Background

The aim is to describe the association of functional capacity and cognitive functioning with 1-year mortality in older patients with cancer in the head and neck region.

Methods

We performed a cohort study in which all patients aged 70 years and older received a geriatric screening before treatment. Main outcome was 1-year mortality.

Results

A total of 102 patients were included. Median age was 78.7 years (interquartile range [IQR], 72.3-84.5), 25% were cognitive impaired, 40% were malnourished, and 28.4% used a walking device. Overall, 1-year mortality was 42.3%. Male sex (hazard ratio [HR], 4.30; 95% confidence interval [CI], 1.35-13.67), malnutrition (HR, 2.55; 95% CI, 1.19-5.16), and using a walking device (HR, 2.80; 95% CI 1.13-6.93) were associated with higher mortality risk, independent of stage and comorbidities.

Conclusion

In older patients with head and neck cancer, the mortality rates are high. Nutritional status and mobility are determinants of 1-year mortality, independent of tumor stage, age, and comorbidity.

© 2019 The Authors. Head & Neck published by Wiley Periodicals, Inc.

Overview publication

TitleGeriatric assessment and 1-year mortality in older patients with cancer in the head and neck region: A cohort study.
DateAugust 1st, 2019
Issue nameHead & neck
Issue numberv41.8:2477-2483
DOI10.1002/hed.25714
PubMed30816619
Authorsvan Deudekom FJ, van der Velden LA, Zijl WH, Schimberg AS, Langeveld AP, Slingerland M, Blauw GJ & Mooijaart SP
Keywordscognitive disorders, geriatric oncology, head and neck cancer, physical functioning, social functioning
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