettersson-Kymmer U, Reid DM, Riancho JA, Ridker PM, Rousseau F, Slagboom PE, Tang NL, Urreizti R, Van Hul W, Viikari J, Zarrabeitia MT, Aulchenko YS, Castano-Betancourt M, Grundberg E, Herrera L, Ingvarsson T, Johannsdottir H, Kwan T, Li R, Luben R, Medina-Gómez C, Palsson ST, Reppe S, Rotter JI, Sigurdsson G, van Meurs JB, Verlaan D, Williams FM, Wood AR, Zhou Y, Gautvik KM, Pastinen T, Raychaudhuri S, Cauley JA, Chasman DI, Clark GR, Cummings SR, Danoy P, Dennison EM, Eastell R, Eisman JA, Gudnason V, Hofman A, Jackson RD, Jones G, Jukema JW, Khaw KT, Lehtimäki T, Liu Y, Lorentzon M, McCloskey E, Mitchell BD, Nandakumar K, Nicholson GC, Oostra BA, Peacock M, Pols HA, Prince RL, Raitakari O, Reid IR, Robbins J, Sambrook PN, Sham PC, Shuldiner AR, Tylavsky FA, van Duijn CM, Wareham NJ, Cupples LA, Econs MJ, Evans DM, Harris TB, Kung AW, Psaty BM, Reeve J, Spector TD, Streeten EA, Zillikens MC, Thorsteinsdottir U, Ohlsson C, Karasik D, Richards JB, Brown MA, Stefansson K, Uitterlinden AG, Ralston SH, Ioannidis JP, Kiel DP, Rivadeneira F | 2012-04-15 | Nature genetics | |
| Parental longevity correlates with offspring’s optimism in two cohorts of community-dwelling older subjects. | Rius-Ottenheim N, Kromhout D, de Craen AJ, Geleijnse JM, van der Mast RC, Zitman FG, Westendorp RG, Slagboom PE, Giltay EJ | 2012-04-01 | Age (Dordrecht, Netherlands) | |
| Literature-based genetic risk scores for coronary heart disease: the Cardiovascular Registry Maastricht (CAREMA) prospective cohort study. | Vaarhorst AA, Lu Y, Heijmans BT, Dollé ME, Böhringer S, Putter H, Imholz S, Merry AH, van Greevenbroek MM, Jukema JW, Gorgels AP, van den Brandt PA, Müller M, Schouten LJ, Feskens EJ, Boer JM, Slagboom PE | 2012-04-01 | Circulation. Cardiovascular genetics | |
| The maintenance gap: a new theoretical perspective on the evolution of aging. | Wensink MJ, van Heemst D, Rozing MP, Westendorp RG | 2012-04-01 | Biogerontology | |
| Diabetic retinopathy screening in patients with diabetes mellitus in primary care: Incentives and barriers to screening attendance. | van Eijk KN, Blom JW, Gussekloo J, Polak BC, Groeneveld Y | 2012-04-01 | Diabetes research and clinical practice | |
| The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. | Swerdlow DI, Holmes MV, Kuchenbaecker KB, Engmann JE, Shah T, Sofat R, Guo Y, Chung C, Peasey A, Pfister R, Mooijaart SP, Ireland HA, Leusink M, Langenberg C, Li KW, Palmen J, Howard P, Cooper JA, Drenos F, Hardy J, Nalls MA, Li YR, Lowe G, Stewart M, Bielinski SJ, Peto J, Timpson NJ, Gallacher J, Dunlop M, Houlston R, Tomlinson I, Tzoulaki I, Luan J, Boer JM, Forouhi NG, Onland-Moret NC, van der Schouw YT, Schnabel RB, Hubacek JA, Kubinova R, Baceviciene M, Tamosiunas A, Pajak A, Topor-Madry R, Malyutina S, Baldassarre D, Sennblad B, Tremoli E, de Faire U, Ferrucci L, Bandenelli S, Tanaka T, Meschia JF, Singleton A, Navis G, Mateo Leach I, Bakker SJ, Gansevoort RT, Ford I, Epstein SE, Burnett MS, Devaney JM, Jukema JW, Westendorp RG, Jan de Borst G, van der Graaf Y, de Jong PA, Mailand-van der Zee AH, Klungel OH, de Boer A, Doevendans PA, Stephens JW, Eaton CB, Robinson JG, Manson JE, Fowkes FG, Frayling TM, Price JF, Whincup PH, Morris RW, Lawlor DA, Smith GD, Ben-Shlomo Y, Redline S, Lange LA, Kumari M, Wareham NJ, Verschuren WM, Benjamin EJ, Whittaker JC, Hamsten A, Dudbridge F, Delaney JA, Wong A, Kuh D, Hardy R, Castillo BA, Connolly JJ, van der Harst P, Brunner EJ, Marmot MG, Wassel CL, Humphries SE, Talmud PJ, Kivimaki M, Asselbergs FW, Voevoda M, Bobak M, Pikhart H, Wilson JG, Hakonarson H, Reiner AP, Keating BJ, Sattar N, Hingorani AD, Casas JP | 2012-03-31 | Lancet (London, England) | |
| Human in vivo longevity is reflected in vitro by differential metabolism as measured by (1)H-NMR profiling of cell culture supernatants. | Dekker P, Meissner A, Dirks RW, Eline Slagboom P, van Heemst D, Deelder AM, Tanke HJ, Westendorp RG, Maier AB | 2012-03-01 | Molecular bioSystems | |
| HIV care need not hamper maternity care: a descriptive analysis of integration of services in rural Malawi. | van den Akker T, Bemelmans M, Ford N, Jemu M, Diggle E, Scheffer S, Zulu I, Akesson A, Shea J | 2012-03-01 | BJOG : an international journal of obstetrics and gynaecology | |
| Subclinical thyroid dysfunction and the risk of heart failure in older persons at high cardiovascular risk. | Nanchen D, Gussekloo J, Westendorp RG, Stott DJ, Jukema JW, Trompet S, Ford I, Welsh P, Sattar N, Macfarlane PW, Mooijaart SP, Rodondi N, de Craen AJ | 2012-03-01 | The Journal of clinical endocrinology and metabolism | |
| Cerebral microinfarcts: a systematic review of neuropathological studies. | Brundel M, de Bresser J, van Dillen JJ, Kappelle LJ, Biessels GJ | 2012-03-01 | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism | |
| PASSion: a pattern growth algorithm-based pipeline for splice junction detection in paired-end RNA-Seq data. | Zhang Y, Lameijer EW, 't Hoen PA, Ning Z, Slagboom PE, Ye K | 2012-02-15 | Bioinformatics (Oxford, England) | |
| Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition. | Weigert O, Lane AA, Bird L, Kopp N, Chapuy B, van Bodegom D, Toms AV, Marubayashi S, Christie AL, McKeown M, Paranal RM, Bradner JE, Yoda A, Gaul C, Vangrevelinghe E, Romanet V, Murakami M, Tiedt R, Ebel N, Evrot E, De Pover A, Régnier CH, Erdmann D, Hofmann F, Eck MJ, Sallan SE, Levine RL, Kung AL, Baffert F, Radimerski T, Weinstock DM | 2012-02-13 | The Journal of experimental medicine | |
| Hypermethylation at loci sensitive to the prenatal environment is associated with increased incidence of myocardial infarction. | Talens RP, Jukema JW, Trompet S, Kremer D, Westendorp RG, Lumey LH, Sattar N, Putter H, Slagboom PE, Heijmans BT | 2012-02-01 | International journal of epidemiology | |
| Serum triiodothyronine levels and inflammatory cytokine production capacity. | Rozing MP, Westendorp RG, Maier AB, Wijsman CA, Frölich M, de Craen AJ, van Heemst D | 2012-02-01 | Age (Dordrecht, Netherlands) | |
| The influence of genetic variation on innate immune activation in an environment with high infectious pressure. | Boef AG, May L, van Bodegom D, Kuningas M, Eriksson UK, Westendorp RG | 2012-02-01 | Genes and immunity | |
| Proton magnetic resonance spectroscopy shows lower intramyocellular lipid accumulation in middle-aged subjects predisposed to familial longevity. | Wijsman CA, van Opstal AM, Kan HE, Maier AB, Westendorp RG, Slagboom PE, Webb AG, Mooijaart SP, van Heemst D | 2012-02-01 | American journal of physiology. Endocrinology and metabolism | |
| Response to an unsolicited intervention offer to persons aged ≥ 75 years after screening positive for depressive symptoms: a qualitative study. | van der Weele GM, de Jong R, de Waal MW, Spinhoven P, Rooze HA, Reis R, Assendelft WJ, Gussekloo J, van der Mast RC | 2012-02-01 | International psychogeriatrics | |
| Efficient detection of cerebral microbleeds on 7.0 T MR images using the radial symmetry transform. | Kuijf HJ, de Bresser J, Geerlings MI, Conijn MM, Viergever MA, Biessels GJ, Vincken KL | 2012-02-01 | NeuroImage | |
| Hypotension is more risky than hypertension in very old people. | Engelaer FM, van Bodegom D, Westendorp RG | 2012-01-31 | BMJ (Clinical research ed.) | |
| C-reactive protein haplotypes and dispositional optimism in obese and nonobese elderly subjects. | Rius-Ottenheim N, de Craen AJ, Geleijnse JM, Slagboom PE, Kromhout D, van der Mast RC, Zitman FG, Westendorp RG, Giltay EJ | 2012-01-01 | Inflammation research : official journal of the European Histamine Research Society ... [et al.] | |
| Common variants in the type 2 diabetes KCNQ1 gene are associated with impairments in insulin secretion during hyperglycaemic glucose clamp. | van Vliet-Ostaptchouk JV, van Haeften TW, Landman GW, Reiling E, Kleefstra N, Bilo HJ, Klungel OH, de Boer A, van Diemen CC, Wijmenga C, Boezen HM, Dekker JM, van 't Riet E, Nijpels G, Welschen LM, Zavrelova H, Bruin EJ, Elbers CC, Bauer F, Onland-Moret NC, van der Schouw YT, Grobbee DE, Spijkerman AM, van der A DL, Simonis-Bik AM, Eekhoff EM, Diamant M, Kramer MH, Boomsma DI, de Geus EJ, Willemsen G, Slagboom PE, Hofker MH, 't Hart LM | 2012-01-01 | PloS one | |
| Prenatal famine and genetic variation are independently and additively associated with DNA methylation at regulatory loci within IGF2/H19. | Tobi EW, Slagboom PE, van Dongen J, Kremer D, Stein AD, Putter H, Heijmans BT, Lumey LH | 2012-01-01 | PloS one | |
| Genome-wide study of gene variants associated with differential cardiovascular event reduction by pravastatin therapy. | Shiffman D, Trompet S, Louie JZ, Rowland CM, Catanese JJ, Iakoubova OA, Kirchgessner TG, Westendorp RG, de Craen AJ, Slagboom PE, Buckley BM, Stott DJ, Sattar N, Devlin JJ, Packard CJ, Ford I, Sacks FM, Jukema JW | 2012-01-01 | PloS one | |
| Systematic testing of literature reported genetic variation associated with coronary restenosis: results of the GENDER Study. | Verschuren JJ, Trompet S, Postmus I, Sampietro ML, Heijmans BT, Houwing-Duistermaat JJ, Slagboom PE, Jukema JW | 2012-01-01 | PloS one | |
| Markers of endogenous desaturase activity and risk of coronary heart disease in the CAREMA cohort study. | Lu Y, Vaarhorst A, Merry AH, Dollé ME, Hovenier R, Imholz S, Schouten LJ, Heijmans BT, Müller M, Slagboom PE, van den Brandt PA, Gorgels AP, Boer JM, Feskens EJ | 2012-01-01 | PloS one | |
| Marked heterogeneity in growth characteristics of myoblast clonal cultures and myoblast mixed cultures obtained from the same individual. | Maier AB, Cohen R, Blom J, van Heemst D, Westendorp RG | 2012-01-01 | Gerontology | |
| Transcriptional profiling of human familial longevity indicates a role for ASF1A and IL7R. | Passtoors WM, Boer JM, Goeman JJ, Akker EB, Deelen J, Zwaan BJ, Scarborough A, Breggen Rv, Vossen RH, Houwing-Duistermaat JJ, Ommen GJ, Westendorp RG, van Heemst D, de Craen AJ, White AJ, Gunn DA, Beekman M, Slagboom PE | 2012-01-01 | PloS one | |
| Familial longevity is marked by lower diurnal salivary cortisol levels: the Leiden Longevity Study. | Noordam R, Jansen SW, Akintola AA, Oei NY, Maier AB, Pijl H, Slagboom PE, Westendorp RG, van der Grond J, de Craen AJ, van Heemst D | 2012-01-01 | PloS one | |
| Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. | Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, Lyytikäinen LP, Fuchsberger C, Tanaka T, Morris AP, Small K, Isaacs A, Beekman M, Coassin S, Lohman K, Qi L, Kanoni S, Pankow JS, Uh HW, Wu Y, Bidulescu A, Rasmussen-Torvik LJ, Greenwood CM, Ladouceur M, Grimsby J, Manning AK, Liu CT, Kooner J, Mooser VE, Vollenweider P, Kapur KA, Chambers J, Wareham NJ, Langenberg C, Frants R, Willems-Vandijk K, Oostra BA, Willems SM, Lamina C, Winkler TW, Psaty BM, Tracy RP, Brody J, Chen I, Viikari J, Kähönen M, Pramstaller PP, Evans DM, St Pourcain B, Sattar N, Wood AR, Bandinelli S, Carlson OD, Egan JM, Böhringer S, van Heemst D, Kedenko L, Kristiansson K, Nuotio ML, Loo BM, Harris T, Garcia M, Kanaya A, Haun M, Klopp N, Wichmann HE, Deloukas P, Katsareli E, Couper DJ, Duncan BB, Kloppenburg M, Adair LS, Borja JB, Wilson JG, Musani S, Guo X, Johnson T, Semple R, Teslovich TM, Allison MA, Redline S, Buxbaum SG, Mohlke KL, Meulenbelt I, Ballantyne CM, Dedoussis GV, Hu FB, Liu Y, Paulweber B, Spector TD, Slagboom PE, Ferrucci L, Jula A, Perola M, Raitakari O, Florez JC, Salomaa V, Eriksson JG, Frayling TM, Hicks AA, Lehtimäki T, Smith GD, Siscovick DS, Kronenberg F, van Duijn C, Loos RJ, Waterworth DM, Meigs JB, Dupuis J, Richards JB, Voight BF, Scott LJ, Steinthorsdottir V, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Hofmann OM, Segrè AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Boström KB, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jørgensen T, Kao WH, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Petersen AK, Platou C, Proença C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparsø T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Morris AD, Palmer CN, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Pedersen O, Barroso I, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI, Soranzo N, Wheeler E, Glazer NL, Bouatia-Naji N, Mägi R, Randall J, Elliott P, Rybin D, Dehghan A, Hottenga JJ, Song K, Goel A, Lajunen T, Doney A, Cavalcanti-Proença C, Kumari M, Timpson NJ, Zabena C, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Roccasecca RM, Pattou F, Sethupathy P, Ariyurek Y, Barter P, Beilby JP, Ben-Shlomo Y, Bergmann S, Bochud M, Bonnefond A, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead SJ, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Crisponi L, Day IN, de Geus EJ, Delplanque J, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Grundy S, Gwilliam R, Hallmans G, Hammond N, Han X, Hartikainen AL, Hayward C, Heath SC, Hercberg S, Hillman DR, Hingorani AD, Hui J, Hung J, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Mahley R, Mangino M, Martínez-Larrad MT, McAteer JB, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Mukherjee S, Naitza S, Neville MJ, Orrù M, Pakyz R, Paolisso G, Pattaro C, Pearson D, Peden JF, Pedersen NL, Pfeiffer AF, Pichler I, Polasek O, Posthuma D, Potter SC, Pouta A, Province MA, Rayner NW, Rice K, Ripatti S, Rivadeneira F, Rolandsson O, Sandbaek A, Sandhu M, Sanna S, Sayer AA, Scheet P, Seedorf U, Sharp SJ, Shields B, Sigurðsson G, Sijbrands EJ, Silveira A, Simpson L, Singleton A, Smith NL, Sovio U, Swift A, Syddall H, Syvänen AC, Tönjes A, Uitterlinden AG, van Dijk KW, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, Wagner PJ, Walley A, Ward KL, Watkins H, Wild SH, Willemsen G, Witteman JC, Yarnell JW, Zelenika D, Zethelius B, Zhai G, Zhao JH, Zillikens MC, Borecki IB, Meneton P, Magnusson PK, Nathan DM, Williams GH, Silander K, Bornstein SR, Schwarz P, Spranger J, Karpe F, Shuldiner AR, Cooper C, Serrano-Ríos M, Lind L, Palmer LJ, Hu FB, Franks PW, Ebrahim S, Marmot M, Kao WH, Pramstaller PP, Wright AF, Stumvoll M, Hamsten A, Buchanan TA, Valle TT, Rotter JI, Penninx BW, Boomsma DI, Cao A, Scuteri A, Schlessinger D, Uda M, Ruokonen A, Jarvelin MR, Peltonen L, Mooser V, Sladek R, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Chasman DI, Johansen CT, Fouchier SW, Peloso GM, Barbalic M, Ricketts SL, Bis JC, Feitosa MF, Orho-Melander M, Melander O, Li X, Li M, Cho YS, Go MJ, Kim YJ, Lee JY, Park T, Kim K, Sim X, Ong RT, Croteau-Chonka DC, Lange LA, Smith JD, Ziegler A, Zhang W, Zee RY, Whitfield JB, Thompson JR, Surakka I, Spector TD, Smit JH, Sinisalo J, Scott J, Saharinen J, Sabatti C, Rose LM, Roberts R, Rieder M, Parker AN, Pare G, O'Donnell CJ, Nieminen MS, Nickerson DA, Montgomery GW, McArdle W, Masson D, Martin NG, Marroni F, Lucas G, Luben R, Lokki ML, Lettre G, Launer LJ, Lakatta EG, Laaksonen R, Kyvik KO, König IR, Khaw KT, Kaplan LM, Johansson Å, Janssens AC, Igl W, Hovingh GK, Hengstenberg C, Havulinna AS, Hastie ND, Harris TB, Haritunians T, Hall AS, Groop LC, Gonzalez E, Freimer NB, Erdmann J, Ejebe KG, Döring A, Dominiczak AF, Demissie S, Deloukas P, de Faire U, Crawford G, Chen YD, Caulfield MJ, Boekholdt SM, Assimes TL, Quertermous T, Seielstad M, Wong TY, Tai ES, Feranil AB, Kuzawa CW, Taylor HA, Gabriel SB, Holm H, Gudnason V, Krauss RM, Ordovas JM, Munroe PB, Kooner JS, Tall AR, Hegele RA, Kastelein JJ, Schadt EE, Strachan DP, Reilly MP, Samani NJ, Schunkert H, Cupples LA, Sandhu MS, Ridker PM, Rader DJ, Kathiresan S | 2012-01-01 | PLoS genetics | |
| Risk of cardiovascular disease in a traditional African population with a high infectious load: a population-based study. | Koopman JJ, van Bodegom D, Jukema JW, Westendorp RG | 2012-01-01 | PloS one | |
| Clustering of child mortality in a contemporary polygamous population in Africa. | Van Bodegom D, Eriksson UK, Houwing-Duistermaat JJ, Westendorp RG | 2012-01-01 | Biodemography and social biology | |
| [Should subclinical hypothyroidism in older persons be treated?]. | den Elzen WP, Smit JW, Mooijaart SP, Gussekloo J | 2012-01-01 | Nederlands tijdschrift voor geneeskunde | |
| Assessment of appropriateness of screening community-dwelling older people to prevent functional decline. | Drewes YM, Gussekloo J, van der Meer V, Rigter H, Dekker JH, Goumans MJ, Metsemakers JF, van Overbeek R, de Rooij SE, Schers HJ, Schuurmans MJ, Sturmans F, de Vries K, Westendorp RG, Wind AW, Assendelft WJ | 2012-01-01 | Journal of the American Geriatrics Society | |
| Total joint replacement in the past does not relate to a deteriorated functional level and health status in the oldest old. | Verra WC, de Craen AJ, Jaspars CC, Gussekloo J, Blauw GJ, Westendorp RG, Maier AB, Nelissen RG | 2012-01-01 | Journal of aging research | |
| [The guideline ‘Cardiovascular risk management’ is too simplified for elderly care]. | de Ruijter W, Gussekloo J | 2012-01-01 | Nederlands tijdschrift voor geneeskunde | |
| [Should subclinical hypothyroidism in older persons be treated?]. | den Elzen WP, Smit JW, Mooijaart SP, Gussekloo J | 2012-01-01 | Nederlands tijdschrift voor geneeskunde | |
| Blood pressure variability and cardiovascular risk in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER). | Poortvliet RK, Ford I, Lloyd SM, Sattar N, Mooijaart SP, de Craen AJ, Westendorp RG, Jukema JW, Packard CJ, Gussekloo J, de Ruijter W, Stott DJ | 2012-01-01 | PloS one | |
| High prevalence of cerebral microbleeds at 7Tesla MRI in patients with early Alzheimer’s disease. | Brundel M, Heringa SM, de Bresser J, Koek HL, Zwanenburg JJ, Jaap Kappelle L, Luijten PR, Biessels GJ | 2012-01-01 | Journal of Alzheimer's disease : JAD | |
| Definition of urinary tract infection in nursing homes. | Achterberg WP, Went PB | 2012-01-01 | The Journal of hospital infection | |
| [Multidisciplinary guideline ‘Recognition and treatment of chronic pain in vulnerable elderly people’]. | Achterberg WP, de Ruiter CM, de Weerd-Spaetgens CM, Geels P, Horikx A, Verduijn MM | 2012-01-01 | Nederlands tijdschrift voor geneeskunde | |
| [Hip fracture in patients with dementia: surgery is not always the best alternative]. | Meijer-Schafrat EC, Janssens JF, van Delden JJ, Achterberg WP | 2012-01-01 | Nederlands tijdschrift voor geneeskunde | |
| Integrating protein-protein interaction networks with gene-gene co-expression networks improves gene signatures for classifying breast cancer metastasis. | van den Akker EB, Verbruggen B, Heijmans BT, Beekman M, Kok JN, Slagboom PE, Reinders MJ | 2011-12-16 | Journal of integrative bioinformatics | |
| A genome-wide association study identifies a region at chromosome 12 as a potential susceptibility locus for restenosis after percutaneous coronary intervention. | Sampietro ML, Trompet S, Verschuren JJ, Talens RP, Deelen J, Heijmans BT, de Winter RJ, Tio RA, Doevendans PA, Ganesh SK, Nabel EG, Westra HJ, Franke L, van den Akker EB, Westendorp RG, Zwinderman AH, Kastrati A, Koch W, Slagboom PE, de Knijff P, Jukema JW | 2011-12-01 | Human molecular genetics | |
| Beyond maternal mortality: obstetric hemorrhage in a Malawian district. | Beltman J, VAN DEN Akker T, VAN Lonkhuijzen L, Schmidt A, Chidakwani R, VAN Roosmalen J | 2011-12-01 | Acta obstetricia et gynecologica Scandinavica | |
| C-reactive protein and glucose regulation in familial longevity. | Rozing MP, Mooijaart SP, Beekman M, Wijsman CA, Maier AB, Bartke A, Westendorp RG, Slagboom EP, van Heemst D | 2011-12-01 | Age (Dordrecht, Netherlands) | |
| The inverse relationship between alanine aminotransferase in the normal range and adverse cardiovascular and non-cardiovascular outcomes. | Ford I, Mooijaart SP, Lloyd S, Murray HM, Westendorp RG, de Craen AJ, Packard CJ, Buckley B, Barlow C, Preiss D, Cobbe SM, Stott DJ, Sattar N | 2011-12-01 | International journal of epidemiology | |
| Measuring the quality of dying and quality of care when dying in long-term care settings: a qualitative content analysis of available instruments. | van Soest-Poortvliet MC, van der Steen JT, Zimmerman S, Cohen LW, Munn J, Achterberg WP, Ribbe MW, de Vet HC | 2011-12-01 | Journal of pain and symptom management | |
| A mixture model with random-effects components for classifying sibling pairs. | Martella F, Vermunt JK, Beekman M, Westendorp RG, Slagboom PE, Houwing-Duistermaat JJ | 2011-11-30 | Statistics in medicine | |
| Design, recruitment, logistics, and data management of the GEHA (Genetics of Healthy Ageing) project. | Skytthe A, Valensin S, Jeune B, Cevenini E, Balard F, Beekman M, Bezrukov V, Blanche H, Bolund L, Broczek K, Carru C, Christensen K, Christiansen L, Collerton JC, Cotichini R, de Craen AJ, Dato S, Davies K, De Benedictis G, Deiana L, Flachsbart F, Gampe J, Gilbault C, Gonos ES, Haimes E, Hervonen A, Hurme MA, Janiszewska D, Jylhä M, Kirkwood TB, Kristensen P, Laiho P, Leon A, Marchisio A, Masciulli R, Nebel A, Passarino G, Pelicci G, Peltonen L, Perola M, Poulain M, Rea IM, Remacle J, Robine JM, Schreiber S, Scurti M, Sevini F, Sikora E, Skouteri A, Slagboom PE, Spazzafumo L, Stazi MA, Toccaceli V, Toussaint O, Törnwall O, Vaupel JW, Voutetakis K, Franceschi C | 2011-11-01 | Experimental gerontology | |
| Replication of LDL GWAs hits in PROSPER/PHASE as validation for future (pharmaco)genetic analyses. | Trompet S, de Craen AJ, Postmus I, Ford I, Sattar N, Caslake M, Stott DJ, Buckley BM, Sacks F, Devlin JJ, Slagboom PE, Westendorp RG, Jukema JW | 2011-10-06 | BMC medical genetics | |
| Accuracy of direct segmental multi-frequency bioimpedance analysis in the assessment of total body and segmental body composition in middle-aged adult population. | Ling CH, de Craen AJ, Slagboom PE, Gunn DA, Stokkel MP, Westendorp RG, Maier AB | 2011-10-01 | Clinical nutrition (Edinburgh, Scotland) | |
| Abdominal fat accumulation in adults born preterm exposed antenatally to maternal glucocorticoid treatment is dependent on glucocorticoid receptor gene variation. | Finken MJ, Meulenbelt I, Dekker FW, Frölich M, Walther FJ, Romijn JA, Slagboom PE, Wit JM | 2011-10-01 | The Journal of clinical endocrinology and metabolism | |
| Health workers’ perceptions of obstetric critical incident audit in Thyolo District, Malawi. | Bakker W, van den Akker T, Mwagomba B, Khukulu R, van Elteren M, van Roosmalen J | 2011-10-01 | Tropical medicine & international health : TM & IH | |
| Lesional HPV types of cutaneous warts can be reliably identified by surface swabs. | de Koning MN, Khoe LV, Eekhof JA, Kamp M, Gussekloo J, Ter Schegget J, Bouwes Bavinck JN, Quint WG | 2011-10-01 | Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology | |
| Body mass index and alignment and their interaction as risk factors for progression of knees with radiographic signs of osteoarthritis. | Yusuf E, Bijsterbosch J, Slagboom PE, Rosendaal FR, Huizinga TW, Kloppenburg M | 2011-09-01 | Osteoarthritis and cartilage | |
| Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited. | Deelen J, Beekman M, Uh HW, Helmer Q, Kuningas M, Christiansen L, Kremer D, van der Breggen R, Suchiman HE, Lakenberg N, van den Akker EB, Passtoors WM, Tiemeier H, van Heemst D, de Craen AJ, Rivadeneira F, de Geus EJ, Perola M, van der Ouderaa FJ, Gunn DA, Boomsma DI, Uitterlinden AG, Christensen K, van Duijn CM, Heijmans BT, Houwing-Duistermaat JJ, Westendorp RG, Slagboom PE | 2011-08-01 | Aging cell | |
| Peripartum infections and associated maternal mortality in rural Malawi. | van den Akker T, de Vroome S, Mwagomba B, Ford N, van Roosmalen J | 2011-08-01 | Obstetrics and gynecology | |
| Association between leptin, adiponectin and resistin and long-term progression of hand osteoarthritis. | Yusuf E, Ioan-Facsinay A, Bijsterbosch J, Klein-Wieringa I, Kwekkeboom J, Slagboom PE, Huizinga TW, Kloppenburg M | 2011-07-01 | Annals of the rheumatic diseases | |
| Reduced tuberculosis case notification associated with scaling up antiretroviral treatment in rural Malawi. | Zachariah R, Bemelmans M, Akesson A, Gomani P, Phiri K, Isake B, van den Akker T, Philips M, Mwale A, Gausi F, Kwanjana J, Harries AD | 2011-07-01 | The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease | |
| Telomere length and anaemia in old age: results from the Newcastle 85-plus Study and the Leiden 85-plus Study. | Den Elzen WP, Martin-Ruiz C, von Zglinicki T, Westendorp RG, Kirkwood TB, Gussekloo J | 2011-07-01 | Age and ageing | |
| Cytomegalovirus infection and responsiveness to influenza vaccination in elderly residents of long-term care facilities. | den Elzen WP, Vossen AC, Cools HJ, Westendorp RG, Kroes AC, Gussekloo J | 2011-06-24 | Vaccine | |
| Lipid metabolism in long-lived families: the Leiden Longevity Study. | Vaarhorst AA, Beekman M, Suchiman EH, van Heemst D, Houwing-Duistermaat JJ, Westendorp RG, Slagboom PE, Heijmans BT | 2011-06-01 | Age (Dordrecht, Netherlands) | |
| Variation in DNA damage response pathway activity: focus on intermediate phenotype instead of genetic polymorphisms. | van Heemst D | 2011-06-01 | Cell cycle (Georgetown, Tex.) | |
| Anaemia in older persons. | den Elzen WP, Gussekloo J | 2011-06-01 | The Netherlands journal of medicine | |
| Predictive factors of urinary tract infections among the oldest old in the general population. A population-based prospective follow-up study. | Caljouw MA, den Elzen WP, Cools HJ, Gussekloo J | 2011-05-16 | BMC medicine | |
| Repetition of a sisterhood survey at district level in Malawi: the challenge to achieve MDG 5. | Beltman JJ, van den Akker T, Lam E, Moens M, Kazima J, Massaquoi M, van Roosmalen J | 2011-05-05 | BMJ open | |
| Genetic predictors of fibrin D-dimer levels in healthy adults. | Smith NL, Huffman JE, Strachan DP, Huang J, Dehghan A, Trompet S, Lopez LM, Shin SY, Baumert J, Vitart V, Bis JC, Wild SH, Rumley A, Yang Q, Uitterlinden AG, Stott DJ, Davies G, Carter AM, Thorand B, Polašek O, McKnight B, Campbell H, Rudnicka AR, Chen MH, Buckley BM, Harris SE, Peters A, Pulanic D, Lumley T, de Craen AJ, Liewald DC, Gieger C, Campbell S, Ford I, Gow AJ, Luciano M, Porteous DJ, Guo X, Sattar N, Tenesa A, Cushman M, Slagboom PE, Visscher PM, Spector TD, Illig T, Rudan I, Bovill EG, Wright AF, McArdle WL, Tofler G, Hofman A, Westendorp RG, Starr JM, Grant PJ, Karakas M, Hastie ND, Psaty BM, Wilson JF, Lowe GD, O'Donnell CJ, Witteman JC, Jukema JW, Deary IJ, Soranzo N, Koenig W, Hayward C | 2011-05-03 | Circulation | |
| Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study. | Panoutsopoulou K, Southam L, Elliott KS, Wrayner N, Zhai G, Beazley C, Thorleifsson G, Arden NK, Carr A, Chapman K, Deloukas P, Doherty M, McCaskie A, Ollier WE, Ralston SH, Spector TD, Valdes AM, Wallis GA, Wilkinson JM, Arden E, Battley K, Blackburn H, Blanco FJ, Bumpstead S, Cupples LA, Day-Williams AG, Dixon K, Doherty SA, Esko T, Evangelou E, Felson D, Gomez-Reino JJ, Gonzalez A, Gordon A, Gwilliam R, Halldorsson BV, Hauksson VB, Hofman A, Hunt SE, Ioannidis JP, Ingvarsson T, Jonsdottir I, Jonsson H, Keen R, Kerkhof HJ, Kloppenburg MG, Koller N, Lakenberg N, Lane NE, Lee AT, Metspalu A, Meulenbelt I, Nevitt MC, O'Neill F, Parimi N, Potter SC, Rego-Perez I, Riancho JA, Sherburn K, Slagboom PE, Stefansson K, Styrkarsdottir U, Sumillera M, Swift D, Thorsteinsdottir U, Tsezou A, Uitterlinden AG, van Meurs JB, Watkins B, Wheeler M, Mitchell S, Zhu Y, Zmuda JM, Zeggini E, Loughlin J | 2011-05-01 | Annals of the rheumatic diseases | |
| Osteoarthritis susceptibility genes influence the association between hip morphology and osteoarthritis. | Waarsing JH, Kloppenburg M, Slagboom PE, Kroon HM, Houwing-Duistermaat JJ, Weinans H, Meulenbelt I | 2011-05-01 | Arthritis and rheumatism | |
| The effect of cognitive impairment on the predictive value of multimorbidity for the increase in disability in the oldest old: the Leiden 85-plus Study. | Drewes YM, den Elzen WP, Mooijaart SP, de Craen AJ, Assendelft WJ, Gussekloo J | 2011-05-01 | Age and ageing | |
| Plasma protein N-glycan profiles are associated with calendar age, familial longevity and health. | Ruhaak LR, Uh HW, Beekman M, Hokke CH, Westendorp RG, Houwing-Duistermaat J, Wuhrer M, Deelder AM, Slagboom PE | 2011-04-01 | Journal of proteome research | |
| Effects of medication review on drug-related problems in patients using automated drug-dispensing systems: a pragmatic randomized controlled study. | Kwint HF, Faber A, Gussekloo J, Bouvy ML | 2011-04-01 | Drugs & aging | |
| The implementation of the serial trial intervention for pain and challenging behaviour in advanced dementia patients (STA OP!): a clustered randomized controlled trial. | Pieper MJ, Achterberg WP, Francke AL, van der Steen JT, Scherder EJ, Kovach CR | 2011-03-24 | BMC geriatrics | |
| Homocysteine and familial longevity: the Leiden Longevity Study. | Wijsman CA, van Heemst D, Rozing MP, Slagboom PE, Beekman M, de Craen AJ, Maier AB, Westendorp RG, Blom HJ, Mooijaart SP | 2011-03-08 | PloS one | |
| Variation in the CBP gene involved in epigenetic control associates with cognitive function. | Trompet S, de Craen AJ, Jukema JW, Pons D, Slagboom PE, Kremer D, Bollen EL, Westendorp RG | 2011-03-01 | Neurobiology of aging | |
| Association study in eating disorders: TPH2 associates with anorexia nervosa and self-induced vomiting. | Slof-Op 't Landt MC, Meulenbelt I, Bartels M, Suchiman E, Middeldorp CM, Houwing-Duistermaat JJ, van Trier J, Onkenhout EJ, Vink JM, van Beijsterveldt CE, Brandys MK, Sanders N, Zipfel S, Herzog W, Herpertz-Dahlmann B, Klampfl K, Fleischhaker C, Zeeck A, de Zwaan M, Herpertz S, Ehrlich S, van Elburg AA, Adan RA, Scherag S, Hinney A, Hebebrand J, Boomsma DI, van Furth EF, Slagboom PE | 2011-03-01 | Genes, brain, and behavior | |
| Can non-monetary incentives increase health facility deliveries? The experience in Thyolo District, Malawi. | van den Akker T, Radge G, Mateyu A, Mwagomba B, Bemelmans M, Reid T | 2011-03-01 | International health | |
| Yield and costs of direct and stepped screening for depressive symptoms in subjects aged 75 years and over in general practice. | van der Weele GM, de Waal MW, van den Hout WB, van der Mast RC, de Craen AJ, Assendelft WJ, Gussekloo J | 2011-03-01 | International journal of geriatric psychiatry | |
| Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). | Freeman DJ, Robertson M, Brown EA, Rumley A, Tobias ES, Frölich M, Slagboom PE, Jukema JW, de Craen AJ, Sattar N, Ford I, Gaw A, Greer IA, Lowe GD, Stott DJ | 2011-02-22 | BMC geriatrics | |
| DNA methylation of IGF2, GNASAS, INSIGF and LEP and being born small for gestational age. | Tobi EW, Heijmans BT, Kremer D, Putter H, Delemarre-van de Waal HA, Finken MJ, Wit JM, Slagboom PE | 2011-02-01 | Epigenetics | |
| Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. | Evangelou E, Valdes AM, Kerkhof HJ, Styrkarsdottir U, Zhu Y, Meulenbelt I, Lories RJ, Karassa FB, Tylzanowski P, Bos SD, Akune T, Arden NK, Carr A, Chapman K, Cupples LA, Dai J, Deloukas P, Doherty M, Doherty S, Engstrom G, Gonzalez A, Halldorsson BV, Hammond CL, Hart DJ, Helgadottir H, Hofman A, Ikegawa S, Ingvarsson T, Jiang Q, Jonsson H, Kaprio J, Kawaguchi H, Kisand K, Kloppenburg M, Kujala UM, Lohmander LS, Loughlin J, Luyten FP, Mabuchi A, McCaskie A, Nakajima M, Nilsson PM, Nishida N, Ollier WE, Panoutsopoulou K, van de Putte T, Ralston SH, Rivadeneira F, Saarela J, Schulte-Merker S, Shi D, Slagboom PE, Sudo A, Tamm A, Tamm A, Thorleifsson G, Thorsteinsdottir U, Tsezou A, Wallis GA, Wilkinson JM, Yoshimura N, Zeggini E, Zhai G, Zhang F, Jonsdottir I, Uitterlinden AG, Felson DT, van Meurs JB, Stefansson K, Ioannidis JP, Spector TD | 2011-02-01 | Annals of the rheumatic diseases | |
| Familial longevity is marked by enhanced insulin sensitivity. | Wijsman CA, Rozing MP, Streefland TC, le Cessie S, Mooijaart SP, Slagboom PE, Westendorp RG, Pijl H, van Heemst D | 2011-02-01 | Aging cell | |
| Accelerated cognitive decline in patients with type 2 diabetes: MRI correlates and risk factors. | Reijmer YD, van den Berg E, de Bresser J, Kessels RP, Kappelle LJ, Algra A, Biessels GJ | 2011-02-01 | Diabetes/metabolism research and reviews | |
| Family perceptions of wishes of dementia patients regarding end-of-life care. | Van Der Steen JT, Van Soest-Poortvliet MC, Achterberg WP, Ribbe MW, De Vet HC | 2011-02-01 | International journal of geriatric psychiatry | |
| A comparison of MR based segmentation methods for measuring brain atrophy progression. | de Bresser J, Portegies MP, Leemans A, Biessels GJ, Kappelle LJ, Viergever MA | 2011-01-15 | NeuroImage | |
| Genomics of human longevity. | Slagboom PE, Beekman M, Passtoors WM, Deelen J, Vaarhorst AA, Boer JM, van den Akker EB, van Heemst D, de Craen AJ, Maier AB, Rozing M, Mooijaart SP, Heijmans BT, Westendorp RG | 2011-01-12 | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | |
| Keeping health staff healthy: evaluation of a workplace initiative to reduce morbidity and mortality from HIV/AIDS in Malawi. | Bemelmans M, van den Akker T, Pasulani O, Tayub NS, Hermann K, Mwagomba B, Jalasi W, Chiomba H, Ford N, Philips M | 2011-01-05 | Journal of the International AIDS Society | |
| Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility. | Meulenbelt I, Bos SD, Chapman K, van der Breggen R, Houwing-Duistermaat JJ, Kremer D, Kloppenburg M, Carr A, Tsezou A, González A, Loughlin J, Slagboom PE | 2011-01-01 | Annals of the rheumatic diseases | |
| Influence of candidate genes on attention problems in children: a longitudinal study. | van Beijsterveldt CE, Middeldorp CM, Slof-Op't Landt MC, Bartels M, Hottenga JJ, Suchiman HE, Slagboom PE, Boomsma DI | 2011-01-01 | Behavior genetics | |
| Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies. | Pons D, Trompet S, de Craen AJ, Thijssen PE, Quax PH, de Vries MR, Wierda RJ, van den Elsen PJ, Monraats PS, Ewing MM, Heijmans BT, Slagboom PE, Zwinderman AH, Doevendans PA, Tio RA, de Winter RJ, de Maat MP, Iakoubova OA, Sattar N, Shepherd J, Westendorp RG, Jukema JW | 2011-01-01 | Heart (British Cardiac Society) | |
| Factor VII Activating Protease Polymorphism (G534E) Is Associated with Increased Risk for Stroke and Mortality. | Trompet S, Pons D, Kanse SM, de Craen AJ, Ikram MA, Verschuren JJ, Zwinderman AH, Doevendans PA, Tio RA, de Winter RJ, Slagboom PE, Westendorp RG, Jukema JW | 2011-01-01 | Stroke research and treatment | |
| Association between several clinical and radiological determinants with long-term clinical progression and good prognosis of lower limb osteoarthritis. | Yusuf E, Bijsterbosch J, Slagboom PE, Kroon HM, Rosendaal FR, Huizinga TW, Kloppenburg M | 2011-01-01 | PloS one | |
| Relation between maximum replicative capacity and oxidative stress-induced responses in human skin fibroblasts in vitro. | Dekker P, de Lange MJ, Dirks RW, van Heemst D, Tanke HJ, Westendorp RG, Maier AB | 2011-01-01 | The journals of gerontology. Series A, Biological sciences and medical sciences | |
| Reduction of severe acute maternal morbidity and maternal mortality in Thyolo District, Malawi: the impact of obstetric audit. | van den Akker T, van Rhenen J, Mwagomba B, Lommerse K, Vinkhumbo S, van Roosmalen J | 2011-01-01 | PloS one | |
| Polymorphisms associated with type 2 diabetes in familial longevity: The Leiden Longevity Study. | Mooijaart SP, van Heemst D, Noordam R, Rozing MP, Wijsman CA, de Craen AJ, Westendorp RG, Beekman M, Slagboom PE | 2011-01-01 | Aging | |
| C-reactive protein and genetic variants and cognitive decline in old age: the PROSPER study. | Mooijaart SP, Sattar N, Trompet S, Polisecki E, de Craen AJ, Schaefer EJ, Jahn SE, van Himbergen T, Welsh P, Ford I, Stott DJ, Westendorp RG | 2011-01-01 | PloS one | |
| Determinants of absence of osteoarthritis in old age. | Goekoop RJ, Kloppenburg M, Kroon HM, Dirkse LE, Huizinga TW, Westendorp RG, Gussekloo J | 2011-01-01 | Scandinavian journal of rheumatology | |
| Cerebral cortical thickness in patients with type 2 diabetes. | Brundel M, van den Heuvel M, de Bresser J, Kappelle LJ, Biessels GJ | 2010-12-15 | Journal of the neurological sciences | |
| Effect of erythropoietin levels on mortality in old age: the Leiden 85-plus Study. | den Elzen WP, Willems JM, Westendorp RG, de Craen AJ, Blauw GJ, Ferrucci L, Assendelft WJ, Gussekloo J | 2010-12-14 | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne | |
| The serotonin transporter gene length polymorphism (5-HTTLPR) and life events: no evidence for an interaction effect on neuroticism and anxious depressive symptoms. | Middeldorp CM, de Geus EJ, Willemsen G, Hottenga JJ, Slagboom PE, Boomsma DI | 2010-12-01 | Twin research and human genetics : the official journal of the International Society for Twin Studies | |
| Providing universal access to antiretroviral therapy in Thyolo, Malawi through task shifting and decentralization of HIV/AIDS care. | Bemelmans M, van den Akker T, Ford N, Philips M, Zachariah R, Harries A, Schouten E, Hermann K, Mwagomba B, Massaquoi M | 2010-12-01 | Tropical medicine & international health : TM & IH | |
| Chronic kidney disease in patients with diabetes mellitus type 2 or hypertension in general practice. | van der Meer V, Wielders HP, Grootendorst DC, de Kanter JS, Sijpkens YW, Assendelft WJ, Gussekloo J, Dekker FW, Groeneveld Y | 2010-12-01 | The British journal of general practice : the journal of the Royal College of General Practitioners | |
| Diagnostic accuracy of plasma NT-proBNP levels for excluding cardiac abnormalities in the very elderly. | Vaes B, Delgado V, Bax J, Degryse J, Westendorp RG, Gussekloo J | 2010-11-11 | BMC geriatrics | |
| Allele-sharing statistics using information on family history. | Callegaro A, Meulenbelt I, Kloppenburg M, Slagboom PE, Houwing-Duistermaat JJ | 2010-11-01 | Annals of human genetics | |
| Familial longevity is associated with decreased thyroid function. | Rozing MP, Houwing-Duistermaat JJ, Slagboom PE, Beekman M, Frölich M, de Craen AJ, Westendorp RG, van Heemst D | 2010-11-01 | The Journal of clinical endocrinology and metabolism | |
| Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity. | Beekman M, Nederstigt C, Suchiman HE, Kremer D, van der Breggen R, Lakenberg N, Alemayehu WG, de Craen AJ, Westendorp RG, Boomsma DI, de Geus EJ, Houwing-Duistermaat JJ, Heijmans BT, Slagboom PE | 2010-10-19 | Proceedings of the National Academy of Sciences of the United States of America | |
| Cryotherapy with liquid nitrogen versus topical salicylic acid application for cutaneous warts in primary care: randomized controlled trial. | Bruggink SC, Gussekloo J, Berger MY, Zaaijer K, Assendelft WJ, de Waal MW, Bavinck JN, Koes BW, Eekhof JA | 2010-10-19 | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne | |
| Hallmark features of immunosenescence are absent in familial longevity. | Derhovanessian E, Maier AB, Beck R, Jahn G, Hähnel K, Slagboom PE, de Craen AJ, Westendorp RG, Pawelec G | 2010-10-15 | Journal of immunology (Baltimore, Md. : 1950) | |
| Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes? | Middeldorp CM, Slof-Op 't Landt MC, Medland SE, van Beijsterveldt CE, Bartels M, Willemsen G, Hottenga JJ, de Geus EJ, Suchiman HE, Dolan CV, Neale MC, Slagboom PE, Boomsma DI | 2010-10-01 | Genes, brain, and behavior | |
| Insulin, IGF-1 and longevity. | van Heemst D | 2010-10-01 | IGF-1, Insulin, longevity, signaling | Aging and disease |
| Current choices in the treatment of cutaneous warts: a survey among Dutch GP. | Bruggink SC, Waagmeester SC, Gussekloo J, Assendelft WJ, Eekhof JA | 2010-10-01 | Family practice | |
| Subclinical hypothyroidism and the risk of coronary heart disease and mortality. | Rodondi N, den Elzen WP, Bauer DC, Cappola AR, Razvi S, Walsh JP, Asvold BO, Iervasi G, Imaizumi M, Collet TH, Bremner A, Maisonneuve P, Sgarbi JA, Khaw KT, Vanderpump MP, Newman AB, Cornuz J, Franklyn JA, Westendorp RG, Vittinghoff E, Gussekloo J | 2010-09-22 | JAMA | |
| Decreased levels of bisecting GlcNAc glycoforms of IgG are associated with human longevity. | Ruhaak LR, Uh HW, Beekman M, Koeleman CA, Hokke CH, Westendorp RG, Wuhrer M, Houwing-Duistermaat JJ, Slagboom PE, Deelder AM | 2010-09-07 | PloS one | |
| Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology. | Talens RP, Boomsma DI, Tobi EW, Kremer D, Jukema JW, Willemsen G, Putter H, Slagboom PE, Heijmans BT | 2010-09-01 | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | |
| Cognitive decline precedes late-life longitudinal changes in vascular risk factors. | van Vliet P, Westendorp RG, van Heemst D, de Craen AJ, Oleksik AM | 2010-09-01 | Journal of neurology, neurosurgery, and psychiatry | |
| A genome-wide linkage scan reveals CD53 as an important regulator of innate TNF-alpha levels. | Bos SD, Lakenberg N, van der Breggen R, Houwing-Duistermaat JJ, Kloppenburg M, de Craen AJ, Beekman M, Meulenbelt I, Slagboom PE | 2010-08-01 | European journal of human genetics : EJHG | |
| Doyle Index is a valuable additional pain measure in osteoarthritis. | Bijsterbosch J, Wassenaar MJ, le Cessie S, Slagboom PE, Rosendaal FR, Huizinga TW, Kloppenburg M | 2010-08-01 | Osteoarthritis and cartilage | |
| Predictive value of low ferritin in older persons with anemia with and without inflammation: the Leiden 85-plus Study. | den Elzen WP, Gussekloo J, Willems JM, de Craen AJ, Blauw GJ, Blauw GJ, Assendelft WJ, Westendorp RG | 2010-08-01 | Journal of the American Geriatrics Society | |
| Mechanisms of p53-mediated repression of the human polycystic kidney disease-1 promoter. | van Bodegom D, Roessingh W, Pridjian A, El Dahr SS | 2010-07-01 | Biochimica et biophysica acta | |
| Low innate production of interleukin-1beta and interleukin-6 is associated with the absence of osteoarthritis in old age. | Goekoop RJ, Kloppenburg M, Kroon HM, Frölich M, Huizinga TW, Westendorp RG, Gussekloo J | 2010-07-01 | Osteoarthritis and cartilage | |
| How usual is usual care in pragmatic intervention studies in primary care? An overview of recent trials. | Smelt AF, van der Weele GM, Blom JW, Gussekloo J, Assendelft WJ | 2010-07-01 | The British journal of general practice : the journal of the Royal College of General Practitioners | |
| Subnormal vitamin B12 concentrations and anaemia in older people: a systematic review. | den Elzen WP, van der Weele GM, Gussekloo J, Westendorp RG, Assendelft WJ | 2010-06-23 | BMC geriatrics | |
| The Netherlands Twin Register biobank: a resource for genetic epidemiological studies. | Willemsen G, de Geus EJ, Bartels M, van Beijsterveldt CE, Brooks AI, Estourgie-van Burk GF, Fugman DA, Hoekstra C, Hottenga JJ, Kluft K, Meijer P, Montgomery GW, Rizzu P, Sondervan D, Smit AB, Spijker S, Suchiman HE, Tischfield JA, Lehner T, Slagboom PE, Boomsma DI | 2010-06-01 | Twin research and human genetics : the official journal of the International Society for Twin Studies | |
| Progression of cerebral atrophy and white matter hyperintensities in patients with type 2 diabetes. | de Bresser J, Tiehuis AM, van den Berg E, Reijmer YD, Jongen C, Kappelle LJ, Mali WP, Viergever MA, Biessels GJ | 2010-06-01 | Diabetes care | |
| A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. | Newman AB, Walter S, Lunetta KL, Garcia ME, Slagboom PE, Christensen K, Arnold AM, Aspelund T, Aulchenko YS, Benjamin EJ, Christiansen L, D'Agostino RB, Fitzpatrick AL, Franceschini N, Glazer NL, Gudnason V, Hofman A, Kaplan R, Karasik D, Kelly-Hayes M, Kiel DP, Launer LJ, Marciante KD, Massaro JM, Miljkovic I, Nalls MA, Hernandez D, Psaty BM, Rivadeneira F, Rotter J, Seshadri S, Smith AV, Taylor KD, Tiemeier H, Uh HW, Uitterlinden AG, Vaupel JW, Walston J, Westendorp RG, Harris TB, Lumley T, van Duijn CM, Murabito JM | 2010-05-01 | The journals of gerontology. Series A, Biological sciences and medical sciences | |
| Dynamics of traditional metabolic risk factors associate with specific causes of death in old age. | van Vliet P, Oleksik AM, van Heemst D, de Craen AJ, Westendorp RG | 2010-05-01 | The journals of gerontology. Series A, Biological sciences and medical sciences | |
| Unacceptable attrition among WHO stages 1 and 2 patients in a hospital-based setting in rural Malawi: can we retain such patients within the general health system? | Tayler-Smith K, Zachariah R, Massaquoi M, Manzi M, Pasulani O, van den Akker T, Bemelmans M, Bauernfeind A, Mwagomba B, Harries AD | 2010-05-01 | Transactions of the Royal Society of Tropical Medicine and Hygiene | |
| Handgrip strength as a predictor of functional, psychological and social health. A prospective population-based study among the oldest old. | Taekema DG, Gussekloo J, Maier AB, Westendorp RG, de Craen AJ | 2010-05-01 | Age and ageing | |
| Evaluation of a novel broad-spectrum PCR-multiplex genotyping assay for identification of cutaneous wart-associated human papillomavirus types. | de Koning MN, ter Schegget J, Eekhof JA, Kamp M, Kleter B, Gussekloo J, Feltkamp MC, Bouwes Bavinck JN, Purdie KJ, Bunker CB, Proby CM, Meys R, Harwood CA, Quint WG | 2010-05-01 | Journal of clinical microbiology | |
| Interleukin-1 gene cluster variants with innate cytokine production profiles and osteoarthritis in subjects from the Genetics, Osteoarthritis and Progression Study. | Meulenbelt I, Bos SD, Kloppenburg M, Lakenberg N, Houwing-Duistermaat JJ, Watt I, de Craen AJ, van Duijn CM, Slagboom PE | 2010-04-01 | Arthritis and rheumatism | |
| Polymorphisms in TLR4 and TLR2 genes, cytokine production and survival in rural Ghana. | May L, van Bodegom D, Frölich M, van Lieshout L, Slagboom PE, Westendorp RG, Kuningas M | 2010-04-01 | European journal of human genetics : EJHG | |
| Low serum free triiodothyronine levels mark familial longevity: the Leiden Longevity Study. | Rozing MP, Westendorp RG, de Craen AJ, Frölich M, Heijmans BT, Beekman M, Wijsman C, Mooijaart SP, Blauw GJ, Slagboom PE, van Heemst D | 2010-04-01 | The journals of gerontology. Series A, Biological sciences and medical sciences | |
| Impact of valvular heart disease on activities of daily living of nonagenarians: the Leiden 85-plus study a population based study. | van Bemmel T, Delgado V, Bax JJ, Gussekloo J, Blauw GJ, Westendorp RG, Holman ER | 2010-04-01 | BMC geriatrics | |
| Handgrip strength and mortality in the oldest old population: the Leiden 85-plus study. | Ling CH, Taekema D, de Craen AJ, Gussekloo J, Westendorp RG, Maier AB | 2010-03-23 | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne | |
| White blood. | Lommerse K, Mwagomba B, van den Akker T | 2010-03-06 | Lancet (London, England) | |
| Favorable glucose tolerance and lower prevalence of metabolic syndrome in offspring without diabetes mellitus of nonagenarian siblings: the Leiden longevity study. | Rozing MP, Westendorp RG, de Craen AJ, Frölich M, de Goeij MC, Heijmans BT, Beekman M, Wijsman CA, Mooijaart SP, Blauw GJ, Slagboom PE, van Heemst D | 2010-03-01 | Journal of the American Geriatrics Society | |
| Interleukin-1 region meta-analysis with osteoarthritis phenotypes. | Moxley G, Meulenbelt I, Chapman K, van Diujn CM, Slagboom PE, Neale MC, Smith AJ, Carr AJ, Loughlin J | 2010-02-01 | Osteoarthritis and cartilage | |
| Genetic variation in pentraxin (PTX) 3 gene associates with PTX3 production and fertility in women. | May L, Kuningas M, van Bodegom D, Meij HJ, Frolich M, Slagboom PE, Mantovani A, Westendorp RG | 2010-02-01 | Biology of reproduction | |
| Common CFTR gene variants influence body composition and survival in rural Ghana. | Kuningas M, van Bodegom D, May L, Meij JJ, Slagboom PE, Westendorp RG | 2010-02-01 | Human genetics | |
| Breast MRI in clinically and mammographically occult breast cancer presenting with an axillary metastasis: a systematic review. | de Bresser J, de Vos B, van der Ent F, Hulsewé K | 2010-02-01 | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology | |
| Combined risk allele score of eight type 2 diabetes genes is associated with reduced first-phase glucose-stimulated insulin secretion during hyperglycemic clamps. | 't Hart LM, Simonis-Bik AM, Nijpels G, van Haeften TW, Schäfer SA, Houwing-Duistermaat JJ, Boomsma DI, Groenewoud MJ, Reiling E, van Hove EC, Diamant M, Kramer MH, Heine RJ, Maassen JA, Kirchhoff K, Machicao F, Häring HU, Slagboom PE, Willemsen G, Eekhoff EM, de Geus EJ, Dekker JM, Fritsche A | 2010-01-01 | Diabetes | |
| Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B affect different aspects of pancreatic beta-cell function. | Simonis-Bik AM, Nijpels G, van Haeften TW, Houwing-Duistermaat JJ, Boomsma DI, Reiling E, van Hove EC, Diamant M, Kramer MH, Heine RJ, Maassen JA, Slagboom PE, Willemsen G, Dekker JM, Eekhoff EM, de Geus EJ, 't Hart LM | 2010-01-01 | Diabetes | |
| Genetic association analysis of LARS2 with type 2 diabetes. | Reiling E, Jafar-Mohammadi B, van 't Riet E, Weedon MN, van Vliet-Ostaptchouk JV, Hansen T, Saxena R, van Haeften TW, Arp PA, Das S, Nijpels G, Groenewoud MJ, van Hove EC, Uitterlinden AG, Smit JW, Morris AD, Doney AS, Palmer CN, Guiducci C, Hattersley AT, Frayling TM, Pedersen O, Slagboom PE, Altshuler DM, Groop L, Romijn JA, Maassen JA, Hofker MH, Dekker JM, McCarthy MI, 't Hart LM | 2010-01-01 | Diabetologia | |
| When grandmothers matter. | van Bodegom D, Rozing M, May L, Kuningas M, Thomese F, Meij H, Westendorp R | 2010-01-01 | Gerontology | |
| Time trends in preventive drug treatment after myocardial infarction in older patients. | de Ruijter W, de Waal MW, Gussekloo J, Assendelft WJ, Blom JW | 2010-01-01 | The British journal of general practice : the journal of the Royal College of General Practitioners | |
| A 4 year follow-up study of cognitive functioning in patients with type 2 diabetes mellitus. | van den Berg E, Reijmer YD, de Bresser J, Kessels RP, Kappelle LJ, Biessels GJ | 2010-01-01 | Diabetologia | |
| Microvascular determinants of cognitive decline and brain volume change in elderly patients with type 2 diabetes. | de Bresser J, Reijmer YD, van den Berg E, Breedijk MA, Kappelle LJ, Viergever MA, Biessels GJ | 2010-01-01 | Dementia and geriatric cognitive disorders | |
| Pain in European long-term care facilities: cross-national study in Finland, Italy and The Netherlands. | Achterberg WP, Gambassi G, Finne-Soveri H, Liperoti R, Noro A, Frijters DHM, Cherubini A, Dell'Aquila G, Ribbe MW | 2010-01-01 | Pain | |
| Sex differences in sum scores may be hard to interpret: the importance of measurement invariance. | Slof-Op 't Landt MC, Dolan CV, Rebollo-Mesa I, Bartels M, van Furth EF, van Beijsterveldt CE, Meulenbelt I, Slagboom PE, Boomsma DI | 2009-12-01 | Assessment | |
| Using audits to reduce the incidence of uterine rupture in a Malawian district hospital. | van den Akker T, Mwagomba B, Irlam J, van Roosmalen J | 2009-12-01 | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics | |
| The epigenome: archive of the prenatal environment. | Heijmans BT, Tobi EW, Lumey LH, Slagboom PE | 2009-11-16 | Epigenetics | |
| Periconceptional maternal folic acid use of 400 microg per day is related to increased methylation of the IGF2 gene in the very young child. | Steegers-Theunissen RP, Obermann-Borst SA, Kremer D, Lindemans J, Siebel C, Steegers EA, Slagboom PE, Heijmans BT | 2009-11-16 | PloS one | |
| Selection for genetic variation inducing pro-inflammatory responses under adverse environmental conditions in a Ghanaian population. | Kuningas M, May L, Tamm R, van Bodegom D, van den Biggelaar AH, Meij JJ, Frölich M, Ziem JB, Suchiman HE, Metspalu A, Slagboom PE, Westendorp RG | 2009-11-11 | PloS one | |
| DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific. | Tobi EW, Lumey LH, Talens RP, Kremer D, Putter H, Stein AD, Slagboom PE, Heijmans BT | 2009-11-01 | Human molecular genetics | |
| Multicenter dizygotic twin cohort study confirms two linkage susceptibility loci for body mass index at 3q29 and 7q36 and identifies three further potential novel loci. | Kettunen J, Perola M, Martin NG, Cornes BK, Wilson SG, Montgomery GW, Benyamin B, Harris JR, Boomsma D, Willemsen G, Hottenga JJ, Slagboom PE, Christensen K, Kyvik KO, Sørensen TI, Pedersen NL, Magnusson PK, Andrew T, Spector TD, Widen E, Silventoinen K, Kaprio J, Palotie A, Peltonen L | 2009-11-01 | International journal of obesity (2005) | |
| Rapid flow cytometric method for measuring senescence associated beta-galactosidase activity in human fibroblasts. | Noppe G, Dekker P, de Koning-Treurniet C, Blom J, van Heemst D, Dirks RW, Tanke HJ, Westendorp RG, Maier AB | 2009-11-01 | Cytometry. Part A : the journal of the International Society for Analytical Cytology | |
| The accuracy of plasma natriuretic peptide levels for diagnosis of cardiac dysfunction and chronic heart failure in community-dwelling elderly: a systematic review. | Vaes B, de Ruijter W, Gussekloo J, Degryse J | 2009-11-01 | Age and ageing | |
| Stress-induced responses of human skin fibroblasts in vitro reflect human longevity. | Dekker P, Maier AB, van Heemst D, de Koning-Treurniet C, Blom J, Dirks RW, Tanke HJ, Westendorp RG | 2009-09-01 | Aging cell | |
| Biology of cancer and ageing. | van Heemst D | 2009-09-01 | European journal of cancer (Oxford, England : 1990) | |
| Nonagenarian siblings and their offspring display lower risk of mortality and morbidity than sporadic nonagenarians: The Leiden Longevity Study. | Westendorp RG, van Heemst D, Rozing MP, Frölich M, Mooijaart SP, Blauw GJ, Beekman M, Heijmans BT, de Craen AJ, Slagboom PE | 2009-09-01 | Journal of the American Geriatrics Society | |
| Effect of anemia and comorbidity on functional status and mortality in old age: results from the Leiden 85-plus Study. | den Elzen WP, Willems JM, Westendorp RG, de Craen AJ, Assendelft WJ, Gussekloo J | 2009-08-04 | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne | |
| Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study. | Reiling E, van Vliet-Ostaptchouk JV, van 't Riet E, van Haeften TW, Arp PA, Hansen T, Kremer D, Groenewoud MJ, van Hove EC, Romijn JA, Smit JW, Nijpels G, Heine RJ, Uitterlinden AG, Pedersen O, Slagboom PE, Maassen JA, Hofker MH, 't Hart LM, Dekker JM | 2009-08-01 | European journal of human genetics : EJHG | |
| Socio-economic status by rapid appraisal is highly correlated with mortality risks in rural Africa. | van Bodegom D, May L, Kuningas M, Kaptijn R, Thomése F, Meij HJ, Amankwa J, Westendorp RG | 2009-08-01 | Transactions of the Royal Society of Tropical Medicine and Hygiene | |
| Human insulin/IGF-1 and familial longevity at middle age. | Rozing MP, Westendorp RG, Frölich M, de Craen AJ, Beekman M, Heijmans BT, Mooijaart SP, Blauw GJ, Slagboom PE, van Heemst D | 2009-07-24 | IGF-1, IGFBP3, familial longevity, glucose handling, height | Aging |
| Warts in primary schoolchildren: prevalence and relation with environmental factors. | van Haalen FM, Bruggink SC, Gussekloo J, Assendelft WJ, Eekhof JA | 2009-07-01 | The British journal of dermatology | |
| The effect of age on the association between blood pressure and cognitive function later in life. | Euser SM, van Bemmel T, Schram MT, Gussekloo J, Hofman A, Westendorp RG, Breteler MM | 2009-07-01 | Journal of the American Geriatrics Society | |
| Construction of periventricular white matter hyperintensity maps by spatial normalization of the lateral ventricles. | Jongen C, van der Grond J, Anbeek P, Viergever MA, Biessels GJ, Pluim JP | 2009-07-01 | Human brain mapping | |
| Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand. | Evangelou E, Chapman K, Meulenbelt I, Karassa FB, Loughlin J, Carr A, Doherty M, Doherty S, Gómez-Reino JJ, Gonzalez A, Halldorsson BV, Hauksson VB, Hofman A, Hart DJ, Ikegawa S, Ingvarsson T, Jiang Q, Jonsdottir I, Jonsson H, Kerkhof HJ, Kloppenburg M, Lane NE, Li J, Lories RJ, van Meurs JB, Näkki A, Nevitt MC, Rodriguez-Lopez J, Shi D, Slagboom PE, Stefansson K, Tsezou A, Wallis GA, Watson CM, Spector TD, Uitterlinden AG, Valdes AM, Ioannidis JP | 2009-06-01 | Arthritis and rheumatism | |
| A genome wide association analysis in the GENDER study. | Sampietro ML, Pons D, de Knijff P, Slagboom PE, Zwinderman A, Jukema JW | 2009-06-01 | Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation | |
| Co-occurrence of depression and anxiety in elderly subjects aged 90 years and its relationship with functional status, quality of life and mortality. | Van der Weele GM, Gussekloo J, De Waal MW, De Craen AJ, Van der Mast RC | 2009-06-01 | International journal of geriatric psychiatry | |
| Adverse environmental conditions influence age-related innate immune responsiveness. | May L, van den Biggelaar AH, van Bodegom D, Meij HJ, de Craen AJ, Amankwa J, Frölich M, Kuningas M, Westendorp RG | 2009-05-30 | Immunity & ageing : I & A | |
| The role of plasma cytokine levels, CRP and Selenoprotein S gene variation in OA. | Bos SD, Kloppenburg M, Suchiman E, van Beelen E, Slagboom PE, Meulenbelt I | 2009-05-01 | Osteoarthritis and cartilage | |
| Quality-quantity trade-off of human offspring under adverse environmental conditions. | Meij JJ, van Bodegom D, Ziem JB, Amankwa J, Polderman AM, Kirkwood TB, de Craen AJ, Zwaan BJ, Westendorp RG | 2009-05-01 | Journal of evolutionary biology | |
| Benefits of increasing the dose of influenza vaccine in residents of long-term care facilities: a randomized placebo-controlled trial. | Cools HJ, Gussekloo J, Remmerswaal JE, Remarque EJ, Kroes AC | 2009-05-01 | Journal of medical virology | |
| Clinical relevance of a raised plasma N-terminal pro-brain natriuretic peptide level in a population-based cohort of nonagenarians. | Vaes B, de Ruijter W, Degryse J, Westendorp RG, Gussekloo J | 2009-05-01 | Journal of the American Geriatrics Society | |
| [Estimation of kidney function in a nursing home]. | Vergeer WJ, Achterberg WP, Wiltink EH, Geers AB, de Vet HC | 2009-04-11 | Nederlands tijdschrift voor geneeskunde | |
| Suggestive linkage on chromosome 2, 8, and 17 for lifetime major depression. | Middeldorp CM, Sullivan PF, Wray NR, Hottenga JJ, de Geus EJ, van den Berg M, Montgomery GW, Coventry WL, Statham DJ, Andrews G, Slagboom PE, Boomsma DI, Martin NG | 2009-04-05 | American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics | |
| APOE genotype modulates the effect of serum calcium levels on cognitive function in old age. | van Vliet P, Oleksik AM, Mooijaart SP, de Craen AJ, Westendorp RG | 2009-03-03 | Neurology | |
| Association of a nsSNP in ADAMTS14 to some osteoarthritis phenotypes. | Rodriguez-Lopez J, Pombo-Suarez M, Loughlin J, Tsezou A, Blanco FJ, Meulenbelt I, Slagboom PE, Valdes AM, Spector TD, Gomez-Reino JJ, Gonzalez A | 2009-03-01 | Osteoarthritis and cartilage | |
| Genome-wide association study of smoking initiation and current smoking. | Vink JM, Smit AB, de Geus EJ, Sullivan P, Willemsen G, Hottenga JJ, Smit JH, Hoogendijk WJ, Zitman FG, Peltonen L, Kaprio J, Pedersen NL, Magnusson PK, Spector TD, Kyvik KO, Morley KI, Heath AC, Martin NG, Westendorp RG, Slagboom PE, Tiemeier H, Hofman A, Uitterlinden AG, Aulchenko YS, Amin N, van Duijn C, Penninx BW, Boomsma DI | 2009-03-01 | American journal of human genetics | |
| Performance of the whole-blood stimulation assay for assessing innate immune activation under field conditions. | May L, van Bodegom D, Kuningas M, Meij JJ, de Craen AJ, Frölich M, Westendorp RG | 2009-03-01 | Cytokine | |
| Association of the autoimmunity locus 4q27 with juvenile idiopathic arthritis. | Albers HM, Kurreeman FA, Stoeken-Rijsbergen G, Brinkman DM, Kamphuis SS, van Rossum MA, Girschick HJ, Wouters C, Saurenmann RK, Hoppenreijs E, Slagboom P, Houwing-Duistermaat JJ, Verduijn W, Huizinga TW, Ten Cate R, Toes RE, Schilham MW | 2009-03-01 | Arthritis and rheumatism | |
| VDR gene variants associate with cognitive function and depressive symptoms in old age. | Kuningas M, Mooijaart SP, Jolles J, Slagboom PE, Westendorp RG, van Heemst D | 2009-03-01 | Neurobiology of aging | |
| Complement factor H Y402H decreases cardiovascular disease risk in patients with familial hypercholesterolaemia. | Koeijvoets KC, Mooijaart SP, Dallinga-Thie GM, Defesche JC, Steyerberg EW, Westendorp RG, Kastelein JJ, van Hagen PM, Sijbrands EJ | 2009-03-01 | European heart journal | |
| Weighted statistics for aggregation and linkage analysis of human longevity in selected families: the Leiden Longevity Study. | Houwing-Duistermaat JJ, Callegaro A, Beekman M, Westendorp RG, Slagboom PE, van Houwelingen JC | 2009-01-15 | Statistics in medicine | |
| Use of Framingham risk score and new biomarkers to predict cardiovascular mortality in older people: population based observational cohort study. | de Ruijter W, Westendorp RG, Assendelft WJ, den Elzen WP, de Craen AJ, le Cessie S, Gussekloo J | 2009-01-08 | BMJ (Clinical research ed.) | |
| Low blood pressure in the very old, a consequence of imminent heart failure: the Leiden 85-plus Study. | van Bemmel T, Holman ER, Gussekloo J, Blauw GJ, Bax JJ, Westendorp RG | 2009-01-01 | Journal of human hypertension | |
| [Disciplinary proceedings on screening and preventive diagnostics]. | Drewes YM, Meesters JP, Gussekloo J, Middelkoop BJ, Hendriks AC | 2009-01-01 | Nederlands tijdschrift voor geneeskunde | |
| Statins and blood pressure. | Trompet S, Jukema JW, Ford I, Shepherd J, Gussekloo J, Buckley BM, Westendorp RG, de Craen AJ | 2008-11-24 | Archives of internal medicine | |
| Vitamin B12 and folate and the risk of anemia in old age: the Leiden 85-Plus Study. | den Elzen WP, Westendorp RG, Frölich M, de Ruijter W, Assendelft WJ, Gussekloo J | 2008-11-10 | Archives of internal medicine | |
| Persistent epigenetic differences associated with prenatal exposure to famine in humans. | Heijmans BT, Tobi EW, Stein AD, Putter H, Blauw GJ, Susser ES, Slagboom PE, Lumey LH | 2008-11-04 | Proceedings of the National Academy of Sciences of the United States of America | |
| Vitamin D receptor gene polymorphisms have negligible effect on human height. | Macgregor S, Hottenga JJ, Lind PA, Suchiman HE, Willemsen G, Slagboom PE, Montgomery GW, Martin NG, Visscher PM, Boomsma DI | 2008-10-01 | Twin research and human genetics : the official journal of the International Society for Twin Studies | |
| [Stroke patients in need of long-term nursing home care. Who are they? What are their problems? Which care do they receive?]. | Smalbrugge M, Achterberg WP, Dik MG, Hertogh CM, Frijters DH | 2008-10-01 | Tijdschrift voor gerontologie en geriatrie | |
| New insights into osteoarthritis: early developmental features of an ageing-related disease. | Bos SD, Slagboom PE, Meulenbelt I | 2008-09-01 | Current opinion in rheumatology | |
| Insulin/Insulin-like growth factor-1 signaling and cognitive function in humans. | Euser SM, van Heemst D, van Vliet P, Breteler MM, Westendorp RG | 2008-09-01 | The journals of gerontology. Series A, Biological sciences and medical sciences | |
| Incidence and predictive factors of lower respiratory tract infections among the very elderly in the general population. The Leiden 85-plus Study. | Sliedrecht A, den Elzen WP, Verheij TJ, Westendorp RG, Gussekloo J | 2008-09-01 | Thorax | |
| Lymphotoxin-alpha C804A polymorphism is a risk factor for stroke. The PROSPER study. | Trompet S, de Craen AJ, Slagboom P, Shepherd J, Blauw GJ, Murphy MB, Bollen EL, Buckley BM, Ford I, Gaw A, Macfarlane PW, Packard CJ, Stott DJ, Westendorp RG, Jukema JW | 2008-08-01 | Experimental gerontology | |
| Colony formation and colony size do not reflect the onset of replicative senescence in human fibroblasts. | Maier AB, Maier IL, van Heemst D, Westendorp RG | 2008-07-01 | The journals of gerontology. Series A, Biological sciences and medical sciences | |
| Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis. | Meulenbelt I, Min JL, Bos S, Riyazi N, Houwing-Duistermaat JJ, van der Wijk HJ, Kroon HM, Nakajima M, Ikegawa S, Uitterlinden AG, van Meurs JB, van der Deure WM, Visser TJ, Seymour AB, Lakenberg N, van der Breggen R, Kremer D, van Duijn CM, Kloppenburg M, Loughlin J, Slagboom PE | 2008-06-15 | Human molecular genetics | |
| Meta-analysis: subclinical thyroid dysfunction and the risk for coronary heart disease and mortality. | Ochs N, Auer R, Bauer DC, Nanchen D, Gussekloo J, Cornuz J, Rodondi N | 2008-06-03 | Annals of internal medicine | |
| Allelic variation at the C-reactive protein gene associates to both hand osteoarthritis severity and serum high sensitive C-reactive protein levels in the GARP study. | Bos SD, Suchiman HE, Kloppenburg M, Houwing-Duistermaat JJ, le Graverand MP, Seymour AB, Kroon HM, Slagboom PE, Meulenbelt I | 2008-06-01 | Annals of the rheumatic diseases | |
| Genome-wide linkage analysis of multiple measures of neuroticism of 2 large cohorts from Australia and the Netherlands. | Wray NR, Middeldorp CM, Birley AJ, Gordon SD, Sullivan PF, Visscher PM, Nyholt DR, Willemsen G, de Geus EJ, Slagboom PE, Montgomery GW, Martin NG, Boomsma DI | 2008-06-01 | Archives of general psychiatry | |
| [Prevalence of ulcers in Dutch nursing homes]. | Achterberg WP, Frijters DH, Ribbe MW | 2008-06-01 | Tijdschrift voor gerontologie en geriatrie | |
| A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5′ UTR of GDF5 with osteoarthritis susceptibility. | Chapman K, Takahashi A, Meulenbelt I, Watson C, Rodriguez-Lopez J, Egli R, Tsezou A, Malizos KN, Kloppenburg M, Shi D, Southam L, van der Breggen R, Donn R, Qin J, Doherty M, Slagboom PE, Wallis G, Kamatani N, Jiang Q, Gonzalez A, Loughlin J, Ikegawa S | 2008-05-15 | Human molecular genetics | |
| Genetic influences on disordered eating behaviour are largely independent of body mass index. | Slof-Op 't Landt MC, Bartels M, van Furth EF, van Beijsterveldt CE, Meulenbelt I, Slagboom PE, Boomsma DI | 2008-05-01 | Acta psychiatrica Scandinavica | |
| Influence of the TP53 codon 72 polymorphism on the cellular responses to X-irradiation in fibroblasts from nonagenarians. | den Reijer PM, Maier AB, Westendorp RG, van Heemst D | 2008-04-01 | Mechanisms of ageing and development | |
| Genetic variation in the interleukin-1 beta-converting enzyme associates with cognitive function. The PROSPER study. | Trompet S, de Craen AJ, Slagboom P, Shepherd J, Blauw GJ, Murphy MB, Bollen EL, Buckley BM, Ford I, Gaw A, Macfarlane PW, Packard CJ, Stott DJ, Jukema JW, Westendorp RG | 2008-04-01 | Brain : a journal of neurology | |
| Long-term use of proton pump inhibitors and vitamin B12 status in elderly individuals. | den Elzen WP, Groeneveld Y, de Ruijter W, Souverijn JH, le Cessie S, Assendelft WJ, Gussekloo J | 2008-03-15 | Alimentary pharmacology & therapeutics | |
| A whole genome association study of neuroticism using DNA pooling. | Shifman S, Bhomra A, Smiley S, Wray NR, James MR, Martin NG, Hettema JM, An SS, Neale MC, van den Oord EJ, Kendler KS, Chen X, Boomsma DI, Middeldorp CM, Hottenga JJ, Slagboom PE, Flint J | 2008-03-01 | Molecular psychiatry | |
| Genes encoding longevity: from model organisms to humans. | Kuningas M, Mooijaart SP, van Heemst D, Zwaan BJ, Slagboom PE, Westendorp RG | 2008-03-01 | Aging cell | |
| Vascular disease and apathy in old age. The Leiden 85-Plus Study. | van der Mast RC, Vinkers DJ, Stek ML, Bek MC, Westendorp RG, Gussekloo J, de Craen AJ | 2008-03-01 | International journal of geriatric psychiatry | |
| Genomic studies in ageing research: the need to integrate genetic and gene expression approaches. | Passtoors WM, Beekman M, Gunn D, Boer JM, Heijmans BT, Westendorp RG, Zwaan BJ, Slagboom PE | 2008-02-01 | Journal of internal medicine | |
| Plasma apolipoprotein CI protects against mortality from infection in old age. | Berbée JF, Mooijaart SP, de Craen AJ, Havekes LM, van Heemst D, Rensen PC, Westendorp RG | 2008-02-01 | The journals of gerontology. Series A, Biological sciences and medical sciences | |
| [Diagnostic image (356). A man with a painfully distended abdomen and a mass on the plain abdominal radiograph]. | van Bodegom D, Kamper AM | 2008-01-12 | Nederlands tijdschrift voor geneeskunde | |
| [Cardiovascular prevention in the over-80 age group is not beneficial]. | de Ruijter W, Gussekloo J | 2008-01-05 | Nederlands tijdschrift voor geneeskunde | |
| Linkage on chromosome 14 in a genome-wide linkage study of a broad anxiety phenotype. | Middeldorp CM, Hottenga JJ, Slagboom PE, Sullivan PF, de Geus EJ, Posthuma D, Willemsen G, Boomsma DI | 2008-01-01 | Molecular psychiatry | |
| Relation between body height and replicative capacity of human fibroblasts in nonagenarians. | Maier AB, van Heemst D, Westendorp RG | 2008-01-01 | The journals of gerontology. Series A, Biological sciences and medical sciences | |
| Reliability of cluster results for different types of time adjustments in complex disease research. | Colas F, Meulenbelt I, Houwing-Duistermaat JJ, Kloppenburg M, Watt I, van Rooden SM, Visser M, Marinus J, van Hilten JJ, Slagboom P, Kok JN | 2008-01-01 | Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference | |
| The additional value of routine electrocardiograms in cardiovascular risk management of older people. | De Ruijter W, Assendelft WJ, Macfarlane PW, Westendorp RG, Gussekloo J | 2008-01-01 | Scandinavian journal of primary health care | |
| The MDS Challenging Behavior Profile for long-term care. | Gerritsen DL, Achterberg WP, Steverink N, Pot AM, Frijters DH, Ribbe MW | 2008-01-01 | Aging & mental health | |
| The 23K variant of the R23K polymorphism in the glucocorticoid receptor gene protects against postnatal growth failure and insulin resistance after preterm birth. | Finken MJ, Meulenbelt I, Dekker FW, Frölich M, Romijn JA, Slagboom PE, Wit JM | 2007-12-01 | The Journal of clinical endocrinology and metabolism | |
| Telomere length predicts survival independent of genetic influences. | Bakaysa SL, Mucci LA, Slagboom PE, Boomsma DI, McClearn GE, Johansson B, Pedersen NL | 2007-12-01 | Aging cell | |
| The clinically meaningful change in physical performance scores in an elderly cohort. | Nieves JW, Li T, Zion M, Gussekloo J, Pahor M, Bernabei R, Simon H, Williams GR, Lapuerta P | 2007-12-01 | Aging clinical and experimental research | |
| The H63D variant in the HFE gene predisposes to arthralgia, chondrocalcinosis and osteoarthritis. | Alizadeh BZ, Njajou OT, Hazes JM, Hofman A, Slagboom PE, Pols HA, van Duijn CM | 2007-11-01 | Annals of the rheumatic diseases | |
| Complement Factor H polymorphism Y402H associates with inflammation, visual acuity, and cardiovascular mortality in the elderly population at large. | Mooijaart SP, Koeijvoets KM, Sijbrands EJ, Daha MR, Westendorp RG | 2007-11-01 | Experimental gerontology | |
| Pain in the nursing home: assessment and treatment on different types of care wards. | Achterberg WP, Pot AM, Scherder EJ, Ribbe MW | 2007-11-01 | Journal of pain and symptom management | |
| Molecular epidemiology, candidate genes versus genome-wide scans. | Slagboom PE, Heijmans BT, Beekman M, Meulenbelt I | 2007-10-01 | Genes & nutrition | |
| Ageing or cancer: a review on the role of caretakers and gatekeepers. | van Heemst D, den Reijer PM, Westendorp RG | 2007-10-01 | European journal of cancer (Oxford, England : 1990) | |
| The metabolic syndrome is associated with decelerated cognitive decline in the oldest old. | van den Berg E, Biessels GJ, de Craen AJ, Gussekloo J, Westendorp RG | 2007-09-04 | Neurology | |
| SIRT1 gene, age-related diseases, and mortality: the Leiden 85-plus study. | Kuningas M, Putters M, Westendorp RG, Slagboom PE, van Heemst D | 2007-09-01 | The journals of gerontology. Series A, Biological sciences and medical sciences | |
| Evidence for the association of the S100beta gene with low cognitive performance and dementia in the elderly. | Lambert JC, Ferreira S, Gussekloo J, Christiansen L, Brysbaert G, Slagboom E, Cottel D, Petit T, Hauw JJ, DeKosky ST, Richard F, Berr C, Lendon C, Kamboh MI, Mann D, Christensen K, Westendorp R, Amouyel P | 2007-09-01 | Molecular psychiatry | |
| High innate production capacity of tumor necrosis factor-alpha and decline of handgrip strength in old age. | Taekema DG, Westendorp RG, Frölich M, Gussekloo J | 2007-09-01 | Mechanisms of ageing and development | |
| Cardiovascular risk factors in cognitively impaired nursing home patients: a relationship with pain? | Achterberg WP, Scherder E, Pot AM, Ribbe MW | 2007-08-01 | European journal of pain (London, England) | |
| [Not Available]. | Frijters DH, Achterberg WP | 2007-08-01 | Tijdschrift voor gerontologie en geriatrie | |
| [The ZZP Questionnaire. Reliability of a new resource utilization measure]. | Frijters DH, Achterberg WP | 2007-08-01 | Tijdschrift voor gerontologie en geriatrie | |
| Mutation analysis of candidate genes within the 2q33.3 linkage area for familial early-onset generalised osteoarthritis. | Min JL, Meulenbelt I, Kloppenburg M, van Duijn CM, Slagboom PE | 2007-07-01 | European journal of human genetics : EJHG | |
| Inflammation and interleukin-1 signaling network contribute to depressive symptoms but not cognitive decline in old age. | van den Biggelaar AH, Gussekloo J, de Craen AJ, Frölich M, Stek ML, van der Mast RC, Westendorp RG | 2007-07-01 | Experimental gerontology | |
| [Combined vision and hearing impairment: in an estimated 30,000-35,000 people aged 55 years or over in The Netherlands]. | Vaal J, Gussekloo J, de Klerk MM, Frijters DH, Evenhuis HM, van Beek AP, van Nispen RM, Smits C, Deeg DJ | 2007-06-30 | Nederlands tijdschrift voor geneeskunde | |
| FCRL3 promoter 169 CC homozygosity is associated with susceptibility to rheumatoid arthritis in Dutch Caucasians. | Thabet MM, Wesoly J, Slagboom PE, Toes RE, Huizinga TW | 2007-06-01 | Annals of the rheumatic diseases | |
| Mental performance in old age dependent on cortisol and genetic variance in the mineralocorticoid and glucocorticoid receptors. | Kuningas M, de Rijk RH, Westendorp RG, Jolles J, Slagboom PE, van Heemst D | 2007-06-01 | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology | |
| The routine electrocardiogram for cardiovascular risk stratification in old age: the Leiden 85-plus study. | de Ruijter W, Westendorp RG, Macfarlane PW, Jukema JW, Assendelft WJ, Gussekloo J | 2007-06-01 | Journal of the American Geriatrics Society | |
| Clusters of biochemical markers are associated with radiographic subtypes of osteoarthritis (OA) in subject with familial OA at multiple sites. The GARP study. | Meulenbelt I, Kloppenburg M, Kroon HM, Houwing-Duistermaat JJ, Garnero P, Hellio-Le Graverand MP, DeGroot J, Slagboom PE | 2007-04-01 | Osteoarthritis and cartilage | |
| Genetics of healthy aging in Europe: the EU-integrated project GEHA (GEnetics of Healthy Aging). | Franceschi C, Bezrukov V, Blanché H, Bolund L, Christensen K, de Benedictis G, Deiana L, Gonos E, Hervonen A, Yang H, Jeune B, Kirkwood TB, Kristensen P, Leon A, Pelicci PG, Peltonen L, Poulain M, Rea IM, Remacle J, Robine JM, Schreiber S, Sikora E, Slagboom PE, Spazzafumo L, Stazi MA, Toussaint O, Vaupel JW | 2007-04-01 | Annals of the New York Academy of Sciences | |
| Beta-galactosidase activity as a biomarker of replicative senescence during the course of human fibroblast cultures. | Maier AB, Westendorp RG, VAN Heemst D | 2007-04-01 | Annals of the New York Academy of Sciences | |
| Regulation of human life histories: the role of the inflammatory host response. | Van Bodegom D, May L, Meij HJ, Westendorp RG | 2007-04-01 | Annals of the New York Academy of Sciences | |
| Genetic variation in the interleukin-10 gene promoter and risk of coronary and cerebrovascular events: the PROSPER study. | Trompet S, Pons D, DE Craen AJ, Slagboom P, Shepherd J, Blauw GJ, Murphy MB, Cobbe SM, Bollen EL, Buckley BM, Ford I, Hyland M, Gaw A, Macfarlane PW, Packard CJ, Norrie J, Perry IJ, Stott DJ, Sweeney BJ, Twomey C, Westendorp RG, Jukema JW | 2007-04-01 | Annals of the New York Academy of Sciences | |
| Liver X receptor alpha associates with human life span. | Mooijaart SP, Kuningas M, Westendorp RG, Houwing-Duistermaat JJ, Slagboom PE, Rensen PC, van Heemst D | 2007-04-01 | The journals of gerontology. Series A, Biological sciences and medical sciences | |
| Plasma levels of apolipoprotein E and risk of stroke in old age. | van Vliet P, Mooijaart SP, de Craen AJ, Rensen PC, van Heemst D, Westendorp RG | 2007-04-01 | Annals of the New York Academy of Sciences | |
| Plasma levels of apolipoprotein E and cognitive function in old age. | Mooijaart SP, van Vliet P, van Heemst D, Rensen PC, Berbée JF, Jolles J, de Craen AJ, Westendorp RG | 2007-04-01 | Annals of the New York Academy of Sciences | |
| Family based association analyses between the serotonin transporter gene polymorphism (5-HTTLPR) and neuroticism, anxiety and depression. | Middeldorp CM, de Geus EJ, Beem AL, Lakenberg N, Hottenga JJ, Slagboom PE, Boomsma DI | 2007-03-01 | Behavior genetics | |
| Heritable rather than age-related environmental and stochastic factors dominate variation in DNA methylation of the human IGF2/H19 locus. | Heijmans BT, Kremer D, Tobi EW, Boomsma DI, Slagboom PE | 2007-03-01 | Human molecular genetics | |
| Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old age. | Kuningas M, Mägi R, Westendorp RG, Slagboom PE, Remm M, van Heemst D | 2007-03-01 | European journal of human genetics : EJHG | |
| Genetic association analysis of RHOB and TXNDC3 in osteoarthritis. | Loughlin J, Meulenbelt I, Min J, Mustafa Z, Sinsheimer JS, Carr A, Slagboom PE | 2007-02-01 | American journal of human genetics | |
| Persistence of high-replicative capacity in cultured fibroblasts from nonagenarians. | Maier AB, le Cessie S, de Koning-Treurniet C, Blom J, Westendorp RG, van Heemst D | 2007-02-01 | Aging cell | |
| Strong linkage on 2q33.3 to familial early-onset generalized osteoarthritis and a consideration of two positional candidate genes. | Meulenbelt I, Min JL, van Duijn CM, Kloppenburg M, Breedveld FC, Slagboom PE | 2006-12-01 | European journal of human genetics : EJHG | |
| Lipoprotein particle profiles mark familial and sporadic human longevity. | Heijmans BT, Beekman M, Houwing-Duistermaat JJ, Cobain MR, Powell J, Blauw GJ, van der Ouderaa F, Westendorp RG, Slagboom PE | 2006-12-01 | PLoS medicine | |
| [The relationship between atherosclerosis, cognitive impairment, and depression in old age]. | Vinkers DJ, van der Mast RC, Stek ML, Westendorp RG, Gussekloo J | 2006-10-21 | Nederlands tijdschrift voor geneeskunde | |
| The polycystic kidney disease-1 gene is a target for p53-mediated transcriptional repression. | Van Bodegom D, Saifudeen Z, Dipp S, Puri S, Magenheimer BS, Calvet JP, El-Dahr SS | 2006-10-20 | The Journal of biological chemistry | |
| The impact of diabetes mellitus on cognitive decline in the oldest of the old: a prospective population-based study. | van den Berg E, de Craen AJ, Biessels GJ, Gussekloo J, Westendorp RG | 2006-09-01 | Diabetologia | |
| Prospective study of the effect of blood pressure on renal function in old age: the Leiden 85-Plus Study. | van Bemmel T, Woittiez K, Blauw GJ, van der Sman-de Beer F, Dekker FW, Westendorp RG, Gussekloo J | 2006-09-01 | Journal of the American Society of Nephrology : JASN | |
| Association of matrilin-3 polymorphisms with spinal disc degeneration and osteoarthritis of the first carpometacarpal joint of the hand. | Min JL, Meulenbelt I, Riyazi N, Kloppenburg M, Houwing-Duistermaat JJ, Seymour AB, van Duijn CM, Slagboom PE | 2006-08-01 | Annals of the rheumatic diseases | |
| High microsatellite and SNP genotyping success rates established in a large number of genomic DNA samples extracted from mouth swabs and genotypes. | Min JL, Lakenberg N, Bakker-Verweij M, Suchiman E, Boomsma DI, Slagboom PE, Meulenbelt I | 2006-08-01 | Twin research and human genetics : the official journal of the International Society for Twin Studies | |
| Genetic variants in the glucocorticoid receptor gene (NR3C1) and cardiovascular disease risk. The Leiden 85-plus Study. | Kuningas M, Mooijaart SP, Slagboom PE, Westendorp RG, van Heemst D | 2006-08-01 | Biogerontology | |
| Butyrylcholinesterase: association with the metabolic syndrome and identification of 2 gene loci affecting activity. | Valle A, O'Connor DT, Taylor P, Zhu G, Montgomery GW, Slagboom PE, Martin NG, Whitfield JB | 2006-06-01 | Clinical chemistry | |
| ApoE plasma levels and risk of cardiovascular mortality in old age. | Mooijaart SP, Berbée JF, van Heemst D, Havekes LM, de Craen AJ, Slagboom PE, Rensen PC, Westendorp RG | 2006-06-01 | PLoS medicine | |
| Assistive devices and community-based services among 85-year-old community-dwelling elderly in The Netherlands: ownership, use, and need for intervention. | de Craen AJ, Westendorp RG, Willems CG, Buskens IC, Gussekloo J | 2006-06-01 | Disability and rehabilitation. Assistive technology | |
| Randomised controlled trial of unsolicited occupational therapy in community-dwelling elderly people: the LOTIS trial. | de Craen AJ, Gussekloo J, Blauw GJ, Willems CG, Westendorp RG | 2006-05-01 | PLoS clinical trials | |
| Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes. | Wessels JA, de Vries-Bouwstra JK, Heijmans BT, Slagboom PE, Goekoop-Ruiterman YP, Allaart CF, Kerstens PJ, van Zeben D, Breedveld FC, Dijkmans BA, Huizinga TW, Guchelaar HJ | 2006-04-01 | Arthritis and rheumatism | |
| Chromosome 4q25, microsomal transfer protein gene, and human longevity: novel data and a meta-analysis of association studies. | Beekman M, Blauw GJ, Houwing-Duistermaat JJ, Brandt BW, Westendorp RG, Slagboom PE | 2006-04-01 | The journals of gerontology. Series A, Biological sciences and medical sciences | |
| Urinary CTX-II levels are associated with radiographic subtypes of osteoarthritis in hip, knee, hand, and facet joints in subject with familial osteoarthritis at multiple sites: the GARP study. | Meulenbelt I, Kloppenburg M, Kroon HM, Houwing-Duistermaat JJ, Garnero P, Hellio Le Graverand MP, Degroot J, Slagboom PE | 2006-03-01 | Annals of the rheumatic diseases | |
| Impact of genetic variations in the WRN gene on age related pathologies and mortality. | Kuningas M, Slagboom PE, Westendorp RG, van Heemst D | 2006-03-01 | Mechanisms of ageing and development | |
| Markers of autonomic tone on a standard ECG are predictive of mortality in old age. | van Bemmel T, Vinkers DJ, Macfarlane PW, Gussekloo J, Westendorp RG | 2006-02-08 | International journal of cardiology | |
| In a population-based prospective study, no association between high blood pressure and mortality after age 85 years. | van Bemmel T, Gussekloo J, Westendorp RG, Blauw GJ | 2006-02-01 | Journal of hypertension | |
| [Thyroid function, activities of daily living and survival in extreme old age: the ‘Leiden 85-plus Study’]. | Gussekloo J, van Exel E, de Craen AJ, Meinders AE, Frölich M, Westendorp RG | 2006-01-14 | Nederlands tijdschrift voor geneeskunde | |
| Evidence of genetic enrichment for exceptional survival using a family approach: the Leiden Longevity Study. | Schoenmaker M, de Craen AJ, de Meijer PH, Beekman M, Blauw GJ, Slagboom PE, Westendorp RG | 2006-01-01 | European journal of human genetics : EJHG | |
| Replicated linkage for eye color on 15q using comparative ratings of sibling pairs. | Posthuma D, Visscher PM, Willemsen G, Zhu G, Martin NG, Slagboom PE, de Geus EJ, Boomsma DI | 2006-01-01 | Behavior genetics | |
| Combined linkage and association analyses of the 124-bp allele of marker D2S2944 with anxiety, depression, neuroticism and major depression. | Beem AL, Geus EJ, Hottenga JJ, Sullivan PF, Willemsen G, Slagboom PE, Boomsma DI | 2006-01-01 | Behavior genetics | |
| Genetic linkage and association analysis for loneliness in Dutch twin and sibling pairs points to a region on chromosome 12q23-24. | Boomsma DI, Cacioppo JT, Slagboom PE, Posthuma D | 2006-01-01 | Behavior genetics | |
| Natural history of depression in the oldest old: population-based prospective study. | Stek ML, Vinkers DJ, Gussekloo J, van der Mast RC, Beekman AT, Westendorp RG | 2006-01-01 | The British journal of psychiatry : the journal of mental science | |
| Telomere length in white blood cells is not associated with morbidity or mortality in the oldest old: a population-based study. | Martin-Ruiz CM, Gussekloo J, van Heemst D, von Zglinicki T, Westendorp RG | 2005-12-01 | Aging cell | |
| Meta-analysis of four new genome scans for lipid parameters and analysis of positional candidates in positive linkage regions. | Heijmans BT, Beekman M, Putter H, Lakenberg N, van der Wijk HJ, Whitfield JB, Posthuma D, Pedersen NL, Martin NG, Boomsma DI, Slagboom PE | 2005-10-01 | European journal of human genetics : EJHG | |
| Eating disorders: from twin studies to candidate genes and beyond. | Slof-Op 't Landt MC, van Furth EF, Meulenbelt I, Slagboom PE, Bartels M, Boomsma DI, Bulik CM | 2005-10-01 | Twin research and human genetics : the official journal of the International Society for Twin Studies | |
| Association between chronic diseases and disability in elderly subjects with low and high income: the Leiden 85-plus Study. | Bootsma-van der Wiel A, de Craen AJ, Van Exel E, Macfarlane PW, Gussekloo J, Westendorp RG | 2005-10-01 | European journal of public health | |
| Homocysteine, vitamin B-12, and folic acid and the risk of cognitive decline in old age: the Leiden 85-Plus study. | Mooijaart SP, Gussekloo J, Frölich M, Jolles J, Stott DJ, Westendorp RG, de Craen AJ | 2005-10-01 | The American journal of clinical nutrition | |
| RUNX1 intronic SNP is not associated with rheumatoid arthritis susceptibility in Dutch Caucasians. | Wesoly J, Toes RE, Slagboom PE, Huizinga TW | 2005-09-01 | Rheumatology (Oxford, England) | |
| Late-onset dementia: structural brain damage and total cerebral blood flow. | Spilt A, Weverling-Rijnsburger AW, Middelkoop HA, van Der Flier WM, Gussekloo J, de Craen AJ, Bollen EL, Blauw GJ, van Buchem MA, Westendorp RG | 2005-09-01 | Radiology | |
| Sensory impairment and cognitive functioning in oldest-old subjects: the Leiden 85+ Study. | Gussekloo J, de Craen AJ, Oduber C, van Boxtel MP, Westendorp RG | 2005-09-01 | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry | |
| A genomewide scan for intelligence identifies quantitative trait loci on 2q and 6p. | Posthuma D, Luciano M, Geus EJ, Wright MJ, Slagboom PE, Montgomery GW, Boomsma DI, Martin NG | 2005-08-01 | American journal of human genetics | |
| C. elegans DAF-12, Nuclear Hormone Receptors and human longevity and disease at old age. | Mooijaart SP, Brandt BW, Baldal EA, Pijpe J, Kuningas M, Beekman M, Zwaan BJ, Slagboom PE, Westendorp RG, van Heemst D | 2005-08-01 | Ageing research reviews | |
| Generalized atherosclerosis, cognitive decline, and depressive symptoms in old age. | Vinkers DJ, Stek ML, van der Mast RC, de Craen AJ, Le Cessie S, Jolles J, Westendorp RG, Gussekloo J | 2005-07-12 | Neurology | |
| Evaluation of continuous summary physical performance scores (CSPPS) in an elderly cohort. | Nieves JW, Zion M, Pahor M, Bernabei R, Gussekloo J, Simon H, Park JS, Li T, Lapuerta P, Williams GR | 2005-06-01 | Aging clinical and experimental research | |
| Evidence for a role of the genomic region of the gene encoding for the alpha1 chain of type IX collagen (COL9A1) in hip osteoarthritis: A population-based study. | Alizadeh BZ, Njajou OT, Bijkerk C, Meulenbelt I, Wildt SC, Hofman A, Pols HA, Slagboom PE, Duijn CM | 2005-05-01 | Arthritis and rheumatism | |
| Association of the Frizzled-related protein gene with symptomatic osteoarthritis at multiple sites. | Min JL, Meulenbelt I, Riyazi N, Kloppenburg M, Houwing-Duistermaat JJ, Seymour AB, Pols HA, van Duijn CM, Slagboom PE | 2005-04-01 | Arthritis and rheumatism | |
| Human cytokine response to ex vivo amyloid-beta stimulation is mediated by genetic factors. | Posthuma D, Meulenbelt I, de Craen AJ, de Geus EJ, Slagboom PE, Boomsma DI, Westendorp RG | 2005-04-01 | Twin research and human genetics : the official journal of the International Society for Twin Studies | |
| Reduced insulin/IGF-1 signalling and human longevity. | van Heemst D, Beekman M, Mooijaart SP, Heijmans BT, Brandt BW, Zwaan BJ, Slagboom PE, Westendorp RG | 2005-04-01 | Aging cell | |
| Evidence for familial aggregation of hand, hip, and spine but not knee osteoarthritis in siblings with multiple joint involvement: the GARP study. | Riyazi N, Meulenbelt I, Kroon HM, Ronday KH, Hellio le Graverand MP, Rosendaal FR, Breedveld FC, Slagboom PE, Kloppenburg M | 2005-03-01 | Annals of the rheumatic diseases | |
| Shuttling between species for pathways of lifespan regulation: a central role for the vitellogenin gene family? | Brandt BW, Zwaan BJ, Beekman M, Westendorp RG, Slagboom PE | 2005-03-01 | BioEssays : news and reviews in molecular, cellular and developmental biology | |
| Seasonal mood variation in the elderly: the Leiden 85-plus study. | de Craen AJ, Gussekloo J, van der Mast RC, le Cessie S, Lemkes JW, Westendorp RG | 2005-03-01 | International journal of geriatric psychiatry | |
| Meta-analysis of nonsteroidal antiinflammatory drug use and risk of dementia. | de Craen AJ, Gussekloo J, Vrijsen B, Westendorp RG | 2005-01-15 | American journal of epidemiology | |
| Does depression specifically increase cardiovascular mortality? | Vinkers DJ, Gussekloo J, Stek ML, van der Mast RC, Westendorp RG | 2005-01-10 | Archives of internal medicine | |
| A whole-genome scan for 24-hour respiration rate: a major locus at 10q26 influences respiration during sleep. | de Geus EJ, Posthuma D, Kupper N, van den Berg M, Willemsen G, Beem AL, Slagboom PE, Boomsma DI | 2005-01-01 | American journal of human genetics | |
| Variation in the human TP53 gene affects old age survival and cancer mortality. | van Heemst D, Mooijaart SP, Beekman M, Schreuder J, de Craen AJ, Brandt BW, Slagboom PE, Westendorp RG | 2005-01-01 | Experimental gerontology | |
| Is depression in old age fatal only when people feel lonely? | Stek ML, Vinkers DJ, Gussekloo J, Beekman AT, van der Mast RC, Westendorp RG | 2005-01-01 | The American journal of psychiatry | |
| In an observational study elderly patients had an increased risk of falling due to home hazards. | van Bemmel T, Vandenbroucke JP, Westendorp RG, Gussekloo J | 2005-01-01 | Journal of clinical epidemiology | |
| Phenotypic and functional characterization of CD4 T cells expressing killer Ig-like receptors. | van Bergen J, Thompson A, van der Slik A, Ottenhoff TH, Gussekloo J, Koning F | 2004-12-01 | Journal of immunology (Baltimore, Md. : 1950) | |
| Thyroid status, disability and cognitive function, and survival in old age. | Gussekloo J, van Exel E, de Craen AJ, Meinders AE, Frölich M, Westendorp RG | 2004-12-01 | JAMA | |
| Temporal relation between depression and cognitive impairment in old age: prospective population based study. | Vinkers DJ, Gussekloo J, Stek ML, Westendorp RG, van der Mast RC | 2004-10-16 | BMJ (Clinical research ed.) | |
| QTLs for height: results of a full genome scan in Dutch sibling pairs. | Willemsen G, Boomsma DI, Beem AL, Vink JM, Slagboom PE, Posthuma D | 2004-10-01 | European journal of human genetics : EJHG | |
| Does depression in old age increase only cardiovascular mortality? The Leiden 85-plus Study. | Vinkers DJ, Stek ML, Gussekloo J, Van Der Mast RC, Westendorp RG | 2004-09-01 | International journal of geriatric psychiatry | |
| Impaired innate immunity predicts frailty in old age. The Leiden 85-plus study. | van den Biggelaar AH, Huizinga TW, de Craen AJ, Gussekloo J, Heijmans BT, Frölich M, Westendorp RG | 2004-09-01 | Experimental gerontology | |
| Inflammation underlying cardiovascular mortality is a late consequence of evolutionary programming. | Van Den Biggelaar AH, De Craen AJ, Gussekloo J, Huizinga TW, Heijmans BT, Frölich M, Kirkwood TB, Westendorp RG | 2004-06-01 | FASEB journal : official publication of the Federation of American Societies for Experimental Biology | |
| [Causes and consequences of cognitive decline in the very elderly; the ‘Leiden 85-plus Study’]. | Gussekloo J, de Craen AJ, van Exel E, Bootsma-van der Wiel A, Westendorp RG | 2004-05-15 | Nederlands tijdschrift voor geneeskunde | |
| Insulin-like growth factor I gene promoter polymorphism, collagen type II alpha1 (COL2A1) gene, and the prevalence of radiographic osteoarthritis: the Rotterdam Study. | Zhai G, Rivadeneira F, Houwing-Duistermaat JJ, Meulenbelt I, Bijkerk C, Hofman A, van Meurs JB, Uitterlinden AG, Pols HA, Slagboom PE, van Duijn CM | 2004-05-01 | Annals of the rheumatic diseases | |
| Combined association and linkage analysis applied to the APOE locus. | Beekman M, Posthuma D, Heijmans BT, Lakenberg N, Suchiman HE, Snieder H, de Knijff P, Frants RR, van Ommen GJ, Kluft C, Vogler GP, Slagboom PE, Boomsma DI | 2004-05-01 | Genetic epidemiology | |
| Association of the interleukin-1 gene cluster with radiographic signs of osteoarthritis of the hip. | Meulenbelt I, Seymour AB, Nieuwland M, Huizinga TW, van Duijn CM, Slagboom PE | 2004-04-01 | Arthritis and rheumatism | |
| Further evidence for a QTL influencing body mass index on chromosome 7p from a genome-wide scan in Dutch families. | Heijmans BT, Beem AL, Willemsen G, Posthuma D, Slagboom PE, Boomsma D | 2004-04-01 | Twin research : the official journal of the International Society for Twin Studies | |
| Prevalence, correlates and recognition of depression in the oldest old: the Leiden 85-plus study. | Stek ML, Gussekloo J, Beekman AT, van Tilburg W, Westendorp RG | 2004-03-01 | Journal of affective disorders | |
| Variation in the SHC1 gene and longevity in humans. | Mooijaart SP, van Heemst D, Schreuder J, van Gerwen S, Beekman M, Brandt BW, Eline Slagboom P, Westendorp RG | 2004-02-01 | Experimental gerontology | |
| End-joining of blunt DNA double-strand breaks in mammalian fibroblasts is precise and requires DNA-PK and XRCC4. | van Heemst D, Brugmans L, Verkaik NS, van Gent DC | 2004-01-05 | DNA repair | |
| Linkage analysis of smoking initiation and quantity in Dutch sibling pairs. | Vink JM, Beem AL, Posthuma D, Neale MC, Willemsen G, Kendler KS, Slagboom PE, Boomsma DI | 2004-01-01 | The pharmacogenomics journal | |
| The 15-item Geriatric Depression Scale (GDS-15) detects changes in depressive symptoms after a major negative life event. The Leiden 85-plus Study. | Vinkers DJ, Gussekloo J, Stek ML, Westendorp RG, Van Der Mast RC | 2004-01-01 | International journal of geriatric psychiatry | |
| Interaction of atherosclerosis and inflammation in elderly subjects with poor cognitive function. | van Exel E, de Craen AJ, Remarque EJ, Gussekloo J, Houx P, Bootsma-van der Wiel A, Frölich M, Macfarlane PW, Blauw GJ, Westendorp RG | 2003-12-23 | Neurology | |
| Benzodiazepine use and risk of mortality in individuals aged 85 years or older. | Vinkers DJ, Gussekloo J, van der Mast RC, Zitman FG, Westendorp RG | 2003-12-10 | JAMA | |
| Evidence for a QTL on chromosome 19 influencing LDL cholesterol levels in the general population. | Beekman M, Heijmans BT, Martin NG, Whitfield JB, Pedersen NL, DeFaire U, Snieder H, Lakenberg N, Suchiman HE, de Knijff P, Frants RR, van Ommen GJ, Kluft C, Vogler GP, Boomsma DI, Slagboom PE | 2003-11-01 | European journal of human genetics : EJHG | |
| Walking and talking as predictors of falls in the general population: the Leiden 85-Plus Study. | Bootsma-van der Wiel A, Gussekloo J, de Craen AJ, van Exel E, Bloem BR, Westendorp RG | 2003-10-01 | Journal of the American Geriatrics Society | |
| Leisure activities and the risk of dementia. | Vinkers DJ, Gussekloo J, Westendorp RG | 2003-09-25 | The New England journal of medicine | |
| Two-locus linkage analysis applied to putative quantitative trait loci for lipoprotein(a) levels. | Beekman M, Heijmans BT, Martin NG, Whitfield JB, Pedersen NL, DeFaire U, Snieder H, Lakenberg N, de Knijff P, Frants RR, van Ommen GJ, Kluft C, Vogler GP, Slagboom PE, Boomsma DI | 2003-08-01 | Twin research : the official journal of the International Society for Twin Studies | |
| Prevalence of five common clinical abnormalities in very elderly people: population based cross sectional study. | de Craen AJ, Gussekloo J, Teng YK, Macfarlane PW, Westendorp RG | 2003-07-19 | BMJ (Clinical research ed.) | |
| High-density vs low-density lipoprotein cholesterol as the risk factor for coronary artery disease and stroke in old age. | Weverling-Rijnsburger AW, Jonkers IJ, van Exel E, Gussekloo J, Westendorp RG | 2003-07-14 | Archives of internal medicine | |
| Auditory rehabilitation of older people from the general population–the Leiden 85-plus study. | Gussekloo J, de Bont LE, von Faber M, Eekhof JA, de Laat JA, Hulshof JH, van Dongen E, Westendorp RG | 2003-07-01 | The British journal of general practice : the journal of the Royal College of General Practitioners | |
| Abnormal brain diffusivity in patients with neuropsychiatric systemic lupus erythematosus. | Bosma GP, Huizinga TW, Mooijaart SP, Van Buchem MA | 2003-05-01 | AJNR. American journal of neuroradiology | |
| A common variant of the methylenetetrahydrofolate reductase gene (1p36) is associated with an increased risk of cancer. | Heijmans BT, Boer JM, Suchiman HE, Cornelisse CJ, Westendorp RG, Kromhout D, Feskens EJ, Slagboom PE | 2003-03-15 | Cancer research | |
| Accuracy of the 15-item geriatric depression scale (GDS-15) in a community sample of the oldest old. | de Craen AJ, Heeren TJ, Gussekloo J | 2003-01-01 | International journal of geriatric psychiatry | |
| [An outbreak of vomiting and diarrhea in a nursing home caused by the Norwalk-like virus: implications of the Dutch law on infectious diseases and new diagnostic options]. | Achterberg WP, van Kessel RP | 2002-12-14 | Nederlands tijdschrift voor geneeskunde | |
| Atherosclerosis and cognitive impairment are linked in the elderly. The Leiden 85-plus Study. | van Exel E, Gussekloo J, Houx P, de Craen AJ, Macfarlane PW, Bootsma-van der Wiel A, Blauw GJ, Westendorp RG | 2002-12-01 | Atherosclerosis | |
| A high response is not essential to prevent selection bias: results from the Leiden 85-plus study. | der Wiel AB, van Exel E, de Craen AJ, Gussekloo J, Lagaay AM, Knook DL, Westendorp RG | 2002-11-01 | Journal of clinical epidemiology | |
| Organisation of the human genome and our tools for identifying disease genes. | Slagboom PE, Meulenbelt I | 2002-10-01 | Biological psychology | |
| No increase in mortality and morbidity among carriers of the C282Y mutation of the hereditary haemochromatosis gene in the oldest old: the Leiden 85-plus study. | Van Aken MO, De Craen AJ, Gussekloo J, Moghaddam PH, Vandenbroucke JP, Heijmans BT, Slagboom PE, Westendorp RG | 2002-10-01 | European journal of clinical investigation | |
| Common chronic diseases and general impairments as determinants of walking disability in the oldest-old population. | Bootsma-van der Wiel A, Gussekloo J, De Craen AJ, Van Exel E, Bloem BR, Westendorp RG | 2002-08-01 | Journal of the American Geriatrics Society | |
| Association of the tumour necrosis factor alpha -308G/A polymorphism with the risk of diabetes in an elderly population-based cohort. | Heijmans BT, Westendorp RG, Droog S, Kluft C, Knook DL, Slagboom PE | 2002-06-01 | Genes and immunity | |
| Association between high-density lipoprotein and cognitive impairment in the oldest old. | van Exel E, de Craen AJ, Gussekloo J, Houx P, Bootsma-van der Wiel A, Macfarlane PW, Blauw GJ, Westendorp RG | 2002-06-01 | Annals of neurology | |
| Heritabilities of apolipoprotein and lipid levels in three countries. | Beekman M, Heijmans BT, Martin NG, Pedersen NL, Whitfield JB, DeFaire U, van Baal GC, Snieder H, Vogler GP, Slagboom PE, Boomsma DI | 2002-04-01 | Twin research : the official journal of the International Society for Twin Studies | |
| Low production capacity of interleukin-10 associates with the metabolic syndrome and type 2 diabetes : the Leiden 85-Plus Study. | van Exel E, Gussekloo J, de Craen AJ, Frölich M, Bootsma-Van Der Wiel A, Westendorp RG | 2002-04-01 | Diabetes | |
| Inflammation and stroke: the Leiden 85-Plus Study . | van Exel E, Gussekloo J, de Craen AJ, Bootsma-van der Wiel A, Frölich M, Westendorp RG | 2002-04-01 | Stroke | |
| Different types of V(D)J recombination and end-joining defects in DNA double-strand break repair mutant mammalian cells. | Verkaik NS, Esveldt-van Lange RE, van Heemst D, Brüggenwirth HT, Hoeijmakers JH, Zdzienicka MZ, van Gent DC | 2002-03-01 | European journal of immunology | |
| Association of APOE epsilon2/epsilon3/epsilon4 and promoter gene variants with dementia but not cardiovascular mortality in old age. | Heijmans BT, Slagboom PE, Gussekloo J, Droog S, Lagaay AM, Kluft C, Knook DL, Westendorp RG | 2002-01-22 | American journal of medical genetics | |
| Cognitive function in the oldest old: women perform better than men. | van Exel E, Gussekloo J, de Craen AJ, Bootsma-van der Wiel A, Houx P, Knook DL, Westendorp RG | 2001-07-01 | Journal of neurology, neurosurgery, and psychiatry | |
| Disability in the oldest old: “can do” or “do do”? | Bootsma-van der Wiel A, Gussekloo J, de Craen AJ, van Exel E, Knook DL, Lagaay AM, Westendorp RG | 2001-07-01 | Journal of the American Geriatrics Society | |
| Improvements in the quality of co-ordination of nursing care following implementation of the Resident Assessment Instrument in Dutch nursing homes. | Achterberg WP, Holtkamp CC, Kerkstra A, Pot AM, Ooms ME, Ribbe MW | 2001-07-01 | Journal of advanced nursing | |
| Isolation and characterization of sexual sporulation mutants of Aspergillus nidulans. | Swart K, van Heemst D, Slakhorst M, Debets F, Heyting C | 2001-06-01 | Fungal genetics and biology : FG & B | |
| BimD/SPO76 is at the interface of cell cycle progression, chromosome morphogenesis, and recombination. | van Heemst D, Kafer E, John T, Heyting C, van Aalderen M, Zickler D | 2001-05-22 | Proceedings of the National Academy of Sciences of the United States of America | |
| A powerful and rapid approach to human genome scanning using small quantities of genomic DNA. | Beekman M, Lakenberg N, Cherny SS, de Knijff P, Kluft CC, van Ommen GJ, Vogler GP, Frants RR, Boomsma DI, Slagboom PE | 2001-04-01 | Genetical research | |
| Netherlands twin family study of anxious depression (NETSAD). | Boomsma DI, Beem AL, van den Berg M, Dolan CV, Koopmans JR, Vink JM, de Geus EJ, Slagboom PE | 2000-12-01 | Twin research : the official journal of the International Society for Twin Studies | |
| Detection of sequence variability of the collagen type IIalpha 1 3′ variable number of tandem repeat. | van Meurs JB, Arp PP, Fang Y, Slagboom PE, Meulenbelt I, van Leeuwen JP, Pols HA, Uitterlinden AG | 2000-11-01 | Electrophoresis | |
| Zygosity diagnosis in young twins by parental report. | Rietveld MJ, van Der Valk JC, Bongers IL, Stroet TM, Slagboom PE, Boomsma DI | 2000-09-01 | Twin research : the official journal of the International Society for Twin Studies | |
| Common gene variants, mortality and extreme longevity in humans. | Heijmans BT, Westendorp RG, Slagboom PE | 2000-09-01 | Experimental gerontology | |
| Idiopathic senile gait disorders are signs of subclinical disease. | Bloem BR, Gussekloo J, Lagaay AM, Remarque EJ, Haan J, Westendorp RG | 2000-09-01 | Journal of the American Geriatrics Society | |
| Genetics of human aging. The search for genes contributing to human longevity and diseases of the old. | Slagboom PE, Heijmans BT, Beekman M, Westendorp RG, Meulenbelt I | 2000-06-01 | Annals of the New York Academy of Sciences | |
| C-reactive protein is a strong but nonspecific risk factor of fatal stroke in elderly persons. | Gussekloo J, Schaap MC, Frölich M, Blauw GJ, Westendorp RG | 2000-04-01 | Arteriosclerosis, thrombosis, and vascular biology | |
| Common paraoxonase gene variants, mortality risk and fatal cardiovascular events in elderly subjects. | Heijmans BT, Westendorp RG, Lagaay AM, Knook DL, Kluft C, Slagboom PE | 2000-03-01 | Atherosclerosis | |
| Sister chromatid cohesion and recombination in meiosis. | van Heemst D, Heyting C | 2000-01-01 | Chromosoma | |
| Angiotensin I-converting enzyme and plasminogen activator inhibitor-1 gene variants: risk of mortality and fatal cardiovascular disease in an elderly population-based cohort. | Heijmans BT, Westendorp RG, Knook DL, Kluft C, Slagboom PE | 1999-10-01 | Journal of the American College of Cardiology | |
| Thermolabile methylenetetrahydrofolate reductase gene and the risk of cognitive impairment in those over 85. | Gussekloo J, Heijmans BT, Slagboom PE, Lagaay AM, Knook DL, Westendorp RG | 1999-10-01 | Journal of neurology, neurosurgery, and psychiatry | |
| Haplotype analysis of three polymorphisms of the COL2A1 gene and associations with generalised radiological osteoarthritis. | Meulenbelt I, Bijkerk C, De Wildt SC, Miedema HS, Breedveld FC, Pols HA, Hofman A, Van Duijn CM, Slagboom PE | 1999-09-01 | Annals of human genetics | |
| Effects of the Resident Assessment Instrument on the care process and health outcomes in nursing homes. A review of the literature. | Achterberg WP, van Campen C, Pot AM, Kerkstra A, Ribbe MW | 1999-09-01 | Scandinavian journal of rehabilitation medicine | |
| Variation in plasminogen-activator-inhibitor-1 gene and risk of meningococcal septic shock. | Westendorp RG, Hottenga JJ, Slagboom PE | 1999-08-14 | Lancet (London, England) | |
| Heritabilities of radiologic osteoarthritis in peripheral joints and of disc degeneration of the spine. | Bijkerk C, Houwing-Duistermaat JJ, Valkenburg HA, Meulenbelt I, Hofman A, Breedveld FC, Pols HA, van Duijn CM, Slagboom PE | 1999-08-01 | Arthritis and rheumatism | |
| Spo76p is a conserved chromosome morphogenesis protein that links the mitotic and meiotic programs. | van Heemst D, James F, Pöggeler S, Berteaux-Lecellier V, Zickler D | 1999-07-23 | Cell | |
| Mortality risk in men is associated with a common mutation in the methylene-tetrahydrofolate reductase gene (MTHFR). | Heijmans BT, Gussekloo J, Kluft C, Droog S, Lagaay AM, Knook DL, Westendorp RG, Slagboom EP | 1999-02-01 | European journal of human genetics : EJHG | |
| The risk of mortality and the factor V Leiden mutation in a population-based cohort. | Heijmans BT, Westendorp RG, Knook DL, Kluft C, Slagboom PE | 1998-10-01 | Thrombosis and haemostasis | |
| A genetic association study of the IGF-1 gene and radiological osteoarthritis in a population-based cohort study (the Rotterdam Study). | Meulenbelt I, Bijkerk C, Miedema HS, Breedveld FC, Hofman A, Valkenburg HA, Pols HA, Slagboom PE, van Duijn CM | 1998-06-01 | Annals of the rheumatic diseases | |
| Response to activated protein C in subjects with and without dementia. The Dutch Vascular Factors in Dementia Study. | Bots ML, van Kooten F, Breteler MM, Slagboom PE, Hofman A, Haverkate F, Meijer P, Koudstaal PJ, Grobbee DE, Kluft C | 1998-05-01 | Haemostasis | |
| Genetic linkage analysis of 14 candidate gene loci in a family with autosomal dominant osteoarthritis without dysplasia. | Meulenbelt I, Bijkerk C, Breedveld FC, Slagboom PE | 1997-12-01 | Journal of medical genetics | |
| Impact of mild cognitive impairment on survival in very elderly people: cohort study. | Gussekloo J, Westendorp RG, Remarque EJ, Lagaay AM, Heeren TJ, Knook DL | 1997-10-25 | BMJ (Clinical research ed.) | |
| Investigation of the association of the CRTM and CRTL1 genes with radiographically evident osteoarthritis in subjects from the Rotterdam study. | Meulenbelt I, Bijkerk C, de Wildt SC, Miedema HS, Valkenburg HA, Breedveld FC, Pols HA, Te Koppele JM, Sloos VF, Hofman A, Slagboom PE, van Duijn CM | 1997-10-01 | Arthritis and rheumatism | |
| Normal prevalence of factor V Leiden gene mutation in patients with severe unstable angina. | Verheggen PW, Heymans BT, Slagboom PE, Haverkate F, Cats VM | 1997-06-01 | Thrombosis and haemostasis | |
| Cloning, sequencing, disruption and phenotypic analysis of uvsC, an Aspergillus nidulans homologue of yeast RAD51. | van Heemst D, Swart K, Holub EF, van Dijk R, Offenberg HH, Goosen T, van den Broek HW, Heyting C | 1997-05-01 | Molecular & general genetics : MGG | |
| [Direct antibiotic sensitivity testing in the treatment of urinary tract infections in a nursing home]. | Achterberg WP, Peerbooms PG, Brühl KG | 1997-02-01 | Tijdschrift voor gerontologie en geriatrie | |
| Reduced response to activated protein C is associated with increased risk for cerebrovascular disease. | van der Bom JG, Bots ML, Haverkate F, Slagboom PE, Meijer P, de Jong PT, Hofman A, Grobbee DE, Kluft C | 1996-08-15 | Annals of internal medicine | |
| Population haplotype analysis and evolutionary relations of the COL2A1 gene. | Meulenbelt I, Williams CJ, Te Koppele JM, Van de Giessen GC, Slagboom PE | 1996-05-01 | Annals of human genetics | |
| High-yield noninvasive human genomic DNA isolation method for genetic studies in geographically dispersed families and populations. | Meulenbelt I, Droog S, Trommelen GJ, Boomsma DI, Slagboom PE | 1995-11-01 | American journal of human genetics | |
| A community based study of the incidence of dementia in subjects aged 85 years and over. | Gussekloo J, Heeren TJ, Izaks GJ, Ligthart GJ, Rooijmans HG | 1995-11-01 | Journal of neurology, neurosurgery, and psychiatry | |
| Three-year follow-up of Mini-Mental State Examination score in community residents aged 85 and over. | Izaks GJ, Gussekloo J, Dermout KM, Heeren TJ, Ligthart GJ | 1995-07-01 | Psychological medicine | |
| Genetic determination of telomere size in humans: a twin study of three age groups. | Slagboom PE, Droog S, Boomsma DI | 1994-11-01 | American journal of human genetics | |
| The dynamics of genome organization and expression during the aging process. | Slagboom PE, Vijg J | 1992-12-26 | Annals of the New York Academy of Sciences | |
| Methylation status of cKi-ras and MHC genes in rat pituitary glands during aging and tumorigenesis. | Slagboom PE, Uitterlinden AG, Vijg J | 1991-06-01 | Aging (Milan, Italy) | |
| Somatic mutations and cellular aging: two-dimensional DNA typing of rat fibroblast clones. | Slagboom PE, Mullaart E, Droog S, Vijg J | 1991-03-01 | Mutation research | |
| DNA processing, aging, and cancer. The impact of new technology. | Vijg J, Gossen JA, De Leeuw WJ, Mullaart E, Slagboom PE, Uitterlinden AG | 1991-01-01 | Annals of the New York Academy of Sciences | |
| mRNA levels and methylation patterns of the tyrosine aminotransferase gene in aging inbred rats. | Slagboom PE, de Leeuw WJ, Vijg J | 1990-08-20 | FEBS letters | |
| The aging genome: determinant or target? Report of the EURAGE meeting on ‘Genomic Instability and Aging’, Nerja (Spain). | Slagboom PE | 1990-05-01 | Mutation research | |
| Messenger RNA levels and methylation patterns of GAPDH and beta-actin genes in rat liver, spleen and brain in relation to aging. | Slagboom PE, de Leeuw WJ, Vijg J | 1990-04-30 | Mechanisms of ageing and development | |
| Quantitative comparison of mRNA levels in mammalian tissues: 28S ribosomal RNA level as an accurate internal control. | de Leeuw WJ, Slagboom PE, Vijg J | 1989-12-11 | Nucleic acids research | |
| The Caenorhabditis elegans genome contains monomorphic minisatellites and simple sequences. | Uitterlinden AG, Slagboom PE, Johnson TE, Vijg J | 1989-12-11 | Nucleic acids research | |
| Two-dimensional DNA fingerprinting of human individuals. | Uitterlinden AG, Slagboom PE, Knook DL, Vijg J | 1989-04-01 | Proceedings of the National Academy of Sciences of the United States of America | |
| Genetic instability and aging: theories, facts, and future perspectives. | Slagboom PE, Vijg J | 1989-01-01 | Genome | |
| DNA methods for detecting and analyzing mutations in vivo. | Lohman PH, Vijg J, Uitterlinden AG, Slagboom P, Gossen JA, Berends F | 1987-12-01 | Mutation research | |
| Sequence heterogeneity within the human alphoid repetitive DNA family. | Devilee P, Slagboom P, Cornelisse CJ, Pearson PL | 1986-03-11 | Nucleic acids research | |
| Two subsets of human alphoid repetitive DNA show distinct preferential localization in the pericentric regions of chromosomes 13, 18, and 21. | Devilee P, Cremer T, Slagboom P, Bakker E, Scholl HP, Hager HD, Stevenson AF, Cornelisse CJ, Pearson PL | 1986-01-01 | Cytogenetics and cell genetics | |
| Genetics and behavioral medicine: risk factors for cardiovascular disease. | Vogler GP, McClearn GE, Snieder H, Boomsma DI, Palmer R, de Knijff P, Slagboom PE | 1970-01-01 | Behavioral medicine (Washington, D.C.) | |
| The necessity for research on the elderly in iran. | Shafiee A, van Bodegom D | 1970-01-01 | The journal of Tehran Heart Center | |
| Successful aging in the oldest old: Who can be characterized as successfully aged? | von Faber M, Bootsma-van der Wiel A, van Exel E, Gussekloo J, Lagaay AM, van Dongen E, Knook DL, van der Geest S, Westendorp RG | 1970-01-01 | Archives of internal medicine | |
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Last update: September 8th, 2024 on 00:12